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Dr. Judith Campisi, Ph.D.

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Aging-USAging-USCall for Papers: Commemorative Collection Honoring Dr. Judith CampisiAging (Aging-US) invites #submissions for a Special Collection dedicated to the theme of cellular #senescence, spanning its basic mechanisms, physiological and pathological functions, and clinical applications. This collection is published in memory of Professor Judith Campisi, a pioneering force in the field of cellular senescence whose groundbreaking work shaped the understanding of senescence in aging, cancer, and tissue homeostasis. Her legacy continues to inspire generations of scientists working to decode the complex biology of senescent cells and their impact on health and disease. We welcome original research articles, reviews, and perspectives on topics including: -Fundamental mechanisms of senescence induction and...2025-05-0101 minAging-USAging-USDr. Marco Demaria Named Editor-In-Chief of Aging (Aging-US)BUFFALO, NY- December 19, 2024 – We are pleased to announce that Dr. Marco Demaria, a leading expert in aging and cellular senescence, will join Aging (Aging-US) as Editor-in-Chief, starting January 1, 2025. Dr. Demaria will work alongside an esteemed Editorial Board. Dr. Demaria has an impressive background in aging research. He earned his PhD in Molecular Medicine from the University of Torino, Italy. In 2010, he joined the laboratory of Aging Founding Editor, the late Dr. Judith Campisi, at the Buck Institute for Research on Aging. There he developed cellular and animal models for studying cellular aging, also known as cellular senescence, and its role in...2024-12-1903 minAging-USAging-USUV-A Exposure, Cellular Senescence, and Vision ImpairmentWith an ever-increasing global population grappling with age-related ocular ailments like cataracts, dry eyes, glaucoma, and macular degeneration, the need for new research in this domain is more pressing than ever. In a new study, researchers Kohsaku Numa, Sandip Kumar Patel, Zhixin A. Zhang, Jordan B. Burton, Akifumi Matsumoto, Jun-Wei B. Hughes, Chie Sotozono, Birgit Schilling, Pierre-Yves Desprez, Judith Campisi (1948-2024), and Koji Kitazawa from the Buck Institute for Research on Aging, Kyoto Prefectural University of Medicine, University of Cambridge, and California Pacific Medical Center shed light on a pivotal aspect of corneal health – the impact of ultraviolet-A (UV-A) radiation on...2024-05-0206 minAging-USAging-USCover Paper: Senescent Characteristics of Human Corneal Endothelial Cells Upon UV-A ExposureBUFFALO, NY- April 30, 2024 – A new #researchpaper was #published on the #cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 8, entitled, “Senescent characteristics of human corneal endothelial cells upon ultraviolet-A exposure.” In this new study, researchers Kohsaku Numa, Sandip Kumar Patel, Zhixin A. Zhang, Jordan B. Burton, Akifumi Matsumoto, Jun-Wei B. Hughes, Chie Sotozono, Birgit Schilling, Pierre-Yves Desprez, Judith Campisi (1948-2024), and Koji Kitazawa from Buck Institute for Research on Aging, Kyoto Prefectural University of Medicine, University of Cambridge, and California Pacific Medical Center investigated the senescent phenotypes of human corneal endoth...2024-04-3004 minAging-USAging-USAging-Related Fibro-Inflammatory Signature in Mouse OvariesBUFFALO, NY- October 31, 2023 – A new priority research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 20, entitled, “Proteomic quantification of native and ECM-enriched mouse ovaries reveals an age-dependent fibro-inflammatory signature.” The ovarian microenvironment becomes fibrotic and stiff with age, in part due to increased collagen and decreased hyaluronan. However, the extracellular matrix (ECM) is a complex network of hundreds of proteins, glycoproteins, and glycans which are highly tissue specific and undergo pronounced changes with age. In this new study, researchers Shweta S. Dipali, Christina D. King...2023-10-3104 minAging-USAging-USGenetic Profiles of Senescent Corneal and Conjunctival Epithelial Cells in HumansBUFFALO, NY- October 2, 2023 – A new priority research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 18, entitled, “Gene expression signatures of human senescent corneal and conjunctival epithelial cells.” In this new study, researchers Koji Kitazawa, Akifumi Matsumoto, Kohsaku Numa, Yasufumi Tomioka, Zhixin A. Zhang, Yohei Yamashita, Chie Sotozono, Pierre-Yves Desprez, and Judith Campisi from the Buck Institute for Research on Aging, Kyoto Prefectural University of Medicine and Lawrence Berkeley National Laboratory aimed to investigate the senescent phenotypes of human corneal and conjunctival epithelial cells. “Here, we induc...2023-10-0203 minNaukowoNaukowoZabawy trzmieli, księżycowe cegły, komórki zombie i efekt motyla - #064Czy trzmiele potrafią się dobrze bawić, jak to robią i właściwie po co? Czym są "komórki zombie" wewnątrz naszych organizmów i czy mogą spełniać jakieś pożyteczne funkcje? W sobotnim wydaniu podkastu Naukowo zabiorę Was też w podróż na Księżyc, gdzie będziemy wypalać cegły oraz nieco bliżej - do ziemskiej atmosfery pełnej naelektryzowanych owadów. A jeśli odcinek Ci się spodoba udostępnij go, proszę, dalej i subskrybuj podkast gdziekolwiek go słuchasz, możesz też prosto i szybko postawić mi dobrą kawę - buycoffee.to/naukowo - z góry dziękuję :)2022-10-2920 minThe Joy of WhyThe Joy of WhyWhy Do We Get Old, and Can Aging Be Reversed?Everybody gets older, but not everyone ages in the same way. In this episode, Steven Strogatz speaks with Judith Campisi and Dena Dubal, two biomedical researchers who study the causes and outcomes of aging, to understand how age works - and what scientists know about postponing or even reversing the aging process.2022-07-2738 minModern HealthspanModern HealthspanThe Future Of Aging & Unity Biotech - Professor Judith Campisi Interview Series Ep 8/8In this video Professor Campisi talks her personal protocol for staying healthy and some of the research that her lab is now working on. The Campisi lab at the Buck Institute https://www.buckinstitute.org/lab/campisi-lab/ Judith Campisi is a professor of biogerontology at the Buck Institute for Research on Aging. She is co-editor in chief of the Aging Journal, and founder of the pharmaceutical company Unity Biotechnology. Prof Campisi is widely recognized for her work on senescent cells and their influence on many manifestations of aging. Her laboratory discovered Senescence Associated...2021-12-2910 minModern HealthspanModern HealthspanMy Health Protocol & Latest Lab Research - Professor Judith Campisi Interview Series 7In this video Professor Campisi talks her personal protocol for staying healthy and some of the research that her lab is now working on. The Campisi lab at the Buck Institute https://www.buckinstitute.org/lab/campisi-lab/ Judith Campisi is a professor of biogerontology at the Buck Institute for Research on Aging. She is co-editor in chief of the Aging Journal, and founder of the pharmaceutical company Unity Biotechnology. Prof Campisi is widely recognized for her work on senescent cells and their influence on many manifestations of aging. Her laboratory discovered Senescence Associated...2021-12-2606 minModern HealthspanModern HealthspanLifestyles To Minimize Senescent Cells - Professor Judith Campisi Interview Series Ep6In this video Professor Campisi talks about what lifestyle habits can minimize the senescent cells in our body. The Campisi lab at the Buck Institute https://www.buckinstitute.org/lab/campisi-lab/ Judith Campisi is a professor of biogerontology at the Buck Institute for Research on Aging. She is co-editor in chief of the Aging Journal, and founder of the pharmaceutical company Unity Biotechnology. Prof Campisi is widely recognized for her work on senescent cells and their influence on many manifestations of aging. Her laboratory discovered Senescence Associated Secretory Phenotype (SASP) and also discovered...2021-12-2306 minModern HealthspanModern HealthspanNew Biomarker For Senolytics - Professor Judith Campisi Interview Series Ep5In this video Professor Campisi talks about why detecting senescent cells is difficult and the biomarker that her team recently found that shows how effective a senolytic is and can also be used to determine the level of senescent burden. The Campisi lab at the Buck Institute https://www.buckinstitute.org/lab/campisi-lab/ Judith Campisi is a professor of biogerontology at the Buck Institute for Research on Aging. She is co-editor in chief of the Aging Journal, and founder of the pharmaceutical company Unity Biotechnology. Prof Campisi is widely recognized for her work...2021-12-1905 minModern HealthspanModern HealthspanSenescent Cells & Age Related Diseases _ Professor Judith Campisi Interview Series Ep4In this video Professor Campisi talks about how senescent cells are heterogeneous and their interaction with the immune system which leads to inflammaging. The Campisi lab at the Buck Institute https://www.buckinstitute.org/lab/campisi-lab/ Judith Campisi is a professor of biogerontology at the Buck Institute for Research on Aging. She is co-editor in chief of the Aging Journal, and founder of the pharmaceutical company Unity Biotechnology. Prof Campisi is widely recognized for her work on senescent cells and their influence on many manifestations of aging. Her laboratory discovered Senescence Associated Secretory...2021-12-1406 minModern HealthspanModern HealthspanSenescent Cells & Inflammaging - Professor Judith Campisi Interview Series Ep3In this video Professor Campisi talks about how senescent cells are heterogeneous and their interaction with the immune system which leads to inflammaging. The Campisi lab at the Buck Institute https://www.buckinstitute.org/lab/campisi-lab/ Judith Campisi is a professor of biogerontology at the Buck Institute for Research on Aging. She is co-editor in chief of the Aging Journal, and founder of the pharmaceutical company Unity Biotechnology. Prof Campisi is widely recognized for her work on senescent cells and their influence on many manifestations of aging. Her laboratory discovered Senescence Associated Secretory...2021-12-1208 minModern HealthspanModern HealthspanSenescent Cells & Senolytics _ Professor Judith Campisi Interview Series Ep2In this video Professor Campisi talks why we have senescent cells, a possible schedule for taking senolytics, and senescent cells and cancer. The Campisi lab at the Buck Institute https://www.buckinstitute.org/lab/campisi-lab/ Judith Campisi is a professor of biogerontology at the Buck Institute for Research on Aging. She is co-editor in chief of the Aging Journal, and founder of the pharmaceutical company Unity Biotechnology. Prof Campisi is widely recognized for her work on senescent cells and their influence on many manifestations of aging. Her laboratory discovered Senescence Associated Secretory Phenotype...2021-12-0809 minModern HealthspanModern HealthspanMy Theory Of Aging Professor Judith Campisi Interview Series Ep1In this video Professor Campisi talks about what led her to study aging. She also covers her ideas on why we age and how senescent cells fit into that. The Campisi lab at the Buck Institute https://www.buckinstitute.org/lab/campisi-lab/ Judith Campisi is a professor of biogerontology at the Buck Institute for Research on Aging. She is co-editor in chief of the Aging Journal, and founder of the pharmaceutical company Unity Biotechnology. Prof Campisi is widely recognized for her work on senescent cells and their influence on many manifestations of aging...2021-12-0512 minProgress, Potential, and Possibilities Podcast / ShowProgress, Potential, and Possibilities Podcast / ShowDr. Judith Campisi, Ph.D. - Professor of Biogerontology - Buck Institute for Research on AgingSend us a textDr. Judith Campisi, PhD (https://www.buckinstitute.org/lab/campisi-lab/) is a biochemist, cell biologist, and Professor of Biogerontology at the Buck Institute for Research on Aging. Dr. Campisi received a PhD in biochemistry from the State University of New York at Stony Brook and completed her postdoctoral training in cell cycle regulation at the Dana-Farber Cancer Institute and Harvard Medical School. As an assistant and associate professor at the Boston University Medical School, she studied the role of cellular senescence in suppressing cancer and soon became convinced that senescent cells also contributed...2021-11-2451 minWhat\'s Next|科技早知道What's Next|科技早知道S5E29|重金押注抗衰老公司,硅谷真的可以做出长生不老药吗?2021 年 9 月 4 日,《麻省理工科技评论》发布报道,称亚马逊创始人 Jeff Bezos 和硅谷著名投资人 Yuri Milner 在近期投资了专注于抗衰方向的生物科技公司 Altos Labs,一家今年四月才成立的抗衰老公司,科学家团队包括 2012 年诺贝尔生理学或医学奖的获得者山中伸弥;截至今年六月,该公司已经吸引了至少 2.7 亿美元的投资。这并非硅谷富豪们第一次入局抗衰领域。 2018 年, Jeff Bezos 和 PayPal 联合创始人 Peter Thiel 共同投资抗衰领域独角兽 Unity Biotechnology;而更早之前,还有谷歌创始人 Larry Page 宣布 10 亿美元投资生物科技公司 Calico,目前 Calico 已经被整合至谷歌母公司 Alphabet Inc。我们似乎可以清晰地看见,在颠覆互联网、物流制造、航空航天等领域之后,硅谷大佬们的下一个目标,正是通过生物工程技术突破人类目前的寿命上限,将长生不老的选择权紧紧握在手里。 本期节目,我们邀请到了同样在抗衰领域被视为明星公司的硅谷新贵 Gordian 的首席科学家 Martin Borch Jensen。他和主播 Diane 一起探讨了硅谷的投资者们都是出于什么原因投资 Altos Labs 等生物科技公司,值得关注技术路径有哪些,投资人应该如何看待生物科技领域的超长投资周期和技术挑战,头部公司可以通过什么途径实现商业回报。 #加入我们# 声动活泼正在招聘「内容研究员」、「业务拓展和合作管理总监/经理」、「声音设计师」、「播客制作实习生」、「内容营销负责人」及「节目制作人」,查看详细讯息请在公号「声动活泼」回复暗号:入场券 。简历接收邮箱📮 hr@shengfm.cn 。 ▼主播 丁教,声动活泼联合创始人 ▼嘉宾 Martin Borch Jensen,Gordian 首席科学家 ▼主要话题 [02:24] 本期节目的亮点总结 [09:03] Gordian 是什么样的生物科技公司? [10:30] 大牛辈出的巴克研究所在抗衰科研领域是什么样的存在?抗衰领域的生物科技初创公司应该选择在西海岸还是东海岸? [14:34] 为什么抗衰领域会引来硅谷富豪的投资热潮? [17:53] Elysium 推出的膳食补充剂 Basis 真的可以抗衰吗? [19:50] 抗衰的主流技术路径都有哪些? [27:03] 像 BioViVa 的 CEO 给自己注射抗衰药物的事情常见吗? [27:57] 除了富豪们的家族信托基金,还有哪些投资机构关注这个赛道?什么时候看见回报? [30:55] 抗衰公司为什么在二级市场不吃香?临床实验失败有多常见? [35:30] 如何理解 Gordian 这样的平台型公司的商业模式?谷歌麾下的 Calico 值得期待吗? [40:58] 抗衰领域在面临哪些挑战?衰老标志物会如何促进抗衰研究的发展?抗衰进程已经走到哪一步了? [48:30] 有什么人人皆可尝试的长寿小秘诀? ▼延伸阅读 Meet Altos Labs, Silicon Valley’s latest wild bet on living forever Mutation Doubles Life Span In Worms A month after losing its lead program, Unity Biotechnology cuts 30% of staff in restructuring 雷帕霉素( Rapamycin, RAPA ):一种临床使用的免疫抑制剂,常用于肾移植抗排异治疗和肾癌治疗;1994 年发现抑制雷帕霉素靶点(Mechanistic Target of Rapamycin,mTOR)可调控细胞的存活,2009 年被证明可用于肝硬化及肝功能退化、阿尔茨海默症等并重的治疗,现为主流的长寿药之一 靶向清除衰老细胞的药物( Senolytics ):尚无正式的中文译名,2015 年在《 Aging Cells 》上首次出现,由 CAR-T 细胞改造为可定向清除衰老细胞的小分子药剂,其中达沙替尼+槲皮素( Dasatinib plus Quercetin, D+Q )的联合用药在 2018 年的小鼠实验中被证明可以成功清除衰老细胞,Unity Biotechnology 的 Judith Campisi 设计出 Senolytics 药剂 UBX0101,尚未通过 II 期临床试验 二甲双胍靶向治疗衰老( Targeting Aging with Metformin,TAME ):二甲双胍在1922年首次被人工合成,常见于糖尿病治疗和预防,后被发现可用于延缓衰老,抗衰机制包括通过代谢途径激活AMPK(一种蛋白质激酶,可调控能量平衡)、通过抗氧化途径抑制线粒体I型复合体电子传递系统 重编程技术:被认为是逆转衰老的重要手段之一,可通过诱导性多能干细胞( Induced pluripotent stem cell,iPS )的技术对细胞进行重新编程,清除细胞的表观遗传记忆并让细胞变得年轻,但也有实验证明该技术可能加速癌症并发 巴克衰老研究所( Buck Institute for Research on aging ):非盈利的独立生物医学研究所,1999年成立,是全世界第一个专注于衰老领域的研究所,2018 年与 Insilico、Juvenescence 联合创立 Napa Therapeutics,推进 NAD+ 抗衰药物研发,该研究所也是世界上第一家研究衰老干预过程的研究所,Unity Biotechlogy 的联合创始人 Judith Campisi 目前仍在该所任职 Gordian:抗衰老领域的创新药服务商,2018 年成立,投资方包括 The Longevity Fund、Formic Ventures、谷歌 AI 负责人 Jeff Dean,主要为抗衰领域药企的研发和实验提供测试平台和量化模型,可比公司包括 Genentech、Atomwise Atomwise:AI 医疗公司,通过 AI 进行药物设计并销售相关药品给厂商,并对药物的收入按一定比例收取佣金,类似的公司还有 Exscientia、InSilico Medicine Genentech:中文译名基因泰克,起家于 DNA 重组技术的生物科技公司,1976 年由诺奖获得者 Herbert Boyer 联合风险投资人 Kleiner Perkins 创立,1980 年在纳斯达克上市,代表产品包括 Avastin 抗癌药物,与 Gordian 的商业模式类似,2009 年被瑞士罗氏制药公司以468亿美元的价格收购 Elysium Health:膳食补充剂公司,2014 年成立,科学家顾问团包括神经生理学家 Thomas C. Südhof 等多位诺奖得主,代表产品包括 NAD+ 类保健品 Basis(主要成分为烟酰胺核糖和紫檀芪),该产品未经过FDA的药品审批程序,类似的 NMN 产品在国内也未获得监管的生产批准许可 Altos Labs:专注于干细胞重编程的抗衰生物技术公司,2021 年成立,2021 年诺贝尔生理学或医学奖的获得者山中伸弥和甲基化生理年龄时钟之父 Steve Horvath 均为科学顾问委员会成员,贝佐斯投资标的之一,类似的技术方向还有AgeX等主2021-10-2053 minAging-USAging-USA New Marker of Aging and Cellular SenescenceListen to a blog summary of this research paper published by Aging, entitled, "Cdkn1a transcript variant 2 is a marker of aging and cellular senescence." The phenomenon in which cells are still metabolically active but can no longer proliferate is known as cellular senescence. Cellular senescence is a normal mechanism in development and tissue homeostasis—and a hallmark of aging. “Most of my lab works on a process called cellular senescence, which is a cellular response to stresses and damage, many of which increase with age,” Dr. Judy Campisi, Professor at the Buck Institute for Research on Aging and Senior Scient...2021-08-0206 minAging-USAging-USAging: Cdkn1a transcript Variant 2 is a Marker of Aging and Cellular SenescenceAging published "Cdkn1a transcript variant 2 is a marker of aging and cellular senescence" which reported that cellular senescence is a cell fate response characterized by a permanent cell cycle arrest driven primarily the by cell cycle inhibitor and tumor suppressor proteins p16Ink4a and p21Cip1/Waf1. In mice, the p21Cip1/Waf1 encoding locus, Cdkn1a, is known to generate two transcripts that produce identical proteins, but one of these transcript variants is poorly characterized. The authors show that the Cdkn1a transcript variant 2, but not the better-studied variant 1, is selectively elevated during natural aging across multiple...2021-07-2603 minAging-USAging-USCdkn1a Transcript Variant 2 is a Marker of Aging and Cellular SenescenceAging published "Cdkn1a transcript variant 2 is a marker of aging and cellular senescence" which reported that cellular senescence is a cell fate response characterized by a permanent cell cycle arrest driven primarily the by cell cycle inhibitor and tumor suppressor proteins p16Ink4a and p21Cip1/Waf1. In mice, the p21Cip1/Waf1 encoding locus, Cdkn1a, is known to generate two transcripts that produce identical proteins, but one of these transcript variants is poorly characterized. The authors show that the Cdkn1a transcript variant 2, but not the better-studied variant 1, is selectively elevated during natural aging across multiple...2021-07-2603 minAging-USAging-USAging: Participating in the AACR 2021 Annual MeetingAging is indexed by PubMed/Medline abbreviated as “Aging (Albany NY)”, PubMed Central, ISI/Web of Science: Science Citation Index Expanded (abbreviated as Aging‑US and listed in the Cell Biology category; since June 2017 it has also been listed in the Geriatrics & Gerontology category), and Scopus /Rank Q1 (abbreviated as Aging). Every year, the American Association for Cancer Research (AACR) organizes a conference program that covers the latest discoveries in cancer research. Topics include population science and prevention, cancer biology, translational and clinical studies, survivorship, and advocacy. This conference aims to highlight work from the best minds in research and medici...2021-04-0204 minAging-USAging-USAging: Participating in the AACR 2021 Annual MeetingAging is indexed by PubMed/Medline abbreviated as “Aging (Albany NY)”, PubMed Central, ISI/Web of Science: Science Citation Index Expanded (abbreviated as Aging‑US and listed in the Cell Biology category; since June 2017 it has also been listed in the Geriatrics & Gerontology category), and Scopus /Rank Q1 (abbreviated as Aging). Every year, the American Association for Cancer Research (AACR) organizes a conference program that covers the latest discoveries in cancer research. Topics include population science and prevention, cancer biology, translational and clinical studies, survivorship, and advocacy. This conference aims to highlight work from the best minds in research and medici...2021-04-0204 minHashtag Health: A Health and Medical PodcastHashtag Health: A Health and Medical Podcast# LONGEVITY - Senolytic Drugs, Caloric Restriction and the Aging CellIn this episode of Hashtag Health, we talk with geriatrician Dr. Laura Diachun about the established methods of staying healthy as we grow older. Then, with the help of researchers Dr. Aubrey De Grey and Dr. Judith Campisi, we explore the cutting edge technologies that might play a role in extending human lifespan. https://www.livingto100.com/2019-07-2931 minRejuvenation Roundup PodcastRejuvenation Roundup PodcastRejuvenation Roundup - March 2019Explore the latest updates in longevity research and anti-aging science in the March 2019 edition of the Rejuvenation Roundup Podcast, hosted by Ryan O'Shea of Future Grind! This episode features interviews with Dr. Aubrey de Grey, Dr. Judith Campisi, Dr. Kelsey Moody, & more! More at lifespan.io/roundup.2019-03-3024 minBrisante Themen in der Diskussionssendung Ansichtssache - PodcastBrisante Themen in der Diskussionssendung Ansichtssache - PodcastAnsichtssache "Die Bibel: Wort Gottes? Großartige Literatur? Irreführung?", mit Judith Bertagnolli - 29-12-2018Die Bibel: Das Buch der Bücher fasziniert, ist voller Poesie und Grausamkeiten, ist Streitpunkt, Quelle des Glaubens- und vor allem Auslegungssache. Die Bibel- eine Irreführung? Großartige Literatur? Wort Gottes? Gäste bei der Ansichtssache sind Pastor Michael Jäger, Don Mario Gretter, die Bibelwissenschaftlerin Maria Theresia Ploner und der evanglikale Christ Daniel Campisi.2018-12-2900 minFutureTech PodcastFutureTech PodcastDr. Judith Campisi of the Buck Institute Discusses Cell Senescence, Aging, and Quality of LifeShe explains how chronic inflammation is a double-edged sword and that research has uncovered surprising results on mice and how cell senescence impacts their existence. Studies have found that exercise and diet may benefit cell senescence in mice; it’s thought provoking even as the process is not fully understood. Finally, she gives a prediction on the expected lifespan of humans two or three decades from now. Is it even possible to increase it? And if so, how? Dr. Campisi also discusses: Why humans are impacted by cell senescence now more than ever in...2018-10-1933 minhumanOS RadiohumanOS Radio#025 - How to Clear Senescent Cells to Stay Healthier as we Age - Judith Campisi, PhDWhy is that we tend to see many diseases of aging occur around the same time in life? One reason is that we accumulate senescent cells with age, and these cells promote the aging process. There is, however, exciting new research that shows how these cells can be cleared as we age. Some of the compounds are drugs but others are natural compounds that could have a meaningful effect.In this episode, Dan speaks with an expert on the subject: Judith Campisi, Ph.D., from the Buck Institute of Aging in Marin County, California.2017-08-0124 minhumanOS RadiohumanOS RadioHow to clear senescent cells to stay healthier as we age (Judith Campisi, PhD, Buck Institute)Why is that we tend to see many diseases of aging occur around the same time in life? One reason is that we accumulate senescent cells with age, and these cells promote the aging process. There is, however, exciting new research that shows how these cells can be cleared as we age. Some of the compounds are drugs but others are natural compounds that could have a meaningful effect. In this episode, I speak with an expert on the subject: Judith Campisi, Ph.D., from the Buck Institute of Aging in Marin County, California.2017-08-0124 minhumanOS RadiohumanOS Radio#025 - How to Clear Senescent Cells to Stay Healthier as we Age - Judith Campisi, PhDWhy is that we tend to see many diseases of aging occur around the same time in life? One reason is that we accumulate senescent cells with age, and these cells promote the aging process. There is, however, exciting new research that shows how these cells can be cleared as we age. Some of the compounds are drugs but others are natural compounds that could have a meaningful effect. In this episode, Dan speaks with an expert on the subject: Judith Campisi, Ph.D., from the Buck Institute of Aging in Marin County, California.2017-08-0100 minFoundMyFitnessFoundMyFitness#036 Judith Campisi, Ph.D. on Cellular Senescence, Mitochondrial Dysfunction, Cancer & AgingDr. Judith Campisi is a professor of biogerentology at the Buck Institute for Research on Aging and a co-editor in chief of the Aging Journal. As an expert on cellular senescence, the discussion involves a lot of talk about aging and cancer, where senescence plays a very important fundamental role. What are some of the strategies we might use in the future to prevent senescent cells? What causes them in the first place?  In this episode, you’ll discover:  (00:00) Introduction (05:12) Fundamental molecular and cellular processes of aging (13:19) What is senescence and why did we evolve t...2017-04-281h 08Futures in Biotech (Audio)Futures in Biotech (Audio)Cancer and Aging: Rival Demons with Dr. Judith Campisi - Seeking to better understand how cellular senescence contributes to the pathophysiology of aging. Dr. Judith Campisi's scientific investigations are at the nexus between cancer and aging. She seeks to better understand how cellular senescence contributes to the pathophysiology of aging. Host: Marc Pelletier Guests: Simon Melov, PhD and Dr. Judith Campisi, Ph.D. Sponsored by: Synergy 1. Thanks to Phil Pelletier and Will Hall for the great themes. Thanks to CacheFly for providing the bandwidth for this netcast. 2011-01-1459 minFutures in Biotech (Video)Futures in Biotech (Video)Cancer and Aging: Rival Demons with Dr. Judith Campisi - Seeking to better understand how cellular senescence contributes to the pathophysiology of aging. Dr. Judith Campisi's scientific investigations are at the nexus between cancer and aging. She seeks to better understand how cellular senescence contributes to the pathophysiology of aging. Host: Marc Pelletier Guests: Simon Melov, PhD and Dr. Judith Campisi, Ph.D. Sponsored by: Synergy 1. We invite you to read, add to, and amend our show notes. Comments and suggestions on Futures in Biotech. Also thanks to Phil Pelletier and Will Hall for the great themes. Thanks to CacheFly for providing the bandwidth for this netcast. 2011-01-1459 min