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DASON DigestDASON DigestAre You Ready for It? Assessing Cephalosporin Allergies with the CEPH-FAST ScoreEpisode Notes In this episode, DASON Clinical Pharmacist Liaison Dr. Melissa Johnson talks with Dr. Jason Trubiano, Director of Infectious Diseases at Austin Health in Australia. Drs. Johnson and Trubiano discuss an article in Journal of Infection entitled "Development and validation of a cephalosporin allergy clinical decision rule." The article can be found here: https://pubmed.ncbi.nlm.nih.gov/40288499/ For more information about DASON, please visit: https://dason.medicine.duke.edu/2025-05-3024 minDASON DigestDASON Digest(Re)moving the needle: implementation of an institutional IV to PO treatment guidance for bone and joint infectionsJoin DASON Clinical Pharmacist Liaison Dr. Jeannette Bouchard as she reviews the recent article published in Antimicrobial Stewardship & Healthcare Epidemiology titled: “(Re)Moving the Needle: A Retrospective, Quasi-Experimental Assessment of the Impact of a Treatment Guideline on Oral Antibiotic Prescribing for Orthopedic Infections." She discusses how this study highlights the real-world impact of guideline implementation on shifting antibiotic prescribing practices for bone and joint infections. The article reviewed in this episode can be found here: https://pubmed.ncbi.nlm.nih.gov/40160226/ For more information about DASON, please visit: https://dason.medicine.duke.edu/2025-05-1609 minDASON DigestDASON DigestSole Support: Using Clinical Decision Support Solutions to Improve Care for Patients Inpatients with Diabetic Foot InfectionsIn this episode, DASON Clinical Pharmacist Liaison Dr. April Dyer talks with us about how a microbiology-driven electronic health record-algorithm and order set can decrease antipseudomonal use in diabetic foot infections. The article reviewed in this episode can be found here: https://pubmed.ncbi.nlm.nih.gov/40160223/ For more information about DASON, please visit: https://dason.medicine.duke.edu/2025-05-0211 minDASON DigestDASON DigestSBP Prophylaxis: What We’re Doing, Why We’re Doing It… and Should We Keep Doing It?Episode Notes In this episode, DASON Clinical Pharmacist Liaison Dr. Angelina Davis chats with us about several articles about antibiotic prophylaxis for spontaneous bacterial peritonitis (SBP) in patients with cirrhosis. The materials reviewed in this episode can be found on the DASON Digest page on our website: https://dason.medicine.duke.edu/blog/sbp-prophylaxis-what-were-doing-why-were-doing-it-and-should-we-keep-doing-it For more information about DASON, please visit: https://dason.medicine.duke.edu/2025-04-1821 minDASON DigestDASON DigestShort and Sweet: Is short course appropriate for uncomplicated Streptococcal bacteremia?Episode Notes Join the Duke ID PGY2 resident Natalie Harris as she talks with Dr. Julie Gray about her new article published in ASHE this year titled “Short versus long treatment duration for streptococcal bloodstream infection." The article reviewed in this episode can be found here: https://pubmed.ncbi.nlm.nih.gov/40026772/ for more information about DASON, please visit: https://dason.medicine.duke.edu/2025-04-0420 minDASON DigestDASON DigestGuideline-Driven Success: Standardizing Care for Gram-Negative Bloodstream InfectionsEpisode Notes Join DASON liaison Jeannette Bouchard as she talks with Dr. Kati Shihadeh about her new article published in ASHE this year titled “Standardization in the management of gram-negative bloodstream infections after implementation of a clinical care guideline at a large academic, safety-net institution: a quasi-experimental study. The article reviewed in this episode can be found here: https://pmc.ncbi.nlm.nih.gov/articles/PMC11822621/ For more information about DASON, please visit: https://dason.medicine.duke.edu/2025-03-2123 minDASON DigestDASON DigestLess is More-Dazole? Metronidazole twice daily versus three times daily for B. fragilis bacteremiaEpisode Notes In this episode, DASON Clinical Pharmacist Liaison Dr. Melissa Johnson chats with Dr. Sunish Shah from University of Pittsburgh Medical Center about metronidazole dosing for bloodstream infections. The article reviewed in the episode can be found here: https://pubmed.ncbi.nlm.nih.gov/39667533/ For more information about DASON, please visit: https://dason.medicine.duke.edu/2025-02-2134 minDASON DigestDASON DigestAntibiotic De-escalation in Sepsis PatientsEpisode Notes In this episode DASON Clinical Pharmacist Liaison Dr. April Dyer talks with Dr. Rebekah Moehring talk to us about outcomes of antibiotic de-escalation in patients with suspected sepsis. The article discussed in the episode can be viewed here: https://pubmed.ncbi.nlm.nih.gov/39657050/ For more information about DASON, please visit: https://dason.medicine.duke.edu/2025-02-0726 minDASON DigestDASON DigestTesting Troubles: Navigating C. difficile confusionEpisode Notes Join Drs. Libby Dodds Ashley and Dev Anderson as they discuss one of the latest articles from the Duke ID team regarding C. difficile testing and the confusion that surrounds certain testing results. The articles reviewed in this episode can be found here: https://pubmed.ncbi.nlm.nih.gov/39828613/ and https://pubmed.ncbi.nlm.nih.gov/39180325/ For more information about DASON, please visit: https://dason.medicine.duke.edu/2025-01-2422 minDASON DigestDASON DigestThe BALANCE Trial: 7 vs 14 Days for Bloodstream InfectionIn this episode of the DASON Digest Podcast, Dr. Angelina Davis, one of our DASON Clinical Pharmacist Liaisons, talks to us about the BALANCE Trial and the work the investigators did with duration of antibiotic treatment for bloodstream infections in hospitalized patients. The article reviewed in this episode can be found here: https://pubmed.ncbi.nlm.nih.gov/39565030/ For more information about DASON, please visit: https://dason.medicine.duke.edu/2025-01-1013 minDASON DigestDASON DigestDecoding DxEx: the CDC Core Elements of Hospital Diagnostic ExcellenceEpisode Notes In this episode, DASON Clinical Pharmacist Liaison Dr. Melissa Johnson talks with Dr. Dan Morgan from University of Maryland School of Medicine. The articles and documents reviewed can be found here: https://www.cdc.gov/patient-safety/hcp/hospital-dx-excellence/index.html https://www.cdc.gov/patient-safety/media/pdfs/DxEx-Tool-Priority-Examples-508.pdf https://www.cdc.gov/patient-safety/media/pdfs/DxEx-Tool-Additional-Examples-508.pdf https://www.cdc.gov/patient-safety/media/pdfs/DxEx-Tool-Medical-Test-Checklist-508.pdf https://pubmed.ncbi.nlm.nih.gov/36786646/ https://pubmed.ncbi.nlm.nih.gov/39602334/ For more information about DASON, please visit: https://dason.medicine.duke.edu/2024-12-0645 minDASON DigestDASON DigestEpisode 100: A Celebration of StewardshipEpisode Notes In this very special episode we have guest appearances from old and new stewardship friends. References for this episode can be found at this link: https://dason.medicine.duke.edu/blog/episode-100-celebration-stewardship For more information about DASON, please visit: https://dason.medicine.duke.edu2024-11-2258 minDASON DigestDASON DigestUnexpected Findings: Ertapenem in Surgical ProphylaxisEpisode Notes For this episode, Dr. Libby Dodds Ashley is joined by Dr. Chris Hostler to discuss Dr. Hostler’s recent article evaluating postoperative outcomes in patients receiving ertapenem for colon surgery. This article that includes some data from our DASON sites so this is a MUST listen! The article reviewed in this episode can be found here: https://pubmed.ncbi.nlm.nih.gov/39363596/ For more information about DASON, please visit: https://dason.medicine.duke.edu/2024-11-0815 minDASON DigestDASON DigestA Multicenter Retrospective Study Evaluating Intravenous to Oral Antibiotic Stepdown for Uncomplicated Streptococcal BacteremiaEpisode Notes In this episode of the DASON Digest podcast, DASON Clinical Pharmacist Liaison Dr. Melissa Johnson reviews an article that compares the efficacy and safety of intravenous (IV) versus oral (PO) stepdown therapy for uncomplicated streptococcal bacteremia. The article can be found here: https://academic.oup.com/ofid/article/11/7/ofae361/7701251 For more information about DASON, please visit: https://dason.medicine.duke.edu/2024-10-1126 minDASON DigestDASON DigestRethinking Daptomycin Dosing: New data on fixed dose daptomycinEpisode Notes Join DASON Clinical Pharmacist Dr. Libby Dodds Ashley as she discusses a recent article in Pharmacotherapy on daptomycin dosing with one of the primary authors, Dr. Katie Olney. The article reviewed in this episode can be found here: https://pubmed.ncbi.nlm.nih.gov/39078247/ For more information about DASON, please visit: https://dason.medicine.duke.edu/2024-08-3018 minDASON DigestDASON DigestReturn of the Penicillin Allergy LabelEpisode Notes In this exciting episode, DASON Clinical Pharmacist Dr. April Dyer discusses a hot off the press article that follows up the results from the big PALACE trial that was published in 2023. The article reviewed in this episode can be found here: https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2822413 For more information about DASON, please visit: https://dason.medicine.duke.edu/2024-08-2012 minDASON DigestDASON DigestIs ID the Consult of Fear?Episode Notes In this episode, DASON Clinical Pharmacist Liaison Dr. April Dyer walks us through an article from Clinical Infectious Diseases entitled "Beyond Infection: Mortality and End-of-Life Care Associated with Infectious Disease Consultation in an Academic Health System." The article reviewed in this episode can be found here: https://pubmed.ncbi.nlm.nih.gov/38867715/ For more information about DASON, please visit: https://dason.medicine.duke.edu/2024-07-1918 minDASON DigestDASON DigestIt Goes On and On and On: Reviewing the new RCT for Continuous infusion vs. Intermittent infusion Beta-lactamsIn this exciting episode, Drs. Libby Dodds Ashley and Jeannette Bouchard are joined by Dr. Jason Roberts to discuss his two newly published articles in JAMA that help to answer the question: is there a difference between continuous and intermittent infusions of beta-lactam antibiotics, especially in the critically ill populations? The reviewed materials can be found here: https://dason.medicine.duke.edu/blog/it-goes-and-and-reviewing-new-rct-continuous-infusion-vs-intermittent-infusion-beta-lactams For more information about DASON, please visit: https://dason.medicine.duke.edu/2024-06-2131 minDASON DigestDASON DigestPEN-FAST and Furious: The efficacy of the PEN-FAST tool in de-labeling previously reported penicillin allergiesEpisode Notes In this episode, University of Kentucky PGY2 Infectious Diseases Pharmacy Residents, Will Harris and Tyler Pitcock, discuss the recently published article evaluating the efficacy of the clinical decision tool, PEN-FAST, in de-labeling patients with reported penicillin allergies with one of the authors and Duke University Hospital Infectious Diseases Physicians, Dr. Nick Turner. The article reviewed in this episode can be found here: https://pubmed.ncbi.nlm.nih.gov/37459086/ For more information about DASON, please visit: https://dason.medicine.duke.edu/2024-04-2626 minDASON DigestDASON DigestThe devil's in the defaults: the impact of eliminating default durations of therapyEpisode Notes In this episode, Duke University Hospital Infectious Diseases Pharmacist Dr. Rebekah Wrenn and her resident, Amy Mackowiak, review Dr. Wrenn's recently published article evaluating the impact of default duration elimination on exposure to fluoroquinolone therapy.  The article reviewed in today's episode can be found here: https://pubmed.ncbi.nlm.nih.gov/38347810/ For more information about DASON, please visit: https://dason.medicine.duke.edu/2024-04-1227 minDASON DigestDASON DigestNavigating the LAByrinth: Updates in Antibacterial Susceptibility TestingEpisode Notes In this episode of the DASON Digest Podcast, one of our DASON Clinical Pharmacist Liaisons, Dr. Melissa Johnson, talks with Dr. Jim Lewis, ID Clinical Pharmacy Coordinator and Adjunct Associate Professor at Oregon Health & Science University Departments of Pharmacy and ID in Portland, Oregon. The material reviewed in today's podcast can be found here: https://clsi.org/standards/products/microbiology/documents/m100/ For more information about DASON, please visit: https://dason.medicine.duke.edu2024-04-0553 minDASON DigestDASON DigestIncorporating Adverse Event Feedback Into Antibiotic StewardshipEpisode Notes In this episode of the DASON Digest podcast, DASON Clinical Pharmacist Liaison Dr. April Dyer talks to us about how to incorporate adverse event feedback into antibiotic stewardship. The article reviewed in this episode can be found here: https://pubmed.ncbi.nlm.nih.gov/38415083/ For more information about DASON, please visit: https://dason.medicine.duke.edu2024-03-1514 minDASON DigestDASON DigestOptimizing the use of the GI Panel and strategies to improve appropriate testingEpisode Notes In this episode, DASON Clinical Pharmacist Liaisons Drs. Jeannette Bouchard and Libby Dodds-Ashley walk us through the details of a recent article published in ASHE to assess the impact of a clinical decision support survey to improve GI Panel ordering appropriateness at a VA. The article reviewed in this episode can be found here: https://pubmed.ncbi.nlm.nih.gov/38415090/ For more information about DASON, please visit: https://dason.medicine.duke.edu/2024-03-0118 minDASON DigestDASON DigestWhich of Active vs Passive Response to Rapid Diagnostic Blood Culture ResultsEpisode Notes In this episode of the DASON Digest podcast, DASON Clinical Pharmacist Liaison Dr. Angelina Davis talks to us about the use of active versus passive methods of responding to rapid diagnostic blood culture results. The article reviewed can be found here: https://pubmed.ncbi.nlm.nih.gov/36483427/ For more information about DASON, please visit: https://dason.medicine.duke.edu/2024-02-1914 minDASON DigestDASON DigestExploring the Microbiome: Pertinent details from a phase 1 study exploring omadacycline in healthy gutsEpisode Notes In this episode, DASON Clinical Pharmacist Liaison Dr. Jeannette Bouchard is joined by Dr. Kevin Garey, an adjunct professor at the University of Texas School of Public Health and senior author of the reviewed article. They walk us through the details of the microbiome effects oral omadacycline has versus oral vancomycin and what this might mean for the future of the treatment for C. difficile infections. The materials reviewed in today's episode can be found here: https://pubmed.ncbi.nlm.nih.gov/38051631/ and https://pubmed.ncbi.nlm.nih.gov/22563022/ For more information about...2024-02-0223 minDASON DigestDASON DigestIt’s All in the Dose: High-dose oral beta-lactams for bacteremic UTIs due to EnterobacteralesEpisode Notes In this episode, DASON Clinical Pharmacist Liaisons Drs. Melissa Johnson and Jeannette Bouchard discuss an article from ASHE on high-dose oral beta-lactam definitive therapy compared to fluoroquinolone or trimethoprim-sulfamethoxazole oral therapy for bacteremia secondary to a urinary tract infection. The article reviewed can be found here: https://pubmed.ncbi.nlm.nih.gov/37771747/ For more information about DSAON, please visit: https://dason.medicine.duke.edu/2024-01-1919 minDASON DigestDASON DigestSource Specific Sepsis Order Sets Lead to Improved Empiric Therapy in the EDEpisode Notes In this episode, Dr. April Dyer, one of our DASON Clinical Pharmacist Liaisons, talks to us about source specific order sets leading to improved empiric therapy in the ED in a 200 bed hospital. The article reviewed in this episode can be found here: https://academic.oup.com/ofid/advance-article/doi/10.1093/ofid/ofad677/7491622# To learn more about DASON, please visit: https://dason.medicine.duke.edu2024-01-0510 minDASON DigestDASON DigestOptimizing Outpatient OrderingEpisode Notes In this episode, Drs. Bouchard, Dodds Ashley, and Perez review a large study tackling inappropriate antimicrobial use in the outpatient setting. The article reviewed in this episode can be found here: https://academic.oup.com/ofid/advance-article/doi/10.1093/ofid/ofad585/7439469 For more information about DASON, please visit: https://dason.medicine.duke.edu2023-12-1529 minDASON DigestDASON DigestEnding VAP: is vaporizing antibiotics the answer?Episode Notes In this episode, Drs. Libby Dodds Ashley and Jeannette Bouchard, two of our DASON Clinical Pharmacists, talk to us about bringing and end to VAP. The article reviewed in this episode can be found here: https://pubmed.ncbi.nlm.nih.gov/37888914/ For more information about DASON, please visit: https://dason.medicine.duke.edu2023-12-0120 minDASON DigestDASON DigestNeurotoxicity vs Nephrotoxicity: A Look at the Comparative Safety of Cefepime and Piperacillin-Tazobactam in Adults Hospitalized With Acute InfectionEpisode Notes In this episode, Dr. April Dyer, one of the DASON Clinical Pharmacists, talks about cefepime vs piperacillin-tazobactam in adults hospitalized with acute infection. The article reviewed in this episode can be found here: https://pubmed.ncbi.nlm.nih.gov/37837651/ For more information about DASON, please visit: https://dason.medicine.duke.edu2023-11-0321 minDASON DigestDASON DigestAnalyzing Antibiograms: Reassessing a major toolEpisode Notes Drs. Perez, Hillenbrand and Mourad do a deep dive on how to best apply one of our most common stewardship tools. The article reviewed in this episode can be found here: https://academic.oup.com/cid/advance-article/doi/10.1093/cid/ciad467/7240295 For more information about DASON, please visit: https://dason.medicine.duke.edu2023-10-2034 minDASON DigestDASON DigestHit me with your best shot! Tools to select the best empiric therapy in complicated UTIsEpisode Notes In this episode of the DASON Digest Podcast, DASON Clinical Pharmacist Liaison Dr. Jeannette Bouchard talks to us about clinical risk scores to improve empiric antimicrobial selection for outpatient complicated urinary tract infections. The article reviewed in this episode can be found here: https://academic.oup.com/ofid/article/10/8/ofad319/7198038#413122181 For more information about DASON, please visit: https://dason.medicine.duke.edu2023-09-2918 minDASON DigestDASON DigestCan we FINALLY stop antibiotics in culture negative serious infections?Episode Notes In this episode of the DASON Digest Podcast, DASON Clinical Pharmacist Liaison Dr. Angelina Davis talks to us about the early discontinuation of antibiotics in patients admitted with clinically suspected serious infection but negative cultures. The article reviewed in this episode can be found here: https://pubmed.ncbi.nlm.nih.gov/37449298/ For more information about DASON, please visit: https://dason.medicine.duke.edu2023-09-0120 minDASON DigestDASON DigestCreating Impactful, Feasible, Actionable, and Measurable Stewardship InterventionsEpisode Notes In this episode of the DASON Digest Podcast, DASON Clinical Pharmacist Liaison Dr. April Dyer talks to us about improving the efficiency of antimicrobial stewardship action in acute care facilities. The article reviewed in this episode can be found here: https://academic.oup.com/ofid/advance-article/doi/10.1093/ofid/ofad412/7234482 For more information about DASON, please visit: https://dason.medicine.duke.edu2023-08-1818 minDASON DigestDASON DigestDon’t be so Negative! A Look at GN-BSI in the USEpisode Notes Dr. Rey Perez chats with our newest DASON Clinical Pharmacist Liaison, Dr. Jeannette Bouchard, about the epidemiology of gram negative blood stream infections. The article reviewed in this episode can be found here: https://academic.oup.com/ofid/article/10/7/ofad265/7175984 For more information about DASON, please visit: https://dason.medicine.duke.edu2023-08-0427 minDASON DigestDASON DigestRx for Success: Tackling Penicillin Allergy De-Labelling in our HospitalsEpisode Notes Dr. Melissa Johnson from DASON talks to us about removing incorrect penicillin allergy labels. There are lots of supplemental materials for this episode, and they can all be viewed on the episode's page on our website: https://dason.medicine.duke.edu/blog/rx-success-tackling-penicillin-allergy-de-labelling-our-hospitals The main article discussed today is: https://pubmed.ncbi.nlm.nih.gov/37354996/ For more information about DASON, please visit: https://dason.medicine.duke.edu/2023-07-2116 minDASON DigestDASON DigestSSI Compendium UpdateEpisode Notes In this episode, Infectious Diseases fellow Dr. Rey Perez chats with DCASIP Executive Director Dr. Dev Anderson about the latest surgical site infection compendium updates. The article reviewed can be found here: https://www.cambridge.org/core/journals/infection-control-and-hospital-epidemiology/article/strategies-to-prevent-surgical-site-infections-in-acutecare-hospitals-2022-update/2F824B9ADD6066B29F89C8A2A127A9DC To learn more about DASON, please visit: https://dason.medicine.duke.edu/2023-06-0934 minDASON DigestDASON DigestAntibiotic Spectrum ScoresEpisode Notes This episode features Dr. April Dyer from DASON. The article reviewed in the episode can be found here: https://pubmed.ncbi.nlm.nih.gov/36999909/ For more information about DASON, please visit: https://dason.medicine.duke.edu2023-05-2618 minDASON DigestDASON DigestPip-Tazo: A Pancreatic Panacea?Episode Notes This Episode features Drs. Shaefer Spires and Rey Perez from DASON. The article reviewed in this episode is available here: https://jamanetwork.com/journals/jama/fullarticle/2804245. JAMA. 2023;329(18):1579-1588. doi:10.1001/jama.2023.5728 For more information about DASON please visit: https://dason.medicine.duke.edu Find out more at https://dason-digest.pinecast.co2023-05-1231 minDASON DigestDASON DigestAntimicrobial susceptibility testing: An updated primer for clinicians in the era of antimicrobial resistance: Insights from the Society of Infectious Diseases PharmacistsEpisode Notes This month, University of Kentucky HealthCare PGY2 Infectious Diseases Pharmacy Residents Becca and Kam are on their DASON rotation and are talking to DASON Digest listeners about antimicrobial susceptibility testing. The article reviewed in the episode is available here: https://pubmed.ncbi.nlm.nih.gov/36825480/ For more information about DASON, please visit: https://dason.medicine.duke.edu/2023-04-2826 minDASON DigestDASON DigestHydrocortisone in Severe Community-Acquired PneumoniaEpisode Notes This month, University of Kentucky HealthCare PGY2 Infectious Diseases Pharmacy Residents Becca and Kam are on their DASON rotation and are talking to DASON Digest listeners about Hydrocortisone use in severe CAP. The article reviewed in this episode is available here: https://pubmed.ncbi.nlm.nih.gov/36942789/ For more information about DASON, please visit: https://dason.medicine.duke.edu/2023-04-1426 minDASON DigestDASON DigestProphylaxis Progress ReportEpisode Notes This episode features Drs. Libby Dodds Ashley and Rey Perez from DASON. The article reviewed in this episode is available here: https://pubmed.ncbi.nlm.nih.gov/36774539/ For more information about DASON, please visit: https://dason.medicine.duke.edu/2023-03-3127 minDASON DigestDASON DigestRSV vaccines coming: Its ok to be excitedEpisode Notes This episode features Dr. Shaefer Spires, DASON Medical Director, and Dr. Ethan Brenneman, PGY2 Infectious Diseases Pharmacy Resident for Duke University Hospital. The documents reviewed in this episode are: https://duke.box.com/s/7zvupbr81euvcujzq20jbpbj0yuqnafy and https://duke.box.com/s/738zmcuz4voh2urm1j0o3v2i540ziczp For more information about DASON, please visit: https://dason.medicine.duke.edu Find out more at https://dason-digest.pinecast.co2023-03-1724 minDASON DigestDASON DigestA Guide to Diagnostic StewardshipEpisode Notes This episode features Dr. Angelina Davis from DASON. The article reviewed in this episode is available here: https://pubmed.ncbi.nlm.nih.gov/36786646/ For more information about DASON, please visit: https://dason.medicine.duke.edu Find out more at https://dason-digest.pinecast.co2023-03-0311 minDASON DigestDASON DigestLet's take a mindful pause before treating bacteriuria in older adultsEpisode Notes This episode features Dr. April Dyer from DASON. The article reviewed in this episode is available here: https://pubmed.ncbi.nlm.nih.gov/36714291/ For more information about DASON, please visit: https://dason.medicine.duke.edu Find out more at https://dason-digest.pinecast.co2023-02-1711 minDASON DigestDASON DigestDiscordant C. diff testing results - to treat or not to treat?Episode Notes This episode features Drs. Shaefer Spires and Rey Perez from DASON. The article reviewed in this episode is available here: https://pubmed.ncbi.nlm.nih.gov/34325761/ For more information about DASON, please visit: https://dason.medicine.duke.edu/ Find out more at https://dason-digest.pinecast.co2023-02-0317 minDASON DigestDASON DigestStewardship Secrets: Optimizing carbapenem use in our facilitiesEpisode Notes This episode features Dr. Melissa Johnson from DASON. The article reviewed in this episode is available here: https://pubmed.ncbi.nlm.nih.gov/36601545/ For more information about DASON, please visit: https://dason.medicine.duke.edu Find out more at https://dason-digest.pinecast.co2023-01-2009 minDASON DigestDASON DigestSpellcheck Stewardship: A Happy Holidays from DASONEpisode Notes This episode features Dr. Libby Dodds Ashley from DASON and Dr. Rey Perez, our current Duke ID Fellow. Libby and Rey talk about some upcoming changes to the podcast, as well as discuss the following article: https://doi.org/10.1136/bmj.o2946 For more information about DASON, please visit: https://dason.medicine.duke.edu Find out more at https://dason-digest.pinecast.co2023-01-0614 minDASON DigestDASON DigestA Decade of Fluoroquinolone StewardshipThis episode features Dr. April Dyer from DASON. The article reviewed in this episode is available here: https://doi.org/10.1017/ash.2022.326.  For more information about DASON, please visit: https://dason.medicine.duke.edu. Find out more at https://dason-digest.pinecast.co2022-12-0909 minDASON DigestDASON DigestReview of the CDC's Antibiotic Use Report - 2022This episode features Dr. Travis Jones from DASON. The CDC report reviewed in this episode is available here: https://www.cdc.gov/antibiotic-use/stewardship-report/current.html. For more information about DASON, please visit: https://dason.medicine.duke.edu. Find out more at https://dason-digest.pinecast.co2022-11-2417 minDASON DigestDASON DigestStreptococcal Bacteremia and the Risk of Infective EndocarditisThis episode features Dr. Shaefer Spires from DASON and Dr. Reinaldo (Rey) Perez from Duke Infectious Diseases. The article reviewed in this episode is available here: https://doi.org/10.1186/s12879-021-06391-2.  For more information about DASON, please visit: https://dason.medicine.duke.edu. Find out more at https://dason-digest.pinecast.co2022-11-1118 minDASON DigestDASON DigestStewardship Practices at US HospitalsThis episode features Dr. Melissa Johnson from DASON. The article reviewed in this episode is available here: https://doi.org/10.1017/ice.2022.241. For more information about DASON, please visit: https://dason.medicine.duke.edu.   Find out more at https://dason-digest.pinecast.co2022-10-2817 minDASON DigestDASON DigestThe DETOURS Study - A Chat with the AuthorThis episode features Dr. Libby Dodds Ashley and Dr. Rebekah Moehring from DASON. The article discussed in this episode is available here: https://doi.org/10.1093/cid/ciac787. For more information about DASON, please visit: https://dason.medicine.duke.edu. Find out more at https://dason-digest.pinecast.co2022-10-1400 minDASON DigestDASON DigestA Novel Metric to Measure Antibiotic Use and Spectrum of ActivityThis episode features Dr. Angelina Davis from DASON. The article reviewed in this episode is available here: https://doi.org/10.1093/cid/ciab1034. For more information about DASON, please visit: https://dason.medicine.duke.edu. Find out more at https://dason-digest.pinecast.co2022-09-3018 minDASON DigestDASON DigestSSI Rates Among Patients Receiving Elective Colorectal Surgery with Beta-Lactam vs. Non-Beta-Lactam-Based Antimicrobial ProphylaxisThis episode features Dr. April Dyer from DASON. The article discussed in this episode is available here: https://doi.org/10.1017/ice.2022.192. For more information about DASON, please visit: https://dason.medicine.duke.edu. Find out more at https://dason-digest.pinecast.co2022-09-0914 minDASON DigestDASON DigestLet's Talk About Surgical ProphylaxisThis episode features Dr. Travis Jones from DASON. The article discussed in this episode is available here: https://doi.org/10.1001/jamasurg.2019.0569. For more information about DASON, please visit: https://dason.medicine.duke.edu. Find out more at https://dason-digest.pinecast.co2022-08-2616 minDASON DigestDASON DigestAntibiotic Effects on the Gut Microbiome & Resistome: It’s Worse than We Thought - An Interview with Dr. Jennie KwonThis episode features Dr. Shaefer Spires from DASON and Dr. Jennie Kwon from Washington University School of Medicine. The article discussed in this episode is available here: https://doi.org/10.1016/j.celrep.2022.110649. For more information about DASON, please visit: https://dason.medicine.duke.edu. Find out more at https://dason-digest.pinecast.co2022-08-1216 minDASON DigestDASON DigestLess is More: Reducing Unnecessary Antibiotic Use for Asymptomatic BacteriuriaThis episode features Dr. Melissa Johnson from DASON. The article reviewed in this episode is available here: https://pubmed.ncbi.nlm.nih.gov/35877123/. For more information about DASON, please visit: https://dason.medicine.duke.edu. Find out more at https://dason-digest.pinecast.co2022-07-2914 minDASON DigestDASON DigestA Chat With the Author: Network- and Health System-guided StewardshipThis episode features Dr. Libby Dodds Ashley from DASON and Dr. Whitney Buckel from Intermountain Healthcare. The article reviewed in this episode is available here: https://doi.org/10.1093/cid/ciac515. For more information about DASON, please visit: https://dason.medicine.duke.edu. Find out more at https://dason-digest.pinecast.co2022-07-1516 minDASON DigestDASON DigestAntibiotic Overuse and Stewardship at Hospital DischargeThis episode features Dr. Angelina Davis from DASON. The article reviewed in this episode is available here: https://doi.org/10.1093/cid/ciab842. For more information about DASON, please visit: https://dason.medicine.duke.edu. Find out more at https://dason-digest.pinecast.co2022-07-0128 minDASON DigestDASON DigestReducing Antibiotic Use for Upper Respiratory Infections in OutpatientsThis episode features Dr. April Dyer from DASON. The article reviewed in this episode is available here: https://doi.org/10.1017/ice.2022.83. For more information about DASON, please visit: https://dason.medicine.duke.edu. Find out more at https://dason-digest.pinecast.co2022-06-1715 minDASON DigestDASON DigestStewardship Opportunities Upon Hospital DischargeThis episode features Dr. Travis Jones from DASON. The article reviewed in this episode is available here: https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2792123. For more information about DASON, please visit: https://dason.medicine.duke.edu. Find out more at https://dason-digest.pinecast.co2022-06-0316 minDASON DigestDASON DigestIf you have to: Non-antibiotic prophylactic treatment for recurrent UTIThis episode features Dr. Shaefer Spires from DASON. The article reviewed in this episode is available here: https://doi.org/10.1136/bmj-2021-0068229. For more information about DASON, please visit: https://dason.medicine.duke.edu.2022-05-2021 minDASON DigestDASON DigestOutpatient Stewardship for UTIs: Reducing Fluoroquinolone UseThis episode features Dr. Melissa Johnson from DASON. The article reviewed in this episode is available here: https://pubmed.ncbi.nlm.nih.gov/35403600/. For more information about DASON, please visit: https://dason.medicine.duke.edu.2022-05-0609 minDASON DigestDASON DigestAntibiograms for Escalation: What’s the Application?This episode features Drs. Jenni Thomas and Wes Johnson from University of Kentucky Healthcare. The article reviewed in this episode is available here: https://doi.org/10.1093/cid/ciac256. For more information about DASON, please visit: https://dason.medicine.duke.edu.2022-04-2227 minDASON DigestDASON DigestThe Waiting Game: Time Between Blood Culture SetsThis episode features Drs. Jenni Thomas and Wes Johnson from University of Kentucky Healthcare. The articles reviewed in this episode are available here: https://doi.org/10.1017/ash.2022.27 https://doi.org/10.1128/jcm.01005-21 For more information about DASON, please visit: https://dason.medicine.duke.edu.2022-04-0824 minDASON DigestDASON DigestThe Role of the Antimicrobial Stewardship Program in Pandemic ResponseThis episode features Dr. April Dyer from DASON. The article reviewed in this episode is available here: https://doi.org/10.1017/ash.2022.34. For more information about DASON, please visit: https://dason.medicine.duke.edu.2022-03-2513 minDASON DigestDASON DigestOral Cephalosporins vs First-line Agents for Outpatients with PyelonephritisThis episode features Dr. Travis Jones from DASON. The article reviewed in this episode is available here: https://doi.org/10.1016/j.ijantimicag.2022.106560. For more information about DASON, please visit: https://dason.medicine.duke.edu.2022-03-1113 minDASON DigestDASON DigestVancomycin Monitoring: Are We Below the Curve? A Discussion with ExpertsThis episode features Dr. Shaefer Spires from DASON and Drs. Katie Olney and Katie Wallace from University of Kentucky Healthcare. The article reviewed in this episode is available here: https://doi.org/10.1002/phar.2670. For more information about DASON, please visit: https://dason.medicine.duke.edu.2022-02-2534 minDASON DigestDASON DigestSystems Say Go: Assessing Antibiotic Prescribing After Removal of a Penicillin Allergy AlertThis episode features Dr. Melissa Johnson from DASON. The articles reviewed in this episode are available using the following links: https://doi.org/10.1001/jamanetworkopen.2021.8367 https://doi.org/10.1016/j.jaip.2021.06.059 For more information about DASON, please visit: https://dason.medicine.duke.edu.2022-02-1113 minDASON DigestDASON DigestEngaging Nurse StewardsThis episode features Dr. Libby Dodds Ashley from DASON. The articles reviewed in this episode are available here: https://doi.org/10.1017/ash.2021.216 https://doi.org/10.1017/ice.2018.362 https://doi.org/10.1016/S0140-6736(21)02724-0 For more information about DASON, please visit: https://dason.medicine.duke.edu.2022-01-2815 minDASON DigestDASON DigestSimplifying the Management of NeurosyphilisThis episode features Dr. Angelina Davis from DASON. The article reviewed in this episode is available here: https://doi.org/10.1016/s1473-3099(20)30857-4. For more information about DASON, please visit: https://dason.medicine.duke.edu.2022-01-1412 minDASON DigestDASON DigestCOVID Vaccines - Let's Keep Myocarditis in PerspectiveThis episode features Dr. Shaefer Spires from DASON. The article reviewed in this episode is available here: https://doi.org/10.1038/s41591-021-01630-0. For more information about DASON, please visit: https://dason.medicine.duke.edu.2021-12-1713 minDASON DigestDASON DigestMolnupiravir – Finally, an Oral Option for Outpatients with COVID-19This episode features Dr. Travis Jones from DASON. Details regarding the FDA meeting on molnupiravir are available here: https://www.fda.gov/advisory-committees/advisory-committee-calendar/november-30-2021-antimicrobial-drugs-advisory-committee-meeting-announcement-11302021-11302021. For more information about DASON, please visit: https://dason.medicine.duke.edu.2021-12-0916 minDASON DigestDASON DigestThe Status of Antimicrobial Stewardship in the USThis episode features Dr. Melissa Johnson from DASON. The CDC's 2021 report on antibiotic use in the United States is available here: https://www.cdc.gov/antibiotic-use/pdfs/stewardship-report-2021-H.pdf. For more information about DASON, please visit: https://dason.medicine.duke.edu.2021-12-0915 minDASON DigestDASON DigestRace to Start: Beta-lactams or Vancomycin First for Bacteremia?This episode features Dr. Travis Jones from DASON and Dr. Elizabeth Keil, current PGY2 Infectious Diseases Resident at Duke University Hospital. The article reviewed in this episode is available here: https://doi.org/10.1093/cid/ciab865. For more information about DASON, please visit: https://dason.medicine.duke.edu.2021-12-0917 minDASON DigestDASON DigestMSSA Bacteremia: Cefazolin, Final AnswerThis episode features Dr. Travis Jones from DASON. The article reviewed in this episode is available here: https://doi.org/10.1093/ofid/ofab476. For more information about DASON, please visit: https://dason.medicine.duke.edu.2021-12-0912 minDASON DigestDASON DigestJust for Men: An Update on the Management of UTIThis episode features Dr. Angelina Davis from DASON. The article reviewed in this episode is available here: https://doi.org/10.1001/jama.2021.9899. For more information about DASON, please visit: https://dason.medicine.duke.edu.2021-12-0916 minDASON DigestDASON Digest7 Day Treatment Over 14 Days for Enterobacterales Bacteremia, Not Just Non-inferior Anymore!This episode features Dr. Shaefer Spires from DASON. The article reviewed in this episode is available here: https://doi.org/10.1016/j.cmi.2021.09.001. For more information about DASON, please visit: https://dason.medicine.duke.edu.2021-12-0916 minDASON DigestDASON DigestFrom the Front Lines: Impact of Handshake Stewardship in the ICUThis episode features Dr. Elizabeth Dodds Ashley and Dr. Shaefer Spires from DASON, Dr. Jessica Seidleman from Duke Infectious Diseases, and Dr. Christina Sarubbi from UNC Rex Healthcare. The article reviewed in this episode is available here: https://doi.org/10.1093/cid/ciab747. For more information about DASON, please visit: https://dason.medicine.duke.edu.2021-12-0923 minDASON DigestDASON DigestAddition By Subtraction: Optimizing Antibiotic Durations at Hospital DischargeThis episode features Dr. Melissa Johnson from DASON. The articles reviewed in this podcast are available here: https://doi.org/10.1093/ofid/ofab399 https://doi.org/10.1017/ice.2019.118 For more information about DASON, please visit: https://dason.medicine.duke.edu.2021-12-0917 minDASON DigestDASON DigestReal Talk with DASON: COVID-19 VaccinesThis episode features Dr. Travis Jones and Dr. Shaefer Spires from DASON. For more information about DASON, please visit: https://dason.medicine.duke.edu.2021-12-0930 minDASON DigestDASON DigestIdeas for Antimicrobial Stewardship in the EDThis episode features Dr. Angelina Davis from DASON. The articles reviewed in this episode are available using the following links: https://doi.org/10.2146/ajhp090552 https://doi.org/10.1016/j.cmi.2020.10.028 For more information about DASON, please visit: https://dason.medicine.duke.edu.2021-12-0917 minDASON DigestDASON DigestDuration of therapy for Prosthetic Joint Infections, review of a potential game changer study with Dr. Ted HendershotThis episode features Dr. Shaefer Spires from DASON and Dr. Ted Hendershot from the Division of Infectious Diseases at Duke University. The article reviewed in this episode is available here: https://www.nejm.org/doi/full/10.1056/NEJMoa2020198. For more information about DASON, please visit: https://dason.medicine.duke.edu.2021-12-0925 minDASON DigestDASON DigestMetronidazole-associated Neurologic EventsThis episode features Dr. April Dyer from DASON. The article reviewed in this episode is available here: https://doi.org/10.1093/cid/ciaa395. For more information about DASON, please visit: https://dason.medicine.duke.edu.2021-12-0914 minDASON DigestDASON DigestEstimated Clinical and Economic Impact of Reducing Blood Culture ContaminationThis episode features Dr. Travis Jones from DASON and Dr. Kevin Garey from the University of Houston College of Pharmacy. The articles reviewed in this episode are available for download using the following links: https://doi.org/10.1128/CMR.00009-19 https://doi.org/10.1016/j.ajic.2018.12.020 https://doi.org/10.1128/JCM.01015-18 For more information about DASON, please visit: https://dason.medicine.duke.edu.2021-12-0913 minDASON DigestDASON DigestPreoperative Beta-lactam Allergy InterventionThis episode features Dr. Elizabeth Dodds Ashley from DASON and Dr. Shaina Kwiatkowski from Henry Ford Macomb Hospital in Clinton Township, MI. The article by Kwiatkowski and colleagues reviewed in this episode is available here: https://doi.org/10.1093/ajhp/zxab218. For more information about DASON, please visit: https://dason.medicine.duke.edu.2021-12-0922 minDASON DigestDASON DigestStrategies to Optimize Outpatient Antibiotic Prescribing for UTIsThis episode features Dr. Travis Jones from DASON and Dr. Jason Funaro from the Antimicrobial Stewardship Evaluation Team (ASET) at Duke. The article by Dr. Funaro and colleagues reviewed in this episode is available here: https://doi.org/10.1093/ofid/ofab214. For more information about DASON, please visit: https://dason.medicine.duke.edu.2021-12-0919 minDASON DigestDASON DigestDe-Escalation of Broad-Spectrum Antibiotics After Negative Cultures in Patients Admitted with Pneumonia – We Have Work to DoThis episode features Dr. Melissa Johnson from DASON. The article reviewed in this episode is available here: https://doi.org/10.1093/cid/ciaa212. For more information about DASON, please visit: https://dason.medicine.duke.edu.2021-12-0917 minDASON DigestDASON DigestShort-Course Antibiotics: Best Practice Advice from The American College of PhysiciansThis episode features Dr. April Dyer from DASON. The Best Practice Advice from the American College of Physicians is available here: https://doi.org/10.7326/M20-7355. For more information about DASON, please visit: https://dason.medicine.duke.edu.2021-12-0912 minDASON DigestDASON DigestCommunity Acquired Pneumonia: It's All About the NumbersThis episode features Dr. Angelina Davis from DASON. The article reviewed in this episode is available here: https://doi.org/10.1016/S0140-6736(21)00313-5. For more information about DASON, please visit: https://dason.medicine.duke.edu.2021-12-0912 minDASON DigestDASON DigestVancomycin vs Daptomycin – An Old Rival – The Battle ContinuesThis episode features Dr. Shaefer Spires from DASON. The article by Schweizer and colleagues is available here: https://doi.org/10.1093/cid/ciaa1572. The article by Dionne and Lee is available here: https://doi.org/10.1093/cid/ciab247. For more information about DASON, please visit: https://dason.medicine.duke.edu.2021-12-0915 minDASON DigestDASON DigestThe Nose Knows: Using Nasal MRSA PCR to De-Escalate VancomycinThis episode features Dr. Elizabeth Dodds Ashley from DASON. The article reviewed in this episode is available here: https://doi.org/10.1093/ofid/ofab099. For more information about DASON, please visit: https://dason.medicine.duke.edu.2021-12-0913 minDASON DigestDASON DigestDiscussing the DRIP ScoreThis episode features Dr. Cara Nys, a former PGY2 Infectious Diseases Resident at Duke, and Dr. Meredith Oliver, the lead author of the article reviewed in this episode and a Pediatric Infectious Diseases Pharmacist at the University of Minnesota Masonic Children's Hospital. The article reviewed by Meredith Oliver and colleagues is available here: https://doi.org/10.1128/AAC.01482-20. For more information about DASON, please visit: https://dason.medicine.duke.edu.2021-12-0917 minDASON DigestDASON DigestCefiderocol: Seeking Another Option for Serious Gram-Negative InfectionsThis episode features Dr. Angelina Davis from DASON. The CREDIBLE-CR study is available here: https://doi.org/10.1016/S1473-3099(20)30796-9. The APEKS-NP study is available here: https://doi.org/10.1016/S1473-3099(20)30731-3. For more information about DASON, please visit: https://dason.medicine.duke.edu.2021-12-0927 minDASON DigestDASON DigestAntibiotics for Appendicitis: Ready for Prime Time?This episode features Dr. Melissa Johnson from DASON. The CODA Trial reviewed in this podcast is available here: https://www.nejm.org/doi/10.1056/NEJMoa2014320. The APPAC II Trial is available here: https://jamanetwork.com/journals/jama/fullarticle/2775227. For more information about DASON, please visit: https://dason.medicine.duke.edu.2021-12-0914 minDASON DigestDASON DigestAntimicrobial Stewardship Guidance for COVID-19 PatientsThis episode features Dr. April Dyer and Dr. Shaefer Spires from DASON. The article reviewed in this episode is available here: https://doi.org/10.1016/j.cmi.2020.09.041. In addition, the systematic review and meta-analysis of secondary co-infection in patients with COVID-19 is available here: https://www.tarrn.org/covid. For more information about DASON, please visit: https://dason.medicine.duke.edu.2021-12-0914 minDASON DigestDASON DigestCOVID-19 mRNA Vaccine: Myths and Common QuestionsThis episode features Dr. Elizabeth Dodds Ashley and Dr. Shaefer Spires from DASON. The DASON newsletter on the topic of COVID-19 Vaccine Q&As referenced in this episode is available for download here: https://dason.medicine.duke.edu/newsletters. For more information about DASON, please visit: https://dason.medicine.duke.edu.2021-12-0919 minDASON DigestDASON DigestA Preview of the Upcoming Changes to the IDSA C. difficile Treatment GuidelinesThis episode features Drs. Elizabeth Dodds Ashley and Travis Jones from DASON and Dr. Kevin Garey from the University of Houston College of Pharmacy in Houston, Texas. The latest IDSA/SHEA C. difficile guidelines are available here: https://doi.org/10.1093/cid/ciab549. For more information about the Duke Antimicrobial Stewardship Outreach Network (DASON), please visit: https://dason.medicine.duke.edu.2021-12-0925 minDASON DigestDASON DigestOptimizing Treatment for ESBL-Producing PathogensEpisode Notes This episode features Dr. Elizabeth Dodds Ashley and Dr. Shaefer Spires. The article discussed in this podcast is available here: https://doi.org/10.1093/cid/ciaa1479. For more information about the Duke Antimicrobial Stewardship Outreach Network (DASON), please visit: https://dason.medicine.duke.edu.2021-12-0917 min