Shows
The Flux by EpistemixStrategic Innovation in Public Health with Les CraigLes Craig joins us to discuss how simulation and synthetic data are changing the way organizations prepare for infectious disease outbreaks. From helping public health leaders visualize complex scenarios to enabling pharmaceutical companies to explore new R&D pathways, Les explains how advanced modeling technology empowers faster, smarter decisions. This episode unpacks how simulation can move ideas from theory to action and why creating low-risk environments for experimentation is key to building long-term trust and value in emerging tech.2025-07-0827 minThe Flux by EpistemixDesigning for Uncertainty with Mickey McManusIn this episode of The Flux, host John Cordier sits down with innovation pioneer Mickey McManus to explore what it means to design for uncertainty in a world where complexity is the norm. Mickey draws on decades of experience from leading Maya Design and shaping decision-support tools for DARPA, to helping build the Future of Learning team at Autodesk to share insights on how human-centered design, systems thinking, and simulation can empower better decisions when the stakes are high and clarity is scarce.Together, John and Mickey unpack stories ranging from battlefield strategies in Iraq to fifth-grade...2025-06-2351 minThe Flux by EpistemixThe Role of Sentiment and Social Dynamics in Public Health Models with Philippe GiabbanelliIn this episode of The Flux, we explore how modeling trust, belief, and social sentiment can unlock deeper insights in public health. Our guest, Philippe Giabbanelli, shares how agent-based models are evolving to capture not just behaviors, but the opinions and social dynamics that drive them like vaccine hesitancy or trust in institutions. We discuss the challenges of representing complex human psychology in simulations, the importance of sentiment in shaping real-world outcomes, and how these models are being used to support decision-making in uncertain, high-stakes environments. If you’ve ever wondered how data can reflect what people think, not ju...2025-06-0942 minThe Flux by EpistemixGlory Days of Modeling: Dan Eichelsdoerfer on Building MacrocosmIn a world full of linear thinking, Dan Eichelsdoerfer is building a company grounded in complexity. In this episode, Dan joins The Flux to discuss why agent-based models are finally ready for prime time and how Macrocosm is creating tools to simulate economic and energy systems with more nuance, flexibility, and realism than ever before.Dan talks about the interdisciplinary “glory days” of modeling inside Macrocosm, where economists, physicists, and data scientists come together to break old paradigms and challenge assumptions. From applying agent-based models to simulate energy markets to envisioning what sustainable economics might actually look like...2025-05-1941 minThe Flux by EpistemixFrom Chaos to Clarity with Doyne Farmer: Why Agent-Based Models Matter NowOn this episode of The Flux, agent-based models (ABMs) have long lived on the fringes of mainstream economics but that’s changing. Doyne Farmer breaks down how advances in computing and data are fueling a new era of bottom-up modeling. He explains where ABMs outperform traditional models, why certain fields (like epidemiology and traffic systems) adopted them earlier, and how economics is finally catching up. We explore the structural and behavioral complexity that ABMs are uniquely suited to handle and what it will take to shift institutional thinking in policy and business.2025-05-0547 minThe Flux by EpistemixMining Meaning: Laura Sheppard on Gender, Academia, and the Power of Public DataIn this episode of The Flux, we talk with Laura Sheppard, a research fellow at University College London’s Centre for Longitudinal Studies, about how data mining can uncover powerful insights from unexpected sources. Laura shares her work using the British Library’s Ethos dataset, a comprehensive record of UK doctoral theses - to explore gender inequality in higher education. We discuss the process of inferring gender from names, the challenges of working with messy or incomplete data, and how publicly available datasets can be creatively repurposed to answer socially important questions. Laura also touches on her work with The...2025-04-2239 minThe Flux by EpistemixFrom Micro-Behaviors to Macro-Patterns: Exploring Agent-Based Models with Andrew CrooksIn this episode of The Flux, host John Cordier sits down with Andrew Crooks at the Complex Social Systems Society Conference in Santa Fe. They dive into the world of agent-based modeling (ABM) - what it is, why it matters, and how it helps us simulate and better understand human behavior in complex systems. From simulating traffic jams to modeling social influence on vaccine uptake, Andrew shares how data, geography, and synthetic populations are revolutionizing our ability to forecast and inform decisions. They also explore the growing role of AI tools in democratizing modeling, the evolution of computational capabilities...2025-04-0930 minThe Flux by EpistemixFrom Neural Networks to Synthetic Populations: Hamdi Kavak’s JourneyWhat if we could predict the impact of a pandemic, a policy change, or even a war before it happens? Hamdi Kavak joins The Flux to discuss how agent-based modeling enables researchers to explore "what if" scenarios and simulate real-world behaviors at both small and massive scales. We dive into the applications of ABM in government-funded projects, the difficulties of modeling millions of agents, and how better communication of simulation insights could improve public trust in data-driven decision-making. If you're curious about the future of modeling and simulation, you won’t want to miss this conversation.2025-03-1725 minThe Flux by EpistemixFrom Curiosity to Complexity: Paul Amoruso’s Journey into Agent-Based ModelingIn this episode of The Flux, host John Cordier, CEO of Epistemix, sits down with Paul Amoruso to explore his unexpected journey into the world of agent-based modeling (ABM). What started as a course recommendation turned into a passion for understanding complex systems and using data to drive better decisions.Paul shares insights from his academic path, the value of interdisciplinary collaboration, and why ABMs foster explainability in research. He also discusses how modeling could reshape fields like education and improve knowledge diffusion. Plus, in our What the Flux moment, Paul reflects on how we might have...2025-03-0418 minThe Flux by EpistemixFrom Curiosity to Complexity: Paul Amoruso’s Journey into Agent-Based ModelingIn this episode of The Flux, host John Cordier, CEO of Epistemix, sits down with Paul Amoruso to explore his unexpected journey into the world of agent-based modeling. What started as a course recommendation turned into a passion for understanding complex systems and using data to drive better decisions.Paul shares insights from his academic path, the value of interdisciplinary collaboration, and why ABMs foster explainability in research. He also discusses how modeling could reshape fields like education and improve knowledge diffusion. Plus, in our What the Flux moment, Paul reflects on how we might have transformed...2025-03-0417 minThe Flux by EpistemixComplexity in Government Contracting: Jim Malone's Journey into Computational Social ScienceIn this episode of The Flux, host John Cordier interviews Jim Malone at the Complex Social Systems Conference in Santa Fe. Jim, an experienced government acquisition professional, shares his fascinating journey from contracting to pursuing a PhD in Computational Social Science. He discusses the importance of understanding complexity in systems, particularly in government contracting and policy-making. Jim explores how modeling and data analysis can revolutionize our approach to measuring value in federal spending and its impact on various sectors. This thought-provoking conversation delves into the intersection of complexity science, policy, and the potential for creating more effective and value-driven...2025-02-1918 minThe Flux by EpistemixDecision-Making in Complex Systems: Insights from Agent-Based Modeling with Aaron FrankWelcome to The Flux! In this episode, host John Cordier, CEO at Epistemix, explores the intricacies of agent-based modeling and its impact on decision-making with Aaron Frank. Recorded live at the Complex Social System Society of America's conference in Santa Fe, New Mexico, Aaron shares his journey from traditional national security research to computational models and agent-based simulations. The discussion covers the evolution and application of agent-based modeling in national security, urban planning, public health, and beyond. Dive deep into how these models can create more informed decisions amidst uncertainty and their potential to transform various sectors. Join us...2025-01-2838 minThe Flux by EpistemixDemocracy 3.0: Bridging Policy and Technology with Tom PikeIn this episode of The Flux, hosted by John Cordier, CEO at Epistemix, we delve into the fascinating world of agent-based modeling (ABM) with Tom Pike, co-lead for MESA. Recorded live at the Complex Systems Society conference in Santa Fe, New Mexico, Tom shares insights on democratizing ABM through Python, its significance in decision-making, and innovative applications such as COVID-19 policy modeling in Costa Rica. The discussion explores the accessibility challenges of ABM, the potential of large language models, and the transformative vision of 'Democracy 3.0.' Tune in to learn about the impact of ABM in fields ranging from...2025-01-1424 minThe Flux by EpistemixRandy Burgh: Insights from Economic Development and Complexity EconomicsThis episode explores the economic development potential of technology developed in New Mexico, focusing on industry-based research and the collaboration between companies, universities, and government labs. It delves into the evolution of technology, highlighting key insights from Dr. Brown of the Santa Fe Institute, whose work integrates the concepts of evolutionary technology and complexity economics, particularly through agent-based modeling and combinatorial science.00:00 Introduction to Economic Development in New Mexico00:09 The Triple Helix Model: Industry, Universities, and Government00:40 Shout Out to Dr. Brown and His Contributions00:54 Complexity Economics and Technology Evolution01:12 Understanding Combinatorial Science2025-01-1337 minThe Flux by EpistemixNavigating Complexity: Timothy Clancy on Modeling and Policy-MakingIn this episode of The Flux, hosted by John Cordier, CEO of Epistemix, we hear from Timothy Clancy, a researcher from the University of Maryland's START program. Recorded at the Complex Social Systems Society of the Americas Conference in Santa Fe, New Mexico, Clancy shares insights from his career, which spans government work and applied studies on national security. They discuss the evolution of modeling in policy-making, the challenges of visualizing complex data, and the importance of building trust with policy-makers. Clancy emphasizes the need for simplicity in communication, the enduring nature of integrating soft skills with technical models...2024-12-1632 minThe Flux by EpistemixExploring Agent-Based Modeling for Complex Policy Challenges with Sherwin BrownIn this episode of The Flux, host John Cordier, CEO at Epistemix, interviews Sherwin Brown from MITRE. Sherwin shares his journey into agent-based modeling, starting from his background in health management and policy. He discusses the role of data science and analytics in solving complex problems, such as monitoring the impact of the Affordable Care Act and tackling issues like homelessness and opioid overdoses. Sherwin emphasizes the importance of visual storytelling in agent-based modeling and its potential to support decision-making in policy contexts. The episode also highlights the importance of community and curiosity in the field of agent-based modeling.2024-12-0210 minThe Flux by EpistemixExploring Data-Driven Decision Making with Bill RandIn this episode of 'The Flux,' we dive deep into data-driven decision making with Bill Rand from NC State University. Join us as Bill discusses his work in agent-based modeling, social media misinformation, and various innovative projects. Discover how agent-based modeling can provide insights into human behavior, business analytics, and even intergenerational trauma. Learn how different modeling approaches can help forecast outcomes, refine decision-making processes, and provide better policy and business strategies. Perfect for anyone interested in AI, data science, and the social sciences.00:00 Introduction to the Flux Podcast00:20 Meet Bill Rand...2024-11-1840 minThe Flux by EpistemixRevolutionizing Engineering: The Power of AI and Simulation with Dave FreedIn this episode of The Flux, join Dave Freed, Senior Director at Ansys, as he delves into the transformative world of computer simulations. With a rich history from Exa Corporation to OnScale and Ansys, Dave explores the evolution and future of simulations, highlighting their pivotal role in automotive, aerospace, and nuclear engineering. Discover how simulations have advanced to replace costly physical testing, improve accuracy, and prevent errors. Learn about intriguing real-world applications, the integration of AI in automating complex tasks, and the surge of simulation in life sciences. Dave also shares personal experiences and acknowledges mentors who've shaped his...2024-11-0439 minThe Flux by EpistemixTransforming Data into Decisions: Insights from Matt Madden at BYUIn this episode of The Flux, host John Cordier interviews Matt Madden, Director of the BYU Marketing Lab, about his work in making complex statistics and marketing analytics accessible. Madden discusses the lab's unique approach, which allows students to apply their skills in real-world consulting projects. They delve into key topics like market research techniques such as conjoint analysis, which helps students and clients understand consumer behavior more accurately than traditional surveys.Madden shares his journey from math education to statistics and ultimately to marketing, providing insights into how data can guide consumer insights while acknowledging its...2024-10-2144 minThe Flux by EpistemixNavigating Complex Systems with Don Burke: Epidemiology, AI, and ModelingIn this episode of The Flux, host John Cordier sits down with Don Burke, co-founder of Epistemix and a trailblazing epidemiologist, to explore the fascinating intersection of infectious disease research, artificial intelligence, and agent-based modeling (ABM). Burke shares his journey from a traditional career in infectious disease research to becoming a passionate advocate for modeling and simulation, offering a behind-the-scenes look at his groundbreaking work with HIV, vaccines, and global disease prevention.Burke recounts his early days in the military, developing vaccines for tropical diseases and his epiphany when he first encountered genetic algorithms and artificial intelligence...2024-10-0744 minThe Flux by EpistemixThe Tipping Point for Agent-Based Modeling with Rob AxtellIn this episode of The Flux, John Cordier interviews Rob Axtell fromGeorge Mason University, where he leads the largest graduate programin agent-based modeling (ABM) globally. Axtell shares his journey intocomplex systems modeling and how the field has evolved since the1990s. He explains how George Mason’s Ph.D. program inComputational Social Science is shaping the next generation of expertswho go on to roles in government, research, and the private sector.They discuss the power of agent-based models to simulate real-worlddynamics, from consumer behavior to...2024-09-3040 minThe Flux by EpistemixThe Intersection of Science Fiction and Reality: A Conversation with Sam ArbesmanIn The Intersection of Science Fiction and Reality episode of The Flux podcast, host John Cordier engages in a conversation with Sam Arbesman, Scientist-in-Residence at Lux Capital and Research Fellow at the Long Now Foundation. They explore how science fiction, video games, and computational social science intersect to influence real-world innovations.Harbisman shares how early experiences like playing SimCity and reading Isaac Asimov's Foundation Trilogy sparked his interest in complexity science and computational modeling. They discuss the concept of psychohistory from Foundation, and how it inspired modern computational social science to analyze societal behaviors on a large...2024-09-1737 min
Meat & Potatoes PodcastM&P Ep. 253 John Cordier, EpistemixWelcome to another exciting episode of the Meat and Potatoes podcast! In this episode, we sit down with John Cordier, co-founder and CEO of Epistemix, a groundbreaking company that spun out of the University of Pittsburgh and Carnegie Mellon. Epistemix is revolutionizing the way we forecast the spread of diseases, human behavior, and even economic trends using agent-based simulation models. 00:03 - Introduction and Guest Welcome 00:40 - Founding Story of Epistemix 02:04 - Early Applications and Public Health Goals 02:50 - Emergent Infectious Diseases and Biodefense 04:49 - Epidemic X and Human Behavior 06:05 - Behavioral Differences and Forecasting 08:08 - Economic Forecasting and Agent-Based Simulation 10:03...2024-09-0528 minThe Flux by EpistemixThe Growing Impact of Agent-Based Modeling with Matt KohlerIn this episode of The Flux, John Cordier interviews Matt Kohler, Applied Complexity Scientist at MITRE and President of the Computational Social Science Society of the Americas, about the transformative power of agent-based modeling (ABM). Kohler explains how ABM simulates complex human systems and helps decision-makers understand the ripple effects of their choices. From anthropology to economics, Kohler shares examples of how ABM is helping scientists and leaders explore new insights.As technological advancements in data, hardware, and software drive ABM to new heights, Kohler discusses its expanding role in solving real-world challenges, from traffic modeling to...2024-09-0332 minThe Flux by EpistemixThe Future of Agent-Based Modeling: Insights from Josh EpsteinIn the inaugural episode of The Flux, John Cordier, CEO of Epistemix, interviews Josh Epstein, Director of the Agent-Based Modeling Lab at NYU and a prominent figure at the Santa Fe Institute. The discussion revolves around the potential and progress of agent-based modeling (ABM), particularly in public health, economics, and beyond.Epstein shares insights into how ABM creates simulations of artificial societies to generate real-world patterns like epidemics or wealth distributions. He highlights the generative explanatory standard, which uses individual agent behaviors to explain macroscopic phenomena, contrasting it with traditional models that assume rational actors. Epstein introduces...2024-08-1439 min
AWS Health Innovation Podcast#93, Harnessing Data to Scale Innovations, Part Five of the Health Innovation Compilation SeriesTo scale health innovation, we need to take a broad view and redefine the art of the possible in Real-World Evidence, Data & Population Health. In the fifth and final episode of our Health Innovation Compilation Series, we hear from Mendel, Akrivia Health, Epistemix, Ovation, and Evidation Health, innovative companies that are transforming how we leverage data to drive better health outcomes.
1. How does Mendel reconcile conflicting medical data?
Mendel's AI structures unstructured patient data into coherent journeys, reconciling conflicting information from sources like pathology reports and genomics.
It enables querying consolidated data through intuitive interfaces, providing faster...2024-07-0959 min
Trade Show Talk PodcastEp. 56 - Transforming Live Events: Freeman CEO Bob Priest-Heck Reflects on Innovation, Leadership & the Future of the Events IndustryBob Priest-Heck joined Trade Show Talk to share his experience as CEO of Freeman, a privately owned global events company that employs more than 4,500. As he prepares to step down from his role on June 28 after 15 years at Freeman and six years at the helm, Priest-Heck reflected on the risks and rewards of his career that spans more than 35 years in the events industry. We talked about the early days when he was on the show management side and had a front-row seat to launching and producing massive tech events during the Internet boom. Under his leadership at Freeman...2024-06-2150 minAWS Health Innovation Podcast#71, Simulating the Future of Public Health, with John Cordier of EpistemixAs we try to keep up with a world being transformed by data driven decision making, the potential value of a tool that simulates the future of public health is profound. On this episode of the AWS Health Innovation Podcast, Yin He from AWS Startups speaks with John Cordier, the CEO & Co-Founder of Epistemix, who built a platform for running realistic simulations of human populations, simulations that reveal crucial points of leverage where a single decision can have extraordinary impact, providing game-changing capabilities to health plans and systems.
Population Health Simulation [02:05]: Discover Epistemix's synthetic population health engine and...2023-11-2132 min
Entrepreneur RxRX59: Entrepreneur Rx Interview with John Cordier, MBA, MHA, CEO and Founder of EpistemixWelcome back to Entrepreneur Rx!
This week on the podcast, John interviews John Cordier, founder and CEO at Epistemix. Epistemix is a company that uses computational modeling and mathematics for decision support in public health through synthetic population data, testing interventions to improve outcomes with infectious diseases.
Epistemix understands that even a small behavior change can affect the greater outcome. So, they have built a platform where researchers can test out different interventions and policies and simulate outcomes to inform decision and policymakers about the potential results. John also shares insights on the journey Epistemix...2022-12-1440 min
IBF On DemandSimulating Consumer Behaviour For Demand Forecasting01:43 Appling COVID forecasting models for business problems03:23 We're not forecasting numbers but how consumers react to different stimuli05:21 John Cordier, CEO of Epistemix, pushing the boundaries of predictive analytics08:10 Modelling variables like behavior and policy that spread diseases12:20 Most companies use only internal data which stops us from spotting changes14:06 Testing assumptions to identify the tipping point of behavioral change before they happen14:15 Understanding the 'why' of behavioral change16:30 What synthetic data is 18:23 Modelling adoptions curves for diseases and consumer products is the same19:24 Simulating the interactions between people, things a...2022-11-2130 min
Straight Talk – an ISSA PodcastCases Rapidly Rising as the 'Stealth' Variant Creates Global ConcernA new version of the omicron variant is starting to get the attention of scientists, health professionals, and the cleaning industry. Known as "BA.2" or the "stealth" strain, there are concerns about this genetic mutation and how it may become a health issue especially with certain demographics.In this episode of GBACtv's BioTalk, hear from Patty Olinger, GBAC executive director, and John Cordier, CEO and co-founder of Epistemix, on what you need to know right now as information emerges on this variant.2022-03-2118 minStraight Talk – an ISSA PodcastAs Masks Come Off, Cleaning and Building Sciences Take Over in the Fight to Improve IAQIn this episode of BioTalk, a GBACtv production, learn how the cleaning industry can respond to an increased risk of indoor air contamination and how building sciences is identifying critical issues and addressing them. John Cordier, Epistemix CEO, and University of Colorado's College of Engineering’s Mark Hernandez share thought-provoking solutions for improving indoor air quality while addressing cleaning and contamination issues.2022-03-0428 min
Back @ IT ShowBack @ IT: How Epidemics Impact Ideas and Behaviors with John CordierEpidemic. We hear that word and immediately conjure bad images in our heads. Rightly so, as much of this can be attributed to false ideas and behaviors.But, what if epidemics could be seen in a positive way?For context, Merriam-Webster defines the word epidemic as this: “affecting or tending to affect a disproportionately large number of individuals within a population, community, or region at the same time“.Based on this definition, we should be striving to affect the world around us by spreading more than just disease, but compassion, creativity, positivity, and awar...2021-09-2736 min
The3MuslimsE72 | Imran Hussein Epistemix Talks Objective Morality, Feminism, Egocentrism and Marriage | T3MYoutube/Patreon: The3Muslims
Instagram: @the3muslims2021-08-061h 09
Blood BrothersSubboor Ahmad & Imran Hussein | Dawah dramas | BB #40In this special episode of the Blood Brothers Podcast, Dilly Hussain speaks with prominent Muslim apologists and debaters, Subboor Ahmad and Imran Hussain from IERA. #BloodBrothersPodcast #Dawah #Atheism
In this in-depth conversation, Dilly questions Subboor and Imran about the clashes of personalities and ideas within dawah organisations and how to overcome disagreements.
Imran who is the founder of the Epistemix YouTube channel explains how the rise of atheism didn't occur in a vacuum and was intrinsically linked to the industrial revolution and European colonialism, while Subboor (Darwinian Delusions YouTube channel) argues that geopolitical and material intere...2021-04-031h 27
Young SmirksEP52 - Imran HusseinJohn Fontain meets Imran Hussein and talks about the London Dawah movement and Epistemix.
Be sure to follow us on Instagram, YouTube and all the other outlets. Like, subscribe and leave a comment and also, please support us on the donation linkso we can continue to give you quality podcasts.2020-09-0526 min
TechdirtModeling The PandemicAs the coronavirus pandemic continues, nobody really knows what's going to happen — especially if kids start going back to school. Statistical models of the possibilities abound, but this week we're joined by some people who are taking a different approach: John Cordier and Don Burke are the founders of Epistemix, which is using a new agent-based modeling approach to figure out what the future of the pandemic might look like.2020-08-0545 min