Shows
This Is Why with Dr. BustiHeart Borders & Chambers on a Chest X-Ray - Made EasyIn this lecture from This is Why, Dr. Busti will make the identification of the heart borders and heart chambers on a chest x-ray easy. Dr. Busti will walk step-by-step through how to identify the cardiac silhouette, locate the heart borders, and understand where the right atrium, left atrium, right ventricle, left ventricle, left atrial appendage, and apex of the heart sit on a standard PA chest x-ray (CXR).You’ll see how to connect real heart xray images with the underlying heart anatomy.You’ll learn how to:- Identify normal heart borders on a...
2025-12-2316 minThis Is Why with Dr. BustiWhat is Dysphagia? Definition, Causes, & PitfallsIn this lecture from This is Why, Dr. Busti will break down dysphagia—the medical term for difficulty swallowing—in a clear, clinically relevant way. You’ll learn what dysphagia means, how clinicians use the term, and how to quickly recognize the difference between oropharyngeal dysphagia vs esophageal dysphagia. We’ll also cover high-yield dysphagia causes, red flags, and common pitfalls that lead to missed diagnoses—especially when aspiration risk is overlooked.What you’ll learn (quick + practical):- Dysphagia definition and how it shows up in real patients (“trouble swallowing)- Oropharyng...
2025-12-2312 minThis Is Why with Dr. BustiChest X-Ray Exposure: How to Tell If Your CXR Is AdequateAre you looking at a portable chest x-ray and wondering, “Is this exposure good enough to trust?” In this video, we walk through how to check chest x-ray exposure step-by-step so you can quickly decide if a CXR is adequately penetrated and ready for interpretation. In this lecture from This is Why, Dr. Busti will provide you with a practical approach to how to read chest x-rays and judge image quality before making clinical decisions.You’ll learn how to:Recognize adequate CXR penetration using the “spine through the heart” ruleApply a simple chest x-ray qual...
2025-12-2212 minThis Is Why with Dr. BustiHow to Easily Identify & Count Ribs on a Chest X-RayIn this lecture from This is Why, Dr. Busti will walk step-by-step through rib anatomy on a portable AP chest x ray, so you can quickly recognize posterior vs anterior ribs, assess inspiratory effort, and improve your overall chest x ray interpretation skills.You’ll learn how to:Spot posterior ribs and anterior ribs on a standard AP chest x rayUse rib counting to judge film quality and inspirationApply rib levels as landmarks when describing lung findingsAvoid common mistakes when reading portable chest x rays in the ER, ICU, and in...
2025-12-1913 minThis Is Why with Dr. BustiPenicillin Allergy & Cephalosporin Cross-ReactivityIn this lecture from This is Why, Dr. Busti will answer the question, "Are patients with a penicillin allergy really at high risk when we use cephalosporins?" Dr. Busti will also discuss some of the evidence on penicillin allergy & cephalosporin cross-reactivity and shows you how to safely use β-lactam antibiotics in clinical practice.In this episode, we’ll cover:- Why most penicillin allergy labels are incorrect- The true risk of cephalosporin cross-reactivity (and why it’s not what you think)- How R1 side chains drive cross-reactivity between β-lactam antibiotics- Practi...
2025-12-1913 minThis Is Why with Dr. BustiWhat Does Micturate Mean? Medical Terms Made Easy & RelevantWhat does “micturate” actually mean, and why do textbooks, exam questions, and older charts still use it instead of just saying “urinate”? In this lecture on Medical Terminology from This is Why, Dr. Busti breaks down the meaning and definition of micturate, how it relates to micturition and urination, and shows you exactly how this term is used in real clinical practice so it finally sticks.In this video, you’ll learn: what micturate and micturition mean in plain language, how to connect “micturate = urinate” so you never freeze on an exam, how the term shows up in phrases lik...
2025-12-1904 minThis Is Why with Dr. BustiPractice Question: Penicillin Allergy - Avoiding Cross-ReactivityMaster penicillin allergy questions exactly the way they show up on your exams and in clinical practice. In this episode of This is Why, Dr. Busti will walk through a high-yield practice question on penicillin allergy and beta-lactam cross-reactivity, so you know which antibiotics are safe, which to avoid, and how to reason through the stem under exam pressure.You’ll learn how to:- Analyze a penicillin allergy history in an exam-style MCQ- Understand penicillin–cephalosporin cross-reactivity and when it actually matters- Apply beta-lactam cross-reactivity concepts (penicillins vs. cephalosporins) to patient care...
2025-12-1807 minThis Is Why with Dr. BustiHow to Check Patient Positioning on a Chest X-RayMastering chest X-ray positioning is the first step to safe and accurate chest X-ray interpretation. In this video, “How to Check Patient Positioning on a Chest X-Ray,” Dr. Busti walk through a simple, practical checklist so you can quickly decide if a CXR is good enough to interpret—or if positioning errors (rotation, poor inspiration, clipping) are misleading you.You’ll learn how to:Tell PA vs AP views and why it matters for heart size and mediastinumSpot patient rotation using the clavicles and spinous processesAssess inspiration on a chest X-ray (how many rib...
2025-12-1616 minThis Is Why with Dr. BustiAP vs PA Chest X-Ray: How to Tell the DifferenceIn this lecture from This is Why, Dr. Busti will teach you how to quickly and confidently tell AP vs PA chest X-ray (CXR) views apart so you don’t get misled by magnified hearts or a widened mediastinum. In this video, we break down chest X-ray projection step by step and show you how to spot whether a film is AP or PA view just by looking at the image itself—skills you can use on your next shift or exam.This teaching video is designed to help clinicians who want practical, bedside chest X-ray interpretation skil...
2025-12-0513 minThis Is Why with Dr. BustiHow to Tell If Chest X-Ray Inspiration Is Adequate (Portable CXR Tips)In this lecture from This is Why, Dr. Busti will walk step-by-step through the proper steps to determine if the inspiration is good enough to allow the chest x-ray (CXR) to be appropriate to interpret and avoid missing an abnormality. This lecture will improve your overall chest x-ray interpretation skills.You’ll learn how to:Identify the posterior ribs and anterior ribs on a standard AP chest x rayUse rib counting to judge film quality and inspirationIf you’re looking for a clear, visual guide to how to read a chest x ray...
2025-12-0410 minThis Is Why with Dr. BustiSSRI Antidepressants: Pharmacology Made Easy & Clinically RelevantIn this This Is Why pharmacology review, Dr. Busti walks through the Selective Serotonin Reuptake Inhibitors (SSRIs)—how they became first-line for major depressive disorder and a wide range of anxiety-related disorders, and where their real-world pitfalls live.We compare the core agents—citalopram, escitalopram, fluoxetine, fluvoxamine, paroxetine, and sertraline—covering indications, mechanism, and clinical nuances that matter at the bedside. You’ll learn how dose, half-life, metabolism, and side-effect patterns influence patient-specific choices, and what to monitor for safety and success.This episode includes practical guidance on:Managing sexual dysfunction, QT risk, and SIADHRec...
2025-11-2034 minThis Is Why with Dr. BustiChest X-Rays: How to Read Like a Pro - A Step-by-Step GuideThis session teaches a reproducible, step-by-step approach to chest X-ray (CXR) interpretation using two complementary mnemonics: RIPE (Rotation, Inspiration, Penetration/Projection, Exposure/Artifacts) to verify image quality, and A-B-C-D-E-F-G-H-I to read findings in a consistent order. Viewers learn to spot essential landmarks (trachea, aortic knob, hila, lobes/fissures, diaphragms, costophrenic angles), recognize when AP vs PA matters (e.g., cardiothoracic ratio), and avoid common pitfalls that lead to misses. A live, real-time read ties the method together so the approach can be used on rounds, in clinic, or at the bedside.What...
2025-11-1139 minThis Is Why with Dr. BustiChest X-Rays: How to Read Like a Pro - A Step-by-Step GuideThis session teaches a reproducible, step-by-step approach to chest X-ray (CXR) interpretation using two complementary mnemonics: RIPE (Rotation, Inspiration, Penetration/Projection, Exposure/Artifacts) to verify image quality, and A-B-C-D-E-F-G-H-I to read findings in a consistent order. Viewers learn to spot essential landmarks (trachea, aortic knob, hila, lobes/fissures, diaphragms, costophrenic angles), recognize when AP vs PA matters (e.g., cardiothoracic ratio), and avoid common pitfalls that lead to misses. A live, real-time read ties the method together so the approach can be used on rounds, in clinic, or at the bedside.What...
2025-11-1141 minThis Is Why with Dr. BustiPredicting Your NCLEX-RN Success: Why Some Pass & Some Don'tIn this episode of This Is Why, Dr. Busti breaks down the evidence-based predictors of NCLEX-RN success for first-time test takers. See what the 10-year pass-rate trend really shows, which factors (GPA, standardized exit exams, program environment, life experience) matter most, and—most importantly—what you can do now to raise your odds on test day.Build confidence in your exam readiness and clinical mastery with free resources at https://thisiswhy.healthDisclaimer: This content is for educational purposes only and is not intended to p...
2025-11-1108 minThis Is Why with Dr. BustiBPS Exam Pass Rates & Predictors of Success: How to Improve Your OddsBPS specialty board exams are challenging — and the data proves it. But knowing what drives success can make all the difference.In this episode of This Is Why, Dr. Busti reviews national BPS pass rate trends and explores what separates first-time test takers who succeed from those who don’t. Using data from multiple specialties, he highlights how residency training, study strategy, and preparation methods predict success — and why relying solely on memorization or guesswork fails so many candidates.You’ll learn how to interpret your own readiness, avoid common traps like overemphasizing blueprints or anecdota...
2025-10-2714 minThis Is Why with Dr. BustiBPS Exams: Study What is Testable to Maximize SuccessPassing a BPS specialty exam takes more than hard work — it takes strategy and understanding.In this episode of This Is Why, Dr. Busti breaks down how BPS exams are built, what “testable” really means, and why focusing on validated, evidence-based concepts gives you a major advantage. Drawing on decades of experience as a pharmacist, educator, and exam review developer, he explains the multi-step process used to create fair, reliable, and job-related BPS exams.Listeners will learn why not all new or clinically relevant content appears on the test, how to interpret the exam blueprint effect...
2025-10-2714 minThis Is Why with Dr. BustiPredicting Your NAPLEX Success: How to Boost Your First-Time Pass RateWhat predicts success on the NAPLEX? It’s not chance — it’s about understanding the factors that matter most.In this episode of This Is Why, Dr. Busti unpacks the key predictors of NAPLEX performance based on data and published literature. You’ll learn how GPA, pre-admission metrics, clinical performance, study effort, and test timing correlate with first-time pass rates — and how to interpret these factors to improve your own odds.Drawing from decades of experience teaching pharmacy and preparing students for licensing exams, Dr. Busti helps listeners identify what’s within their control and how to act o...
2025-10-2709 minThis Is Why with Dr. BustiStudy Smarter for the NAPLEX: What’s Really Testable?The NAPLEX isn’t testing everything you’ve ever learned — it’s measuring what matters most for entry-level pharmacist competence.In this episode of This Is Why, Dr. Busti explains how the NAPLEX is built by the NABP, why understanding its blueprint helps you focus your studying, and how to avoid wasting time on untested or emerging content. Drawing on his own experience as a pharmacist, physician, and nurse — and decades teaching pharmacy students — he reveals the process behind question validation, exam updates, and psychometric testing.Listeners will learn how to identify high-yield, testable concepts that align w...
2025-10-2712 minThis Is Why with Dr. BustiWhy NAPLEX Scores are Low & How to Reverse the TrendOver the past decade, NAPLEX pass rates have dropped — sparking concern across pharmacy education. But what’s really driving this decline?In this episode of This Is Why, Dr. Busti breaks down the data behind NAPLEX performance trends, exploring factors such as the rapid growth of pharmacy schools, shifts in applicant pools, and the impact of the COVID-19 pandemic on learning and assessment.Drawing from decades of experience as a pharmacist, physician, and nurse, Dr. Busti helps listeners understand how these changes have shaped the profession — and what students can do to overcome them. You’ll learn...
2025-10-2713 minThis Is Why with Dr. BustiNCLEX-RN: Study Smarter, Pass Faster: : Focus on What MattersPassing the NCLEX-RN isn’t about memorizing more — it’s about understanding what truly matters and how the exam is built to measure it. In this episode of This Is Why, Dr. Busti, a physician and pharmacist who began his healthcare career as a registered nurse, breaks down how the NCLEX-RN is developed by the National Council of State Boards of Nursing (NCSBN) — and what that means for your study plan.You’ll learn how to recognize high-yield, testable concepts, why some new content won’t appear on the exam, and how to focus your preparation on what can act...
2025-10-2708 minThis Is Why with Dr. BustiPractice Question: Pneumonia Treatment - As Seen on Your ExamsIn this episode of This Is Why, Dr. Busti walks through a real-world board-style question on community-acquired pneumonia — connecting core pathophysiology to exam reasoning and clinical judgment. Using a 54-year-old patient case, you’ll learn how to differentiate inpatient versus outpatient management, apply CURB-65 and PSI scoring tools, and identify sepsis criteria that drive treatment decisions.Dr. Busti also unpacks the rationale behind antibiotic selection, comparing macrolide monotherapy, beta-lactam combinations, and fluoroquinolone alternatives — all while reinforcing how understanding why each answer choice is correct or incorrect leads to long-term mastery.If you’re preparing for your boa...
2025-10-0721 minThis Is Why with Dr. BustiSmoking Cessation Agents: Pharmacology Made Easy & Clinically RelevantDr. Busti reviews pharmacologic options for smoking cessation—bupropion, nicotine replacement therapy, and varenicline—highlighting mechanisms, dosing strategies, and safety considerations. Learn how to integrate these therapies with behavioral approaches, tailor choices to patient comorbidities, and monitor for clinically relevant risks.Access bonus materials and downloads at https://thisiswhy.healthDisclaimer: This content is for educational purposes only and is not intended to provide medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advi...
2025-10-0735 minThis Is Why with Dr. BustiTCAs (Tricyclic Antidepressants): Uses, Risks & Practical MonitoringDr. Busti reviews tricyclic antidepressants (TCAs)—their history, evolving role, and why they remain relevant today. Learn how tertiary vs. secondary amines differ, why lower doses are effective for pain and insomnia, and how overdose risks tie back to sodium channel blockade. Practical monitoring, counseling tips, and clinical pearls are highlighted to help you apply TCAs safely and effectively.Access bonus materials and downloads at https://thisiswhy.healthDisclaimer: This content is for educational purposes only and is not intended to provide medical advice, diagnosis, or treatment. Always seek the advice of your physician or ot...
2025-10-0739 minThis Is Why with Dr. BustiTCA Antidepressants: Pharmacology Made Easy & Clinically RelevantDr. Busti reviews selective serotonin reuptake inhibitors (SSRIs)—their mechanism, first-line indications, key side effects, and clinical pearls. Learn why SSRIs are widely used for depression and anxiety, how to avoid pitfalls like QT prolongation and drug interactions, and what to monitor to optimize patient care.Access bonus materials and downloads at https://thisiswhy.healthFind resources for this topic at https://www.thisiswhy.health/topics/pharmacology-review-tca-tricyclic-antidepressantsDisclaimer: This content is for educational purposes only and is not intended to provide medical advice, diagnosis, or treatment. Always seek the advice of your physician or...
2025-10-0734 minThis Is Why with Dr. BustiSNRI Antidepressants: Pharmacology Made Easy & Clinically RelevantDiscover serotonin-norepinephrine reuptake inhibitors (SNRIs)—safe, effective antidepressants for depression, anxiety, and pain syndromes. In this episode, you’ll learn:- How SNRIs work in the brain and differ from SSRIs, TCAs, and MAOIs- Key medications: venlafaxine, desvenlafaxine, duloxetine, milnacipran, levomilnacipran- Important side effects, including blood pressure changes and SIADH in older adults- Tips for safe switching, monitoring, and counseling patientsCompanion tables (indications, mechanisms, PK/PD, side-effect grid, and monitoring prompts) are available for download and teaching at https://www.thisiswhy.health/topics/pharmacology-review-snri-antidepressantsDisclaimer: This...
2025-10-0729 minThis Is Why with Dr. BustiAtypical Antidepressants: Pharmacology Made Easy & Clinically RelevantDr. Busti explores the atypical antidepressants—bupropion, mirtazapine, trazodone, vilazodone, and vortioxetine. Learn how these agents differ from SSRIs/SNRIs, when to use them, and how their unique side effect profiles can actually guide therapy.Access tables, visuals, and playlists for this episode at https://www.thisiswhy.health/topics/pharmacology-review-atypical-antidepressantsDisclaimer: This content is for educational purposes only and is not intended to provide medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical ad...
2025-10-0736 minThis Is Why with Dr. BustiMAOI Antidepressants: Pharmacology Made Easy & Clinically RelevantDr. Busti breaks down monoamine oxidase inhibitors (MAOIs)—where they still fit in modern care, how they work, and how to use them safely.In this episode you’ll learn:Why MAOIs remain relevant for treatment-resistant depressionHow irreversible MAO-A/B inhibition elevates serotonin, norepinephrine, and dopaminePractical washout rules (why 14 days after MAOI, generally 7 days before starting an MAOI; longer with fluoxetine)High-yield differences (e.g., selegiline transdermal for depression vs. oral formulations for Parkinson’s disease)Key drug–drug risks (serotonergic agents, certain opioids like tramadol, linezolid/methylene blue)Tyramine-containing foods and counseling to prevent hypertensive crisis
2025-10-0737 minThis Is Why with Dr. BustiProton Pump Inhibitors (PPI): Pharmacology Made Easy & Clinically RelevantDr. Busti reviews Proton Pump Inhibitors (PPIs)—how they work, why they outperformed H2 blockers, key clinical uses, and important risks. From GERD to GI bleeds, learn the why behind PPIs so you can apply them safely in practice.Access tables, visuals, and playlists for this video at https://www.thisiswhy.health/topics/pharmacology-review-proton-pump-inhibitors-ppiDisclaimer: This content is for educational purposes only and is not intended to provide medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Ne...
2025-10-0748 minThis Is Why with Dr. BustiInhaled Corticosteroids: Pharmacology Made Easy & Clinically RelevantA practical pharmacology review of inhaled corticosteroids (ICS) in asthma and COPD. Dr. Busti explains why ICS are first-line therapy in asthma, their selective role in COPD, key mechanisms, dosing strategies, side effects, and patient counseling points to improve adherence and outcomes.Access downloads for this episode at https://www.thisiswhy.health/topics/pharmacology-review-inhaled-corticosteroids-asthma-copdDisclaimer: This content is for educational purposes only and is not intended to provide medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition...
2025-10-0744 minThis Is Why with Dr. BustiPotassium-Competitive Acid Blockers (PCAB): Pharmacology Made Easy & Clinically RelevantIn this episode of This Is Why, Dr. Busti unpacks the pharmacology and clinical relevance of the potassium-competitive acid blocker (P-CAB) class—featuring vonoprazan, the newest option in acid suppression therapy.You’ll learn how P-CABs compare to H₂ receptor antagonists and proton pump inhibitors (PPIs) in terms of mechanism, onset, and duration of acid control. Dr. Busti explains the unique pharmacodynamic and pharmacokinetic properties that make vonoprazan a valuable alternative for patients who do not adequately respond to PPIs.The discussion connects the drug’s molecular action a...
2025-10-0737 minThis Is Why with Dr. BustiCognitive Resonance vs Dissonance: Turning Gaps into GrowthCognitive dissonance—the moment we realize we don’t know something we should—can either hinder or grow us. In this episode, Dr. Busti explains how understanding and managing dissonance within the Evidence-Based Medicine framework strengthens humility, reflection, and better patient care. Learn to turn uncertainty into growth and develop true cognitive resonance.Access bonus materials and downloads at https://thisiswhy.healthDisclaimer: This content is for educational purposes only and is not intended to provide medical advice, diagnosis, or treatment. Always seek the advice of your physician or other...
2025-10-0618 minThis Is Why with Dr. BustiEBM in Real Life: When I Didn’t Know the “Why” (Deep Dive)In this personal reflection, Dr. Busti shares a formative moment of cognitive dissonance that reshaped his approach to evidence-based medicine. When a simple question exposed a knowledge gap, it sparked a lifelong commitment to understanding the “why” behind clinical decisions—and to teaching with honesty and humility.Access bonus materials and downloads at https://thisiswhy.healthDisclaimer: This content is for educational purposes only and is not intended to provide medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medica...
2025-10-0615 minThis Is Why with Dr. BustiThyroid Hormone Replacement: Pharmacology Made Easy & Clinical RelevantLevothyroxine is first-line for hypothyroidism, but getting it right requires precision. In this episode, Dr. Busti explains the TSH–T4–T3 feedback loop, why T4 is preferred over T3 or desiccated thyroid, and how half-life and protein binding shape dosing and monitoring. We cover steady-state timing (6–8 weeks), dose step sizes, manufacturer switches, and how food and cation supplements (calcium, iron, magnesium) alter absorption. You’ll also learn how anticonvulsants, rifampin, beta-blockers, steroids, and amiodarone affect levels or peripheral conversion.Special populations receive focused guidance: immediate dose increases in pregnancy, careful titration in cardiovascular disease, and intentional TSH suppress...
2025-10-0644 minThis Is Why with Dr. BustiStep 4 and 5 Apply and Assess: Where Evidence Meets UnderstandingThe final two steps of Evidence-Based Medicine—Apply and Assess—focus on turning knowledge into better patient outcomes. Dr. Busti explains how to apply evidence to real-world practice, integrate patient preferences, and assess the impact of your decisions to continually improve care. Discover how adapting your approach over time creates a more patient-centered, evidence-driven practice.Access bonus materials and downloads at https://thisiswhy.healthDisclaimer: This content is for educational purposes only and is not intended to provide medical advice, diagnosis, or treatment. Always seek the advice of your phys...
2025-10-0616 minThis Is Why with Dr. BustiStep 3 Appraise the Evidence: Where Evidence Meets UnderstandingStep 3 of Evidence-Based Medicine focuses on appraising the evidence. Dr. Busti explains how to systematically evaluate research using validated critical appraisal tools (CATs), detect bias, and interpret the quality of data before applying it to patient care. Learn to distinguish strong evidence from weak studies and develop a reliable, reproducible process for evidence-based decision-making.Access bonus materials and downloads at https://thisiswhy.healthDisclaimer: This content is for educational purposes only and is not intended to provide medical advice, diagnosis, or treatment. Always seek the advice of your physician...
2025-10-0621 minThis Is Why with Dr. BustiStep 1 Ask a Clinical Question: Where Evidence Meets UnderstandingEvidence-Based Medicine (EBM) has been shaping clinical decision-making for more than three decades. In this episode, Dr. Busti walks through Step 1 of the 5 A’s — Ask, focusing on how to craft clear, answerable clinical questions that drive better evidence searches and stronger patient care decisions.You’ll learn the difference between background and foreground questions, explore the structure of PICO (Population, Intervention, Comparison, Outcome), and understand how extensions like PICOT and PICOTS add precision by incorporating time and setting. Using practical clinical examples—from asthma and hypertension to acute coronary syndromes—Dr. Busti demonstrates how well-formed questions save time...
2025-10-0627 minThis Is Why with Dr. BustiStep 2 Acquire the Best Evidence: Where Evidence Meets UnderstandingStep 2 of the EBM process is all about how to acquire evidence efficiently. Dr. Busti explains how to turn your PICO question into an effective search strategy, use Boolean logic and MESH terms, and select the best databases for your clinical question. Learn to differentiate primary, secondary, and tertiary literature and find the most relevant evidence quickly without missing key studies.Access bonus materials and downloads at https://thisiswhy.healthDisclaimer: This content is for educational purposes only and is not intended to provide medical advice, diagnosis, or treatment. Always seek...
2025-10-0638 minThis Is Why with Dr. BustiThiazide Diuretics: Pharmacology Made Easy & Clinical RelevantThiazide diuretics have been essential in managing hypertension and remain one of the most widely prescribed drug classes today. But their value becomes clearer when you understand the “why.”In this episode, Dr. Busti explains the mechanism of thiazides at the distal convoluted tubule, how this drives sodium handling, and why their clinical effects differ from loop diuretics. We cover the key agents — hydrochlorothiazide, chlorthalidone, indapamide, and metolazone — and discuss their use in hypertension, edema, and special populations.Practical insights include why chlorthalidone often has stronger evidence than HCTZ, why higher HCTZ doses don’t yield more...
2025-10-061h 03This Is Why with Dr. BustiLoop Diuretics: Pharmacology Made Easy & Clinically RelevantMRAs—spironolactone, eplerenone, and finerenone—do far more than nudge blood pressure. They improve outcomes in heart failure, offer targeted benefits in CKD with T2D, and play a unique role in cirrhosis-related ascites. In this focused review, Dr. Busti walks through the why behind the what: aldosterone receptor blockade, tissue selectivity (kidney vs heart), and how those differences drive real-world choices, dosing, and safety.We compare agents head-to-head, unpack RAAS physiology, and translate it into exam-ready pearls and bedside judgment—covering hyperkalemia risk, gynecomastia, CYP3A4 interactions, ACEi/ARB combinations, and how to counsel on potassium-containing salt s...
2025-10-061h 12This Is Why with Dr. BustiMineralocorticoid Receptor Antagonists: Pharmacology Made Easy & Clinically RelevantMRAs—spironolactone, eplerenone, and finerenone—do far more than nudge blood pressure. They improve outcomes in heart failure, offer targeted benefits in CKD with T2D, and play a unique role in cirrhosis-related ascites. In this focused review, Dr. Busti walks through the why behind the what: aldosterone receptor blockade, tissue selectivity (kidney vs heart), and how those differences drive real-world choices, dosing, and safety.We compare agents head-to-head, unpack RAAS physiology, and translate it into exam-ready pearls and bedside judgment—covering hyperkalemia risk, gynecomastia, CYP3A4 interactions, ACEi/ARB combinations, and how to counsel on potassium-containing salt s...
2025-10-061h 01This Is Why with Dr. BustiH2 Receptor Antagonist Antacids (H2RA): Pharmacology Made Easy & Clinically RelevantH₂ receptor antagonists like famotidine and cimetidine have been around for decades, but they still play an important role in managing GERD, dyspepsia, ulcers, and even acute GI bleeding. In this episode, Dr. Busti reviews the history, pharmacology, and clinical relevance of this class, including the withdrawal of ranitidine.You’ll learn how H₂ blockers fit into the larger category of antacid therapy, why they’re effective for mild cases but limited in long-term control, and how tolerance can reduce effectiveness. Cimetidine’s drug interaction profile is explored in detail, including CYP450 effects and alcohol metabolism. Practical dosing con...
2025-10-0642 minThis Is Why with Dr. BustiWelcome to This is Why with Dr. BustiIn this introductory episode of This Is Why, Dr. Busti shares the powerful story behind the creation of the podcast — and the mission driving it. With over 30 years of experience spanning nursing, pharmacy, medicine, and education, Dr. Busti offers a rare 360-degree perspective on healthcare.He discusses the common gap in medical training: being taught what to do and how to do it, but not always why. Through his own journey — from the ICU and emergency department to academic medicine and beyond — Dr. Busti explains how understanding the “why” transforms clinical decision-making, patient outcomes, and professional confidence.Liste...
2025-10-0605 min
Medication TalkBiosimilars in ActionListen in as we discuss considerations, challenges, and strategies related to the use and switching of biosimilars in clinical practice. You’ll hear communication tips to address patient and prescriber concerns as well as operational considerations for integrating biosimilars into practice. Special guests:Bharati Bhardwaja, PharmD, BCPS, LSSBBRheumatology Clinical Pharmacy SpecialistKaiser Permanente ColoradoMegan May, PharmD, BCOP, FHOPA, FAPOClinical Oncology Pharmacy SpecialistBaptist Health Lexington/Hamburg Cancer Care CenterYou’ll also hear practical advice from TRC’s Editorial Advisory Board member:Craig D. Williams, PharmD, FNLA, BCPSClinical Professor of Pharmacy PracticeOregon Health and Science...
2025-10-0131 minThis Is Why with Dr. BustiWhy EBM Is So Hard - And Why It MattersEvidence-Based Medicine (EBM) is a cornerstone of clinical training, but why is it so difficult to practice and teach consistently? In this deep dive, Dr. Busti unpacks the foundation of EBM, the five A’s, and why application often falls short in practice. Drawing from his training at Oxford and years of teaching across medicine, pharmacy, and nursing, he highlights misconceptions, barriers, and practical strategies to bridge the gap between evidence, education, and patient care.This episode also uses a real-world case example—the ISIS-2 trial of aspirin in acute myocardial infarction—to illustrate how evidence should be und...
2025-09-2938 minThis Is Why with Dr. BustiWhat is EBM & EBM Terminology: Where Evidence Meets UnderstandingIn this kickoff episode on Evidence-Based Medicine (EBM), Dr. Busti explains what EBM is—and what it isn’t. You’ll learn why the classic Venn diagram (evidence, expertise, and patient factors) matters, and how the "Five A’s"—Ask, Acquire, Appraise, Apply, Assess—create a practical framework for clinical decision-making. We also unpack related terms like evidence-based practice, practitioner, and expert, showing how they fit together and why balance between literature, training, and patient preferences is essential. Perfect for students and early-career clinicians ready to ground their practice in the why behind the how.Access the video plus b...
2025-09-2928 min
The Bull of Wall Street#41 - Dr. Matthew Schwartz, MD and Dr. Thomas Dayspring, MD, FACP, FNLA on Cancer Innovation, Cardiovascular Disease Prevention, and What Everyone Needs to Know (recorded 09/15/25)Health is wealth, and as advisors the impact we make extends beyond portfolios. In this two-part episode, Jimmy Lee first sits down with his good friend Dr. Matthew Schwartz, radiation oncologist and UNLV faculty member, to explore how proteomics is changing cancer treatment. Then Dr. Thomas Dayspring, one of the world’s foremost educators on lipids and mentor to Dr. Peter Attia, explains why cardiovascular disease remains the number one preventable cause of death, plus the simple blood tests and treatments that can save lives.Disclaimer: This episode is for informational purposes only and does not constitute medical ad...
2025-09-151h 43Medication TalkMeds After Acute Coronary SyndromeListen in as our expert panel discusses the latest recommendations for managing medications after heart attacks and other cardiac events. You’ll hear our panelists review which antiplatelets to use, the optimal blood pressure meds, and the role of statin and non-statin cholesterol meds.Special guests:Danielle Blais, PharmD, FCCP, BCCP, BCPSCardiology Lead Specialty Practice PharmacistRichard M. Ross Heart HospitalThe Ohio State University Wexner Medical CenterJoel C. Marrs, PharmD, MPH., BCACP, BCCP, BCPS, FAHA, FASHP, FCCP, FNLAProfessor and Coordinator of Clinical OutreachThe University of Tennessee Health Science CenterDepartment of Clinical Pharmacy & Translational ScienceYou’ll also...
2025-09-0132 minMedication TalkAntidepressant InsightsListen in as our expert panel discusses practical considerations for starting and optimizing antidepressants for treating depression and anxiety. You’ll listen to panelists cover various aspects of antidepressant use, such as serotonin syndrome, QT prolongation, and weight gain concerns.Special guests:Tammie Lee Demler, BS, PharmD, MBA, BCGP, BCPP Director of Pharmacy and Residency Programs, New York State Office of Mental Health State University of New York at Buffalo School of Pharmacy and Pharmaceutical Sciences Sarah E. Grady, PharmD, BCPS, BCPPProfessor, Drake University College of Pharmacy and Health SciencesClinical Pharmacist, Inpatient Behavioral Health Unit, Broadlawns Medica...
2025-07-0138 minMedication TalkMeds for Alzheimer DementiaListen in as our expert panel discusses medications for the treatment of Alzheimer dementia. They'll review the risks and benefits of cholinesterase inhibitors, memantine, and the anti-amyloid monoclonal antibodies. And you’ll hear strategies for managing behavioral and psychological symptoms of dementia. Special guests:Tatyana Gurvich, PharmD, BCGP, APhAssociate Professor of Clinical PharmacyMann USC School of PharmacyUCI Senior Health CenterCandace Pierce, DNP, RN, CNE, COINurse Educator, Nurse Planner, and Healthcare Leader, Colibri HealthcareDarlene Moyer, MD, FAAFPAssociate Director, HonorHealth Family Medicine Residency ProgramAssociate Professor of Clinical Practice – SOMME – Arizona State UniversityClinical Associate Professor – University of Arizona College of Medicine...
2025-06-0134 minMedication TalkMedications for Opioid Use DisorderListen in as our expert panel discusses medications for management of opioid use disorder. They’ll review strategies to optimize buprenorphine use and clarify the role of methadone and naltrexone.Special guest:Tyler J. Varisco, PharmD, PhDUniversity of Houston College of Pharmacy Assistant Professor, Department of Pharmaceutical Health Outcomes and PolicyAssistant Director, The PREMIER CenterYou’ll also hear practical advice from panelists on TRC’s Editorial Advisory Board:Stephen Carek, MD, CAQSM, DipABLM, Clinical Associate Professor of Family Medicine for the Prisma Health/USC School of Medicine Greenville Family Medicine Residency Program at the Uni...
2025-05-0137 minMedication TalkBronchitis and Pneumonia TreatmentIn this episode, listen in as our expert panel digs into identifying and treating acute bronchitis and community-acquired pneumonia. They’ll discuss when antibiotics are appropriate, which antibiotics to use, and other management tips.You’ll also hear practical advice from panelists on TRC’s Editorial Advisory Board:Stephen Carek, MD, CAQSM, DipABLM, Program Director for the Prisma Health/USC School of Medicine Greenville Family Medicine Residency Program and Clinical Associate Professor at the University of South Carolina School of Medicine, GreenvilleAndrea Darby Stewart, MD, Associate Director, Honor Health Family Medicine Residency Program and Clinical Professor of Fam...
2025-03-0134 minMedication TalkAsthma and COPD TreatmentSpecial guest Lori A. Wilken, PharmD, FCCP, BCACP, NCTTP, AE-C, Clinical Assistant Professor in the Department of Pharmacy Practice at the University of Illinois, Chicago, joins us to talk about Asthma and COPD treatment.Listen in as we discuss answers to your big questions about treatment of asthma and COPD. You’ll also hear practical advice from panelists on TRC’s Editorial Advisory Board:Stephen Carek, MD, CAQSM, DipABLM, Clinical Assistant Professor of Family Medicine, Prisma Health/USC-SOMG Family Medicine Residency Program at the USC School of Medicine GreenvilleAndrea Darby Stewart, MD, Assoc...
2024-10-0135 minMedication TalkPrecepting: Helping Learners SucceedIn this episode, listen in as our expert panelists discuss tips for creating successful learning experiences for students and residents. We’ll review various teaching tools and summarize strategies for incorporating learners into your practice. We’ll also discuss different approaches for providing meaningful feedback and managing challenging situations with learners.Our panel for this conversation includes: Andrea Darby Stewart, MD; Associate Director, Honor Health Family Medicine Residency Program; Clinical Professor of Family, Community & Occupational Medicine, University of Arizona College of Medicine – PhoenixMary Franks, MSN, APRN-FPA, FNP-C; Nurse Planner, NetCE; Adjunct Professor, Bradley University; Nurse Practitioner, Carle He...
2024-09-0147 minMedication TalkManaging Chronic Coronary DiseaseSpecial guest Dave L. Dixon, PharmD, FACC, FAHA, FCCP, FNLA, BCACP, CDCES, CLS, the Nancy L. and Ronald H. McFarlane Professor of Pharmacy and Chair of the Department of Pharmacotherapy & Outcomes Science at the Virginia Commonwealth University School of Pharmacy, joins us to talk about chronic coronary disease.Listen in as he discusses the management of chronic coronary disease with a focus on the new American College of Cardiology/American Heart Association guidelines.You’ll also hear practical advice from panelists on TRC’s Editorial Advisory Board:Anthony A. Donato, Jr...
2023-11-0133 min
Obesity: A DiseaseEpisode 87: Article Review: Obesity, Diabetes Mellitus, and Cardiometabolic Risk with Dr. Bindlish, Part 2 of 3In this episode, Obesity Medicine Association (OMA) Chief Science Officer, Harold Bays, MD, FOMA, FTOS, FACC, FNLA, FASPC interviews Shagun Bindlish, MD. Our experts discuss a series of clinical practice statements recently published in ‘Obesity Pillars’, for which Dr. Bindlish was a co- author. Obesity Pillars is the official Gold Open Access journal of the Obesity Medicine Association, available exclusively online.
In our article review podcasts, we carefully select articles from the latest version of Obesity Pillars, which is devoted to the publication of clinical and evidence-based research for physicians, nurse practitioners, physician assistants and other health care...
2023-08-2818 minObesity: A DiseaseEpisode 85: Article Review: Obesity, Diabetes Mellitus, and Cardiometabolic Risk with Dr. Bindlish, Part 1 of 3In this episode, Obesity Medicine Association (OMA) Chief Science Officer, Harold Bays, MD, FOMA, FTOS, FACC, FNLA, FASPC interviews Shagun Bindlish, MD. Our experts discuss a series of clinical practice statements recently published in ‘Obesity Pillars’, for which Dr. Bindlish was a co- author. Obesity Pillars is the official Gold Open Access journal of the Obesity Medicine Association, available exclusively online.
In our article review podcasts, we carefully select articles from the latest version of Obesity Pillars, which is devoted to the publication of clinical and evidence-based research for physicians, nurse practitioners, physician assistants and other health care...
2023-08-0717 min
Lipid InsightsS4E2: Nutrition Interventions for Adults with DyslipidemiaAlan Brown, MD, FNLA talks with Carol F. Kirkpatrick, PhD, MPH, RDN, CLS, FNLA and Kevin C Maki, PhD, CLS, FNLA, FTOS, FACN to discuss Nutrition Interventions for Adults with Dyslipidemia.
2023-07-3136 minObesity: A DiseaseEpisode 83: Article Review: Obesity, Diabetes Mellitus, and Cardiometabolic Risk, Part 3 of 3In this episode, Obesity Medicine Association (OMA) Chief Science Officer, Harold Bays, MD, FOMA, FTOS, FACC, FNLA, FASPC interviews Tiffany Lowe-Clayton, DO. Our experts discuss a series of clinical practice statements recently published in Obesity Pillars, for which Dr. Lowe-Clayton was a co- author. Obesity Pillars is the official Gold Open Access journal of the Obesity Medicine Association, available exclusively online.
In our article review podcasts, we carefully select articles from the latest version of Obesity Pillars, which is devoted to the publication of clinical and evidence-based research for physicians, nurse practitioners, physician assistants and other health...
2023-05-1816 minObesity: A DiseaseEpisode 81: Article Review: Obesity, Diabetes Mellitus, and Cardiometabolic Risk, Part 2 of 3In this episode, Obesity Medicine Association (OMA) Chief Science Officer, Harold Bays, MD, FOMA, FTOS, FACC, FNLA, FASPC interviews Tiffany Lowe-Clayton, DO. Our experts discuss a series of clinical practice statements recently published in Obesity Pillars, for which Dr. Lowe-Clayton was a co-author. Obesity Pillars is the official Gold Open Access journal of the Obesity Medicine Association, available exclusively online.
In our article review podcasts, we carefully select articles from the latest version of Obesity Pillars, which is devoted to the publication of clinical and evidence-based research for physicians, nurse practitioners, physician assistants and other health care...
2023-04-2615 minObesity: A DiseaseEpisode 78: Article Review: Obesity, Diabetes Mellitus, and Cardiometabolic RiskIn this episode, Obesity Medicine Association (OMA) Chief Science Officer, Harold Bays, MD, FOMA, FTOS, FACC, FNLA, FASPC interviews Tiffany Lowe-Clayton, DO. Our experts discuss a series of clinical practice statements recently published in ‘Obesity Pillars’, for which Dr. Lowe-Clayton was a co- author. Obesity Pillars is the official Gold Open Access journal of the Obesity Medicine Association, available exclusively online.
In our article review podcasts, we carefully select articles from the latest version of Obesity Pillars, which is devoted to the publication of clinical and evidence-based research for physicians, nurse practitioners, physician assistants and other health care...
2023-03-2421 minObesity: A DiseaseEpisode 73: Article Reviews: Clinical Practice Statements for the Management of Obesity – Nutrition and Physical Activity, Part 2 of 2: Body CompositionOMA Chief Science Officer, Harold Bays, MD, FOMA, FTOS, FACC, FNLA, FASPC interviews Karli Burridge, PA-C, MMS, FOMA about the Obesity Medicine Association (OMA) Clinical Practice Statement (CPS) for which she was first author, titled 'Nutrition and Physical Activity'. The CPS serves as a flexible guide for providers seeking to create or improve an obesity medicine program. Topics include personal history documentation; laboratory procedures; components of energy expenditure; non-exercise activity thermogenesis (NEAT); accurately assessing and understanding body composition; body fat cut-off levels and the inclusion of a "pre-obesity" category.
In our article review podcasts, we have carefully...
2022-12-1620 minObesity: A DiseaseEpisode 72: Article Reviews: Clinical Practice Statements for the Management of Obesity – Nutrition and Physical Activity, Part 1 of 2: Effective Patient Documentation; Electronic Medical Records (EMR’s) and Energy ExpenditureOMA Chief Science Officer, Harold Bays, MD, FOMA, FTOS, FACC, FNLA, FASPC interviews Karli Burridge, PA-C, MMS, FOMA about the Obesity Medicine Association (OMA) Clinical Practice Statement (CPS) for which she was first author, titled 'Nutrition and Physical Activity'. The CPS serves as a flexible guide for providers seeking to create or improve an obesity medicine program. Topics include personal history documentation; laboratory procedures; components of energy expenditure; non-exercise activity thermogenesis (NEAT); accurately assessing and understanding body composition; body fat cut-off levels and the inclusion of a "pre-obesity" category.
In our article review podcasts, we have carefully...
2022-12-1525 minLipid InsightsS3E2: Statin Underuse PersistenceAlan Brown, MD, FNLA talks with Mary Katherine Cheeley, PharmD, FNLA about the persistence of statin underuse i practice.
2022-12-0538 minObesity: A DiseaseEpisode 71: Article Reviews: Clinical Practice Statements for the Management of Obesity – Cancer and Obesity; Part 2 of 2OMA Chief Science Officer, Harold Bays, MD, FOMA, FTOS, FACC, FNLA, FASPC interviews Ethan Lazarus, MD, FOMA, AMA Delegate about the Obesity Medicine Association (OMA) Clinical Practice Statement for which he was first author, titled 'Cancer and Obesity'. The CPS serves as a flexible guide for providers seeking to create or improve an obesity medicine program.
Today's topics include the management and care of patients with obesity following a cancer diagnosis; the need for aggressive treatment of obesity using behavioral, medical and surgical strategies; the benefits of weight loss in cancer patients with obesity; and the devastating...
2022-09-0918 minObesity: A DiseaseEpisode 70: Article Reviews: Clinical Practice Statements for the Management of Obesity – Cancer and Obesity; Part 1 of 2OMA Chief Science Officer, Harold Bays, MD, FOMA, FTOS, FACC, FNLA, FASPC interviews Ethan Lazarus, MD, FOMA, AMA Delegate about the Obesity Medicine Association (OMA) Clinical Practice Statement for which he was first author, titled 'Cancer and Obesity'. The CPS serves as a flexible guide for providers seeking to create or improve an obesity medicine program.
Today's topics include the complex relationship between cancer and obesity; how the steep decline of nicotine use over the past 30 years can inform us regarding possibilities for obesity management and care; and the nature of fat as a metabolically, hormonally active...
2022-09-0920 minObesity: A DiseaseEpisode 69: Article Reviews: Clinical Practice Statements for the Management of Obesity – Cancer and Obesity; Full PodcastOMA Chief Science Officer, Harold Bays, MD, FOMA, FTOS, FACC, FNLA, FASPC interviews Ethan Lazarus, MD, FOMA, AMA Delegate about the Obesity Medicine Association (OMA) Clinical Practice Statement for which he was first author, titled 'Cancer and Obesity'. The CPS serves as a flexible guide for providers seeking to create or improve an obesity medicine program.
Today's topics include the complex relationship between cancer and obesity; how the steep decline of nicotine use over the past 30 years can inform us regarding possibilities for obesity management and care; and the nature of fat as a metabolically, hormonally active...
2022-09-0832 minMedication TalkStatin IntoleranceTRC Editor, Dr. Lori Dickerson, PharmD, FCCP talks with Joseph Saseen, PharmD, FCCP, FNLA, Associate Dean for Clinical Affairs, Professor, Department of Clinical Pharmacy and Professor, Department of Family Medicine from the Skaggs School of Pharmacy and Pharmaceutical Sciences at the University of Colorado Anschutz Medical Campus about managing statin intolerance. Listen in as they discuss how to evaluate statin-associated muscle pain...and review strategies to help patients take a statin successfully. You’ll also hear practical advice from panelists on TRC’s Editorial Advisory Board:Andrea Darby Stewart, MD, Associ...
2022-09-0132 min
South African Border WarsEpisode 48 – Russian specialists set up anti-aircraft missiles and Special Forces ops accelerate across the cutlineThe Russians were increasing their support for the MPLA in Luanda and one of those who arrived was Vladimir Vasilievich Kostrachenkov. He helped establish the Pechora Anti-Aircraft system between 1979 and 1981 in the south of Angola and published some of his thoughts in a book called Bush War, the Road to Cuito Cuanavale. While most of this book is about the major battles that took place later around Cuito, Kostrachenkov’s explanation of what happened in the south in the very 80s is important for us at this juncture.
It was his second tour of duty of Angola – his first was...
2022-02-2723 minSouth African Border WarsEpisode 18 – The Battle of Ebo - the first major defeat for the SADF during Operation SavannahThis is episode 18 and folks back home were in for a bit of a shock. The invasion of Angola by the SADF during Operation Savannah had been an exercise in support of both Unita and the FNLA – but the government had said that the South Africans were merely technical support.
The reality was hundreds of SADF troops were directly involved in the fighting – and had fought all the way to south of the capital Luanda. This was almost a thousand kilometers inside Angola. As we heard last episode, by the end of November a group of liaison officers and...
2021-06-2819 minSouth African Border WarsEpisode 17 – The SAS Steyn’s role in the remarkable evacuation from the beach at AmbrizetteThis is episode 17 and we’re approaching the end of Operation Savannah which had started out so well but was rapidly turning into a strategic nightmare for the South Africans.
One of the fastest mechanised invasions since World War Two had resulted in the SADF now deep into Angola – and in the case of Brigadier Roos who was a liaison officer based in Ambriz with the FNLA – he was cut off on the coast to the north of the capital Luanda.
IT was mid-November 1975 and the MPLA and Cubans were starting to move determined to rid the co...
2021-06-2119 minSouth African Border WarsEpisode 16 – Luanda’s “Death Road” leaves the FNLA in tatters and the CIA decides to up and offThis is episode 16 and we’re covering Operation Savannah which took place between October and December 1975.
That was the invasion of southern Angola by the South African Defence Force in response to the outbreak of a civil war in the country involving the three main independence movements that had fought against Portuguese colonial rule.
These were the MPLA, Unita and the FNLA. Our focus in this episode shifts in a while to the FNLA’s assault on the Capital Luanda.
But first an update about the SADF.
Brigadier Schoeman who was in char...
2021-06-1418 min
iUniverseBrian Scott Edwards, MD, FNLA, S. T. Byra and Leo CauzilloiUniverse Radio order of interviews for show: 3:00-4:00PM EST 1. “The Chronic Disease of Obesity: How Sponge Syndrome Causes Repeated Weight Gain”; by Brian Scott Edwards, MD, FNLA 2. “One and One Is One: The Beginning”; by S. T. Byra 3. “They are Not Alone: Mythology or History”; by Leo Cauzillo
2019-06-1047 min
The Peter Attia DriveTom Dayspring, M.D., FACP, FNLA – Part V of V: Lp(a), inflammation, oxLDL, remnants, and moreIn this five-part series, Thomas Dayspring, M.D., FACP, FNLA, a world-renowned expert in lipidology, and one of Peter's most important clinical mentors, shares his wealth of knowledge on the subject of lipids. In Part V, Peter and Tom talk about inflammation, endothelial health, and oxidative stress as they pertain to cardiovascular disease, and our attempts to monitor them using biomarkers. They also discuss a couple of very important risk factors that too few people (and doctors) know about. Tom closes the five-part series with a tragic story about his good friend that is likely all-too-common for many practicing...
2018-10-191h 29
The Peter Attia DriveTom Dayspring, M.D., FACP, FNLA – Part IV of V: Statins, ezetimibe, PCSK9 inhibitors, niacin, cholesterol and the brainIn this five-part series, Thomas Dayspring, M.D., FACP, FNLA, a world-renowned expert in lipidology, and one of Peter's most important clinical mentors, shares his wealth of knowledge on the subject of lipids. In Part IV, Peter and Tom review the history and current use of drugs to prevent cardiovascular disease. They also discuss why some drugs appear to be more effective than others, an in-depth conversation about niacin, cholesterol and brain health, and the futility of using CKs (creatinine kinase) and liver function tests to identify adverse effects in statins, to name a few topics in this episode.
2018-10-182h 00
The Peter Attia DriveTom Dayspring, M.D., FACP, FNLA – Part III of V: HDL, reverse cholesterol transport, CETP inhibitors, and apolipoproteinsIn this five-part series, Thomas Dayspring, M.D., FACP, FNLA, a world-renowned expert in lipidology, and one of Peter's most important clinical mentors, shares his wealth of knowledge on the subject of lipids. In Part III, Peter and Tom dig into HDL, why "reverse cholesterol transport" is a lot more nuanced than what most of us are taught, lipid transport, apolipoproteins, and more. In addition, this episode highlights the complexity of HDL and a discussion about the CETP inhibitor trials. We discuss: Reverse cholesterol transport [1:40]; Lipid transportation, apolipoproteins, VLDL, IDL, and LDL particles [11:00]; Remnant lipoproteins and...
2018-10-171h 04
The Peter Attia DriveTom Dayspring, M.D., FACP, FNLA – Part II of V: Lipid metrics, lipid measurements, and cholesterol regulation In this five-part series, Thomas Dayspring, M.D., FACP, FNLA, a world-renowned expert in lipidology, and one of Peter's most important clinical mentors, shares his wealth of knowledge on the subject of lipids. In Part II, Tom provides a 101 on lipids and lipoproteins. Tom and Peter also discuss the history and techniques used to measure lipoproteins, and more. We discuss: Lipoprotein basics [1:30]; Gofman and the ultracentrifuge [5:15]; Lipoprotein structure, function, metabolism [6:45]; Lipoprotein and cholesterol measurement, and NMR technology [15:15]; LDL-C vs LDL-P and apoB [30:45]; Sterols and cholesterol synthesis [39:45]; and More. Learn more at www.PeterAttiaMD.com Connect with Peter on...
2018-10-161h 26
The Peter Attia DriveThomas Dayspring, M.D., FACP, FNLA – Part I of V: an introduction to lipidologyIn this five-part series, Thomas Dayspring, M.D., FACP, FNLA, a world-renowned expert in lipidology, and one of Peter's most important clinical mentors, shares his wealth of knowledge on the subject of lipids. Part I serves as an introduction to Tom, his work, and an overview of lipid terminology. We discuss: Tom's recent and remarkable physical transformation [6:30]; The moving stories behind Tom's obsessions: firefighting, hockey, and, of course, lipids [20:30]; Tom's medical background [39:30]; Producing some of the most accessible diagrams on lipids [50:00]; What are the different kinds of lipids, what do they do, and how are they...
2018-10-151h 14
Lipid LuminationsCardiovascular Risk Reduction in the Elderly: Best Lipid Strategies
Host: Alan S. Brown, MD, FACC, FAHA, FNLA
Guest: Joyce Ross, MSN, CRNP, CS, CLS, FNLA, FPCNA
Host Dr. Alan Brown welcomes Joyce Ross, MSN, CRNP, FNLA, President-Elect of the National Lipid Association. Joyce serves as a consultative education specialist in cardiovascular risk intervention with the University of Pennsylvania Health System. Their discussion focuses on lipid management to reduce atherosclerotic cardiovascular disease (ASCVD) risk in elderly patient populations. Thhis interview was recorded live at the National Lipid Association in San Diego, California for the 2016 Spring Clinical Lipid Update.
2016-05-0916 minLipid LuminationsCardiovascular Risk Reduction in the Elderly: Best Lipid Strategies
Host: Alan S. Brown, MD, FACC, FAHA, FNLA
Guest: Joyce Ross, MSN, CRNP, CS, CLS, FNLA, FPCNA
Host Dr. Alan Brown welcomes Joyce Ross, MSN, CRNP, FNLA, President-Elect of the National Lipid Association. Joyce serves as a consultative education specialist in cardiovascular risk intervention with the University of Pennsylvania Health System. Their discussion focuses on lipid management to reduce atherosclerotic cardiovascular disease (ASCVD) risk in elderly patient populations. Thhis interview was recorded live at the National Lipid Association in San Diego, California for the 2016 Spring Clinical Lipid Update.
2016-05-0900 minLipid LuminationsThe Lipidology Essentials: Making of a Specialty's Annual Summary
Host: Alan S. Brown, MD, FACC, FAHA, FNLA
Guest: Harold Bays, MD, FNLA
Dr. Alan Brown welcomes Dr. Harold Bays, President of the Southeast Lipid Association and President of the Louisville Metabolic and Atherosclerotic Research Center in Louisville, KY. Dr. Bays led a novel educational effort to provide an annual summary of clinical lipidology to readers of the Journal of Clinical Lipidology. With insightful commentaries of value to lipidologists and generalists alike, the annual summary is expected to pave new ground in the ongoing effort to keep clinicians up to date with the field.
2016-04-1800 minLipid LuminationsUpdated NLA Recommendations for African American Patients
Host: Alan S. Brown, MD, FACC, FAHA, FNLA
Guest: Keith C. Ferdinand, MD, FACC, FAHA , FASPC, FNLA, FPCNA
Host Dr. Alan Brown is joined by Dr. Keith C. Ferdinand, Professor at Tulane University School of Medicine in New Orleans, Louisiana. Dr. Ferdinand reviews the etiologies, diagnostic challenges, and management considerations for selective cardiac health issues prevalent in African American populations, from hypertension to coronary arterial calcium plaques to lipid levels. Supported by an Educational Grant from AstraZeneca.
2015-08-0300 minLipid LuminationsDyslipidemia in The Elderly: How Old is "Too Old" to Treat?
Host: Alan S. Brown, MD, FACC, FAHA, FNLA
Guest: Joyce Ross, MSN, CRNP, CS, CLS, FNLA, FPCNA
One of the most recurrent questions that cardiologists and lipidologists face in daily practice is how to best approach the elderly patient with dyslipidemia. Joining Dr. Alan Brown for special considerations in this population and guideline-based recommendations for management is Joyce Ross, certified registered nurse practitioner, clinical lipid specialist, and President-Elect of the National Lipid Association. Supported by an Educational Grant from AstraZeneca.
2015-07-2700 min
Congo LiveJames L Hope: Black Lives Matter - from Baltimore to the CongoJames L. Hope joins Congo Live! to discuss his time in the Congo and the current situation in Baltimore. He was also in the Congo in the 1960s and kept the tradition alive of supporting liberation movement on the African continent. We will also discuss current affairs in Baltimore.
Bio:
James L. Hope is the International Advisor of the African Scientific Institute (ASI). He first set foot on the African Continent in 1951 when his ship stopped in Alexandria, Egypt on its way to Beirut, Lebanon where he took up residence and attended school. Over the years Mr. Hope assisted in...
2015-05-0400 minLipid LuminationsRoles of Non-HDL Cholesterol in Risk Assessment and Treatment
Host: Alan S. Brown, MD, FACC, FAHA, FNLA
A paradigm shift in the management of lipid disorders has been witnessed of late based on evidence reviews by the AHA and the ACC. Where the clinical dogma once focused on targeting specific lipoproteins, clinicians are now trending toward using appropriate dosages of statins for lowering non-HDL cholesterol. What are the ramifications of this change in approach, and how does the NLA weigh in on recommendations for targets and goals? To address these and other questions, host Dr. Alan Brown welcomes Kevin Maki, PhD, FNLA, CLS, Chief Science Officer for...
2014-09-1600 minLipid LuminationsKeys to the Latest NLA Recommendations for Dyslipidemia Treatments
Host: Alan S. Brown, MD, FACC, FAHA, FNLA
What's the evidence for LDL and other non-HDL targets for primary and secondary prevention of heart disease? What are the comparative benefits versus toxicities of all lipid-lowering medications in clinical use? Addressing these and other questions from the standpoing of recent NLA recommendations is Kevin Maki, PhD, FNLA, CLS, Chief Science Officer for Midwest Center for Metabolic and Cardiovascular Research and Adjunct Faculty in Biostatistics and Applied Epidemiology at DePaul University, Chicago, IL. Produced in partnership with
2014-09-0900 minLipid LuminationsManagement of the Patient With Triglycerides 200-499 mg/dl.
Host: Alan S. Brown, MD, FACC, FAHA, FNLA
Guest: Carl Orringer, MD, FACC, FNLA
What are some of the causes of high triglycerides? What is the biggest health risk? And, for these patients, at what level is the risk greater for developing pancreatitis and coronary artery disease? Host Dr. Alan Brown welcomes Dr. Carl Orringer, Associate Professor of Medicine at the Cardiology Division, University of Miami Medical Center and Director of the Preventive Cardiovascular Medicine and LDL apheresis program. In this edition of Lipid Luminations, Dr. Orringer will discuss the management of the patients with triglycerides 200-499...
2014-08-2600 minLipid LuminationsWhat is the Safety of Statins in Patients with Diabetes?
Host: Alan S. Brown, MD, FACC, FAHA, FNLA
Guest: Kevin C. Maki, PhD, FNLA, CLS
At the most recent National Lipid Association (NLA) meeting, host Dr. Alan Brown welcomes Kevin Maki, PhD, FNLA, CLS, Chief Science Officer for Midwest Center for Metabolic and Cardiovascular Research and Adjunct Faculty position in Biostatistics and Applied Epidemiology at DePaul University, Chicago, IL. Drs. Brown and Maki discuss the evidence of the relationship of statin use and risk of new onset of diabetes; as well as, the relationship of statin use and the possiblity of worsening glycemia in those patients who...
2014-05-1312 minLipid LuminationsWhat is the Safety of Statins in Patients with Diabetes?
Guest: Kevin C. Maki, PhD, FNLA, CLS
Host: Alan S. Brown, MD, FACC, FAHA, FNLA
At the most recent National Lipid Association (NLA) meeting, host Dr. Alan Brown welcomes Kevin Maki, PhD, FNLA, CLS, Chief Science Officer for Midwest Center for Metabolic and Cardiovascular Research and Adjunct Faculty position in Biostatistics and Applied Epidemiology at DePaul University, Chicago, IL. Drs. Brown and Maki discuss the evidence of the relationship of statin use and risk of new onset of diabetes; as well as, the relationship of statin use and the possiblity of worsening glycemia in those patients who...
2014-05-1300 minLipid LuminationsNational Lipid Association Recommendations for Patient-Centered Management of Dyslipidemia
Guest: Carl Orringer, MD, FACC, FNLA
Guest: Kevin C. Maki, PhD, FNLA, CLS
Host: Alan S. Brown, MD, FACC, FAHA, FNLA
Guest: Harold Bays, MD, FNLA
Guest: Matthew Ito, PharmD, FNLA
Host Dr. Alan Brown is joined by an expert panel to discuss the NLA's latest draft document that will serve as recommendations to clinicians for the management of patients with dyslipidemia. The National Lipid Association's goal was to harmonize guidelines among what has been presented in the past by the ATP panel, the American College of Cardiology/American Heart Association Guidelines, and those...
2014-05-0830 minLipid LuminationsNational Lipid Association Recommendations for Patient-Centered Management of Dyslipidemia
Guest: Kevin C. Maki, PhD, FNLA, CLS
Guest: Carl Orringer, MD, FACC, FNLA
Guest: Harold Bays, MD, FNLA
Host: Alan S. Brown, MD, FACC, FAHA, FNLA
Guest: Matthew Ito, PharmD, FNLA
Host Dr. Alan Brown is joined by an expert panel to discuss the NLA's latest draft document that will serve as recommendations to clinicians for the management of patients with dyslipidemia. The National Lipid Association's goal was to harmonize guidelines among what has been presented in the past by the ATP panel, the American College of Cardiology/American Heart Association Guidelines, and those...
2014-05-0800 minLipid LuminationsObesity, Diabetes and the Metabolic Syndrome
Host: Alan S. Brown, MD, FACC, FAHA, FNLA
Guest: Kevin C. Maki, PhD, FNLA, CLS
Host Dr. Alan S. Brown is joined by Kevin C. Maki, PhD, FNLA, Chief Science Officer of Biofortis Clinical Research. Dr. Maki will review obesity, metabolic syndrome and type 2 diabetes mellitus as they are all insulin resistant states and are often characterized by atherogenic dyslipidemia or the "lipid triad" of elevated triglycerides, low HDL cholesterol and a predominance of small, dense LDL particles.
2013-02-2514 min