Shows
Inside Exercise#90 - Former WR marathoner Derek Clayton with the top researchers who've studied him over 50 yearsDr Glenn McConell chats with legendary Australian former marathon world record holder and lifelong exerciser Derek Clayton and the three top researchers who have tested him over 50 years. Derek, who is now 82 years old, broke the marathon world record in 1967 running 2:09:36 when the previous record was 2:12:11(!). Then in 1969 he ran 2:08:33 a world record which wasn’t broken until 1981. He then continued to train at a high level, especially cycling. He was VO2 max tested in 1969 by Professor David Costill, 1991 by Professor Costill, Professor Mark Hargreaves and myself then in 2022 by sports cardiologist Dr Andre La Gerche and Prof Hargreaves. Ea...
2025-04-241h 59Inside Exercise#89 - Concurrent training with Dr Tommy LundbergDr Glenn McConell chats with Dr Tommy Lundberg from the Karolinska Institute in Stockholm, Sweden. He is an expert on resistance training (RT) and has focussed on the effect of concurrent training on exercise adaptations. That is, does doing concurrent resistance and endurance training affect the responses to resistance and endurance training compared to doing either alone. His research has specifically focused on the effects of endurance training on resistance training adaptations although we also discussed the effect of resistance training on endurance training adaptations. It appears that in many people concurrent training has either no interfering effect or...
2025-02-071h 31Inside Exercise#88 - Exercise preserves muscle and metabolism during cancer with Dr Lykke SylowDr Glenn McConell chats with Associate Professor Lykke Sylow from The University of Copenhagen. She is a rising star in exercise metabolism and in particular the effect of exercise on cancer. This is the second podcast episode on exercise and cancer (See Professor Kathryn Schmitz episode #9).Remarkably she said that if you are a non-smoker your biggest risk of getting cancer is inactivity. Not clear if this is independent of obesity etc. Can associated with a reduction of insulin sensitivity and also cachexia (with the loss of muscle mass is very important). The cancer itself may cause insulin...
2024-09-291h 26Inside Exercise#87 - Exercise and sports cardiology with Professor Paul D. ThompsonDr Glenn McConell chats with Professor Paul D. Thompson who is Chief of Cardiology, Emeritus at Hartford Hospital, Hartford, CT and Professor of Medicine, Emeritus at the University of Connecticut. He has published over 500 peer reviewed journal articles, was a past President of the American College of sports medicine (ACSM) and was a impressively fast marathon runner. This is the third of a series of podcast episodes on sport cardiology (See Professor Benjamin Levine and Associate Professor Andre La Gerche’s episodes). We covered a lot of ground. There is a greater prevalence of atrial fibrillation in athletes (is it...
2024-08-152h 03Inside Exercise#86 - Can changing gait reduce running injuries with Professor Bryan HeiderscheitDr Glenn McConell chats with Professor Bryan Heiderscheit from the University of Wisconsin in USA. He is an expert on running injuries. This is the third of a series of podcast episodes on running injuries (See Professor Irene Davis’s and Associate Professor Rasmus Østergaard Nielsen’s episodes). Bryan focuses on overstriding and how increasing the stride rate can reduce overstriding and therefore running injuries. The importance of making gradual changes in all aspects. Different kinds of running injuries when land on the forefoot vs the heel. He thinks the type of shoes (minimalist vs cushioned etc) doesn’t make mu...
2024-07-021h 11Inside Exercise#85 - Effect of training load and shoes on running-related injuries with Dr Rasmus Østergaard Nielsen
Dr Glenn McConell chats with Associate Professor Rasmus Østergaard Nielsen from Aarhus University who is an expert on the affect of training load and shoes on running-related injuries. This is the second of a series of podcast episodes on running injuries (See Prof Irene Davis’s episode).
Rasmus went from an overweight gamer to an injured runner to a exercise researcher! His research focuses on injury prevention, especially the importance of training load. Need to make slow changes. Seems don’t need motion control shoes for those with “excess pronation”. His main point is that one needs to give t...
2024-05-271h 47Inside Exercise#84 - Effect of shoes and gait on running injuries with Professor Irene DavisDr Glenn McConell chats with Professor Irene Davis from the University of South Florida who is a top running injuries researcher and the current president of the American College of Sports Medicine. She makes the argument that we were born to run and have evolved to land on the ball of the foot during running and this reduces impact load compared with landing on the heel. Modern running shoes tend to increase the likelihood of landing on one’s heel. She is a fan of minimalist shoes, which tend to result in landing on the forefoot not the heel. Sh...
2024-04-172h 04Inside Exercise#83 - Applying Sport Science: Lessons from the Olympics and the NBA with Dr David MartinDr Glenn McConell chats with Dr David Martin. David has a remarkable and varied background starting off as a research scientist at the Australian Institute Sport and then National Sports Science Coordinator at Cycling Australia. He then became Director, Performance Research and Development at the Philadelphia 76ers. He is currently Chief Scientist, Director of Performance at Apeiron Life, San Francisco where he works to improve the healthspan of high net worth individuals. He is also an Adjunct Professor at the Australian Catholic University. We talked about all of this with a focus on the importance of belief systems in...
2024-03-302h 05Inside Exercise#82 - Heart transplant Ironmen!: Upper limits of performance post heart transplant. Prof Mark Haykowsky, Dwight Kroening and Elmar SprinkDr Glenn McConell chats with Professor Mark Haykowsky from the University of Alberta, Canada and remarkable heart transplant recipients Dwight Kroening, Edmonton, Alberta, Canada and Elmar Sprink, Cologne, Germany. Dwight was very fit before a heart defect resulted in his heart transplantation (HT) way back in 1986. Elmar was an endurance athlete who suffered a series of cardiac arrests before his HT 12 years ago. They have undertaken Ironman triathlons and more. Both had VO2 maxes in the high 50s! (ml/kg/min). They embody the importance of exercise. Really motivating stuff, incredible. I loved this chat with these three remarkable...
2024-03-132h 10Inside Exercise#81 - Muscle recovery after joint injury with Dr Chris FryDr Glenn McConell chats with Associate Professor Chris Fry from the University of Kentucky, USA. Joint injury causes muscle weakness and atrophy (reductions in muscle size) due to the the inactivity but also separately due to the injury itself. Substances are released from muscle to help repair the joint/bone. Prehab is important before surgery. There can be residual effects long after joint injury. We also discussed hypertrophy and aging and the importance of having a lot of muscle capillaries as age to obtain the optimum response to resistance training. Lots more. We had a really great chat. Chris...
2024-02-291h 19Inside Exercise#80 - Epigenetics of exercise adaptation and "muscle memory" with Dr Kevin MurachDr Glenn McConell chats with Assistant Professor Kevin Murach who is a rising star from the University of Arkansas, USA. Kevin is an expert on muscle, muscle growth, adaptation to exercise training, “muscle memory”, the regulation of muscle growth and muscle memory and the effect of aging etc. Muscle memory definitely seems real (especially in slow muscle fibers). Looks like epigenetics involved more than changes to muscle fibers nuclei. But more work needs to be done, especially in humans. We had a really great chat. I enjoyed it a lot. A very smart chap. Twitter: @KevinMurachPhD0:00. Introduction and welc...
2024-02-141h 41Inside Exercise#78 - Food, exercise and glucose "spikes": should everyone wear a CGM? Glucose spikes are normal physiology!! With Dr Guess and Prof LittleDr Glenn McConell chats with Dr Nicola Guess from Oxford University, England and Professor Jonathan Little from the University of British Columbia, Canada. Nicola is a dietitian researcher with many years of expertise including the importance or otherwise of glucose “spikes” or excursions and the pros and cons of continuous glucose monitor use. Jonathan is an expert on exercise metabolism who is coming onto the podcast for the second time after speaking previously about keto diets and exercise. A major point is the difference between having chronically elevated blood glucose levels such as in diabetes (pathology) versus having normal incr...
2024-02-021h 27Inside Exercise#79 - Exercise and the brain with Dr Jill BarnesDr Glenn McConell chats with Associate Professor from the University of Wisconsin-Madison, USA. Jill is an expert on the brain and exercise. We discussed the effect of acute (one bout) and chronic physical activity/ exercise on cognitive function, brain blood flow (BBF), dementia/Alzheimer’s disease risk and progression etc. A very interesting chat. Twitter: @Barnes_Lab0:00. Introduction and welcome2:01. How Jill got into exercise research4:25. Studying with Hiro O. Tanaka6:00. Researching with Michael Joyner7:45. How measure brain blood flow (BBF)10:00. Blood vessels that supply the brain and blood flow19:16. What would lo...
2024-01-161h 40Inside Exercise#77 - Exercise and pregnancy with Professor Margie DavenportDr Glenn McConell chats with Professor Margie Davenport from the University of Alberta, Canada. She is an expert on exercise and pregnancy. We discussed the effect of pregnancy on the health (including pre-eclampsia and gestational diabetes) and exercise performance of the mother and on the health of the fetus during pregnancy and the offspring after pregnancy. It became very clear that there needs to be more focus on the beneficial effects of exercise before and during pregnancy on both the mother and the fetus/offspring. A very interesting chat. Twitter: @ExercisePreg0:00. Introduction2:09. How Margie went from top...
2023-12-181h 45Inside Exercise#76 - Creatine in exercise and health with Professor Darren CandowDr Glenn McConell chats with Professor Darren Candow from the University of Regina. Saskatchewan, Canada. He is an expert on creatine (Cr) and the effects of creatine supplementation on resistance exercise and other exercise. He is also examining the role of creatine in bone metabolism and cognitive function.Get greater increases in strength than muscle mass when supplement with Cr during resistance training. Vegetarians/vegans have lower muscle but not lower brain Cr. Need to exercise to get benefits of Cr on muscle. Lots more. A very interesting chat. Twitter: @darrencandow0:00. Introduction1:40. How Darren got into...
2023-12-111h 54Inside Exercise#75 - Physiology of exercise in extreme environments: sex as a biological variable with Dr Nisha CharkoudianDr Glenn McConell chats with Associate Professor Nisha Charkoudian from the US Army Research Institute of Environmental Medicine, Natick, Massachusetts, USA. She is an expert on the effects of extreme environments on exercise capacity. We talked about dehydration, electrolytes, effects of humid vs dry environments etc. We also discussed the importance of considering sex as a biological variable. This included including both sexes in studies even if underpowered to examine both. We then discussed the importance of conducting more studies on thermoregulation and blood pressure with aging. A very interesting chat.0:00. Introduction3:45. What is the definition of...
2023-12-031h 00Inside Exercise#74- Are beta2-agonists just asthma treatments or also performance enhancers? With Dr Morten HostrupDr Glenn McConell chats with Associate Professor from the University of Copenhagen, Denmark. He is an expert on the effect of beta2-agonist asthma bronchodilator medications (like Ventolin) on muscle and exercise performance. We talked about what is asthma/exercise induced bronchoconstriction, can you train your lungs?, the increased prevalence of asthma in endurance athletes, can asthma limit aerobic capacity, what are beta2-agonists?, acute and chronic effects of beta2-agonists on muscle mass, sprinting, strength and endurance, side effects of beta2-agonists and negative effects of beta2 agonists on endurance exercise. Beta2-agonists should only be used for...
2023-11-261h 59Inside Exercise#73 - Protein and muscle adaptations to loading and unloading with Professor Luc van Loon
Dr Glenn McConell chats with Professor Luc van Loon from Maastricht University, The Netherlands. He is an expert with a wealth of knowledge on the role of physical activity/exercise and nutrition on muscle adaptation. A lot of his research focuses on protein and protein synthesis. He applies these studies to young healthy individuals, the aged and also has conducted important experiments on people in ICU. He makes it clear that most people, especially athletes, get enough protein in their diet so do not need to take supplements. Are there really non responders to exercise training? Anabolic resistance with...
2023-11-191h 52Inside Exercise#72 - Tendons: from exercise adaptation to injury and rehabilitation, with Professor Michael KjærDr Glenn McConell chats with Professor Michael Kjær from the Department of Clinical Medicine, Bispebjerg Hospital, the University of Copenhagen, Denmark. He is an expert on tendons and exercise. We chatted about muscle vs musculotendinous junction vs tendon, what structures get injured and why, tendon injuries: mechanisms, prevention, treatment, acute vs chronic/overuse tendon injuries, best to rest or exercise injured tendons?, whether diet, supplements or medicine can assist recovery from tendon injuries etc. We also discussed his earlier work on glucose metabolism during exercise. A very interesting chat.0:00. Introduction2:05. How Michael got into exercise research
2023-11-121h 33Inside Exercise#71 - Aging, inactivity, atrophy and exercise with Professor Sue BodineDr Glenn McConell chats with Professor Sue Bodine from the Oklahoma Medical ResearchFoundation, Oklahoma, USA. She is an expert on muscle, in particular muscle atrophy with inactivity/aging. We chatted about how with age muscle size is reduced and this is associated with a reduction in muscle fiber size and also a loss of fast muscle fibers. Resistance training (and perhaps intense endurance exercise) can attenuate the rate of muscle atrophy. We discussed how much muscle atrophy is due to age per se and how much is due to inactivity. Anabolic resistance, protein synthesis, the importance of...
2023-11-051h 22Inside Exercise#70 - Sleep, recovery and fatigue in athletes with Professor Shona HalsonDr Glenn McConell chats with Professor Shona Halson from the Australian Catholic University, Melbourne, Australia. We chatted about how much sleep athletes need compared with how much sleep they actually get. Night sleep vs naps vs total sleep in athletes vs non athletes. The importance of consistency of sleep. Caffeine, sleep and exercise performance. Is overtraining actually a lot less common than believed? Ice baths may reduce hypertrophy with resistance training but improve team sports/endurance. Effects of compression garments on recovery. The effects of mental fatigue on exercise performance. A very interesting chat. Twitter: @ShonaHalson0:00. Introduction + how...
2023-10-291h 24Inside Exercise#69 - Should middle-aged men pull on lycra? With Dr Andre La GercheDr Glenn McConell chats with Assoc Prof Andre La Gerche a world leading Sports Cardiologist from St Vincent’s Institute of Medical Research, Melbourne, Australia. Acute exercise for long periods at a high intensity can result in abnormal right ventricle function. In addition, years of long, hard exercise training is associated with increased coronary artery calcium (CAC) levels and atrial fibrillation (AF). Despite this, Andre is a huge advocate of exercise across the population and generally even in these individuals. The evidence is that exercise training increase healthspan and reduces mortality rates despite some of these changes. A very im...
2023-10-221h 52Inside Exercise#68 - Muscle fiber types revisited with Professor Wim DeraveDr Glenn McConell chats with Professor Wim Derave from the Ghent University in Belgium. We talked about the different muscle fibres/fiber types in humans and his recent evidence that pure Type 2X muscle fibers may not really exist or maybe only in some sedentary individuals. He also made the point that muscle fiber type info is not used enough in sports contexts. He outlined some non invasive ways of estimating your muscle fibre types. Finally we discussed remarkable and important findings that antihistamines may reduce some exercise training adaptations. A very interesting, long chat. Twitter: @TeamDerave.0:00. Introduction...
2023-10-152h 01Inside Exercise#67 - Limitations to VO2 max with Professor Jose CalbetDr Glenn McConell chats with Professor José Calbet from the University of Las Palmas de Gran, Canary Islands, Spain. José has a very strong research record and is a global leader in his field. He has done amazing invasive exercise studies in humans to determine the limiting factor(s) to VO2 max. We talked about what is VO2 max, the factors determining VO2 max, the limits to VO2 max, the effects of VO2 max on exercise performance, pseudoanemia, VO2 max in females, VO2 max in masters athletes etc. In general he is finding the oxygen delivery is the main li...
2023-10-071h 54Inside Exercise#66 - Exercise and the cardiovascular system with Professor Ylva HellstenDr Glenn McConell chats with Professor Ylva Hellsten from the University of Copenhagen in Denmark. She is an authority on the effect of exercise on blood flow and cardiovascular function. We talked about heart rate before exercise and blood flow and blood pressure during and after exercise. She pointed out that muscle blood flow can increase by 100-fold during exercise! We discussed the effect of physical activity and aging/inactivity and menopause on the cardiovascular system. Also the protective effects of exercise training and the importance of doing the physical activity that you enjoy. A very interesting chat. Twitter...
2023-10-011h 38Inside Exercise#65 - Interactions between exercise and insulin with Professor Erik RichterDr Glenn McConell chats with his great collaborator Professor Erik Richter from the University of Copenhagen in Denmark. Erik is an absolute authority and the godfather of the field of glucose metabolism during exercise and how exercise increases insulin sensitivity in muscle. He was the first to show that contraction can increase muscle glucose uptake without insulin but at the same time exercise increases insulin sensitivity. Very relevant for all including people with diabetes. We talked about how exercise increases glucose uptake during exercise and how it increases insulin sensitivity after exercise. Limitations of determining insulin sensitivity using the “go...
2023-09-231h 24Inside Exercise#64 - Blood flow restriction and exercise with Dr Jeremy LoennekeDr Glenn McConell chats with Associate Professor Jeremy Loenneke from the University of Mississippi, USA. He is an expert on resistance training and in particular the effect of blood flow restriction (BFR) on muscle hypertrophy and strength. He is finding that you can get similar increases in hypertrophy, and close to similar increases in strength, by conducting low load resistance training with blood flow restriction compared with high load resistance training. Surprisingly, he is also finding that there can be dissociations between increases in strength and increases in hypertrophy when undertake resistance training. We also discussed other interesting research...
2023-09-171h 54Inside Exercise#63 - Adipose tissue adaptations to exercise and exercise and antipsychotics with Dr David WrightDr Glenn McConell chats with Professor David Wright from the University of British Columbia, Canada. He has undertaken a lot of important work on the effect of exercise on muscle glucose uptake and mitochondria and then has branched out to examine the effect of exercise training on mitochondria in adipose tissue (fat). We discussed his work around that and then talked about an interesting new focus of his work around the metabolic effects of antipsychotics. He is finding that exercise can prevent the acute blood glucose raising effects of antipsychotics. A very interesting chat.0:00. Introduction and how David...
2023-09-101h 19Inside Exercise#62 - Interaction of exercise with muscle circadian clocks with Dr Karyn EsserDr Glenn McConell chats with Professor Karyn Esser from the University of Florida, USA. She is an authority on circadian biology. We discuss whether exercise affects muscle circadian clocks and whether muscle clocks affect exercise. What is the best time to exercise and to eat etc. Also the effects of jet lag and shift work and how to best manage these. A very interesting chat. Karyn’s Twitter: @kaesser.0:00. Introduction2:30. How Karyn got into exercise research.4:40. She was “picked up” by Arnold Schwarzenegger5:32. Her muscle hypertrophy work7:00. What are circadian rhythms?9:40. Jet lag11...
2023-09-041h 20Inside Exercise#61 - Volume versus intensity with Dr David BishopDr Glenn McConell chats with Professor David Bishop from Victoria University in Melbourne, Australia. He has a broad background in exercise physiology research and has focused for many years on exercise and muscle mitochondria. He finds that low volume, prolonged exercise tends to increase mitochondrial volume more than mitochondrial function while sprint exercise training does the opposite, increasing mitochondrial function more than mitochondrial volume. He hypothesizes that polarized type training may be best to get increases in both mitochondrial function and mitochondrial volume. A very interesting chat. David’s Twitter: @BlueSpotScience0:00. Introduction2:45. Defining the different training zones
2023-08-271h 21Inside Exercise#60 - Skeletal muscle aging and mitochondria: thinking beyond the powerhouse with Dr Russell Hepple
Dr Glenn McConell chats with Professor Russell Hepple from the University of Florida, USA. He is an expert on muscle mitochondria. We tend to think of the mitochondria as the powerhouse of the cell. As Russ clearly explains there is a lot more going on than only this. It is very important that the inner mitochondrial membrane remains impermeable. However, there are situations such as aging, ischemia reperfusion injury, muscle dystrophies and perhaps cancer/chemotherapy where calcium and reactive oxygen species can build up and affect this permeability. This mitochondrial permeability transition is a major focus of Russell’s re...
2023-08-201h 01Inside Exercise#59 - The gut microbiome in health and sport with Dr Orla O'SullivanDr Glenn McConell chats with Dr Orla O’Sullivan from the Teagasc Food Research Centre, from Ireland. She is a research expert effect of diet and exercise on the gut microbiome (the types of cells in the gut microbiome based on the DNA measurements). She has looked at the gut microbiota in rugby players, cricketers, ironman and other sports. She emphasized the importance of having a diverse gut microbiome. This is a very good episode to extend upon the episode on gut microbiota and exercise with Dr Edward Chambers (podcast episode #57). Very interesting work and a fun chat. Twitter: @Or...
2023-08-141h 20Inside Exercise#58 - Exercise in the cold: impacts on performance and health with Dr Mike Tipton
Dr Glenn McConell chats with Professor Mike Tipton from University of Portsmouth, England. He is an absolute authority on exercise in extreme environments. We talked initially about his important work examining the causes and prevention of drowning in cold water. Autonomic conflict and triathlon mass starts. We then discussed exercise in the cold and cold adaptations and cross adaptation between cold, heat, altitude etc. Smart to pre-cool and cool after exercise in the heat? Mike is very heavily involved with translating his research to the media and lifesaving organizations etc. Very interesting work and a fun chat. Twitter: @ProfMikeTipton
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2023-08-051h 31Inside Exercise#57 - Gut microbiota and exercise with Dr Edward Chambers
Dr Glenn McConell chats with Dr Edward Chambers from Imperial College London who is an expert on the gut microbiota, exercise and metabolism. He has shown that some fibre can be fermented to short chain fatty acids (SCFA) by gut microbiota which can influence skeletal muscle metabolism. In addition, these SCFA can affect appetite. He has also shown that exercise and/or carbohydrate ingestion reduces appetite. Important message, eat the recommended amount of fibre. Very interesting work and a fun chat.0:00. Introduction2:21. What is the gut microbiota and why important?4:02. 1.5-2kg of body weight is...
2023-07-301h 35Inside Exercise#56 - Muscle plasticity, aging and exercise with Dr Benjamin Miller
Dr Glenn McConell chats with Professor Benjamin Miller from the Oklahoma Medical Research Foundation (OMRF) who is an expert on muscle proteostasis /plasticity in response to exercise and aging. He has evidence that muscle atrophy with aging may be due more to increased protein breakdown than reduced protein synthesis. He also has found that the top diabetes drug metformin can impair some of the benefits of exercise.0:00. Introduction and Benjamin’s current employment etc6:09. Benjamin’s early background in exercise and science8:05. Healthspan vs lifespan. Can extend lifespan?13:12. Metformin can impair some of the benefits of e...
2023-07-231h 17Inside Exercise#55 - Reactive oxygen species (ROS) and exercise with Dr Carlos Henríquez-OlguínDr Glenn McConell chats with Dr Carlos Henríquez-Olguín from The University of Copenhagen, Denmark. Carlos is an up and coming rising star exercise metabolism researcher. He discusses the challenges of doing mechanistic exercise research in Chile and how he ended up moving to the University of Copenhagen. Language challenges etc. He has been doing really ground breaking research on reactive oxygen species (ROS) and contraction/exercise and already won awards for his research. Twitter: @MuscleBiology.0:00. Introduction/reason invited Carlos onto Inside exercise4:00. Challenges doing mechanistic exercise research in Chile etc9:37. Cell culture and mouse RO...
2023-07-171h 29Inside Exercise#54 - Exercise and immunity with Dr Michael Gleeson
Dr Glenn McConell chats with Emeritus Professor Michael Gleeson from Loughborough University, England. He is the biggest global name with many decades of research examining the effects of exercise and diet on the immune system. Exercise is beneficial for the immune system unless it is undertaken at a very high /elite level. A very interesting chat. Twitter: @profmikegleeson0:00. Introduction/Michael’s early career exercise research training5:41. Early studies on exercise and immune system: Eric Newsholme6:57. Prolonged exercise reduces plasma glutamine (leukocytes)8:30. Michael retired in 2016 but still writing books etc9:56. Increased upper respiratory tract infections af...
2023-07-101h 30Inside Exercise#53 - Aging, exercise and muscle mitochondrial energetics with Dr Paul Coen
Dr Glenn McConell chats with Dr Paul Cohen from Translational Research Institute for Metabolism and Diabetes, AdventHealth Orlando, Florida, USA. He has a very strong track record of research examining muscle mitochondria in health and disease and in particular the effects of exercise in attenuating the reductions in mitochondrial function with age. A very interesting chat. Twitter: @CoenPM
0:00. Introduction/Paul’s exercise research training
3:10. Exercise, aging and inflammation markers etc
5:55. Bret Goodpaster/Advent Health
8:53. Muscle mitochondria functions
10:15. Mitochondria: energetics, function, biogenesis
13:11. Effects of aging on mitochondria
16:15. Mitochondria energetics, VO2 max and muscle power with age
22:30. Isolated mito vs fibers vs...
2023-07-011h 18Inside Exercise#52 - Environmental physiology: results and lessons from the lab vs real life with Dr Lars Nybo
Dr Glenn McConell chats with Professor Lars Nybo from the University of Copenhagen. He is an expert on the effects of environmental conditions on exercise. Here he discussed factors effecting cycling performance and then focused on circumstances where one needs to be careful applying findings from the lab to the real world. A very interesting chat. Twitter: @Nyborger Nybo0:00. Introduction2:20. Lars incredible hour record on the bike4:45. Lab vs real world effects of temperature on cycling9:26. Coefficient of drag/watts/watts per kg11:31. VO2 max vs short time trials13:21. VO2 max (relative vs...
2023-06-261h 38Inside Exercise#51 - Maximizing muscle hypertrophy with Dr Brad SchoenfeldDr Glenn McConell chats with Professor Brad Schoenfeld from Lehman College, The City University of New York, the Bronx, New York. He has a very strong track record on research examining how to maximize muscle hypertrophy and also important protein synthesis and strength studies. He also applies his knowledge being a former personal trainer and a successful competitive natural body builder. We discussed all aspects of resistance training for body builders and also for more recreational strength trainers.A very interesting chat. Twitter: @BradSchoenfeld0:00. Introduction/overview of Brad’s personal/sporting and research background4:04. Relative lack of...
2023-06-201h 17Inside Exercise#50 - Acute catabolic (yes, catabolic...) response of bone to exercise with Dr Wendy Kohrt
Dr Glenn McConell chats with Professor Wendy Kohrt from the University of Colorado Anschutz Medical Campus. She has an extremely strong track record of research on how exercise affects bone. She has changed her thinking of late after finding that acute exercise actually has a catabolic effect on bone even though overall, it can have beneficial effects. This is dependent on the actual exercise/sport undertaken and the duration. A very interesting chat.0:00. Introduction/overview of Wendy’s exercise and research background5:26. How Wendy got interested in bone/John Holloszy8:48. Exercise, bone loss and NSAIDs13:08. Cy...
2023-06-131h 29Inside Exercise#49 - Remarkable benefits of exercise in myopathy patients with Dr Mark Tarnopolsky
Dr Glenn McConell chats with Professor Mark Tarnopolsky from McMaster University in Canada. Mark has done pioneering studies in many areas including sex differences and exercise, HITT training and creatine supplementation. Today we focus on his remarkable work with muscle myopathies. Exercise can be beneficial in all muscle myopathies in regards to function and/or healthspan and/or lifespan. The type of exercise will differ depending on the myopathy: endurance, resistance, or both.0:00. Introduction and overview of Mark’s exercise, clinical and research4:45. McMaster University: Stu Phillips, Marty Gibala and Mark6:30. His sex differences and exercise re...
2023-06-081h 37Inside Exercise#48 - Dr David Costill: Legend of exercise physiology and human performance
Dr Glenn McConell chats with Emeritus Professor David “Doc” Costill who is an absolute legend of exercise physiology and human performance. He was Founder and Director of the Human Performance Laboratory at Ball State University in Muncie, Indiana, USA. He made the lab one of the top labs in the world and has a remarkable track record. He supervised the who’s who of exercise physiology research including 7 people (8 including me) who have been on the Inside exercise podcast.0:00. Introduction, Dave’s the reason I started this podcast3:54. Frank Pyke5:37. Many people on the podcast were supervis...
2023-05-292h 12Inside Exercise#47 - Speed-duration relationship across the animal kingdom with Dr Mark BurnleyDr Glenn McConell chats with Dr Mark Burnley from the Loughborough University in England. He is an expert on critical power (cycling) and critical speed (running). We compared and contrasted the speed duration relationship across the animal kingdom. Mark is an absolute wealth of knowledge on exercise intensity domains and critical power etc and comparative exercise physiology. Critical power is essentially one’s aerobic capacity and W’ is essentially one’s work capacity. Twitter: @DrMarkBurnley0:00. Introduction and how Mark’s entry into research6:12. Exercise intensity domains/ Critical power10:02. Single out exercise to determine critical power11:55. Marks st...
2023-05-211h 52Inside Exercise#46 - What are we polarizing in polarized endurance training? Dr Stephen SeilerDr Glenn McConell chats with Professor Stephen Seiler from the University of Agder in Norway. He is American who started his career in USA before moving to Norway almost 30 years ago. He points out that most exercise training research is based around university semesters with mainly untrained to trained transitions which is very different to what athletes do. Stephen coined the term polarized training in 2004 and makes the argument that this is the best way to train and that most world class endurance athletes train this way. This discussion is interesting to compare and contrast with recent episodes with...
2023-05-141h 55Inside Exercise#45 - From heat shock doc to kettlebells with Dr Pope Moseley
Dr Glenn McConell chats with Professor Pope Moseley from Arizona State University in the United States. Pope has a lung and critical care background. We spoke about his early heat shock protein work with Carl Gisolfi, a giant of research on exercise and the gut. Also heat, heat shock proteins, gut leak and heat stroke, exercise training and gut leak, heat shock proteins and autophagy, “Heat shock proteins are how cells think”, heat related illness is only a fraction of disease driven by heat. After a serious acute back injury requiring back surgery, Pope found Kettlebells to be very usef...
2023-05-071h 18Inside Exercise#44 - The science of sports injuries and how to prevent and treat them with Dr Kristian ThorborgDr Glenn McConell chats with Professor Kristian Thorborg from the University of Copenhagen in Denmark who also has s position at Lund University in Sweden. We spoke about the role of the placebo effect, sports injury prevention and especially the role of eccentric exercise, plyometrics, whether stretching reduces sports injuries, prehabilitation, exercise to avoid surgery, rehabilitation, is ice useful, effectiveness of adjunct treatments, start with the least aggressive approach etc. Twitter: @KThorborg
0:00. Introduction and Kristian’s background8:15. Evidence base for physiotherapy/ physiotherapy is a profession12:20. Physiotherapy treatments for injury pain14:21. The placebo effect in...
2023-04-301h 44Inside Exercise#43 - The importance of exercise in space with Dr Scott Trappe
Dr Glenn McConell chats with Professor Scott Trappe, Director of the Human performance laboratory at Ball State University, Indiana, USA. We spoke about the influence that Scott’s supervisor, the great David “Doc” Costill, has had on exercise physiology (long time Ball State HPL Director before Scott). We then discussed the negative effects of space on the human body and whether exercise can minimize these negative effects. In space slow muscle fibers atrophy more than fast fibers and there is a large shift to fast fiber types. Exercise attenuates this. A very interesting, relaxed, fun chat. @HPLBallState
0:00. Introduction etc3:2...
2023-04-241h 41Inside Exercise#42 - Circadian rhythms, exercise and type 2 diabetes with Dr Juleen Zierath
Dr Glenn McConell chats with Professor Juleen Zierath who has had a remarkable background with current senior roles at both the Karolinska Institute in Sweden and the University of Copenhagen in Denmark. She was also previously the Chair of the Nobel Committee. We discuss the effects of circadian rhythms on: muscle insulin sensitivity, metabolic responses to exercise in T2D vs controls, exercise performance, metabolism in men vs women and integrative physiology. A very interesting chat. Twitter: @JuleenRZierath.
0:00. Introduction and Juleen’s academic and research background
7:39. Ball State University and David “Doc” Costill
9:40. What it’s like on the Nobel Pr...
2023-04-1756 minInside Exercise#41 - Zone 2 training: why all the talk? With Dr Andrew CogganDr Glenn McConell chats for a second time with Associate Professor Andrew Coggan from Indiana University, Purdue University, Indianapolis (IUPUI), USA. Andy was an elite time trial cyclist who has a very impressive research track record. He also wrote the first book on training and racing using power (training levels). As was the case last week with Michael Joyner, Andy makes the case that different types of training can result in similar results (and there’s nothing special about zone 2). “Nothing magic about training at a particular intensity”. Andy was the first guest on Inside exercise in June 2022 talking about...
2023-04-091h 28Inside Exercise#40 - The history of endurance training methods with Dr Michael JoynerDr Glenn McConell chats for a second time with Professor Michael Joyner from the Mayo Clinic, Minnesota, USA. Michael blew me away with his absolutely amazing knowledge on past athletes and coaches and their endurance training methods. Very different types of training can result in similar results. His running Haiku: Run a lot of miles, some faster than your race pace, rest once in a while. Michael was first on the podcast on October 9th, 2022. Michael’s Twitter: @DrMJoyner
0:00. Introduction2:25. Foot races in the 1700s and 1800s (running 5 min/mile!)3:56. Pheidippides: run from Marathon to At...
2023-04-0254 minInside Exercise#39 - Why muscle glycogen is important with Dr Niels Ørtenblad
Dr Glenn McConell chats with Professor Niels Ørtenblad from the University of Southern Denmark. He is an expert on muscle glycogen. We discussed the history of muscle glycogen and exercise research, the effect of diet and exercise training on muscle glycogen levels and use, the distribution and use of muscle glycogen within different muscle fibre compartments, unusual to fully deplete muscle glycogen during exerciseand the potential role of muscle glycogen depletion in muscle fatigue. Very interesting stuff. Niel’s Twitter: @nortenblad.0:00. Introduction and Niels background6:15. History of the study of muscle glycogen and exercise9:15. Mus...
2023-03-251h 13Inside Exercise#39 - Do keto diets and ketone supplements make sense for exercise and health with Dr Jonathan LittleDr Glenn McConell chats with Professor Jonathan Little from University of British Columbia. Kelowna, Canada. He is an expert on metabolism, nutrition, type two diabetes and exercise. We discussed what are keto (ketogenic) diets, different types of keto diets, the rationale for them and their effect on heath and exercise performance. We then did the same with ketone supplements. Whether there is a rationale for keto diets depends on who you are (overweight vs lean, insulin sensitive vs T2D, athletes vs non athlete etc).
0:00. Introduction and overview of the area
3:38. Jonathan’s academic and sporting ba...
2023-03-181h 23Inside Exercise#38 - Harassment, abuse and mental health in athletes with Dr Margo MountjoyDr Glenn McConell chats with Professor Margo Mountjoy from McMaster University in Canada. A wide ranging and at times emotional discussion about the types of harassment and abuse (psychological abuse underlies most), prevalence of abuse (higher in marginalized groups), power relationships, reporting policies and procedures, barriers to reporting abusive behavior, the Nasser case, how empower the good people to effect change etc. Trauma informed care, the 4Rs: Realising that trauma is common, recognizing the signs of trauma in other people, responding to it and resisting retraumatization. A very passionate, compassionate and caring person.
0:00. Introduction and Margo’s sp...
2023-03-111h 04Inside Exercise#37 - Exercise in the heat, dehydration, fluid ingestion and circulation with Dr José González-AlonsoDr Glenn McConell chats with Professor José González-Alonso from Brunel Univesity London. We discussed exercise in the heat, dehydration, fluid ingestion, blood flow, metabolism and human circulation. He has a very strong research track record having researched these areas for around 35 years. We discuss how he began his career doing research with some very big names.
0:00. Introduction and how José got into research etc
6:20. Does heat stress reduce muscle blood flow during exercise?
8:20. Exercise in mild environmental conditions
11:20. Loss of bodily fluids during exercise
14:13. Heart rate and the perip...
2023-03-031h 24Inside Exercise#36 - Effect of the menstrual cycle, oral contraception, pregnancy and the menopause on exercise performance with Dr Kirsty Elliott SaleDr Glenn McConell chats with Professor Kirsty Elliott-Sale from Manchester Metropolitan University, England. She is an expert on female exercise physiology . We discuss the effects of the menstrual cycle, oral contraception, pregnancy and the menopause on exercise performance. As will become apparent, more research needs to be done on these important areas.
0:00. Introduction and Kirsty’s intro to research etc
5:05. Finally more research on female exercise physiology
6:25. Men have been the default research participants
9:53. Sex difference studies are a very different issue
11:47. Effects of the menstrual cycle on exercise performance
-Systematic review/me...
2023-02-241h 11Inside Exercise#35 - Gaining muscle to combat losing muscle with Dr Stuart PhillipsDr Glenn McConell chats with Professor Stuart Phillips from McMaster University in Canada. He is the world expert on protein needs for optimal muscle mass with exercise. We discussed gaining muscle to combat losing muscle. The discussion centered around resistance training, dietary protein needs, whether need protein from meat, the timing of protein intake, the need for protein supplements and protein needs with aging. Lots more. He has been very open to changing his views based on the data. An important, fun chat.
0:00. Introduction and Stuart’s research journey
7:50. Gaining muscle to combat losing muscle
10:35. Mu...
2023-02-171h 31Inside Exercise#34 - The psychobiology of endurance performance with Dr Samuele MarcoraDr Glenn McConell chats with Professor Samuele Marcora from the University of Bologna in Italy. He is an expert on the psychobiology of endurance performance and fatigue. We discussed the importance of the perception of effort/rating of perceived exertion on exercise performance and fatigue. Pros and cons of zoning in vs zoning out. How the perception of effort can be modified by factors such as exercise training, mental fatigue and caffeine.
0:00. Introduction and Samuele’s research journey
8:33. Feeling of fatigue when at rest vs fatigue during exercise
11:03. “Central fatigue”
12:09. Fatigue and perception of effort
15:33. Doesn’t agree with the Central gover...
2023-02-111h 45Inside Exercise#33 - Fat metabolism, insulin resistance and exercise with Dr Graham HollowayDr Glenn McConell chats with Professor Graham Holloway from the University of Guelph in Canada. He is an expert on mitochondrial bioenergetics. We discussed the effect of exercise intensity and duration and exercise training on fat/lipid and carbohydrate metabolism, whether alterations in substrate availability such as high fat diets, high fat meals, high carbohydrate meals etc affect fat oxidation and mitochondrial function and the effect of high fat diets on insulin sensitivity. Central role of ADP.
0:00. Introduction and Graham’s sporting and research journey
6:06. Fat availability and fat oxidation at rest snd during exercise
8:40. Ca...
2023-02-051h 16Inside Exercise#32 - Carbohydrate metabolism during exercise with Dr Mark HargreavesDr Glenn McConell chats with Professor Mark Hargreaves from the University of Melbourne in Australia. He is a leader in exercise metabolism/physiology and was Glenn’s PhD supervisor. The discussion centred around the effects of muscle glycogen availability and carbohydrate (CHO) ingestion on exercise metabolism and also performance/fatigue. There was also discussion of high fat/ketogenic diets, GLUT-4, the central nervous system and the effect of the volume of fluid ingested with and without addition of electrolytes.
0:00. Introduction and Mark’s beginnings in exercise research
9:10. Effect of exercise intensity on the fuel mix used
1...
2023-01-291h 14Inside ExerciseInactivity- the imperceived muscle stressor with Dr Paul GreenhaffDr Glenn McConell chats with Professor Paul Greenhaff from the University of Nottingham in England. He has been a leader in exercise metabolism research for over 30 years. He was the top global researcher in creatine and exercise for many years. His focus over several years has been on inactivity. We discuss the metabolic effects of inactivity and immobilization on insulin sensitivity and protein synthesis.
0:00. Introduction and Paul’s academic journey
4:00. What is physical inactivity and how is it measured?
8:53. Inactivity itself has negative effects that are under appreciated
10:56. Rodent models of activity/inactivity
13:25. Be...
2023-01-221h 10Inside ExerciseAltitude training and hypoxic conditioning with Dr Grégoire MilletDr Glenn McConell chats with Professor Grégoire Millet from the University of Lausanne in Switzerland. He is an absolute world leader in research into altitude training and hypoxic conditioning. This area has progressed greatly from Live High-Train High (LHTH) to Live High-Train Low (LHTL),
LLTH and LHTL (and High). The type of attitude training/hypoxic conditioning one would undertake depends on if training for endurance or team sports. We also discussed using low oxygen (hypoxia) and high oxygen (hyperoxia) for health benefits.
0:00. Introduction and Grégoire’s background
4:58. History of altitude training
6:52. Many comb...
2023-01-151h 25Inside ExerciseExercise protects and treats fatty liver with Dr John ThyfaultDr Glenn McConell chats with Professor John Thyfault from the University of Kansas Medical Center. We discuss how when one takes in more calories than they expend, this results in elevated fat and glucose in the blood which disrupts liver metabolism. This can result in fatty liver and insulin resistance. Exercise can prevent and treat fatty liver even independently of body weight. There are important sex differences too. We also touch on ketones, carbohydrates, insulin and the liver.
0:00. Introduction and how got into exercise/liver research
6:48. Liver metabolism during exercise
8:17. Liver and insulin resistance
10:55...
2023-01-081h 09Inside ExerciseHow does exercise affect metabolism after eating with Dr Javier GonzalezDr Glenn McConell chats with Professor Javier Gonzalez from the University of Bath. We discuss carbohydrate (CHO) metabolism at rest when fasted vs fed, during exercise when fasted vs fed and the effects of exercise on metabolism after a meal. We also discuss muscle and liver glycogen resynthesis and the effects of different types and amounts of carbohydrate. Finally, we touch on Javier’s study with ketone supplementation and EPO.
0:00. Introduction
2:23. How got into exercise research
4:43. Metabolism at rest when fasted and in response to a meal
7:30. Effect of exercise on metabolism after a me...
2023-01-011h 12Inside ExerciseUnravelling the mysteries of the vasculature in muscle with Dr Katrien de BockDr Glenn McConell chats with Professor Katrien de Bock from ETH Zürich - Swiss Federal Institute of Technology. We discussed how exercise training increases blood vessels in skeletal muscle. Also muscle cells and blood vessels in regards to injury/repair and cancer. We also discussed exercise and leucine sensitivity.
0:00. Introduction
2:00. What is the vasculature. Blood vessels Endothelial cells etc
5:46. Redirecting blood to the muscle during exercise
7:16. Exercise training increases blood vessels in muscle
8:50. Exercise also improves blood vessel function
10:13. How does exercise increase muscle blood vessels? Called...
2022-12-2554 minInside ExerciseHerman's theory that exercise doesn't affect body weight with Dr Herman PontzerDr Glenn McConell chats with Professor Herman Pontzer who is a Human Evolutionary anthropologist from Duke University. Herman has undertaken research with current day hunter gather communities and shown that although they are a lot more physically active than western societies, their average energy expenditures are not higher!! Constrained energy model (energy compensation): that when exercise the body constrains other energy use so less change in energy expenditure than would expect. Based on this he has the theory that exercise doesn’t affect energy expenditure/body weight. Glenn challenged these ideas and was a devils advocate throughout this discussion....
2022-12-071h 12Inside ExerciseYour parent's diet and exercise affects your health with Dr Laurie GoodyearDr Glenn McConell chats with Professor Laurie Goodyear from the Joslin Diabetes Centre at Harvard Medical School. Laurie is a very big name in the field of exercise metabolism with a remarkable track record. She has examined glucose and fat metabolism during exercise and more recently has been focusing on developmental origins of health and disease and the benefits of exercise. Exercise of the mother, the father and even the grandmother has beneficial effects on offspring, especially if the parents were on a high fat diet. The role of epigenetics is discussed.
0:00. Introduction
3:20. How Laurie en...
2022-11-181h 04Inside ExerciseMuscle fatigue with Dr Håkan WesterbladDr Glenn McConell chats with Professor Håkan Westerblad from the Karolinska Insitute in Sweden. Håkan is a massive name in the field examining the mechanisms of muscle fatigue. The first 20 min is a general discussion of fatigue during exercise which is suitable for a general audience. Then it becomes more complex as as we discuss the mechanisms causing fatigue.
0:00. Introduction
0:56. His background, semi-retired, Scandinavian research
5:36. Definition of fatigue
7:39. Potential sites of fatigue. Central vs peripheral fatigue.
10:34. Fatigue during exercise in the heat.
14:02. Eccentric/concentric contractions and forc...
2022-11-121h 34Inside ExerciseMuscle injury, repair and aging with Dr Abigail MackeyDr Glenn McConell chats with Associate Professor Abigail Mackey from the University of Copenhagen. Abigail is an expert on muscle injury, repair and aging. They discussed these plus the protective effect of repeated bouts of eccentric exercise, whether it’s smart to take anti-inflammatories after injury, different types and areas of injuries, causes of injuries, treatment of muscle injuries, muscle innervation, exercise and age and more.
0:00. Introduction and how got into the area
4:32. Composition of skeletal muscle. Muscle biopsies, mixed muscle, single muscle fibers etc.
8:31. Muscles response to injury. Satellite cells.
12:12. Muscle...
2022-11-041h 08Inside ExerciseExercise and insulin action with Dr Jorgen WojtaszewskiDr Glenn McConell chats with Professor Jorgen Wojtaszewski from the University of Copenhagen. Jorgen has an exceptional track record of research examining how exercise increases glucose uptake during the exercise and how exercise increases the sensitivity of muscle to insulin. We discuss insulin resistance, insulin sensitivity, type 1 diabetes and exercise, type 2 diabetes and exercise, glucose uptake during exercise, glucose uptake after exercise, best exercise to increase insulin action, gender effects, aging effects etc. Also the likelihood of developing a drug to mimic exercise’s effect of insulin sensitivity.
0:00. Introduction and how he got into the area
2...
2022-10-281h 00Inside ExerciseRelative energy deficiency in sport (RED-S) with Dr Trent StellingwerffDr Glenn McConell chats with Dr Trent Stellingwerff from the Canadian Sport Institute Pacific. Trent has a very interesting background in applied research and translation through coaching Olympic athletes etc. Formerly head of R&D at PowerBar. In a really fun chat we talked mainly about his research with the very important relatively new area of relative energy deficiency in sport (RED-S). RED-S effects not only exercise performance but also health. We also sports performance after pregnancy. Important take home: Need to be in long-term energy balance for long term ideal body composition, health and exercise performance. Twitter: @TStellingwerff.
2022-10-211h 13Inside ExerciseThe skeptics guide to sports science with Dr Nick TillerDr Glenn McConell chats with Dr Nick Tiller from Harbor UCLA. Nick is a COPD and exercise researcher with other interests such as ultramarathon. However, the focus of this episode is on his expertise in regards to the importance of being skeptical of health and fitness claims. He has written the book A skeptics guide to sports science. He makes some very important points re critical thinking, confirmation bias, logical fallacies, appeals to nature, false dichotomy, the role of social media, pre-bunking. A very articulate and interesting person. Twitter: @NBTiller
0:00. Introduction
3:05. Sits in Karlman Wasserman ol...
2022-10-151h 13Inside ExerciseIntegrative physiology of exercise with Dr Michael JoynerDr Glenn McConell chats with Professor Michael Joyner from the Mayo Clinic. He has a remarkable background being an anaesthesiologist with wealth of research experience and knowledge in exercise physiology. More recently he has published around 20 high impact papers on the use of convalescent plasma in Covid19! An example of how he is so open to new ideas. A very interesting chat. Twitter: @DrMJoyner.
0:00. Introduction
1:45. Eliud Kipchoge’s recent marathon world record
3:27. Michael’s athletic background
4:32. Determinants of endurance performance. Including more discussion of Kipchoge.
8:09. Greatest athletes historically. Remarkable knowledge...
2022-10-0855 min
Sigma Nutrition Radio#456: Prof. Glenn McConell – Glucose Uptake During Exercise & Muscle Insulin SensitivityExercise improves metabolic control both via increasing muscle glucose uptake during muscle contractions by insulin-independent mechanisms and by increasing skeletal muscle insulin sensitivity after physical activity. A reduction in skeletal muscle insulin sensitivity is an early event in the development of not only prediabetes, metabolic syndrome, and type 2 diabetes but is also associated with other conditions such as cardiovascular disease and some cancers. One of the researchers that has been at the forefront of research in this area for many years is Professor Glenn McConell. In this episode we discuss glucose uptake during and after exercise, looking...
2022-10-041h 03Inside ExerciseHelping to start and maintain physical activity with Dr Stuart BiddleDr Glenn McConell chats with Professor Stuart Biddle who has a dual affiliation with the University of Southern Queensland (Australia) and the University of Jyvaskyla (Finland). A very interesting and informative chat with lots to think about. Stuart feels that we need to focus more on the environment than we have done, as well as the individual (particularly affect/feeling states/enjoyment), to get increased physical activity. Not a fan of the "Extraordinary claims" around HIIT.
0:00. Introduction and Stuarts position
3:15. Behaviors, determinates/drivers of physical activity
5:45. It’s complex 6:50. Psychological perspective: individual vs environme...
2022-10-0159 minInside ExerciseHeat therapy, exercise and chronic disease with Dr Paige GeigerDr Glenn McConell chats with Professor Paige Geiger from the University of Kansas Medical Centre on Heat therapy, exercise and chronic disease. Paige has undertaken very important mechanistic and allied work in this field. We discussed many things (see time stamps below).
0:00. Introduction how got into the area
6:26. How first idea to look at heat and diabetes Phil Hooper in 1999 put people with T2D in hot tubs
9:00. Heat shock proteins (HSPs) Activated by many stresses in addition to heat. Many roles.
10:53. High fat diets and heat Need to raise body temp...
2022-09-231h 06Inside ExerciseExercise and type 2 diabetes with Dr John HawleyDr Glenn McConell chats with Professor John Hawley from the Australian Catholic University on Exercise and type 2 diabetes. John is one of the most recognized names in exercise metabolism. He has published over 300 journal articles (Google scholar: 40,000 citations, H index 113). We discussed many things (see time stamps below).
0:00. Introduction
1:34. Putting exercise and diet ahead of medical interventions
4:52. John’s background / the All blacks
6:14. Acute exercise in type 2 diabetes
8:28. Exercise snacking
11:16. Intensity of exercise
HIIT exercise increases glucose levels.
12:29. Don’t complicate it, just exercise
14:34. Take the stairs
17:02. Muscle gluc...
2022-09-151h 02Inside ExerciseCarbohydrate and protein requirements of endurance athletes with Dr Jørgen JensenDr Glenn McConell chats with Professor Jørgen Jensen from the Norwegian School of Sport Sciences about Carbohydrate and protein requirements of endurance athletes. He has over 30 years of experience examining these areas. We focussed on muscle glycogen depletion during exercise and glycogen resynthesis after exercise. He thinks no mechanistic link between glycogen content and fatigue. Also discussed combined carbohydrate and protein ingestion and protein requirements for endurance athletes. A short discussion on his work with caffeine and exercise and his current research.
0:00. Introduction and how Jørgen got into research
3:25. His initial glycogen metabolism rese...
2022-09-0959 minInside ExerciseGenetics and exercise in health and performance with Dr Claude BouchardDr Glenn McConell chats with Professor Claude Bouchard about Genetics and exercise in health and performance. He recently retired at 82 yrs from the Louisiana State University Pennington Biomedical Research Center. He had made an amazing contribution with an H index of 191 and 173,000 citations!! (Google scholar).
0:00. Introduction
1:06. Got Covid19 then went flying fishing!
3:38. How got into genetics research
5:40. Working out the role of genetics before could measure DNA easily
11:05. Using physiology to assist with the genomic pursuit
12:57. Complex traits are influenced by 100s to 1000s of variants
14:3...
2022-09-0256 minInside ExerciseInactivity and exercise resistance and 4 second SIT training with Dr Eddie CoyleDr Glenn McConell chats with Professor Eddie Coyle from the University of Texas at Austin. Eddie has been instrumental in our understanding of the effects of carbohydrate ingestion and fluid ingestion during prolonged exercise and also physiological characteristics of endurance athletes (amongst other areas). Here we talk about his more recent very important and novel work.
0:00 Introduction
3:08. Inactivity and exercise resistance.
If do not undertake enough steps during the day (inactive) then exercise at night you will not increase your fat oxidation the next day. Standing no better than sitting in regards to th...
2022-08-2651 minInside ExerciseWomen in science and female exercise physiology with Dr Abbie Smith-RyanDr Glenn McConell talks with Professor Abbie Smith-Ryan from the University of North Carolina Chapel Hill about Women in science and female exercise physiology. Abbie has done remarkably well to publish 165 papers and be rapidly promoted to full Professor. Abbie talks about the challenges for women in science and also her research with female exercise physiology.
0:00. Introduction and how got into research
3:30. Women in science
Women under represented in science and exercise science. Discussed challenges for women in science, more male Professors/senior roles: lack of mentors for women about how to do well...
2022-08-1954 minInside ExerciseAre the lungs built for exercise? With Dr Jerome DempseyDr Glenn McConell chats with Professor Jerry Dempsey from the University of Wisconsin Madison School of Medicine and Public Health on "Is the lung built for exercise". Jerry is a legend and the most recognizable name in the area, having examined the respiratory system and exercise for 60 years. He is 84 and although he says he retired at 82 he is still heavily involved.
0:00. Introduction
0:47. How respiratory system responds to acute exercise
4:25. Regulation of respiration
5:54. Lungs not limiting to exercise in most people.
11.26. Lungs can limit exercise in very well trained.
...
2022-08-111h 11Inside ExerciseExercise and cancer with Dr Kathryn SchmitzDr Glenn McConell chats with Professor Kathryn Schmitz from Penn State University who is a world leading cancer researcher who has been involved in many guidelines on exercise in cancer. We have all been touched by cancer in various ways and I feel confident that you will get a lot out of this.
0:00. Introduction and how got into the area
5:23. Lifestyle factors contribute to cancer risk etc
6:23. Exercise and cancer control continuum.
11:01. People close to us and cancer
15:14. History of exercise oncology
19:28. Exercise and cancer risk
22:30...
2022-08-0657 minInside ExerciseCan extreme exercise damage the heart? With Dr Benjamin LevineDr Glenn McConell chats with Professor Benjamin Levine who has the best global research track record in Sports cardiology/cardiovascular physiology and exercise. He is the founder and Director of the Institute for Exercise and Environmental Medicine at Texas Health Presbyterian Hospital Dallas, Professor of Internal Medicine/Cardiology and Distinguished Professor of Exercise Sciences at the University of Texas Southwestern Medical Center. He has published over 400 journal articles with a very high H-index of 109.
We enjoyed a broad ranging discussion including:
- how the main determinant to be an endurance athlete/ to have a high VO2...
2022-07-311h 10Inside ExerciseSports nutrition for optimal sports performance with Dr Louise BurkeDr Glenn McConell chats with Professor Louise Burke from Australian Catholic University. Louise is an extremely experienced academic dietician and practitioner with probably the best current track record in the area. In a wide ranging discussion we discussed many things including how she got into the field ("by accident"), the importance of high CHO intake compared with high fat/ketogenic diets for endurance performance, how forcing the body to burn more fat during exercise (by high fat diets) can make one less economical/efficient (which is the opposite to "super shoes" which improve running economy), competing with social media...
2022-07-2358 minInside ExerciseGlucose metabolism, exercise and the liver with Dr David WassermanDr Glenn McConell chats with Professor David Wasserman from Vanderbilt University in Nashville, Tennessee, USA. David is recognised as an absolute authority on glucose homeostasis. His research focuses on how the system acts to protect sugar levels during exercise and disease. This talk is wide ranging with a focus on the liver. We discuss the large range of roles of the liver, how it maintains blood glucose levels at rest and in particular during exercise. The role of circulating hormones in the regulation of liver glucose output during exercise is a focus. Professor Wasserman has been at the forefront o...
2022-07-1752 minInside ExerciseHow did Kipchoge break 2 hrs for the marathon?! With Dr Andy JonesDr Glenn McConell chats with Professor Andy Jones from the University of Exeter in England about the incredible Eliud Kipchoge and what it took for him to break 2 hr for the marathon distance. Professor Jones, who has an exception research track record, conducted a study with 16 world class marathon runners to determine what factors are required to run a marathon in 2 hr. He then used this data and other information he had to choose which runners would attempt Breaking2 in Monza in 2017. We discuss this attempt and Eliud Kipchoge’s eventual breaking of 2 hr in Vienna in 2019. Andy outlines the...
2022-07-1158 minInside ExerciseIs high intensity interval training (HIIT) the best way to train? With Dr Marty GibalaDr Glenn McConell chats with Professor Marty Gibala from McMaster University in Canada about the physiological effects of high intensity interval training (HIIT) compared with continuous submaximal exercise training. Comparisons between the effects of HIIT and sprint interval training (SIT) are also discussed. The immense interest in HIIT was initiated by a ground breaking study that Marty conducted in 2005 comparing HIIT to submaximal exercise training. He has since been at the forefront of the area. The discussion focussed on HIIT vs SIT vs continuous submaximal exercise in regards to aerobic capacity, exercise performance, cardiovascular function, weight loss, insulin sensitivity a...
2022-07-061h 02
Inside ExerciseExercise and type 1 diabetes with Dr Michael RiddellDr Glenn McConell chats with Professor Michael Riddell from York University in Canada who is the number 1 exercise and type 1 diabetes (T1D) researcher in the world. Michael has T1D as does his son which has greatly motivated him in his research. We discuss a lot of aspects of T1D and exercise including what is T1D, the effect of T1D on exercise metabolism and on health, the beneficial effects of exercise in people with T1D, the importance of continuous glucose monitors and insulin pumps, and how some people with T1D are increasingly developing c...
2022-06-3058 min
Inside ExerciseDoes exercise slow aging? With Dr Bret GoodpasterDr Glenn McConell chats with Professor Bret Goodpaster from Advent Health in Florida, USA on exercise and aging. Bret has undertaken ground breaking work on the factors contributing to insulin resistance and aging and the role of exercise to overcome insulin resistance and slow aging. We discuss these aspects with a focus on skeletal muscle. Bret points out that physiological reserve can become critically low with age and that exercise builds a buffer so that activities of everyday living can be continued well into old age.
Inside Exercise brings to you the who's who of exercise metabolism, exe...
2022-06-2349 minInside ExerciseNitrate and exercise with Dr Andrew CogganDr Glenn McConell chats with Associate Professor Andrew Coggan who is a very highly regarded exercise metabolism researcher and also THE guru of using power with cycling exercise training. After a brief chat about his background and cycling prowess and the use of cycling power, we focus on his research on nitrate and whether nitrate supplementation via beetroot ingestion improves strength and exercise performance.
Twitter: @inside_exercise, @AndrewCoggan1, @GlennMcConell1.
Inside Exercise brings to you the who's who of exercise metabolism, exercise physiology and exercise’s effects on health. With scientific rigor, these researchers discuss popular exe...
2022-06-231h 09
Mission Evolution with Gwilda WiyakaME: Dr. Glenn T Martin - Evolving Into A Unified WorldGlen T. Martin, Ph.D., is Professor of Philosophy at Radford University. He is President of the World Constitution and Parliament Association (WCPA), a global organization that sponsors the Constitution for the Federation of Earth. He has lectured worldwide on behalf of the Earth Constitution.His several peace awards include the GUSI Peace Prize International in 2013. He has published many articles and eleven books, including Global Democracy and Human Self-Transcendence.Become a supporter of this podcast: https://www.spreaker.com/podcast/mission-evolution-with-gwilda-wiyaka--2888020/support.Please note that all XZBN radio and/or television shows are Copyright © R...
2019-05-081h 00