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PUTOKAZ25. Hfz. Sead ef. Subašić- Akif ef. Skenderović- djed i daija, Medresa i Qasim& Iskušenje gubitka majkeU dvadesetpetoj epizodi našeg i vašeg podcasta "Putokaz" imali smo čast da ugostimo hafiza Seada ef. Subašića. Hafiz potječe iz jedne veoma poznate ulemanske porodice i predstavlja eklatantan primjer insana odgojenog u zdravoj porodici. Rođen je u Štutgartu u Njemačkoj, gdje je i završio osnovnu školu. Prvi dio razgovora smo posvetili upravo temi života i odlaska u Njemačku mladih ljudi, organiziranosti muslimana, broju konvertita... Hafiz Sead je sin jednog od najpoznatijih imama u dijaspori Hamze ef. Subašića, i unuk dr. Akif ef. Skenderovića, prvog doktora islamskih nauka sa područja bivše J...2023-01-241h 17
Media DiversifiedThe Forde Report"The Forde Report is a damning document which highlights a deeply toxic and unpleasant culture in the Labour Party that allows racism from senior officials to go unchallenged." - Taj Ali
Taj Ali our host was joined by broadcasters and writers and journalists Perry Blankson, Ayaz Rafik, Hamza Ali Shah, Rachel Shabi, Afroze Zaidi, Beauty Dhlamin, Labour councillor and anti-racism equalities campaigner Shaista Aziz, and author and broadcaster Genelle Aldred
Ahaed of the debate, Genelle said "The Forde report demands a response. Many Black people in the UK say they now feel politically homeless, especially those...2022-07-281h 26
MCAT Modules - Review8:3. DNA Libraries and Generating cDNAProt —> mRNA —> cDNA —> dsDNA. (Step 2 via reverse transcriptase and step 3 via DNA Polymerase). Now the dsDNA is injected into a virus which infects bacteria to make lots of the DNA.2020-08-1504 minMCAT Modules - Review8:2. Polymerase Chain ReactionDenaturation (Heat to high temp), Primer Annealing (Cool slightly), Primer Extension via polymerase (Heat but not as much as step 1).2020-08-1506 minMCAT Modules - Review8:1. Gel ElectrophoresisGE find us the length of a DNA Strand (how many base pairs long).2020-08-1506 minMCAT Modules - Review7:5. Applying the HP EquationNot really sure why I did a module on this - basically you know they’re homo recessive because they have blue eyes (the recessive trait), and you know to use q BECAUSE we’re dealing with the recessive trait.2020-08-1001 minMCAT Modules - Review7:4. The Hardy-Weinberg EquationHP Equation gives P(allele frequencies). P^2 is probability of homo dominant, Q^2 is probability of homo recessive, 2pq is probability of heterozygous allele combo. P = frequency of dom allele, Q = frequency of recessive allele.2020-08-1002 minMCAT Modules - Review7:3. Worked Example: Punnett SquaresDiscusses Dihybrid Crosses and the Law of Independent Assortment.2020-08-1006 minMCAT Modules - Review7:2. Co-dominance and Incomplete DominanceDon’t let the title fool you. This is short. Discusses complete, incomplete, and co-dominance.2020-08-1000 minMCAT Modules - Review7:1. An Introduction to Mendelian GeneticsDiscuss genes, alleles, geno/phenotypes, and punnet squares. The Khan Academy video discusses the history (Gregor Mendel) but let’s be real, who cares.2020-08-1006 minMCAT Modules - Review6:5. The Effects of MutationsMutations can be good, bad, or both.2020-08-1002 minMCAT Modules - Review6:4. Mutagens and CarcinogensDefine mutagens and then discuss endogenous and exogenous mutagens. (Endo: ROS); (Exo: intercalators, base analogues, carcinogens)2020-08-1008 minMCAT Modules - Review6:3. The Causes of Genetic MutationsSmall scale mutations (point: TTM; frame-shift: ID) and Large-scale mutations (translocation, inversion).2020-08-0410 minMCAT Modules - Review6:2. The Different Types of MutationsPoint, Frame Shift, and Nonsense vs. Missense. Further divided Missense to Silent, Conservative, and Non-Conservative.2020-08-0408 minMCAT Modules - Review6:1. Introduction to Genetic MutationsClarifies that mutations arise at the DNA level, and from where mutations originate.2020-08-0304 minMCAT Modules - Review5:7. Tumor SuppressorsDiscusses categories of tumor suppressors and then 2 examples: pRb and p53, both proteins.2020-08-0309 minMCAT Modules - Review5:6. OncogenesDiscusses the 3 mechanisms through which oncogenes are formed from proto-oncogenes, and types of oncogenes with examples.2020-08-0321 minMCAT Modules - Review5:5. Non-Coding RNAI discuss ncRNAs (RNA that’s ready to perform tasks w/o becoming protein) and then move onto rRNA, tRNA, miRNA, snRNA, and snoRNA. Have fun with all these acronyms lol2020-07-2713 minMCAT Modules - Review5:4. Post-Transcriptional RegulationNot really an important module but skip to 6:18 for new stuff (RNA Editing via the ADAR and CDAR Enzymes)2020-07-2008 minMCAT Modules - Review5:3. Regulation of TranscriptionDiscusses GTFs, then discusses activators/repressors and enhancers/silencers. Finally distinguishes between regulation of transcriptional euk and prok organisms.2020-07-1917 minMCAT Modules - Review5:2. DNA and Chromatin RegulationDiscusses HAT and HDAC enzymes to uncoil/coil DNA (uncoil = activate for transcription) then transitioned into DNA methylation as it relates to CpG Islands and MBB’s.2020-07-1817 minMCAT Modules - Review5:1. The Lac Operon - Part 2More terminology of the Lac Operon mechanism, refined ideas from the first part.2020-06-3013 minMCAT Modules - Review4:16. DNA Structure and Function (Random Info)End of chapter random info (as I’ve done before). Although pay attention to end where I discuss donor:acceptor ratios of nucleobases.2020-06-3008 minMCAT Modules - Review4:15. The Jacob Monod Lac OperonDiscusses why gene expression regulation occurs @ transcription level. Discusses the Jacob Monod Lac Operon’s structure (ZYA) and function (lactose metabolism) and how the repressor (@operator site) controls this process.2020-06-3014 minMCAT Modules - Review4:14. Protein ModificationLISTEN @ 2x speed (on Apple podcasts). Discusses co- and post-translational modifications (GLUMPP) which occur for those proteins that aren’t fully ready to work even after translation finishes.2020-06-2730 minMCAT Modules - Review4:13. Semi-Conservative ReplicationDiscusses the conservative (Incorrect), dispersive(Incorrect), and Semi-Conservative (Correct) theories of replication.2020-06-2602 minMCAT Modules - Review4:12. DNA Repair 2 (response to Dimers) + Summary of BOTH DNA RepairsDiscuss endo- and exogenous factors that damage DNA, the process of Nucleotide Excision Repair (NER), and what happens when NER fails.2020-06-2618 minMCAT Modules - Review4:11. DNA Repair 1 (response to Mutations)(This is where the modules get longer/content heavy). Discusses exo- and endonucleases as well as the Mismatch Repair Mechanism as a physiological fail safe.2020-06-2419 minMCAT Modules - Review4:10. Differences in translation between prokaryotes and eukaryotesStrand structure, protection factors (proks have none), and starting A2 (proks = fmet // euks = met)2020-06-2209 minMCAT Modules - Review4:9. TranslationDiscusses the process using the APE Sites.2020-06-2207 minMCAT Modules - Review4:8. Speed and Precision of DNA ReplicationUSELESS MODULE // I didn’t think I’d actually get it to 45 seconds LOL2020-06-2100 minMCAT Modules - Review4:7. Transcription and mRNA ProcessingI know we talked about this in 4:1 but this has more detail. Distinguishes between eukaryotic and prokaryotic transcription and reviews eukaryotic transcription in detail (with processing).2020-06-2115 minMCAT Modules - Review4:6. The DNA Replication Process(Yes it has a different name). The 8-step process.2020-06-2104 minMCAT Modules - Review4:5. Telomeres and Single Copy DNA vs. Repetitive DNAIntroduce telomeres as “protective caps” to ensure protection and quality replication of DNA sequences. Also discuss single copy DNA (important for genetic info) vs repetitive DNA (telomeres are an example of this).2020-06-1911 minMCAT Modules - Review4:4. Antiparallel Structure of DNA StrandsThe strands (each of the 2 sugar phosphate backbones) run in opposite directions. That is all.2020-06-1903 minMCAT Modules - Review4:3. Molecular Structure of DNAReally just a recap of the previous module + the types of bonding that forms the Double Helix2020-06-1904 minMCAT Modules - Review4:2. DNA (Overview)Discuss DNA’s basic structure as well as the nitrogenous base pairs.2020-06-1904 minMCAT Modules - Review4:1. Eukaryotic gene transcription (DNA —> RNA)(Content heavy!) Transcription, Structural Differences of Nucleic Acids, mRNA Processing, and RNA Interference2020-06-1718 minMCAT Modules - Review3:7. The Lineweaver-Burke PlotSearch up the Lineweaver-Burke Plot on your own.2020-06-1601 minMCAT Modules - Review3:6. Covalent Modifications to EnzynesCovalent Modifications are changes made to a protein to accomplish a variety of tasks (activate, deactivate, etc). I discuss Small Post-translational Modifications, Zymogens, and Suicide Inhibitors.2020-06-1611 minMCAT Modules - Review3:5. Non-enzymatic Protein FunctionMARTI (Motor, Antibodies, Receptors, Transport, and Ion Channel) Proteins. Don’t forget LITHOL for types of enzymes.2020-06-1511 minMCAT Modules - Review3:4. Allosteric Regulation and Feedback LoopsDiscuss allostery, feedback loops, and the phosphofructokinase enzyme and it how it is involved in a feedback loop. (Pretty long module)2020-06-1415 minMCAT Modules - Review3:3. Cooperativity (or Cooperative Binding)Details positive, negative, and noncooperation binding.2020-06-1108 minMCAT Modules - Review3:2. Steady States and the Michaelis-Mentin EquationDiscusses the steady state assumption and its equation, the MM Equation, and the catalytic efficiency equation. Also notes Kcat and Km and their interpretations.2020-06-1112 minMCAT Modules - Review3:1. An Introduction to Enzymes KineticsI discuss the 3 assumptions that allow for the (many) conclusions we will reach later in this season.2020-06-1110 minMCAT Modules - Review2:7. Enzymes and their Local EnvironmentThe effects of the pH and Temperature factors on catalysis.2020-06-1105 minMCAT Modules - Review2:6. Cofactors, Coenzymes, and VitaminsWhat they are and some examples. Discuss his minerals as well.2020-06-1105 minMCAT Modules - Review2:5. Six Types of EnzymesLITHOL // Transferase, ligase, oxidoreductase, isomerase, hydroplane, lyase2020-06-1111 minMCAT Modules - Review2:4. Induced Fit Model of Enzyme CatalysisDetails active and allosteric site binding and distinguishes between reaction and regulation.2020-06-0907 minMCAT Modules - Review2:3. Enzymes and Activation EnergyDetails how catalysts affect a reaction.2020-06-0904 minMCAT Modules - Review2:2. Intro to Enzymes and CatalystsIt’s in the title.2020-06-0804 minMCAT Modules - Review2:1. Enzyme Structure and FunctionDiscusses catalytic conditions and collision theory.2020-06-0801 minMCAT Modules - Review1:10. The Structure and Function of Globular ProteinsNotes on the final module from this chapter (Amino Acids and Proteins).2020-06-0808 minMCAT Modules - Review1:9. Conformational Stability: Protein Folding and DenaturationDistinguish between activated and deactivated proteins and how each form is reached.2020-06-0807 minMCAT Modules - Review1:8. 4 Levels of Protein StructureDiscusses the four levels of protein structure and what factors allow for distinction between them.2020-06-0705 minMCAT Modules - Review1:7. Classification of Amino AcidsFILLER EPISODE2020-06-0500 minMCAT Modules - Review1:6. Isoelectric Point (pI) and ZwitterionsDiscuss pI in relation to pH and Zwitterions.2020-06-0406 minMCAT Modules - Review1:5. Amino Acid StructureStructure of Amino Acids2020-06-0402 minMCAT Modules - Review1:4. Special Cases: His, pro, gly, cysI elaborate on special cases in Amino Acids.2020-06-0407 minMCAT Modules - Review1:3. Peptide Bond - Formation and CleavageI detail how peptide bonds are formed (NYC-add-slim) and cleaved (specific and nonspecific methods).2020-06-0306 minMCAT Modules - Review1:2. Central Dogma - RevisitedShould really be titled “Exception to the Dogma”. I detail 4 processes that violate the Central Dogma.2020-06-0306 minMCAT Modules - Review1:1. Central Dogma of Molecular BiologyDetails what the dogma states and what it specifies.2020-06-0202 minMCAT Modules - ReviewMCAT Modules - Review (Trailer)2020-06-0200 min