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JHLT: The PodcastJHLT: The PodcastEpisode 63: Severe PGD Using DCD HeartsOn this episode of JHLT: The Podcast, the Digital Media Editors invite first author Peter Cho and senior author Abbas Ardehali, MD, to discuss the paper, “Severe primary graft dysfunction in heart transplant recipients using donor hearts after circulatory death: a United States Experience.” Peter is a third year medical student at Drexel University, and Dr. Ardehali is professor of surgery and medicine and the Director of the Heart, Lung, and Heart-Lung Transplant programs at UCLA. The episode explores: The study's findings regarding an increased incidence of severe PGD at 24 hours post-transplant in DCD over...2025-05-0712 minJHLT: The PodcastJHLT: The PodcastEpisode 62: Apixaban Plasma Levels in Patients with HeartMate 3Returning for a second study this month, the JHLT Digital Media Editors invite first author Charlotte Van Edom to discuss the paper, “Apixaban plasma levels in patients with HeartMate 3 support.” As a cardiologist in training and a PhD candidate at the University Hospitals Leuven in Belgium, Van Edom’s work focuses on hemocompatibility and mechanical circulatory support, covering both short-term and long-term support. The episode explores: The evolution of the use and understanding of direct oral anticoagulants (DOACs) during LVAD support, including the increased focus on Factor Xa inhibitors Encouraging findings from the study and wh...2025-04-1012 minJHLT: The PodcastJHLT: The PodcastEpisode 61: Is Sotatercept safe in patients with PAH?On this episode of JHLT: The Podcast, the Digital Media Editors invite author Ioana Preston, MD, to discuss the paper, “Efficacy and safety of sotatercept across ranges of cardiac index in patients with pulmonary arterial hypertension: A pooled analysis of PULSAR and STELLAR.”   Dr. Preston is the director of the pulmonary hypertension center at Lahey Hospital and Medical Center in Burlington, Massachusetts, and has over 20 years of experience in caring for patients with PH, as well as multiple clinical trials in PH.   The episode explores: What makes sotatercept unique as the fi...2025-04-0213 minJHLT: The PodcastJHLT: The PodcastEpisode 60: Riociguat in patients with PAH and Cardiometabolic ComorbiditiesReturning for a second study this month, the JHLT Digital Media Editors conduct an internal discussion on the paper, “Safety and efficacy of riociguat in patients with pulmonary arterial hypertension and cardiometabolic comorbidities: Data from interventional clinical trials.”   The episode explores: The aging PAH population and the new comorbidities that must be considered in research How the study augments and expands on recent standards, like the 2022 ESC/ERS guidelines for pulmonary hypertension Limitations on the study and opportunities for future research For the latest studies from JHLT, visit www.jhltonline.org/current, or, if yo...2025-03-1807 minJHLT: The PodcastJHLT: The PodcastEpisode 59: Rewarming Ischemia Time in Lung TransplantationOn this episode of JHLT: The Podcast, the Digital Media Editors invite lead author Jan Van Slambrouck, MD, to discuss the paper, “The effect of rewarming ischemia on tissue transcriptome and metabolome signatures: A clinical observational study in lung transplantation.”   Dr. Van Slambrouck is a general surgeon who’s just finished his PhD training at the KU Leuven lab of respiratory disease and thoracic surgery in Belgium.   The episode explores:  How rewarming ischemia time (RIT) affects donor lungs, especially on the molecular level The pace of rewarming and how prior literatur...2025-03-0513 minJHLT: The PodcastJHLT: The PodcastEpisode 58: Sympathetic ReinnervationReturning for a second study this month, the JHLT Digital Media Editors invite lead author Oliver J.F. Weiner, to discuss the paper, “Sympathetic reinnervation in cardiac transplant recipients: Prevalence, time course, and association with long-term survival.” Dr. Weiner is currently an out of training registrar at Monash Health in Melbourne, Australia, but will soon return to his home of the UK to begin internal medicine training with the intention becoming a cardiologist. He is especially interested in advanced heart failure and electrophysiology. The episode explores: The uncertainty around clinical influences on reinnervation The impo...2025-02-2012 minJHLT: The PodcastJHLT: The PodcastEpisode 57: Trends and Outcomes in EVLPOn this episode of JHLT: The Podcast, the Digital Media Editors invite lead author Jonathan E. Williams, MD, to discuss the paper, “Ex-Vivo Lung Perfusion: National Trends and Post-Transplant Outcomes.” Dr. Williams is a general surgery resident at the University of Michigan in Ann Arbor, with work focusing on contemporary lung preservation strategies, perfusion techniques, and particularly, EVLP. The episode explores: How the study explores the theory that EVLP use may increase transplant volumes Preserving data quality and other study limitations How to work in fields of study that sometimes yield as many questions as a...2025-02-0512 minJHLT: The PodcastJHLT: The PodcastEpisode 56: The Best Studies of 2024JHLT: The Podcast returns with a year-end recap of 2024. Each Digital Media Editor shares one of their favorite studies from JHLT in 2024 for a quick recap of last year’s excellent science in advanced heart and lung disease. Studies featured: ·         Cardiac magnetic resonance assessment of acute rejection and cardiac allograft vasculopathy in pediatric heart transplant Kikano, Sandra et al. JHLT May 2024 5(43):745-754 ·         A modular simulation framework for organ allocation Rose, Johnie et al. JHLT Aug 2024 8(43):1326-1335. ·         HeartMate 3 Snoopy: Noninvasive cardiovascular diagnosis of patients with fully magnetically levitated blood pumps during echocardiographic spee...2025-01-1611 minJHLT: The PodcastJHLT: The PodcastEpisode 55: Meet the Editors!Happy new year from JHLT: The Podcast! On this episode, the Digital Media Editors are joined by ISHLT Director of Marketing + Communications Jess Burke, CAE, to share a little bit about themselves and their backgrounds. Hear about how each of the JHLT Digital Media Editors got involved in transplantation and a little about each of their research and personal interests. For the latest studies from JHLT, visit www.jhltonline.org/current, or, if you’re an ISHLT member, access your Journal membership at www.ishlt.org/jhlt. Don’t already get the Journal? Join...2025-01-0816 minJHLT: The PodcastJHLT: The PodcastEpisode 54: Long-term follow up on the SCHEDULE trialOn the second December episode of JHLT: The Podcast, the Digital Media Editors explore another paper from the December issue of JHLT, entitled “Long-term follow-up of the randomized, prospective Scandinavian heart transplant everolimus de novo study with early calcineurin inhibitors avoidance (SCHEDULE) trial.” First author Entela Bollano, MD, PhD, and senior author Niklas Bergh, MD, PhD, both from the Sahlgrenska University Hospital in Sweden, join the podcast to discuss their work. You’ll hear about: Past outcomes of the SCHEDULE trial, including reduced CAV in patients on everolimus over patients on CNIs How this study...2024-12-1815 minJHLT: The PodcastJHLT: The PodcastEpisode 53: Pollution exposure in the first 3 months post-lung transplantOn this episode of JHLT: The Podcast, the Digital Media Editors invite lead author Chung-Wai Chow, MD, PhD, FRCPC, to discuss the paper, “Pollution exposure in the first 3 months post transplant is associated with lower baseline FEV1 and higher CLAD risk.” Dr. Chow is a transplant pulmonologist and clinician scientist at the University of Toronto, with work focusing on investigating air pollution’s impact on chronic lung diseases and developing improved methods to assess lung function. The episode explores: Measurement methods for home and personal air pollution exposures Specific pollutants like black carbon and their...2024-12-0412 minJHLT: The PodcastJHLT: The PodcastEpisode 52: State of the art review on aortic Insufficiency in durable LVADsOn the second November episode of JHLT: The Podcast, the Digital Media Editors continue MCS-month with a paper from the November issue of JHLT, entitled “Aortic insufficiency in the patient on contemporary durable left ventricular assist device support: A state-of-the-art review on perioperative and postoperative assessment and management.”  First author Diyar Saeed, MD, PhD, of the Heart Center Niderrhein, and senior author Jennifer Cowger, MD, MS, of Henry Ford Hospitals both join the podcast. You’ll hear about: Why LVAD patients develop new and progressive aortic regurgitation—and how contemporary devices may differ Associated hemodynam...2024-11-2015 minJHLT: The PodcastJHLT: The PodcastEpisode 51: Can you be pragmatic about tMCS in Acute RV Failure?On this episode of JHLT: The Podcast, the Digital Media Editors have three expert guests to discuss their paper, “Pragmatic approach to temporary mechanical circulatory support in acute right ventricular failure.” You’ll hear from first author Anthony Carnicelli, MD, from the Medical University of South Carolina; Alexander Bernhardt, MD, from the University Hospital Hamburg-Eppendorf; and senior author Manreet Kanwar, MD, of the Cardiovascular Institute at Allegheny Health Network. The episode explores: Parameters that influence deciding when to escalate RV support Determining which device is right for each patient Evaluating a patient for the correc...2024-11-0621 minJHLT: The PodcastJHLT: The PodcastEpisode 50: Age matching lung donors and recipients in EuropeOn this episode of JHLT: The Podcast, the Digital Media Editors discuss a paper from the October issue of JHLT, entitled “Donor to recipient age matching in lung transplantation: A European experience.” Senior author Andrew Fisher, FRCP, PhD joins the podcast to discuss the paper. You’ll hear about: European practices in lung transplantation and the donor population Main findings and takeaways How age disparities in donor matching affect outcomes Extended criteria for older donors For the latest studies from JHLT, visit www.jhltonline.org/current, or, if you’re an ISHLT member, access your Journal m...2024-10-1616 minJHLT: The PodcastJHLT: The PodcastEpisode 49: The Evaluation and Care of Cardiac Transplant CandidatesOn this episode of JHLT: The Podcast, the Digital Media Editors discuss a new guidelines document from the ISHLT entitled “The 2024 ISHLT Guidelines for the Evaluation and Care of Cardiac Transplant Candidates.” The lead co-authors of the document—Yael Peled, MD, and Anique Ducharme, MD, MSc—are on the podcast to discuss the document. You’ll hear about: Challenges in drafting such an overarching document Highlights for clinicians Major changes in the document since the last version How changes in durable and temporary MCS affect use of the document For the latest studies from JHLT...2024-10-0216 minJHLT: The PodcastJHLT: The PodcastEpisode 48: A Tribute to Daniel R GoldsteinThis month, JHLT: The Podcast reissues our September 2023 tribute to former Editor-in-Chief, Dr. Daniel R. Goldstein. Dr. Goldstein stepped down from his role for health reasons in July 2023; he had been diagnosed with an advanced salivary gland malignancy and felt he would be unable to continue serving JHLT and the International Society for Heart and Lung Transplantation (ISHLT) to his characteristically demanding standard. Sadly, Dr. Goldstein died on 21 May, 2024, at the age of 56, leaving behind his wife, 2 children, an extended family, and a larger universe of colleagues, collaborators, and mentees who greatly benefited from his equanimity, wisdom...2024-09-1314 minJHLT: The PodcastJHLT: The PodcastEpisode 47: An Interview with JHLT EIC Joe RogersIn this special episode of JHLT: The Podcast, the Digital Media Editors connect with Joseph Rogers, MD, the new Editor-in-Chief of JHLT. In the conversation, Dr. Rogers shares more about his vision for the Journal, how he plans to tackle the challenges and opportunities facing the publication, and a little about his life both inside and outside of medicine. In addition to being the new Editor-in-Chief, Dr. Rogers is the President and CEO of the Texas Heart Institute in Houston, a past president of the ISHLT, and a prolific contributor to the field of heart...2024-09-0425 minCTSNet PodcastsCTSNet PodcastsThe Beat With Joel Dunning Ep. 70: EACTS 2024This week on The Beat, Editor in Chief Joel Dunning discusses the 38th EACTS Annual Meeting in Lisbon.  He provides a comprehensive overview of the conference, including details about the featured speakers and the topics to be addressed by these distinguished surgeons.  He also discusses operating room extubation for patients undergoing cardiac surgery, how small airway brush gene expression predicts chronic lung allograft dysfunction and mortality, strategies to prevent and manage hemocompatibility-related adverse events in VAD patients, and mentoring pediatric heart surgeons.  In addition, Joel discusses a beating heart implant technique in donation after circulatory dea...2024-08-2932 minJHLT: The PodcastJHLT: The PodcastEpisode 46: August 2024On the second August episode of JHLT: The Podcast, the Digital Media Editors discuss a paper from the August issue of JHLT, entitled “A modular simulation framework for organ allocation.”The episode is hosted by Digital Media Editor Erika Lease, MD, FCCP, a transplant pulmonologist from the University of Washington.   The guests for this episode are first author Johnie Rose, MD, PhD, of the Center for Community Health Integration at Case Western Reserve University School of Medicine, and lead author Maryam Valapour, MD, MPP, of the Department of Pulmonary Medicine at the Cleveland Clinic.  2024-08-1423 minJHLT: The PodcastJHLT: The PodcastEpisode 45: August 2024On this episode of JHLT: The Podcast, the JHLT Digital Media Editors discuss a brand new consensus document from the ISHLT entitled “Strategies to Prevent Hemocompatibility Related Adverse Events in Patients with a Durable, Continuous-Flow Ventricular Assist Device.” The episode is hosted by Digital Media Editor Erika Lease, MD, FCCP, a transplant pulmonologist from the University of Washington.   The consensus document’s lead author, Ian Hollis, PharmD, a heart failure pharmacist and Associate Professor from the University of North Carolina in Chapel Hill, joins the podcast to discuss the document.  During the discussion, he’s reunited w...2024-08-0719 minCardioScripts PodcastCardioScripts PodcastACC/ISHLT 2024 Recap (Part 3)This episode is a rebroadcast of the ACCP Cardiology PRN webinar where Drs. Vicki Groo and Ian Hollis reviewed several different presentations from the ACC and ISHLT meetings. 2024-07-0922 minJHLT: The PodcastJHLT: The PodcastEpisode 44: July 2024On this episode of JHLT: The Podcast, the JHLT Digital Media Editors explore two studies from the July issue of The Journal of Heart and Lung Transplantation. Digital Media Editor Marty Tam, MD, a transplant cardiologist from the University of Michigan in Ann Arbor, hosts this episode.   First, Dr. Tam and Digital Media Editor Erika Lease, MD, FCCP, interview their first guest, Daniel Calabrese, MD, first author on the study “Macrophage and CD8 T cell discordance are associated with acute lung allograft dysfunction progression.” The study’s authors sought to tackle challenges behind early detection of chro...2024-07-0326 minCardioScripts PodcastCardioScripts PodcastACC/ISHLT 2024 Recap (Part 2)This episode is a rebroadcast of the ACCP Cardiology PRN webinar where Drs. Kristen De Almeida and Augustus (Rob) Hough reviewed the DANGER-SHOCK and ULTIMATE-DAPT trials released at the ACC 24 meeting. The views expressed in this presentation reflect those of the presenter, and not necessarily those of the Department of Veterans Affairs or Public Health Service.2024-06-1816 minJHLT: The PodcastJHLT: The PodcastEpisode 43: June 2024On this episode of JHLT: The Podcast, the JHLT Digital Media Editors explore two studies from the June issue of The Journal of Heart and Lung Transplantation. Digital Media Editor Van-Khue Ton, MD, a transplant cardiologist from Massachusetts General Hospital, hosts this episode.   First, Dr. Ton and Digital Media Editor Marty Tam, MD, interview their first guests, first author Matthew Carey, MD, MBA, and senior author Justin Fried, MD, both of the Columbia University Irving Medical Center in New York City, on their study “Aortic Root Thrombosis in patients with HeartMate 3 left ventricular assist device sup...2024-06-0522 minCardioScripts PodcastCardioScripts PodcastACC/ISHLT 2024 Recap (Part 1)This episode is a rebroadcast  of the ACCP Cardiology PRN webinar where Drs. Tracy Macaulay and Bill Larsen reviewed the REDUCE-AMI and EMPACT-MI trials released at the ACC 24 meeting. 2024-06-0418 minEvery Possible AngleEvery Possible AngleReaching a Consensus: A Change in Heart Procurement with Dr. Hannah CopelandIn this episode, we're joined by the remarkable Dr. Hannah Copeland, one of the foundational authors of the notable ISHLT Consensus Statement on Donor Heart and Lung Procurement. Dr. Copeland has contributed to numerous research publications on various cardiac topics, with a remarkable emphasis on standardizing the many common variables that can shift the circumstances of a case. Thanks for listening! Sitting down to watch? Find the episodes on our YouTube Channel.Interested in learning more about other innovations in transplant? Follow Paragonix Technologies on LinkedIn for relevant news, events, and upcoming episodes. 2024-05-2250 minJHLT: The PodcastJHLT: The PodcastEpisode 42: May 2024On this episode of JHLT: The Podcast, the JHLT Digital Media Editors explore two studies from the May issue of The Journal of Heart and Lung Transplantation. Digital Media Editor David Schibilsky, MD, a cardiothoracic surgeon from Freiburg, Germany, hosts this episode.   First, Dr. Schibilsky and Digital Media Editor Erika Lease, MD, interview their first guest, Helen A. Hannan, the podcast’s first-ever undergraduate pre-medical guest, from the University of Michigan. Helen was the lead author on the study “Racial and Gender Disparities in Transplantation of Hepatitis C+ Hearts and Lungs.” The study noted that prior r...2024-05-0128 minHeart Failure BeatHeart Failure BeatIs ACHD just HF by a different name?On the April episode of the Heart Failure Beat, Priya and Michael take on adult congenital heart disease (ACHD) with guests Chetan Pasrija, MD, MS, and Ari Cedars, MD, and discover that it’s never too early to refer a patient with ACHD for advanced therapies. Andrew Sauer, MD, an associate editor of the Journal of Cardiac Failure, joins the episode for a new segment featuring a review of a recently published article on the STRONG-HF trial. Priya does a fast-track review of 4 trials in 4 minutes from ACC.24 and the ISHLT 44th Annual Meeting and Scientific Sessions on From Failure...2024-04-2650 minEvery Possible AngleEvery Possible AngleDriven by Science: Moving Transplantation Forward with Dr. Andreas ZuckermannIn this episode, we're joined by the remarkable Dr. Andreas Zuckermann, a luminary in the realm of transplantation. Dr. Zuckermann takes us on a journey through his distinguished career, from transplant coordinator to cardiac surgeon to ISHLT President, shedding light on his pivotal contributions to the field. In honor of the recent ISHLT conference held this month in Prague, we also delve into the genesis of the GUARDIAN clinical registry, the largest prospective registry in transplantation aimed at propelling the science of transplantation to new heights. Thanks for listening! Sitting down to watch? Find the episodes on o...2024-04-2235 minJHLT: The PodcastJHLT: The PodcastEpisode 41: April 2024On this episode of JHLT: The Podcast, the JHLT Digital Media Editors explore two studies from the April issue of The Journal of Heart and Lung Transplantation. Digital Media Editor Erika Lease, MD, a transplant pulmonologist at the University of Washington in Seattle, hosts this episode.   First, Dr. Lease and Digital Media Editor Van-Khue Ton, MD interview their first guests, Paul J. Scheel III, MD and Steven Hsu, MD, both of Johns Hopkins University. Dr. Scheel was first author and Dr. Hsu was senior author on the study “Occult right ventricular dysfunction and right ventricular-vascular unc...2024-04-0325 minJHLT: The PodcastJHLT: The PodcastEpisode 40: March 2024On this episode of JHLT: The Podcast, the JHLT Digital Media Editors explore two studies from the March issue of The Journal of Heart and Lung Transplantation. Digital Media Editor Marty Tam, MD, an advanced heart failure and transplant cardiologist at University of Michigan in Ann Arbor, hosts this episode.   First, Dr. Tam and Digital Media Editor David Schibilsky, MD interview their first guests, Fiorella Calabrese, MD and Francesca Lunardi, MD, ScD, PhD, of University of Padova, in Padova Italy. Dr. Lunardi was first author and Dr. Calabrese was senior author on the study “Assessing the...2024-03-0628 minJHLT: The PodcastJHLT: The PodcastEpisode 39: February 2024On this episode of JHLT: The Podcast, the JHLT Digital Media Editors explore two studies from the February issue of The Journal of Heart and Lung Transplantation. Digital Media Editor Van-Khue Ton, MD, a transplant cardiologist at Massachusetts General Hospital, hosts this episode.   First, Dr. Ton and Digital Media Editor Erika Lease, MD interview their first guest, David Jenkins, FRCS(Cth), of the Royal Papworth Hospital in Cambridge, UK. Dr. Jenkins was senior author on the study “Perioperative extracorporeal membrane oxygenation support for pulmonary endarterectomy: A 17-year experience from the UK national cohort.” In the conve...2024-02-0726 minTHE MCCULLOUGH REPORTTHE MCCULLOUGH REPORTShould Renal Transplantation require COVID-19 vaccination?The McCullough Report with Dr. Peter McCullough – Each transplant rejection episode is a step closer to death. So the questions on the table are:  1) how long will COVID-19 vaccination remain in organ transplant programs?  2) will ISHLT - International Society for Heart and Lung Transplantation analyze the loss of life BEFORE and AFTER transplantation attributable to COVID-19 vaccination? 3) will transplant directors ever reverse course and admit vaccination was a mistake? 4) will doctors and...2024-01-3057 minJHLT: The PodcastJHLT: The PodcastEpisode 38: January 2024Welcome to 2024! The JHLT Digital Media Editors kick off the new year with a look back at the best of the best from 2023 – specifically, a few of the guidelines and consensus statements from the International Society for Heart and Lung Transplantation that appeared in The Journal of Heart and Lung Transplantation this past year.   Digital Media Editor David Schibilsky, MD, a cardiothoracic surgeon from Freiburg, Germany, hosts this episode.   First, Digital Media Editor Marty Tam, MD, reviews the updated Heart Transplantation guidelines, published in JHLT at the start of 2023. What’s change...2024-01-0316 minJHLT: The PodcastJHLT: The PodcastEpisode 37: December 2023In our final episode of 2023, the JHLT Digital Media Editors have two manuscripts from the December 2023 issue of The Journal of Heart and Lung Transplantation! Digital Media Editor Erika Lease, MD, transplant pulmonologist at the University of Washington in Seattle, hosts this episode.   First, a free-ranging conversation with first author Mark E. Snyder, MD, and senior author John F. McDyer, MD, on their team’s study “Impact of age and telomere length on circulating T cells and rejection risk after lung transplantation for idiopathic pulmonary fibrosis.”   A subset of patients with idiopath...2023-12-0627 minJHLT: The PodcastJHLT: The PodcastEpisode 36: November 2023It’s pulmonary hypertension month on JHLT: The Podcast! The JHLT Digital Media Editors explore two PVD-related manuscripts from the November issue of The Journal of Heart and Lung Transplantation. Digital Media Editor Marty Tam, MD, assistant professor in the division of cardiovascular medicine at the University of Michigan, hosts this episode.   First, hear from first author Zvonimir Rako, MD, on his team’s study “Clinical and functional relevance of right ventricular contraction patterns in pulmonary hypertension.”   The right ventricle (RV) has a complex contraction pattern. For patients with pulmonary hypertension (PH), right...2023-11-0119 minJHLT: The PodcastJHLT: The PodcastEpisode 35: October 2023The JHLT Digital Media Editors explore two manuscripts from the October issue of The Journal of Heart and Lung Transplantation—the first on lung transplantation in patients with stacked risks, and the second on bacterial pathogens found at driveline exit sites in patients with ventricular assist devices. Digital Media Editor Marty Tam, MD, assistant professor in the division of cardiovascular medicine at the University of Michigan, hosts this episode.   First, hear from senior author Edward Cantu, MD, MSCE, on his team’s study “Transplanting candidates with stacked risks negatively affects outcomes.”   Lung trans...2023-10-0420 minJHLT: The PodcastJHLT: The PodcastEpisode 34: September 2023In this special issue of JHLT: The Podcast, the JHLT Digital Media Editors explore just one study—and devote the second half of the episode as a tribute to recently retired Editor-in-Chief, Dr. Daniel R. Goldstein. Digital Media Editor Van-Khue Ton, MD, heart failure and transplant cardiologist at Massachusetts General Hospital, hosts this episode.   First, hear from senior author William F. Parker, MD, MS, PhD, on his team’s study “Association of high-priority exceptions with waitlist mortality among heart transplant candidates.” Dr. Parker is a pulmonary and critical care physician, health services researcher, and clinical medical e...2023-09-0625 minJHLT: The PodcastJHLT: The PodcastEpisode 33: August 2023The JHLT Digital Media Editors explore two manuscripts from the August issue of The Journal of Heart and Lung Transplantation—the first on immunosuppression in pediatric heart transplantation, and the second TA-NRP in DCD lung transplantation. Digital Media Editor Van-Khue Ton, MD, heart failure and transplant cardiologist at Massachusetts General Hospital, hosts this episode.   First, hear from senior author Steven C. Greenway, MSc, MD, on his team’s study “Single-drug immunosuppression is associated with noninferior medium-term survival in pediatric heart transplant recipients.” Dr. Greenway shares his journey from enzyme biochemistry in mollusks, snails, and frogs to pediat...2023-08-0220 minJHLT: The PodcastJHLT: The PodcastEpisode 32: July 2023The JHLT Digital Media Editors explore two manuscripts from the July issue of The Journal of Heart and Lung Transplantation—one on heart transplantation and one on lung transplantation. Digital Media Editor Marty C. Tam, MD, Assistant Professor at the University of Michigan, hosts this episode.   First, hear from co-first author Kevin Chen, MD, on his team’s study “Donation after circulatory death heart procurement strategy impacts utilization and outcomes of concurrently procured abdominal organs,” which comes from Cedars-Sinai. The study looks into the results of DCD organ donation depending on the technique used at procureme...2023-07-0532 minJHLT: The PodcastJHLT: The PodcastEpisode 31: June 2023On the June episode of JHLT: The Podcast, the Digital Media Editors explore two manuscripts from the June issue of The Journal of Heart and Lung Transplantation, with authors from the US and Denmark.   First, hear from senior author Steven R. Hays, MD, on his team’s study “Design and implementation of a digital health home spirometry intervention for remote monitoring of lung transplant function,” which explores digital health and comes out of UCSF. In the study, the authors developed an automated digital health intervention using Bluetooth-enabled home spirometers to monitor for complications after lung transpl...2023-06-0722 minJHLT: The PodcastJHLT: The PodcastEpisode 30: May 2023On May’s JHLT: The Podcast, we feature two manuscripts from the May issue of The Journal of Heart and Lung Transplantation.   First, the editors explore a study entitled “Donor hyperoxia is a novel risk factor for severe cardiac primary graft dysfyunction,” which comes from Kransdorf and colleagues at Cedars Sinai Medical Center in Los Angeles.   The editors welcome first author Evan Kransdorf, MD, PhD, to share how he transitioned from oncology to heart failure and transplantation, and to talk about the findings of the study. The Digital Media Editors want to know...2023-05-0323 minJHLT: The PodcastJHLT: The PodcastEl podcast de JHLT en Español: Abril 2023 El podcast de JHLTenEspañol: presentamos por primera vez un podcast de JHLT en Español, conducido por Marta Farrero, MD, PhD, en el que repasamos 4 artículos destacados de 2022, cada uno centrado en el foco de interés de las redes interdisciplinarias de ISHLT. El artículo sobre soporte circulatorio se titula “La recuperación de la función ventricular se asocia con mejores resultados en asistencia ventricular”, con Cameron Olsen, MD, como primer firmante, y es comentado por el Sebastián Rojas, MD. Se analiza el impacto clínico favorable de la recuperación de la fracción de...2023-04-1223 minDozeCast - CardiologiaDozeCast - Cardiologia078 - Cateterismo Direito na Insuficiência Cardíaca Avançada⁠DozeNews PRIME⁠: as melhores e mais didáticas revisões de cardiologia direto na sua caixa de entrada! Assine agora e tenha acesso à todo material já produzido! - ⁠https://dozeporoito.substack.com/ No episódio de hoje, colocamos o cateterismo direito em foco, e trazemos a discussão sobre as indicações e principalmente a interpretação do exame sob duas óticas complementares; Marcos Meniconi e sua rica experiência do laboratório de hemodinâmica realizando os exames, acompanhado de Victor Bemfica e Rapha Rossi trazendo sua experiencia na condução e acompanhamento dos pacientes portador...2023-04-0644 minJHLT: The PodcastJHLT: The PodcastEpisode 28: April 2023It’s another COVID-19 special on this month’s JHLT: The Podcast, which features two articles on COVID-19 and thoracic organ transplantation from the April issue of The Journal of Heart and Lung Transplantation.   First, the editors explore a study entitled “Heart transplantation for COVID-19 myopathy in the United States,” which comes from Gill and colleagues at Cedars Sinai Medical Center in Los Angeles.   The editors welcome first author George Gill, MD, to share what brought him from the United Kingdom to the States, and to talk about the findings of the study...2023-04-0532 minJHLT: The PodcastJHLT: The PodcastEpisode 27: March 2023This month’s JHLT: The Podcast is hosted by Digital Media Editor David Schibilsky, MD, who leads a discussion of two studies from the March issue of The Journal of Heart and Lung Transplantation—and the first authors who presented them.   First, the editors explore a study entitled “Angiopoietin 2 and hsCRP are associated with pulmonary hemodynamics and long-term mortality respectively in CTEPH—Results from a prospective discovery and validation biomarker study,” which comes from Hadinnapola and colleagues at the Papworth group in Cambridge, UK.   The editors welcome Charaka Hadinnapola, MA, MB, BChir, first...2023-03-0120 minJHLT: The PodcastJHLT: The PodcastEpisode 26: February 2023This month on JHLT: The Podcast, the JHLT Digital Media Editors review two studies from the February issue of The Journal of Heart and Lung Transplantation—and bring in a couple of experts to help them make sense of some new technology.   First, the editors explore a pre-clinical study entitled “The dynamic cellular landscape of grafts with acute rejection after heart transplantation,” which comes from Kong and colleagues at Zhejiang University in Hangzhou, China.   Single cell technologies are emerging as non-biased techniques to discover novel biological pathways in a variety of pre-clin...2023-02-0137 minJHLT: The PodcastJHLT: The PodcastEpisode 25: January 2023JHLT: The Podcast kicks off 2023 with a look back at 2022. Daniel R. Goldstein, MD, Editor-in-Chief of JHLT, joins the JHLT Digital Media Editors for a recap of the past year of The Journal of Heart and Lung Transplantation.   Studies include: Pérez-Carrillo, et al, “Diagnostic value of serum miR-144-3p for the detection of acute cellular rejection in heart transplant patients.” Feb 2022 JHLT Han, et al, “Impact of using higher-risk donor hearts for candidates with pre-transplant mechanical circulatory support.” Feb 2022 JHLT Jackson, et al, “Heart transplant outcomes in cardiac sarcoidosis.” Jan 2022 JHLT Ribeiro, et al, “Ex viv...2023-01-0422 minJHLT: The PodcastJHLT: The PodcastEpisode 24: December 2022This month on JHLT The Podcast, JHLT Digital Media Editor Marty Tam, MD, takes over hosting duties to present two papers from the December issue of The Journal of Heart and Lung Transplantation. Listen now to hear study authors discuss their work, their studies, and next steps for their research. First, we welcome first author Jorge V. López-Ibor, MD, and senior author Javier Segovia-Cubero, MD, PhD, about their team’s study from Hospital Universitario Puerto de Hierro Majadahonda entitled “Role of TGF-β1 +869T>C polymorphism in renal dysfunction one year after heart transplantation.” Drs. López-Ibor and Segov...2022-12-0727 minJHLT: The PodcastJHLT: The PodcastEpisode 23: November 2022This month on JHLT The Podcast, JHLT Digital Media Editor Van-Khue Ton, MD, takes over hosting duties to present two unique papers from the November issue of The Journal of Heart and Lung Transplantation. Listen now to hear study authors discuss their work, their studies, and next steps for their research. First, we welcome first author Megan M. Collins, MD, about her team’s study from the University of Utah entitled “Attitudes & practices surrounding pregnancy post heart transplantation among pediatric providers.” Dr. Collins shares her journey from being an undergraduate economics major to her current career in pediat...2022-11-0225 minJHLT: The PodcastJHLT: The PodcastEpisode 22: October 2022For this month’s episode, JHLT The Podcast explores two impactful studies from the October issue of The Journal of Heart and Lung Transplantation. The episode is hosted by Daniel R. Goldstein, MD, Editor-in-Chief of JHLT, who is joined by the JHLT Digital Media Editors. Listen now to hear study authors discuss their work, their studies, and next steps for their research. First, the editors speak with first author Michael Harhay, PhD (pictured left) and senior author Edward Cantu, MD (pictured right), about their study from the University of Pennsylvania entitled “Epidemiology, risk factors and outcomes of lung...2022-10-0533 minThe Pharm So Hard Podcast: An Emergency Medicine and Hospital Pharmacy PodcastThe Pharm So Hard Podcast: An Emergency Medicine and Hospital Pharmacy PodcastEpisode 84. LVAD Emergencies with Raphaelle Lombardo, PharmD, BCPSLVAD emergencies expert consensus ISHLT LVAD guidelines Transcript The post Episode 84. LVAD Emergencies with Raphaelle Lombardo, PharmD, BCPS appeared first on The Pharm So Hard Podcast.2022-09-1358 minJHLT: The PodcastJHLT: The PodcastEpisode 21: September 2022This month—two studies on COVID-19! Daniel R. Goldstein, MD, Editor-in-Chief of JHLT, is taking a short break, so the episode is hosted by Digital Media Editor Erika Lease, MD. Both COVID-19 studies come from the September issue of The Journal of Heart and Lung Transplantation, and in the episode, you’ll learn more about each study and their authors.   First, the editors speak with Yael Peled, MD, Medical Director of the Heart Transplant Service at the Sheba Medical Center in Ramat Gan, Israel. She’s the first author on a paper entitled “Fourth BNT162b2 vaccin...2022-09-0722 minJHLT: The PodcastJHLT: The PodcastJHLT: The Podcast Episode 20: August 2022This month, Daniel R. Goldstein, MD, Editor-in-Chief of JHLT, and the JHLT Digital Media Editors are discussing two impactful studies—in pediatric heart transplantation and MCS—from the August issue of The Journal of Heart and Lung Transplantation. You’ll hear more about each of these studies, as well as the authors themselves. First, the editors speak with Craig Laurence, MD (pictured), a consultant in Pediatric Cardiology and Heart Failure & Transplantation at Great Ormond Street Hospital in London, UK. He’s the first author on a paper entitled “Pediatric heart transplantation following donation after circulatory death, distant procuremen...2022-08-0326 minJHLT: The PodcastJHLT: The PodcastJHLT: The Podcast Episode 19: July 2022This month, Daniel R. Goldstein, MD, Editor-in-Chief of JHLT, and the JHLT Digital Media Editors are discussing two studies from the July issue of The Journal of Heart and Lung Transplantation, one from the LVAD domain and the other from the field of lung transplantation. You’ll hear more about each of these studies, as well as the authors themselves. First, the editors speak with Paulino Alvarez, MD, from the Cleveland Clinic, about his paper entitled “Outcomes of bariatric surgery in patients with left ventricular assist devices.” Dr. Goldstein, Marty Tam, MD, and Van-Khue Ton, MD, interview Dr. Al...2022-07-0634 minJHLT: The PodcastJHLT: The PodcastJHLT: The Podcast Episode 18: June 2022Join Daniel R. Goldstein, MD, Editor-in-Chief of JHLT, and the JHLT Digital Media Editors for two interviews with groups of authors from the June issue of The Journal of Heart and Lung Transplantation. You’ll hear more about each of these teams as well as more about the work they’re publishing this month. First, the editors speak with senior author Evgenij V. Potapov, MD (left) and first author Jaime-Jürgen Eulert-Grehn, MD (right), both of the German Heart Center, about their paper entitled “Defibrillator generator replacements in patients with left ventricular assist device support: The risks of hema...2022-06-0140 minJHLT: The PodcastJHLT: The PodcastJHLT: The Podcast Episode 17: May 2022Join Daniel R. Goldstein, MD, Editor-in-Chief of JHLT, and the JHLT Digital Media Editors for two interviews with authors from the May issue of The Journal of Heart and Lung Transplantation. You’ll hear about the scientific journey of each of these authors as well as more about the work they’re publishing this month. First, the editors speak with John Greenland, MD, PhD (pictured), from the University of California San Francisco, who is the first author of a paper entitled “Lung transplant recipients with idiopathic pulmonary fibrosis have impaired alloreactive immune responses.” Erika Lease, MD, interviews Dr. Gree...2022-05-0422 minJHLT: The PodcastJHLT: The PodcastJHLT: The Podcast Episode 16: April 2022Join Daniel R. Goldstein, MD, Editor-in-Chief of JHLT, and the JHLT Digital Media Editors for two interviews with first authors from the April issue of The Journal of Heart and Lung Transplantation. Both studies relate to viruses in thoracic organ transplantation—but not coronaviruses! Josue Villegas-Galaviz, MD (pictured), from the University of Kentucky, who is the first author of a paper entitled “Clinical outcomes of heart transplantation using hepatitis c-viremic donors.” Marty Tam, MD, and David Schibilsky, MD, interview Dr. Villegas-Galaviz about his multi-country journey to become a clinical and research fellow. They also explore the findings of his...2022-04-0623 minJHLT: The PodcastJHLT: The PodcastJHLT: The Podcast Episode 15: March 2022Join Daniel R. Goldstein, MD, Editor-in-Chief of JHLT, and the JHLT Digital Media Editors for two interviews with first and senior authors from two studies in the March issue of The Journal of Heart and Lung Transplantation. They’re also joined by JHLT Social Media Editor Aman Sidhu, MSc, MD, to help host the show. First, the editors speak with both the first and last authors of a paper entitled “Post-transplantation outcomes of sensitized patients receiving durable mechanical circulatory support.”  Jong-Chan Youn, MD, PhD, is the first author on the paper, and Jon A. Kobashigawa, MD, former ISHLT p...2022-03-0230 minJHLT: The PodcastJHLT: The PodcastFebruary 2022Join Daniel R. Goldstein, MD, Editor-in-Chief of JHLT, and the JHLT Digital Media Editors for two interviews with authors from the February issue of The Journal of Heart and Lung Transplantation. First, the editors speak with Georg Hansmann, MD, PhD, Associate Professor of Pediatrics at Hannover Medical School. Dr. Hansmann is the lead author on a paper entitled “Full recovery of right ventricular systolic function in children undergoing bilateral lung transplantation for severe PAH.” Beginning at 1:37, Erika Lease, MD, interviews Dr. Hansmann about the findings of the study, follow up recommendations, and potential practice changes in clinical sett...2022-02-0230 minJHLT: The PodcastJHLT: The PodcastJanuary 2022JHLT: The Podcast kicks off 2022 with a look back at 2021! Daniel R. Goldstein, MD, Editor-in-Chief of JHLT, joins the JHLT Digital Media Editors for a recap of the past year of The Journal of Heart and Lung Transplantation. Studies include: Macdonald, et al, “The impact of frailty on mortality after heart transplantation,” Feb 2021 JHLT Glinton, et al, “Bone marrow-derived AXL tyrosine kinase promotes mitogenic crosstalk and cardiac allograft vasculopathy,” June 2021 JHLT Jang, et al, “Donor-derived cell-free DNA accurately detects acute rejection in lung transplant patients, a multicenter cohort study,” Aug 2021 JHLT Scheuer, et al, “Heart transplantation following dona...2022-01-0519 minJHLT: The PodcastJHLT: The PodcastDecember 2021It’s time for the final episode of JHLT: The Podcast for 2021! Join Daniel R. Goldstein, MD, Editor-in-Chief of JHLT, and the JHLT Digital Media Editors for two interviews with authors from the December issue of The Journal of Heart and Lung Transplantation. Both studies focus on protein biomarkers in thoracic transplantation. First, the editors speak with Tereza Martinu, MD, MHS, Assistant Professor and Clinician at Toronto General Hospital. Dr. Martinu is the lead author on a paper entitled “Bronchoalveolar lavage cytokine-based risk stratification of minimal acute rejection in clinically stable lung transplant recipients.” Beginning at 1:45, Erika Lease...2021-12-0126 minJHLT: The PodcastJHLT: The PodcastNovember 2021JHLT: The Podcast is back with an all-pediatric episode for November! Join Daniel R. Goldstein, MD, Editor-in-Chief of JHLT, and the JHLT Digital Media Editors for TWO interviews with authors from the November issue of The Journal of Heart and Lung Transplantation. First, the editors speak with Dr. Richard Issitt, FCCP, from the perfusion department at Great Ormond Steret Hospital in London. Dr. Issitt is the lead author on a paper entitled “Intraoperative anti-A/B immunoadsorption is associated with significantly reduced blood product utilization with similar outcomes in pediatric ABO-incompatible heart transplantation.” Beginning at 2:05, Erika Lease, MD, inte...2021-11-0326 minJHLT: The PodcastJHLT: The PodcastOctober 2021It’s October on JHLT: The Podcast! Join Daniel R. Goldstein, MD, Editor-in-Chief of JHLT, for a discussion with the JHLT Digital Media Editors about two studies in the October issue of The Journal of Heart and Lung Transplantation. First, the editors have the pleasure of interviewing Stephen Hoole, MA, BM, BCh, DM, FRCP, FESC, FACC, Consultant Interventional Cardiologist at Royal Papworth Hospital and Honorary Senior Visiting Fellow at the University of Cambridge. Dr. Hoole is a the senior author on a paper entitled “Serial right heart catheter assessment between balloon pulmonary angioplasty sessions identify procedural factors that...2021-10-0621 minJHLT: The PodcastJHLT: The PodcastSeptember 2021In the September 2021 episode of JHLT: The Podcast, Daniel R. Goldstein, MD, Editor-in-Chief of JHLT, leads a discussion with the JHLT Digital Media Editors about two studies in the September issue of The Journal of Heart and Lung Transplantation. Starting at 1:26, David Schibilsky, MD, Marty Tam, MD, and Van-Khue Ton, MD, PhD, discuss a paper from Benck and colleagues at Cedars-Sinai entitled “Recipient and surgical factors trigger severe primary graft dysfunction after heart transplant.” Starting at 12:27, Dr. Goldstein and Erika Lease, MD, discuss a study from Urso et al from Columbia University, called “Aspiration of conjug...2021-09-0120 minJHLT: The PodcastJHLT: The PodcastBONUS: August 2021On this BONUS episode of JHLT: The Podcast, JHLT Editor-in-Chief Daniel R. Goldstein, MD, returns for an additional brief conversation with Saima Aslam, MD, MS, chair of the ISHLT COVID-19 Task Force. Dr. Aslam provides some key updates about vaccination for SARS-CoV-2 in organ transplant recipients, including updated efficacy information, recommendations about booster doses, and breakthrough infections. Learn more about the work of the ISHLT COVID-19 Task Force, and get the latest publications and recommendations documents, at ishlt.org/covid-19-information. Don’t already get the Journal and want to read along? Join the International Society of He...2021-08-1909 minJHLT: The PodcastJHLT: The PodcastAugust 2021Welcome to the August 2021 episode of JHLT: The Podcast. In this special episode, Daniel R. Goldstein, MD, Editor-in-Chief of JHLT, and the JHLT Digital Media Editors, interview ISHLT COVID-19 Task Force Chair Saima Aslam, MD, MS, about the latest, critical information on SARS-CoV-2 vaccinations in immunosuppressed thoracic organ transplant recipients. The August issue of JHLT contains two key studies exploring COVID-19 vaccinations—one from Peled et al examining the safety and efficacy of the BNT162b2 mRNA vaccine in heart transplant recipients, and another from Havlin et al exploring lung transplantation. In addition to summarizing an...2021-08-0427 minJHLT: The PodcastJHLT: The PodcastJuly 2021Welcome to the July 2021 episode of JHLT: The Podcast! Daniel R. Goldstein, MD, Editor-in-Chief of JHLT, leads a discussion with the JHLT Digital Media Editors about two studies in the July issue of The Journal of Heart and Lung Transplantation. Starting at 1:45, Dr. Goldstein and Erika Lease, MD, discuss a paper from Sage, et al, at the University of Toronto, Canada, titled “Prediction of donor related lung injury in clinical lung transplantation using a validated ex vivo lung perfusion inflammation score.” Starting at 10:45, Van-Khue Ton, MD, PhD, and Marty Tam, MD, discuss a study from Rafe...2021-07-0717 minJHLT: The PodcastJHLT: The PodcastJune 2021The June episode of JHLT: The Podcast is now live, and features a first for the podcast—an interview with a JHLT author! In this episode, host Daniel R. Goldstein, MD, Editor-in-Chief of the Journal of Heart and Lung Transplantation, conducts an interview of Kiran Khush, MD, MAS, member of the ISHLT Board of Directors and Professor of Medicine and Director of Heart Transplant Research at Stanford University. In the episode, Dr. Khush is interviewed by JHLT Digital Media Editors Erika Lease, MD, David Schibilsky, MD, and Van-Khue Ton, MD, PhD, on her state of the art re...2021-06-0220 minJHLT: The PodcastJHLT: The PodcastMay 2021JHLT: The Podcast is back with round table talks for the May 2021 issue of the Journal of Heart Transplantation. Daniel R. Goldstein, MD, Editor-in-Chief of JHLT, leads a discussion with the JHLT Digital Media Editors. Starting at 1:36, Van-Khue Ton, MD, PhD, and Martin Tam, MD, discuss an paper from Dr. Englung and colleagues in Oslo, Norway, titled “Intravenous iron supplement for iron deficiency in cardiac transplant recipients (IronIC): A randomized clinical trial.” Starting at 9:04, Erika Lease, MD, and David Schibilsky, MD, discuss a study from Fessler et al in Paris, France, called “Operating room extubation: A pred...2021-05-0518 minJHLT: The PodcastJHLT: The PodcastApril 2021Welcome back to JHLT: The Podcast and our round table talks. Daniel R. Goldstein, MD, Editor-in-Chief of the Journal of Heart and Lung Transplantation, leads a discussion with the JHLT Digital Media Editors focusing on topics from the April issue of JHLT. In this episode, we are happy to welcome our first-ever guest, David Peng, MD, Director of Pediatric Heart Failure and Mechanical Circulatory Support at the University of Michigan. Starting at 1:45, Van-Khue Ton, MD, PhD, and Marty Tam, MD, are in discussion with David on a timely paper by Dr. Danielle Sganga and colleagues, titled “Comparison of...2021-04-0720 minJHLT: The PodcastJHLT: The PodcastMarch 2021JHLT: The Podcast is back for its third round table talks. Daniel R. Goldstein, MD, Editor-in-Chief of the Journal of Heart and Lung Transplantation, leads a discussion with the JHLT Digital Media Editors focusing on topics from the March issue of JHLT. Starting at 2:05, David Schibilsky, MD, and Van-Khue Ton, MD, PhD, discuss an MCS paper from Dr. McGiffin and colleagues in Melbourne, Australia, titled “The results of a single-center experience with HeartMate 3 in a biventricular configuration.” Starting at 14:00, Erika Lease, MD, and Marty Tam, MD, discuss a study from Benke and colleagues in Budapest, Hung...2021-03-0327 minJHLT: The PodcastJHLT: The PodcastFebruary 2021Welcome back to JHLT: The Podcast! Daniel R. Goldstein, MD, Editor-in-Chief of the Journal of Heart and Lung Transplantation, holds a round table discussion with the JHLT Digital Media Editors focusing on topics from the February issue of JHLT. In this episode, Erika Lease, MD, discusses a study from Marklin and colleagues in St. Louis, MO USA that explores ventilation in the prone position and how it impacts transplantation from lung donors with hypoxemia and atelectasis. David Schibilsky, MD; Marty Tam, MD; and Van-Khue Ton, MD, PhD, discuss a study led by Gonzalez and colleagues...2021-02-0326 minJHLT: The PodcastJHLT: The PodcastJanuary 2021On the inaugural episode of JHLT: The Podcast, join Daniel R. Goldstein, MD, Editor-in-Chief of the Journal of Heart and Lung Transplantation, in a round table discussion with the JHLT Digital Media Editors. This companion piece to the January issue of JHLT will give quick insights into some of the most compelling and fascinating studies in transplantation and advanced heart and lung failure from the Journal.   In this episode, Erika Lease, MD, discusses donor ventilation parameters and lung transplantation; while Marty Tam, MD, and Van-Khue Ton, MD, PhD, discuss thrombosis events and LVADs. Follow along i...2021-01-0622 minCardionerds: A Cardiology PodcastCardionerds: A Cardiology Podcast69. Case Report: Cardiac Allograft Vasculopathy (CAV) – UCSDCardioNerds (Amit Goyal & Daniel Ambinder) join University of California San Diego (UCSD) cardiology fellows (Harpreet Bhatia, Dan Mangels, and Quan Bui) for a relaxing beach bonfire in the beautiful city of San Diego! They discuss a challenging case of post-transplant cardiac allograft vasculopathy. Dr. Hao (Howie) Tran provides the E-CPR and program director Dr. Daniel Blanchard provides a message for applicants. Episode notes were developed by Johns Hopkins internal medicine resident Richard Ferraro with mentorship from University of Maryland cardiology fellow Karan Desai.   Jump to: Patient summary - Case media - Case teaching - References The CardioNerds Cardiology Case Reports series shines l...2020-10-131h 39Neuro ResusNeuro ResusVAD & transplanted patient with non-cardiac critical illnessUse of Ventricular Assist Devices (VAD) and heart transplantation (HT) for end stage cardiac failure have increased significantly in recent decades. These support strategies hold inherently different risks in the face on non-cardiac critical illness, and require multidisciplinary team management.   According to INTERMACS, more than 2500 VADs/year are implanted the USA. Most implanted devices are continuous flow left-VADs (75%) which deliver systemic cardiac output directly related to pump speed and inversely related to pressure gradient across the pump. Improved survivorship has resulted in increasing outpatient management, however 12-month mortality is 12%, and 1/4 of patients within 1-year post-transplant. Systemic illnesses may a...2018-09-1918 minMedizin - Open Access LMU - Teil 21/22Medizin - Open Access LMU - Teil 21/22Ten-Year Results of a Randomized Trial Comparing Tacrolimus Versus Cyclosporine A in Combination With Mycophenolate Mofetil After Heart TransplantationBackground. Long-term results of prospective randomized trials comparing triple immunosuppressive strategies combining tacrolimus (TAC) or cyclosporine A (CsA) with mycophenolate mofetil (MMF) and steroids after heart transplantation (HTX) are rarely published. Therefore, we collected long-term follow-up data of an intervention cohort 10 years after randomization. Methods. Ten-year follow-up data of 60 patients included in a prospective, randomized trial between 1998 and 2000 were analyzed as intention-to-treat (TAC-MMF n=30; CsA-MMF n=30). Baseline characteristics were well balanced. Cardiac allograft vasculopathy (CAV) was graduated in accordance with the new ISHLT classification. Results. Survival at 1, 5, and 10 years was 96.7%, 80.0%, and 66.7% for TAC-MMF and 90.0%, 83.3%, and 80.0% for CsA-MMF (P=ns). Freedom...2013-02-0100 min