Shows
TD Cowen InsightsHarnessing Genomics, With PacBio's Christian HenryThrough conversations with leading innovators and executives across the industry, TD Cowen's ToolTalks podcast series seeks to explore the key technologies and business strategies that are transforming life science and clinical diagnostics markets today. Each episode aims to highlight the potential for Tools to enable more efficacious drugs, lower care costs, and provide better and earlier diagnoses that ultimately extend and save human lives. In the podcast's inaugural episode, TD Cowen's health care analyst Dan Brennan hosts Christian Henry, Pacific Biosciences President and CEO, to understand the progress and continued promise of next-generation sequencing to deliver new biological insights...2025-07-2528 min
Explain PodcastE15: Singular Genomics | ATAC-seqSharing a flowcell, reinventedChapters:- 00:00 usegalaxy.org- 07:55 Singular Genomics start- 21:55 Max Reads- 29:40 DNA Structure / ATAC-seqSetup galaxy on local hardware: https://galaxyproject.org/admin/get-galaxy/G4 is competing with Illumina:https://www.genengnews.com/topics/omics/fast-and-flexible-singulars-g4-takes-aim-at-illuminas-sequencing-superiority/Singulars chemistry is one of many:https://www.nature.com/articles/d41586-023-00512-4How max reads...2025-05-2846 min
Explain PodcastE13: Sequencing by Avidity | Element Biosciences + XLEAPBecause sometimes a jellyfish prevents quenchingChapters:01:00 - XLeap update from Illumina08:00 - Avidites start, splitting the problems13:20 - In-depth comparison to Illumina22:00 - Element summary23:30 - Bioinformatics tools: Jellyfish, KAT25:00 - QuickGen: GWASIllumina about their XLeap: https://www.illumina.com/science/genomics-research/articles/data-quality-q-scores.htmlSandiegomics about element: https://sandiegomics.com/element-beats-illumina-to-the-200-genome/Nature paper about the chemistry: https://www.nature.com/articles/s41587-023...2025-03-1239 min
Productivity MasteryBuilding a Unicorn from Scratch: The Journey of Element Biosciences | PM #204 with Molly He🚀 In episode #204 we welcomed Molly He, co-founder and CEO of Element Biosciences.Subscribe to Productivity Mastery Podcast on your favorite platform 👇Spotify: https://open.spotify.com/show/3DHrGKvqCduaXrEHrHazAR?si=92e8b757ef55433bApple Podcasts: https://podcasts.apple.com/us/podcast/productivity-mastery/id1514614289Google Podcasts: https://podcasts.google.com/feed/aHR0cHM6Ly9hbmNob3IuZm0vcy8yMGVmMmZmYy9wb2RjYXN0L3Jzcw==Listen to this episode and learn:💡The inspiring story of Molly He, born and raised in a poor area in ChinaEntrepreneurial lessons from raising 680M and building a team of 400+ people💡W...2025-01-281h 02
Illumina Genomics PodcastThe Genomic Revolution Transforming Public Health in Africa with Next-Generation Sequencing (NGS) with Professor Martin NyagaIn this episode of the Illumina Genomics Podcast Illumina’s Amadou Gueye, Marketing Lead for the Middle East & Africa speaks to Professor Martin Nyaga, Head of the Next Generation Sequencing (NGS) Unit at the School of Biomedical Sciences at the University of the Free State. This interview takes a close look at how NGS is revolutionizing public health in Africa and how genomics has been a game-changer in identifying, tackling and tracking associated disease outbreaks. Hear as Professor Nyaga explains the impact of infectious diseases in Africa and how his establishment of the NGS Unit at the University of the Fr...2025-01-2332 min
The Root Cause Medicine PodcastHow Oral Bacteria Impact Your Health with Brian MaurerIn today's episode of The Root Cause Medicine Podcast, Brian Maurer, Co-Founder of Bristle Health, joins Dr. Kate Kresge to dive into the Rupa Health and Bristle Health partnership to change the game in oral microbiome testing. You’ll hear us discuss:How Bristle Health is transforming oral microbiome testingHow oral bacteria impact your whole bodyWhy brushing and flossing isn't enough to beat cavitiesThe link between oral health and autoimmune diseasesOver seven years, Brian played a key role in driving the adoption of genomics at...2024-12-1049 min
The Rose WomanYou as a Data Stream: The New World of Multiomics and Optimizing Healthspan with Dr. Michael SnyderWelcome to the Rose Woman Podcast, where we explore the cutting edge of health, wellness, and personal empowerment. Today, we have a very special guest - Dr. Michael Snyder, a leader in the field of functional genomics and proteomics, and one of the major participants of the ENCODE project.He has also combined different state-of-the-art "omics" technologies to perform the first longitudinal detailed integrative personal omics profile (iPOP) of person and used this to assess disease risk and monitor disease states for personalized medicine. Dr. Snyder is the cofounder of Personalis, SensOmics, Qbio @qbioinc, January AI, Filtricine...2024-11-1649 min
The FocusCore PodcastPushing the Boundaries of Biotechnology with Arjuna Kumarasuriyar from IlluminaThe latest Focus Core Salary Guide is here: 2025 Salary Guide Welcome to the latest episode of the FocusCore podcast. In this episode we are talking about the field of Genomics and how the applied genomics technology company, Illumina is pushing the boundaries of genomic biotechnology for research and in applied medicine. Our guest is General Manager and Representative Director of Illumina KK, Arjuna Kumarasuriyar. Arjuna has commercial experience in sales, marketing, channel management and commercial operations, as well as an academic background in biotechnology and molecular biology. In the episode we dive deep into what genomics is...2024-11-1450 min
硅谷101E171｜濒临破产的23andMe与基因检测行业的新旧交替基因检测曾被视为未来医疗的新蓝海。当23andMe还是资本趋之若鹜的独角兽时，人们兴高采烈地交出自己的唾沫，相信它将引领下一个科技革命。但如今，这家公司不仅市值仅剩巅峰时期的2%，更面临退市风险；另一家明星公司uBiome的两位创始人更因诈骗可能面临千年刑期。
这真的是基因检测的终局吗？就在23andMe陨落之际，一批专注垂直领域的新公司正在悄然崛起。据预测，消费级基因检测市场将从2023年的19亿美元增长到2030年的88亿美元。本期节目我们邀请到N1 Life联合创始人与CEO Janice 臧晓羽博士，聊聊基因检测行业的新旧更替，以及为何这个行业骗局层出不穷。
本期节目为硅谷101和Airdrop从天而降的串台节目。
【主播】
泓君Jane，硅谷101创始人，播客主理人
【嘉宾】
Janice Zang臧晓羽博士，N1 Life联合创始人兼CEO，Airdrop从天而降主播
【你将听到】
02:35 23andMe：靠互联网思维把基因检测的价格打了下来
06:21 Ancestry：对自己祖先的好奇心大过于医疗需求
08:00 平摊“开机费”：批量测序可以降低单位成本
13:25 性感的故事，高昂的成本，平庸的产品：23andME从未盈利
16:39 成也数据，败也数据
27:54 新一代基因检测公司正在从全面检测转向专精细分
33:32 基因检测的新模式：订阅制、个性化、加入增值服务
36:51 APOE与阿兹海默症：完全通过基因靶点来诊断疾病还为时尚早
41:59 HER2基因：基因检测目前只能应用在有限的领域
44:01 第二个Theranos：uBiome的新型骗局
56:36 CRISPR对科学的影响不亚于生成式AI
58:52 CAS蛋白和Guide RNA：给编辑基因的剪刀装上了眼睛
01:01:16 基因治疗的挑战在于准确递送基因编辑器和药物
【其他相关信息】
Ancestry：全球最大的家谱研究和DNA检测服务公司之一，成立于1983年，拥有数十亿份历史档案记录，其核心业务包括在线家谱研究、DNA检测服务和家谱树制作工具。
illumina：专注于开发和销售基因测序仪器及试剂的生物技术公司。成立于1998年，总部位于美国加州，Illumina的产品主要面向科研机构、医院和制药公司，用于基因组学研究和临床应用。NGS（下一代测序）技术是Illumina的核心业务之一，这项技术能够高通量地测序DNA和RNA序列，显著加快基因组学研究的速度，降低成本。NGS被广泛应用于癌症研究、遗传病筛查和微生物组分析等领域。
SelfDecode：一家提供基因检测和个性化健康建议的公司，它结合基因数据和人工智能算法，帮助用户分析DNA，生成健康报告，并提供饮食、营养和生活方式的建议。
InsideTracker：结合血液检测、DNA分析和生活方式数据，为用户提供个性化的健康建议和优化方案的健康分析公司。它的服务包括追踪生物标志物（如维生素水平、炎症指标等），并根据结果提出饮食、锻炼和补充剂的推荐。
10x Genomics：一家生物技术公司，成立于2012年，总部位于美国加州。公司专注于单细胞基因组学、转录组学和空间基因组学的技术开发，主要产品包括单细胞分析和空间基因组测序仪器及试剂。这些工具用于帮助科研人员在单细胞层面分析基因表达、细胞特性和空间分布，广泛应用于癌症研究、免疫学和神经科学等领域。10x Genomics的客户主要是研究机构和生物制药公司，用于推动疾病研究和新疗法开发。
Roche（罗氏）：一家总部位于瑞士的跨国医疗健康公司，成立于1896年，主要专注于制药和诊断领域，提供创新的药物和诊断技术，用于癌症、免疫系统疾病、传染病和中枢神经系统疾病的治疗和检测。
uBiome：一家成立于2012年的微生物基因组学公司，曾专注于分析人体微生物群，提供健康报告。公司最初通过直接面向消费者的检测产品获得市场认可，但为了扩大规模，逐步转向依赖保险报销模式。uBiome被指控多次向保险公司提交未经医生批准的检测费用报销，还涉嫌诱导医生开具不必要的测试，以增加收入。此外，公司被控夸大技术能力和市场需求，误导投资者。2019年，FBI突击搜查了uBiome的总部，公司随即遭到多项诉讼并在同年申请破产。
LabCorp：Laboratory Corporation of America，是一家美国医疗检测公司，总部位于北卡罗来纳州。它为医院、医生和患者提供广泛的实验室检测服务，包括血液检测、病理学、基因组学和毒理学检测。
Quest Diagnostics：美国最大的医学实验室检测公司之一，与LabCorp业务类似。主营常规医学检测、基因检测和健康信息服务，在新冠期间同样是主要检测服务商。
APOE：Apolipoprotein E，载脂蛋白E，参与脂质代谢，是控制血液中胆固醇和甘油三酯水平的重要因素。
HER2：一种膜受体酪氨酸激酶，也称为人表皮生长因子受体2。HER2是乳腺癌等多种癌症的重要靶点。
【监制】
杜秀
【后期】
AMEI
【BGM】
One Last Drama - Philip Ayers
Devils On The Doorstep 1 - Fredrik Ekstrom
The Road to Odessa - Lama House
【在这里找到我们】
公众号：硅谷101
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联系我们：podcast@sv101.netSpecial Guest: 臧晓羽.2024-11-071h 04
THE ECOMMERCE EDGE Podcast with Jason GreenwoodE428:📦WHAT IT TAKES TO SUCCEED WITH B2B ECOMMERCE IN THE LIFE SCIENCES SPACE! | EVIHN VASZILY - ILLUMINA | B2B COMMERCE CORNER #71 | THE ECOMMERCE EDGE Podcast📦Evihn (https://www.linkedin.com/in/evihnv) is the Global Manager, Omni-Channel Marketing for Illumina - https://www.illumina.com
📦Illumina is a global genomics and human health leader innovating the future of precision health
📦Illumina develops DNA sequencing and array-based life sciences technologies to enable boundless research discovery and personalized health
📦Illumina products help pioneer advances in oncology, genetic and infectious diseases, reproductive health, and beyond
📦In this episode, Jason & Evihn discuss some of the unique complexities of operating a B2B eCommerce function in the Life Sciences world and how Illumina is...2024-10-0242 min
Explain PodcastE11: MGI DNA Nanoball sequencingRolling in circles to make DNA yarnsChapters:00:00 Bioinformatics Upper Crust Tools04:04 STAR05:00 MGI15:00 Daniels first contact20:00 Brief Market Overview22:30 Short read market26:00 DFG High Costs Sequencing Projects Application29:20 QuickGen: Introns and Exons35:00 ConclusionMGI vs Illumina: https://alitheagenomics.com/blog/how-do-rna-seq-results-compare-between-illumina-and-mgi-sequencing-platformsRolling the circle: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5568012/pdf/nihms894568.pdfMGI vs Illumina legal...2024-07-0236 min
Podcast Cruzamento82: Tiago Magalhães: Unveiling the Genomic Frontier [EN]In this episode of the CRUZAMENTO Podcast, hosts André Correia and Daniel Guedelha dive deep into the world of gene sequencing, rare diseases, and the future of healthcare with their guest, Tiago Magalhães. Tiago, a biologist turned bioinformatician, sheds light on the pivotal role of gene sequencing in modern healthcare and its potential to revolutionise patient care. From deciphering the intricacies of raw genomic data to the challenges and opportunities presented by initiatives like the Emirati Genome Program, Tiago provides valuable insights into the intersection of technology and healthcare. The conversation touches upon the high prevalence of rare di...2024-05-0732 minPodcast Cruzamento82: Tiago Magalhães: Unveiling the Genomic Frontier [EN]In this episode of the CRUZAMENTO Podcast, hosts André Correia and Daniel Guedelha dive deep into the world of gene sequencing, rare diseases, and the future of healthcare with their guest, Tiago Magalhães. Tiago, a biologist turned bioinformatician, sheds light on the pivotal role of gene sequencing in modern healthcare and its potential to revolutionise patient care. From deciphering the intricacies of raw genomic data to the challenges and opportunities presented by initiatives like the Emirati Genome Program, Tiago provides valuable insights into the intersection of technology and healthcare. The conversation touches upon the high prevalence of rare di...2024-05-0732 min
Podcast Cruzamento82: Tiago Magalhães: Unveiling the Genomic Frontier [EN]In this episode of the CRUZAMENTO Podcast, hosts André Correia and Daniel Guedelha dive deep into the world of gene sequencing, rare diseases, and the future of healthcare with their guest, Tiago Magalhães. Tiago, a biologist turned bioinformatician, sheds light on the pivotal role of gene sequencing in modern healthcare and its potential to revolutionise patient care. From deciphering the intricacies of raw genomic data to the challenges and opportunities presented by initiatives like the Emirati Genome Program, Tiago provides valuable insights into the intersection of technology and healthcare. The conversation touches upon the high prevalence of rare di...2024-05-0732 minIllumina Genomics PodcastHow Do You Train Genomics AI? On Natural Selection Itself, Says VP of Illumina's AI Lab, Kyle FarhIn this podcast, Mendelspod’s Theral Timpson speaks to Kyle Farh, VP and distinguished scientist leading Illumina’s Artificial Intelligence Lab. Farh says the company began the AI lab seven years ago when deep learning was just taking off. Two of the team’s AI algorithms, PrimateAI-3D and SpliceAI, published in Cell and Nature Genetics, were among the first examples of deep learning algorithms in genomics. This interview takes a close look at Illumina’s activities in AI and delves into the long-term impact of AI on genomics.2024-04-1828 min
Ordinarily Extraordinary - Conversations with women in STEM124. Dr. Chanfeng Zhao - Chemist; Chemical Engineer; EntrepreneurDr. Chanfeng Zhao is the VP of R&D Chemistry at TriLink BioTechnologies. She has over 25 years of experience in nucleotide and modified nucleotide chemistry for sequencing and genomics applications. She co-founded MyChem LLC, a company later acquired by TriLink, specializing in ultra-pure synthetic nucleotides. Chanfeng was the CSO and Co-founder of Sequlite Genomic (acquired by Fapon International), a company that was developing NGS instruments and reagents. Previously, Dr. Zhao was one of the first employees at Illumina, where she developed oligonucleotide attachment chemistry for BeadChip products. She holds a Ph.D. in Chemistry from SUNY Buffalo and a...2024-03-271h 02
Explain PodcastSE3: PhiX / UMIs / QCGetting the most out of MachinesChapters:00:00 PhiX14:30 low complexity19:30 UMIs32:10 FastQC43:00 MultiQC56:40 PycoQCPhiX concentrations for loading a validation run:https://knowledge.illumina.com/instrumentation/general/instrumentation-general-reference_material-list/000001536Dnatech on why UMIs are used:https://dnatech.genomecenter.ucdavis.edu/faqs/what-are-umis-and-why-are-they-used-in-high-throughput-sequencing/BMH learning on UMIs: https://www.youtube.com/watch?v=sRPMsnhIBK0FastQC for QC of .fastq(.gz) files:https://www...2024-02-091h 10
Explain PodcastE8: NanoporePushing spaghetti through holesChapers:00:00 Intro11:15 Measuring Ions17:00 Quality23:00 Duplex24:30 MinION25:15 PromethION28:20 Methylation29:00 Direct RNA sequencing38:25 Basecalling46:00 Basecalling bias53:50 Sequencing proteins- Nanopore explainer: https://nanoporetech.com/applications/dna-nanopore-sequencing- Oxsci explaining the technology:https://oxsci.org/pore-over-this-advances-in-dna-sequencing/- History of Nanopore:https://www.whatisbiotechnology.org/index.php/science/summary/nanopore/nanopore-sequencing-makes-it-possible-to-decode-the...2024-01-1657 min
Explain PodcastE6: Illumina Sequencing Part IIGlued DNA bridges and rainbow clustersChapters:00:00-Flowcells03:40-DNA glued to glass09:00-Bridge amplification15:50-Cluster density and patterned Flowcells28:30-Illumina SBS summary30:30-Limits33:00-Multiplexing and Demultiplexing- enseqlopedia on patterned vs unpatterned flowcell:http://enseqlopedia.com/2016/01/almost-everything-you-wanted-to-know-about-illumina-hiseq-4000-and-some-stuff-you-didnt/- ClevaLabs on Illumina sequencing: https://www.youtube.com/watch?v=WKAUtJQ69n8- Yourgenome on how the Illumina workflow works...2023-12-0138 min
Explain PodcastE5: Illumina Sequencing Part IColour mixing in PHRED spaceChapters:00:00 Nucleotides level 209:00 Cycles12:00 Not-so-wobbly mutations15:30 Reducing colourspace22:30 Cutting connections28:14 Costs and PHRED- ClevaLabs on Illumina sequencing: https://www.youtube.com/watch?v=WKAUtJQ69n8- Yourgenome on how the Illumina workflow works:https://www.yourgenome.org/facts/what-is-the-illumina-method-of-dna-sequencing/- DNATech comparing Illumina Machines:https://dnatech.genomecenter.ucdavis.edu/illumina-high-throughput-sequencing/...2023-11-1334 min
Explain PodcastE4: Ion Torrent SequencingH+ ions and where we can find themChapters:00:00 Intro04:26 pH08:04 DNA Polymerase reaction with H+12:30 Nucleotides16:30 Homopolymer problem, but different19:30 PCR is mean to some bases24:30 AmpliSeq33:40 Today’s status38:58 cfDNA40:00 PHRED vs Qscore44:59 Chip scaling and prices51:00 Outro- bitesizedbio on the technology:https://bitesizebio.com/27399/all-in-the-chip-ion-torrent-sequencers/- Quick explainer from Basic Biochem: https://www.youtube.com/watch?v=vMUnN2Y48Us...2023-09-2252 min
Conversations in Fetal MedicineIn conversation with Professor Mark KilbySend us a textWelcome to the fifth and final episode of this first season of Conversations in Fetal Medicine, where we talk to Professor Mark Kilby. In his present role, Professor Kilby works within the Medical Genomics Research Group within Illumina with members both within Cambridge and San Diego. The Group Leader is Dr David Bentley, Vice President and Chief Scientific Officer, who was one of the principal researchers involved in using next generation sequencing to unlock information of the human genome and then to apply this to the 100,000 genome project in the UK....2023-05-0345 min
LifeLines by Biocom CaliforniaEpisode 2: Democratizing Sequencing to Address Genomic Data Inequality and Improve the Future of MedicineElement Biosciences is on a mission to democratize next-generation sequencing by helping scientists overcome a major lack of diversity in genomic studies. A recent article in Nature Medicine cited that as of June 2021, 86 percent of genomics studies have been conducted in individuals of European decent, leaving researchers without adequate data representing our global population. The promise of genomic research equates to improving our understanding of disease etiology, early detection and diagnosis, drug design and clinical care. Without representation of all populations, we’re missing a big piece of the puzzle that allows the advancement of health for humanity. By re...2023-04-2626 min
If Not Now Wen PodcastCatalyzing Innovation - Interview with Jason ScharfIn today’s episode of If Not Now Wen, we’re excited to talk with special guest Jason Scharf. Jason is a bio strategy leader and active early-stage investor in the life science and digital health sectors. He has built and led teams in strategic planning, market intelligence, and innovation at large biopharma, genomics, and medtech companies.
In addition to his roles within the corporate environment, Jason has served as a co-fund manager of the San Diego Angel Conference, an investor with NuFund Venture Group, and a mentor with both the NexCubed Digital Health Acce...2022-12-2054 min
yWhalesInnovating Individual Ownership of Healthcare Information with Jenny Diggles and Michael Nova of JennyCoIn this episode, the yWhales team speak with the co-founders of JennyCo, Jenny Diggles and Michael Nova. Jenny and Michael discuss how JennyCo will change healthcare by putting the consumer in charge with Web3.0. They talk about how the JennyCo app collects and aggregates medical records and preferences, securely and privately on the blockchain and how they will protect user data.
yWhales Website: ywhales.com
Podcast Library: ywhales.com/podcasts
YouTube: https://links.ywhales.com/YouTube
Vimeo: https://links.ywhales.com/Vimeo
LinkedIn: https://links.ywhales.com/Li...2022-10-1449 min
Law, disruptedHow a Chinese Company won $330M Patent Victory in Delaware Against Leading American CompanyIn this episode of Law, disrupted, John is joined by David Bilsker, partner at Quinn Emanuel & co-chair of the biotechnology practice, and Margaret Shyr, associate at Quinn Emanuel. David and Margaret represent a Chinese-based DNA sequencing company, BGI (Beijing Genomics Institute), which recently made headlines in China for winning the largest ever U.S. jury award for a Chinese-based company. In this episode, John discusses how BGI ultimately prevailed against the U.S.-based leader in the DNA sequencing field, Illumina—not only in achieving this record-breaking jury verdict but also invalidating Illumina patents that were the cornerstone of it...2022-10-0546 min
DNA Today: A Genetics Podcast#195 Genetic Testing Industry with Tod KlinglerHelp us to defend our title as the Best Science and Medicine Podcast! Go to podcastawards.com and select “DNA Today” in the Science and Medicine category. Bonus if you tweet/post that you nominated DNA Today (and tag us), then we will share your post and give you a shoutout on the show as a thank you. You have the power to get DNA Today nominated again!
Our guest this week is Dr.Tod Klingler, who is the head of product research and development at Genomic Life. Over his 25-year career, Dr. Klingler has held...2022-07-2934 min
The Executive PodcastThe Best Idea Wins with Jason ScharfJason Scharf is an experienced strategy executive and active angel investor in the life science and digital health sectors. For the past 15 years, he has built and led teams in strategic planning, market intelligence, and innovation. Today he is the Vice President of Strategy and Partnerships for Kean Health a direct to consumer at home genomic and microbiome testing company.Connect with Jason on LinkedIn and make sure to check out Kean Health.In this conversation, Jason and I discuss the importance of being data driven, finding and setting your north star, and how the...2022-04-1239 min
Making Waves at C-Level: Business Tips for Executives, Leaders, and EntrepreneursNot The Next Silicon Valley - The Next Austin (with Jason Scharf)The ecosystem of Austin has proven over the last thirty years to produce the hottest boom town in business. Today's episode covers the "Secret Sauce of Austin" and what are the six "superpowers" of the region. According to Jason Scharf, this is a roadmap for other areas of the country (and the world) who want to grow their economies. It's not about copying Austin (or the Silicon Valley), it is about developing your own superpowers.About Jason ScharfJason Scharf is an experienced strategy executive and act...2022-04-0831 min
High Performance LongevityHealth Starts With Your Oral Microbiome | Brian Maurer @ Bristle HealthThe cleanest, pasture-raised, biodynamic, grass-fed, organic food won't do an unhealthy mouth much good. Even before digestion, with every bite, pathogens can enter the bloodstream through infected gums. Increasing permeability of the blood-brain barrier and leading to neuroinflammation. Brushing and flossing are a good start. But our one or two annual trips to the dentist puts us in reactive mode. Holistic health is about prevention, so why should oral care be any different? What my mouth needs will differ from yours. That's where Bristle can help. Meet our guest Brian Maurer started his career in genomics, at the DNA sequencing...2022-03-2452 min
THE ONE'S CHANGING THE WORLD -PODCASTAI & GENOMICS ENABLED PRECISION MEDICINE, DIAGNOSTICS FOR TB- AVLOKITA TIWARI - CTO : AarogyaAI#ai #genomics #aarogyaai #precisionmedicine #tubercolosis
AI & GENOMICS ENABLED PRECISION MEDICINE, DIAGNOSTICS FOR TB Avlokita Tiwari is a bioinformatician from the University of Turku, Finland. Her expertise lies in computational biology and genomic data. Her skill set makes her computational and machine learning skills at par with her understanding of microbiology, creating a bridge between biology and the AI/ML to drive the vision of AarogyaAI. AarogyaAI is an AI-enabled SaaS that diagnoses drug-resistant tuberculosis (DR-TB) in hours instead of weeks, AarogyaAI’s drug susceptibility test ensures patients have prescribed the most effective drugs, 100X faster than the ex...2022-03-0723 min
Alira Health's Transformation TalksAn Advanced Perspective on Advanced Diagnostics: A Roadmap to the Future of GenomicsThe advanced diagnostic ecosystem and genetic data have the power to transform healthcare systems, improve patient outcomes, and revolutionize the efficiency of care delivery.Learn more about the impact of advanced diagnostics on healthcare systems globally. Our 'Transformation Talks’ podcast, will feature guests from Illumina, one of the leading companies in next-generation sequencing (NGS), who will discuss NGS technology, how patients benefit globally from groundbreaking sequencing techniques, and what are the key barriers to adoption of genomics in patient care, and the importance of both education and real-world evidence (RWE): Brock Schroeder, Senior Director, Global Market Acc...2022-02-1132 min
Spotlight on Women in Health VenturesRedefining Research through Transparency in Data Sharing with Dawn Barry (LunaDNA)Dawn Barry is the president and co-founder of LunaPBC, which is the public benefit corporation that launched LunaDNA, the first DNA and health research platform owned by its community of data donors. LunaDNA's member-owned digital data-sharing community makes discovery representative of the real world and aligned with people’s true goals by giving all individuals a role in research. Previously, Dawn joined Illumina in 2005 and served as the Vice President of Applied Genomics. Prior to Illumina, Dawn worked at Genaissance Pharmaceuticals, one of the first genomics startups focused on personalized medicine. In this episode, Dawn shares lessons learned in he...2021-12-3033 min
The Harry Glorikian ShowMichael Snyder on Using Data to Keep People HealthyHaving helped to bring big data to genomics through the lab techniques he invented, such as RNA-Seq, the Stanford molecular biologist Michael Snyder is focused today on how to use data from devices to increase the human healthspan. Some cars have as many as 400 sensors, Snyder notes. "And you can't imagine driving your car around without a dashboard...Yet here we are as people, which are more important than cars, and we're all running around without any sensors on us, except for internal ones." To Snyder, smart watches and other wearable devices should become those sensors, feeding information to...2021-06-0755 min
Micro binfie podcast47 SARS-CoV-2 Rapid roundup and questions answeredWe present a rapid round up of SARS-CoV-2 questions and issues, hopefully with some answers, so that you can stay on top of the latest in SARS-CoV-2 genomics. Recorded 5 February 2021.
Topics covered:
Why missing 1 SNP can cause lineage assignment to break and how it works?
How do we describe lineages with a chain of mutation events?
Are we seeing convergent evolution?
Co-infections of different lineages discovered?
For nanopore basecalling do use HAC & should you get a GPU?
Basic logistics difficult for sequencing in many parts of world.
Can I look at recombination with ARTIC on Illumina?
How do you annotate...2021-02-0832 min
The Reagent PodcastThe Intersection of Life Sciences and Communication w/ Paul BromannPaul Bromann received his PhD in neuroscience in 1999 from Northwestern University. He currently serves as a medical science partner for Rare Diseases at UCB, a global biopharma company focusing on neurology and Immunology. At the time of this recording, Paul was actually at his previous employer Illumina, where he led a team of scientists to drive awareness and knowledge in genomics, since he's no longer at Illumina. Some small details of this episode may be out of date. I still think you'll get plenty of value learning about his journey, like how he went from...2020-06-1015 min
Once a Scientist5. Illumina Genomics Podcast host, Paul Bromann, on effective science communicationEpisode 5. Paul Bromann is the host of the Illumina Genomics Podcast and Senior Manager of Scientific Affairs at Illumina. He did his PhD in neuroscience at Northwestern University and postdocs at Sanford-Burnham Prebys and Van Andel Institute. He's had extensive industry experience, including a stint as a Medical Science Liaison at Bristol-Meyers-Squibb.2020-04-0156 min
Precisione: The HealthcastPrecision Approach to ProbioticsGuest Name and Bio: Suneer “Sunny” Jain, M.S., Chief Executive Officer, Sun Genomics. Mr. Jain earned his Bachelor of Science (B.S.) degree from the University of Iowa in 1999. He went on to graduate with a Masters in Anatomy and Cell Biology from the Department of Anatomy and Cell Biology at the University of Iowa in 2004, where he conducted research in the field of Microbiology and Gene Therapy. Following graduation, Mr. Jain began his career as a Research and Development Supervisor for Pathway Diagnostics. Here he developed new molecular biomarker assays for clinical trials and...2020-03-2034 minIllumina Genomics Podcast2019 and the Year in GenomicsIn 2019, NGS continued to enable scientists to make great strides in understanding human biology and disease. In this special compilation episode, I’ll share some of our 2019 podcast highlights. We’ll also share our expert guests’ predictions for science, medicine, and genomics – where we were in 2019, and where we’re going in 2020 and beyond.2020-01-2225 min
How to Live to 200 PodcastCat Poop and the Secrets of the MicrobiomeIvan Liachko – Co-founder & CEO at Phase Genomics Today’s guest is Ivan Liachko. Ivan is Co-Founder and CEO of a fascinating University of Washington spinout, Phase Genomics. With 20 years of experience and a Ph.D. in Genetics, Ivan is a leading expert in genetic/genomic research. Ivan and his teams at Phase Genomics have developed a new genomic discovery that, among other things, can help lead to longer lives and new drug developments. In this episode, we learn all about Lil Bub and how the internet famous cat’s poop helped Ivan discover entirely new organi...2019-01-2331 minIllumina Genomics PodcastGenomics 2018 Looking Back and Looking Ahead2018 was an awesome year for genomics and genomics research. In this special compilation episode, I’ll share some of our 2018 podcast highlights and future predictions for genomics – where we were in 2018, and where we’re going in 2019 and beyond.2019-01-2325 min
cc: Life Science PodcastIllumina Created a Podcast to Grow the Genomics MarketIllumina has significant market share in genomics. How would they reach beyond their current users to grow the market for genomics analysis? A podcast of course! Paul Bromann is a Scientific … This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit cclifescience.substack.com2018-02-2030 min
Life Science Marketing RadioIllumina Created a Podcast to Grow the Genomics MarketIllumina has significant market share in genomics. How would they reach beyond their current users to grow the market for genomics analysis? A podcast of course! Paul Bromann is a Scientific …2018-02-2030 minLife Science Marketing RadioIllumina Created a Podcast to Grow the Genomics MarketIllumina has significant market share in genomics. How would they reach beyond their current users to grow the market for genomics analysis? A podcast of course! Paul Bromann is a Scientific … This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit cclifescience.substack.com2018-02-2030 min
She+ Geeks Out PodcastMentorship and Genetic Research with Janina JeffJanina Jeff is a Global Bioinformatics Specialist at Illumina and a genomics genius. We talked about her path to getting a PhD in Human/Medical Genetics and the importance of mentorship, both mentoring and being mentored. Janina spoke at our NYC event in November. Watch her talk here! This episode is brought to you by the good humans at August - https://aug.co. They make organizations work better. August was founded with the belief that today’s most valuable work depends on teams of people who work well together. Get their newsletter, listen to their podcast, and join the...2017-06-061h 01
a16z Podcasta16z Podcast: On the Genomics of Disease, From Science to BusinessOnce we sequenced the human genome, we'd know the cause of -- and therefore be able to help cure -- all diseases... Or so we thought. Turns out, 20,000 genes (and counting) didn't really explain why disease occurred. Sure, some could be explained by mutations in a single genome, but most, like cancer, are too damn complex. And while the focused, singular approach to understanding disease did yield some useful therapeutics, it's now reached its limits. It hasn't helped much on the diagnostics (and early detection) front, either.
That's where a systems approach to bio comes in, drawing...2016-10-1830 min