Shows
Longevity Roadmap146: AMA President Dr. Bobby Mukkamala - Healthspan-Centric Medical Care in AmericaJoining Dr. Buck Joffrey this week, Dr. Bobby Mukkamala shares his journey from aspiring cardiothoracic surgeon to becoming the president of the American Medical Association. He discusses his personal health challenges, including a brain tumor diagnosis, and how it has shaped his perspective on healthcare. The conversation delves into the importance of preventative medicine, the impact of the Flint water crisis, and the role of the AMA in shaping the future of healthcare, particularly in the realm of longevity and AI. Dr. Mukkamala emphasizes the need for a shift from reactive to proactive healthcare and addresses the challenges posed...2025-07-2839 minLongevity Roadmap145: Why Some Animals Live Longer Than Others with Dr. Steven AustadIn this conversation, Dr. Buck Joffrey and Dr. Steven Austad discusse the biology of aging, the evolutionary aspects of longevity, and the potential for genetic technologies to extend human health span. Dr. Austad emphasizes the complexity of aging, the importance of glucose control, and the need for further research into species that exhibit remarkable longevity. The discussion also touches on the challenges and ethical considerations of manipulating human genetics for longevity. Learn more about Dr. Steven Austad: https://www.stevenaustad.com/ - Download Dr. Buck Joffrey's FREE ebook, Living Longer for Busy...2025-07-2135 min
The Blank Check: How much are you worth?From Silence to Summit: What the Mountain Taught Me About PurposeSend us a text⛰️ The most life-changing moments in your life weren’t meant to be posted… but to BE IN THE MOMENT. In this raw and powerful episode of The Blank Check: How Much Are You Worth?, host Joffrey Gurule shares a personal story from a recent mountain climb in Sedona, AZ—an experience that wasn’t about content, but consecration.🙏🏽 From the pain of private struggles to the pressure of performance in business and life, Joffrey unpacks the deep truth:God does His best work when no one else is watching.🎙️ You’...2025-07-1907 minLongevity Roadmap144: Why the Brain is Especially Vulnerable to AgingIn this conversation, Dr. Buck Joffrey and Dr. Julie Andersen explore the molecular mechanisms behind neurodegenerative diseases, with a particular focus on the aging brain. They discuss the brain’s heightened vulnerability to aging, the impact of mitochondrial dysfunction, and the challenges posed by drug delivery across the blood-brain barrier. The conversation also delves into innovative strategies to support mitochondrial health, including the potential of lysosomal rejuvenators and senolytics, as well as the importance of identifying early biomarkers for neurodegenerative conditions. Dr. Andersen also underscores the critical role of lifestyle interventions—especially exercise—in mai...2025-07-1429 minLongevity Roadmap143: The Longevity Dividend with Prof. Jay OlshanskyIn this conversation, Professor S. Jay Olshansky discusses the evolution of aging science, the realistic limits of human life expectancy, and the concept of the Longevity Dividend, which emphasizes the health and economic benefits of modulating the aging process. He also explores the potential of biomarkers in predicting longevity, the societal implications of an aging population, and the ethical considerations surrounding advancements in longevity science. Learn more about Professor S. Jay Olshansky: http://sjayolshansky.com/sjo/Background.html - Download Dr. Buck Joffrey's FREE ebook, Living Longer for Busy People: https://r...2025-07-0729 minLongevity Roadmap142: The Gut-Muscle Axis with Dr. Michael Lustgarten In this episode, Dr. Michael Lustgarten discusses his research on the gut microbiome, serum metabolome, and muscle health in older adults. He shares insights from his journey into the world of aging, the importance of data in health optimization, and the emerging concept of the gut-muscle axis. Dr. Lustgarten emphasizes the significance of metabolites in predicting longevity and the need for personalized health tracking. He also addresses the balance of exercise and the role of fecal microbiota transplantation in health. Learn more about Dr. Michael Lustgarten: https://nutrition.tufts.edu/academics/faculty/michael-lustgarten Email Dr. Michael Lustgarten: mlhnrca@gmail.com 2025-06-3029 minLongevity Roadmap141: A Thermostat for Your Body FatIn this conversation, Dr. Stephan J. Guyenet joins Dr. Buck Joffrey to discuss the complex mechanisms of body fat regulation, focusing on the role of the lipostat and leptin. He explains how the body regulates fatness through hormonal signals and the implications of leptin resistance in obesity. The discussion also covers practical strategies for weight management, the impact of stress and sleep on leptin levels, and critiques of the carbohydrate insulin model of obesity. Learn more about Dr. Stephan J. Guyenet: https://www.stephanguyenet.com/ - Download Dr. Buck Joffrey's FREE ebook, Living Longer for Busy People: ht...2025-06-2329 minLongevity Roadmap138: Sleep Impact on Longevity and Health with The Sleep DoctorSleep is the secret weapon for a longer, healthier life—and Dr. Michael Breus is here to show you how to use it. In this episode of Longevity Roadmap, Buck Joffrey dives deep into the science of sleep with the world-renowned sleep doctor himself. Discover why sleep is the third pillar of longevity, how REM sleep and deep sleep fuel physical and emotional restoration, and what your chronotype reveals about your ideal sleep patterns. From the effects of sleep deprivation on metabolism and aging to natural sleep tips, supplements, and cutting-edge alternatives to CPAP machines fo...2025-06-0257 minLongevity Roadmap137: Dr. Joan Mannick - Targeting mTOR to Improve Immune Function and HealthspanWhat if targeting a single cellular pathway could slow aging and boost immunity? Dr. Joan Mannick, a leading voice in aging science, reveals how mTOR inhibitors may be the future of longevity therapeutics. From her early inspiration to groundbreaking clinical trials, Dr. Mannick explores the role of mTOR in aging, immune response, and antiviral immunity. Learn how selective mTOR inhibition could extend healthspan without compromising muscle mass, improve vaccine response in older adults, and unlock new possibilities in clinical longevity. Learn more about Dr. Joan Mannick: https://www.linkedin.com/in/joan-mannick-8089a614/2025-05-2642 minLongevity Roadmap136: Why is Vitamin D So Important in Health and Longevity?Vitamin D is more than a vitamin—it's a hormone that influences everything from your immune system to cardiovascular health, cognition, and longevity. In this conversation, Dr. Michael Holick breaks down the science of vitamin D synthesis, the truth about sun exposure vs. supplements, and why vitamin D deficiency is far more common—and more dangerous—than most people realize. You'll learn how skin pigmentation, UVB exposure, and supplementation protocols impact your vitamin D levels, and why D3 is more effective than D2. Dr. Holick also dives into mood, cognition, and the controversial role of vitamin D in chronic diseas...2025-05-1942 minLongevity Roadmap135: The Aging Brain - From Memory Lapses to Measurable PreventionIs your memory decline normal—or something more? Clinical neuropsychologist Dr. Mitchell Clionsky breaks down what healthy aging looks like from a cognitive perspective and where concern might be warranted. He introduces the Memory Orientation Screening Test (MOST)—a powerful yet quick tool to assess cognitive health—and shares insights from decades of evaluating memory, dementia, brain injuries, and CTE. From preventive strategies that could reduce dementia risk by nearly 50%, to how technology is transforming neuropsychology, this conversation is a must-watch for anyone invested in long-term brain health. Learn more about Dr. Mitchell Clionsky: https...2025-05-1231 minLongevity Roadmap134: Can You Boost Stem Cells Naturally?What if your body already had everything it needs to heal itself—naturally? In this episode, neurophysiologist and stem cell researcher Dr. Christian Drapeau breaks down the science of stem cell therapy, explaining how adult stem cells, embryonic stem cells, and exosomes play a central role in regenerative medicine and longevity. Discover how aging affects the body’s ability to mobilize stem cells, how injury signals guide them, and why immune system function is tightly linked to stem cell activity. Learn more about Dr. Christian Drapeau and STEMREGEN: https://tinyurl.com/kmvp597...2025-05-0544 minLongevity Roadmap133: Can We Reverse Immune System Aging? T Cells, Telomeres, and the Fight Against SenescenceIs it possible to rejuvenate the immune system as we age? In this episode, Dr. Alessio Lanna breaks down the science of immune aging, focusing on the critical role of T cells, telomere shortening, and senescence. He explains how T cells lose their effectiveness over time—and shares emerging research on how intercellular telomere transfer and the ESMAC complex may help reverse immune senescence. Learn how pharmacological interventions could unlock new possibilities for health, longevity, and immune rejuvenation. Learn more about Dr. Alessio Lanna: https://sentcell.life/team/ - Download Dr. Bu...2025-04-2833 minThe Blank Check: How much are you worth?The Emotional Work Out: Control the NegativeSend us a textStop feeling weighed down! 😫 This week on the award-winning podcast "The Blank Check," host Joffrey delivers a powerful message about taking charge of your response to life's difficulties 💪. Drawing inspiration from a surprising gym observation 🏋️ and the extraordinary story of Viktor Frankl ✨, this episode explores the concept of "controlling the negative" – resisting the natural urge to be overwhelmed 🌊 and instead choosing strength 🛡️. Learn practical strategies to navigate tough times: slow down your reactions 🐌, focus on your internal power (attitude 🤔, thoughts 💭, faith 🙌), and trust in a bigger plan 🌟. If you're seeking motivation 🔥 and actionable steps to build inner strength 💪 and find...2025-04-2208 minLongevity Roadmap131: Matt Kaeberlein - Aging, mTOR, Epigenetic Clocks, and more!What if aging isn’t just inevitable—but modifiable? In this episode of Longevity Roadmap, Dr. Matt Kaeberlein breaks down the science of biological aging, with a focus on mTOR, epigenetics, and the hallmarks of aging like cellular senescence, mitochondrial dysfunction, and epigenetic drift. He explores the role of genetics vs. environment, the promise and pitfalls of metformin, NAD boosters, and senolytics, and why interventions like rapamycin and caloric restriction may extend health span. From the limitations of biological age tests to the importance of lean muscle mass, this conversation is a masterclass in evidence-based longevity research. 2025-04-141h 01Longevity Roadmap130: Does the Gut Control the Brain?Dr. Michael Gershon—legendary Columbia professor and author of The Second Brain—joins us to explain why your intestines might just be running the show. From guinea pig guts that "blew back" to the real reason stress wrecks your digestion, this episode dives deep into the mysterious world of the enteric nervous system. Prepare for gut science, serotonin surprises, and a Woody Allen–esque dose of humor from the father of neurogastroenterology himself. Learn more about Dr. Michael Gershon: https://www.pathology.columbia.edu/profile/michael-d-gershon-md Download Dr. Buck Joffrey's FREE ebook, Living Longer...2025-04-0735 minLongevity Roadmap125: Reversing Skin Age - Tackling Senescence with OS-01Visit oneskin.co/BUCK and use code BUCK at checkout for 15% off your first purchase! Dr. Carolina Reis Olivera shares her journey in aging and longevity research, highlighting the development of the OS-01 peptide—a breakthrough targeting cellular senescence to improve skin health. She delves into the biology of skin aging, the impact of senescent cells, and the cutting-edge strategies OneSkin is using to combat age-related skin conditions. The conversation also explores clinical trials, product efficacy, and the broader systemic benefits of optimizing skin health. Download Dr. Buck Joffrey's FREE ebook, Living Longer for Busy Peo...2025-03-0328 minLongevity Roadmap114: Traditional Lab Studies Can Miss Deadly DiseaseIn this episode, Buck Joffrey discusses the importance of going beyond the normal scope of testing when it comes to lipid profiles and cardiovascular health management. He emphasizes the significance of understanding cholesterol particles, particularly APO-B, and lipoprotein(a), in assessing heart disease risk. He also highlights preventative strategies to optimize health and mitigate risks associated with cardiovascular disease.2024-12-1620 minLongevity Roadmap113: Lipid Management with Coronary Artery Disease and e2/e4 GenotypeIn this episode of Longevity Roadmap, Buck Joffrey presents a case study of a 70-year-old patient with optimal metabolic health but elevated LDL and APOB levels, emphasizing the importance of aggressive lipid management in preventing coronary artery disease. Buck also explores the genetic factors related to Alzheimer's risk and the implications of lipid levels on cognitive health, advocating for proactive treatment strategies. 00:00 - Introduction to Longevity Roadmap 03:08 - Case Study: A 70-Year-Old Patient's Health 12:07 - Understanding Lipid Management and Atherosclerosis 19:49 - Genetic Factors in Alzheimer's Risk and Lipid Management2024-12-0918 min
Wealth Formula by Buck Joffrey481: Finance and Market News 11/27/24Buck Joffrey and Zulfi Ali tackle critical issues shaping the U.S. economic landscape, from the mounting government debt and entitlement challenges to the looming risks of a debt crisis. They examine the current state of U.S. debt, its global context, and the future of treasury auctions, emphasizing the unsustainable debt-to-GDP trajectory and the political hurdles in reforming entitlements.
The conversation also delves into the economic ripple effects of the Trump administration’s policies on inflation, growth, and the stock market, alongside the shifting dynamics of treasury yields. Buck and Zulfi explore the evolving cryptocurrency market, fo...2024-11-2742 min
Wealth Formula Podcast481: Finance and Market News 11/27/24Buck Joffrey and Zulfi Ali tackle critical issues shaping the U.S. economic landscape, from the mounting government debt and entitlement challenges to the looming risks of a debt crisis. They examine the current state of U.S. debt, its global context, and the future of treasury auctions, emphasizing the unsustainable debt-to-GDP trajectory and the political hurdles in reforming entitlements. The conversation also delves into the economic ripple effects of the Trump administration’s policies on inflation, growth, and the stock market, alongside the shifting dynamics of treasury yields. Buck and Zulfi explore the evolving cryptocurrency market, focusing on Solana an...2024-11-2742 minThe Blank Check: How much are you worth?Meeting Jesus on E StreetSend us a textIn this episode, host Joffrey takes us on a heartfelt journey through two distinct encounters that shaped his perception of faith and compassion. As a child, he vividly recalls a moment when he thought he saw Jesus walking down E street, a memory that has stayed with him throughout his life. Fast forward years later to a chance encounter with a homeless person in New Orleans. Alongside his daughter, she opens his eyes to a new understanding of spirituality. Through his daughter's act of compassion, Joffrey comes to realize that we can h...2024-10-1711 minWealth Formula by Buck JoffreyHas the first person to live to 500 already been born?Buck introduces his brand new health and longevity podcast, Longevity Junky.
Longevity Junky is a compelling and accessible new podcast that works for all longevity enthusiasts, whether you’re a hardened scholar who craves detailed science or a relative newcomer to this fascinating and quickly evolving world.
Dr. Buck Joffrey, MD, is a former neurosurgeon, successful entrepreneur, and self-described health-conscious hedonist.
Nikki Leigh is a jet-setting actress influencer with 6M followers and is the OG Longevity Junky.
They’re good friends and willing guinea pigs for all longevity-related experiments.
From...2024-09-1356 minWealth Formula PodcastHas the first person to live to 500 already been born?Buck introduces his brand new health and longevity podcast, Longevity Junky. Longevity Junky is a compelling and accessible new podcast that works for all longevity enthusiasts, whether you’re a hardened scholar who craves detailed science or a relative newcomer to this fascinating and quickly evolving world. Dr. Buck Joffrey, MD, is a former neurosurgeon, successful entrepreneur, and self-described health-conscious hedonist. Nikki Leigh is a jet-setting actress influencer with 6M followers and is the OG Longevity Junky. They’re good friends and willing guinea pigs for all longevity-related experiments. From hallucinogens to full body MRIs, micro-dosing Cialis to tech, exercise, and d...2024-09-1356 minThe Blank Check: How much are you worth?I AM Mindset Guided Meditation: The MountainSend us a textWelcome,In this guided meditation you will embark on a journey to lift you from a feeling of being clouded to a viewpoint of clarity. Our guide Joffrey will walk you though a mental journey from the pit of your struggle situation to the peak of your inner freedom.Suggestions for Best ExperienceFind a comfortable seated positionSilence your phone from notificationsKeep your eyes closed and focus on your thoughtsMaintain a soft slow rhythm of breathingListen with headphonesHow are you feeling?2024-08-0706 minLongevity Roadmap89: The Nine Pillars of Resilience with Stephen Sideroff, PhDBuck Joffrey, MD discusses the concept of resilience with Stephen Sideroff, PhD. Topics include bouncing forward from stress and practical techniques to restore balance, nurture growth, and slow down the aging process. 01:35 Defining Resilience and the Ability to Adapt 08:21 Physical Balance and Mastery: Restoring Balance in the Nervous System 15:26 Self-Relationship: How It Changes Your Physiology 21:47 Resilience and Longevity 23:16 Emotion Balance and Mastery2024-06-2428 min
Existential and Okay28. Just Joff (ft. literally just Joffrey)It's me, and only me on this episode. Like me or hate me I think I had fun recording this episode. Talking out loud to yourself is way more interesting than you might ever think. Friends are important and the Olympics are fun. Be blessed good people of the internet.
Music from #Uppbeat (free for Creators!):
https://uppbeat.io/t/jeff-kaale/moonlit
License code: NVUGXDWZ0B3WMPLJ
2024-06-1349 minLongevity Roadmap86: The Science of Human AttractionBuck Joffrey, MD reviews the literature on the topic of human attraction. Topics include the brain, perception of beauty, specific aspects of beauty, and sexual dimorphism. Also included is a discussion on the role of human pheromones and attraction. Show Notes: 01:20 Facial Attraction & Cues 08:30 Facial Symmetry 11:12 The Averageness of Facial Features 13:59 Clear and Unblemished Skin 15:44 Sexual Dimorphic Traits 22:23 Smell and Pheromone2024-06-0329 minWealth Formula by Buck Joffrey431: Wealth Formula Banking Webinar ReplayBuck Joffrey is joined by Rod Zabriskie and colleagues of Wealth Formula Banking to discuss this powerful financial tool that leverages your savings to invest the same money at two places at the same time.
2024-05-2400 minWealth Formula Podcast431: Wealth Formula Banking Webinar ReplayBuck Joffrey is joined by Rod Zabriskie and colleagues of Wealth Formula Banking to discuss this powerful financial tool that leverages your savings to invest the same money at two places at the same time.2024-05-2431 minLongevity Roadmap84: Keto Diet 101Buck Joffrey, MD discusses the basics of the keto diet with Amy Berger, a certified nutrition specialist. Topics include the definition of the diet, its health benefits and its role in the treatment of various disease processes including type 2 diabetes and Alzheimer’s Disease. Show Notes: 03:08 Why the Keto Diet? 04:15 How Does the Keto Diet Help You Lose Weight? 05:51 Other Benefits of the Keto Diet 09:14 How Does High Blood Sugar Result in Insulin Resistance? 11:44 What Defines a Keto Diet 16:13 Lifestyle VS Intervention 19:02 The Co...2024-05-2034 minLongevity Roadmap83: Sexually Transmitted CancerBuck Joffrey, MD reviews what is known about sexually transmitted cancers. Discussion includes HIV and Hepatitis but focuses on Human Papilloma Virus which Buck believes is grossly underappreciated by people and by physicians. 01:18 HIV 05:26 Hepatitis 09:20 HPV2024-05-1322 minLongevity Roadmap82: Intro to the MicrobiomeBuck Joffrey, MD provides an introduction to the microbiome and discusses its importance. Topics also include prebiotics, probiotics, and postbiotics.2024-05-0624 minLongevity Roadmap81: Ask the Doctor 04/29/24Buck Joffrey, MD, takes questions from the audience. Topics include human growth hormones, the potentially harmful effects of an MN, 40 Hz therapy, and visceral fat. Show Notes: 00:47 Is It Fine That I Sleep Too Much? 08:08 The 40hz Gamma Frequency and How It Relates to Brain Health 13:28 The Anti-Aging Effects of Human Growth Hormone 20:31 Reconsideration of How to Fast 29:22 Potentially Harmful Effect of NMN 33:08 Visceral vs Subcutaneous Fat 2024-04-2937 minLongevity Roadmap80: The Longevity Diet with Valter Longo, PhDBuck Joffrey, MD, discusses the fasting regimen with Dr. Valter Longo, PhD. Dr. Longo is a world, renowned researcher in longevity and the author of: The Longevity Diet. Show Notes: 01:10 Types of Fasting 03:31 Why Fasting is Beneficial From a Cellular Level 07:00 Intermittent Fasting VS Fast Mimicking Diet 14:05 How Does Fasting Help Cancer Patients 20:37 What Is in the Fast Mimicking Diet 33:38 Pills and Supplements for Fasting Mimicking Diet 41:23 Time-Restricted Feeding Based on Circadian Rhythm 2024-04-2254 minWealth Formula by Buck Joffrey423: Campbell Harvey Says the Fed is WRONG on Inflation and Interest RatesEven really smart people are wrong on a regular basis. I see this all the time in health and longevity-related issues on my other podcast, Sapio with Buck Joffrey.
In case you are wondering…yes, I have become one of those middle-aged California guys trying to stay young at all costs. Not easy. But, I have to admit, the nerdy physician scientist type in me is having lots of fun with the science and enjoying the process of sharing it with my fellow Gen-Xers who are also fighting gravity with me.
But getting back to th...2024-04-2139 minLongevity Roadmap79: Lies Taught in Medical School: Robert Lufkin, M.D.Buck Joffrey, MD interviews Robert Lufkin, MD about his book Lies I Taught in Medical School: And the Truths That Can Save Your Life Topics include metabolic syndrome, intermittent fasting, and various outdated information still used in mainstream medicine that may have deleterious effects on people’s health. Show Notes: 01:35 Dr. Lufkin’s Personal Journey to Question the Medicine Establishment 04:14 When Did People Start to Take Metabolic Syndrome Seriously? 08:33 What Exactly is Metabolic Syndrome from a Physiological Standpoint? 10:21 The Balance Between Building and Breaking Down in the Meta...2024-04-1538 minThe Blank Check: How much are you worth?The Journey of LifeSend us a textHello Dream Chasers,This week on "The Blank Check," we delve into a story of personal revelation set against the backdrop of a silent night drive through the California desert. Our host shares a powerful moment of self-realization about the importance of following one's dreams and being a present parent.Are you living true to your aspirations? Listen to this episode to find inspiration to follow your dreams and make every moment with your loved ones count.Keep dreaming,Joffrey GSound Edits...2024-04-1210 minLongevity Roadmap78: The Age of Data-Driven Wellness is HereDr. Buck Joffrey, M.D. interviews, Dr. Nathan Price, PhD from Thorne about a new paradigm in medicine driven by data, technology, and self-empowerment. Show Notes: 00:58 What Really is Healthspan? 05:06 Biological Age VS Chronological Age 07:41 The Factors that Determine Biological Aging 12:08 What Happens When You Artificially Suppress These Factors 16:58 What is Phenomics and how can it predict diseases? 24:21 How Can You Do Self Tests?2024-04-0831 minLongevity Roadmap76: Intermittent Fasting Correlated to Higher Risk of Cardiovascular DeathIn this episode of Sapio, Dr. Buck Joffrey, MD addresses the recent American Heart Association study correlating intermittent fasting/time restricted, feeding to higher rates of cardiovascular death. Buck breaks down what we already know about the data behind intermittent fasting in both animals and in humans and tries to put the most recent study into context. He provides feedback on the study itself, including some suggestions on how to use this new information. Show Notes: 02:01 Intermittent fasting vs caloric restriction 06:57 Why Intermittent Fasting Improves Metabolic Health 10:19 Intermittent fasting while maintaining...2024-03-2527 minLongevity Roadmap75: Stress, Cortisol and Prevention StrategiesBuck Joffrey, MD talks to Romie Mushtaq, MD regarding stress, cortisol levels and prevention strategies including meditation and anti-inflammatory diets. Show Notes: 02:14 The definition of stress 13:16 Why does stress disrupt circadian rhythms and sleep 16:08 How do we treat stress? 21:23 Nootropics 24:39 Vagal nerve stimulator 28:34 Digital detox and meditation 33:02 Diet for stress 2024-03-1846 minLongevity Roadmap74: Aggressive Male TRT Approach, Erectile Dysfunction Drugs, and Alzheimer’s DiseaseBuck Joffrey MD speaks to Justin Houman MD who is a urologist regarding the idea of aggressive testosterone treatment to decrease the risk of metabolic syndrome and therefore multiple other disease processes that are downstream. Other topics disgust include erectile dysfunction, early treatment with ED meds and the correlation with Alzheimer’s disease. Show Notes: 1:27 Is it true that the testosterone in men in general has gone down? 02:43 Common symptoms of low testosterone 05:15 Normal level of testosterone 07:19 Testosterone and metabolic syndrome 12:49 Testosterone replacement therapy and cancer 2024-03-1145 minLongevity Roadmap73: Is a Vegan Diet Healthy?Buck Joffrey, MD and Linda Tyler, PhD discuss the topic of plant-based only/Vegan diets. The conversation includes topics on inflammation and nutritional concerns. Show Notes: 2:55 A plant-based diet for better health? 11:53 Balancing nutritions for the plant-based diet 20:39 Accessibility of the plant-based diet 22:30 Processed plant-based food 2024-03-0434 minLongevity Roadmap72: A Different Framework for Health?Buck Joffrey, MD interviews Anoop Kumar, MD on his perspective on health and wellness. Dr. Kumar is an emergency medicine doctor who is also knowledgeable about traditional Indian Philosophy and medicine. Show Notes: 00:43 Near-Death Experience and Shift in Perspective 07:04 The Three Minds Framework 23:03 Reevaluating the Model of Human Anatomy 27:20 The Four Engines: Nutrition, Movement, Connection, and Rest 39:24 The Four Engines of Health and Healing 41:01 Harnessing the Placebo Effect and Self-Healing 2024-02-2649 minLongevity Roadmap70: The Science Behind Music and Mental HealthBuck Joffrey, MD interviews Dr. Daniel Bowling from Stanford University on the science behind music and mental health. Bowling discusses the fundamentals of musicality and the research that has been done in this relatively new field of music as treatment for health-related issues. Show Notes: 02:59 What is musicality? 04:47 What is tonality? 07:05 How does music affect the brain? 11:20 Music as treatment for mental health 22:22 Does music sharpen our intellect? 27:05 Musical vs pharmaceutical interventions 30:38 How to get started on music therapy2024-02-1237 minWealth Formula by Buck Joffrey413: Social Security Scams and “Retirement” PlanningRetirement means “ceasing to work”. In my case, retirement will describe me when I’ve died.
I understand retiring from a particular activity. Like how I retired from the practice of surgery about eight years ago. But global retirement sounds dire.
It is like admitting that you are of no real value to the world anymore. That your contributions are no longer of benefit to humanity.
I’ve always believed that the universe ultimately pays you what you deserve. If all you’re doing is playing golf, you aren’t worth a dime.
And im...2024-02-1140 minLongevity Roadmap69: Glutathione: The Master AntioxidantBuck Joffrey, MD welcomes pharmacist and glutathione expert Dr. Nayan Patel. This podcast discusses the role of glutathione as an antioxidant including why it is known as the "master" antioxidant. The discussion reviews the physiology of glutathione in the body focussing on disease prevention and also discusses different mechanisms of supplementation. Show Notes: 00:48 What is oxidative stress? 04:12 What is an antioxidant and how does it work? 10:24 Glutathione and its relationship to longevity 29:12 Dr. Patel’s Auro Wellness2024-02-0548 minLongevity Roadmap67: The Silent Global Epidemic KillerBuck Joffrey, M.D. discusses metabolic syndrome which affects 1/4 of the global adult population and how it underlies the development of virtually every other major cause of death. Show Notes: 00:13 Understanding Metabolic Syndrome 05:29 Criterias of Metabolic Syndrome 23:40: Insulin Resistance and Hyperinsulinemia 24:49: Metabolic Syndrome and Diabetes 37:49: Recommended Lab Tests 42:05: The Health Implications of Liposuction 50:42: The Importance of HSCRP 2024-01-2246 min