Shows
Innovating Tomorrow's MedicineSneak Peek: Targeting mRNA with Small Molecules: David Weitz, Syrna TherapeuticsWhat if we could stop disease-causing proteins before they're even made—using small molecules to target their mRNA?David Weitz, CEO of Syrna Therapeutics, is pioneering exactly that: 3D structure-guided drug discovery for mRNA, coupled with covalent translation inhibitors that silence proteins at the source.🎙️ Full episode drops 7 January 2026In the complete interview, we dive into:• Why mRNA is an untapped drug target• 3D structure-guided discovery and covalent inhibitors• Lead programs in immunology and neurodegeneration• Building Syrna and coming out of stealthSubscribe so you don't mi...
2026-01-0701 min
Innovating Tomorrow's MedicineTargeting mRNA with Small Molecules: David Weitz, Syrna TherapeuticsWhat if we could silence disease-causing proteins not by targeting the protein itself, but by preventing its mRNA from ever being translated—using small-molecule drugs?In this episode, David Weitz, Co-founder, President and CEO of Syrna Therapeutics, shares how his company is pioneering a revolutionary approach: 3D structure-guided drug discovery for mRNA, coupled with covalent translation inhibitors that block disease-causing proteins before they're even made.What we discuss:• Why mRNA represents an untapped class of small-molecule drug targets• How covalent translation inhibitors work to silence protein expression• 3D structure-guided drug dis...
2026-01-0755 min
Innovating Tomorrow's MedicinePredicting Patient Response Before Trials Start: Pilgrim Jackson, Yatiri BioWhat if you could know before a clinical trial which patients will respond? Not after Phase 2 fails. Not after spending $50M. Before you even start.In this episode, Pilgrim Jackson, CEO of Yatiri Bio, shares how his company is using proteomics to predict treatment response in AML and ovarian cancer with 100% accuracy so far.What we discuss:• How proteomic signatures differentiate responders from non-responders in AML and ovarian cancer• Why this could reduce Phase 2 trial enrollment from 100 patients to 40—cutting costs in half• De-risking clinical trial design and addressing patient...
2025-12-1950 min
Innovating Tomorrow's MedicineSneek Peak: Pilgrim Jackson on Yatiri Bio and decoding proteins to predict treatment responseWhat if you could know before enrolling a single patient which ones will actually respond to treatment?Pilgrim Jackson, CEO of Yatiri Bio, is using proteomics to predict treatment response in AML and ovarian cancer with 100% accuracy so far—potentially cutting Phase 2 trials from 100 patients to just 40.🎙️ Full episode drops December 18In the complete interview, we dive into:• Proteomic signatures that differentiate responders from non-responders• De-risking clinical trials and addressing patient heterogeneity• Regulatory strategy for biomarker-driven trials• The future of precision oncologySubscribe so you don't mi...
2025-12-1201 min
Innovating Tomorrow's MedicineCytisinicline and the Future of Nicotine Dependence: Rick Stewart, Achieve Life SciencesWhat if we could help millions quit smoking with a naturally derived compound that's been used for decades—but never brought to the U.S. market until now?In this episode, Rick Stewart, CEO of Achieve Life Sciences, shares how cytisinicline is redefining smoking cessation after receiving FDA acceptance for its New Drug Application (NDA)—a major milestone in the fight against nicotine dependence.What we discuss:• FDA acceptance for the cytisinicline New Drug Application (NDA) and what comes next• Why cytisinicline represents a breakthrough in smoking cessation• Commercial readiness...
2025-12-051h 00
Innovating Tomorrow's MedicineSneek Peak: Rick Stewart on Cytisinicline redefining the future of nicotine dependenceWhat if a naturally derived compound used for decades overseas could finally transform smoking cessation in the U.S.?Rick Stewart, CEO of Achieve Life Sciences, just received FDA acceptance for cytisinicline's NDA—a major milestone that could help millions quit smoking.🎙️ Full episode drops December 4In the complete interview, we dive into:• FDA NDA acceptance and what comes next• Commercial readiness and go-to-market strategy• Financial strategy and capital efficiency• Public health impact at scaleSubscribe so you don't miss it.#SneakPeek #Smok...
2025-11-2801 min
Innovating Tomorrow's MedicineSheila Gujrathi on The Spiritual Foundation of Biotech Leadership and The Mirror EffectWhat if the key to biotech success isn't just science and strategy—but self-awareness and spiritual practice?In this episode, Dr. Sheila Gujrathi—biotech entrepreneur, executive, and drug developer with over 25 years of experience—shares insights from her Amazon bestselling book The Mirror Effect, exploring how intentional leadership transforms both business outcomes and organizational culture.What we discuss:• The spiritual foundation of effective biotech leadership• Deal-making and corporate development strategies from building multiple companies• Leading the development and approval of Orencia® and Nulojix®• Building diverse, high-performing teams and the Biotech...
2025-11-211h 24
Innovating Tomorrow's MedicineSneek Peek: Sheila Gujrathi on The Spiritual Foundation of Biotech Leadership and The Mirror EffectWhat if the key to biotech success isn't just science and strategy—but self-awareness and spiritual practice?Dr. Sheila Gujrathi—who led the development of Orencia® and Nulojix®—shares insights from her Amazon bestselling book The Mirror Effect, exploring how intentional leadership transforms both business outcomes and organizational culture.🎙️ Full episode drops November 20In the complete interview, we dive into:The spiritual foundation of effective leadershipDeal-making and corporate development strategiesBuilding the Biotech CEO SisterhoodLeading with authenticity in a science-driven industry
2025-11-1401 min
Innovating Tomorrow's MedicineCancer Precision Medicine with real power: Rick Fultz, AcurionWhat if we could bring the power of precision medicine to more cancer patients, faster—using AI to match patients with the right treatments at the right time?In this episode, Rick Fultz, CEO of Acurion, shares how his company is transforming precision oncology by combining next-generation science with artificial intelligence to deliver personalized cancer care at scale.What we discuss:• The vision behind Acurion and its mission in precision oncology• How AI and machine learning are revolutionizing cancer treatment selection• Moving beyond traditional biomarker approaches to comprehensive patient profilin...
2025-10-3151 min
Innovating Tomorrow's MedicineSneak Peek: Rick Fultz on Cancer Precision Medicine with real powerWhat if AI could match cancer patients with the right treatments faster—bringing precision medicine to more people who need it?Rick Fultz, CEO of Acurion, is using artificial intelligence to transform how we select cancer therapies, moving beyond traditional biomarkers to comprehensive patient profiling.🎙️ Full episode drops October 30In the complete interview, we dive into:How AI is revolutionizing cancer treatment selectionMoving beyond traditional biomarker approachesFundraising and building investor confidenceScaling precision medicineSubscribe so you...
2025-10-2401 min
Behind The GateBehind The Gate - Episode #22 - Jeff Ott with Hillbilly Gran Prix, Champion Ben Gentges and Jimmy Trickett with Tech TipsBehind The Gate #22 brings you insight into the Hillbilly Gran Prix Racing Series! Â Your Behind The Gate hosts, Frank Craven and Josh Hudson, have Jeff Off in studio. Â Jeff is the owner/operator of the Hillbilly Racing Gran Prix. Also in studio with Frank and Josh is Ben Gentges. Â Ben is a 21 year old phenom that has been racing hare scrambels for 17 years. Â He recently won his first pro class championship at the 2024/2025 Hillbilly Gran Prix. Also, straight from Letko Cycles, Jimmy Trickett provides our Tech Tip! It's another fun episode of Behind The...
2025-10-0249 min
Innovating Tomorrow's MedicineCRISPR Meets Duchenne: Scalable, Precise, Disruptive - Courtney Young, MyoGene BioWhat if we could use gene editing to treat Duchenne Muscular Dystrophy—not just manage symptoms, but address the underlying genetic cause in a scalable, precise way?In this episode, Dr. Courtney Young, CEO of MyoGene Bio, shares how her company is using CRISPR technology to transform the treatment landscape for Duchenne Muscular Dystrophy, offering hope to patients and families facing this devastating disease.What we discuss:• The vision behind MyoGene Bio and why Duchenne Muscular Dystrophy• How CRISPR gene editing works and why it's uniquely suited for Duchenne• Scalabil...
2025-09-1225 min
Innovating Tomorrow's MedicineSneak Peek: Courtney Young on CRISPR Meets Duchenne: Scalable, Precise, DisruptiveWhat if gene editing could treat Duchenne Muscular Dystrophy at its genetic root—not just manage symptoms?Dr. Courtney Young, CEO of MyoGene Bio, is using CRISPR to address the underlying cause of Duchenne in a scalable, precise way that could transform rare disease treatment.🎙️ Full episode drops September 11In the complete interview, we dive into:• Why CRISPR is uniquely suited for Duchenne• Scalability, precision, and safety in gene editing• Navigating regulatory pathways• The future of gene therapy for rare diseasesSubscribe so you don't miss...
2025-09-0501 min
Innovating Tomorrow's MedicineLytic Peptides: The Ultimate Cancer Weapon: Stanley Lewis, A28 TherapeuticsWhat if we could destroy cancer cells using a completely novel payload—one that doesn't rely on traditional chemotherapy or even antibody-drug conjugates, but instead uses lytic peptides to obliterate tumors?In this episode, Dr. Stanley Lewis, CEO of A28 Therapeutics, shares how his company is pioneering lytic peptides as a next-generation cancer therapy, offering a fundamentally different approach to killing cancer cells.What we discuss:• The vision behind A28 Therapeutics and the science of lytic peptides• How lytic peptides work differently from traditional cancer payloads• Why this approach could ov...
2025-08-2955 min
Innovating Tomorrow's MedicineSneak Peek: Stanley Lewis on Lytic Peptides - The Ultimate Cancer WeaponWhat if we could destroy cancer cells using a completely novel payload that doesn't rely on traditional chemotherapy or even antibody-drug conjugates?Dr. Stanley Lewis, CEO of A28 Therapeutics, is pioneering lytic peptides as a next-generation cancer therapy—a fundamentally different way to kill tumors.🎙️ Full episode drops August 28In the complete interview, we dive into:• How lytic peptides work differently from traditional payloads• Overcoming resistance mechanisms• The role of AI in peptide design• Building A28 TherapeuticsSubscribe so you don't miss it.#SneakPeek...
2025-08-2201 min
Innovating Tomorrow's MedicineCrystalys Therapeutics launches to transform Rheumatology: James MackayWhat if we could transform the treatment landscape for rheumatologic diseases by taking bold, innovative approaches that go beyond incremental improvements?In this episode, Dr. James Mackay, CEO of Crystalys Therapeutics, shares the vision behind launching a new biotech company focused on rheumatology, combining next-generation science with strategic leadership to address unmet patient needs.What we discuss:• The vision behind Crystalys Therapeutics and why rheumatology• New approaches and innovative strategies in treating rheumatologic diseases• Approach to risk management in early-stage biotech• Fundraising strategies and building investor confidence from day...
2025-08-1452 min
Innovating Tomorrow's MedicineSneak Peek: James Mackay on launch of Crystalys Therapeutics to transform RheumatologyWhat does it take to launch a biotech company with bold, innovative approaches to rheumatologic diseases?Dr. James Mackay, CEO of Crystalys Therapeutics, is bringing next-generation science and strategic leadership to patients who desperately need better treatment options.🎙️ Full episode drops August 14In the complete interview, we dive into:• The vision behind Crystalys Therapeutics• New approaches in treating rheumatologic diseases• Risk management in early-stage biotech• Fundraising and building the right teamSubscribe so you don't miss it.#SneakPeek #Rheumatology #Biotech #AutoimmuneDisease
2025-08-0700 min
Innovating Tomorrow's MedicineInnovating Tomorrow's Medicine: Exploring the Future of Biotech and HealthcareWhat does it take to transform bold ideas into real-world treatments that save lives?Welcome to Innovating Tomorrow's Medicine, a podcast that goes beyond the headlines to explore the strategies, insights, and breakthroughs shaping the future of healthcare and biotechnology.Hosted by Dr. Jeff Trickett—a neuroscientist and biotech strategist—this show features candid conversations with biotech founders, CEOs, researchers, and innovators who are tackling medicine's biggest challenges. From AI-driven diagnostics to gene editing, novel cancer therapies, and precision medicine, each episode delivers substantive discussions about the science, strategy, and leadership driving transformative change.Wh...
2025-07-3100 min
Newlines Institute for Strategy and PolicyThe Complex World of Russian EconomicsIn episode 3 of the Russia in Context series, host Jeff Hawn sits down with Nick Trickett, economy analyst and author, and Yakov Feygin, associate director of the Berggruen Institute. In addition to the modern state of the Russian economy, the trio discusses the evolution of the post-Soviet Russian economy, cyclic trends in its development, and how Russia has reacted to sanctions regimes.
2024-02-1540 min
New Lines Institute for Strategy and Policy | PodcastsThe Complex World of Russian EconomicsIn episode 3 of the Russia in Context series, host Jeff Hawn sits down with Nick Trickett, economy analyst and author, and Yakov Feygin, associate director of the Berggruen Institute. In addition to the modern state of the Russian economy, the trio discusses the evolution of the post-Soviet Russian economy, cyclic trends in its development, and how Russia has reacted to sanctions regimes.
2024-02-1540 min
The Sport SocialKim Ravaillion on all things Firebirds + we learn what DRS in F1 is + A concussion discussionOh how we love sport and luckily for us there was so much on! Here's what we covered this week on the show: Blake Johnston breaking the world record for the longest surf session at a massive 40hrs A school sports night and the iconic Jeff Thomson Round 1 of Suncorp Super Netball with Queensland Firebirds Captain Kim Ravaillion. F1 - specifically, a recap from the race in Jeddah, the reign of Toto, and what on earth does DRS actually mean. Concussion across the various Australian football codes. Do we need a national body to provide guidance on this is...
2023-03-2030 min
Pure Grit - with Paula McGrathAngelique Clark - Pure Grit with Paula McGrathAngelique Clark is an Advanced Sports Dietition , Performance Nutritionist and Sports Physiologist. She is the top of her field.Her clients have been elite athletes like Libby Trickett Olympic Swimmer, Jeff Horn Professional Boxer and Danni Prince Australian Champion Gymnast also celebrity transformations Osher and what a transformation he has had....amazing.Her biggest mission in life is to help uncomplicate nutrition so you can access ultimate performance in your activity and in life. Here she shares her elite secrets and science backed nutrition hacks. This is one beautiful entreprenuer Mum who overcame her insecurities in adolescence...
2021-01-201h 01
West Virginia University MountaineersNeal Brown Press Conference Show Presented by Panhandle Cleaning and Restoration | 11-3-20Hosts Dan Zangrilli and Dale Wolfley dive in to WVU head football coach Neal Brown's weekly press conference, and set the stage for the Mountaineers' big matchup against the Texas Longhorns in Austin this weekend. Linebackers coach Jeff Casteel and Tight Ends coach Travis Trickett also join the program.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
2020-11-0359 min
The Flow Show with Jeff GrossSam Trickett / Partypoker Global Ambassador / Live Poker Earnings of $21,347,558In this episode, Sam Trickett, a Party Poker global ambassador with $21,347,558 of live poker earnings, reflects on the mistakes he made in his poker career. He shares poker lessons that translate to life, how to separate emotions from poker, and why it’s important to take care of your body if you want to perform at your best. Tune in to hear about the happiest day in Sam’s life – and learn what drove him to be successful.
Visit Jeff Gross - The Flow Show or find us on iTunes to subscribe, visit previous episodes, and learn more a...
2019-11-171h 40
The Startup Junkies Podcast160: A Discounted Drink with PurluIn this episode of the Startup Junkies Podcast, Jeff Amerine and Michael Iseman sit down with the creators of the Purlu App, Brad Cardwell and Caitlin Trickett. Purlu showcases food and drink specials for Northwest Arkansas in an app interface that is easy to use. Brad and Caitlin discuss the challenges of communicating with a development team on the other side of the world while sharing the excitement of gaining momentum by partnering with NWA restaurants. Download the Purlu app: https://www.purluapp.com/ Connect with Brad: https://www.linkedin.com/in/brad-cardwell-014a07115/
2019-05-1332 min
Funny Peculiar PodcastEpisode 38: Katie Trickett / International Sideshow, Circus & Variety PerformerThis week I chat to the wonderful Katie Trickett Katie Trickett is a sideshow, circus and variety performer living in the UK. She likes shoes, tattoos, small dogs and cake! Katie has a degree in Clothing Design and Technology and was set for a life in the fashion industry until a magician asked her to cover a show for his wife as an assistant and her passion for magic and performance began. After two years working in illusions and assisting several UK magicians Katie decided to learn her own magic, specialising in creating her own stage acts and...
2019-01-2733 min