Shows
The Conversational Flow - An Official Podcast of KCASWhy Standardization Is Critical in ImmunophenotypingIn episode 28 of “The Conversational Flow”, our hosts, Adam and Brian, discuss why standardization is essential for credible flow cytometry data at scale. They walk through the biggest sources of variability - reagents and lots, sample handling and shipping time, anticoagulants and processing choices (whole blood vs. PBMCs, fresh vs. cryopreserved), instrument setup, and downstream analysis - and explain how each one can create “noise” that masquerades as biology. They note practical realities like weather delays and circadian effects, and why stability studies help define which markers remain trustworthy over time. The conversation also highlights where the field has evolved...
2026-01-1455 minThe Conversational Flow - An Official Podcast of KCASTis the Season for Holiday Lights and Flow CytometryThis episode dives into how scientific understanding evolves over time, using immunology as a case study to highlight how often researchers underestimate what they don’t yet know. Adam and Brian reflect on historical quotes from medicine and science that confidently declared fields “complete,” only to be proven wrong by later discoveries. From there, they discuss how the way scientists name and categorize cells shapes how experiments are designed, interpreted, and compared across labs. Inconsistent terminology—especially around complex T-cell subsets—can quietly undermine reproducibility and collaboration, particularly in CRO and translational research settings. The conversation ultimately reinforces that precision...
2025-12-1448 minThe Conversational Flow - An Official Podcast of KCASBasophils & Breakthroughs: A Deep Dive into Drug HypersensitivityIn this most recent episode of “The Conversational Flow”, Adam and Brian dive into the flow-based Basophil Activation Test (BAT), explaining how it works, why it matters, and how it has evolved since basophils were first identified. They describe how BAT uses markers to assess basophil activation from a simple blood sample - offering a safer, more controlled alternative to in-vivo allergen challenges. The hosts highlight major obstacles to widespread adoption, including large protocol variations among labs across Europe and inconsistencies between commercially available kits, both of which make data hard to compare. They emphasize that BAT provides insights seru...
2025-11-1457 min
The Weekly Bioanalysis - An Official Podcast of KCASConference Season 2025: US, APAC, and European Bioanalysis Trade ShowsIn this episode, hosts Dom and John welcome Jason Hannah, Director of Marketing at KCAS Bio, to discuss the company’s strategy for navigating the 2025 global conference season. With major events like AAPS PharmSci 360 in the U.S. and the European Bioanalysis Forum (EBF) in Barcelona on the horizon, Jason explains how KCAS approaches each with a structured, three-phase plan: pre-show planning, on-site activation, and post-show follow-up. He highlights the differences between large, trade show–focused meetings like AAPS and more intimate, science-driven gatherings like EBF, noting how KCAS Bio tailors its engagement and messaging to fit each audience. The...
2025-10-281h 13The Conversational Flow - An Official Podcast of KCASWhat Happens if You Go with the Flow Too MuchIn episode 25 of "The Conversational Flow" podcast, guest David Leclerc, Director of the Cytometry and Antibody Technology (CAT) Facility at the University of Chicago, joins Dom and John to share his professional journey and insights into the evolving world of flow cytometry. Leclerc reflects on his early struggles during his master’s program in Montreal and how those challenges ultimately led him to a fulfilling career in core facility management and leadership. The discussion transitions to explore microfluidics as a potential future direction for the field, and whether these new technologies truly qualify as flow cytometry, emphasizing that innovations li...
2025-10-141h 07The Conversational Flow - An Official Podcast of KCASConsiderations for Flow Cytometry-based Cell SortingIn this episode, Adam and Brian explored recent advances in cell sorting technology, focusing on image-activated approaches. Unlike traditional flow cytometry, which relies on voltage signals, these systems capture and analyze cell images in real time to guide sorting decisions, enabling new insights such as subcellular localization and cell-to-cell signaling. The hosts emphasized trade-offs between purity, yield, and speed, as well as technical considerations like nozzle size, sample stability, and contamination risks. They also highlighted practical applications for downstream omics, clonal line generation, and cell therapy development, while noting both the challenges and excitement surrounding this high-speed...
2025-09-1457 minThe Conversational Flow - An Official Podcast of KCASFlow Cytometry: Not Just for Peripheral Blood AnymoreIn episode #23 of The Conversational Flow, Adam and Brian tackle the question: When can flow cytometry be applied to non-blood matrices, and what must be considered? Using sputum analysis as a case study, they outline the challenges of clinical trial sample collection, emphasizing the importance of pre-analytical factors like consistency, bias, logistics, and handling. They discuss how panel design, reagent selection, and defining the right cell populations are critical starting points, followed by gating strategies and quality control to ensure reliable data. The hosts stress that flow results in these nontraditional matrices are best suited for binary or threshold-based...
2025-08-1447 minThe Conversational Flow - An Official Podcast of KCASThe Nitty Gritty of Global Harmonization (w/ Special Guest, Karla Moncada)In this episode, the hosts introduce Karla Moncada, who shares her professional journey from Flowcore management to her current role at KCAS, and unveils her new KCAS video series, Karla’s Corner, aimed at fostering year-round conversations within the flow cytometry community. Karla emphasizes the value of personal connections in scientific collaboration and how her career has blended customer service with cutting-edge science. The main topic of the episode focuses on global harmonization in flow cytometry, particularly in phenotyping myeloid-derived suppressor cells (MDSCs) across 23 international labs. The discussion highlights challenges such as inconsistent gating strategies, variations in reagent availability, an...
2025-07-1450 minThe Weekly Bioanalysis - An Official Podcast of KCASBalancing Growth with Employee Experience, Part 2 - Special Guests, Maria Nelson & Julie DeaneIn this episode of “The Weekly Bioanalysis” podcast, our hosts, Dominic Warrino and John Perkins, sit down with two key leaders shaping the company’s future — Maria Nelson, Chief Financial Officer, and Julie Deane, Chief People Officer — to discuss KCAS Bio’s strategy for balancing rapid growth with an exceptional employee experience. Building on the previous conversation with Jeff Goddard, this episode dives deeper into how KCAS Bio has evolved its people operations and operational planning. Julie shares how private equity investment fueled a transformation in talent acquisition, creating a scalable, high-performing recruitment process that attracts thousands of candidates monthly whil...
2025-06-281h 36The Conversational Flow - An Official Podcast of KCASFlow Cytometry & Autoimmunity – A High Affinity Pharmacodynamic MatchIn episode 21 of “The Conversational Flow” podcast, our hosts, Adam and Brian, explore the transformative power of gene therapy, starting things off by highlighting a compelling case involving CRISPR with milestones that once seemed impossible. They dive into the science behind CRISPR’s precise gene-editing capabilities and its potential for rapid, customizable treatments targeting rare and complex genetic mutations. The conversation also touches on the broader landscape of gene therapy delivery mechanisms and how advances are gradually expanding what's possible for more patients. Shifting gears, they critically examine recent vaccine policy developments and express concern about anti-scientific sentiment influencing public...
2025-06-1451 minThe Weekly Bioanalysis - An Official Podcast of KCASBalancing Growth with Employee Experience, Part 1 - Special Guest, Jeff GoddardIn Episode 89 of The Weekly Bioanalysis, hosts Dominic Warrino and John Perkins engage in a compelling conversation with special guest, Jeff Goddard, Senior Vice President of Corporate Development at KCAS Bio. The three delve into KCAS Bio's strategic growth, including the acquisition of France-based Active Biomarkers, which expanded the company's transatlantic presence. Jeff shares insights into the evolving landscape of bioanalytical services and how KCAS Bio is positioning itself to meet the challenges of modern drug development. The discussion also touches on the importance of collaboration and innovation in accelerating therapeutic discoveries.“The Weekly Bioanalysis” is a podc...
2025-05-281h 36The Conversational Flow - An Official Podcast of KCASImpactful Developments Across Oncology and Regulatory ScienceIn this milestone 20th episode of The Conversational Flow, hosts Adam and Brian dive into impactful developments across oncology, regulatory science, and bioanalytical innovation. The episode highlig4 hts a major Keytruda study showing the first significant improvement in head and neck squamous cell carcinoma outcomes in over two decades, the FDA’s pilot integration of generative AI in scientific review processes, and Sanofi’s acquisition of AI-developed bispecific antibodies for autoimmune diseases. The conversation rounds out with thoughtful discussion on data harmonization across multicenter flow cytometry studies and updates on KCAS’s scientific contributions at CYTO and regional events.“The Conversational Flow”...
2025-05-1453 minThe Weekly Bioanalysis - An Official Podcast of KCASReflections on WRIB 2025 in New Orleans - With ALL the Guests!!In Episode 88 of The Weekly Bioanalysis, hosts Dominic Warrino and John Perkins present a special WRIB 2025 recap featuring several KCAS Bio scientists who share firsthand insights from their presentations at the major bioanalytical conference. Dave Ambrose highlights KCAS Bio’s global harmonization of spectral flow cytometry instruments across sites in the U.S., France, and Australia, showcasing the industry’s first off-the-shelf spectral flow panel with impressively tight inter-site CVs. Jessica Pham discusses her work on a VAMS-based PK assay for an anti-malarial monoclonal antibody, designed to enable microsampling in remote regions with high temperature stability. Bryan Parmentier presents a no...
2025-04-281h 13The Conversational Flow - An Official Podcast of KCASBuilding on Backbone Panels: Standardization, Speed, and IntegrationIn the 19th episode of “The Conversational Flow”, our hosts, Brian and Adam, dive into the utility and innovation behind backbone panels in spectral flow cytometry, spotlighting a recent paper from BMS that presents a robust, flexible assay designed for immune monitoring using the Aurora platform. They discuss how backbone panels streamline assay development, enhance reproducibility, and are well-suited for integration with AI-driven gating strategies. The conversation also touches on industry trends shared at WRIB, including the push toward global harmonization of instruments and standards in clinical trials. With insights on panel optimization, autofluorescence extraction, and metadata standardization, the epis...
2025-04-141h 03The Weekly Bioanalysis - An Official Podcast of KCASEvolution of SCIEX’s Partnership with Pharma in Drug Discovery & DevelopmentIn episode 87 of The Weekly Bioanalysis podcast, John Perkins and Dawn Dufield preview the upcoming WRIB conference, where KCAS Bio and Sciex will both have strong representation through scientific presentations, panels, and business development efforts. Special guest, Rahul Baghla of Sciex, discusses the company’s collaboration with KCAS Bio and introduces their high-throughput Echo technology, which uses acoustic ejection to improve speed and reduce carryover in early discovery assays. The conversation explores the evolution of mass spectrometry platforms, highlighting the robustness and sensitivity of Sciex’s 7500+ system and the increasing role of AI in streamlining data analysis. Dawn and John...
2025-03-2850 minThe Conversational Flow - An Official Podcast of KCASFlow Cytometry & Cell Therapy: One Cell Can Make a World of DifferenceIn this engaging episode of the podcast, hosts Brian Wile and Adam Cotty welcome special guests Michael Naso, Hillary Quinn, and Barry Morse from The Therapeutic Innovations Group—a powerhouse team of scientists and biotech veterans with decades of experience across biologics, small molecules, and cell therapy. The conversation dives deep into the guests’ unique career journeys, and their own consulting venture aimed at helping startups and academic teams navigate early-stage biotech development. Along the way, listeners are treated to insider stories, genuine camaraderie, and valuable insights into cutting-edge topics like CAR-T cell analysis, flow cytometry, and the evolving land...
2025-03-141h 08The Weekly Bioanalysis - An Official Podcast of KCASImmunogenicity Discussion w/ Special Guest Cheikh Kane – What is a Lean ADA?During episode 86 of KCAS Bio's "The Weekly Bioanalysis" podcast, our hosts Dom and John are joined by Dr Cheikh Kane, the Vice President of Biopharma Services at KCAS Bio, to discuss immunogenicity. They first define Immunogenicity; what it is and why it is tested, as well as the standard approach for ADA testing before answering the question of "What is a 'Lean' anti-drug antibody (ADA) approach, and when should it be employed?". Dr Kane brings his decades of experience and biopharmaceutical expertise to a very impressive conversation that showcases the many options involved in ADA testing. This is one...
2025-02-281h 17The Conversational Flow - An Official Podcast of KCASFlow Validations and Guidance Document Changes in 2024-2025Episode 17 of The Conversational Flow podcast, hosted by Brian Wile and Adam Cotty, dives into the evolving landscape of flow cytometry networking and regulatory guidance, where they analyze recent FDA biomarker validation guidance, comparing it to existing industry standards like CLSI H62. Our hosts explore the challenges of harmonizing flow cytometry reporting, the role of regulatory clarity, and the potential for standardized data formats to drive the field forward. Packed with insights on professional networking and scientific validation, this most recent episode offers a deep dive into both career development and regulatory trends in flow cytometry.“The Co...
2025-02-1445 minThe Conversational Flow - An Official Podcast of KCASThe Role of Flow in Drug Autoimmune Indication ResearchIn episode 16 of The Conversational Flow podcast, hosts Brian Wile and Adam Cotty are joined by Allie Greenplate and Ayman Rezk to explore “The Role of Flow in Drug Autoimmune Indication Research.” The discussion delves into the surge in pharmaceutical R&D for immune and autoimmune indications, highlighting the influence of oncology treatments in shaping this trend. The guests shed light on how advancements in high-dimensional flow cytometry, particularly with more than 20-color capabilities, have accelerated breakthroughs in this field. They also discuss the cutting-edge frontiers of autoimmune research, from innovative therapies to emerging technologies in development. This episode prov...
2025-01-141h 00The Weekly Bioanalysis - An Official Podcast of KCASSmall Molecule LC-MS Development and Evolving Approach to ADC PayloadsIn episode 84 of “The Weekly Bioanalysis”, our special guest, Bryan Parmentier, joins Dom and John to discuss his background and current role at KCAS Bio, offering insights into the field of small molecule method development. He delves into the typical challenges encountered when working with LC-MS analytes, and how the evolving role of LC-MS continues to shape the industry. Parmentier emphasizes the value of pre-validation in ensuring method robustness and shares lessons learned from developing methods for antibody-drug conjugate (ADC) payloads. He also details the revised KCAS Bio approach for method development of ADC payloads and the associated downstream vali...
2024-12-281h 32The Conversational Flow - An Official Podcast of KCASFantastic Fluorophores and Where to Find Them (w/ Kelly Lundsten)In this exciting 15th episode of The Conversational Flow podcast, titled "Fantastic Fluorophores and Where to Find Them," hosts Brian Wile and Adam Cotty from KCAS Bio are joined by special guest Kelly Lundsten from FluoroFinder. Together, they dive into the fascinating world of spectral flow cytometry, exploring key questions such as whether spectra or brightness is more critical for controls, which traditional fluorophores the field should consider moving away from, and what potential pitfalls new dyes might present for users. They’ll also discuss the operational benefits of adopting newer dyes, including how they can simplify cocktail preparation an...
2024-12-141h 05The Conversational Flow - An Official Podcast of KCASModifying Flow Cytometry Panels: the “Backbone” of Flow CytometryA flow cytometry backbone panel is a set of antibodies that can be used as a starting point for identifying cell types, and then supplemented with additional markers. On the most recent episode of “The Conversational Flow”, our hosts, Brian and Adam, spend some time together as they answer the questions of “What is a backbone panel?”, “What type of changes should be considered for a backbone panel?”, “What are the advantages to backbone panels for translational teams?”, “What should one be careful of when modifying a backbone panel?”, “Should you use a backbone panel for a translational research program?”, and many ot...
2024-11-1450 minThe Weekly Bioanalysis - An Official Podcast of KCASConference Season 2024: KCAS Bio’s Upcoming Exhibitions & PresentationsIt’s conference season! This is a busy, busy time of the year for the entire industry, when everyone comes together from around the world to share, listen and discuss the changes and advancements taking place in the business and science of the pharma and biotech space. During this episode of “The Weekly Bioanalysis”, our hosts, Dom and John, go over all the places – around the world – where the KCAS Bio team will be taking part in exhibitions, panels and presentations. From Europe to Australia and all over the U.S., KCAS Bio will be attending a number of events, co...
2024-10-281h 32The Conversational Flow - An Official Podcast of KCASLow Content Analysis: When a smaller panel is better than a larger oneDuring the most recent episode of “The Conversational Flow” podcast, our hosts Brian and Adam talk about those times when a smaller panel might be desirable over a larger panel. To dive deep into this discussion and really analyze all the angles of these questions, the guys have invited a special guest to join them – Amrutesh Puranik, PhD. Amrutesh is the founder of Bespoke MultiOmics Consultants, and his perspective is very insightful as they answer the questions of “What are the benefits of having a focused biological question and data interpretation plan?”, “Why are small panels recommended for cell sorting?”, “...
2024-10-141h 04The Weekly Bioanalysis - An Official Podcast of KCASGLP-1 Analogue Bioanalysis: The Value of Complimentary TechnologiesAfter such a great response to our recent episode on the topic, our hosts, Dom and John, revisit the topic of GLP-1 Analogue development and the role bioanalysis plays in this relatively new and popular topic. In the words of John, “Everyone else is talking about this; why shouldn’t we?” And wow, do they have a lot to say about it on this second pass at the advances being made in this ever-growing and ever-changing field. The guys talk about the latest developments in the GLP-1 Analogue space, KCAS Bio’s experience with GLP-1 Analogs, options when choosing the righ...
2024-09-281h 09The Conversational Flow - An Official Podcast of KCASHigh Content Analysis: Finding Needles in a Growing HaystackIn the 12th episode of “The Conversational Flow” podcast, Brian and Adam welcome two special guests – Sean Burke of Denovo Software and Ryan Brinkman of Dotmatics – who join them to discuss the answers to a number of specific questions about High Content Analysis: How can we manage and derive insight from higher complexity panels? How can this be standardized? Once standardized, how can the process be automated? Why is more data challenging to deal with? How can we generate meaningful answers from known and unknown antibody combinations? How can this enormous amount of data be standardized? How can this type of...
2024-09-141h 03The Conversational Flow - An Official Podcast of KCASGoing Global with Spectral Flow Cytometry - US, EU and Now AustraliaDuring this special episode of "The Conversational Flow" our hosts, Brian and Adam, welcome two guests: John Bucksath, CEO of KCAS Bio, and Stefan Cross, CEO of Crux Laboratories. These two guests discuss the elements and advantages of their organizations' new partnership between KCAS' US and European locations and Crux's location in Melbourne, Australia. Recent months have seen the three locations (Crux in Melbourne, and KCAS's Philadelphia and Lyon facilities) collaborate with Cytek to globalize the use of KCAS' multiple Cytek Aurora platforms and offer advanced spectral flow cytometry universally to their customers around the world. Learn about all...
2024-08-141h 06
The Weekly Bioanalysis - An Official Podcast of KCASOne & Done Therapies: The Landscape of Gene Therapy for ConditionsThe most recent episode of "The Weekly Bioanalysis" podcast is all about genes today! The topic was originally inspired by an article entitled "The Coming of Age of One-and-Done Therapies" which jumped out to both of our hosts, Dom and John, and had been on the back burner for a while for them to discuss. With KCAS Bio housing entire departments specializing in bioanalysis, and given the recent rise of similar topics in the news, this seemed like the right time for the guys to chat about it.“The Weekly Bioanalysis” is a podcast dedicated to discussing bioa...
2024-07-281h 20The Conversational Flow - An Official Podcast of KCASInstrument Comparison: Some Instruments are More Equal than OthersWhen it comes to flow cytometry instrumentation, there are a number of things that can be different. You may have different types of lasers, you might have a different path for the laser to follow to get to the detector, you can have different actual detectors, different filters in front of those detectors, not to mention the varying sensitivities or levels of power for any of these items. In episode #10 of "The Conversational Flow", Brian and Adam discuss all of these while comparing them and deciding which elements matter the most for your project.“The Conversational Flow” an o...
2024-07-1455 minThe Weekly Bioanalysis - An Official Podcast of KCASOffering Global Services: Latest News from Lyon and MelbourneDom has been globe-trotting lately, and he has come back to report in on his adventures with John, as they discuss our global services here at KCAS Bio. They talk about the updates and the latest news from Lyon and the rollout of our collaboration with Crux Laboratories in Melbourne. Most notable was Dom’s trip to Lyon and some of the excitement he experienced there (spoiler: it involves tear gas!!). Our two hosts also discuss the strategy and growth of both our Lyon site, and the new things happening with our collaboration site in Australia. Lots to cover – shou...
2024-06-281h 22The Conversational Flow - An Official Podcast of KCASBatch Effects, Controls, and Considerations for Longitudinal StudiesLet’s face it - nobody likes batch effects (unless it has to do with cookies, but that’s for another podcast). In episode #9 of “The Conversational Flow”, Brian and Adam talk about Batch Effects which is when you're having changes in the study that are not necessarily related to the scientific variables of the study – and what that might mean you will need to do next. Batch Effects can cause a number of headaches for anyone without experience with them… luckily both of our hosts have a number of years in the lab, and they have seen a thing or two...
2024-06-141h 04The Weekly Bioanalysis - An Official Podcast of KCASNon-GLP Studies from Early PK to Readiness for GLP Tox StudiesDom and John welcome special guests, Habibi Goudarzi and Rochelle Burke to episode #77 of "The Weekly Bioanalysis", where they discuss the progression of bioanalytical needs for non-GLP Studies, from Early PK to readiness for GLP Tox Studies. These specialists from the KCAS Bio team begin with an introduction to all things non-GLP and LC-MS. From there, they discuss the general need for speed and the workflow they have established at KCAS Bio to facilitate rapid turnaround for studies, as well as some of the challenges that can be an obstacle to the speed of studies (issues with tissue analysis...
2024-05-281h 30The Conversational Flow - An Official Podcast of KCASReceptor Occupancy Testing in Clinical TrialsFor episode #8 of “The Conversational Flow” podcast, Brian and Adam spend the time discussing Receptor Occupancy Testing in Clinical Trials. Receptor occupancy (RO) assays are important in clinical trials because they provide valuable information about a drug’s binding characteristics and mechanism of action. Our hosts begin by outlining the general need for accurate RO calculation (per time point, per subject, etc), then they move on to pre-analytical risks (collection, shipment, transit, receipt, etc) and more specifics like staining and preparation process, acquisition and data analysis, harmonization between multiple testing facilities, and interpreting RO data.“The Conversational Flow” an...
2024-05-1445 minThe Conversational Flow - An Official Podcast of KCASThe Current State of Receptor Occupancy ValidationFor episode #7 of “The Conversational Flow”, Brian and Adam invite David Ambrose to join them as they continue their conversation about Receptor Occupancy assays. There are so many unique considerations around an RO assay and with any flow cytometry assay, the precision of that assay is important. Our hosts discuss the biggest differentiators when you're starting to think about an RO assay and how to optimize the development of those assays and why it is so incredibly important to have a full understanding of the instrumentation being used in order to get the process right. “The Conversational Flow” an...
2024-04-151h 00The Weekly Bioanalysis - An Official Podcast of KCASRebranding KCAS Bio: Next Steps to an Integrated FutureCEO of KCAS Bio, John Bucksath, joins Dom and John for a special 75th episode of “The Weekly Bioanalysis” podcast, and he is absolutely delighted to use the special episode to talk about the recent rebrand of KCAS to KCAS Bio! Mr Bucksath and our hosts discuss the reason the rebrand came about, the process our organization took, and some of the initial reactions our team have experienced from our first few outings with the new look and name. Join us as we introduce the new brand and point to it as the first of many steps into the futu...
2024-03-281h 03The Conversational Flow - An Official Podcast of KCASReceptor Occupancy: Deceptively Simple QuestionsThe newest episode of “The Conversational Flow” has Brian and Adam talking about the concepts around Receptor Occupancy and all the deceptively simple questions people often have about them, as well as the important but sometimes difficult answers to those questions. They talk about the biology of receptors and the few different "classes" associated with ROs. At their core, these are complex molecules with complex functions being discussed... and who better to have these complex discussions than our own experts, Brian and Adam?“The Conversational Flow” an official podcast of KCAS Bio, and focuses on the more niche to...
2024-03-1438 minThe Weekly Bioanalysis - An Official Podcast of KCASAddressing the Needs of Rare Diseases: Challenges & TrendsDuring this episode of “The Weekly Bioanalysis”, Dom and John talk about addressing the needs of rare diseases - some challenges and industry trends they’ve watched take place, and they are joined by guest, Lindsay Rutherford, who has her own personal experience with rare disease and how it can impact lives. As a bioanalytical provider, KCAS Bio of course has a unique take on this topic as well, as rare disease has its own challenges in terms of small sample loads, rapid turnaround of samples to get results out to pharma companies, lack of matrix, etc.“The Week...
2024-02-281h 13The Conversational Flow - An Official Podcast of KCASWhat Is Cell Sorting and What Role Does It Play in Bioanalysis?During this newest episode of “The Conversational Flow”, Brian and Adam discuss cell sorting and the pivotal role it plays in molecular biology applications – enabling researchers to isolate specific cell populations from complex mixtures, as well as a number of other benefits. Our hosts dive into the importance of cell sorting, the evolution of the field, and why KCAS Bio is the perfect partner for cell sorting in molecular biology applications. Using the right equipment and expertise for your cell-sorting can help you find and isolate the rare populations that have an outsized impact for your molecular biology analysis.
2024-02-1444 minThe Weekly Bioanalysis - An Official Podcast of KCASThe Parallel Evolution of the Bioanalytical Industry and KCASTo kick off the first episode of “The Weekly Bioanalysis” in 2024, Dom and John unveil some fun new things happening at KCAS, by talking about the parallel evolution of the bioanalytical industry and KCAS. Our hosts go way back – almost to “square one” (discussing “What is bioanalysis?” and “How has bioanalysis changed over the years?”. They take a nice little dip back into history and then and then tie it all back to where we are now and what it means about we are going for the future. We hope you enjoy our announcement as much as you enjoy listening to how w...
2024-01-281h 10The Conversational Flow - An Official Podcast of KCASWhat Makes Spectral Flow so Significant?For the 4th episode of “The Conversational Flow” podcast, Brian and Adam discuss spectral flow; something really near and dear to their hearts. This is a topic both of our hosts have been genuinely interested in since they really became aware of it, at which time they immediately began pushing to bring the instrumentation to KCAS. While they have hinted at it and talked about this topic off and on, even in just the few episodes of the podcast already, they take a significantly deeper dive in this episode and showcase why spectral flow is at the forefront of tech...
2024-01-1446 minThe Weekly Bioanalysis - An Official Podcast of KCASIntroduction to Scientific Advisor Team and Recap of 2023For the final episode of “The Weekly Bioanalysis” in 2023, Dom and John invited KCAS’s scientific advisory team to join them, as we thought that as we are coming to the end of the year, it might be a good opportunity to introduce a few members of the scientific advisory team who may be involved in some greater capacity with the podcast going forward, as the organization grows and expands. Then our hosts just have a chat about reviewing how 2023 went and what they see coming up in 2024 within the pharmaceutical and biopharmaceutical industries – so a look back, a look at...
2023-12-281h 16The Conversational Flow - An Official Podcast of KCASHow do You Validate a Flow Cytometry Assay?There are a number of different guidances for Flow Cytometric Assay Validation, so for episode #3 of “The Conversational Flow” podcast, Brian and Adam go into great detail on how we perform validations at KCAS, and under what context we do so – and why. In this episode, the guys break down the different types of validation and the various levels of qualification related to flow validation, as well as the differences between validation and qualification – which, in and of itself has has gone through an evolution as a concept – and discuss how this all influences how to validate a flow cytometry...
2023-12-1443 minThe Weekly Bioanalysis - An Official Podcast of KCASDrug Development and Where Bioanalytical Fits InDom and John have been doing this for a long time (for over 70 episodes now, to be exact), but they felt it might be a good idea to jump back to the very beginning and discuss the overarching concept of the Drug Development process and where it is that Bioanalysis fits in. This is somewhat of a response to a recent listener request, but we also feel its important every once in a while to refocus and put all of the things we do at KCAS into perspective against the entire pharmaceutical and biotech industry – from large and small mo...
2023-11-281h 17The Conversational Flow - An Official Podcast of KCASHow Sample Collection Impacts Flow CytometryFor our second episode of “The Conversational Flow” podcast, Brian and Adam felt that the best topic to discuss was that of sample collection, sample processing and the important role it plays in Flow Cytometry analysis. This is an often discussed topic – What is the best way to collect and process samples – and it really comes down how you plan to use the samples. When looking at certain assays, fresh samples are needed, whereas with others, frozen samples may not only be acceptable – they may even be preferable. Brian and Adam dive into this episode with all the info you will n...
2023-11-1456 minThe Conversational Flow - An Official Podcast of KCASWhy Does Flow Cytometry Need Its Own Podcast?Flow cytometry is a technique used to detect and measure physical and physiological characteristics of a population of cells or particles. Tens of thousands of cells can be quickly examined and the data gathered is processed by a computer. Uses of flow cytometry can included determination of Cellular characteristics and function, biomarker detection, proliferation, toxicology and diagnosis of health disorders. For our inaugural episode of "The Conversational Flow", Adam and Brian discuss how Flow Cytometry has become so important to the industry and why it warrants getting its very own podcast."The Conversational Flow" an official podcast...
2023-10-1340 minThe Weekly Bioanalysis - An Official Podcast of KCASThe Evolving World of Antibody-Drug Conjugates and How KCAS Can HelpStarting off with a description of Antibody Drug Conjugates (or ADCs, for short), Dom and John dive into this field of the industry and discuss the ways these services have changed over time and even how they've changed recently. They review the role of ADCs in meeting some of the unmet medical needs in oncology and the way they're changing the effectiveness of some of the most modern drugs being developed. The evolution of ADC design for approved medications and indications make it clear that Antibody Drug Conjugates will be a big part of our industry for a long...
2023-08-291h 20The Weekly Bioanalysis - An Official Podcast of KCASMolecular Cell & Gene Therapy, with Special Guest Carrie Vyhlidal, PhDSpecial guest Carrie Vyhlidal, PhD of KCAS joins John and Dom in the 68th episode of "The Weekly Bioanalysis" to discuss the ways molecular cell & gene therapy services has evolved and why their role will likely become more and more important to the world of bioanalytical drug development in the future. They discuss everything from the history of Cell & Gene Therapies and the topic of replicates, to some of the challenges and pitfalls of GLP research for molecular cell & gene therapy specialists."The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related...
2023-06-281h 27The Weekly Bioanalysis - An Official Podcast of KCASRecent Advances in Hybrid LC-MS/MS (w/ guests Dawn Dufield and Barry Jones)Special guests Dawn Duffield, PhD of KCAS and Barry Jones, PhD of Crinetics join John and Dom in the 66th episode of "The Weekly Bioanalysis" to discuss the ways Hybrid LC-MS/MS has advanced in recent years and how the technology has gone from "new" and somewhat obscure to much more mainstream as a leading option for program success within the pharmaceutical and biopharmaceutical industries."The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Every month, KCAS will bring you another 60 minutes (or so...
2023-03-241h 48The Weekly Bioanalysis - An Official Podcast of KCASA Look Back at 2022 While Looking Ahead to 2023 at KCASIt has been an extremely transformative year for KCAS in 2022. As we approach the beginning of 2023, Dom and John take a moment during episode #63 to look back at all the changes and evolutionary growth that has transpired around the organization (and around the world, as we now have multiple European footprints as well as US locations). They go into detail about the opportunities these changes have allowed for our customers throughout 2022, as well as what it now means for the pharma and biopharma industry as we move forward into 2023."The Weekly Bioanalysis" is a podcast dedicated to...
2022-12-291h 26The Weekly Bioanalysis - An Official Podcast of KCASAn Introduction to Active Biomarkers, with Special Guests John Bucksath and Marc EssodaiguiSpecial guests John Bucksath, CEO of KCAS in Olathe, KS and Marc Essodaigui, General Manager of Active Biomarkers in Lyon, France, join Dom and John this week as they introduce our listeners to Active Biomarkers – the most recent acquisition of KCAS in the European space. The gentlemen discuss a brief history of Active Biomarkers, the path to their acquisition by KCAS, and what it now means – for both the organizations as well as their customers and the industry – now that these two CROs have come together to couple their skillsets."The Weekly Bioanalysis" is a podcast dedicated to dis...
2022-11-301h 17The Weekly Bioanalysis - An Official Podcast of KCASThe 2022 Pharma/Biopharma Trade Show & Conference SeasonEvery year, beginning in late August, with the summer over and everyone settling back into a normal routine, the entire industry begins preparing itself for the conference and trade show season. These events serve as a source for new business in some cases, of course, but they also serve as an opportunity for like-minded scientists and industry leaders to discuss their findings and discoveries over the past year and gauge which direction the industry might be going in the year ahead. This episode, Dom and John discuss the 2022 conference season and where you can find KCAS if you want...
2022-10-311h 20The Weekly Bioanalysis - An Official Podcast of KCASClinical Sample Kitting: Personal Touch Drives SuccessClinical Sample Kitting and Sample Storage have played vital roles in the pharmaceutical and Biopharmaceutical industry for decades, but KCAS began offering the services in the early 1990s in response to shortcomings observed in the collection techniques in trials where we were providing bioanalytical support. During episode #60 of "The Weekly Bioanalysis" podcast, John Pirro and John Perkins host two guests from the Clinical Sample Kitting team who discuss the role these services play in the bioanalytical process."The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and...
2022-10-011h 00The Weekly Bioanalysis - An Official Podcast of KCASIntro to John Pirro, His New SSA Role, and What's Next for the LBA TeamFor the 59th episode of KCAS's podcast, Dom and John are excited to welcome a special guest to the show! John Pirro has been a team member for years now at KCAS, but he joins “The Weekly Bioanalysis” this episode to showcase the changes involved in his new SSA (Senior Scientific Advisor) role, and the team talks a bit about what this means for KCAS's clients’ projects – especially our Ligand Binding Assay. So join us in welcoming John into this new role and learn a bit about the fun things that the KCAS LBA has for the future!"The...
2022-08-261h 27The Weekly Bioanalysis - An Official Podcast of KCASThe Evolution of Drug Design and Its Impact on Bioanalysis (Part 2)In this 58th episode of "The Weekly Bioanalysis" podcast, Dom and John wrap up their 2-part series on the Evolution of Bioanalysis, as they dive into the history of their bioanalysis careers by reviewing Drug Design and Development, and how that has effected the things CROs like KCAS do today. They discuss where the pharmaceutical and biopharmaceutical industry has been, and work their from 2010 or so to the modern day lab space - and even a bit on what the future may hold in the space."The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news...
2022-07-291h 27The Weekly Bioanalysis - An Official Podcast of KCASThe Evolution of Drug Design and Its Impact on Bioanalysis (Part 1)During the 57th episode of "The Weekly Bioanalysis" podcast, Dom and John have a chance to dive into their history of their bioanalysis careers by reviewing the evolution of Drug Design and Development, and how that has effected the things CROs like KCAS do today. They discuss where the pharmaceutical and biopharmaceutical industry has been, and work their way through to roughly 2010 or so by the end of this multi-part series (check back soon for the continued episodes as they move their way into the present day)."The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical...
2022-06-241h 18The Weekly Bioanalysis - An Official Podcast of KCASDiscussing Cell & Gene Therapy Services with Jeff Hester, PhDFor the 56th episode of “The Weekly Bioanalysis” podcast, the Senior Director of Cell & Gene Therapy Services at KCAS, Jeff Hester, PhD, joins Dom and John to discuss the growing field of Cell & Gene Therapy. Cell and gene therapies (CGTs) are types of treatment that use cellular or genetic material with the goal of treating a disease or a disorder. Often it can be a combination of cell and gene therapies, which is the case for chimeric antigen receptor T (CAR T) cells. Jeff explains what KCAS has done in putting together a high-quality team of experts offering these serv...
2022-05-251h 14The Weekly Bioanalysis - An Official Podcast of KCASBuilding For the Future: New Investments in KCASEven while many in the industry have pulled back on growth and expansion efforts after COVID's years-long effect on business and supply lines worldwide, KCAS is in a unique position - as a result of many years of sound decision making and customer relationship building - to expand its operations into an all-new facility full of state-of-the-art equipment and technology throughout. During this month's episode of podcast, Dom and John talk a bit about what everyone can expect as they see KCAS move into these beautiful new facilities during the summer of 2022!"The Weekly Bioanalysis" is a...
2022-04-231h 20The Weekly Bioanalysis - An Official Podcast of KCASRenold Capocasale (Vice Chair and Founder of FlowMetric) Joins as Our Guest!Earlier this month, KCAS announced the acquisition of FlowMetric, LLC, a leading provider of flow cytometry and cellular assay R&D services to biotech, pharmaceutical and cell/gene therapy industries. With the KCAS family growing, Dom and John took the opportunity to invite Renold Capocasale, the Vice Chair and Founder of FlowMetric, to join the podcast for episode #54 to discuss what the recent union of the organizations means for KCAS now that the combined companies are positioned to continue growing operations in Kansas City, Doylestown, PA and Milan, Italy."The Weekly Bioanalysis" is a podcast dedicated to...
2022-02-281h 34
The Weekly Bioanalysis - An Official Podcast of KCASWhat Role Can Bioanalysis Play in Your Drug Development Project?For the first episode of “the Weekly Bioanalysis” in 2022 (also the first episode of our “second season” of the podcast), Dom and John speak to a topic that is near and dear to their hearts: The role Bioanalysis plays in your projects. KCAS offers so many services, but as technologies and discoveries within the industry advance, it is important to understand the ways each type of service can help you in the development of your project. The guys start by defining each phase of development (beginning with discovery/preclinical) and they pinpoint the bioanalytical services available within each phase.
2022-01-251h 28The Weekly Bioanalysis - An Official Podcast of KCASSpecial 50th Episode - LIVE, Together, and "Face-to-Face" for the First Time!!It’s an extra special episode of “The Weekly Bioanalysis” as Dom and John celebrate the 50th EPISODE of the official KCAS Podcast by greeting you LIVE in front of the cameras in person for the first time! To watch the video version of the episode, visit this link on KCAS's website: https://kcasbio.com/blog/twb-050As usual, they discuss the news, the industry, and other topics like their recent trip to AAPS in Philadelphia… but for the first time since we began the podcast, they will do it all as they sit right next to one anot...
2021-10-2950 minThe Weekly Bioanalysis - An Official Podcast of KCASAntibody-Drug Conjugates: The Combination of Targeted Delivery + Potent TreatmentThis episode Don and John thought they would talk about something near and dear to our hearts here at KCAS - Antibody-Drug Conjugates. Increasingly we’ve all experienced talk about ADCs everywhere being approved and for various conditions - mostly oncology (drugs used in the treatment of cancer). And of course the point of an ADC is to use the ability of the antibody to deliver an otherwise very toxic drug to the area of interest as safely as possible. KCAS has supported multiple ADC studies both in the Pharmaceutical and Biopharmaceutical devisions, so Dom and John were really ex...
2021-10-261h 36The Weekly Bioanalysis - An Official Podcast of KCASThe Value of a Dedicated Program Management Team at Your CRODom and John often like to feature each of the groups within our industry that contribute to the success of the team, and recently, one of those groups that they were asked about was Program Management. Both of them see first hand the benefit of having a dedicated program management team at a CRO like KCAS, and while we have often showcased others within our organization, it felt like it was time to shine a light on a too often unsung hero of customer relationships. For this episode, Dom and John invite Chris Young, the director of KCAS's Program...
2021-08-041h 24The Weekly Bioanalysis - An Official Podcast of KCASTrends in the Pharma Industry (post-COVID) and What It Means for KCAS2020 had an impact on nearly every industry around the world in 2021, with effects that will likely continue to ripple well into 2022 and possibly the years beyond. Arguably one of the industries that saw the largest shifts related directly to the events of 2020 were the Pharma and Biopharma sectors. From public perception to investor interest, the unprecedented events had a number of impacts on our industries. To celebrate the 40th episode of "The Weekly Bioanalysis", Dom and John are joined by the CEO of KCAS, John Bucksath, to discuss these impacts and specifically the changes we've experienced here at KCAS...
2021-06-261h 13The Weekly Bioanalysis - An Official Podcast of KCASExplaining the Role of Bioanalysis: Questions from a "Beginner"During episode 39 of "The Weekly Bioanalysis", Dom and John are joined by one of our KCAS colleagues, Mallory Jolly. Mallory is our newest Business Development Representatives, and while she has an extensive background within the industry, she found it occasionally difficult to describe the nuances and particulars that set Bioanalysis apart from the rest of the Pharma and Biopharma industry. As she occasionally brought this up in conversations, she found that even some industry veterans and CEOs would admit they felt the same about the role Bioanalysis plays in drug development. Learning this, Mallory approached John and Dom about...
2021-04-281h 27The Weekly Bioanalysis - An Official Podcast of KCASState of the Union on Vaccines: Current Status with Descriptions and ComparisonsThere are SO many conversations being had about Vaccines right now. In fact its difficult to find a social media stream that doesn't include at least one photo of someone's recently stamped vaccine confirmation paperwork. Everyone is asking "Which one did you get?", "When will my final dose take its full effect?", "Are some vaccines 'better' than others?" Dom and John use episode #38 of the podcast to answer some of these questions and discuss the state of the union on all things COVID vaccine as of mid-April, 2021."The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical...
2021-04-261h 10The Weekly Bioanalysis - An Official Podcast of KCASWhat COVID Taught Us About Drug Development Process LimitationsDuring episode 37, Dom and John are joined by Stephanie Pasas-Farmer, Founder and CEO of Adriadne Software, as we look back over the things our industry has learned about the limitations of the Drug Development Process during COVID. Stephanie and John Pirro, Sr Director of LBA Development at KCAS, discuss the importance of managing processes and how the right software plays a role in facilitating."The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Every week, KCAS will bring you another 45-60 minutes of friendly...
2021-04-261h 22The Weekly Bioanalysis - An Official Podcast of KCASTrends in Drug Development and the Impact on Consumer CostsDuring the 36th episode of “The Weekly Bioanalysis”, Dom and John touch on something they really haven't yet throughout the course of our podcast - the impact of trends within the drug development industry on consumer costs. There is a very clear course most drugs take throughout their process, but minor changes in industry trends can affect the final outcomes of those steps - and ultimately the final costs to consumers."The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Every week, KCAS will brin...
2021-04-011h 16The Weekly Bioanalysis - An Official Podcast of KCASChanging Strains and the State of Play for VaccinesOn the heels of vaccine production and distribution over the past month or so, there has been a lot of talk in the news about Covid variants and what this might mean for infection rates, vaccine implications and what might be next in terms of therapies and treatments. Dom and John examine some of these observations during the 35th episode of “The Weekly Bioanalysis” to discuss a number of the variants around the world and what we know so far."The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Phar...
2021-02-181h 17The Weekly Bioanalysis - An Official Podcast of KCASThe Top 10 Manufacturers in the Fight Against COVID-19Ever since the first COVID vaccine was approved a few weeks ago, everyone has been talking about them. As the FDA (U.S. Food and Drug Administration) issues more and more authorizations and vaccination gets underway, Dom and John take some time to discuss the Top 10 current vaccine and therapeutics manufacturers in the fight against COVID."The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Every week, KCAS will bring you another 45-60 minutes of friendly banter between our two finest Senior Scientific Advisors...
2021-01-301h 07The Weekly Bioanalysis - An Official Podcast of KCASA Look Forward at 2021 Drug Development, COVID and Non-COVIDFor episode #33 of the "The Weekly Bioanalysis" podcast, Dom and John look forward to 2021, and make their predictions for drug development in both COVID and Non-COVID realms."The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Every week, KCAS will bring you another 45-60 minutes of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and brief themselves on what they've learned about the Bioanalytical world the past week.The Weekly Bioanalysis is brought to you by...
2021-01-261h 10The Weekly Bioanalysis - An Official Podcast of KCASA 2020 Retrospective: A Look Back on COVID and 2021 PredictionsFor episode #32 of the "The Weekly Bioanalysis" podcast, Dom and John discuss the effect of COVID on 2020 ."The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Every week, KCAS will bring you another 45-60 minutes of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and brief themselves on what they've learned about the Bioanalytical world the past week.The Weekly Bioanalysis is brought to you by KCAS. KCAS is a progressive growing contract research organization of...
2020-12-2859 minThe Weekly Bioanalysis - An Official Podcast of KCASmRNA Vaccines: Their Technology, Their History and How They WorkFor episode #31 of the "The Weekly Bioanalysis" podcast, Dom and John discuss the technology, history and background on mRNA Vaccines."The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Every week, KCAS will bring you another 45-60 minutes of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and brief themselves on what they've learned about the Bioanalytical world the past week.The Weekly Bioanalysis is brought to you by KCAS. KCAS is a progressive growing contract...
2020-12-231h 15The Weekly Bioanalysis - An Official Podcast of KCASA Business Development Take on the Effects of COVID on Pharma and BiopharmaTo celebrate the recording of our 30th episode, Dom and John bring on 2 of the biggest fans of the podcast - both of whom happen to be Business Development Directors for KCAS. They walk us through their impressions of how COVID has impacted their roles and what they see changing over the next few days, weeks and months within the Pharma and Biopharma world."The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Every week, KCAS will bring you another 45-60 minutes of friendly...
2020-12-211h 22The Weekly Bioanalysis - An Official Podcast of KCASA Status Report: The Latest and Greatest on Drug DeliveryThis week Dom and John give us a status update on where the world of pharmaceuticals and biopharmaceuticals are when it comes to drug delivery. They go over a quick history then discuss the various types and where we stand on each. Additionally, they address a few more COVID Vaccine questions that came in after we finished recording the pre-Thanksgiving episode."The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Every week, KCAS will bring you another 45-60 minutes of friendly banter between our...
2020-12-211h 21The Weekly Bioanalysis - An Official Podcast of KCASHERE COME THE VACCINES!! Our BIG 2020 COVID Vaccine and Therapies Round-UpWe've all lived through 2020, We've experienced what it has been like to wonder if there would EVER be an end to the shut-downs, the social distancing, and the wearing of masks. It seemed for months that the idea of a vaccine being made available would never materialize. But the past few weeks have given us renewed hope with a new nearly-approved vaccine or therapeutic announced almost every day! With all this news coming at us so quickly, Dom and John are taking a break from our "regularly-scheduled programming" to give everyone a breakdown of where ALL vaccines are...
2020-12-211h 15The Weekly Bioanalysis - An Official Podcast of KCASA Look Back at the 2010 "Fierce 15" - Where Are They Now?This week Dom and John take a little stroll back in time roughly 10 years to discuss the 2010 "Fierce 15" to revisit what they were up to at the time... and where they are now."The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Every week, KCAS will bring you another 45-60 minutes of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and brief themselves on what they've learned about the Bioanalytical world the past week.The Weekly...
2020-12-211h 11The Weekly Bioanalysis - An Official Podcast of KCASNon-GLP, Non-Clinical Discovery Drug Development (Part 3 of 3: From Discovery to Pre-Clinical)This week Dr. Habibi Goudarzi, Sr Director of Pharmaceutical Discovery at KCAS, and Marsha Luna, Senior Director of Pharmaceutical LC-MS/MS at KCAS join John as we wrap up our three-part series on Discovery, Non-GLP, Non-Clinical Drug Development. This episode, we focus on the way Discovery flows into Pre-Clinical Studies and how KCAS is involved."The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Every week, KCAS will bring you another 45-60 minutes of friendly banter between our two finest Senior Scientific Advisors as...
2020-12-2146 minThe Weekly Bioanalysis - An Official Podcast of KCASOur Silver Anniversary Episode! Here's a Highlight On Our HostsThe Weekly Bioanalysis celebrates our Silver Episode by featuring our hosts! Dom and John describe each of their unique scientific backgrounds and the experiences that led them to KCAS!."The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Every week, KCAS will bring you another 45-60 minutes of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and brief themselves on what they've learned about the Bioanalytical world the past week.The Weekly Bioanalysis is brought to...
2020-12-2153 minThe Weekly Bioanalysis - An Official Podcast of KCASWhat Role Does Bioanalysis Play in the Pharmaceutical and Biopharmaceutical Process? (Part 2 of 4)This week's episode is part 2 of a 4-part series featuring the role Bioanalysis plays in Pharmaceutical and Biopharmaceutical Drug Development."The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Every week, KCAS will bring you another 30 minutes of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and brief themselves on what they've learned about the Bioanalytical world the past week.The Weekly Bioanalysis is brought to you by KCAS. KCAS is a progressive growing contract research...
2020-12-2152 minThe Weekly Bioanalysis - An Official Podcast of KCASNon-GLP, Non-Clinical Discovery Drug Development (Part 2 of 3: LC/MS-MS and Universal Assays)Dom and John continue our three-part series on Discovery, Non-GLP, Non-Clinical Drug Development. This episode, we focus on Discovery LC/MS-MS & Universal Assays."The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Every week, KCAS will bring you another 45-60 minutes of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and brief themselves on what they've learned about the Bioanalytical world the past week.The Weekly Bioanalysis is brought to you by KCAS. KCAS is a...
2020-12-211h 04The Weekly Bioanalysis - An Official Podcast of KCASNon-GLP, Non-Clinical Discovery Drug Development (Part 1 of 3: In-Life Services)Dr. Alfred Botchway, CEO of Attentive Science, joins Dom and John as we kick off a three-part series on Discovery, Non-GLP, Non-Clinical Drug Development. This episode, we focus on In-Life Services and how they have been affected by the 2020 Covid pandemic."The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Every week, KCAS will bring you another 45-60 minutes of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and brief themselves on what they've learned about the Bioanalytical...
2020-12-211h 12The Weekly Bioanalysis - An Official Podcast of KCASThe Impact of COVID on the Drug Development Industry (part 3 of 3)Dom and John wrap up our 3-part series about the effect COVID has had on the Drug Development industry. Our hosts also share their thoughts on the President and FLOTUS's recent COVID-positive announcement, the treatment they are receiving, and much more."The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Every week, KCAS will bring you another 45-60 minutes of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and brief themselves on what they've learned about the Bioanalytical...
2020-12-211h 01The Weekly Bioanalysis - An Official Podcast of KCASThe Impact of COVID on the Drug Development Industry (part 2 of 3)Dom and John continue our 3-part series about the effect COVID has had on the Drug Development industry. Our hosts also share their thoughts on new coronavirus tests, national thoughts and opinions about COVID Vaccines, and much more."The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Every week, KCAS will bring you another 45-60 minutes of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and brief themselves on what they've learned about the Bioanalytical world the past...
2020-12-211h 02The Weekly Bioanalysis - An Official Podcast of KCASThe Impact of COVID on the Drug Development Industry (part 1 of 3)To celebrate our 20th episode, KCAS CEO John Bucksath joins Dom and John to to kick off a 3-part series on the effect COVID has had on the Drug Development industry. Our hosts also share their thoughts on recent college campus outbreaks, advances with COVID Vaccines, and much more."The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Every week, KCAS will bring you another 30 minutes of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and brief themselves...
2020-12-211h 09The Weekly Bioanalysis - An Official Podcast of KCASA Business Review of Drug Development During a PandemicThis week Dom and John do a sort of "business review" of drug development this past quarter or so during a world-wide pandemic."The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Every week, KCAS will bring you another 30 minutes of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and brief themselves on what they've learned about the Bioanalytical world the past week.The Weekly Bioanalysis is brought to you by KCAS. KCAS is a progressive...
2020-12-211h 09The Weekly Bioanalysis - An Official Podcast of KCASThe Role of Dose Formulation in Bioanalytical TestingThis week Dr Amy Mize joins Dom and John to to discuss the role of Dose Formulation in Bioanalytical Testing. Our hosts also share their thoughts on recent CDC guidance on asymptomatic testing, advances with COVID Vaccines, and much more."The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Every week, KCAS will bring you another 30 minutes of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and brief themselves on what they've learned about the Bioanalytical world the...
2020-12-2154 minThe Weekly Bioanalysis - An Official Podcast of KCASReasons for Multiple Trials in Drug Development and GLP (Good Laboratory Practices)During this week's episode, Dom and John discuss the history behind what produced GLP (Good Laboratory Practices) and the long list of reasons why multiple trials and rigorous testing is necessary as part of the Drug Development Process."The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Every week, KCAS will bring you another 30 minutes of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and brief themselves on what they've learned about the Bioanalytical world the past week.
2020-12-2150 minThe Weekly Bioanalysis - An Official Podcast of KCASThe Challenges of Bioanalysis in Non-Routine MatricesDuring this week's episode, Dom and John discuss the challenges of bioanalysis in non-routine matrices."The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Every week, KCAS will bring you another 30 minutes of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and brief themselves on what they've learned about the Bioanalytical world the past week.The Weekly Bioanalysis is brought to you by KCAS. KCAS is a progressive growing contract research organization of well over 100 talented...
2020-12-2150 minThe Weekly Bioanalysis - An Official Podcast of KCASThe Purpose of Validation and How it Gives Confidence in Bioanalytical DataIn this week's episode, Dom and John discuss the purpose of validation and how it gives confidence in bioanalytical data."The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Every week, KCAS will bring you another 30 minutes of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and brief themselves on what they've learned about the Bioanalytical world the past week.The Weekly Bioanalysis is brought to you by KCAS. KCAS is a progressive growing contract research...
2020-12-2157 minThe Weekly Bioanalysis - An Official Podcast of KCASWhat Role Does Bioanalysis Play in the Pharmaceutical and Biopharmaceutical Process? (Part 4 of 4)This week's episode is the final part of a 4-part series featuring the role Bioanalysis plays in Pharmaceutical and Biopharmaceutical Drug Development."The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Every week, KCAS will bring you another 30 minutes of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and brief themselves on what they've learned about the Bioanalytical world the past week.The Weekly Bioanalysis is brought to you by KCAS. KCAS is a progressive growing...
2020-12-2149 minThe Weekly Bioanalysis - An Official Podcast of KCASWhat Role Does Bioanalysis Play in the Pharmaceutical and Biopharmaceutical Process? (Part 3 of 4)This week's episode is part 3 of a 4-part series featuring the role Bioanalysis plays in Pharmaceutical and Biopharmaceutical Drug Development."The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Every week, KCAS will bring you another 30 minutes of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and brief themselves on what they've learned about the Bioanalytical world the past week.The Weekly Bioanalysis is brought to you by KCAS. KCAS is a progressive growing contract research...
2020-12-2150 minThe Weekly Bioanalysis - An Official Podcast of KCASHow an Around-the-Clock CRO Should Continue Work During a HolidayWith 4th of July coming up, Dom and John discuss the way an around-the-clock CRO should go about continuing work during a holiday to avoid any upsets in their client projects."The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Every week, KCAS will bring you another 30 minutes of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and brief themselves on what they've learned about the Bioanalytical world the past week.The Weekly Bioanalysis is brought...
2020-12-2153 minThe Weekly Bioanalysis - An Official Podcast of KCASWhat Role Does Bioanalysis Play in the Pharmaceutical and Biopharmaceutical Process? (Part 1 of 4)This week's episode is part 1 of a 4-part series where Dom and Jon discuss the role Bioanalysis plays in Pharmaceutical and Biopharmaceutical Drug Development."The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Every week, KCAS will bring you another 30 minutes of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and brief themselves on what they've learned about the Bioanalytical world the past week.The Weekly Bioanalysis is brought to you by KCAS. KCAS is a...
2020-12-211h 18The Weekly Bioanalysis - An Official Podcast of KCASWhat is Bioanalysis? (Part 1 of 3): Small Molecule LC-MS/MSThis is the first in a 3-Part Series of "The Weekly Bioanalysis" wherein Dom and John, our hosts (and Bioanalytical specialists at KCAS) answer the question "What is Bioanalysis?""The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Every week, KCAS will bring you another 30 minutes of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and brief themselves on what they've learned about the Bioanalytical world the past week.The Weekly Bioanalysis is brought to you...
2020-12-2155 minThe Weekly Bioanalysis - An Official Podcast of KCASUnsung Heroes of Bioanalysis: A Focus on Bioanalytical Support ServicesThis week's episode features a discussion about the non-bioanalytical groups involved in Bioanalysis and the critical roles they play."The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Every week, KCAS will bring you another 30 minutes of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and brief themselves on what they've learned about the Bioanalytical world the past week.The Weekly Bioanalysis is brought to you by KCAS. KCAS is a progressive growing contract research organization...
2020-12-211h 09The Weekly Bioanalysis - An Official Podcast of KCASWhy Not BOTH? Advantages of Having LBA and LC-MS/MS Under One RoofThis week's episode of "The Weekly Bioanalysis" features a discussion about when it is advantageous to combine Hybrid LC-MS/MS vs Ligand Binding Assays and why it so great to have both under one roof. Dom and John go into detail about when and why using both of these approaches can help projects and studies."The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Every week, KCAS will bring you another 30 minutes of friendly banter between our two finest Senior Scientific Advisors as they...
2020-12-2135 minThe Weekly Bioanalysis - An Official Podcast of KCASWhat is Bioanalysis? (Part 3 of 3): Hybrid LC/MS-MS vs Ligand Binding AssaysThis is the third in our 3-Part Series of "The Weekly Bioanalysis" wherein the specialists at KCAS answer the question "What is Bioanalysis?" This week, Dom and John host their first-ever guests to the podcast to discuss Hybrid LC-MS/MS vs Ligand Binding Assays."The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Every week, KCAS will bring you another 30 minutes of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and brief themselves on what they've learned about t...
2020-12-211h 03The Weekly Bioanalysis - An Official Podcast of KCASWhat is Bioanalysis? (Part 2 of 3): Large Molecules, Ligand Binding Assays and BiomarkersThis is the second in a 3-Part Series of "The Weekly Bioanalysis" wherein the specialists at KCAS answer the question "What is Bioanalysis?" In this week's episode Dom and John discuss Large Molecules, Ligand Binding Assays (LBA) and Biomarkers."The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Every week, KCAS will bring you another 30 minutes of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and brief themselves on what they've learned about the Bioanalytical world the past...
2020-12-2152 minThe Weekly Bioanalysis - An Official Podcast of KCASSo What's Been Going On Lately Thats NOT Related to COVID-19?With all the news lately about COVID, its easy to forget that there ARE other things happening in the world of bio analysis, pharmaceuticals and biopharmaceuticals. The world of cancer treatments, therapeutics and laboratory drug testing has not taken a break just because of a worldwide pandemic. Dom and John break down all the important things happening that are NOT related to COVID-19 right now.The Weekly Bioanalysis is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Every week, KCAS will bring you another 30 minutes of friendly...
2020-12-2141 minThe Weekly Bioanalysis - An Official Podcast of KCASCOVID-19: What in the World Just Happened??To kick off the all-new official podcast of KCAS, Dominic Warrino and John Perkins introduce the reasons why KCAS is starting a podcast and they discuss their take as bioanalytical scientists on what has just happened to the entire world over the past few weeks and months: COVID-19.Welcome to the Weekly Bioanalysis, a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Every week, KCAS will bring you another 20 to 30 minutes of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and brief...
2020-12-2134 min