Shows
Kratom TownParliament-Funkadelic and Kratom Cocktails! | Kratom Town Podcast | Episode 8We discuss seeing George Clinton and Parliament-Funkadelic live and making Kratom Colada cocktails. Hosted by stand-up comics, philosophers, master swordsmen, and kratom enthusiasts, @nickmarmor and Garrett Ballard.Kratom TownIG: KrattownX: kratomtownNick MarmorYoutube: nickmarmorIG: nickmarmorX: MarmorNickGarrett Ballard Insta: thegarrettballard #Kratomcocktails #Parliamentfunkadelic #Kratomtown
2025-07-291h 36
Kratom Science Podcast112. Zachary Louisiana to Ban Kratom w/ Paul SchexnaydreTown officials linked to law enforcement interests want to criminalize kratom consumers in Zachary Louisiana. A hearing may be anywhere form September 5 - 12. Please contact ambre.devirgilio@cityofzachary.org and dmcdavid@cityofzachary.org and please ask them to allow you to roam free with kratom tea in that part of OUR country. The kratom law in Louisiana passed this summer still allowed for municipalities to ban kratom. These laws don't come from a vaccuum - moneyed interests are always involved. They don't care about whether or not it benefits people. Organize with Louisiana kratom advocates by emailing kr8madvocate...
2023-09-0148 minKratom Science112. Zachary Louisiana to Ban Kratom w/ Paul SchexnaydreTown officials linked to law enforcement interests want to criminalize kratom consumers in Zachary Louisiana. A hearing may be anywhere form September 5 – 12. Please contact ambre.devirgilio@cityofzachary.org and dmcdavid@cityofzachary.org and please ask them to allow you to roam free with kratom tea in that part of OUR country. The kratom law in Louisiana passed … 112. Zachary Louisiana to Ban Kratom w/ Paul Schexnaydre Read More »
2023-09-0148 minKratom Science111. Jakub Zientala of European Kratom Alliance ReturnsJakub Zientala is co-founder and Government Relations Manager of the European Kratom Alliance. He has appeared on KSP episodes #82 and #96. In this episode we have an update about regulation of kratom as a “psychomodular” substance in Czech Republic. We also talk about the legal status of kratom in the Netherlands and other European … 111. Jakub Zientala of European Kratom Alliance Returns Read More »
2023-08-1041 minKratom Science Podcast111. Jakub Zientala of European Kratom Alliance ReturnsJakub Zientala is co-founder and Government Relations Manager of the European Kratom Alliance. He has appeared on KSP episodes #82 and #96. In this episode we have an update about regulation of kratom as a "psychomodular" substance in Czech Republic. We also talk about the legal status of kratom in the Netherlands and other European countries. Stick around for the whole episode, as Jakub unveils some exciting news about kratom in Southeast Asia.
European Kratom Alliance eka.eu/
Kratom Science is on Facebook.com/kratomscience, Twitter @kratomscience, TikTok @kr80mscience
Music: Risey, "Memories of Thailand"
Kratom Science...
2023-08-1041 minKratom Science Podcast110. Adam Peak and Leann Pierson Fight for Kratom in LouisianaMy guests this week are Adam Peak and Leann Pierson from Baton Rouge, Louisiana. They co-own Bella Sunrise Smokeshop in Baton Rouge. Recently Adam and Leann gave emotional and informative testimony before Louisiana's Senate and House, as well as in Livingston Parish, to oppose the prohibition of kratom, and in support of regulation bills. Will their help, both proposed kratom ban bills were defeated, as was an ordinance proposal that would have criminalized kratom consumers in Livingston Parish. We talk about Louisiana politics, Adam and Leann's personal experience with kratom, and the issues around running a shop selling items...
2023-06-1549 minKratom Science106. Is Kratom Safe or Unsafe?Brian looks at a news report from Bedford, Texas where a diabetic man ended up in the ICU after long term, heavy kratom use including 8-10 “bottles” per day (presumably extract shots) as well as vaping kratom. Yes kratom vaping is actually a thing, and it apparently damaged his lungs. In comparison to the majority … 106. Is Kratom Safe or Unsafe? Read More »
2023-04-0632 minKratom Science Podcast106. Is Kratom Safe or Unsafe?Brian looks at a news report from Bedford, Texas where a diabetic man ended up in the ICU after long term, heavy kratom use including 8-10 "bottles" per day (presumably extract shots) as well as vaping kratom. Yes kratom vaping is actually a thing, and it apparently damaged his lungs. In comparison to the majority of kratom consumers who use plain leaf kratom, cases like this illustrate the toxicology maxim "The dose makes the poison." Green tea extract causes the majority of herb-induced liver injuries, yet headlines don't speak of overdoses on "green tea" as though it's the same...
2023-04-0632 minKratom Science Podcast105. Unpacking Claims of Kratom-Induced HallucinationsBrian talks about his new article "Kratom and Hallucinations: Examining the Evidence Behind the Claims". It boils down to one case report of a man who hadn't slept for a week, 45 poison control center calls, and 6 mild symptoms unrelated to kratom use out of a 150 user sample. Yet with such sparse evidence, 5.7 million Google search results and even a handful of peer-reviewed papers claim kratom causes hallucinations or psychosis. Plus, a short update on state kratom bills.
Kratom and Hallucinations: The Evidence Behind the Claims https://www.kratomscience.com/2023/03/29/kratom-and-hallucinations-examining-the-evidence-behind-the-claims/
2023 State Kratom Bills https://www.kratomscience.com/2023/01/20/2023...
2023-03-3024 minKratom Science Podcast102. Dr. Cornel Stanciu returns to talk about his new kratom survey"Are you a #kratom user? Consider participating in this ~3 min long anonymous survey and help us better understand kratom: https://survey.az1.qualtrics.com/jfe/form/SV_5dWBqO4QpQ7cTmC?fbclid=IwAR0Rot4KzS93TBeiTSbw45AwrmT-SRFEz6uC04-awTIyJEntgGpD8zA3ALA " - Tweet from Dr. Stanciu
Dr. Cornel Stanciu is an addiction psychiatrist and Assistant Professor of Psychiatry at Dartmouth Geisel School of Medicine, and Director of Addiction Services at New Hampshire Hospital. His new survey on kratom use is anonymous and open to all kratom consumers.
As more people consume doses higher than in traditional...
2023-02-2346 minKratom Science Podcast101. Paul and Fallon Schexnaydre Fight for Kratom in LouisianaPaul Schexnaydre fought in Afghanistan and after coming home says he "lost ten years of my life" to the alcohol, opioids, and methamphetamine he used to self-treat PTSD. He later discovered kratom, quit other substances, and now runs a business called Sacred Rivers Tea Company with his wife, Fallon, who joins him on the podcast today. Paul recently testified on two occasions to the Livingston Parish Ordinance Committee, a group of council members who were discussing a possible kratom ban. At the second meeting, Paul was followed home by police after leaving information with the committee that exposed Sheriff...
2023-02-1638 minKratom Science Podcast100. Kratom News: Livingston Cops Lobby to Make More Criminals, State Bans and KCPA, Will FDA Work with Congress?Livingston Parish, Louisiana council is voting on a kratom ban ordinance tonight jard@lpcgov.com, gtalbert@lpcgov.com, mkeen@lpcgov.com, jwascom@lpcgov.com, esandefur@lpcgov.com, gmcmorris@lpcgov.com, tgirlinghouse@lpcgov.com, rdelatte@lpcgov.com, smack@lpcgov.com
We hit 100 episodes! We're in the middle of legislation season, so there's no time to celebrate. Brian goes through the January 31st ordinance council meeting in Livingston Parish, Louisiana - the Sheriff's weak justification for making criminals out of kratom consumers, and his deputy's fumbling over basic information drives vendor Paul Schexnayder to speak his mind. Council will...
2023-02-0954 minJournal Club with Dr. Jonathan CachatJournal Club #39: Survey of Kratom Consumers with Psychiatric ConditionsDr. Jon Cachat and Brian look at a survey conducted from 2019-2020. The survey found the majority of the 2,296 respondents with psychiatric conditions reported improvement in their condition following the consumption of kratom. Recently published by the American Psychological Association, the survey was authored by five past Kratom Science Podcast guests: Drs. Oliver Grundmann, Kirsten Smith, Darshan Singh, Zach Walsh, and Marc Swogger.
References
Grundmann, O., Veltri, C. A., Morcos, S., Smith, K. E., Singh, D., Corazza, O., Cinosi, E., Martinotti, G., Walsh, Z., &
Swogger, M. T. (2023, January 12). Correlations of Kratom (Mitragyna speciosa Korth.) Use Behavior...
2023-02-0234 minKratom Science97. Livingston Parish Kratom Ban; Sheriff Tied to Rehab Center!!!Supporters of the right to consume kratom are encouraged to attend!!!The Livingston Parish Ordinance Committee meetingThursday January 12, 2023 at 5:00 pmat the Governmental Building20355 Government BlvdLivingston LA 70754in the Livingston Parish Council Chambers.On the Agenda: Discussion of Kratom prohibition ordinance Sources brought to the attention of Kratom Science that Sheriff Jason Ard, who proposed … 97. Livingston Parish Kratom Ban; Sheriff Tied to Rehab Center Read More »
2023-01-1231 minKratom Science Podcast97. Livingston Parish Kratom Ban; Sheriff Tied to Rehab Center!!!Supporters of the right to consume kratom are encouraged to attend!!!
The Livingston Parish Ordinance Committee meeting
Thursday January 12, 2023 at 5:00 pm
at the Governmental Building
20355 Government Blvd
Livingston LA 70754
in the Livingston Parish Council Chambers.
On the Agenda: Discussion of Kratom prohibition ordinance
Sources brought to the attention of Kratom Science that Sheriff Jason Ard, who proposed the kratom prohibition ordinance that his brother Jeff introduced to the council of Livingston Parish, Louisiana, has been receiving campaign contributions since 2013 from Smith Tank and Steel, a construction contractor who sponsors Life House, a Christian drug rehabilitation center with...
2023-01-1231 minKratom Science96. Jakub Zientala of European Kratom Alliance on Kratom in Czech RepublicJakub Zientala calls in from the Netherlands to talk about the pending kratom legislation in the Czech Republic. His organization, the European Kratom Alliance (EKA) along with the Czecho-Slovak Kratom Association (ČSAK), and the progressive Pirate Party is pushing for regulation that would fall outside food and drug laws of the European Union. Kratom, along … 96. Jakub Zientala of European Kratom Alliance on Kratom in Czech Republic Read More »
2023-01-0539 minKratom Science Podcast96. Jakub Zientala of European Kratom Alliance on Kratom in Czech RepublicJakub Zientala calls in from the Netherlands to talk about the pending kratom legislation in the Czech Republic. His organization, the European Kratom Alliance (EKA) along with the Czecho-Slovak Kratom Association (ČSAK), and the progressive Pirate Party is pushing for regulation that would fall outside food and drug laws of the European Union. Kratom, along with cannabis, psilocybin, and some other low risk drugs would be classified as "psychomodular" and regulated for consumption. The pro-kratom groups have an ally in Czech Republic's National Drug Policy Coordinator Jindřich Vobořil, who favors real solution to drugs issues like harm red...
2023-01-0539 minKratom ScienceJournal Club #38: Mitragynine in Kratom Trees in ThailandThailand has recently decriminalized kratom after 79 years of prohibition. In today’s episode of Kratom Science Journal Club, Dr. Cachat and Brian look at a study funded in part by the Thai government that analyzed kratom trees growing in various regions of Thailand. The team measured mitragynine levels, accounting for variables in climate such as … Journal Club #38: Mitragynine in Kratom Trees in Thailand Read More »
2022-12-2930 minJournal Club with Dr. Jonathan CachatJournal Club #38: Mitragynine in Kratom Trees in ThailandThailand has recently decriminalized kratom after 79 years of prohibition. In today's episode of Kratom Science Journal Club, Dr. Cachat and Brian look at a study funded in part by the Thai government that analyzed kratom trees growing in various regions of Thailand. The team measured mitragynine levels, accounting for variables in climate such as light, temperature, humidity, and soil moisture. This information will be used to standardize a kratom product for future agriculture. In years to come, Thailand is set to be be a major exporter of kratom to the west, competing with Indonesia, where 95% of kratom imported into...
2022-12-2930 minKratom Science93. Kratom News for December 2022… Read ‘n’ Rant!Brian flies solo for the December edition of Kratom News, where he reads and rants about the case of the Arkansas man sentenced to 10 years in prison for carrying kratom, another family sues a kratom vendor for wrongful death, police in Louisiana continue to lobby so they can arrest kratom consumers, a wealthy New … 93. Kratom News for December 2022… Read ‘n’ Rant! Read More »
2022-12-0839 minKratom Science Podcast93. Kratom News for December 2022… Read ‘n’ Rant!Brian flies solo for the December edition of Kratom News, where he reads and rants about the case of the Arkansas man sentenced to 10 years in prison for carrying kratom, another family sues a kratom vendor for wrongful death, police in Louisiana continue to lobby so they can arrest kratom consumers, a wealthy New Jersey beach town gets bored and outlaws kratom and Delta-8, and we have an update from Europe about the fight for rational kratom regulation in Czech Republic.
References:
"Arkansas man sentenced to 10 years for “trafficking” kratom" https://www.kratomscience.com/2022/11/21/arkansas-man-sentenced-to-10-years-for-trafficking-kratom/
"Flor...
2022-12-0839 minKratom Science92. Kratom News for November 2022Brian and Kailee talk about the results of the state marijuana and psychedelics referendums from Tuesday’s election, a wrongful death lawsuit against kratom companies and the American Kratom Association in Georgia, a death in Transylvania County, North Carolina attributed to suboxone mixed with vaped kratom, a drug company is undergoing human clinical trials for a … 92. Kratom News for November 2022 Read More »
2022-11-1146 minKratom Science Podcast92. Kratom News for November 2022Brian and Kailee talk about the results of the state marijuana and psychedelics referendums from Tuesday's election, a wrongful death lawsuit against kratom companies and the American Kratom Association in Georgia, a death in Transylvania County, North Carolina attributed to suboxone mixed with vaped kratom, a drug company is undergoing human clinical trials for a mitragynine based drug, and another Louisiana parish bans kratom after police lobbying.
REFERENCES:
“Live 2022 Marijuana Election Results” https://www.marijuanamoment.net/live-2022-marijuana-election-results/
“Lawsuit Slams Kratom Industry; Antihistamine Combined with Kratom Extract May Have Caused Death” https://www.kratomscience.com/2022/11/04/lawsuit-slams-kratom-industry-antihistamine-combined-with-kratom-extract-may-have-caused-death/
“Everything...
2022-11-1146 minJournal Club with Dr. Jonathan CachatJournal Club #37: Kratom and Diabetes Study from ThailandDr. Jon starts off talking about the art show that took place in October 2022 at the new Cannabis Museum in Athens Ohio. Then we cover a study out of Thailand on kratom's effects on alpha-glucosidase and lipase, enzymes that are inhibited by medications for the treatment of diabetes. We see how kratom and mitragynine compare to standard prescription medications, and talk about the traditional use and possible advantages and disadvantages of developing mitragynine into a diabetes treatment drug in the future.
Sign up for the Cannabis Museum's email list at https://www.cannabismuseum.com and check out reddit...
2022-10-2733 minKratom Science Podcast90. Kratom News for October 2022Kailee joins Brian to cover kratom and cannabis news for the past month. This month: Biden pardons thousands convicted of simple possession of weed, Michigan has a bill regulating kratom, a Welsh man can't believe kratom importation is illegal in the UK, lab testing will be required for kratom exports from Thailand, and Kratom Science asks whether a 7-hydroxymitragynine-based drug is a good idea.
We also cover Mike "The Kratom Guy" Overstreet who went to Boston's "methadone mile" (aka Mass and Cass) to hand out care packages to homeless people living there, including kratom. Check out Mike's...
2022-10-1335 minKratom Science90. Kratom News for October 2022Kailee joins Brian to cover kratom and cannabis news for the past month. This month: Biden pardons thousands convicted of simple possession of weed, Michigan has a bill regulating kratom, a Welsh man can’t believe kratom importation is illegal in the UK, lab testing will be required for kratom exports from Thailand, and Kratom Science … 90. Kratom News for October 2022 Read More »
2022-10-1335 minKratom Science Podcast89. Journalist Joanna Bernstein on Kratom as Harm Reduction and M.A.T.Joanna Bernstein is a writer originally from Pittsburgh who now resides in Oregon. In 2014 Joanna had a painful bacterial infection that started her on opiates. She eventually developed an addiction and wrote about her experience with recovery in a "3/4 house" in Pittsburgh's Carrick neighborhood. Later she would nearly relapse after being denied pain medication for Stage 4 endometriosis. That's when Joanna discovered kratom.
We also talk about Oregon's Measure 110 that decriminalized possession of small amounts of any illicit drug in the state, and directed funds from Oregon's legal recreational cannabis to expanded addiction treatment. We talk about kratom...
2022-10-0653 minKratom Science88. Kratom News for September 2022Kailee joins Brian to look at the latest kratom news. This month we look at an investigative report asking questions about academic freedom at University of Florida that directly affected kratom scientists, past podcast guest Oliver Grundmann and Christopher McCurdy. Kratom regulations preventing sales to minors pass Pennsylvania House. A kratom consumer protection act is … 88. Kratom News for September 2022 Read More »
2022-09-1541 minKratom Science Podcast88. Kratom News for September 2022Kailee joins Brian to look at the latest kratom news. This month we look at an investigative report asking questions about academic freedom at University of Florida that directly affected kratom scientists, past podcast guest Oliver Grundmann and Christopher McCurdy. Kratom regulations preventing sales to minors pass Pennsylvania House. A kratom consumer protection act is vetoed by the Missouri governor based on false information. Kratom sales are regulated in Thailand but banned in a Louisiana parish.
References
"Inside the Academic-Freedom Crisis That Roiled Florida’s Flagship", Sept 6 2022, The Chronicle. https://www.chronicle.com/article/inside-the-academic-freedom-crisis-that-roiled-floridas-flagship"Kratom is...
2022-09-1541 minJournal Club with Dr. Jonathan CachatJournal Club #35: Feeding Kratom to GoatsDr. Jon and Brian explore a study out of Thailand where goats meat goats ate feed supplemented with dried kratom leaves. What effect did this have on the goats body weight, cholesterol, blood, and feed conversion ratio? Even if it does work, will farmers be able to afford kratom as a feed supplement, given the newly legal market in Thailand?
Also we look at a case of serotonin syndrome after a 63 year old man on multiple medications introduced kratom without consulting his doctor. Then we talk about Tom Segura and kratom.
References
Chanjula, P...
2022-08-2544 minKratom Science87. Kratom News for August 2022Kailee joins Brian for this month’s kratom news. Florida Drug Policy Council considers a kratom ban in the state. A Florida car accident involving a passed out man with a needle in his pocket is blamed on kratom. Big cannabis news: Bill for federal decriminalization of cannabis introduced. WNBA athlete Brittney Griner sentenced to 9 … 87. Kratom News for August 2022 Read More »
2022-08-1151 minKratom Science Podcast87. Kratom News for August 2022Kailee joins Brian for this month's kratom news. Florida Drug Policy Council considers a kratom ban in the state. A Florida car accident involving a passed out man with a needle in his pocket is blamed on kratom. Big cannabis news: Bill for federal decriminalization of cannabis introduced. WNBA athlete Brittney Griner sentenced to 9 years in Russia for 0.7 grams of vape oil. Study finds association between more potent weed and CUD. DEA sued for access to psychedelics for terminal patients.
References"Drug Policy Council Considers Kratom Ban" https://thefloridachannel.org/videos/capitol-update-extended-drug-policy-council-considers-kratom-ban/"Police: Kids jump from moving car...
2022-08-1151 minKratom Science Podcast86. Dr. Walt Prozialeck Returns to talk about Lead (Pb) in KratomWalt Prozialeck returns to discuss his new article published in the journal Toxics, “Public Health Implications and Possible Sources of Lead (Pb) as a Contaminant of Poorly Regulated Kratom Products in the United States”. We talk about the dangers of high levels of Pb exposure, how even moderate doses in some products can cause toxicity over time, how Pb can compound in levels commonly found in some foods, how this effects children and pregnant people, where the Pb is coming from, how side effects in some case reports listed as "kratom-induced" are very similar to side-effects of lead toxicity, and...
2022-08-041h 00
Kratom ScienceSpecial Announcement: NIDA Seeks Kratom Consumers for Massive StudyTo enroll in the study, see: https://enroll.drugabuse.gov/kratom-nida/ On July 20, 2022 the National Institute on Drug Abuse rolled out a massive nationwide study. NIDA is looking for regular kratom consumers to participate. It’s not just a survey: the research team including past Kratom Science Podcast guest Dr. Kirsten Smith will allow participants, via an app, … Special Announcement: NIDA Seeks Kratom Consumers for Massive Study Read More »
2022-07-2109 minKratom Science Podcast85. Kratom News, July 2022Kailee joins Brian to discuss the latest in kratom legal, international, and science news for July 2022.
Articles discussed in this episode:
PA House passes bill banning sale of Kratom to minors https://www.wkbn.com/news/pennsylvania/pa-house-passes-bill-banning-sale-of-kratom-to-minors/Online kratom sales okayed by [Thailand’s] House https://www.bangkokpost.com/thailand/general/2337463/online-kratom-sales-okayed-by-houseBuddhist monks banned from using cannabis, except as medicine https://www.nationmultimedia.com/in-focus/40017260“Kratom use as more than a self-treatment” https://www.tandfonline.com/eprint/BWUQUPBFTI2DKR2MKNDC/full?target=10.1080/00952990.2022.2083967
House Committee Leaders Tackle Marijuana Research, Kratom, Impaired Driving And More In New Spendi...
2022-07-1446 minKratom Science85. Kratom News, July 2022Kailee joins Brian to discuss the latest in kratom legal, international, and science news for July 2022. Articles discussed in this episode: PA House passes bill banning sale of Kratom to minors https://www.wkbn.com/news/pennsylvania/pa-house-passes-bill-banning-sale-of-kratom-to-minors/ Online kratom sales okayed by [Thailand’s] House https://www.bangkokpost.com/thailand/general/2337463/online-kratom-sales-okayed-by-house Buddhist monks banned from using cannabis, except as medicine https://www.nationmultimedia.com/in-focus/40017260 “Kratom use as more … 85. Kratom News, July 2022 Read More »
2022-07-1446 minJournal Club with Dr. Jonathan CachatJournal Club #33: Kratom Scientists Pen Letter Questioning Case Report ReviewDr. Cachat and Brian look at a letter (Smith et al, 2022) authored by former Kratom Science Podcast guests Dr. Kirsten Smith, Dr. Oliver Grundmann, Dr. Chris McCurdy, Dr. Darshan Singh, and other experts in the kratom field. The letter questions a systematic review (Broyan et al, 2022) of kratom case reports that offers buprenorphine as a solution to "kratom use disorder". Kratom-related case reports typically originate with patients showing up to emergency rooms and physicians' offices with symptoms. In these case reports, kratom product samples are rarely if ever tested for adulterants or contamination. The strength of the kratom product...
2022-06-3036 minKratom ScienceJournal Club #33: Kratom Scientists Pen Letter Questioning Case Report ReviewDr. Cachat and Brian look at a letter (Smith et al, 2022) authored by former Kratom Science Podcast guests Dr. Kirsten Smith, Dr. Oliver Grundmann, Dr. Chris McCurdy, Dr. Darshan Singh, and other experts in the kratom field. The letter questions a systematic review (Broyan et al, 2022) of kratom case reports that offers buprenorphine … Journal Club #33: Kratom Scientists Pen Letter Questioning Case Report Review Read More »
2022-06-3036 minKratom Science84. Kratom Vendors’ Association Founder Stacey LloydStacey Lloyd is a microbiologist and GMP complaince specialist. She founded the Kratom Vendors Association to help kratom vendors comply with Good Manufacturing Practices. In an unregulated kratom world, the need for quality control for a psychoactive substance is essential for the future of a legal, regulated, and legitimate kratom market. We talk about what … 84. Kratom Vendors’ Association Founder Stacey Lloyd Read More »
2022-06-0235 minKratom Science Podcast84. Kratom Vendors’ Association Founder Stacey LloydStacey Lloyd is a microbiologist and GMP complaince specialist. She founded the Kratom Vendors Association to help kratom vendors comply with Good Manufacturing Practices. In an unregulated kratom world, the need for quality control for a psychoactive substance is essential for the future of a legal, regulated, and legitimate kratom market.
We talk about what vendors can expect with a membership in the Kratom Vendors Association, what it takes to be GMP complaint, and why quality control is so important for companies selling a consumable product.
https://www.kratomvendorsassociation.com/
@kratomva
Kratom Science...
2022-06-0235 minKratom Science Podcast83. Quality Compliance Expert Jennifer Bruce on Kratom Vendors and GMPJennifer Bruce has "20+ years of industry experience in establishing and implementing quality systems for drugs, OTCs, biologics, dietary supplements and cosmetics from early phase development through commercialization" (from her LinkedIn). She became disillusioned with the pharmaceutical industry, and in 2019 discovered the need for quality assurance in the kratom industry. We talk about why it's important for kratom vendors to follow Good Manufacturing Practices (GMP), how vendors could be shut down by the FDA, why all of this vital to both the quality of the kratom products and the health of the customers who consume them, and why the future...
2022-05-1959 minKratom Science Podcast82. Jakub Zientala of the European Kratom AllianceJakub Zientala, originally from Poland and residing in the Netherlands, calls himself a European at heart and soul. He holds degrees in European and International Law and public policy, and he curently serves as EU and Government relations manager for the newly formed European Kratom Alliance. Kratom is already banned in many major European countries such as the United Kingdom, France, and Italy. Where kratom is legal, it exists mostly in a grey market where kratom can only be sold with the label "Not for human consumption". The EKA exists to fight for Europeans’ right to consume kratom safely....
2022-05-0552 minJournal Club with Dr. Jonathan CachatJournal Club #31: A Kratom Guide for Healthcare ProvidersPerhaps the most important paper Dr. Jon and Brian have covered so far, "Understanding Kratom: A Guide for Healthcare Providers" is a comprehensive introduction to kratom for those who provide direct care to kratom consumers, such as physicians or mental health specialists. In this paper spearheaded by past Kratom Science Podcast guest, Dr. Marc Swogger, reasons are listed for why people use kratom, what the possible risks and side effects are, and the damaging effects of drug hysteria and over-emphases in the medical literature on rare adverse events. Physicians then given recommendations for best practices, and urged to foster...
2022-04-2842 minKratom ScienceJournal Club #31: A Kratom Guide for Healthcare ProvidersPerhaps the most important paper Dr. Jon and Brian have covered so far, “Understanding Kratom: A Guide for Healthcare Providers” is a comprehensive introduction to kratom for those who provide direct care to kratom consumers, such as physicians or mental health specialists. In this paper spearheaded by past Kratom Science Podcast guest, Dr. Marc Swogger, … Journal Club #31: A Kratom Guide for Healthcare Providers Read More »
2022-04-2842 minKratom Science80. Everything Kratom Podcast Host JamieJamie is the host of Everything Kratom Podcast that started in the fall of 2021. The podcast features shorter episodes about different strains of kratom and Jamie’s thoughts on kratom related issues, but also longer episodes with conversations with guests. We talk about why he started the podcast, why there should be more podcasts with … 80. Everything Kratom Podcast Host Jamie Read More »
2022-04-1452 minKratom Science Podcast80. Everything Kratom Podcast Host JamieJamie is the host of Everything Kratom Podcast that started in the fall of 2021. The podcast features shorter episodes about different strains of kratom and Jamie's thoughts on kratom related issues, but also longer episodes with conversations with guests. We talk about why he started the podcast, why there should be more podcasts with our own unique formats, kratom deaths and mourning parents, his own brothers opioid addiction and terrible death, how kratom helped him deal with mild Tourette's Syndrome and helps with motivation, and why he thinks kratom and blue lotus are like peanut butter and jelly.
2022-04-1452 minKratom Science Podcast79. Writer Morgan Godvin on Kratom and Life After IncarcerationMorgan Godvin was a heroin user for five years before being convicted and sentenced to five years in prison on federal "delivery resulting in death" charges after a close friend died of an overdose. Morgan began writing in prison and published her first piece while still behind bars. Upon being released to a halfway house in 2018, she enrolled in university, and graduated Summa Cum Laude in 2021. Morgan now serves as engagement editor for JSTOR Daily's American Prison Newspapers. She serves on the boards of Oregon’s Alcohol and Drug Policy Commission, the Measure 110 Oversight and Accountability Council, and the Mu...
2022-04-0749 minKratom Science Podcast78. Journalist Anthony Roberts: Working on A Leaf of Faith, FOIA’ing the DEA and FDA, and Kratom as NDIAnthony Roberts is a journalist, author of two books on steroids, and and an expert in the field of performance enhancing drugs, dietary supplements, and physical training. He researched interview subjects for the 2018 Chris Bell documentary A Leaf of Faith. We talk about making the movie, grieving parents who target drugs for banning, what he found on former kratom opponent Daniel Fabricant while researching for the movie, the kratom import alert, kratom and New Dietary Ingredient status, why the Natural Products Association wanted to ban kratom, and the documents he dug up on kratom from the FDA and DEA...
2022-03-241h 02Kratom Science Podcast77. Susan Ash, Founder of the American Kratom Association, Part 2UPDATE: INTRO ADDED.we wanted to clarify that we support the AKA's lobbying efforts. In Part 2 (see Episode 76 for Part 1), discuss Susan Ash's exit from the AKA, the motivations behind it, and her response to the allegations against her. We'll also get into the importance of a media campaign in expanding kratom knowledge, what happened to the other kratom organizations, what Indonesian kratom farmers are facing, why everyone should lobby your representatives and engage with media without asking, and how to do it properly.
References:
americankratom.org/donateKratom Lobbying Guide https://www.kratomscience.com/wp-content/uploads/2022/03...
2022-03-171h 09Kratom Science Podcast76. Susan Ash, Founder of the American Kratom Association, Part 1Susan Ash discovered kratom in 2010 after suffering from the effects of Lyme Disease, which she believes she contracted spending years in the forest as part of her education in environmental and forest preservation work. A few years later, it was apparent kratom consumers needed an advocacy organization as some states had banned the plant based on its association with new synthetic drugs. Along with her colleagues Paul Kemp and Sebastian Guthery, she started the American Kratom Association. In 2016, the nonprofit organization grew exponentially, and led thousands of citizens to push back on the Drug Enforcement Administration, who would reverse...
2022-03-101h 02Journal Club with Dr. Jonathan Cachat**REPOST*** Journal Club #29: Kratom Toxicity and Medicolegal Issues, Cannabis MuseumREPOST info: Yesterday I accidentally posted last week's episode with this week's information. I corrected this mistake 45 minutes after posting. Since the change is reflected on some listening apps and not others, I'm posting the episode again. Sorry!
For #29 of Kratom Science Journal Club, JC and Brian look at a 2019 report on toxicological events having to do with mitragynine. Does mitragynine increase the effects of other drugs? How toxic is kratom on its own? Other alkaloids have commonly been counted as mitragynine, so what are the ramifications? All this and other “medicolegal” issues.
Plus, we talk...
2022-02-2549 minJournal Club with Dr. Jonathan CachatJournal Club #29: Kratom Toxicity and Medicolegal Issues, and the Cannabis MuseumFor #29 of Kratom Science Journal Club, JC and Brian look at a 2019 report on toxicological events having to do with mitragynine. Does mitragynine increase the effects of other drugs? How toxic is kratom on its own? Other alkaloids have commonly been counted as mitragynine, so what are the ramifications? All this and other "medicolegal" issues.
Plus, we talk about the Cannabis Museum in Athens Ohio. When will it open? Probably not on 4/20, but close enough.
References
Papsun, D. M., Chan-Hosokawa, A., Friederich, L., Brower, J., Graf, K., & Logan, B. (2019). The Trouble With Kratom: Analytical...
2022-02-2431 minKratom Science74. State Kratom Legislation Update 2022Please refer to this post on the latest information (as of 2/15/2022 on all the state kratom bills. https://www.kratomscience.com/2022/02/07/february-2022-update-on-state-kratom-bills-whos-regulating-whos-banning/ Please contact your state representatives using this link https://myreps.datamade.us/ Updates on state bills in Arizona, Colorado, Florida, Hawaii, Illinois, Kansas, Kentucky, Mississippi, Missouri, New Hampshire, New York, Ohio, Oregon, Virginia, Washington, and Wisconsin. Kratom Science is … 74. State Kratom Legislation Update 2022 Read More »
2022-02-1731 minKratom Science Podcast74. State Kratom Legislation Update 2022Please refer to this post on the latest information (as of 2/15/2022 on all the state kratom bills. https://www.kratomscience.com/2022/02/07/february-2022-update-on-state-kratom-bills-whos-regulating-whos-banning/
Please contact your state representatives using this link https://myreps.datamade.us/
Updates on state bills in Arizona, Colorado, Florida, Hawaii, Illinois, Kansas, Kentucky, Mississippi, Missouri, New Hampshire, New York, Ohio, Oregon, Virginia, Washington, and Wisconsin.
Kratom Science is on Facebook.com/kratomscience and Twitter @kratomscience
Music: Risey, "Memories of Thailand"
Kratom Science Podcast is written and produced by Brian Gallagher for KratomScience.com
So far we don't do advertising...
2022-02-1731 minKratom Science Podcast73. Working with ENCOD and 14 years of Successful Kratom Use with Baylen GreeverBaylen Greever grew up in Memphis, Tennessee. His family moved to Belgium during his high school years. He later got involved with the European Coalition for Just and Effective Drug Policy (ENCOD) and introduced kratom to its founder, the late Joep Ooman. Baylen worked in particular with Friends of the Coca Leaf, to provide education and advocate for policy about coca in plant for (vs. the extract, cocaine). He went with the group to New York to protest outside a UN conference on drug policy where he handed out coca leaves with Bolivian nationals. Baylen now lives in Washington...
2022-02-1037 minKratom Science Podcast71. Marcelle Morfin on Chronic Pain and Kratom AdvocacyMarcelle Morfin got a back injury while serving in the Army in 2006, and that was the beginning of her chronic pain journey. She was later diagnosed with degenerative disk disease, osteoarthritis, fibromyalgia, IBS, and cervical stenosis with myelopathy. She had been prescribed opioid pain medication, but had an aversion to taking pills. In 2017, after contemplating suicide, she discovered kratom which she calls a huge blessing.
After this episode posted, Marcelle reached out and wanted to clarify two things:
"At the ER they gave me Toradol not tramadol. The first is an anti-inflammatory, the one I said is...
2022-01-2045 min
Kratom Science Podcast69. Dr. Christopher McCurdy and Dr. Brian Pearson on the Future of KratomDr. Chris McCurdy is a medicinal chemist who has done groundbreaking research on kratom since 2004, starting at the University of Mississippi. In 2017 Dr. McCurdy moved to the University of Florida College of Pharmacy where he continues his research today with an expert team of pharmacologists, unlocking the function of kratom's many alkaloids and how they interact with our metabolism and brains. Dr. Brian Pearson is a horticulturalist, also at University of Florida, who studies kratom and other medicinal plants, as well as food, landscape, and ornamental plants. Dr. McCurdy talks about his venture into kratom science. Dr. Pearson talks...
2022-01-061h 02Kratom Science Podcast68. Dirk Netter, Author of Kratom: Ethnobotany, Application, and CultureDirk Netter from Germany is the author of one of the only German language books on kratom called Kratom: Ethnobotany, Application, and Culture. As a student at Phillips University in Marburg, Germany he formed the Student Association for Interdisciplinary Psychedelic Research. Dirk Netter has active in the formation of a European kratom alliance to advocate for legality and sensible policy in Europe. We talk about the traditional use and the first European colonialists who classified kratom, safe use, smoking kratom paste (not recommended0, Dirk's debate with the Cleveland Clinic who claimed kratom has "caused death", the WHO decision not...
2021-12-1645 minKratom Science68. Dirk Netter, Author of Kratom: Ethnobotany, Application, and CultureDirk Netter from Germany is the author of one of the only German language books on kratom called Kratom: Ethnobotany, Application, and Culture. As a student at Phillips University in Marburg, Germany he formed the Student Association for Interdisciplinary Psychedelic Research. Dirk Netter has active in the formation of a European kratom alliance to advocate … 68. Dirk Netter, Author of Kratom: Ethnobotany, Application, and Culture Read More »
2021-12-1645 minKratom Science Podcast66. Pascal Tanguay, Drug Policy Expert Talks About Kratom in ThailandKratom Science is very grateful to bring you this interview with Pascal Tanguay. For 20 years, Pascal has been working on harm reduction policies in Southeast Asia and in Thailand where he lives. Pascal is a bottomless well of knowledge on the history of drug policy and kratom. He's worked with the International Drug Policy Consortium and Asian Harm Reduction Network and as a private consultant. We talk about all that, the World Health Organization's stance on kratom, Thailand's recent decriminalisation of kratom, consumer protection laws in the US, and more.
Articles referenced in this episode:
Charoenratana...
2021-12-021h 28Kratom Science66. Pascal Tanguay, Drug Policy Expert Talks About Kratom in ThailandKratom Science is very grateful to bring you this interview with Pascal Tanguay. For 20 years, Pascal has been working on harm reduction policies in Southeast Asia and in Thailand where he lives. Pascal is a bottomless well of knowledge on the history of drug policy and kratom. He’s worked with the International Drug Policy … 66. Pascal Tanguay, Drug Policy Expert Talks About Kratom in Thailand Read More »
2021-12-021h 28Journal Club with Dr. Jonathan CachatJournal Club #27: Does Kratom Kill…E-coli and Streptococcus Pneumoniae?Spoiler alert: kinda, but its more the quercetin in kratom, which is available in many food plants and as a dietary supplement on its own.
This study comes to us from a team at Universitas Nahdlatul Ulama Surabaya (UNUSA) in Surabaya, Indonesia, on the island of Java, south of the island of Kalimantan, where most of the kratom sold in the United States is grown. In this in vitro study, researchers applied a methanol extract of kratom to analogues of e-coli and Streptococcus pneumoniae, a bacteria that causes pneumonia, meningitis, and sepsis. The kratom extract has been...
2021-11-2534 minKratom Science64. Veterans Day Special: A Look Back on Four Veterans Who Told Us Their Kratom StoriesNovember 11, 2021 is Veterans Day! We take a look back at four veterans of the United States military who had a kratom story to share. From episode #13, Drew Turner is a US Navy veteran who served in Iraq and Guantanamo Bay. He appeared in the kratom documentary A Leaf of Faith. Drew discusses … 64. Veterans Day Special: A Look Back on Four Veterans Who Told Us Their Kratom Stories Read More »
2021-11-1154 minKratom Science Podcast64. Veterans Day Special: A Look Back on Four Veterans Who Told Us Their Kratom StoriesNovember 11, 2021 is Veterans Day! We take a look back at four veterans of the United States military who had a kratom story to share.
From episode #13, Drew Turner is a US Navy veteran who served in Iraq and Guantanamo Bay. He appeared in the kratom documentary A Leaf of Faith. Drew discusses his injury inflicted by a prisoner at Guantanamo Bay, Meige syndrome, and cancer that may have been due to his exposure to burn pits. After trying various treatments, kratom became a tool in his wellness toolbox.
From episode #54, Afghanistan combat veteran Jaclyn O'Shea...
2021-11-1154 minKratom Science Podcast63. Chewing Kratom Leaves with Soren ShadeSoren Shade visits Brian in Pittsburgh bearing gifts: mature kratom leaves and a kratom plant the Top Tree Herbs greenhouse in West Virginia. This is the 2nd time the Hamilton's Pharmacopeia producer and kratom entrepreneur has been on the podcast - the first time being #47. Brian chews kratom for the first time, and we talk about the possibility of homegrown kratom in the USA, working with labs and scientists on measuring kratom alkaloids and their effects, the ongoing survey in cooperation with University of Florida scientist Dr. Oliver Grundmann, the Instapot method of making fresh leaf kratom tea, the...
2021-11-0457 minKratom Science63. Chewing Kratom Leaves with Soren ShadeSoren Shade visits Brian in Pittsburgh bearing gifts: mature kratom leaves and a kratom plant the Top Tree Herbs greenhouse in West Virginia. This is the 2nd time the Hamilton’s Pharmacopeia producer and kratom entrepreneur has been on the podcast – the first time being #47. Brian chews kratom for the first time, and we … 63. Chewing Kratom Leaves with Soren Shade Read More »
2021-11-0457 minKratom Science Podcast62. Dr. Fabian Pitter Steinmetz, Toxicologist Who Testified at the WHO Hearing on KratomDr. Fabian Pitter Steinmetz is a senior toxicologist from Germany and an outspoken advocate for harm reduction and science-based, rational drug policy. On October 11, 2021, representing the European Coalition for Just and Effective Drug Policies, Dr. Steinmetz testified against kratom prohibition for the World Health Organization's 44th Expert Committee on Drug Dependence . Dr. Steinmetz proposes three categories of a sensible drug policy, and we talk about why a history of safe use examined by social science is as important as pharmacological science, the importance of education about responsible use, the toxicology of kratom as compared to black tea, extracts vs...
2021-10-2159 minJournal Club with Dr. Jonathan CachatJournal Club #24: Kratom-Induced Psychosis? A Case ReportDr. Jonathan Cachat and host Brian Gallagher look at a case report of a supposed kratom-induced psychosis out of a student team from West Virginia University School of Medicine Department of Psychiatry, advised by MDs Alexander Muacevic and John R Adler.
A 43 year old man combat veteran with six tours of duty, traumatic brain injury, adrenal insufficiency, and post-traumatic stress disorder arrives at the ER with signs of psychosis. Prior to this, he hadn't slept in a week and ceased all medications including adderall, hormone pills, an antidepressant, and a weekly testosterone injection. He'd also been taking...
2021-08-2638 minJournal Club with Dr. Jonathan CachatJournal Club #23: Kratom alkaloid combo shown to help chemotherapy drug in killing cancer cells, more research neededPlease comment by August 9, 2021 to tell HHS/WHO to please keep kratom legal worldwide. Politely share your kratom story here, make sure you get a confirmation email and tracking number, and under "What are you commenting about?" Select "International Government - I0037" https://www.federalregister.gov/documents/2021/07/23/2021-15685/international-drug-scheduling-convention-on-psychotropic-substances-single-convention-on-narcotic?fbclid=IwAR1jTz7JSte491H5eTQBwjrivN4Y60s1t-kIPc1iy9UvnjfY2kkwHNFuBvM
Disclaimer: None of the content on this podcast or on KratomScience.com constitutes medical advice, nor is it intended to be the *wink wink* kind of medical advice. Go to a doctor if you're sick. Do...
2021-08-0538 minKratom ScienceJournal Club #23: Kratom alkaloid combo shown to help chemotherapy drug in killing cancer cells, more research neededPlease comment by August 9, 2021 to tell HHS/WHO to please keep kratom legal worldwide. Politely share your kratom story here, make sure you get a confirmation email and tracking number, and under “What are you commenting about?” Select “International Government – I0037” https://www.federalregister.gov/documents/2021/07/23/2021-15685/international-drug-scheduling-convention-on-psychotropic-substances-single-convention-on-narcotic?fbclid=IwAR1jTz7JSte491H5eTQBwjrivN4Y60s1t-kIPc1iy9UvnjfY2kkwHNFuBvM Disclaimer: None of the content on this podcast or on KratomScience.com … Journal Club #23: Kratom alkaloid combo shown to help chemotherapy drug in killing cancer cells, more research needed Read More »
2021-08-0538 minKratom ScienceEnter your kratom story into the public record to help keep kratom legal worldwidehttps://www.federalregister.gov/documents/2021/07/23/2021-15685/international-drug-scheduling-convention-on-psychotropic-substances-single-convention-on-narcotic?fbclid=IwAR1jTz7JSte491H5eTQBwjrivN4Y60s1t-kIPc1iy9UvnjfY2kkwHNFuBvM PUBLIC COMMENTS OPEN UNTIL AUGUST 9. This is a wonderful opportunity to enter your kratom story in the public record in the United States. Using the link above, your comment, as long as it’s polite and not overly angry, will be entered into the Federal Register! This comment could influence how the World Health … Enter your kratom story into the public record to help keep kratom legal worldwide Read More »
2021-07-2908 minJournal Club with Dr. Jonathan CachatJournal Club #22: Accelerated Solvent Extracts of KratomNeuroscientist Dr. Jon Cachat and host Brian Gallagher look at a study from University of Science in Malaysia that studies kratom extracts using various solvents: water, methanol, ethanol, and ethyl acetate. The technique they use, accelerated solvent extracting, uses less time and a lower amount of solvent for a safer and more environmentally friendly extraction technique. This technique has been established in botanical extractions, but is not commonly used for commercial kratom extracts. Some large kratom suppliers have been accused of outsourcing their extractions to China, and products come back containing toxic levels of residual solvents like chloroform and...
2021-07-0838 minJournal Club with Dr. Jonathan CachatJournal Club #21: Heroin to Buprenorphine to Kratom in AppalachiaStudy examined in this episode: Smith, K. E., Bunting, A. M., Walker, R., Hall, M. T., Grundmann, O., & Castillo, O. (2019). Non-Prescribed Buprenorphine Use Mediates the Relationship between Heroin Use and Kratom Use among a Sample of Polysubstance Users. Journal of psychoactive drugs, 51(4), 311–322. https://doi.org/10.1080/02791072.2019.1597224
Pubmed link https://pubmed.ncbi.nlm.nih.gov/30961450/
Link to all studies covered on Kratom Science Journal Club https://bit.ly/KratomSciPDFs
For #21 Brian and Dr. Jon Cachat look at a study of polysubstance users in Kentucky, most of whom were either currently incarcerated or had been incarcerated in the 7 ye...
2021-06-2447 minKratom Science Podcast53. Journalist Nick Wing on Covering KratomNick Wing is currently editor of the nonprofit journal The Appeal (theappeal.org). He spent nearly 10 years as a journalist for Huffington Post, where he did extensive in-depth reporting on kratom, starting in 2016. In the course of his work, Nick Wing discovered that one of FDA's "kratom-related deaths" was a man who died of a gunshot wound. He also examined countless medical examiner reports of supposedly kratom-caused deaths, questioned FDA and other officials for evidence of their claims that kratom is dangerous, and nearly got into a legal battle with a Pennsylvania coroner who refused to release toxicology reports...
2021-06-1749 minKratom Science53. Journalist Nick Wing on Covering KratomNick Wing is currently editor of the nonprofit journal The Appeal (theappeal.org). He spent nearly 10 years as a journalist for Huffington Post, where he did extensive in-depth reporting on kratom, starting in 2016. In the course of his work, Nick Wing discovered that one of FDA’s “kratom-related deaths” was a man who died of … 53. Journalist Nick Wing on Covering Kratom Read More »
2021-06-1749 minKratom ScienceJournal Club #20: Cholesterol Study on Kratom Users in ThailandA new study from Thailand (La-up, 2021) found traditional users of kratom had elevated levels of high-density lipoprotein (HDL or “good” cholesterol) and low levels of triglycerides. In the largest recent study of its kind, researchers recruited 581 participants, half kratom consumers, and half who did not consume kratom as a control group. Though the … Journal Club #20: Cholesterol Study on Kratom Users in Thailand Read More »
2021-06-1035 minJournal Club with Dr. Jonathan CachatJournal Club #20: Cholesterol Study on Kratom Users in ThailandA new study from Thailand (La-up, 2021) found traditional users of kratom had elevated levels of high-density lipoprotein (HDL or “good” cholesterol) and low levels of triglycerides. In the largest recent study of its kind, researchers recruited 581 participants, half kratom consumers, and half who did not consume kratom as a control group. Though the consumers of traditional kratom (fresh leaves brewed or chewed) had higher instances of drinking and smoking, they showed healthier cholesterol levels than the control group. Many fruits and vegetables rich in antioxidants also promote healthy cholesterol, and you'd expect that from a dark green leafy food like...
2021-06-1035 minJournal Club with Dr. Jonathan CachatJournal Club #19: The FDA’s Bad Science on KratomNeuroscientist Dr. Jonathan Cachat and host Brian Gallagher look at the blistering report by Jane Babin released in August 2018: "FDA Fails to Follow the Science on Kratom" (PDF available here https://t.co/G76TVsWdLY?amp=1 ). Babin demonstrates how FDA manipulated data to create a Schedule I justification based on what a former HHS Assistant Secretary of Health Brett Giroir called "embarrassingly poor evidence & data, and a failure to consider overall public health." FDA systematically omitted data, left out instances of polydrug consumption, failed to cite original case reports, and labelled suicides, homicides, and accidents as "kratom related deaths"...
2021-05-2749 minKratom Science Podcast51. Heroin, Kratom, and Comedy with David OakleyDavid Oakley is a stand up comedian from Atlanta. Previously addicted to heroin, Dave discovered kratom and it changed his life. He became active in kratom advocacy and attended the historic protest in Washington, DC in 2016 that helped keep kratom legal. Later, Dave began a career in stand-up comedy and moved to the small town of Durango in Southwestern Colorado. There he started a comedy production company called Comedy Uprising. During COVID, he moved back to Atlanta where you can find him on several open mics and comedy shows throughout the week. Comedy Uprising is organizing the Four Corners...
2021-05-2039 minKratom Science51. Heroin, Kratom, and Comedy with David OakleyDavid Oakley is a stand up comedian from Atlanta. Previously addicted to heroin, Dave discovered kratom and it changed his life. He became active in kratom advocacy and attended the historic protest in Washington, DC in 2016 that helped keep kratom legal. Later, Dave began a career in stand-up comedy and moved to the small … 51. Heroin, Kratom, and Comedy with David Oakley Read More »
2021-05-2039 minKratom Science Podcast50. The Kratom Genome with Julia Brose and Dr. Robin BuellBrian welcomes Julia Brose, graduate student at Michigan State University and lead author of the study "The Mitragyna speciosa (Kratom) Genome: A resource for data-mining potent pharmaceuticals that impact human health". She's joined by Dr. Robin Buell, MSU Distinguished Professor of Plant Biology, who co-authored the study.
We talk about the Rubiaceae family of plants, the process of studying the kratom genome, and plant genetics in general.
Study summarized: https://www.kratomscience.com/2021/03/10/kratom-genome-published/
Study referenced:
Brose, J., Lau, K. H., Dang, T., Hamilton, J. P., Martins, L., Hamberger, B., Hamberger, B., Jiang...
2021-05-0632 min
Kratom ScienceHamilton Morris, Soren Shade, and Dr. Oliver Grundmann Talk Kratom and a New SurveyTake the new anonymous kratom survey! tinyurl.com/kratomteasurvey Hamilton Morris, creator of Hamilton’s Pharmacopeia, and producer Soren Shade talk to University of Florida scientist and past Kratom Science Podcast guest Dr. Oliver Grundmann about his new anonymous research survey on kratom tea. All kratom consumers are invited to participate. Plus, how an overly positive kratom narrative … Hamilton Morris, Soren Shade, and Dr. Oliver Grundmann Talk Kratom and a New Survey Read More »
2021-04-191h 03Kratom Science PodcastHamilton Morris, Soren Shade, and Dr. Oliver Grundmann Talk Kratom and a New SurveyTake the new anonymous kratom survey! tinyurl.com/kratomteasurvey
Hamilton Morris, creator of Hamilton's Pharmacopeia, and producer Soren Shade talk to University of Florida scientist and past Kratom Science Podcast guest Dr. Oliver Grundmann about his new anonymous research survey on kratom tea. All kratom consumers are invited to participate.
Plus, how an overly positive kratom narrative can be just as misleading as a negative narrative, kratom dependence, quality standards, toxicity and safety, fresh vs. dried leaf, the variability of kratom product, labeling issues, and the stigma against opioids in general leading to under-prescription.
2021-04-191h 03Journal Club with Dr. Jonathan CachatJournal Club #16: Bioanalysis of 11 Alkaloids in Kratom Tea vs. Commercial ExtractAnother study from University of Florida is the “first report that has simultaneously evaluated the systemic exposure of 11 kratom alkaloids following the administration of traditional and commercial kratom products” (Kamble, 2021). Researchers looked at the pharmacokinectics (how drugs move through the body and are metabolized) of alkaloids in rat plasma following the oral administration of both kratom tea and a commercial liquid extract.
This study lays the groundwork for future research into the difference between “natural” kratom and extracts, and how the alkaloids act in concert, or as Dr. Cachat calls, the “entourage effect”, versus how they act separately.
2021-04-0147 minKratom ScienceJournal Club #16: Bioanalysis of 11 Alkaloids in Kratom Tea vs. Commercial ExtractAnother study from University of Florida is the “first report that has simultaneously evaluated the systemic exposure of 11 kratom alkaloids following the administration of traditional and commercial kratom products” (Kamble, 2021). Researchers looked at the pharmacokinectics (how drugs move through the body and are metabolized) of alkaloids in rat plasma following the oral administration … Journal Club #16: Bioanalysis of 11 Alkaloids in Kratom Tea vs. Commercial Extract Read More »
2021-04-0147 minJournal Club with Dr. Jonathan CachatJournal Club #15, Q&A Part 2: Kratom Legality, Kratom and Pharma, Dopamine Agonists, Libido, and Random EffectsNote: Nothing in this podcast or on KratomScience.com is intended to be medical advice, nor should it be taken as such. We’re not medical doctors. Please don’t listen to podcasts for advice on what you should or should not put in your body.
Dr. Cachat continues answering questions from February's r/kratom Ask Me Anything. This time we talk about whether kratom will follow the path of cannabis in terms of regulation, if kratom will be turned into a pharmaceutical drug, kratom and dopamine agonists, kratom and libido, and random weird effects that probably aren...
2021-03-1833 minJournal Club with Dr. Jonathan CachatJournal Club #14, Q&A Part 1: Kratom and Liver Enzymes, Alcohol, Pain Management, and SerotoninNote: Nothing in this podcast or on KratomScience.com is intended to be medical advice, nor should it be taken as such. We're not medical doctors. Please don't listen to podcasts for advice on what you should or should not put in your body.
For episode #14, Dr. Jonathan Cachat answers half of the remaining question from our February 23rd r/kratom Reddit AMA. There were so many questions, we divided this into two episodes.
In Part 1 questions are answered about kratom and liver enzymes, kratom in combination with alcohol and other substances, kratom vs. classical...
2021-03-0434 minKratom Science Podcast45. Dr. Abisheak Sharma, Pharmacokineticist and Kratom ResearcherDr. Abisheak Sharma studied pharmacy and pharmacokinetics in India before coming to the United States to research under kratom expert Dr. Bonnie Avery. He now researches kratom with Dr. Christopher McCurdy at University of Florida as part of the Translational Drug Development Core. Dr. Sharma addresses the concern with kratom and other drug interactions, improved chromatography methods of identifying kratom alkaloids, research on kratom plants being grown by University of Florida, and where we are with kratom and human clinical trials.
A full transcription of this podcast is forthcoming and will be linked here
Music...
2021-02-2545 minJournal Club with Dr. Jonathan CachatJournal Club #13: How Kratom Alkaloids Act on Brain ReceptorsWe all know the mitragynine and 7-hydroxymitraginine act on the mu-opioid receptor. But for episode #13 of Journal Club we talk about a study that looks closely at the binding affinity of various kratom alkaloids on the plethora of opioid and adrenergic receptors in the brain. How exactly does this work? How do different alkaloids lead to the multiple functional effects of kratom? Are we fish out of water when it comes to molecular chemistry? Guesses and possibly even answers, plus listener mail, in episode #13 of Kratom Science Journal Club.
Study cited in this episode:
Obeng...
2021-02-1839 minJournal Club with Dr. Jonathan CachatJournal Club #12: Kratom Cultivation StudiedThis time Dr. Jonathan Cachat and I look at a study where a team from University of Florida cultivated 68 kratom trees in a greenhouse, gave them varying levels of fertilizer, and measured for biomass, chlorophyll, and alkaloid content. Dr. Jon talks about similar studies he did with cannabis, and we go into what that would mean for a domestic kratom agriculture industry, home growers, and further science on the plant biology of kratom.
Article discussed in this episode: Zhang M, Sharma A, León F, et al. Effects of Nutrient Fertility on Growth and Alkaloidal Content in M...
2021-01-2833 minKratom Science Podcast43. Kratom Addiction w. Dr Cornel Stanciu and Dr. Thomas PendersMy guests are two addiction psychiatrists, Dr. Cornel Stanciu and Dr. Thomas Penders. I responded to their webinar in episode 38. I thought they overstated the dangers of kratom and wondered why you’d prescribe buprenorphine for kratom withdrawals. We talk about that, and the topic of kratom addiction and addiction in general.
Studies referenced to in this podcast:
"Best Practices in Managing Patients with Kratom Addiction" webinar by Dr Stanciu and Dr Penders https://pcssnow.org/event/best-practices-in-managing-patients-with-kratom-addiction/
Kratom Science Podcast #38: "Psychiatrists Overstate the Dangers of Kratom" https://www.kratomscience.com/podcast/38-psychiatrists-overstate-the-dangers-of-kratom/...
2021-01-2152 minJournal Club with Dr. Jonathan CachatJournal Club #10: Kratom and AlcoholHappy Thanksgiving! The holidays after a rough year are always a great time to drink like a fish. In this episode we explore kratom and alcohol. Emerging testimony and research indicates kratom may be an effective harm reduction tool to cut down on alcohol consumption, withdrawal, and cravings. We read testimony from KratomScience.com commenters, then get into a study showing four isolated kratom alkaloids all decreased alcohol consumption in mice.
Article discussed in this episode: Gutridge AM, Robins MT, Cassell RJ, Uprety R, Mores KL, Ko MJ, Pasternak GW, Majumdar S, van Rijn RM. G protein-biased...
2020-11-2638 minJournal Club with Dr. Jonathan CachatJournal Club #8: Kratom Tea for Opioid Dependence in MiceThis week we look at a study by a team from University of Florida called “Lyophilized Kratom Tea as a Therapeutic Option for Opioid Dependence”. The science is catching up with what thousands of kratom consumers are saying -- that kratom can be a safe and effective harm reduction tool for opioid withdrawal and dependence. In 2018 and 2019, University of Florida College of Pharmacy received close to $7 million in grants from the National Institutes on Drug Abuse to study kratom.
Study discussed in this episode: Wilson LL, Harris HM, Eans SO, Brice-Tutt AC, Cirino TJ, Stacy HM, Simons CA...
2020-10-2943 minJournal Club with Dr. Jonathan CachatJournal Club #7: Kratom Use and Mental Health w/ Dr. Marc Swogger and Dr. Jonathan CachatHost Brian Gallagher and Dr. Jonathan Cachat welcome Dr. Marc Swogger, social scientist and clinical psychologist at the University of Rochester Medical Center to discuss his 2018 article published in Drug and Alcohol Dependence "Kratom Use and Mental Health: A Systematic Review". Along with co-author Zach Walsh, Dr. Swogger looked at all the literature published up to 2017 about mental health issues surrounding kratom consumption. We talk about why mostly men use kratom, cultural differences between Eastern and Western kratom consumption, the consistency of outcomes among careful kratom science vs. sloppy studies with foregone negative conclusions. Plus, Dr. Marc answers another...
2020-10-1544 minKratom Science Podcast38. Psychiatrists Overstate the Dangers of KratomIn a recent webinar, psychiatrists describe kratom as dangerous with lethal overdose and toxicity potential. Using the studies they cite, Brian Gallagher explains why the dose of mitragyinine to establish LD50 in mice is far beyond the levels consumed in leaf and even extracted kratom, and why one investigation into coroners’ reports disproved claims of so-called “kratom alone” deaths. Plus, will psychiatrists administer buprenorphine for kratom withdrawal?
https://www.kratomscience.com/2020/10/06/toxic-levels-of-kratom-and-lethal-dose-of-mitragynine/ "Toxic Levels of Kratom and LD50 of Mitragynine"
https://doi.org/10.1021/acs.chemrestox.8b00218 "Lateral Flow Assessment and Unanticipated Toxicity of Kratom" Chem. Res. T...
2020-10-0822 minJournal Club with Dr. Jonathan CachatJournal Club w/ Dr. Jonathan Cachat #4: Human Evolution and Psychoactive Plants, Scratching the Surface of Kratom History, and Kratom AlkaloidsThis episode, Dr. Jon and I use the journal article "Following the Roots of Kratom" published in 2015 by BioMed Research International as a jumping off point to talk about kratom history, human evolution and psychoactive plants, Terence McKenna's "Stoned Ape" theory, and drug in religious cults . Plus, we answer listener mail about kratom alkaloids and use as an antidepressant.
References featured in this discussion:
Cinosi, E., Martinotti, G., Simonato, P., Singh, D., Demetrovics, Z., Roman-Urrestarazu, A., Bersani, F. S., Vicknasingam, B., Piazzon, G., Li, J. H., Yu, W. J., Kapitány-Fövény, M., Farkas, J...
2020-08-2048 minJournal Club with Dr. Jonathan CachatJournal Club with Dr. Jonathan Cachat #2: “The Potential for Kratom as an Antidepressant and Antipsychotic”This is the Kratom Science Journal Club with Dr. Jonathan Cachat, neuroscientist and expert in psychopharmacology. In each episode we discuss an article in a peer reviewed journal.
For episode 2 we discuss the article, “The Potential for Kratom as an Antidepressant and Antipsychotic” published in Yale Journal of Biology and Medicine, edition 93, June 2020 and co-authored by Kratom Science Podcast guest Marc Swogger.
How do dopamine, serotonin, and cortisol work to affect psychosis and depression? What effect does mitragynine have on our brains? How is mitragynine metabolized? How does kratom work differently from opiates and psychedelics? And...
2020-07-2348 minKratom Science Podcast26. Scars: How 20+ Surgeries Led to the Revelation That is KratomMy guest is Scars Hernandez from Dayton Ohio. Scars earned his name from over 20 surgeries in his lifetime. In 2018, after years of being addicted to pills, he found kratom..He’s now active in the movement to keep kratom legal in Ohio. This is Scars, and this is his kratom story...
Music: Risey "Memories of Thailand"
The Kratom Science Podcast is written and produced by Brian Gallagher for KratomScience.com
Disclaimer: There is no content on the Kratom Science Podcast nor on KratomScience.com that in any way constitutes medical claims or medical adv...
2020-06-0225 minKratom Science Podcast24. Kratom Gave Me My Life Back with Kami Ann DavisMy guest is Kami Ann Davis. Kami was in a rafting accident in her 20s that led to a life of chronic pain.. She went on to become a nurse. The physical strain of nursing combined with the opioid medications for her chronic pain led her to search for an alternative. Kami discovered kratom has become an advocate for the plant that she says provides focus, energy, as well as pain relief. This is Kami Ann Davis, and this is her kratom story.
Kami's article "Kami Davis: I Got My Life Back After 20 Years by Taking Kratom"...
2020-05-1927 minKratom Science Podcast15. Marketing in a Kratom-Restrictive World with Wade Harman My guest is Wade Harman from Richlands, Virginia. Wade is a former coal miner, now a freelance writer, kratom consumer of 18 years, and host of the podcast The Botanical Resistance. We talk about FDA links to big pharma, marketing in a kratom-restrictive social media world, and how Wade survived an opiate addiction with the help of kratom.
Written and produced by Brian Gallagher for KratomScience.com
Music: Risey, "Memories of Thailand"
Wade Harman's podcast, The Botanical Resistance https://botanicals.podbean.com/
Twitter @wadeharman
Disclaimer: There is no content on t...
2020-03-1037 min