Shows
MDedge CardiocastTop stories from the American Heart Association scientific sessions ISCHEMIA trial hailed as practice changing The largest-ever RCT of initial invasive versus conservative management of stable ischemic heart disease makes waves. DAPA-HF: Dapagliflozin’s HFrEF efficacy confirmed in nondiabetics Further analyses from the DAPA-HF trial showed dapagliflozin cut death and heart failure events in HFrEF patients with no diabetes. Colchicine cut post-MI CVD events Colchicine fulfilled the promise first seem in CANTOS that anti-inflammatory treatment can reduce cardiovascular disease events. Getting high heightens stroke, arrhythmia risks Cannabis use or abuse among the young was associated with adverse cardiovascular co...
2019-12-2707 min
MDedge CardiocastCard Talk: TAVR and glass ceilingsThis week’s Cardiocast is devoted entirely to Card Talk with cardiologist brothers Jim and Jerry Dwyer. They welcome two structural interventionalists at the Structural Heart and Valve Center at Emory Healthcare, Kendra J. Grubb, MD, and Isida Byku, MD. Both followed a unique track, training in both cardiac surgery and interventional cardiology and practicing in the fast-moving field of structural heart disease. * * * Help us make this podcast better! Please take our short listener survey: https://www.surveymonkey.com/r/podcastsurveyOct2019 * * * From the “picture that went around the world” of an all-female t...
2019-11-2943 min
MDedge CardiocastISCHEMIA trial, DAPA-HF, and valsartan recall: AHA SpecialIn this special meeting edition of the Cardiocast, MDedge Cardiology editor Catherine Hackett is joined by MDedge reporters Mitchel L. Zoler, Bruce Jancin, and Richard Mark Kirkner. The MDedge cardiology team reviews three big stories from the 2019 annual scientific sessions of the American Heart Association in Philadelphia. * * * Help us make this podcast better! Please take this short listener survey: https://www.surveymonkey.com/r/podcastsurveyOct2019 * * * ISCHEMIA trial hailed as practice changing The results of the ISCHEMIA trial were emphatically declared practice changing by interventional cardiologists and noninterventionalists ali...
2019-11-2632 min
MDedge CardiocastCV cost of smoking lasts a quarter centuryThis week in cardiology: PCSK9 inhibition cuts events in very-high-risk groups ODYSSEY OUTCOMES analyses peg prior CABG and polyvascular disease as targets for alirocumab. Cardiovascular cost of smoking may last up to 25 years Past smokers face an elevated cardiovascular risk for up to 25 years after they quit. Impact of climate change on mortality underlined by global study This may be the largest study ever to assess the effects of inhalable particulate matter around the world. HCV coinfection adds to the cardiovascular risk in HIV-infected patients Hepatitis C virus and other injections were independently linked...
2019-08-3007 min
Postcall PodcastAdvice for new med students and Dr. Julie CroleyMedTwitter stars and clinicians give their best advice for medical students as medical school resumes and @dr.skinandsmiles (Julie Amthor Croley, MD) joins Nick Andrews to talk about doctors on social media, podcasting, long-distance doctor marriages, and more. Links: Twitter advice for medical students thread Dr. Julie Amthor Croley Instagram Profile Resident Take Overs On social media in dermatology Being on-call as a derm resident Tips on patient communication Prescribing combined OCs Dr. Croley on MDedge MDedge Podcasts Blood & Cancer Cardiocast Daily Medical News Derm Weekly Psychcast You can email the show at podcasts@mdedge.co...
2019-08-2331 min
MDedge CardiocastTwo FDA approvals, smoking impacts CV health for 25 years TAVR valves now FDA approved for low-risk patients The FDA's decision will expand TAVR access to younger, healthier patients. FDA approves baroreflex activation for advanced HF A phase 4 trial will investigate impact on hospitalizations and mortality. Top line results: Dapagliflozin meets primary endpiont in DAPA-HF AstraZeneca announces preliminary results in first heart failure trial in an SGLT2 inhibitor. Cardiovascular cost of smoking may last up to 25 years Past smokers face an elevated cardiovascular risk for up to 25 years. You can contact the MDedge Cardiocast by emailing us at podcasts@mdedge.com or following us on...
2019-08-2308 min
MDedge CardiocastNSAIDS mediate CV risk and hypertension linked to dementiaThe top news in cardiology: Midlife hypertension linked to dementia risk Elevated blood pressure in midlife is associated with risk of subsequent dementia, but whether the risk is treatable is unclear. Ambulatory BP slightly better than in-office measures for predicting cardiovascular outcomes It’s probably best to save these techniques for specific patients. NSAIDs a significant mediator of cardiovascular risk in osteoarthritis NSAID use could be responsible for a significant proportion of the increased risk of cardiovascular disease associated with osteoarthritis. Burnout gets personal for 68% of physicians Burden hits primary care more than spec...
2019-08-1608 min
MDedge CardiocastAI for AFib and acupuncture for anginaThe top stories in cardiology: Artificial intelligence technology meets AFib detection An AI-enabled ECG model suggests clinical implications for early identification of atrial fibrillation. Older patients who stop statins may be increasing their cardiovascular risk Discontinuation of statins was associated with an increased risk of hospital admission for a cardiovascular event. Psoriasis patients on biologics show improved heart health Novel imaging biomarker identifies reduced coronary inflammation in psoriasis patients on biologics. Acupuncture cuts attacks in chronic angina Chronic stable angina patients showed significant improvement with acupuncture over patients given shame or no acupuncture. ...
2019-08-0909 min
MDedge CardiocastSeven simple rules of heart failure risk - you only need twoThe top news in cardiology: Meeting just 2 of 7 ‘simple’ goals lowers HF risk American Heart Association recommendations seem to lower risk even if only a couple of the 'Simple 7' are mastered. Increased cardiovascular risk seen early on with testosterone replacement therapy Testosterone replacement therapy for low testosterone is linked to an early increase in the risk of cardiovascular and cerebrovascular events. No increase in UTI risk with SGLT-2 inhibitors SGLT-2 inhibitors are not associated with an increased risk of severe urinary tract infections. As patients, physicians fare nearly the...
2019-08-0207 min
MDedge CardiocastAir pollution correlated with cardio mortality; statins crush early seizure risk Statins crush early seizure risk poststroke Statin initiation upon hospitalization for acute ischemic stroke was linked to a major antiseizure benefit in a Japanese study. Atherosclerotic disease risk persists after smoking cessation Clinicians should reinforce smoking cessation with awareness that risk for several atherosclerotic diseases remains significant for decades. Air pollution levels correlated with cardiorespiratory mortality; reduced life expectancy Fine particulate matter pollution is associated with increased cardiorespiratory mortality, particularly in lower-income areas. Exercise counters astronauts' dizziness after space flight Two hours of daily activity during space flight eliminated hypotension after landing. You can contact t...
2019-07-2608 min
MDedge CardiocastHalf of sudden cardiac deaths linked to silent MI; Uncontrolled hypertension and dementiaThis week in cardiology: Systolic, diastolic BP each tied to adverse CV outcomes Diastolic hypertension can't be ignored, though systolic ultimately has a larger impact. Almost half of sudden cardiac deaths linked to prior silent MI Prior silent MIs were detected in nearly half of sudden cardiac deaths in people with no coronary artery disease. How does uncontrolled hypertension play into dementia? Findings from a French cohort suggest that a vascular pathway, independent of amyloid, bears on cognitive decline. Vaping device marketers take aim at youth through social media More than a third of J...
2019-07-1909 min
MDedge CardiocastOmega-3s cut heart failure; Fat-but-fit theory takes a hitThe top stories in cardiology: New findings cast more doubt on fat-but-fit theory Patients who are obese and metabolically healthy face higher cardiac risk Higher omega-3 fatty acid levels cut heart failure risk A large multi-ethnic cohort study shows significantly higher levels of EPA in adults without heart failure. Microvascular disease: An independent and exacerbating risk factor for amputation The presence of microvascular disease plus peripheral artery disease resulted in a more than 20-fold increased risk of amputation that MVD or PAD. Court halts rule requiring drug list pricing in advertising Judge n...
2019-07-1208 min
MDedge CardiocastLipoprotein(a) levels and genes boost ischemic stroke riskThis week's top stories in cardiology: Lipoprotein(a) levels, genes boost ischemic stroke risk Could some elderly skip statins based on negative risk markers? Cardiac events jump after COPD exacerbation CAROLINA findings reaffirm linagliptin’s safety, free glimepiride of CV-risk stigma You can contact the MDedge Cardiocast by emailing us at podcasts@mdedge.com or following us on Twitter at @MDedgeTweets.
2019-07-0508 min
MDedge CardiocastCHD sped cognitive decline and other cardiology newsThis week's top stories in cardiology: Cognitive decline sped up after CHD Genetic analysis links PCSK9 inhibition and CV mortality Which antidiabetic for elderly patients? It depends on their CV risk Pivotal trial shows HFrEF benefits from baroreceptor stimulation You can contact the Cardiocast by emailing us at podcasts@mdedge.com or you can interact with us on Twitter @MDedgeCardio
2019-06-2108 min
MDedge CardiocastAlirocumab reduces MIsThis week in clinical cardiology: Alirocumab reduces both type 1 and 2 MIs. Despite failed primary endpoint, MI alert device has predictive value. Look for alcohol septal ablation in the next HOCM guideline. FDA: Forty ARBs free of nitrosamines. You can contact the Cardiocast with ideas, suggestions, stories, or questions for Dr. Dwyer by emailing us at podcasts@mdedge.com and you can follow MDedge Cardiology on Twitter at @MDedgeCardio.
2019-04-1208 min
MDedge CardiocastNew LDL-lowering drug is under FDA reviewThis week in MDedge Cardiocast: A novel drug lowers LDL in on top of maximums statins, invasive cardiology is a top money maker for hospitals, a meta-analysis parses the heart and kidney benefits of new diabetes drugs, and the AHA warns that heart-harming toxins may hurt hookah smokers.
2019-03-1506 min
MDedge CardiocastForget what you learned about infective endocarditisThis week in MDedge Cardiocast: Infective endocarditis isn’t what it used to be, there’s a new, lower goal for Americans’ dietary intake of sodium, a drug to treat myeloma also raises heart failure risk, and Big Pharma says it can’t drop drug list prices alone.
2019-03-0806 minMDedge CardiocastWhat comes first with SGLT2 inhibitors – diabetes or heart failure?This week in MDedge Cardiocast: Most tPA-eligible stroke patients now get treated within an hour, LAA closure can be treated safely in patients with prior hemorrhagic stroke, SGLT2 inhibitors are quickly morphing from diabetes to heart failure drugs, and the MESA cardiovascular disease risk calculator can be an improvement on the ACC/AHA version.
2019-02-1508 min
MDedge CardiocastSleep: Too much, too little both tied to atherosclerosisThis week in MDedge Cardiocast: too little sleep, too much sleep, and fragmented sleep are all linked to atherosclerosis; dabigatran matches aspirin for second stroke prevention; HDL particle subfractions may be prognostic in heart failure; and a novel drug safely reduced LDL cholesterol in statin-intolerant patients.
2019-01-1807 min
MDedge CardiocastReducing heart failure readmissions raises mortalityThis week in Cardiocast, the Hospital Readmissions Reduction Program may be doing more harm than good, ticagrelor holds no edge over aspirin in CABG patients, weight-loss apps lack evidence, and the Surgeon General sends out an alarm.
2019-01-0406 min
MDedge CardiocastAHA 2018: Part IIn this episode of the Cardiocast, the MDedge Cardiology team of reporters breaks down the 2018 annual scientific session of the American Heart Association.
2018-11-1652 min
MDedge CardiocastBradycardia guidelines, hypertension's risk in young adults, and moreThis week on Cardiocast, guidelines for bradycardia set a new bar for shared decision-making in pacemaker placement, young adults with hypertension may be at higher CVD risk, how sleep quality affects cardiovascular risk, and a strong showing for exercise in patients with both heart failure and sleep apnea. Tune in next Friday for the most exciting news from the scientific sessions of the American Heart Association, as told by the reporters who cover it.
2018-11-0908 min
MDedge CardiocastTop news from TCT, anticoagulation guidelines, and moreThis week, a breakthrough for heart failure patients with mitral regurgitation emerges, prosthesis-patient mismatch raises the risk of death following TAVR, a new study challenges anticoagulation guidelines, and a possible blessing in disguise for rivaroxaban comes from the massive COMPASS trial. Subscribe to Cardiocast wherever you get your podcasts. Amazon Alexa Apple Podcasts
2018-09-2807 min
Daily Medical NewsA hidden bonus for rivaroxaban?Bleeding from rivaroxaban may help diagnose some GI and GU cancers (http://bit.ly/2O6YfCf [Cardiocast: http://bit.ly/2xJNOdv]). Also today, a review by the FDA supports the safety of nuplazid (http://bit.ly/2pxT5Bw), arthritis is prevalent in older adults with any degree of depression (http://bit.ly/2xxTXug), and growth in overdose deaths is exponential (http://bit.ly/2xIHG5xf).
2018-09-2406 min
MDedge CardiocastDOACs found safer than warfarin in the real worldThe safety of direct oral anticoagulants is affirmed in a real-world study; a wearable ECG boosts atrial fibrillation detection by a factor of 8; new pediatric guidelines catch more hypertension cases in children; and nontraditional cardiovascular risk factors are not ready for prime time, says a federal task force. Listen to MDedge Cardiocast for all the details on the week’s top news, and subscribe on iTunes.
2018-07-1307 min
MDedge CardiocastAmplatzer slashes stroke risk in high-risk AF patientsLeft atrial appendage closure slashes stroke risk in high-risk atrial fibrillation patients with Amplatzer Amulet; how diabetes patients fared with alirocumab in ODYSSEY Outcomes; the new word in stents is "abluminal"; and cheerful news about midlife fitness. Listen to Cardiocast for the week's top news.
2018-06-2908 min
MDedge CardiocastBotox, PVCs, and statinsTranscatheter aortic valves delivered better hemodynamic valve performance and less structural valve deterioration than surgical valves over 6 years. Transcatheter aortic valves outlast surgical valves in the NOTION study presented at EuroPCR. From Heart Rhythm 2018, a registry study suggests myocarditis is the culprit in many cases of frequent premature ventricular contractions, and one set of Botox shots into intracardiac fat pads cut atrial fibrillation for up to 3 years. Also this week, many patients with NAFLD and abnormal alanine aminotransferase should be taking a statin but aren’t, and why statins reduce the risk of lethal prostate cancer. Li...
2018-06-0708 min
MDedge CardiocastBig surprises from EuroPCRWelcome to the MDedge Cardiocast, the new weekly podcast from Cardiology News. We start with news from Paris, where EuroPCR saw noninvasive diagnostic methods defy accepted practice in patients with triple-vessel and stable coronary artery disease, as well as a resurrection of renal denervation for hypertension.
2018-06-0109 min