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Blood & CancerBlood & CancerBiosimilars with Dr. Gary LymanExisting biosimilars are safe, effective alternatives to their reference biologics, and are increasingly being incorporated into oncology treatment guidelines. Technological advances that have emerged in the years since biologic agents entered the market allow for the careful assessment of “critical clinical attributes” of biosimilar agents. This helps ensure the safety and efficacy of biosimilars, as well as their structural, functional, and behavioral similarities to the original reference biologics, according to Gary Lyman MD, MPH, professor and senior lead, health care quality and policy at the Hutchinson Institute for Cancer Outcomes Research at Fred Hutchinson Cancer Research Center, Seat...2021-05-2732 minBlood & CancerBlood & CancerGene therapies in hemophilia with Dr. Glenn PierceA “very basic” type of gene therapy could potentially cure hemophilia, but a major hurdle has been the lack of an effective mode of delivery. Recent strides in using adeno-associated virus (AAV) vectors are changing that, and Glenn Pierce, MD, World Federation of Hemophilia Vice President, Medical, predicts approvals in the next 12-18 months. Dr. Pierce shared his personal experience with hemophilia and discussed his and others’ ongoing research on the use of AAV-mediated gene therapy with host David Henry, MD, in this episode. Hemophilia and AAV gene therapy key points: Hemophilia is caused by a m...2021-05-1324 minBlood & CancerBlood & CancerThrombosis and thrombocytopenia caused by COVID-19 vaccines: How to identify and treat VITT, VIPIT, or TTSAt least 17 cases of thrombosis and thrombocytopenia have been reported in patients who received the Johnson & Johnson COVID-19 vaccine in the United States. Such events have been reported in patients who received the AstraZeneca vaccine as well. In this episode, Adam C. Cuker, MD, of the University of Pennsylvania, Philadelphia, tells host David H. Henry, MD, how to identify and manage patients with these vaccine-induced events. What’s in a name? The phenomenon of vaccine-induced thrombosis and thrombocytopenia has been given different names, including: Vaccine-induced immune thrombotic thrombocytopenia (VITT) Vaccine-induced prothrombotic immune thrombocytopenia (VIPIT) Thrombosis and thrombocytopenia syndrome (TT...2021-05-0623 minBlood & CancerBlood & CancerToward more personalized treatment in prostate cancer: The CCR score predicts metastasis and guides treatment decisions after radiationThe combined clinical cell-cycle risk (CCR) score uses clinical and genetic factors to assess the risk of metastasis after radiation therapy in patients with prostate cancer. The CCR score has proven accurate in studies and can guide post-radiation treatment decisions in practice, according to Jonathan D. Tward, MD, PhD, of the University of Utah, Salt Lake City. Dr. Tward discusses the CCR score with host David Henry, MD, in this episode. About the score The CCR score combines the cell-cycle progression (CCP) score (available commercially as the Prolaris test) and the Cancer...2021-04-2928 minDermatology WeeklyDermatology WeeklyEquitable access to dermatologic careEthnic minorities and patients living in socioeconomically disadvantaged areas are disproportionately impacted by a growing national shortage of dermatologists. In this resident takeover, Sophie A. Greenberg, MD (Twitter: @sophiegreenberg; Instagram: @sophiegreenbergmd), talks to Soraya Azzawi, MD, about how dermatology residency can serve as an opportunity to address barriers to equitable care in these populations and enact change within the specialty: “There is a stark regional misdistribution of the dermatologic workforce, with specialists tending to concentrate in the urban areas, and more rural areas are largely underserved. And as we progress through residency and start thinking about the overall trajectory of...2021-04-2915 minBlood & CancerBlood & CancerChanging perspectives: Dr. Michael Weiner recounts his experiences as an oncologist who became a cancer patient and then a caregiverPediatric oncologists are used to dealing with emotional, heart-wrenching situations, but oncology took on a new dimension for Michael Weiner, MD, when both he and his daughter were diagnosed with cancer. Dr. Weiner, a pediatric oncologist at Columbia University, New York, describes his roles as oncologist, patient, and caregiver to host David H. Henry, MD, in this episode.  Oncologist as patient: Lessons learned Dr. Weiner’s journey as a cancer patient began when he felt a lymph node on his neck that he knew wasn’t “normal.” A colleague examined Dr. Weiner and suggested the “watc...2021-04-2225 minDermatology WeeklyDermatology WeeklyHighlights from the 2021 American Contact Dermatitis Society MeetingThis week, Amber Atwater, MD, the immediate past president of the American Contact Dermatitis Society, reviews some highlights from the meeting, which was held in March. Dr. Atwater, associate professor of dermatology at Duke University, Durham, N.C., discusses the 2021 “Contact Allergen of the Year,” a chemical that has been linked to reactions associated with shin pads and is an emerging allergen that was the topic of a recent report in Dermatitis. Joining Dr. Atwater, Raina Bembry, MD, a dermatitis fellow at Duke University, provides the results of a study of shoe allergens she presented at t...2021-04-2220 minDermatology WeeklyDermatology WeeklyEducational photographs need to better represent the entire patient populationRecent studies have highlighted poor representation of darker skin types in dermatology textbooks and online resources. Vincent A. DeLeo, MD, talks to Jules B. Lipoff, MD (@juleslipoff), about the general paucity of images of skin of color in learning resources as well as an overrepresentation of darker skin types in material about sexually transmitted infections. “We should be teaching our students and our residents. It shouldn’t be just a skin of color lecture. Skin of color should be through every lecture. We should be showing how everything presents in every skin type,” Dr. Lipoff notes. They also discuss the fl...2021-04-1516 minDermatology WeeklyDermatology WeeklyCoding and reimbursement changes for skin biopsiesIn 2019, the two CPT codes for skin biopsies were replaced with six new codes that specify biopsy technique and associated procedural complexity. Vincent A. DeLeo, MD, talks to medical student Sheena Desai and Rebecca I. Hartman, MD, MPH, about this CPT change and its effect on the frequency of shave versus punch biopsies in both private and academic practices. “The average dermatologist needs to be cognizant of the fact that changing reimbursements may hypothetically influence [the] provider’s decision on what biopsy type to perform,” Ms. Desai notes. They also explain how this data can be extrapolated at a nation...2021-04-0810 minBlood & CancerBlood & CancerImproving cancer screening in the COVID era: Drive By Flu-FIT allows for socially distanced colorectal cancer screeningA program called Drive By Flu-FIT has allowed for socially distanced colorectal cancer (CRC) screening during the COVID-19 pandemic. Armenta Washington, senior research coordinator at the University of Pennsylvania, describes the program to guest host Alan Lyss, MD, subprincipal investigator emeritus for Heartland Cancer Research NCORP, in this episode. What is Drive By Flu-FIT? Drive By Flu-FIT is a socially distanced version of the Flu-Fecal Immunochemical Test (Flu-FIT) program. Flu-FIT was designed to increase access to CRC screening by offering take-home FIT tests to patients at the time of their annual flu shots. The...2021-04-0125 minDermatology WeeklyDermatology WeeklyCutaneous clinical signs of COVID-19COVID-19 affects multiple organ systems, and skin manifestations are prevalent. Dr. Vincent DeLeo talks to medical student Lauren Schwartzberg and Ann Lin, DO, about both common and rare cutaneous presentations of COVID-19. “I think it’s important to look at the unexplained rashes a little differently now than ever before the COVID era ... a thorough history of COVID-19 exposures and perhaps even COVID-19 testing should be considered,” Ms. Schwartzberg notes. They also discuss differences in presentation seen in adult and pediatric patients. Article: https://www.mdedge.com/dermatology/article/235467/infectious-diseases/cutaneous-manifestations-covid-19 Downloadable PDF: https://cdn.mdedge...2021-04-0109 minDermatology WeeklyDermatology WeeklyDon’t overlook the genitals during a total-body skin examinationRecent surveys show that dermatologic examinations tend to neglect the genital area. In this resident takeover, Sophie A. Greenberg, MD (@sophiegreenberg), talks to Margaret Maria Cocks, MD, PhD (@Margaret_Cocks), about the lack of focus on the genital area in the total-body skin examination (TBSE), especially in female patients, and the paucity of training on genital examinations in residency. “While [melanoma] is rare, a lot of the time when genital melanomas are identified, they’re often found later and more aggressive stages ... partially that might be because this area is not routinely examined by any care provider,” Dr. Cocks notes...2021-03-2522 minDermatology WeeklyDermatology WeeklyTeledermatology beyond the COVID-19 pandemicBefore the COVID-19 pandemic, telemedicine largely was underutilized in dermatology. Vincent A. DeLeo, MD, talks to George Han, MD, PhD, about the progression of the reimbursement process and the roadblocks encountered with the expansion of telemedicine. “To me, telemedicine really represents the opportunity to make a dent in access to care ... expanding our access to care, especially in underserved areas in places where a lot of people have barriers, people of lower socioeconomic status, skin of color ... there’s a lot of populations out there where we’re just not able to get the level of coverage and access to der...2021-03-0419 minDermatology WeeklyDermatology WeeklyApplying for dermatology residency as a student of colorTo truly increase diversity in dermatology, students of color need to be encouraged that dermatology is achievable. In this resident takeover, Sophie A. Greenberg, MD (@sophiegreenberg), talks to Nicole A. Negbenebor, MD (Instagram: @naijalatte), about her personal experience navigating dermatology residency as an applicant of color. “Dermatology is such a wonderful field and I feel that it has had the ability to impact so many different people, different socioeconomic statuses, different backgrounds, but unfortunately the workforce does not reflect the population sometimes that they’re serving,” Dr. Negbenebor notes. They also discuss the importance of mentorship and networking opportunities, and Dr...2021-02-2512 minDermatology WeeklyDermatology WeeklyTop apps for dermatology educationMobile applications are useful to educate medical students and trainees; however, there is no objective method to assess their quality. Vincent A. DeLeo, MD, talks to Babar Rao, MD, about determining the usefulness and credibility of dermatology educational apps including factors such as affordability, accuracy, and ease of use. “I think we will be dependent on digital learning, so the only way to really move forward is to get involved. ... I think we have to get involved and make sure that what is available on these digital educational portals is also as relevant or as accurate as our printed ma...2021-02-1115 minDermatology WeeklyDermatology WeeklyRural dermatology training and expanding access to careTranscript of this episode is avaiable at: https://www.medscape.com/viewarticle/946600?src= Access to dermatologic care in rural areas is a growing problem. Dr. Vincent DeLeo talks to Robert T. Brodell, MD; Cindy Firkins Smith, MD; and medical student Alexandra Streifel about the influence of rural clinical experiences during residency, which may increase the likelihood of trainees establishing a practice in these isolated areas. “Rural areas are tremendously underserved. [Patients] are waiting months to get appointments. And so if we can increase the number of rural dermatologists, it’s primarily good for patients,” Dr. Smith notes. They a...2021-02-0418 minDermatology WeeklyDermatology WeeklyCounseling patients on diet and common skin conditions; plus, acne guidelinesIn the news: Dermatologist survey spotlights psoriasis care deficiencies in reproductive-age women Expert panel addresses gaps in acne guidelines                                         * * * There is strong evidence for a relationship between diet and various skin conditions. In this resident takeover, Daniel R. Mazori, MD, talks to Sophie A. Greenberg, MD (@sophiegreenberg), about the role of diet in acne, psoriasis, and atopic dermatitis. Because patients and parents of pediatric patients often inquire about diet in relationship to atopic dermatitis, Dr. Greenberg offers a closer analysis of the data on this association. “A small minority of patients can experience flares...2021-01-2815 minDermatology WeeklyDermatology WeeklyBiologics for pediatric psoriasis and atopic dermatitisIn the news: Pityriasis rosea carries few risks for pregnant women Adjuvant nivolumab plus ipilimumab shows strong results in resected stage IV melanoma *  *  * Because psoriasis and atopic dermatitis (AD) can greatly affect quality of life in pediatric patients, the development of treatments with low-side effect profiles and less laboratory monitoring is essential. Vincent A. DeLeo, MD, talks to Amy S. Paller, MD, and Jennifer B. Scott, MD, about biologics approved for psoriasis and AD in the pediatric population. “Progressively, we’ve seen the newer biologics being more and more effective in both a...2021-01-2120 minDermatology WeeklyDermatology WeeklyHow to work up and treat vitiligo patients, plus news from the Medscape Live Pediatric and Women's Dermatology SeminarDermatology News: Beware a pair of dermatologic emergencies in children: https://bit.ly/37mGA2d Preadolescent acne: Management from birth requires increasing vigilance: https://bit.ly/34mCWn0   *  *  *   Managing vitiligo can be difficult for both patients and physicians. In this episode, guest host Seemal R. Desai, MD, (@SeemalRDesaiMD) talks to Pearl E. Grimes, MD, about how to better classify vitiligo disease status and parameters that impact treatment choice. “There are some aspects of classification that are really key from a therapeutic as well as a prognostic perspective. The things that I look at on a day-t...2020-12-1730 minDermatology WeeklyDermatology WeeklyPediatric procedural dermatology plus, CDC shortens quarantine and ‘Impressive’ results with neoadjuvant T-VEC in advanced melanomaDermatology News: International expert group agrees on redefining psoriasis severity https://bit.ly/3a6a7PJ ‘Impressive’ results with neoadjuvant T-VEC in advanced melanoma: https://bit.ly/39UEwA3 CDC shortens COVID-19 quarantine time to 10 or 7 days, with conditions: https://bit.ly/3qGIGSn *  *  * Procedural interventions in pediatric patients require special tools. Vincent A. DeLeo, MD, talks to Craig N. Burkhart, MD, MS, MPH, about dermatologic procedures in children, such as laser treatment of birthmarks or excisional mole removal. When considering general anesthesia use in children, Dr. Burkhart reflects that, “if [the patient is] a child that sit...2020-12-1017 minDermatology WeeklyDermatology WeeklyDerm Residents: Nail unDerm Residents: Nail unit squamous cell carcinoma; and merino wool for atopic derm and tildrakizumab is durableit squamous cell carcinoma; and merino wool for atopic derm and tildrakizumab is derableDermatology News: Merino wool clothing improves atopic dermatitis, studies find: https://bit.ly/3fFHQQI Tildrakizumab for psoriasis shows durable efficacy over 5 years: https://bit.ly/3l1Z0c9 AMA takes on vaccine misinformation, physician vaccines, racism: https://bit.ly/33ee0O2 *  *  * Nail unit squamous cell carcinoma (SCC) is difficult to diagnose or suspect clinically because of its tendency to present as nonspecific nail plate changes. The tumors usually are painless and asymptomatic, leading to a delay in diagnosis. In this resident takeover, Daniel R. Mazori, MD, talks to Mohammed Dany, MD, PhD, about nail unit SC...2020-11-2622 minDermatology WeeklyDermatology WeeklyHealth disparities brought to light by COVID-19, plus a hospital at home for COVID patientsDermatology News: Low threshold to biopsy atypical lesions may ID vulvar melanoma early, experts say https://www.mdedge.com/dermatology/article/231855/gynecologic-cancer/low-threshold-biopsy-atypical-lesions-may-id-vulvar Chronic inflammatory diseases vary widely in CHD risk https://www.mdedge.com/dermatology/article/231815/cad-atherosclerosis/chronic-inflammatory-diseases-vary-widely-chd-risk ‘Hospital at home’ increases COVID capacity in large study https://www.mdedge.com/dermatology/article/232113/coronavirus-updates/hospital-home-increases-covid-capacity-large-study   The COVID-19 pandemic has brought many longstanding health disparities to the forefront, particularly within the field of dermatology. In this episode, Candrice R. Heath, MD (@DrCandriceHeath) talks to Susan C. Taylor, MD, and Lynn McKinley-Grant, MD, a...2020-11-1943 minBlood & CancerBlood & CancerHow to kill a trialThe Tomosynthesis Mammography Imaging Screening Trial (TMIST) was designed to see if 3-D mammography, or tomosynthesis, could help personalize screening and if 3-D is actually better than the less expensive 2-D mammography. TMIST is the largest breast cancer screening trial in the United States, with a cost of $100 million and a planned enrollment of 165,000 women. There's just one problem. The study is falling short on enrollment of patients and participating sites. Will this mean the death of TMIST? For more details, see coverage of TMIST on Medscape: NCI May 'Kill' Major Mammography...2020-11-1707 minPsychcastPsychcastHave we lost too much?In this week's installment of Clinical Correlation, Renée Kohanski, MD, ponders the loss of professional courtesy and the larger implications of medicine-shifting paradigms. Clinical Correlation is a bi-monthly drop on the Psychcast feed. You can email the show at podcasts@mdedge.com, and you can learn more about MDedge Psychiatry here: https://www.mdedge.com/podcasts/psychcast.2020-11-1608 minPsychcastPsychcastBrain imaging, ‘neuropolarization,’ and why it’s so difficult to bridge the partisan divide with Dr. Yuan Chang Leong*** There is a transcript available for this episodes at https://www.medscape.com/viewarticle/940969 Yuan Chang Leong, PhD, spoke with Psychcast host Lorenzo Norris, MD, about his research into the neural underpinnings of right- and left-leaning individuals. Dr. Leong is a postdoctoral scholar in cognitive neuroscience at the University of California, Berkeley. He has no disclosures. Dr. Norris has no disclosures. Take-home points Dr. Leong and colleagues looked for further evidence of “neural polarization,” which is defined as divergent brain activity based on conversative versus liberal political attitudes. The prefrontal cort...2020-11-0428 minPsychcastPsychcastGetting to "No" you |Clinical CorrelationRenee Kohanski, MD, discusses managing difficult referrals from trusted colleagues. Clinical Correlation is a bi-monthly drop on the Psychcast feed. You can email the show at podcasts@mdedge.com, and you can learn more about MDedge Psychiatry here: https://www.mdedge.com/podcasts/psychcast.  2020-11-0209 minDermatology WeeklyDermatology WeeklyGuidelines for using phototherapy in psoriasis patients; plus, women in pediatric dermatologyDermatology News: Non-Whites remain sorely underrepresented in phase 3 psoriasis trials (https://bit.ly/3jmv2ia) Women make progress in pediatric dermatology leadership (https://bit.ly/35nNdir) Survey: Doctors lonely, burned out in COVID-19 (https://bit.ly/3dKwhXg)   *  *  * Psoriasis patients who are pregnant or those seeking a medication-free treatment may benefit from phototherapy. Vincent A. DeLeo, MD, talks to George Han, MD, PhD, and Jashin J. Wu, MD, about the joint guidelines from the American Academy of Dermatology and National Psoriasis Foundation for psoriasis treatment with phototherapy. They provide tips for...2020-10-2226 minPsychcastPsychcastProfessional passive aggression|Clinical CorrelationDr. Renee Kohanski discusses how important personal and professional development is among physicians in the workplace. Is your current job worth it? Clinical Correlation is a bi-monthly drop on the Psychcast feed. You can email the show at podcasts@mdedge.com and you can learn more about MDedge Psychiatry here: https://www.mdedge.com/podcasts/psychcast  2020-10-1909 minDermatology WeeklyDermatology WeeklyLooking back on retinoid discovery and development with Dr. James LeydenIn this week’s podcast, Dermatology News columnist Leslie S. Baumann, MD, interviews James J. Leyden, MD, emeritus professor of dermatology at the University of Pennsylvania, Philadelphia, about his significant ​research contributions in the field of dermatology, including finding the cure for diaper rash and the development of retinoids for acne and photoaging. Dr. Leyden also recounts his experience working with Albert Kligman, MD, at the University of Pennsylvania and how they changed the way the world treats acne with lots of contemplation, observation, perseverance, and a little luck. *  *  * 1. The interesting history of dermatologist-developed skin care ...2020-10-1547 minBlood & CancerBlood & CancerTERAVOLT registry sheds light on characteristics, treatment, and outcomes of patients with thoracic cancers and COVID-19How do patients with thoracic cancers fare when they develop COVID-19? The researchers behind the TERAVOLT registry are trying to find out. TERAVOLT investigator Alessio Cortellini, MD, of the University of L’Aquila (Italy), joined host David Henry, MD, to discuss the TERAVOLT registry and its findings, which were recently presented at the European Society for Medical Oncology Virtual Congress 2020. What is TERAVOLT? TERAVOLT is an international registry of patients with thoracic cancers and COVID-19 that was launched in March 2020 by Marina Garassino, MD, of the National Cancer Institute of Milan. The registry enrolls pa...2020-10-1520 minPsychcastPsychcastDogs in the time of face masks|Clinical CorrelationDr. Renee Kohanski, MD, uses a proverb to discuss how she talks to patients about face masks, and how she talks to patients with face masks on. What's hiding behind the mask? *  *  * Clinical Correlation is a bi-monthly drop on the Psychcast feed. You can email the show at podcasts@mdedge.com and you can learn more about MDedge Psychiatry here: https://www.mdedge.com/podcasts/psychcast  2020-10-0508 minDermatology WeeklyDermatology WeeklyRegulation of apps most frequently used by residentsDermatology News: Review finds evidence for beta-blockers for some rosacea symptoms (https://bit.ly/3kX91rB) Source:  https://bit.ly/2HKWJUX 2019 review: https://bit.ly/36jWvOL Conservative parameters key to maximizing cosmetic laser results in skin of color (https://bit.ly/33dIhNn) Source: https://bit.ly/3jiLcd8 J&J’s one-shot COVID-19 vaccine advances to phase 3 testing (https://bit.ly/33e07Qs) *  *  * Dermatology residents are utilizing apps for up-to-date and accurate information. Vincent A. DeLeo, MD, talks to Orit Markowitz, MD, and medical student Cynthia Chan about the regulation of mobil...2020-10-0127 minBlood & CancerBlood & CancerStudying cancer patients with COVID-19: Dr. Brian Rini describes the NCCAPS and CCC19 studies and reviews the latest findingsHow do patients fare when they have cancer and COVID-19? Researchers developed the COVID-19 and Cancer Consortium (CCC19) and the National Cancer Institute COVID-19 in Cancer Patients Study (NCCAPS) to gain some insight. In this episode, Brian Rini, MD, a professor of medicine at Vanderbilt University Medical Center, Nashville, Tenn., and host of The Uromigos podcast, explains what CCC19 and NCCAPS are. He also discusses findings from CCC19 that were presented at the European Society of Medical Oncology Virtual Congress 2020. NCCAPS (NCT04387656) NCCAPS is a natural history study of COVID-19 in patients with active...2020-09-2423 minDermatology WeeklyDermatology WeeklyHow to study in dermatology residencyEpisode 82 Dermatology News: Biologics for psoriasis may also reduce coronary plaque (https://bit.ly/3ckjVEK) Journal article: https://bit.ly/3mRW2JE Three-step approach may help relieve one of the itchiest vulvar conditions (https://bit.ly/33TeGI3) Many Americans still concerned about access to health care (https://bit.ly/33TeGI3) Survey: https://bit.ly/3kO0DdF *  *  * Dermatology residents identify studying as one of the main culprits leading to burnout during residency. In this resident takeover, Daniel R. Mazori, MD, talks to Sophie A. Greenberg, MD, (@sophiegreenberg) about the firehose of information th...2020-09-2440 minBlood & CancerBlood & CancerMedical school in the COVID era: Two RCSI students explain how the pandemic has affected themHow has COVID-19 impacted medical students? Two students from Royal College of Surgeons in Ireland (RCSI), Dublin, describe their experiences in this episode. Evani Patel and Sarah Chen, both second-year medical students at RCSI, tell host David H. Henry, MD, how the COVID-19 pandemic has shaped their educational experience thus far. Now, the pandemic has shifted the students’ education to a mix of virtual and in-person learning at RCSI, but COVID-19 also impacted the pair’s summer studentships at University of Pennsylvania, Philadelphia. Typically, the studentships involve seeing patients, attending lectures, and completing proj...2020-09-1729 minDermatology WeeklyDermatology WeeklyCosmetic procedures are back, plus COVID-19 expenses get billing codes and burnout is up and income is downAs lockdown restrictions are lifted, many dermatologists are resuming elective cosmetic procedures. Candrice Heath, MD, (@DrCandriceHeath) talks to Anthony M. Rossi, MD, (@DrAnthonyRossi) about the procedures patients are seeking while they have downtime as well as how physicians can safely treat these patients and conduct follow-up. They also discuss the prevalence of mask acne, known as “maskne,” during the pandemic. “We’re starting to put people on these acne regimens again. ... People who haven’t dealt with acne in a while or really never had it, we have to be putting them on a retinoid, a good skin regimen, because of...2020-09-1720 minBlood & CancerBlood & CancerHow I treat MDS: Dr. Shannon McCurdy talks prognostic scoring, ESAs, HMAs, transplant, and moreTreatment strategies for myelodysplastic syndromes (MDS) vary widely depending upon patients’ prognosis. In this episode, Shannon R. McCurdy, MD, of the University of Pennsylvania, Philadelphia, joined host David H. Henry, MD, to discuss how she treats patients with MDS. To start, Dr. McCurdy evaluates patients using the revised International Prognostic Survival Scale (IPSS-R), which can predict the aggressiveness of MDS. Low IPSS-R scores (6) are associated with high-risk MDS, which has a median survival of 0.8 years. Dr. McCurdy also performs molecular testing to assess risk. A poor-risk molecular profile can increase the IPSS-R by 1 point, she sa...2020-09-1031 minPsychcastPsychcastAnnouncing a new spinoff from the Psychcast: Clinical Correlation with Dr. Renee KohanskiPsychcast host Lorenzo Norris, MD, meets Renee Kohanski, MD, to announce the launch of Clinical Correlation. In Clinical Correlation, which will be released every other Monday, starting Sept. 14, Dr. Kohanski will expand on her “Dr. RK” segment and explore issues of interest to the practicing psychiatrist. And later, we will revisit four of Dr. Kohanski’s “Best of” segments. Next week, Dr. Norris will return with an interview with Peter Yellowlees, MD, about clinicians’ embrace of telepsychiatry during the pandemic. They also discuss whether many of the COVID-19–related changes – including those tied to reimbursement – are here to stay.2020-09-0227 minBlood & CancerBlood & CancerHem-Onc News: Aspirin linked to cancer progression in older adults, inhibitor could 'alter landscape' of RET+ tumors, and Black-White gap closingMDedge Hematology-Oncology news for the first week of September 2020.  Aspirin may accelerate cancer progression in older adults: https://bit.ly/2ENHRUc ASPREE trial: https://bit.ly/2QAsMYW Meta-analysis: https://bit.ly/2D6rXnl AsCaP: https://bit.ly/2G06X2I Black/White gap gone: ‘The only cancer where this has happened’: https://bit.ly/3jm8PBm Source: https://bit.ly/3lv4u0m Selpercatinib 'poised to alter the landscape' of RET+ cancers: https://bit.ly/34PYSbs Lung cancer results: https://bit.ly/3gB1FY7 Thyroid cancer results: https://bit.ly/2EHhCz5 Study confi...2020-09-0114 minBlood & CancerBlood & CancerSECURE-SCD: A registry of patients with sickle cell disease and COVID-19The SECURE-SCD registry was designed to collect and disseminate information on patients with sickle cell disease (SCD) who develop COVID-19. Two of the registry’s organizers are Amanda Brandow, DO, and Julie Panepinto, MD, both of the Medical College of Wisconsin/Children’s Wisconsin in Milwaukee. In this episode, Dr. Brandow and Dr. Panepinto discuss SECURE-SCD and its findings with host David H. Henry, MD. SECURE-SCD is an online registry that was launched in March 2020. On the registry’s website (https://covidsicklecell.org/), health care providers can submit deidentified data on patients with COVID...2020-08-2719 minBlood & CancerBlood & CancerDiabetes + weight loss could mean a higher risk of pancreatic cancer, digital breast tomosynthesis vs digital mammography, and adjuvant chemo is beneficial for some with low-grade gliomaNews for the week of August 24, 2020.  Beyond baseline, DBT no better than mammography for dense breasts: https://bit.ly/2FTRnpp Study source: https://bit.ly/2FTLkkI Lead author: https://bit.ly/3graAv0 Subgroups predict adjuvant chemoradiotherapy benefits in low-grade glioma: https://bit.ly/31oHkkr Source: https://bit.ly/3aSVe1j Diabetes plus weight loss equals increased risk of pancreatic cancer: https://bit.ly/2Etmbws Source: https://bit.ly/2EyRBkV For more MDedge podcasts: htttps://www.mdedge.com/podcasts Email the show: podcasts@mdedge.com2020-08-2509 minBlood & CancerBlood & CancerISTH 2020: Dr. Hanny Al-Samkari talks VTE in COVID-19, bevacizumab in HHT, and predisposition to thrombosis in NSCLCHanny Al-Samkari, MD, joins the podcast to discuss thrombosis in COVID-19 and lung cancer patients as well as the use of bevacizumab in patients with hereditary hemorrhagic telangiectasia (HHT). Dr. Al-Samkari, of Massachusetts General Hospital, presented three studies on these topics at the virtual ISTH 2020 Congress. In this episode, Dr. Al-Samkari describes these studies to host David H. Henry, MD. Thrombosis, Bleeding, and the Effect of Anticoagulation on Survival in Critically Ill Patients with COVID-19 in the United States This 67-center study included 3,239 critically ill adults with COVID-19. The 14-day incidence of radiographically confirmed venous thromboembolism...2020-08-1332 minBlood & CancerBlood & CancerHow I treat multiple myeloma: Dr. Gustavo Fonseca talks triple-agent therapy, transplant, and treatment failureHow does the community oncologist treat multiple myeloma? Gustavo A. Fonseca, MD, of Florida Cancer Specialists, shares his approach to myeloma treatment with host David H. Henry, MD. At the start of this episode, Dr. Fonseca and Dr. Henry discuss their love of podcasts, mentioning shows that have proven useful to them personally and professionally. The pair then move on to discuss hypothetical myeloma cases and advances in treatment. They cover triple-agent therapy, transplant, and bone-modifying agents. They also discuss the management of anemia, what to do after treatment failure, and how far myeloma treatment...2020-08-0631 minBlood & CancerBlood & CancerBeyond the lungs: How COVID-19 affects the blood, brain, gastrointestinal system, and other organ systemsCOVID-19 can have a negative impact on systems throughout the body, beyond just the lungs, according to a review published in Nature Medicine. Two authors of the review joined host David H. Henry, MD, to discuss their article, “Extrapulmonary manifestations of COVID-19.”  Aakriti Gupta, MD, of Columbia University Irving Medical Center, and Kartik Sehgal, MD, of Dana Farber Cancer Institute, discussed: ACE2, the entry receptor for SARS-CoV-2 Neurologic and gastrointestinal manifestations of COVID-19 Mechanisms of coagulation and thromboprophylaxis COVID-19 in cancer patients The impact of quarantine on cardiology patients The lasting effects of COVID-19 and the need...2020-07-3037 minBlood & CancerBlood & CancerMDedge Hematology|Oncology Journal Club 01 - All about breast cancer: Lumpectomy margins, partial vs whole breast irradiation, locoregional management after neoadjuvant chemo While relaxing on the Jersey Shore, host and MDedge Hematology/Oncology Editor-in-Chief, David Henry, MD, dove into the July 10, 2020, issue of the Journal of Clinical Oncology. In episode 82, we do the same.   J Clin Oncol. 2020 Jul 10. 38(20). 2217-2361. (https://bit.ly/2ZQEJ27)   You can follow along with the following articles: Lumpectomy Margins for Invasive Breast Cancer and Ductal Carcinoma in Situ: Current Guideline Recommendations, Their Implications, and Impact (https://bit.ly/39m5P3W) Accelerated Partial Breast Irradiation and Intraoperative Partial Breast Irradiation: Reducing the Burden of Effective Breast Co...2020-07-2324 minBlood & CancerBlood & CancerRTL 02 -- The latest news from MDedge Hematology/Oncology: MRI IDs significant prostate cancer, drug interactions to avoid in GI cancers, ctDNA clearance tracks with NSCLC survival, COVID symptoms persistThe latest news from MDedge Hematology/Oncology:  In this episode:  MRI reliably identifies significant prostate cancer * Original MDedge article (https://bit.ly/3hgKT1h) * PROMIS analysis (https://bit.ly/3fLOiEN) Drug-drug interactions to avoid in patients with GI cancer * Original MDedge article (https://bit.ly/39eHi0G) ctDNA clearance tracks with PFS in NSCLC subtype * Original MDedge article (https://bit.ly/3eJKm6o) * Abstract from AACR 2020 (https://bit.ly/30uQQ3R) * TATTON results in The Lancet Oncology (https://bit.ly/3jq1L7J) COVID-19 symptoms can linger for months * Or...2020-07-2112 minBlood & CancerBlood & CancerCancer and diet: Dr. Dawn Lemanne talks fasting, IGF-1, and blood sugarCancer patients often ask what they should eat, but it’s just as important to know when they should eat, according to Dawn Lemanne, MD, of Oregon Integrative Oncology, Ashland, and the University of Arizona, Tucson. Dr. Lemanne tells host David H. Henry, MD, how cancer patients may benefit from fasting. The pair discuss immune system suppression, insulinlike growth factor I (IGF-I), and blood glucose monitoring. Fasting and the immune system Fasting before and after chemotherapy can put part of the immune system “to sleep,” thereby protecting it from the deleterious effects of treatment, Dr. Le...2020-07-1623 minBlood & CancerBlood & CancerEarlier lung screening doubles eligibility, lifestyle reduces breast cancer risk regardless of genetics, FDA approves MDS/CMML drug, COVID mask exemptions The latest news for hematology and oncology professionals. In this episode:  USPSTF: Earlier lung cancer screening can double eligibility * Review and comment on the USPSTF site: https://bit.ly/3fppiD7* National Lung Screening Trial https://bit.ly/2CvNRQt  Lifestyle choices may reduce breast cancer risk regardless of genetics* Read the article on MDedge: https://bit.ly/2ZrsWqN * Read the original research: https://bit.ly/3etRLGx (JAMA Netw Open. 2020;3(4):e203760). FDA approves oral therapy for myelodysplastic syndromes, CMML * Read the FDA news release: https://bit.ly/2WeUIVb 2020-07-1411 minBlood & CancerBlood & CancerPersonal and professional impact of COVID-19 - diary of an oncologistOncologist Don S. Dizon, MD, joins the podcast to discuss how the COVID-19 pandemic has affected him personally and professionally. Dr. Dizon is the director of women’s cancers at Lifespan Cancer Institute and director of medical oncology at Rhode Island Hospital, both in Providence. Dr. Dizon tells host David H. Henry, MD, how COVID-19 affected his patients, colleagues, and research as well as his personal life. Dr. Dizon chronicled some of these developments in a series of columns published on Medscape. Disclosures: Dr. Dizon has relationships with Regeneron, Astra-Zeneca, Clovis, Bristol-Myers Squibb, an...2020-07-0919 minBlood & CancerBlood & CancerPatient anxiety, social support, optimism bias, and 'How long do I have left?': The best-of Dr. Ilana Yurkiewicz Ilana Yurkiewicz, MD, recorded dozens of Clinical Correlation segments for Blood & Cancer for more than a year. She also hosted a three-part series on difficult conversations that trainees have with their patients. In this episode, we revisit the best of Dr. Yurkiewicz.   'How long do I have left?' 02:59 Anxiety 17:02 Optimism Bias 20:21 Social Support 23:51 Family Dynamics 26:07 For more MDedge Podcasts, go to mdedge.com/podcasts Email the show: podcasts@mdedge.com Interact with us on Twitter: @MDedgehemonc David Henry on Twitter: @davidhenrymd2020-07-0229 minPsychcastPsychcastThe ‘best of’ COVID-19: Dr. Sheldon Preskorn on educating patients about coronavirus, Dr. Jay Shore on using telepsychiatry, and Dr. Lynne Gots on using CBT to help patients with anxietyThis week, we decided to revisit three of the Psychcast episodes that examined various aspects of COVID-19. First, you will hear excerpts from the interview that host Lorenzo Norris, MD, did with Sheldon H. Preskorn, MD, on educating patients about SARS-CoV-2 and the disease. Next, Jay H. Shore, MD, MPH, conducts a Masterclass lecture on factors to consider while using telepsychiatry during the pandemic. And later, guest host Jacqueline Posada, MD, talks with Lynne S. Gots, PhD, about using cognitive-behavior therapy to treat patients with anxiety. *  *  * For more MDedge Podcasts, go to mdedge.co...2020-07-0132 minBlood & CancerBlood & CancerDrugs FDA-approved for hematology / oncology in 2020: ‘Game-changing’ and ‘niche’ indicationsThe Food and Drug Administration has approved dozens of drugs for new hematology/oncology indications this year. Host David Henry, MD, was joined by David Mintzer, MD, and other colleagues at Penn Medicine in Philadelphia – Justine Cohen, DO, and Ingrid Kohut, DO – to discuss some of these approvals. Dr. Mintzer reviewed: The “game-changing” approval of niraparib (Zejula) in advanced ovarian, fallopian tube, or primary peritoneal cancer. The “exciting” approval of sacituzumab govitecan-hziy (Trodelvy) in metastatic triple-negative breast cancer. The “COVID-relevant” approval of a new dosing regimen for pembrolizumab (Keytruda) – 400 mg every 6 weeks – across all approved adult indications. The “ni...2020-06-1829 minBlood & CancerBlood & CancerNon–small cell lung cancer: How to choose the best therapy and reviewing the first virtual ASCOJack West, MD, joins the podcast to discuss how he chooses first-line treatment in new patients with non–small cell lung cancer (NSCLC). Dr. West is an associate clinical professor in medical oncology at City of Hope Comprehensive Cancer Center in Duarte, Calif., and a thought leader in thoracic oncology. Dr. West also explores how the COVID-19 pandemic influences treatment approaches, the usefulness of liquid biopsy, and how he weighs the potentially higher risk for COVID-19 complications from checkpoint inhibitors.   Check out Dr. West’s last two appearances on the podcast: https://www.mdedge.com/p...2020-06-0435 minBlood & CancerBlood & CancerVTE rate, "COVID toes," and Virchow's triad: What you need to know about COVID and coagulationAdam C. Cuker, MD, joins host David H. Henry, MD, to discuss recent findings regarding coagulation in COVID-19 patients. Both Dr. Cuker and Dr. Henry both practice at the Hospital of the University of Pennsylvania in Philadelphia. Dr. Cuker cited data suggesting at least 25%-30% of patients with COVID-19 develop venous thromboembolism (VTE), despite receiving prophylactic anticoagulation. Furthermore, COVID-19 patients have presented with “lots of different thrombotic manifestations,” he said. This includes stroke and “COVID toes syndrome,” a condition in which patients present with ischemic toes, which appears to have a thromboembolic etiology. Dr. Cuker suggeste...2020-05-2132 minBlood & CancerBlood & CancerAn internist’s experience with COVID-19In this episode, Matthew Watto, MD, an internist at Pennsylvania Hospital in Philadelphia, tells host David H. Henry, MD, also of Pennsylvania Hospital, how the COVID-19 pandemic has affected him personally and professionally. Dr. Watto recounts how COVID-19 has impacted patient volume, shifts, teaching, and interactions between patients and staff. Dr. Watto also discusses his internal medicine podcast, The Curbsiders, which, he says, provides listeners with “clinical pearls, practice-changing knowledge, and bad puns.” Disclosures: Dr. Henry has no financial disclosures relevant to this episode. Dr. Watto has no financial disclosures relevant to this epis...2020-05-1431 minBlood & CancerBlood & CancerTreating genitourinary malignancies in the COVID-19 eraHow should oncologists be treating genitourinary malignancies during the COVID-19 pandemic? Aly-Khan A. Lalani, MD, of McMaster University in Hamilton, Ontario, and colleagues recently published recommendations that help answer that question (Can Urol Assoc J. 2020 May;14[5]:e154-8). In this episode, Dr. Lalani reviews some of these recommendations with podcast host David H. Henry, MD, of Pennsylvania Hospital in Philadelphia. The pair discuss when and how to use androgen receptor axis-targeted therapies and radium-223 in metastatic prostate cancer, platinum-based chemotherapy in advanced urothelial carcinoma, and checkpoint inhibitors in patients with urothelial carcinoma or renal cell carcinoma. 2020-05-0734 minBlood & CancerBlood & CancerThe first virtual ASCO meeting; plus Part 2 of tech tools for docsThe American Society of Clinical Oncology is gearing up for its first-ever virtual meeting at the end of May 2020. ASCO’s president Howard A. “Skip” Burris, III, MD, joins David H. Henry, MD, of Pennsylvania Hospital, Philadelphia, to explain how the virtual meeting will work, from releasing research to earning continuing medical education credits. Dr. Burris also explores how the society is responding to COVID-19. Later in the podcast, Bernard A. Mason, MD, an oncologist with Pennsylvania Hospital and the University of Pennsylvania, both in Philadelphia, is back with some bonus technology tips for taking notes and syncin...2020-04-3037 minBlood & CancerBlood & CancerTreating colorectal cancer in the COVID-19 eraOncologists are now weighing the benefits of treating cancer patients against the risk of exposing them to SARS-CoV-2. David Kerr, MD, DSc, of University of Oxford (England) talks with podcast host David H. Henry, MD, of Pennsylvania Hospital in Philadelphia, about how to treat colorectal cancer patients in the COVID-19 era. Dr. Kerr cowrote an article on MDedge Hematology/Oncology that outlined recommendations for treating colorectal cancer patients during the pandemic. In this episode, Dr. Henry and Dr. Kerr review those recommendations and compare notes on U.K. and U.S. practices. Disclosures: ...2020-04-2339 minBlood & CancerBlood & CancerCOVID-19 and the community oncologistHow are community oncologists adapting to the COVID-19 pandemic? Podcast host David H. Henry, MD, of Pennsylvania Hospital in Philadelphia, explores this question with Matthew Lonergan, MD, of Willamette Valley Cancer Institute (WVCI) and Research Center in Eugene, Ore. Dr. Lonergan explains how WVCI is attempting to minimize staff exposure to COVID-19, how physicians there are dealing with the transition to telemedicine, and how a lack of resources has affected WVCI. Dr. Lonergan and Dr. Henry also discuss how the COVID-19 pandemic has changed research, tumor boards, and other meetings. And the pair compare the response to...2020-04-1638 minBlood & CancerBlood & CancerCOVID-19 and lung cancer: The decision to delay treatmentIn the “new normal” of treating cancer patients during COVID-19, when do you decide to start treatment or pause it? Narjust Duma, MD, a thoracic oncologist at the University of Wisconsin, Madison, shares how she makes those decisions in partnership with her lung cancer patients and how the discussions are complicated by the fear and uncertainty around the pandemic. Later in the podcast, Dr. Duma and podcast host David H. Henry, MD, of Pennsylvania Hospital, Philadelphia, explore how telehealth changes patient encounters, use of liquid biopsies to keep patients out of the hospital, and the importance of chec...2020-04-0933 minBlood & CancerBlood & CancerCOVID-19: ‘The world has changed’Zainab Shahid, MD, medical director of bone marrow transplant infectious diseases at the Levine Cancer Institute/Atrium Health in Charlotte, N.C., breaks down when cancer patients should seek testing for COVID-19 and how they should be treated. Dr. Shahid also compares notes with Blood & Cancer host David H. Henry, MD, of Pennsylvania Hospital in Philadelphia, on how the COVID-19 pandemic has changed the world of medical education. In Clinical Correlation, Ilana Yurkiewicz, MD, of Stanford (Calif.) University, celebrates National Doctors Day amid the COVID-19 pandemic. Topics covered in this podcast: How the education...2020-04-0231 minBlood & CancerBlood & CancerGrands rounds in the age of COVID-19; cardiotoxicity in breast cancerSusan Dent, MD, codirector of the cardio-oncology program at Duke University in Durham, N.C., reflects on virtual grand rounds, telehealth, the screening of patients before clinic visits, and other new realities of cancer care in the age of COVID-19. Dr. Dent also discusses the importance of assessing breast cancer patients for cardiotoxicity. In Clinical Correlation, Ilana Yurkiewicz, MD, of Stanford (Calif.) University, talks about the importance of advance directives. *  *  *   Cardiotoxicity in breast cancer treatment HER2 drugs (such as trastuzumab) and conjugates If given appropriately, these drugs have limited cardiotoxicity. The...2020-03-2632 minBlood & CancerBlood & CancerTech tools for docs: Apps, sites, and software in the virtual worldDavid Henry, MD, welcomes Bernard A. Mason, MD, to discuss Dr. Mason's favorite digital tools for working as a physician in part 1 of 2. Dr. Mason is an oncologist with the Pennsylvania Hospital and the University of Pennsylvania, both in Philadelphia.  Dr. Mason explains the actual benefits for doctors and health care providers for popular apps and services from storage to maps. He and Dr. Henry explore the following: One drive Google Drive Google Photos Google Maps Offline HERE WeGo This week's installment of Clinical Correlation, Ilana Yurkiewicz, MD, poses a complicated question about o...2020-03-1932 minBlood & CancerBlood & CancerTreatment approaches in AMLA diagnosis of acute myeloid leukemia (AML) was once an emergency, requiring immediate treatment. Today, the need to start treatment is still urgent, but many patients can benefit by waiting a few days for testing to reveal a fuller picture of the disease. That’s the advice of James M. Foran, MD, of the Mayo Clinic. He joins Blood & Cancer host David H. Henry, MD, of the Pennsylvania Hospital, Philadelphia, to walk through some patient scenarios and the newest treatment options. In Clinical Correlation, Ilana Yurkiewicz, MD, of Stanford (Calif.) University, talks about what patients do and do...2020-02-2732 minBlood & CancerBlood & CancerTreatment tips in CLLThe million-dollar question in the treatment of chronic lymphocytic leukemia (CLL) is what to do after a patient relapses following treatment with venetoclax. Anthony Mato, MD, and Lindsey Roeker, MD, both of Memorial Sloan Kettering in New York, join podcast host David H. Henry, MD, of Pennsylvania Hospital, Philadelphia, to explore the evidence about this question and to review the initial patient work-up and treatment strategies. In Clinical Correlation, Ilana Yurkiewicz, MD, of Stanford (Calif.) University, discusses patients compliance and how clinician biases can influence compliance. Practice points: For patients with CLL with unmutated...2020-02-2022 minBlood & CancerBlood & CancerWhen to refer for CAR T-cell therapyChimeric antigen receptor (CAR) T-cell therapy is one of the hottest advances in lymphoma treatment, but who should get it and what does the process look like? Allison Winter, MD, of the Cleveland Clinic helps answer those questions on the podcast. She joins Blood & Cancer host David H. Henry, MD, of the Pennsylvania Hospital, Philadelphia, to break down the side effects and look ahead to possible off-the-shelf products. In Clinical Correlation, Ilana Yurkiewicz, MD, of Stanford (Calif.) University, discusses optimism bias. She recalls a time when a patient’s drive for optimism affected what she told them an...2020-02-1321 minPsychcastPsychcast‘Lived experience’ with suicidality with Dr. Lynes and Dr. MyersWilliam Lynes, MD, joins guest host Michael F. Myers, MD, to discuss his struggles with medical and psychiatric hardships, his suicidality, and the eventual suicide attempt that changed his life. Dr. Myers is professor of clinical psychiatry, State University of New York, Brooklyn. Dr. Lynes, a retired urologist, author, and speaker/advocate on physician burnout and suicide, divides his professional life into two distinct eras: 1987-1998, during which he had a successful practice and happy life, and after 1998, when he spiraled downward medically and psychiatrically. After meeting another physician with a similar experience who had...2020-02-1234 minBlood & CancerBlood & CancerUnderstanding biosimilarsThink of biosimilars as your mother’s minestrone soup: It’s the same recipe and ingredients every time, but not every batch is chemically identical, even if it tastes about the same. That’s how Brian T. Hill, MD, PhD, of the Cleveland Clinic, describes biosimilars. He joins Blood & Cancer host David H. Henry, MD, of Pennsylvania Hospital, Philadelphia, to discuss how biosimilars are made and approved, and how they differ from generic drugs.  In Clinical Correlation, Ilana Yurkiewicz, MD, of Stanford (Calif.) University, talks about percentages -- what they mean, what they don’t mean, and how they...2020-02-0619 minBlood & CancerBlood & CancerASH19 special reportBlood & Cancer takes you behind the podium at the American Society of Hematology annual meeting for an in-depth look at the latest developments in anemia and myelodysplastic syndrome, chimeric antigen receptor (CAR) T-cell therapy for mantle cell lymphoma, use of novel agents in follicular lymphoma, and a range of new advances being explored in chronic lymphocytic leukemia. Guests on the podcast include Brian T. Hill, MD, PhD, and Allison Winter, MD, both with the Cleveland Clinic, and Anthony Mato, MD, and Lindsey E. Roeker, MD, of Memorial Sloan Kettering Cancer Center in New York. Plus...2020-01-3030 minBlood & CancerBlood & CancerSickle cell update: Treating pain and progress toward cureWhen it comes to treating pain related to sickle cell disease, consider the underlying factors, from constipation to compression spine deformity. That’s just some of the advice from Ifeyinwa Osunkwo, MD, of Atrium Health and Levine Cancer Institute in Charlotte, N.C. She joins host David H. Henry, MD, of Pennsylvania Hospital, Philadelphia, to discuss her tips for treating pain and other complications of sickle cell disease. Dr. Osunkwo also provides an update on progress toward a cure in sickle cell disease that could be available to a large number of patients. Plus, in Clinical Correlation, Il...2020-01-2325 minBlood & CancerBlood & CancerPalliative care: Not just another word for hospiceThomas LeBlanc, MD, of Duke Cancer Institute in Durham, N.C., joins host David H. Henry, MD, of Pennsylvania Hospital, Philadelphia, to discuss the evolution of the palliative care field and some of the underrecognized ways that it can improve care for hematology-oncology patients. Plus, in Clinical Correlation, Ilana Yurkiewicz, MD, of Stanford (Calif.) University, shares the story of a patient who put aside her own desire for hospice because of family pressure to pursue curative treatment. *  *  * Palliative medicine has evolved tremendously over the past decade; it used to be synonymous with hospice and dy...2020-01-0934 minBlood & CancerBlood & CancerThe best of Clinical CorrelationIn this special edition podcast, we bring you the best of Clinical Correlation, a segment on the human side of hematology-oncology care. Clinical Correlation is written, recorded, and produced by Ilana Yurkiewicz, MD, of Stanford (Calif.) University. This episode includes five of our favorite Clinical Correlation segments.   For more MDedge Podcasts, go to mdedge.com/podcasts Email the show: podcasts@mdedge.com Interact with us on Twitter: @MDedgehemonc David Henry on Twitter: @davidhenrymd Ilana Yurkiewicz on Twitter: @ilanayurkiewicz2020-01-0215 minPsychcastPsychcastInflammation and mental illness revisited with Dr. Roger McIntyreLorenzo Norris, MD, and Roger McIntyre, MD, talk about obesity, inflammation, and mental illness. The conversation, which originally dropped a few months ago, took place at the Focus on Neuropsychiatry 2019 meeting. The meeting was sponsored by Current Psychiatry and Global Academy for Medical Education. The original podcast included robust Show Notes by Jacqueline Posada, MD. Also, you can watch the conversation between Dr. Norris and Dr. McIntyre on video or on YouTube. Later, Renee Kohanski, MD, talks about different ways to think about resolutions and behavioral change. For more MDedge Podcasts, go to m...2020-01-0130 minBlood & CancerBlood & CancerICYMI: Get to know Dr. Ilana YurkiewiczIn this special edition podcast, Blood & Cancer revisits an interview with Ilana Yurkiewicz, MD, of Stanford (Calif.) University. Dr. Yurkewicz is the writer and producer of the podcast’s Clinical Correlation segment, which puts a human face on hematology-oncology care. She sits down with MDedge producer Nick Andrews for a wide-ranging interview that covers everything from the best advice she’s ever gotten to her favorite science fiction writer. The interview first aired on our sister podcast, Postcall.   For more MDedge Podcasts, go to mdedge.com/podcasts Email the show: podcasts@mdedge.com 2019-12-2636 minPsychcastPsychcastBuilding resilience in rural communities with Dr. Caroline Bonham and Dr. Avi KriechmanIn this episode of the MDedge Psychcast, we revisit an interview that Lorenzo Norris, MD, MDedge Psychiatry editor in chief, conducted earlier this year by phone with two psychiatrists working in New Mexico. Dr. Norris spoke with Caroline Bonham, MD, and Avi Kriechman, MD, about enhancing resilience in rural communities. Dr. Bonham is vice chair in the department of psychiatry and behavioral sciences at the University of New Mexico, Albuquerque. Dr. Kriechman is assistant professor in that department, and a pediatrician who works on youth suicide prevention and school mental health.   Understanding risks o...2019-12-2525 minBlood & CancerBlood & CancerASCO president on uniting the oncology fieldHoward “Skip” Burris, MD, chief medical officer of Sarah Cannon Cancer Institute in Nashville, Tenn., joins the podcast to talk about what it’s like to be the 2019-2020 president of the American Society of Clinical Oncology. Dr. Burris joins Blood & Cancer host David H. Henry, MD, of Pennsylvania Hospital, Philadelphia, to share his priorities as president and how he finds the time for advocacy, research, and clinical practice. Plus, in Clinical Correlation, Ilana Yurkiewicz, MD, of Stanford (Calif.) University, shares the story of a couple who had cancer at the same time.   For mor...2019-12-1922 minBlood & CancerBlood & Cancer2019 drug approvals in hematology-oncologyDavid Mintzer, MD, of the University of Pennsylvania, Philadelphia, joins the podcast to discuss noteworthy drug approvals in hematology-oncology in 2019. Dr. Mintzer and Blood & Cancer host, David H. Henry, MD, of Pennsylvania Hospital, Philadelphia, discuss what these new treatment options mean for clinicians and patients. Plus, in Clinical Correlation, Ilana Yurkiewicz, MD, of Stanford (Calif.) University, is at the annual meeting of the American Society of Hematology with a reminder that the way we talk about patients matters. *  *  *  Help us make this podcast better! Please take our short listener survey: https://www.surveymonkey.com/r...2019-12-1221 minDermatology WeeklyDermatology WeeklyAAD 2019 Summer Meeting highlightsThis week’s episode features highlights of the AAD 2019 Summer Meeting.  Adam Friedman, MD, takes a closer look at nanotechnology from a dermatology perspective. Topical therapies often “have a very hard time getting to where they need to be, and nanotechnology, just by size alone, can really offer some unique benefits,” says Dr. Friedman, professor of dermatology and the interim chair of the dermatology department at George Washington University, Washington. Justin Ko, MD, director and chief of medical dermatology, Stanford (Calif.) Health Care, spoke with MDedge reporter Ted Bosworth about the use of augmented intelligence in derma...2019-11-2854 minPsychcastPsychcastLorenzo Norris, MD, and the Best of APA 2019This week, we are replaying five interviews that MDedge Psychiatry editor in chief Lorenzo Norris, MD, conducted at the 2019 American Psychiatric Association annual meeting. Dr. Norris spoke with Igor Galynker, MD, (Mount Sinai Beth Israel, N.Y.) about identifying suicide crisis syndrome; Jonathan M. Meyer, MD, (University of California, San Diego) about prescribing clozapine for treatment refractory schizophrenia; Robert M. McCarron, DO, (University of California, Irvine) about psychiatry and primary care; Cam Ritchie, MD, MPH, about preparing patients for disruptions in psychiatric medications; and Richard Balon, MD, (Wayne State University, Detroit) about overcoming resistance to prescribing benzodiazepines...2019-11-2734 minPostcall PodcastPostcall PodcastWords matter: Calling psychiatry patients by their diseaseMedical Muggle Nick Andrews and Emi Okamoto, MD, discuss a new survey about using the appropriate language when referring to patients. They also get into how banning sugary drinks went over at one California institution and talk about what physicians need to know about CBD.  *** Help us improve this podcast! Please click here to take this short listener survey: https://www.surveymonkey.com/r/podcastsurveyOct2019 *** The interview this week is with Elisabeth Poorman, MD, MPH. Dr. Poorman is a clinical instructor of medicine at the University of Washington, Seattle. ...2019-11-0845 minPsychcastPsychcastSuicide and the opioid crisis with Dr. Mark S. Gold  Mark S. Gold, MD, joins Lorenzo Norris, MD, host of the MDedge Psychcast and editor in chief of MDedge Psychiatry, to discuss the intersection between the rise in suicide and the opioid crisis in the United States. Dr. Gold is adjunct professor of psychiatry at Washington University in St. Louis. He also serves on the editorial advisory board of MDedge Psychiatry. Previously, Dr. Gold served as distinguished professor and chairman of the psychiatry department at the University of Florida, Gainesville. * * *  Help us make this podcast better! Please take this short listener su...2019-10-3044 minPostcall PodcastPostcall PodcastNo free medical adviceNick Andrews and Emi Okamoto, MD, talk about how to decrease the number of phone calls to your office, how more and more people view mental illness as a threat, and how to handle it when your family and friends ask for medical advice.  The interview this week is Taylor Brana, DO, the founder, producer, and host of the Happy Doc Podcast.  Timestamps: Is mental illness threatening? (01:58) Preview gender empowerment conversation (06:08) How to decrease your office phone calls (06:58) Should you charge your friends for medical advice? (09:25) Meet the guest (14:15) Interview (18:50) Links: People vi...2019-10-1844 minPostcall PodcastPostcall PodcastDrinking before a shift and hard patient conversationsIn episode 51, Nick and Emi Okamoto, MD, discuss what makes a good doctor-patient relationship, how EMRs affect burnout, and when, if ever, it's okay to have had a drink before a clinical shift.  The interview portion of this episode comes from Ilana Yurkiewicz, MD, who hosts a discussion about difficult conversations that residents and fellows need to have with their patients. Dr. Yurkiewicz, along with Emily Bryer, DO, and Ronak Mistry, DO, address those times when a patient asks what you would do if the patient were your family member, and how much patients really want to k...2019-10-1132 minPsychcastPsychcastICYMI: Schizophrenia with Dr. Henry NasrallahHenry Nasrallah, MD, was the first-ever guest on the MDedge Psychcast. In a three-part series, he joined Lorenzo Norris, MD, host of the Psychcast and editor in chief of MDedge Psychiatry, to talk about schizophrenia. In this throwback episode, the three-part conversation has been edited together into one episode.  Part I: Etiology, presentation, and recent advances  Part II: Manifestations; treating early Part III: Treatment of first-episode schizophrenia In part I, Dr. Nasrallah and Dr. Norris talk about the etiology, presentation, and the recent advances in how schizophrenia is conceptualized. In part II, the two discuss the...2019-09-3022 minPsychcastPsychcastMental health disaster response with Dr. Judith MilnerJudith R. Milner, MD, MEd, SpecEd, joins Lorenzo Norris, MD, host of the MDedge Psychcast and editor in chief of MDedge Psychiatry, to talk about steps psychiatrists can take to address the mental health needs of people traumatized by a natural disaster, such as Hurricane Dorian survivors.  In This Week in Psychiatry, Katherine Epstein, MD, and Helen M. Farrell, MD, write about miracle cures in psychiatry. You can read the article online by clicking here or you can access the downloadable PDF by clicking here.  Time Stamps: This Week in Psychiatry (02:37) Interview with Dr. Mi...2019-09-1843 minPostcall PodcastPostcall PodcastPhysician suicide awareness; plus, can Groupon fix healthcare?National Suicide Prevention Week interview with Janae Sharp of the Sharp Index, which is a resource for physician suicide awareness, prevention, and research.  Emi Okamoto, MD, and Nick have a mini journal club about the med student perspective on suicide and burnout and how Groupon can save you and/or your patients money on some medical procedures.  Time stamps:  Journal Club (01:51) Groupon saves money (02:22) Trump administration moves to ban non-tobacco flavored e-cigarettes (08:00) Med student perspective on suicide (09:47) Interview introduction (14:02) Interview with Janae Sharp (17:51) Relevant links: Journal club articles Groupon (Medscape) Med stu...2019-09-1347 minPsychcastPsychcastDr. John Mann discusses suicide preventionShow Notes J. John Mann, MD, joins Lorenzo Norris, MD, host of the MDedge Psychcast and editor in chief of MDedge Psychiatry, to talk about the need for medicine to shift its approaches to preventing suicide. They spoke at the Focus on Neuropsychiatry 2019 meeting, sponsored by Current Psychiatry and Global Academy for Medical Education. Dr. Mann is professor of translational neuroscience at Columbia University in New York.  For a complete video of this interview, see this vodcast. Don’t miss the “Dr. RK” segment by Renee Kohanski, MD, who discusses how a relig...2019-09-0925 minPsychcastPsychcastDr. Roger McIntyre discusses the role of inflammation in mental illness  Show Notes Roger McIntyre, MD, joins Lorenzo Norris, MD, host of the MDedge Psychcast and editor in chief of MDedge Psychiatry, to talk about obesity, inflammation, and treatment implications for mental health conditions. They spoke at the Focus on Neuropsychiatry 2019 meeting, sponsored by Current Psychiatry and Global Academy for Medical Education.  Dr. McIntyre is a professor of psychiatry and pharmacology at the University of Toronto, and head of the mood disorders psychopharmacology unit at the University Health Network, also in Toronto. For a complete video of this interview, please visit the vo...2019-08-2832 minDermatology WeeklyDermatology WeeklyAugmented intelligence: An interview with Dr. Justin KoDr. Justin Ko speaks with MDedge reporter Ted Bosworth about the use of augmented intelligence in dermatology. Dr. Ko is the coauthor of the American Academy of Dermatology’s position statement on augmented intelligence, which was released in May 2019. Dr. Ko addressed this topic during the plenary session at the AAD’s summer meeting in New York City, in a presentation titled “Augmented intelligence: Fusing technology with human expertise to enhance dermatologic care.” “Augmented intelligence is a term that’s specifically used so that we can move people away from conceptions about artificial intelligence,” Dr. Ko explained i...2019-08-2218 minPsychcastPsychcastGun violence prevention: Dr. Jack Rozel returns  Show Notes Jack Rozel, MD, returns to the MDedge Psychcast to discuss gun violence and a new report from the National Council for Behavioral Health. In episodes 29 and 33, Dr. Rozel talked with Lorenzo Norris, MD, host of the MDedge Psychcast and editor in chief of MDedge Psychiatry, about this topic in the wake of the shooting last year at the Tree of Life synagogue in Pittsburgh.  Dr. Rozel is medical director of resolve Crisis Services at the Western Psychiatric Institute and Clinic of the University of Pittsburgh. He also is president-elect of the Am...2019-08-2151 minPsychcastPsychcastPsychcast meets PsychEdLorenzo Norris, MD, host of the MDedge Psychcast and editor in chief of MDedge Psychiatry, interviews the psychiatry residents who produce the PsychEd podcast, which as they put it, is “created by medical learners, for medical learners.” Dr. Norris speaks with some of the members of PsychEd podcast team: Sarah Hanafi, MD, a first-year resident in psychiatry at McGill University, Montreal; Alex Raben, MD, a fourth-year resident in psychiatry at the University of Toronto; Lucy Chen, MD, a fourth-year psychiatry resident at the University of Toronto; and Bruce Fage, MD, a fifth-year psychiatry resident at the University of T...2019-08-1447 minDermatology WeeklyDermatology WeeklyTreating pigmentary disorders; plus vitamin A and SCC, and nanotechnology in dermatology Seemal Desai, MD, talks with MDedge editor Elizabeth Mechcatie about the treatment of patients with pigmentary disorders in an interview at the summer meeting of the American Academy of Dermatology. We also bring you the latest in dermatology news and research: Higher dietary vitamin A linked to lower squamous cell carcinoma risk The results of the large prospective cohort study support the protective role of vitamin A against squamous cell carcinoma development. Adam Friedman, MD, takes a closer look at nanotechnology from a dermatology perspective. Ranking the best and...2019-08-0819 minPsychcastPsychcastEp 73Dr. Galynker Part II Show Notes Last week, Igor Galynker, MD, PhD, spoke with Lorenzo Norris, MD, host of the MDedge Psychcast and editor in chief of MDedge Psychiatry, about how to identify suicide crisis syndrome. This week, he explores the kinds of “gut feelings” that clinicians can access to help them identify when a patient might have the syndrome.   Dr. Galynker has been a guest on the Psychcast twice before, once to discuss the impact of suicide on physicians and a second time to talk about his research on the arguments for adding a suicide-specific diagnosis to the DSM-5...2019-08-0731 minPsychcastPsychcastEpisode 72 (Part I)  Show Notes Igor Galynker, MD, PhD, talks with Lorenzo Norris, MD, host of the MDedge Psychcast and editor in chief of MDedge Psychiatry, about suicide crisis syndrome.   Dr. Galynker has been a guest on the Psychcast twice before, once to discuss the impact of suicide on physicians and a second time to talk about his research on the arguments for adding a suicide-specific diagnosis to the DSM-5. He is associate chairman for research in the department of psychiatry at Mount Sinai Beth Israel in New York. In addition, Dr. Galynker is founder and di...2019-07-3139 minPsychcastPsychcastDr. Cam Ritchie on preparing patients for disruptions of psychiatric medicationsShow Notes Elspeth Cameron Ritchie, MD, MPH, talks with Lorenzo Norris, MD, host of the MDedge Psychcast and editor in chief of MDedge Psychiatry, about averting disruptions in psychiatric medications after short- and long-term disasters. Dr. Ritchie is a psychiatrist who works in Washington. Show Notes by Jacqueline Posada, MD, 4th-year resident in the department of psychiatry & behavioral sciences at George Washington University, Washington. Later, in the “Dr. RK” segment, Renee Kohanski, MD, discusses the potential impact of pharmacogenomics on the practice of psychiatry. Dr. Kohanski, a member of the MDedge Psyc...2019-07-2431 minPsychcastPsychcastOvercoming resistance to prescribing benzodiazepines for patients with serious medical illnessesEp. 70 Show Notes By Jacqueline Posada, MD, 4th-year resident in the department of psychiatry & behavioral sciences at George Washington University, Washington. In this episode, Richard Balon, MD, returns to the MDedge Psychcast to discuss benzodiazepines. This time, Lorenzo Norris, MD, host of the MDedge Psychcast and editor in chief of MDedge Psychiatry, interviewed Dr. Balon about prescribing benzodiazepines for patients with serious medical illnesses. They also examine some of the controversies around benzodiazepines and common mistakes that some clinicians make when prescribing these drugs. Dr. Balon is professor of psychiatry at W...2019-07-1727 minPsychcastPsychcastBest of: Suicide prevention  Show Notes In this episode, we revisit three of our best episodes on preventing suicide. In episode 46, Lorenzo Norris, MD, host of the MDedge Psychcast, interviewed Igor Galynker, MD, about how to assess suicide crisis syndrome. Dr. Norris is editor in chief of MDedge Psychiatry, and assistant professor of psychiatry and behavioral sciences at George Washington University, Washington. Dr. Galynker is associate chairman for research in the department of psychiatry at Mount Sinai, New York. In episode 42, Dr. Norris interviewed Caroline Bonham, MD, and Avi Kreichman, MD, about addressing suicidality in rural communities a...2019-07-0233 minPsychcastPsychcastUpdate on the American Psychiatric Association – Part 2Headline: Update on the American Psychiatric Association – Part 2   Show Notes By Jacqueline Posada, MD, 4th-year resident in the department of psychiatry & behavioral sciences at George Washington University, Washington. Lorenzo Norris, MD, interview with Saul Levin, MD, MPA, CEO and medical director of the American Psychiatric Association (APA). Dr. Levin also is clinical professor at George Washington University.   Improving access to care and impact of psychiatrists is imperative.   Finding a doctor: More physicians need to be trained. Increasing the number of physicians can be accomplished throu...2019-06-2626 minPsychcastPsychcastEating disorders: Part IIFor more MDedge Podcasts go to mdedge.com/podcasts In part II of this Psychcast Masterclass, Patricia Westmoreland, MD, returns to discuss severe, enduring eating disorders, including management and ethical questions.  In Dr. RK this week, Renee Kohanksi explores the impact of censorship and self-censorship.  Email the show: podcasts@mdedge.com Interact with us on Twitter: @MDedgePsych Show Notes By Jacqueline Posada, MD, 4th-year resident in the department of psychiatry & behavioral sciences at George Washington University, Washington. Guest Patricia Westmoreland, MD, a forensic ps...2019-05-2222 minPsychcastPsychcastSpecial Episode: Introducing the Postcall PodcastIntroducing the Postcall Podcast.  Apple Podcasts: https://apple.co/2IeKD2y Google Podcasts: http://bit.ly/2OYLSZg At MDedge, we know that medicine can be a bit of an awakening at every step of your career. So, we launched the Postcall Podcast as a way to share your stories; what you love about medicine and what you love outside of your career. This is meant to be a place for you to find your truth. In the first episode, Nick Andrews welcomes the Editor-In-Chief of MDedge Psychiatry and the hos...2018-10-1254 min