Shows
NEJM InterviewsNEJM Outbreaks Updates — H5N1 in IndianaIn this NEJM Outbreaks Update, Editor-in-Chief Eric Rubin and Deputy Editor Lindsey Baden are joined by Indiana Commissioner of Public Health Lindsay Weaver to discuss the current state of avian influenza in Indiana. Eric Rubin is the Editor-in-Chief of the Journal. Lindsey Baden is a Deputy Editor of the Journal. Lindsay Weaver is the Indiana Commissioner of Public Health. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. E.J. Rubin and Others. NEJM Outbreaks Updates — H5N1 in Indiana. N Engl J Med. DOI: 10.1056/NEJMe2503583.2025-04-2220 min
NEJM InterviewsNEJM Outbreaks Update — H5N1: A View from the StatesIn this audio interview, Editor-in-Chief Eric Rubin and Deputy Editor Lindsey Baden are joined by state public health leaders Robbie Goldstein and Jennifer Shuford to discuss action against H5N1 in Massachusetts and Texas and across the nation. Eric Rubin is the Editor-in-Chief of the Journal. Lindsey Baden is a Deputy Editor of the Journal. Robert Goldstein is the Massachusetts Commissioner of Public Health. Jennifer Shuford is the Commissioner of the Texas Department of State Health Services. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. E.J. Rubin and Others. NEJM Outbreaks Update — H5N1: A Vi...2025-03-1134 min
NEJM InterviewsNEJM Outbreaks Update — H5N1In this NEJM Outbreaks Update, Editor-in-Chief Eric Rubin and Deputy Editor Lindsey Baden are joined by veterinarian and virologist Yoshihiro Kawaoka to discuss avian influenza and its current impact on chickens, cows, cats, and humans. Eric Rubin is the Editor-in-Chief of the Journal. Lindsey Baden is a Deputy Editor of the Journal. Yoshihiro Kawaoka is a veterinarian and virologist and a professor at the University of Wisconsin-Madison and the University of Tokyo. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. E.J. Rubin and Others. NEJM Outbreaks Update — H5N1. N Engl J Med. DOI: 10.1056/NEJMe2502267.2025-03-0419 min
NEJM AI Grand RoundsHealth Care at the Breaking Point: Dr. Zak Kohane Returns to NEJM AI Grand RoundsIn this return appearance on NEJM AI Grand Rounds, Dr. Zak Kohane joins hosts Raj Manrai and Andy Beam to discuss the evolving landscape of AI in medicine. As the first repeat guest on the show, Dr. Kohane shares insights on health care system challenges, the Human Values Project, and his perspectives on the most significant AI developments of 2024. The conversation explores everything from the practical applications of AI in health care to philosophical discussions about machine psychology and the future of doctor-patient relationships.
Transcript.
2025-01-151h 08
NEJM InterviewsNEJM at AHA — Phase 1 Study of AAV9.LAMP2B Gene Therapy in Danon DiseaseEric Rubin is the Editor-in-Chief of the Journal. Jane Leopold is a Deputy Editor of the Journal. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. E.J. Rubin, J. Leopold, and S. Morrissey. NEJM at AHA — Phase 1 Study of AAV9.LAMP2B Gene Therapy in Danon Disease. N Engl J Med. DOI: 10.1056/NEJMe2414477.2024-11-1704 minNEJM InterviewsNEJM at AHA — Routine Spironolactone in Acute Myocardial InfarctionEric Rubin is the Editor-in-Chief of the Journal. Jane Leopold is a Deputy Editor of the Journal. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. E.J. Rubin, J. Leopold, and S. Morrissey. NEJM at AHA — Routine Spironolactone in Acute Myocardial Infarction. N Engl J Med. DOI: 10.1056/NEJMe2414472.2024-11-1603 minNEJM InterviewsNEJM at AHA — Intensive Blood-Pressure Control in Patients with Type 2 DiabetesEric Rubin is the Editor-in-Chief of the Journal. Jane Leopold is a Deputy Editor of the Journal. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. E.J. Rubin, J. Leopold, and S. Morrissey. NEJM at AHA — Intensive Blood-Pressure Control in Patients with Type 2 Diabetes. N Engl J Med. DOI: 10.1056/NEJMe2414476.2024-11-1503 minNEJM InterviewsNEJM at AHA — Tirzepatide for Heart Failure with Preserved Ejection Fraction and ObesityEric Rubin is the Editor-in-Chief of the Journal. Jane Leopold is a Deputy Editor of the Journal. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. E.J. Rubin, J. Leopold, and S. Morrissey. NEJM at AHA — Tirzepatide for Heart Failure with Preserved Ejection Fraction and Obesity. N Engl J Med. DOI: 10.1056/NEJMe2414470.2024-11-1504 minNEJM InterviewsNEJM at AHA — CRISPR-Cas9 Gene Editing with Nexiguran Ziclumeran for ATTR CardiomyopathyEric Rubin is the Editor-in-Chief of the Journal. Jane Leopold is a Deputy Editor of the Journal. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. E.J. Rubin, J. Leopold, and S. Morrissey. NEJM at AHA — CRISPR-Cas9 Gene Editing with Nexiguran Ziclumeran for ATTR Cardiomyopathy. N Engl J Med. DOI: 10.1056/NEJMe2414473.2024-11-1503 minNEJM InterviewsNEJM at AHA — Catheter Ablation or Antiarrhythmic Drugs for Ventricular TachycardiaEric Rubin is the Editor-in-Chief of the Journal. Jane Leopold is a Deputy Editor of the Journal. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. E.J. Rubin, J. Leopold, and S. Morrissey. NEJM at AHA — Catheter Ablation or Antiarrhythmic Drugs for Ventricular Tachycardia. N Engl J Med. DOI: 10.1056/NEJMe2414471.2024-11-1502 minNEJM InterviewsNEJM at AHA — Left Atrial Appendage Closure after Ablation for Atrial FibrillationEric Rubin is the Editor-in-Chief of the Journal. Jane Leopold is a Deputy Editor of the Journal. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. E.J. Rubin, J. Leopold, and S. Morrissey. NEJM at AHA — Left Atrial Appendage Closure after Ablation for Atrial Fibrillation. N Engl J Med. DOI: 10.1056/NEJMe2414475.2024-11-1504 min
NEJM InterviewsNEJM at ESMO — Zolbetuximab in Gastric or Gastroesophageal Junction AdenocarcinomaDid you miss the ESMO Congress 2024? Listen here: NEJM Editor-in-Chief Eric Rubin and NEJM Evidence Associate Editor Oladapo Yeku discuss research that was presented at the 2024 European Society of Medical Oncology annual meeting. Visit NEJM.org to read the latest research.2024-09-1502 minNEJM InterviewsNEJM at ESMO — Phase 3 Trial of Cabozantinib in Advanced Neuroendocrine TumorsDid you miss the ESMO Congress 2024? Listen here: NEJM Editor-in-Chief Eric Rubin and NEJM Evidence Associate Editor Oladapo Yeku discuss research that was presented at the 2024 European Society of Medical Oncology annual meeting. Visit NEJM.org to read the latest research.2024-09-1502 minNEJM InterviewsNEJM at ESMO — Perioperative Durvalumab with Neoadjuvant Chemotherapy in Operable Bladder CancerDid you miss the ESMO Congress 2024? Listen here: NEJM Editor-in-Chief Eric Rubin and NEJM Evidence Associate Editor Oladapo Yeku discuss research that was presented at the 2024 European Society of Medical Oncology annual meeting. Visit NEJM.org to read the latest research.2024-09-1403 minNEJM InterviewsNEJM at ESMO — Overall Survival with Pembrolizumab in Early-Stage Triple- Negative Breast CancerDid you miss the ESMO Congress 2024? Listen here: NEJM Editor-in-Chief Eric Rubin and NEJM Evidence Associate Editor Oladapo Yeku discuss research that was presented at the 2024 European Society of Medical Oncology annual meeting. Visit NEJM.org to read the latest research.2024-09-1403 minNEJM InterviewsNEJM at ESMO — Final, 10-Year Outcomes with Nivolumab plus Ipilimumab in Advanced MelanomaDid you miss the ESMO Congress 2024? Listen here: NEJM Editor-in-Chief Eric Rubin and NEJM Evidence Associate Editor Oladapo Yeku discuss research that was presented at the 2024 European Society of Medical Oncology annual meeting. Visit NEJM.org to read the latest research.2024-09-1403 minNEJM InterviewsNEJM at ESMO — Adjuvant Pembrolizumab versus Observation in Muscle-Invasive Urothelial CarcinomaDid you miss the ESMO Congress 2024? Listen here: NEJM Editor-in-Chief Eric Rubin and NEJM Evidence Associate Editor Oladapo Yeku discuss research that was presented at the 2024 European Society of Medical Oncology annual meeting. Visit NEJM.org to read the latest research.2024-09-1403 minNEJM InterviewsNEJM at ESMO — Trastuzumab Deruxtecan after Endocrine Therapy in Metastatic Breast CancerDid you miss the ESMO Congress 2024? Listen here: NEJM Editor-in-Chief Eric Rubin and NEJM Evidence Associate Editor Oladapo Yeku discuss research that was presented at the 2024 European Society of Medical Oncology annual meeting. Visit NEJM.org to read the latest research.2024-09-1403 minNEJM InterviewsNEJM at ESMO — Pembrolizumab in HER2+ Gastric CancerDid you miss the ESMO Congress 2024? Listen here: NEJM Editor-in-Chief Eric Rubin and NEJM Evidence Associate Editor Oladapo Yeku discuss research that was presented at the 2024 European Society of Medical Oncology annual meeting. Visit NEJM.org to read the latest research.2024-09-1302 minNEJM InterviewsNEJM at ESMO — Ponsegromab in Cancer CachexiaDid you miss the ESMO Congress 2024? Listen here: NEJM Editor-in-Chief Eric Rubin and NEJM Evidence Associate Editor Oladapo Yeku discuss research that was presented at the 2024 European Society of Medical Oncology annual meeting. Visit NEJM.org to read the latest research.2024-09-1302 minNEJM InterviewsNEJM at ESMO — Preoperative Chemoradiotherapy for Resectable Gastric CancerDid you miss the ESMO Congress 2024? Listen here: NEJM Editor-in-Chief Eric Rubin and NEJM Evidence Associate Editor Oladapo Yeku discuss research that was presented at the 2024 European Society of Medical Oncology annual meeting. Visit NEJM.org to read the latest research.2024-09-1302 minNEJM InterviewsNEJM at ESC — Plozasiran for Managing Persistent Chylomicronemia and Pancreatitis RiskDid you miss the ESC Congress 2024? In a series of audio interviews (featured below), Editor-in-Chief Eric Rubin and Deputy Editor Jane Leopold discuss research that was presented at the 2024 European Society of Cardiology annual meeting. Visit NEJM.org to read the latest research.2024-09-0102 minNEJM InterviewsNEJM at ESC — Invasive versus Conservative Strategy for Older Patients with Myocardial InfarctionDid you miss the ESC Congress 2024? In this podcast, Editor-in-Chief Eric Rubin and Deputy Editor Jane Leopold discuss research that was presented at the 2024 European Society of Cardiology annual meeting. Visit NEJM.org to read the latest research.2024-08-3103 minNEJM InterviewsNEJM at ESC — Edoxaban Antithrombotic Therapy for Atrial Fibrillation and Stable Coronary Artery DiseaseDid you miss the ESC Congress 2024? In this podcast, Editor-in-Chief Eric Rubin and Deputy Editor Jane Leopold discuss research that was presented at the 2024 European Society of Cardiology annual meeting. Visit NEJM.org to read the latest research.2024-08-3104 minNEJM InterviewsNEJM at ESC — Asundexian versus Apixaban in Patients with Atrial FibrillationDid you miss the ESC Congress 2024? In this podcast, Editor-in-Chief Eric Rubin and Deputy Editor Jane Leopold discuss research that was presented at the 2024 European Society of Cardiology annual meeting. Visit NEJM.org to read the latest research.2024-08-3103 minNEJM InterviewsNEJM at ESC — Finerenone in Heart Failure for Mildly Reduced or Preserved Ejection FractionDid you miss the ESC Congress 2024? In this podcast, Editor-in-Chief Eric Rubin and Deputy Editor Jane Leopold discuss research that was presented at the 2024 European Society of Cardiology annual meeting. Have a listen! Visit NEJM.org to read the latest research.2024-08-3103 minNEJM InterviewsNEJM at ESC — Inflammation, Cholesterol, Lipoprotein(a) and 30-Year Cardiovascular Outcomes in WomenDid you miss the ESC Congress 2024? In this podcast, Editor-in-Chief Eric Rubin and Deputy Editor Jane Leopold discuss research that was presented at the 2024 European Society of Cardiology annual meeting. Visit NEJM.org to read the latest research.2024-08-3003 minNEJM InterviewsNEJM at ESC — Transcatheter Repair versus Surgery for Secondary Mitral RegurgitationDid you miss the ESC Congress 2024? In this podcast, Editor-in-Chief Eric Rubin and Deputy Editor Jane Leopold discuss research that was presented at the 2024 European Society of Cardiology annual meeting. Visit NEJM.org to read the latest research.2024-08-3003 minNEJM InterviewsNEJM at ESC — Transcatheter Valve Repair in Heart Failure with Moderate to Severe Mitral RegurgitationDid you miss the ESC Congress 2024? In this podcast, Editor-in-Chief Eric Rubin and Deputy Editor Jane Leopold discuss research that was presented at the 2024 European Society of Cardiology annual meeting. Visit NEJM.org to read the latest research.2024-08-3003 minNEJM InterviewsNEJM at ESC — PCI in Patients Undergoing Transcatheter Aortic-Valve ImplantationDid you miss the ESC Congress 2024? In this podcast, Editor-in-Chief Eric Rubin and Deputy Editor Jane Leopold discuss research that was presented at the 2024 European Society of Cardiology annual meeting. Visit NEJM.org to read the latest research.2024-08-3004 minNEJM InterviewsNEJM at ESC — Continuation versus Interruption of Oral Anticoagulation during TAVDid you miss the ESC Congress 2024? In this podcast, Editor-in-Chief Eric Rubin and Deputy Editor Jane Leopold discuss research that was presented at the 2024 European Society of Cardiology annual meeting. Visit NEJM.org to read the latest research.2024-08-3004 minNEJM InterviewsNEJM at ESC — Beta Blocker Interruption or Continuation with Prior Myocardial InfarctionDid you miss the ESC Congress 2024? In this podcast, Editor-in-Chief Eric Rubin and Deputy Editor Jane Leopold discuss research that was presented at the 2024 European Society of Cardiology annual meeting. Visit NEJM.org to read the latest research.2024-08-2903 minNEJM InterviewsNEJM at ESC — Vutrisiran in Patients with Transthyretin Amyloidosis with CardiomyopathyDid you miss the ESC Congress 2024? In this podcast, Editor-in-Chief Eric Rubin and Deputy Editor Jane Leopold discuss research that was presented at the 2024 European Society of Cardiology annual meeting. Visit NEJM.org to read the latest research.2024-08-2903 min
Intention to TreatCovid Vaccines — Playing the Long GameIn this first episode of “Intention to Treat,” NEJM editor-in-chief Eric Rubin and his colleague at the FDA Vaccine Advisory Committee, Paul Offit, consider the achievements, limitations, and expectations of Covid vaccines.
A transcript of this episode is available at nejm.org/doi/full/10.1056/NEJMp2300222.
2023-01-2535 min
NEJM InterviewsNEJM AI Grand RoundsNEJM AI Grand Rounds, hosted by Arjun (Raj) Manrai, Ph.D. and Andrew Beam, Ph.D., features informal conversations with a variety of unique experts exploring the deep issues at the intersection of artificial intelligence, machine learning, and medicine. You’ll learn how AI will change clinical practice and healthcare, how it will impact the patient experience, and about the people who are pushing for innovation. Whether you are an AI researcher or a practicing clinician, these conversations will enlighten and surprise you as we journey through this very exciting field. Produced by NEJM Group.2022-12-2101 minNEJM AI Grand RoundsTrailer: Introducing NEJM AI Grand Rounds Podcast
[Transcript]
How will AI change clinical practice and healthcare, and how will it impact the patient experience? Who are the people pushing for change and what are their goals? These are just a few of the topics that we hope to explore on NEJM AI Grand Rounds, a new podcast from NEJM Group. This podcast will be an informal conversation with a variety of unique experts exploring the deep issues at the intersection of artificial intelligence and medicine. Whether you are an AI researcher or a practicing clinician, we hope these conversations will enlighten and...2022-12-0501 min
Clinical ConversationsPodcast 298: COPD exacerbations — 7 days of antibiotics versus 2A VIDEO RECORDING OF THIS INTERVIEW IS AVAILABLE AT THIS LINK.
In treating most exacerbations of chronic obstructive pulmonary disease (COPD) the usual regimen consists of prednisone plus 5- to 7-days of antibiotics. But what if a shorter course of antibiotic therapy would do? That would be both convenient for patients and less likely to promote antibiotic resistance.
A recent paper in Therapeutic Advances in Respiratory Disease describes just such a strategy: patients received prednisone plus either 2 or 7 days of levofloxacin. There was no substantive difference in clinical results between the groups. Summarized in NEJM Jo...2022-09-0214 minClinical ConversationsPodcast 301: Monkeypox — what to look for, how to treatA VIDEO RECORDING OF THIS INTERVIEW IS AVAILABLE HERE.
This time, we look to New York for guidance on recognizing and treating monkeypox.
Dr. Eric Meyerowitz of Montefiore and Dr. Stephen Baum of Einstein will lead you through the monkeypox thicket in a 17-minute chat.
Included below is information for patients as well as links to some key articles of interest to clinicians.
LINKS:
For patients: Dr. Barry Zingman’s “Monkeypox — What you need to know”
For clinicians:
NEJM article on monkeypox in 16 countries
NEJM Case Records of the...2022-08-1917 minClinical ConversationsPodcast 299: Lung cancer and atezolizumab — results from the IMpower010 trialA VIDEO RECORDING OF THIS INTERVIEW IS AVAILABLE HERE.
Interim results on overall survival in phase 3 of the IMpower010 trial were presented at this year’s meeting of the International Assosciation for the Study of Lung Cancer (IASLC). As part of the NEJM Group’s coverage of the conference, Christine Sadlowski interviewed the presenter, Dr. Enriqueta Felip. In a 15-minute interview, she discusses the implications for different patient groups and the past, present, and future of the IMpower trial, which tests adjuvant atezolizumab following platinum-based chemotherapy in patients with resected early-stage non–small-cell lung cancer.
INTERVIEW...2022-08-1014 minClinical ConversationsPodcast 295: How should clinicians manage severe (but asymptomatic) carotid artery stenosis while awaiting CREST-2’s results?CREST-2’s results are probably more than a year away. In the meantime, what to do about diagnosed severe (but asymptomatic) carotid stenosis? Recent results suggest that medical management compares favorably with the surgical approach.
In this edition, we address the question with a conversation between Dr. Allan Brett, NEJM Journal Watch‘s editor-in-chief, and Dr. Seemant Chaturvedi, a University of Maryland neurologist who serves on CREST-2’s executive committee.
[Running time: 16 minutes]
NEJM Journal Watch coverage of a recent JAMA paper on the topic.
The post Podcast 295: How should clinicians...2022-07-0615 min
NEJM InterviewsNEJM Interview: Dr. Michele Evans on the role that public policies have played in exacerbating health inequities in the United States.Dr. Michele Evans is a senior investigator and the deputy scientific director at the National Institute on Aging and a member of the Journal's Editorial Board. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. M.K. Evans. Health Equity — Are We Finally on the Edge of a New Frontier? N Engl J Med 2020;383:997-999.2020-09-0914 min
Curbside ConsultsNEJM Resident 360 QI Challenge Winning Submission with Dr. Elissa FalconerIn this special episode of Curbside Consults, we interview Dr. Elissa Falconer, the team leader of the NEJM Resident 360 QI Challenge winning submission. Dr. Falconer is a general surgery resident at Atlanta VA Healthcare System. The title of their quality improvement...2020-09-0915 minNEJM InterviewsNEJM Interview: Dr. Richard Schilsky on milestones in the prevention and treatment of cancer in the United States.Dr. Richard Schilsky is the chief medical officer and executive vice president of the American Society of Clinical Oncology and a member of the Journal’s Editorial Board. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. R.L. Schilsky and Others. Progress in Cancer Research, Prevention, and Care. N Engl J Med 2020;383:897-900.2020-09-0216 minClinical ConversationsPodcast 273: The journals and the pandemic — NEJMEric Rubin is editor-in-chief of the New England Journal of Medicine. I asked him how COVID-19 has affected that journal, which has been around since the War of 1812 and seen its share of pandemics. Listen in — it’s the first in a planned series of interviews with the editors of the principal clinical journals. Running time: 19 minutes […]
The post Podcast 273: The journals and the pandemic — NEJM first appeared on Clinical Conversations.2020-08-2918 minNEJM InterviewsNEJM Interview: Dr. Elizabeth McGlynn on why efforts to improve health care quality have often been unsuccessful and where we can go from hereDr. Elizabeth McGlynn is vice president at Kaiser Permanente Research and executive director of the Kaiser Permanente Center for Effectiveness and Safety Research. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. E.A. McGlynn. Improving the Quality of U.S. Health Care — What Will It Take? N Engl J Med 2020;383:801-803.2020-08-2612 minNEJM InterviewsNEJM Interview: Dr. Justin Berk on starting patients recently released from incarceration on treatment for opioid use disorder.Dr. Justin Berk is an assistant professor in the Departments of Medicine and Pediatrics at Warren Alpert Medical School of Brown University. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. J. Berk. A Good Place to Start — Low-Threshold Buprenorphine Initiation. N Engl J Med 2020;383:701-703. H.L.F. Cooper and Others. When Prescribing Isn’t Enough — Pharmacy-Level Barriers to Buprenorphine Access. N Engl J Med 2020;383:703-705.2020-08-1910 minNEJM InterviewsNEJM Interview: Dr. Katherine Baicker on assessments of health care spending in the United States and moving toward higher-value use of resources.Dr. Katherine Baicker is dean of the University of Chicago Harris School of Public Policy. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. K. Baicker and A. Chandra. Do We Spend Too Much on Health Care? N Engl J Med 2020;383:605-608.2020-08-1210 minClinical ConversationsPodcast 272: And now for something completely different… almostDr. Paul Sax writes the closest thing that the NEJM Group has to humor. He’s serious, of course, since his blog “HIV and ID Observations” concerns all things infectious . But he sprinkles in the odd cartoon or links to … dog videos, fer cryin’ out loud. He scours the ID literature (and we must include […]
The post Podcast 272: And now for something completely different… almost first appeared on Clinical Conversations.2020-08-0809 minNEJM InterviewsNEJM Interview: Dr. Donald Berwick on the history and challenges of measuring and improving health care quality in the United States.Dr. Donald Berwick is president emeritus and a senior fellow at the Institute for Healthcare Improvement. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. D.M. Berwick and C.K. Cassel. The NAM and the Quality of Health Care — Inflecting a Field. N Engl J Med 2020;383:505-508.2020-08-0510 minNEJM InterviewsNEJM Interview: Dr. Caroline Buckee on the uses — and limitations — of epidemiologic modeling to predict the spread of Covid-19.Dr. Caroline Buckee is the associate director of the Center for Communicable Disease Dynamics at the Harvard T.H. Chan School of Public Health. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. I. Holmdahl and C. Buckee. Wrong but Useful — What Covid-19 Epidemiologic Models Can and Cannot Tell Us. N Engl J Med 2020;383:303-305. E.C. Schneider. Failing the Test — The Tragic Data Gap Undermining the U.S. Pandemic Response. N Engl J Med 2020;383:299-302.2020-07-2210 minNEJM InterviewsNEJM Interview: Dr. Michelle Morse on how academic medical centers can engage with social movements to confront inequities in health care practices.Dr. Michelle Morse is an assistant professor at Harvard Medical School and cofounder of EqualHealth. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. M. Morse and J. Loscalzo. Creating Real Change at Academic Medical Centers — How Social Movements Can Be Timely Catalysts. N Engl J Med 2020;383:199-201.2020-07-1516 minNEJM InterviewsNEJM Interview: Dr. Martin Roland on opportunities for using socially oriented interventions when illnesses are influenced by social circumstances.Dr. Martin Roland is an emeritus professor of health services research at the University of Cambridge and a fellow at Murray Edwards College. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. M. Roland, S. Everington, and M. Marshall. Social Prescribing — Transforming the Relationship between Physicians and Their Patients. N Engl J Med 2020;383:97-99.2020-07-0810 minNEJM InterviewsNEJM Interview: Dr. Anthony Fauci on progress made during the past four decades of the HIV/AIDS pandemic and ongoing efforts to end this threat.Dr. Anthony Fauci is the director of the National Institute of Allergy and Infectious Diseases. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. A.S. Fauci and H.C. Lane. Four Decades of HIV/AIDS — Much Accomplished, Much to Do. N Engl J Med 2020;383:1-4.2020-07-0118 minCurbside ConsultsStatistical Review − Secondary Outcomes with Dr. David HarringtonIn this episode of Curbside Consults: Statistical Review, we explore the interpretation of secondary outcomes in clinical trials using the following two articles recently published in NEJM: Bonaca MP et al. Rivaroxaban in Peripheral Artery Disease after Revascularization...2020-06-2521 minNEJM InterviewsNEJM Interview: Dr. Eric Rubin and Dr. Lindsey Baden on the challenges of safe reopeningEric Rubin is the Editor-in-Chief of the Journal. Lindsey Baden is a Deputy Editor of the Journal. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. E.J. Rubin, L.R. Baden, and S. Morrissey. Audio Interview: The Challenges of Safe Reopening. N Engl J Med 2020;382:e113.2020-06-2417 minNEJM InterviewsNEJM Interview: Dr. Pamela Hartzband on lessons from organizational psychology for ameliorating physician burnout.Dr. Pamela Hartzband is an endocrinologist at Beth Israel Deaconess Medical Center and an assistant professor at Harvard Medical School. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. P. Hartzband and J. Groopman. Physician Burnout, Interrupted. N Engl J Med 2020;382:2485-2487.2020-06-2411 minNEJM InterviewsNEJM Interview: Dr. Eric Rubin and Dr. Lindsey Baden on a look at SARS-CoV-2 transmissionEric Rubin is the Editor-in-Chief of the Journal. Lindsey Baden is a Deputy Editor of the Journal. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. E.J. Rubin, L.R. Baden, and S. Morrissey. Audio Interview: A Look at SARS-CoV-2 Transmission. N Engl J Med 2020;382:e112.2020-06-1720 minNEJM InterviewsNEJM Interview: Dr. Debra Weinstein on the announcement that scores for Step 1 of the U.S. Medical Licensing Examination will be reported as pass or fail.Dr. Debra Weinstein is vice president for graduate medical education at Mass General Brigham and a member of the Journal’s Perspective Advisory Board. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. C.G. Prober. Grading Changes for USMLE Step 1 — A Golden Opportunity to Recalibrate Medical Education Priorities. N Engl J Med 2020;382:2385-2387. L.L. Willett. The Impact of a Pass/Fail Step 1 — A Residency Program Director’s View. N Engl J Med 2020;382:2387-2389.2020-06-1711 minNEJM InterviewsNEJM Interview: Dr. Benjamin Sommers on increased pressure on state Medicaid programs caused by Covid-19 and policies for strengthening Medicaid.Dr. Benjamin Sommers is a primary care internist and a professor of health policy and economics at the Harvard T.H. Chan School of Public Health. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. J. Gruber and B.D. Sommers. Paying for Medicaid — State Budgets and the Case for Expansion in the Time of Coronavirus. N Engl J Med 2020;382:2280-2282.2020-06-1010 minNEJM InterviewsNEJM Interview: Dr. Eric Rubin, Dr. Lindsey Baden, and Dr. Michele Evans on the impact of Covid-19 on minority communitiesEric Rubin is the Editor-in-Chief of the Journal. Lindsey Baden is a Deputy Editor of the Journal. Michele Evans is a Senior Investigator and Deputy Scientific Director at the National Institute on Aging and a member of the Journal’s editorial board. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. E.J. Rubin and Others. Audio Interview: The Impact of Covid-19 on Minority Communities. N Engl J Med 2020;382:e111.2020-06-1019 minNEJM InterviewsNEJM Interview: Dr. Erin Fraher on opportunities for expanding health workforce capacity during the Covid-19 pandemic.Dr. Erin Fraher is the director of the Carolina Health Workforce Research Center at the University of North Carolina at Chapel Hill. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. E.P. Fraher and Others. Ensuring and Sustaining a Pandemic Workforce. N Engl J Med 2020;382:2181-2183.2020-06-0313 minNEJM InterviewsNEJM Interview: Dr. Eric Rubin and Dr. Lindsey Baden on diagnosis and early treatment of Covid-19Eric Rubin is the Editor-in-Chief of the Journal. Lindsey Baden is a Deputy Editor of the Journal. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. E.J. Rubin, L.R. Baden, and S. Morrissey. Audio Interview: Diagnosis and Early Treatment of Covid-19. N Engl J Med 2020;382:e103.2020-06-0321 minNEJM InterviewsNEJM Interview: Dr. Lisa Rosenbaum on how health care workers have responded to the challenges of caring for patients during the Covid-19 pandemic.Dr. Lisa Rosenbaum is a national correspondent for the Journal. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. L. Rosenbaum. Harnessing Our Humanity — How Washington’s Health Care Workers Have Risen to the Pandemic Challenge. N Engl J Med 2020;382:2069-2071.2020-05-2715 minNEJM InterviewsNEJM Interview: Dr. Eric Rubin and Dr. Lindsey Baden on new data on remdesivir in Covid-19Eric Rubin is the Editor-in-Chief of the Journal. Lindsey Baden is a Deputy Editor of the Journal. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. E.J. Rubin, L.R. Baden, and S. Morrissey. Audio Interview: New Data on Remdesivir in Covid-19. N Engl J Med 2020;382:e94.2020-05-2721 minNEJM InterviewsNEJM Interview: Dr. Nicole Lurie on rapid vaccine development, including new tools to facilitate vaccine testing and manufacturing and persistent challenges.Dr. Nicole Lurie is a strategic advisor to the CEO of the Coalition for Epidemic Preparedness Innovations. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. N. Lurie and Others. Developing Covid-19 Vaccines at Pandemic Speed. N Engl J Med 2020;382:1969-1973.2020-05-2013 minNEJM InterviewsNEJM Interview: Dr. Eric Rubin and Dr. Lindsey Baden on capitalizing on immune responses to Covid-19Eric Rubin is the Editor-in-Chief of the Journal. Lindsey Baden is a Deputy Editor of the Journal. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. E.J. Rubin, L.R. Baden, and S. Morrissey. Audio Interview: Capitalizing on Immune Responses to Covid-19. N Engl J Med 2020;382:e93.2020-05-2020 minNEJM InterviewsNEJM Interview: Dr. Marco Vergano on caring for critically ill patients with Covid-19 and resource allocation in the ICU.Dr. Marco Vergano is an anesthesiologist and chair of the Ethics Section of the Italian College of Anesthesia, Analgesia, Resuscitation, and Intensive Care. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. L. Rosenbaum. Facing Covid-19 in Italy — Ethics, Logistics, and Therapeutics on the Epidemic’s Front Line. N Engl J Med 2020;382:1873-1875.2020-05-1307 minNEJM InterviewsNEJM Interview: Dr. Eric Rubin and Dr. Lindsey Baden on finding reliable information about Covid-19Eric Rubin is the Editor-in-Chief of the Journal. Lindsey Baden is a Deputy Editor of the Journal. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. E.J. Rubin, L.R. Baden, and S. Morrissey. Audio Interview: Finding Reliable Information about Covid-19. N Engl J Med 2020;382:e81.2020-05-1319 minNEJM InterviewsNEJM Interview: Prof. Rachel Sachs on the Trump administration’s proposal to allow states to develop programs to import prescription drugs from Canada.Prof. Rachel Sachs is an associate professor of law at Washington University in Saint Louis. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. R.E. Sachs and N. Bagley. Importing Prescription Drugs from Canada — Legal and Practical Problems with the Trump Administration’s Proposal. N Engl J Med 2020;382:1777-1779.2020-05-0610 minNEJM InterviewsNEJM Interview: Dr. Eric Rubin and Dr. Lindsey Baden on studying potential Covid-19 therapiesEric Rubin is the Editor-in-Chief of the Journal. Lindsey Baden is a Deputy Editor of the Journal. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. E.J. Rubin, L.R. Baden, and S. Morrissey. Audio Interview: Studying Potential Covid-19 Therapies. N Engl J Med 2020;382:e72.2020-05-0622 minNEJM InterviewsNEJM Interview: Dr. Judd Hollander on how health systems can use telemedicine services during the Covid-19 pandemic.Dr. Judd Hollander is the associate dean for strategic health initiatives at Sidney Kimmel Medical College of Thomas Jefferson University. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. J.E. Hollander and B.G. Carr. Virtually Perfect? Telemedicine for Covid-19. N Engl J Med 2020;382:1679-1681.2020-04-2915 minNEJM InterviewsNEJM Interview: Dr. Eric Rubin and Dr. Lindsey Baden on Loosening Covid-19 RestrictionsEric Rubin is the Editor-in-Chief of the Journal. Lindsey Baden is a Deputy Editor of the Journal. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. E.J. Rubin, L.R. Baden, and S. Morrissey. Audio Interview: Loosening Covid-19 Restrictions. N Engl J Med 2020;382:e67.2020-04-2922 minNEJM InterviewsNEJM Interview: Dr. William Shrank on the management of clinical and social risk factors in quality-assessment and payment programs.Dr. William Shrank is the chief medical officer at Humana. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. S.K. Agrawal and W.H. Shrank. Clinical and Social Risk Adjustment — Reconsidering Distinctions. N Engl J Med 2020;382:1581-1583.2020-04-2210 minNEJM InterviewsNEJM Interview: Dr. Eric Rubin and Dr. Lindsey Baden on approaches to Covid-19 vaccines and antivirals.Eric Rubin is the Editor-in-Chief of the Journal. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. E.J. Rubin, L.R. Baden, and S. Morrissey. Audio Interview: Approaches to Covid-19 Vaccines and Antivirals. N Engl J Med 2020;382:e58.2020-04-2221 minNEJM InterviewsNEJM Interview: Dr. Amy Finkelstein on the use of evidence from randomized, controlled trials to answer questions about health care policy.Dr. Amy Finkelstein is a professor of economics at the Massachusetts Institute of Technology. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. A. Finkelstein. A Strategy for Improving U.S. Health Care Delivery — Conducting More Randomized, Controlled Trials. N Engl J Med 2020;382:1485-1488.2020-04-1510 minNEJM InterviewsNEJM Interview: Dr. Eric Rubin and Dr. Lindsey Baden on caring for patients with Covid-19.Eric Rubin is the Editor-in-Chief of the Journal. Lindsey Baden is a Deputy Editor of the Journal. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. E.J. Rubin, L.R. Baden, and S. Morrissey. Audio Interview: Caring for Patients with Covid-19. N Engl J Med 2020;382:e50.2020-04-1518 minNEJM InterviewsNEJM Interview: Prof. Michelle Mello on health professionals’ moral duty to intervene in response to sexual harassment and gender bias.Prof. Michelle Mello is a professor of law and of health research and policy at Stanford University. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. M.M. Mello and R. Jagsi. Standing Up against Gender Bias and Harassment — A Matter of Professional Ethics. N Engl J Med 2020;382:1385-1387.2020-04-0810 minNEJM InterviewsNEJM Interview: Dr. Eric Rubin and Dr. Lindsey Baden on emerging tools in the fight against Covid-19.Eric Rubin is the Editor-in-Chief of the Journal. Lindsey Baden is a Deputy Editor of the Journal. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. E.J. Rubin, L.R. Baden, and S. Morrissey. Audio Interview: Emerging Tools in the Fight against Covid-19. N Engl J Med 2020;382:e39.2020-04-0820 minCurbside ConsultsStatistical Review - Studying Outbreaks with COVID-19In this statistical review episode of Curbside Consults, we explore descriptive epidemiology studies of the COVID-19 outbreak using an article by Guan and colleagues published online in NEJM on February 28, 2020. To help explain the approach to outbreak study analysis...2020-04-0119 minNEJM InterviewsNEJM Interview: Dr. Eric Rubin and Dr. Lindsey Baden on lessons from Covid-19 hotspots.Eric Rubin is the Editor-in-Chief of the Journal. Lindsey Baden is a Deputy Editor of the Journal. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. E.J. Rubin, L.R. Baden, and S. Morrissey. Audio Interview: Lessons from Covid-19 Hotspots. N Engl J Med 2020;382:e35.2020-04-0116 minNEJM InterviewsNEJM Interview: Dr. Nora Volkow on stigma against people who use drugs and its effects on care delivery and the burden of substance use disorders.Dr. Nora Volkow is the director of the National Institute on Drug Abuse. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. N.D. Volkow. Stigma and the Toll of Addiction. N Engl J Med 2020;382:1289-1290.2020-04-0111 minNEJM InterviewsNEJM Interview: Prof. Erin Fuse Brown on Congress’s failure to address surprise medical bills in 2019 and renewed efforts in 2020.Prof. Erin Fuse Brown is an associate professor of law at Georgia State University. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. E.C. Fuse Brown. Stalled Federal Efforts to End Surprise Billing — The Role of Private Equity. N Engl J Med 2020;382:1189-1191.2020-03-2513 minNEJM InterviewsNEJM Interview: Dr. Eric Rubin and Dr. Lindsey Baden on practical measures to help prevent Covid-19.Eric Rubin is the Editor-in-Chief of the Journal. Lindsey Baden is a Deputy Editor of the Journal. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. E.J. Rubin, L.R. Baden, and S. Morrissey. Audio Interview: Practical Measures to Help Prevent Covid-19. N Engl J Med 2020;382:e32.2020-03-2514 minNEJM InterviewsNEJM Interview: Dr. Eric Rubin and Dr. Lindsey Baden on new research on possible treatments for Covid-19.Eric Rubin is the Editor-in-Chief of the Journal. Lindsey Baden is a Deputy Editor of the Journal. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. E.J. Rubin, L.R. Baden, and S. Morrissey. Audio Interview: New Research on Possible Treatments for Covid-19. N Engl J Med 2020;382:e30.2020-03-1815 minNEJM InterviewsNEJM Interview: Dr. William Haseltine on lessons from Egypt’s screening for hepatitis C in the context of its universal disease screening and treatment program.Dr. William Haseltine is the chairman and president of ACCESS Health International. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. W.A. Haseltine. Universal Disease Screening and Treatment — The Egyptian Example. N Engl J Med 2020;382:1081-1083.2020-03-1808 minCurbside ConsultsNEJM Resident 360 QI Challenge with the NEJM Editorial Fellows 2019-20In this special episode of Curbside Consults, this year’s NEJM Editorial Fellows discuss Quality Improvement (QI) in residency and the launch of the NEJM Resident 360 QI Challenge.2020-02-2109 minCurbside ConsultsNEJM Editorial Fellowship 2018/2019 Wrap-UpTogether with Dr. David Harrington, 2018/2019 NEJM Editorial Fellows Angie, Angela, and Amanda summarize and wrap up the NEJM experience. 2019-10-1617 minCurbside ConsultsStatistical Review – Missing Data with Dr. David HarringtonMissing data are common in randomized, controlled trials. Why does this happen? How do we interpret these missing data? In this episode of Curbside Consults, Dr. David Harrington, statistical editor at the NEJM, joins us for a discussion on missing data and how to interpret missing data in studies.2019-09-2017 minCurbside ConsultsOsteoporosis with Dr. Clifford J. RosenOsteoporosis affects more than 10 million people living in the United States. Although a number of medications are available for treatment of osteoporosis, it remains undertreated. In this episode of Curbside Consults, Dr. Clifford J. Rosen, Professor of Medicine at Tufts University School of Medicine and Associate Editor at the NEJM, joins us to...2019-09-0434 minCurbside ConsultsStatistical Review – Early Trial Cessation – When, Why and How to Interpret with Dr. David HarringtonClinical trials can be stopped early for a range of reasons. But when that happens, it can be tricky to interpret the results and to understand the reasons why the trial was stopped in the first place. Join us in this episode of Curbside Consults with Dr. David Harrington, statistical editor at the NEJM, as we discuss...2019-07-2410 minCurbside ConsultsTime Limits for Thrombolysis in Acute Ischemic Stroke with Dr. Steven FeskeIntravenous thrombolysis has been an essential component in the management of acute ischemic stroke. Current guidelines recommend that thrombolysis be administered within 3 hours of the onset of first neurologic symptoms. However, two recent trials published in NEJM challenge this time paradigm. In this episode of Curbside Consults...2019-07-1128 minCurbside ConsultsStatistical Review – Pragmatic Trials with Dr. David HarringtonPractical or pragmatic trials are designed to show the effectiveness of an intervention in the complex clinical setting of daily practice. But what makes a trial pragmatic? Can a clinical trial ever be completely pragmatic? Join us in this episode of Curbside Consults with Dr. David Harrington, statistical editor at the NEJM, as we discuss the elements...2019-06-2611 minCurbside ConsultsStatistical Review – Composite Outcomes with Dr. David HarringtonComposite outcomes are frequently used as primary outcomes in randomized-controlled trials and observational studies. Why are they used? What are the limitations of their use? How are composite outcomes interpreted? Join us in this episode as Dr. David Harrington, statistical editor at the NEJM, helps breakdown composite outcomes.2019-05-3010 minCurbside ConsultsStatistical Review – Non-Inferiority Trials with Dr. David HarringtonEver read a paper and feel a bit confused about all the statistical jargon and how to properly interpret the findings? At NEJM Resident 360, we’re bringing you Statistical Review which aims to cover some key areas in research methodology and trial design. On this episode, Dr David Harrington, our statistical editor here at the NEJM...2019-05-0114 minCurbside ConsultsStatistical Review – Power with Dr. David HarringtonEver read a paper and feel a bit confused about all the statistical jargon and how to properly interpret the findings? At NEJM Resident 360, we’re trying something new and bringing you Statistical Review which aims to cover some key areas in research methodology and trial design. On this episode, Dr. David Harrington our statistical editor here...2019-03-2915 minCurbside ConsultsStatistical Review – Intention-to-Treat Versus Per-Protocol AnalysesEver read a paper and feel a bit confused about all the statistical jargon and how to properly interpret the findings? At NEJM Resident 360, we’re trying something new and bringing you Statistical Review which aims to cover some key areas in research methodology and trial design. On this episode, we discuss intention-to-treat and per-protocol...2019-02-0412 minCurbside ConsultsWorsening Asthma Symptoms and Preventing Asthma Exacerbations with Dr. Jeff DrazenWinter is upon us and asthma exacerbations are on the rise. But how well can clinicians and patients predict and prevent these asthma exacerbations before they start? NEJM Editor-in-Chief and Pulmonologist Dr. Jeff Drazen discusses the challenge clinicians and patients face in the setting of worsening asthma symptoms, also known as...2019-01-0425 minCurbside ConsultsStatistical Review – P-values, Outcomes, Point-estimates and Confidence IntervalsEver read a paper and feel a bit confused about all the statistical jargon and how to properly interpret the findings? At NEJM Resident 360, we’re trying something new and bringing you Statistical Review which aims to cover some key areas in research methodology and trial design. On this episode, we aim to cover basic ground over study...2018-12-0512 minCurbside ConsultsAcute MI and Cardiogenic Shock with Dr. John JarchoEvery medical resident will need to manage acute myocardial infarction at some stage. But what makes a patient with acute MI and cardiogenic shock more of a challenge to manage? NEJM Deputy Editor and Cardiologist Dr John Jarcho discusses the details around the pathophysiology and management in these patients and the recent paper...2018-11-1328 minCurbside ConsultsIV Fluids and Glucocorticoids for Sepsis with Dr. Kathryn HibbertIn this interview, Dr. Kathryn Hibbert reviews the biology underlying the effects of various fluids on the body and how sepsis disrupts the body’s natural response to corticosteroids. We also discuss the major points from these four new papers in the March 1, 2018 issue of NEJM and prior literature to get you up to speed on the evidence behind practice.2018-03-0147 min