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Mendelspod PodcastMendelspod PodcastFrom Discovery to Translation: Bruker's Bold New Play in Spatial with Joe Beechem and Oliver Braubach“We’re going to be rewriting the textbooks on how tissues work.”In this compelling reunion with spatial biology pioneer Joe Beechem and a first-time visit from Oliver Braubach, we explore the rapid evolution of spatial technologies at Bruker, a legacy instrumentation company newly resurgent in the spatial space. Following Bruker’s acquisition of Nanostring and Canopy, the company has emerged as a unifying platform where whole-transcriptome discovery meets translational assay development—under one roof.* 0:00 Red alert: we don’t yet understand how tissue biology works, and don’t let anyone tell you we do.* 5:12 Cu...2025-07-1035 minAUTM on the AirAUTM on the AirAdapting to Change: Insights on Europe’s Unitary Patent System with Robert Alderson and Mariella MassaroIn 2024, the European patent system is undergoing one of its most significant transformations in decades. The introduction of the Unitary Patent and the Unified Patent Court is reshaping how intellectual property is protected and enforced across Europe. For innovators and businesses alike, this marks a pivotal moment—one that promises streamlined processes but also introduces new complexities. Today, we’re exploring what these changes mean and how they might impact the future of innovation.  Joining me for this fascinating discussion are two renowned experts in intellectual property law, Robert Alderson and Mariella Massaro, partners at Berggren, a leadin...2024-12-1144 minthe weekly seattlethe weekly seattleweek of july 22: Kathy Surace-Smith - formerly NanoStringTop Stories:1. NanoString updatePrevious articles: ⁠⁠PSBJ article ⁠& ⁠PSBJ article⁠2. MOD Pizza sells⁠Eater article⁠3. Aquarium to open⁠Seattle Times article ⁠⁠Video⁠4. Discrimination lawsuit⁠Geekwire article⁠5. Costco raising fees⁠Seattle Times article⁠About guest co-host Kathy Surace-Smith - former SVP, Human Resources & Legal Affairs, NanoString:Kathy has over 35 years of experience working in high-growth private and public companies in US and Europe including over 20 yrs working in life sciences industry. She was the board chair for Fred H...2024-07-2134 minThe Greenshoots Intellectual Property PodcastThe Greenshoots Intellectual Property Podcast35. One year of the Unified Patent Court – what’s been filed? Statistics, three notable cases & commentaryAppleyard Lees patent attorneys Kate Hickinson and Edward Rainsford discuss: (03:46) statistics – what has been filed at the UPC so far – types of cases and industries; notable cases including (06:15) Meril Italy srl v. Edwards Lifesciences Corporation (simultaneous revocation claims in multiple UPC divisions (Munich and Paris) and definition of ‘the same parties’ under Articles 46 and 47, illegalities of subsidiaries and parent company liability, and treatment of revocation action by Munich v. Paris divisions): (17:34) Ocado Innovation Limited v. Autostore et al. and Ocado Innovation Limited v. Respondent (access to evidence and pleadings from a previously settled case, guidance re: composition of Court of Appeal...2024-05-1536 minYou, me & the UPCYou, me & the UPCEp 6: Preliminary InjunctionsIn this episode of You, me & the UPC, Charlie French and Naomi Hazenberg cover the eight UPC preliminary injunction (PI) decisions to date. They discuss the legal points that have emerged from the various inter partes PI decisions, including the Court of Appeal decision in 10x Genomics v NanoString and the recent decision from the Düsseldorf Local Division in 10x Genomics v Curio, as well as ex parte PIs and the impact of filing a protective letter in the UPC.Note: the UPC Court of Appeal’s decision in Vusion Group SA (formerly SES-imagotag SA...2024-05-1324 minthe weekly seattlethe weekly seattleweek of april 29: James Falzone - Cornish College of the ArtsTop Stories:1. Nanostring is bought⁠PSBJ article⁠2. Non-compete clauses are banned⁠Seattle Times article⁠3. Cornish is selling Kerry Hall⁠Seattle Magazine article⁠4. Music venues opening/re-opening⁠Seattle Times article⁠ (Carnation)⁠Seattle Refined⁠ (Conor Byrne)5. President of Wizards of the Coast resigns⁠Geekwire article⁠ About co-host: James Falzone - Dean at Cornish College of the Arts James Falzone is a clarinetist, composer, and improviser whose work in the jazz and creative music scenes has won him international ac...2024-04-2840 minGENOOMILINEGENOOMILINE#62 PGx kulu, meeDNA, mikroobid ja surnud, HiDefseq, ILMN, Invitae ja Nanostring (00:24) Rekord Osalemine 2023. aasta Eesti vähisõeluuringutes  (03:18) Farmakogeneetiline analüüs depressiooni raviks (05:15) Mee DNA-test võltsimise vastu mesinduses (07:07) Mikroobid ja surnukehade lagunemine - uus surma tuvastamise CSI viis? (08:51) Long Read sekveneerimine ja metülatsioonianalüüs (10:28) HiDEF-seq: genoomimutatsioonide analüüs (12:45) Single Technologies'i 3D sekveneerimisseade (13:51) Illumina lobitöö kongressis (14:56) Labcorpi Invitae varade omandamine (15:43) NanoString Technologies'i Brukeri omandamine 2024-04-2516 minTouching BaseTouching BaseNanoString Finds a Buyer, Slide Tags Enter in Early Access as Curio Trekker, Cellares Unveils Cell Therapy Manufacturing Platform Episode 13 (March 15, 2024): This week, the GEN editors discussed business news from NanoString, Curio, and Cellares. Featuring Alex Philippidis (Senior Business Editor, GEN), Uduak Thomas (Senior Editor, GEN), Jonathan Grinstein, PhD, (Senior Editor, GEN), and moderated by Corinna Singleman, PhD, (Managing Editor, GEN and IPM). Listed below are key references to the GEN stories, media, and other items discussed in this episode of Touching Base: The State of Omics 2024 Registration GEN Summit NanoString Agrees to be Acquired by Investment Firm for $2...2024-03-1524 minSpatial NavigatorSpatial NavigatorKirsty Short & Arutha Kulasinghe - Unveiling the Past: Exploring Immune Responses to the 1918 Influenza Virus through Spatial MultiomicsPresenting a recorded conversation from AGBT, where we engage in dialogue with two esteemed guests from the University of Queensland. Collaborating in the realm of virology, they possess a distinctive and invaluable collection of samples—the ones from the 1918 Spanish flu.In this episode, discover the compelling reasons behind the partnership between a virologist and a spatial omics expert. Together, they embark on a mission to address a pivotal question: Can spatial multiomics be applied to historical samples to unravel the unique aspects of the immune response to the 1918 influenza virus in young adults?2024-03-0321 minTouching BaseTouching BaseCRISPRed Pigs, Exscientia Fires CEO, & AGBT Roundup; Christian HenryEpisode 9 (February 16, 2024): Using CRISPR-Cas9 technology, British animal genetics firm Genus has generated a population of pigs that are resistant to the deadly porcine reproductive and respiratory syndrome (PRRS) virus. Exscientia has fired its founder, CEO, and principal executive officer Andrew Hopkins, PhD, and removed him from the company’s board, after it concluded that he engaged in “inappropriate” relationships with two employees. Julianna LeMieux, PhD, Deputy Editor in Chief at GEN, provides a recap of her time at AGBT 2024.Plus, an interview with Christian Henry, president and chief executive officer at PacBio. Listed below a...2024-02-1643 minPeerView Clinical Pharmacology CME/CNE/CPE VideoPeerView Clinical Pharmacology CME/CNE/CPE VideoJoyce O’Shaughnessy, MD - Custom Care Compass: Mastering Multifactorial Clinical Decision-Making in High-Risk HR+, HER2- MBCThis content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/CPE/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/RRR865. CME/MOC/NCPD/CPE/AAPA/IPCE credit will be available until February 9, 2025.Custom Care Compass: Mastering Multifactorial Clinical Decision-Making in High-Risk HR+, HER2- MBC In support of improving patient care, PVI, PeerView Institute for...2024-02-1356 minPeerView Oncology & Hematology CME/CNE/CPE Audio PodcastPeerView Oncology & Hematology CME/CNE/CPE Audio PodcastJoyce O’Shaughnessy, MD - Custom Care Compass: Mastering Multifactorial Clinical Decision-Making in High-Risk HR+, HER2- MBCThis content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/CPE/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/RRR865. CME/MOC/NCPD/CPE/AAPA/IPCE credit will be available until February 9, 2025.Custom Care Compass: Mastering Multifactorial Clinical Decision-Making in High-Risk HR+, HER2- MBC In support of improving patient care, PVI, PeerView Institute for...2024-02-1356 minPeerView Oncology & Hematology CME/CNE/CPE Video PodcastPeerView Oncology & Hematology CME/CNE/CPE Video PodcastJoyce O’Shaughnessy, MD - Custom Care Compass: Mastering Multifactorial Clinical Decision-Making in High-Risk HR+, HER2- MBCThis content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/CPE/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/RRR865. CME/MOC/NCPD/CPE/AAPA/IPCE credit will be available until February 9, 2025.Custom Care Compass: Mastering Multifactorial Clinical Decision-Making in High-Risk HR+, HER2- MBC In support of improving patient care, PVI, PeerView Institute for...2024-02-1356 minPeerView Clinical Pharmacology CME/CNE/CPE Audio PodcastPeerView Clinical Pharmacology CME/CNE/CPE Audio PodcastJoyce O’Shaughnessy, MD - Custom Care Compass: Mastering Multifactorial Clinical Decision-Making in High-Risk HR+, HER2- MBCThis content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/CPE/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/RRR865. CME/MOC/NCPD/CPE/AAPA/IPCE credit will be available until February 9, 2025.Custom Care Compass: Mastering Multifactorial Clinical Decision-Making in High-Risk HR+, HER2- MBC In support of improving patient care, PVI, PeerView Institute for...2024-02-1356 minTouching BaseTouching BaseIntellia and Ultragenyx’s Clinical Updates, Novo Holdings’ Catalent Acquisition, and NanoString Bankruptcy; Simon BarnettEpisode 8 (February 9th, 2024): Intellia and Ultragenyx gave updates on their clinical trials for gene therapies for inherited rare diseases. Novo Holdings, which manages the assets of the foundation that controls Novo Nordisk, agreed to buy Catalent for $16.5 billion to keep up with the high demand for its hit drugs Wegovy and Ozempic. Spatial biology tools developer NanoString Technologies filed for bankruptcy, blaming the $31 million jury award assessed against it last November in a patent infringement case filed by rival 10x Genomics. Plus, an interview with Simon Barnett, research director at Dimension. Listed below are key r...2024-02-0944 minGENOOMILINEGENOOMILINE#58 AI, Atrandi, Ultima Genomics, Illumina, NanoString(00:23) Uuring: Tehisintellekt suudab kiiresti ennustada antidepressantide mõju (01:27) NCCN ei soovita ctDNA-d käärsoolevähi jälgimiseks (02:17) Kliinilise labori omanik mõisteti vangi pettuse eest (03:18) Bioscientia käivitab kliinilise PacBio Hifi WGS testi (04:12) Atrandi Biosciences tutvustab mikrofluidikaplatvormi mikroobide DNA sekveneerimiseks (05:12) BGI Group kritiseerib Biosecure Act'i (06:04) Illumina tutvustab NovaSeq X-seeria 1,5B Flow Celli (07:05) Ultima Genomics toob turule suure läbilaskevõimega sekvenaatori (11:35) N6 Tec'i iconPCR uuendus pakub paindlikku PCR-i (12:54) VoltaLabs esitleb Callisto seadet DNA ekstraheerimiseks ja raamatukogu ettevalmistamiseks (14:25) Biomodal uuendab epigeneet...2024-02-0817 minSpatial NavigatorSpatial NavigatorWill Howat & Alyssa Rosenbloom - the story behind the GeoMx IO Proteome Atlas developmentListen to Will Howat, Vice President of Validation & Technical Quality at Abcam and Alyssa Rosenbloom, Associate Director of Research Proteomics discuss how the GeoMx IO Proteome Atlas panel was developed and validated as part of the Abcam-NanoString partnership. Tune in to this episode and get ready to investigate the expression of 570+ human protein targets on one slide.2024-01-0914 minSpatial NavigatorSpatial NavigatorAdam Bates & Matthew Bottomley - Dissecting the role of the immune system in skin and lung cancer with spatial biologyListen how spatial biology brought together a nephrologist and a cancer research graduate student from the University of Oxford to help each other dissect the role played by the immune system in skin and lung cancer and open the way for new immuno-therapy drug targets.2023-12-0524 minSpatial NavigatorSpatial NavigatorDavid Krull - the power of mentoring, networking and collaborations, lessons from the GeoMx® DSP Best Practices Guidance ConsortiumIn this episode, we talked to David Krull, Associate Director at GSK, leading the cellular biomarkers team. He told us about his passion for coaching and mentoring and how vital networking and collaborations have been for his career. We discussed how pharmaceutical companies are embracing tissue profiling technologies and David shared his views on applying spatial omics for biomarker discovery.2023-11-0749 minSpatial NavigatorSpatial NavigatorAlessia Ciarrocchi - Spatial transcriptomics at the service of translational oncologyIn this new spatial navigator episode, we speak to a spatial pioneer, Pr. Ciarrocchi Professor at the Azienda Unità Sanitaria Locale and Cancer Research institute of Reggio Emilia, who shares her passion for translational oncology and how she got started as group leader. During this podcast, we learn how her current work on spatial transcriptomics to dissect pleural mesothelioma heterogeneity directly serves her community. Listen to the episode to learn more about mesothelioma pathology, immune/inflammatory processes and biomarker discovery.2023-10-0340 minOncology News Central Peer-SpectivesOncology News Central Peer-SpectivesThe Quest to Cure CLL: “Remarkable” Results With New StrategyRecent advances have provided new options for when and how best to treat patients with chronic lymphocytic leukemia (CLL). Trials of combination strategies have shown promise in providing patients the potential for unmaintained remissions. Marco Ruella, MD, an assistant professor of medicine in hematology-oncology at the Perlman School of Medicine at the University of Pennsylvania and scientific director of the lymphoma program, speaks with Robert Figlin, MD, the Steven Spielberg Family Chair in hematology-oncology at Cedars-Sinai Cancer Center in Los Angeles, about the current state of CLL care and what changes are likely in the near future. Although satisfied i...2023-09-0616 minOncology News Central Peer-SpectivesOncology News Central Peer-SpectivesThe Quest to Cure CLL: “Remarkable” Results With New StrategyRecent advances have provided new options for when and how best to treat patients with chronic lymphocytic leukemia (CLL). Trials of combination strategies have shown promise in providing patients the potential for unmaintained remissions. Marco Ruella, MD, an assistant professor of medicine in hematology-oncology at the Perlman School of Medicine at the University of Pennsylvania and scientific director of the lymphoma program, speaks with Robert Figlin, MD, the Steven Spielberg Family Chair in hematology-oncology at Cedars-Sinai Cancer Center in Los Angeles, about the current state of CLL care and what changes are likely in the near future. Although satisfied i...2023-09-0616 minSpatial NavigatorSpatial NavigatorSarah Best and Saskia Freytag - Dissecting high-grade glioma spatiallySarah Best and Saskia Freytag are laboratory heads at the Brain Cancer Research Lab in Australia's Walter and Eliza Hall Institute of Medical Research.In this podcast episode, they share their views and interest for tackling high-grade glioma by dissecting its heterogeneity and its interactions with the microenvironment. They also discuss why Spatial Biology was key to uncover subtype-specific heterogeneity and how they combined the power of GeoMx DSP and CosMx SMI to maximize their understanding of this cancer type. At the end of the episode, they comment on the future of spatial multiomics, why location matters and how...2023-09-0535 minSpatial NavigatorSpatial NavigatorMirranda Orr, PhD - Alzheimer’s Disease, cellular senescence and spatial biologyIn this episode we talk about Dr. Orr’s research on the effects of tau accumulation on cellular senescence and how leveraging spatial biology with both GeoMx DSP and CosMx SMI teaches us more about the biology of neurodegenerative diseases than we have learned in the past 10 years.This podcast includes information regarding worldwide products and services, not all of which are available in every country.2023-08-0149 minThe 7investing PodcastThe 7investing Podcast3 Hidden Gems in Biotechnology with Manisha SamyFor risk-tolerant investors who love a good thrill, there are few industries more exciting than biotechnology. He Jiankui shocked the world in 2018 by announcing he'd genetically modified twins born in China. Two years later, Jennifer Doudna and Emmanuelle Charpentier shared the Nobel prize for developing CRISPR, and a globally-coordinated effort was embracing Moderna's innovative new mRNA approach to develop a COVID vaccine and make it universally available. Gene editing found its way into the clinic, enabling a new wave of checkpoint inhibitors to help the body proactively find and detect cancer. A more comprehensive understanding of the...2023-07-2539 minSpatial NavigatorSpatial NavigatorCheryl London, PhD - Humanity's best friend, a tale of two species.Dogs are man's best friend, but more than companions, in veterinary science, dogs are being studied to develop better cancer treatments that can translate to the clinic. Today we talk to Dr Cheryl London from Tufts University. She is a Veterinarian and a Vet Oncologist. We discuss how and why canines are used as model animals for cancer and how she worked with NanoString as a part of a consortium to develop the Canine IO panel on the nCounter and the hot-off-the-press Canine Cancer Atlas on the GeoMx.This podcast includes information regarding worldwide products and services...2023-06-3042 minSpatial NavigatorSpatial NavigatorDana Mustafa Ph.D. - Passion, Pancreatic Cancer and the Power of Research"I am passionate about my work because I want to find new ways to improve the lives of cancer patients." - Dr. Dana MustafaIn this episode, we talk to Dr. Dana Mustafa, a cancer researcher at Erasmus University Rotterdam. Dr. Mustafa discusses her research on pancreatic cancer and brain metastasis, and she shares her insights on the challenges and opportunities of cancer research. She also offers advice to young aspiring researchers who want to make a difference in the fight against cancer.Dr. Mustafa is a passionate and dedicated researcher who is committed to...2023-05-1531 minThe Armen ShowThe Armen Show395: Leroy Hood & Nathan Price | Personalized Predictive Health In “The Age of Scientific Wellness” A world-renowned scientist and recipient of the National Medal of Science in 2011, Dr. Leroy Hood co-founded the Institute for Systems Biology (ISB) in 2000, served as its first President from 2000-2017 and is a Professor and Chief Strategy Officer. In 2016, ISB affiliated with Providence where Dr. Hood now serves as Emeritus Science Advisor. He received his MD from Johns Hopkins University School of Medicine and his PhD in biochemistry from Caltech. Dr. Hood was a faculty member at Caltech from 1967-1992, serving for 10 years as the Chair of Biology. During this period, he and his colleagues developed four...2023-05-1054 minSpatial NavigatorSpatial NavigatorQuan Ngyuen Ph.D. - Decoding the Future: Transcriptomics, Machine Learning, and Spatial Biology DataOn today's episode, we talk to Dr. Quan Ngyuen. He is a renowned genomics and machine learning expert, leading the GML lab at IMB, University of Queensland. Focused on cancer-immune cells and neuroinflammation, he strives to improve diagnosis and treatments through single-cell analysis and spatial analysis of tissue.We discuss his experience working with multiple spatial technologies, his thoughts on data analysis, and its best practices. We also get his wishlist for both spatial instruments and the larger research community.This podcast includes information regarding worldwide products and services, not all of which are available...2023-04-1130 minSpatial NavigatorSpatial NavigatorNina Radosevic-Robin, MD - Perspectives of a Bio-PathologistDr. Radosevic-Robin is a surgical and molecular pathologist at the Jean Perrin Comprehensive Cancer Center in Clermont-Ferrand, France, She is a senior translational oncology scientist (which includes being a cell biologist too) within the Center and within the Research Unit 1240 of INSERM, The French National Institute for Health & Disease Research and lastly, she is an Associate Research Professor at the University Clermont Auvergne in Clermont-Ferrand, France.We have a great conversation on why understanding heterogeneity is important, the benefits she sees in using curated panels of the nCounter, and her opinions on the GeoMx DSP and how...2023-03-1039 minSpatial NavigatorSpatial NavigatorAzucena Salas Ph.D. - Teasing apart the possible mechanisms behind Inflammatory Bowel Diseases with single-cell spatial transcriptomics.Ulcerative Colitis (UC) & Crohn's Disease (CD) are chronic Inflammatory Bowel Diseases that have significant effects on patients. They are notoriously hard to treat due to (but not limited to) the following reasons:Chronic and Relapsing Nature: Both UC and CD are chronic diseases that can have unpredictable and relapsing symptoms, making it difficult to maintain long-term control of the condition.The complexity of the disease: The underlying mechanisms that cause UC and CD are not fully understood, and the diseases can affect different parts of the digestive tract in different ways, making it challenging to...2023-02-0754 minSpatial NavigatorSpatial NavigatorAnkur Sharma Ph.D. - The Onco-fetal EcosystemDr. Sharma's lab focuses on the onco-fetal reprogramming of cancer tissue. In this episode, we discuss his fascination with evolution and these cancer cells which seemingly recall programs from organogenesis a "cell memory", particularly in the liver. We also talk about his thoughts on the upcoming in situ platforms and the data he gathered from his CosMx SMI experiment.This podcast includes information regarding worldwide products and services, not all of which are available in every country.2023-01-0529 minSpatial NavigatorSpatial NavigatorRichard Klinghoffer Ph.D. - Presage Biosciences – Comparative In Vivo OncologyWe talk to Richard Klinghoffer Ph.D., CEO and CSO of Presage Biosciences. Presage’s Comparative In Vivo Oncology (CIVO™) system administers micro-doses of multiple drugs and/or combinations simultaneously to distinct trackable positions within a solid tumor. The tumor is then resected and analyzed to understand the microenvironment response to each spatially defined region of exposure. This is in a bid to evaluate early investigational stage cancer drugs in the most relevant context – the cancer patient, without exposing the patient to toxic effects associated with systemic delivery. We talk to Rich about his journey to Presage, the nuances betwee...2022-12-0636 minSpatial NavigatorSpatial NavigatorWilliam Hwang MD, Ph.D, Jason Reeves Ph.D – Discoveries in the pancreas and asking great questions of your experiments and your technology platform.What are the considerations when choosing a technology platform? How can we harness knowledge from other biology to increase our understanding of cancer and other diseases?Dr. William Hwang worked closely with Dr. Jason Reeves' team at NanoString for his publication that made the August cover of Nature Genetics. We discuss the findings of that publication on pancreatic ductal adenocarcinoma and the importance of asking good questions. He also shares how he connects information from seemingly unrelated fields to advance discovery.This podcast includes information regarding worldwide products and services, not all of which are...2022-10-3143 minSpatial NavigatorSpatial NavigatorArutha Kulasinghe - From Cancer to COVID, translating spatial data into actionable targets.Since the beginning of the pandemic, skeptics have been saying that a SARS-CoV2 infection is like getting the flu... but is that true? Arutha shares his spatial data comparing Influenza-A lung tissue and SARS-CoV2 lung tissue. The results led to the development of a predictor of disease severity for COVID-19. We further discuss the workflow of moving from discovery to translation. Arutha also shares his thoughts on asking the right spatial questions and collaborating with pathologists to navigate and map tissues.This podcast includes information regarding worldwide products and services, not all of which are available in...2022-10-1123 minSpatial NavigatorSpatial NavigatorAndrogenetic Alopecia, a hairy topic - Saranyoo Ponnikorn, Ph.D. & Sasin Charoensuksira, M.D.Androgenetic alopecia is the loss of terminal hair affecting up to 50% of males and 25% of females at age 50. The skin is a complex organ that seems to have its own ecology, how do we understand the factors causing alopecia? Dr Saranyoo Ponnikorn and Dr Sasin Charoensuksira used Digital Spatial Profiling to identify cell populations in individual follicles to understand the mechanisms of the condition.This podcast includes information regarding worldwide products and services, not all of which are available in every country.2022-09-0436 minSpatial NavigatorSpatial NavigatorViREMiCs, a lab for vaccine development against Flaviviruses - Eugenia Ong Ph.D. & Chan Kuan Rong Ph.D.What goes into the development of a vaccine? Why are some viruses so hard to weed out? We speak to Dr. Eugenia Ong and Dr. Chan Kuan Rong to see how their lab works to develop biomarkers and test the efficacy of developed vaccines. We further discuss the vaccine development landscape in a post-covid world.Nanostring's Social Platforms:Twitter: https://bit.ly/3qVLXyTInstagram: https://bit.ly/3uOSyfHLinkedin: https://bit.ly/3DB7j9PNanostring's Website: https://nanostring.com/This podcast includes information regarding worldwide products an...2022-07-3127 minSpatial NavigatorSpatial NavigatorAndrea Pavesi, Ph.D. & Maxine Lam, Ph.D. - Organoids, the recapitulation of Liver and Brain tissue through in vitro models.What if we could test drugs and immunotherapies on copies of human tumors on a glass slide? While animal models have been indispensable in the study of disease and therapeutics, they can be incredibly expensive, time consuming, and often do not entirely reflect human biology.Dr. Andrea Pavesi and Dr. Maxine Lam are looking to change that, producing vascularized tumor organoids at scale in microfluidic devices that recapitulate specific human disease.Nanostring's Social Platforms:Twitter: https://bit.ly/3qVLXyTInstagram: https://bit.ly/3uOSyfHLinkedin: https://bit.ly/3DB7...2022-06-3047 minSpatial NavigatorSpatial NavigatorSwati Ranade Ph.D. - The Spatial Organ Atlas and a trip through the history and future of genomics.Genomics has come such a long way - from radioactive gels, Sanger sequencing, NGS, Single-cell, and now Spatial Transcriptomics. Swati Ranade's career has spanned nearly all of it. She recalls the work she did for her Ph.D. and has always found herself at the bleeding edge of biology. She talks about the Spatial Organ Atlas and how it's a launch platform for biologic discoveries and will drive a deeper understanding of diseases.The Spatial Navigator Podcast seeks to share how Spatial Biology is revolutionising the understanding and the improvement of the human condition.Nanostring's...2022-06-0229 minSpatial NavigatorSpatial NavigatorMatilde Balbi, Ph.D. & Cong Wang, Ph.D. - Stroke and the Therapeutic Race Against TimeStroke is the number 2 cause of death worldwide and cases that are not fatal potentially change a patient's perception, personality, and physical mobility. Matilde Balbi, Ph.D., and CongWang, Ph.D. from the Queensland Brain Institute (QBI) study stroke and seek to understand whether neuromodulation can assist recovery and prevent further damage to the brain.This podcast includes information regarding worldwide products and services, not all of which are available in every country.2022-05-0130 minMendelspod PodcastMendelspod PodcastA New Generation Comfortable Doing a Thousand Things at a Time Is Reinventing Life Science Says Joe Beechem of NanoString“I’ve seen a lot of revolutions. Now we’re at the beginning of spatial biology, and I think it has the chance to transform life science similar to next gen sequencing, but even more. It’s going to have more ramifications that spread through more disciplines than any of the revolutions I’ve seen in a while.” This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.mendelspod.com/subscribe2022-04-0739 minSpatial NavigatorSpatial NavigatorElizabeth Schneider PhD - GRANTing insight into Neuroscience and Infectious DiseasesOn this episode we talk to Elizabeth Schneider, PhD. She was among the first in the USA to contract COVID-19 and shares her experience with the disease, and how it intertwined subsequently with her work. We discuss how Nanostring has changed over the last 5 years, her work on the neuroscience and infectious disease portfolio, and chat about her work on grants, enabling researchers to have access to phenomenal data through the GeoMx and nCounter platforms.The Spatial Navigator Podcast seeks to share how Spatial Biology is revolutionising the understanding and the improvement of the human condition.2022-04-0439 minSpatial NavigatorSpatial NavigatorRuby Huang MD, PhD - The Campaign Against Ovarian CancerThe symptoms of ovarian cancer can mimic other conditions and thus tends to result in late diagnoses (Diagnosis at stage I or II happens under 20% of the time). In our pilot episode, we commemorate International Women's Day with Dr Ruby Huang PhD. She has studied Ovarian cancer and talks to us about the challenges the scientific community faces in the treatment and study of the disease. She takes some time to address the gaps in the understanding of female-centred and female related conditions and charts a roadmap towards equity in that regard.The Spatial Navigator Podcast seeks to...2022-03-0744 minThe Inquiring Mind PodcastThe Inquiring Mind Podcast26. Is Modern Medicine Misguided? with Dr. Leroy HoodLeroy (Lee) Hood is a world-renowned scientist and recipient of the National Medal of Science in 2011 from President Barack Obama.  Dr. Leroy Hood co-founded the Institute for Systems Biology (ISB) and currently serves as the Chief Strategy Officer and Professor at ISB. He is a member of the National Academy of Sciences, the National Academy of Engineering, and the National Academy of Medicine. Of the more than 6,000 scientists worldwide who belong to one or more of these academies, Dr. Hood is one of only 20 people elected to all three. He has received 18 honorary degrees from prestigious universities in...2021-07-301h 16The Long Run with Luke TimmermanThe Long Run with Luke TimmermanEp92: Brad Gray on Spatial BiologyNanoString Technologies CEO Brad Gray on tools for spatial biology.2021-06-011h 11Mendelspod PodcastMendelspod PodcastOut of the Reductionist Trap: Brad Gray of NanoString on Spatial BiologyOne of the hottest new trends in biomedical research today is what is known as spatial biology--the ability to capture tissues in a 3D context. It was named Method of the Year by Nature Magazine in 2020.And one of the first automated instruments launched in this market was the GeoMx Digital Spatial Profiler by NanoString. CEO Brad Gray is here to tell us the story of the birth of the DSP and the revolution of 3D biology. What will these new tools enable for the basic and translational researcher? This is a public episode. If you'd like t...2021-05-1927 minListen to Gynecologic OncologyListen to Gynecologic OncologyJanuary 2020 Editor’s Choice - Does the transcriptome of ovarian neoplasms provide insight into its potential behavior?Editor's Choice Paper: Genomic heterogeneity in peritoneal implants: A differential analysis of gene expression using nanostring Human Cancer Reference panel identifies a malignant signature Editorial Paper: Not All Peritoneal Implants Are Created EqualHosted by: Dr. David Cohn, Deputy Editor Featuring: Dr. Cohn, Dr. Fauceglia, Dr. Shih2020-01-3000 minJournal of Clinical Oncology (JCO) PodcastJournal of Clinical Oncology (JCO) PodcastIntratumoral Immune Infiltration in Follicular Lymphoma: Novel Insights into Early Relapse and SurvivalTRANSCRIPT This JCO Podcast provides observations and commentary on the JCO article “Progression of Disease Within 24 Months (POD24) in Follicular Lymphoma Is Associated With Reduced Intratumoral Immune-Infiltration” by Dr. Tobin and colleagues. My name is Dr. Carla Casulo, and I am Associate Professor of Medicine, Hematology and Oncology at the Wilmot Cancer Institute of the University of Rochester in Rochester, NY, USA. My oncologic specialty is Lymphoma.   Follicular lymphoma is the most frequently occurring indolent non-Hodgkin lymphoma and has a long natural history, with median overall survival nearing two decades. Patients with follicular lymph...2019-12-0111 minGEN PodcastsGEN PodcastsNanostring Podcast with David Rimm, MD, PhDNanostring Podcast with David Rimm, MD, PhD by Genetic Engineering and Biotechnology News Hosted on Acast. See acast.com/privacy for more information.2019-07-0308 minIncreasingly Critical Role of Predictive Biomarkers in Cancer ImmunotherapyChief Medical Officer at nanoString Technologies, Dr Alessandra Cesano, brings to light the increasingly critical role of predictive biomarkers in cancer immunotherapy, originally presented during the translational science and new technologies session from 2017’s Immuno-Oncology 360° conference. Save the date for the 4th annual IO360° conference, taking place February 7-9, 2018 in New York City. About Dr Cesano: Alessandra Cesano, MD, PhD has served as CMO at nanoString since July 2015. Prior to joining the company, Dr Cesano was Chief Medical Officer at Cleave Biosciences, Inc. From 2008 to 2014, she served as Chief Medical Officer and Chief Operations Officer at Nodality, Inc, where she built and...2017-06-2023 minPharmaTalkRadioPharmaTalkRadioIncreasingly Critical Role of Predictive Biomarkers in Cancer ImmunotherapyChief Medical Officer at nanoString Technologies, Dr Alessandra Cesano, brings to light the increasingly critical role of predictive biomarkers in cancer immunotherapy, originally presented during the translational science and new technologies session from 2017’s Immuno-Oncology 360° conference. Save the date for the 4th annual IO360° conference, taking place February 7-9, 2018 in New York City. About Dr Cesano: Alessandra Cesano, MD, PhD has served as CMO at nanoString since July 2015. Prior to joining the company, Dr Cesano was Chief Medical Officer at Cleave Biosciences, Inc. From 2008 to 2014, she served as Chief Medical Officer and Chief Operations Officer at Nodality, Inc, where she built and...2017-06-2022 minPharmaTalkRadioPharmaTalkRadioAddressing Clinical Challenges in Immuno-OncologyOriginally recorded during the 3rd annual Immuno-Oncology 360° in February 2017, this panel discussion addresses clinical challenges within immuno-oncology. One of the IO360° lead advisors, Dr James Gulley of the National Cancer Institute, moderates the session between Merck’s Dr Roy Baynes, nanoString Technologies’ Dr Alessandra Cesano, MD Anderson’s Dr Patrick Hwu, and inVentiv Health’s Robert Millham. Dr Hwu and Dr Baynes are also speaking on the 2nd annual Rational Combinations 360° program in June 2017, which is an exciting meeting dedicated to combination therapy in IO. Save the date for the 4th annual IO360° conference, taking place February 7-9, 2018 in New York City.2017-06-2046 minAddressing Clinical Challenges in Immuno-OncologyOriginally recorded during the 3rd annual Immuno-Oncology 360° in February 2017, this panel discussion addresses clinical challenges within immuno-oncology. One of the IO360° lead advisors, Dr James Gulley of the National Cancer Institute, moderates the session between Merck’s Dr Roy Baynes, nanoString Technologies’ Dr Alessandra Cesano, MD Anderson’s Dr Patrick Hwu, and inVentiv Health’s Robert Millham. Dr Hwu and Dr Baynes are also speaking on the 2nd annual Rational Combinations 360° program in June 2017, which is an exciting meeting dedicated to combination therapy in IO. Save the date for the 4th annual IO360° conference, taking place February 7-9, 2018 in New York City.2017-06-2047 minMendelspod PodcastMendelspod PodcastBringing Home Some Diagnostics Gold: Brad Gray, NanoString Show How It’s DoneYou hear it everywhere. And it’s getting old. That "diagnostics is a tough slog.” That it’s the “redheaded stepchild of healthcare.”And today’s guest doesn’t disappoint, repeating both these phrases. But Brad Gray and NanoString can claim some big “slogging" success. They’re coming out on top in diagnostics through some clever business strategy built on a solid platform. Made CEO at just 33 years of age, Brad has taken NanoString public and overseen a successful expansion from the research to the clinical market. This is a public episode. If you'd like to discuss this with...2016-06-2418 minGRACEcast ALL Subjects audio and videoGRACEcast ALL Subjects audio and videoNanoString Treatment for Kidney CancerNanoString Technology may help doctors learn what is driving tumor growth in kidney cancer patients and, therefore, determine what treatments may be most effective for them.2014-07-2402 minGRACEcastGRACEcastNanoString Treatment for Kidney CancerNanoString Technology may help doctors learn what is driving tumor growth in kidney cancer patients and, therefore, determine what treatments may be most effective for them.2014-07-2402 minGRACEcast Kidney Cancer VideoGRACEcast Kidney Cancer VideoNanoString Treatment for Kidney CancerNanoString Technology may help doctors learn what is driving tumor growth in kidney cancer patients and, therefore, determine what treatments may be most effective for them.2014-07-2400 min