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Nicolas Verhoeven

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Nick Sterling, MD, PhDNick Sterling, MD, PhDMetabolic Health, Insulin Resistance, & Mitochondrial Health | Nicolas Verhoeven (Physionic)In this episode, I had the pleasure of sitting down with Nicolas Verhoeven of Physionic. We focus our attention on metabolic health and, specifically, the energy-related, cellular, and nutritional mechanisms of insulin resistance. Nicolas reviews evidence pertaining to the reversal of insulin resistance and dietary clinical trials demonstrating remission of type 2 diabetes. Nicolas also highlights the synergistic effects of physical activity and dietary habits on insulin resistance, expanding our discussion into mitochondrial health. Finally, we explore importance of a nuanced conversation around autophagy and its role in health and disease prevention. Physionic on YouTube: https://www.youtube.com/@Physionic ...2024-04-151h 08The Dr. Gabrielle Lyon ShowThe Dr. Gabrielle Lyon ShowPrevent Muscle Loss and Improve Mitochondrial Health | Nicolas VerhoevenNicolas Verhoeven is a PhD Candidate in Molecular Medicine who works in a mitochondria and autophagy laboratory; he also holds a Masters in Exercise Physiology. Verhoeven runs Physionic, a brand that bridges the gap between scientific studies and the public’s understanding by opening studies, showing and explaining the data, and explaining the physiology that underlies that data. One of his missions is to improve the public’s understanding of the scientific literature without sacrificing the details (or the fun!).In this episode we discuss:How to improve your mitochondrial health.The best skin supplements.Common misc...2024-01-231h 23PhysionicPhysionicHigh Fat vs High Carb Diets - Which is better for Health? (Blood Pressure, Cholesterol, Leptin, and more)In this episode, we'll be getting into a study looking at the ketogenic (high fat) diet and its comparison to a calorie restricted low fat diet on various markers of health. Study: https://academic.oup.com/jcem/article/88/4/1617/2845298 Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK62020-09-0931 minPhysionicPhysionicCan you get coronavirus more than once? Yes. [New Study]In this episode, I'll be explaining, based on a brand new case study, why the risk for re-infection is present, and what this means for the future of vaccines and herd immunity. Study: https://academic.oup.com/cid/advance-article/doi/10.1093/cid/ciaa1275/5897019 Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK62020-09-0223 minPhysionicPhysionicDo Artificial Sweeteners and Sugar cause Weight Gain and Cravings? A Study weighs in.In this episode, we cover a study investigating if 4 different artificial sweeteners (Sucralose, RebA, Saccharin, and Aspartame) cause weight gain, insulin issues, spikes in blood sugar, cravings, and more. Study: https://academic.oup.com/ajcn/article/109/5/1288/5475055 Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK62020-08-2625 minPhysionicPhysionicSupplementing Coenzyme Q10 and migraines... is there a benefit?In this episode, we'll be looking at a brief clinical trial looking at coenzyme Q10 (CoQ10, ubiquinone) and its affect on migraines in clinically evaluated migraine sufferers. If CoQ10 works, how much was used? How beneficial is it? Are there caveats? All that and more is covered here. Study: https://www.semanticscholar.org/paper/Efficacy-of-coenzyme-Q10-in-migraine-prophylaxis%3A-A-S%C3%A1ndor-Clemente/a3d4701fc58f7747a1cff3ddcd978a0794a50dc2 Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i ...2020-08-1922 minPhysionicPhysionicIs Intermittent Fasting hurtful to Heart Health? Maybe.In this episode, we'll be diving into a study investigating the role intermittent fasting has on a series of health markers, but specifically on cholesterol and blood pressure - it's not all good news, or is it? Study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2645638/ Books, Courses, and Hire Me: www.physionic.org YouTube: http://bit.ly/2JUjXVt Facebook: http://bit.ly/2PlIOaB Instagram: http://bit.ly/2OBFe7i Email List: http://bit.ly/2AXIzK6 2020-08-1228 minPhysionicPhysionicPlant and Animal Protein associations to Cancer, Heart Disease, and MortalityIn this episode, I discuss a meta-analysis looking into the associations between animal and plant based proteins, as well as total protein, and their relationships to cancer, cardiovascular disease (heart disease, stroke, etc.), and overall mortality. Is plant protein superior? Study: https://www.bmj.com/content/370/bmj.m2412 YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna02020-07-2930 minPhysionicPhysionicMaking Sense of the Microbiome, ft. Bern MonariIn this episode, I had the pleasure of having a friend and microbiome researcher Bern Monari on to educate us on the microbiome and the research therein. I hope this podcast ends up interesting, because I certainly found it to be, and Bern adds quite a bit to my knowledge of the matter. Enjoy! Bern's LinkedIn (to ask questions): https://www.linkedin.com/in/bernadinemonari/ YouTube: http://bit.ly/2JUjXVt Instagram: http://bit.ly/2OBFe7i Podcast: http://bit.ly/2PThKz0 Email Opt-In: http://bit.ly/2AXIzK6 Facebook Page (Poll Question...2020-07-2236 minPhysionicPhysionicBehind the Scenes of a CoVID-19 Vaccine, Side Effects, & Science Explained, ft. David RachIn this episode, I had the pleasure of having a fellow researcher and class mate David Rach on the podcast to discuss his experience as a participant in a CoVID-19 vaccine trial. However, not only that, he is getting his PhD in Microbiology and Immunology, so he was able to discuss some of the science behind vaccine development, as well as the preliminary results of the trial he was in. David's Info Twitter: @DavidRach2 Facebook Post on the Topic: https://tinyurl.com/yazocyla Vaccine Trial Data: https://www.medrxiv.org/content/10.1101/2020.06.30.20142570v1.full.pdf...2020-07-1535 minPhysionicPhysionicFiber, Stomach Bloating, and Potential SolutionsIn this episode, we'll be taking a look at some information on fiber, but more poignantly focused on stomach bloating and how it relates to fiber, as well as some things to consider to lower bloating from the lack or incorrect fiber intake. Fiber & Gas Study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1774297/ YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna02020-07-0819 minPhysionicPhysionicSkin Care and Ingredients that WorkIn this episode, I go on a monologue wherein I discuss the various ways skin can be damaged and become unhealthy before diving into a few habits and ingredients that have been known to aid in replenishing the health and youth of our skin. YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna0 2020-07-0131 minPhysionicPhysionicWoman Cured of Genetic Disease by Genetic Engineering - The Power of CRISPRIn this episode, I decided to dedicate some time to discussing the brand new reports that a woman suffering from sickle cell anemia has been effectively cured of the disease that would have continued to ruin her life moving forward. The cure wasn't a drug, but the first time use of genetic engineering to cure the disease. Pretty brilliant work on all involved. Article: https://www.npr.org/sections/health-shots/2020/06/23/877543610/a-year-in-1st-patient-to-get-gene-editing-for-sickle-cell-disease-is-thriving YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon...2020-06-2422 minPhysionicPhysionicBalancing Intensity for Effective Home Workouts; How Cancer evades ChemotherapyIn this episode, I discuss two topics. First, we go into how to change the intensity variable when building an effective at home workout program for muscle growth, muscle maintenance, and muscle tone. Secondly, we dive into a bit of cancer and how cancer can "hide" or protect itself against chemotherapies - how does it return? 2:48: Workout at Home 21:35: Cancer & Chemotherapy2020-06-1731 minPhysionicPhysionicUnited States Medicine in the 1800s; Zoonotic Origin of VirusesHey everyone, in this episode, I'll be going into a bit of history on how the United States handled their medical practices in the 1800s by comparison to Europe. I talk about the impact Johns Hopkins University had on the entire medical field in the United States, and then I discuss a bit on zoonotic viruses (viruses that jump from animals to humans). Medical History: 1:36 Zoonotic Virus: 23:04 YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna0 2020-06-1035 minPhysionicPhysionicSpices on Food that fight Cardiovascular Disease & Inflammation; Pain Perception in the BrainIn this episode, we'll be going into a bit of research on pain perception mediated by a particular area of the brain that wasn't pegged as one related to pain. Beyond that, do spices on food reduce inflammation and cardiovascular disease? If so, which ones? Pain (2:01): Thuy Hua, Bin Chen, Dongye Lu, Katsuyasu Sakurai, Shengli Zhao, Bao-Xia Han, Jiwoo Kim, Luping Yin, Yong Chen, Jinghao Lu, Fan Wang. General anesthetics activate a potent central pain-suppression circuit in the amygdala. Nature Neuroscience, 2020; DOI: 10.1038/s41593-020-0632-8 Spices (10:17): Connie J Rogers, Penny M Kris-Etherton, Kristina S...2020-06-0318 minPhysionicPhysionicHow much does being Overweight INCREASE Risk of Severe CoVID-19 symptoms? Why are Fit people Dying?In this episode, I go into two reviews discussing some of the data surrounding being overweight or obese and how much it increases risk of serious issues when dealing with CoVID-19. Also, why are fit people struggling with this infection, and what are some of the presented reasons/mechanisms? Review 1: https://onlinelibrary.wiley.com/doi/epdf/10.1002/oby.22842 Review 2: https://www.ahajournals.org/doi/pdf/10.1161/CIRCULATIONAHA.120.047659 YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna0 2020-05-2038 minPhysionicPhysionicUnderstanding Microbes and How Fungi impact Us, ft. Alex SoareIn this episode, I had the absolute pleasure of having yet another smart scientist on the podcast. Alex Soare is on to discuss a bit of basic immunology and microbiology for the first half of the podcast, then we dive into fungi and her expertise on mucormycosis. I hope this proves as informative as I found it (considering I knew nothing about fungi). Alex's Twitter: https://twitter.com/AlexandraYSoare National AWIS Link: https://www.awis.org/ Baltimore AWIS:  https://twitter.com/AWISBalt https://www.instagram.com/awisbaltimore/ https://www.facebook.com/AWISBaltimore/ h...2020-05-1354 minPhysionicPhysionicHow do Muscles convert Mechanical Force to Molecular signals? Well, its Confusing.In this episode, I'll (attempt) walk us through two papers that have tried to answer how our muscles convert mechanical force/stimulus into a molecular signal that produce change. It's definitely not concrete and you will have to bear with me, but we're slowly getting to an answer. YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna02020-05-0727 minPhysionicPhysionicHydroxychloroquine & Remdesivir work against CoVID-19? How?In this episode, we dive into the big two drug players on the front against CoVID-19 - hydroxycloroquine and remdesivir. Do they work? If so, how do they work? References: Remdesivir: https://www.nih.gov/news-events/news-releases/nih-clinical-trial-remdesivir-treat-covid-19-begins https://www.jbc.org/content/early/2020/02/24/jbc.AC120.013056 Hydroxycloroquine: https://www.medrxiv.org/content/10.1101/2020.03.22.20040758v3 https://www.medrxiv.org/content/10.1101/2020.04.16.20065920v2 https://www.nature.com/articles/s41584-020-0372-x https://www.nature.com/articles/s41421-020-0156-02020-04-2929 minPhysionicPhysionicHow CoVID-19 affects our Organs (other than the Lungs); Why your Mask is Ineffective and how to Fix it.In this episode, I dive into a bit of less covered information related to coronavirus CoVID-19 related to the variety of organ systems it affects and how it might be exerting it's effect. I also give some quick information on how to effectively improve your mask that you produce for yourself. Reference: https://www.sciencemag.org/news/2020/04/how-does-coronavirus-kill-clinicians-trace-ferocious-rampage-through-body-brain-toes?fbclid=IwAR1ZjxcdJiFXwSI_FfxhdBscZdT6G6jLc_RPEsnEL99CDe09_r8WE_p9VJc# https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4420971/?fbclid=IwAR3Z4zChhXgvZPXk8M0We92wrneMF9h-tSnG8hxJ4fPOj_nCMaYwnXkd09c#__ffn_sectitle2020-04-2229 minPhysionicPhysionicTranshumanism: Uploading our Consciousness for the Future, ft. Neuroscientist Garrett BunceHi everyone, this is a really special episode, because I had the absolute pleasure of having a super smart friend of mine come on the podcast to discuss a topic he's quite passionate about and on which knows a wealth of information. In this podcast, I discuss the topic of "Transhumanism" with Garrett Bunce. Transhumanism is moored in the idea of traveling consciousness beyond our current existence - can we "upload" our consciousness to a machine and continue our existence? If so, what hurdles are in the way and where are we in the process so far? Garrett takes...2020-04-1555 minPhysionicPhysionicCoronavirus Q&A; Bad Study on Effectiveness of MasksIn this episode, we'll be continuing our discussion of CoVID-19 coronavirus, as well as jumping into a bit of data in a study discussing the effectiveness of masks. Study: https://www.nature.com/articles/s41591-020-0843-2/figures/1 Video: YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna0 2020-04-0836 minPhysionicPhysionicResponding to the Coronavirus Conspiracy TheoristsIn this episode, I spend the entire time discussing the multitude of comments I have (and will) receive on my latest coronavirus video - hopefully you get some information out of it, at least. Coronavirus Video: https://www.youtube.com/watch?v=j1lcAINElzY YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna0 2020-03-2556 minPhysionicPhysionicEverything Coronavirus: How long until you show symptoms? Is a 14 day quarantine enough? How to workout in quarantine?In this episode, we will dedicate the entire podcast talking about the coronavirus (COVID-19) - how long until you show symptoms of the infection? Is a standard 14 day quarantine efficient? And, if you're stuck at home without workout equipment, how do you still make fitness progress with in resistance training? Coronavirus video (with images and data): https://youtu.be/aNqL76phkik YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna02020-03-1832 minPhysionicPhysionicThe Athlete's Paradox: The Similarity between Obesity and Athletes; Muscle & Strength, and MoreIn this episode, I cover the microbiome, as well as muscle and its relation and impact on strength gain, as well as the ever confusing "Athlete's Paradox". Microbiome: 1:48 Muscle & Strength: 10:07 Athlete's Paradox: 16:402020-03-1127 minPhysionicPhysionicLonger Pregnancy & Genetics Changes; BioInk Printing Skin; Nuances in reading Studies; Coronavirus is Local...In this episode, I cover a broad range of topics from pregnancy length and its affect on children's genetics, as well as a new technology that makes printing skin a new therapy possible. Finally, I answer a question/concern a commenter had over why scientists waste their time with "obvious questions". 1:48 - Pregnancy Merid, S.K., Novoloaca, A., Sharp, G.C. et al. Epigenome-wide meta-analysis of blood DNA methylation in newborns and children identifies numerous loci related to gestational age. Genome Med 12, 25 (2020). https://doi.org/10.1186/s13073-020-0716-9 10:37 - Printing Skin Richard...2020-03-0431 minPhysionicPhysionicHigh Protein Diets implicated in Artery Plaques; Air Pollution & Heart Attacks; Ranting on Selective BiasIn this episode, I discuss a paper looking at high protein diets and their impact on atherosclerosis, as well as air pollution and its correlation with heart attacks, and the final half is me ranting on how selective people get to fit their biases. Poor Sleep & Obesity (2:09) https://www.sciencedaily.com/releases/2020/02/200217085214.htm High Protein (7:34) https://www.sciencedaily.com/releases/2020/01/200123152614.htm Air Pollution (12:58) https://www.sciencedaily.com/releases/2020/02/200214134717.htm Selective Bias Rant (16:15) 2020-02-2633 minPhysionicPhysionicPhospholipase on Muscle Growth; Autophagy in Cancer and a Mystery Ally; New AntibioticIn this episode, we will be diving extensively into a powerful muscle promoting mechanism known as phospholipase. Following that, we dive into a potential treatment for cancer using an unlikely ally. Finally, I discuss research out of McMaster University developing a new style of antibiotic. Phospholipase (1:18) https://www.youtube.com/watch?v=EtV3yWw0hz8&t=3s Cancer & Unlikely Ally (19:20) Xue Zhang, Tingting Zhang, John N. Davis, Andrea Marzi, Anthony M. Marchese, Michael D. Robek, Anthony N. van den Pol. Mucin-like domain of Ebola virus glycoprotein enhances selective oncolytic actions against brain tumors...2020-02-1932 minPhysionicPhysionicHow does your Body fix Mutations?, Heart Rate Variability, Caffeine causes Migraines?In this podcast, I admittedly nerd out a bit on genetics and how our cells repair our genes when exposed to mutagens (things that cause mutations). However, with good reason, because a new paper has added some clarity to a part of the process and man is it cool! Beyond that, we will go into heart rate variability, as well as if caffeine is associated with migraines? Check it out and share! Rad DNA Repair, 1:03 Roxanne Oshidari, Richard Huang, Maryam Medghalchi, Elizabeth Y. W. Tse, Nasser Ashgriz, Hyun O. Lee, Haley Wyatt, Karim Mekhail. DNA...2020-02-1239 minPhysionicPhysionicThoughts on Coronavirus, New Contraceptive Technology, Marijuana & Birth, and moreIn this episode, we'll be discussing four topics: 1:47 - Coronavirus 14:46 - Contraceptive Technology 22:36 - Marijuana & Birth 28:08 - Sleep Deprivation & Hunger YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna0 2020-02-0533 minPhysionicPhysionicSpontaneous, life threatening, meat allergies; ageotyping; cellular asthma, and moreIn this week's episode, we will be discussing many subjects ranging from sudden meat allergies, how asthma presents itself (cellularly), to different "styles" of aging known as ageotypes, as well as even more! Topics and time stamps listed here: Meat Allergy (2:37): https://www.jimmunol.org/content/203/4/813 Selective Asthma (10:50): https://www.nature.com/articles/s41590-019-0496-9 Skin Pain Sensation (19:38): https://science.sciencemag.org/content/365/6454/695 Ageotypes (26:10): https://www.nature.com/articles/s41591-019-0719-5 Protein on Health (31:42): https://www.physionic.org/highproteinonhealth2020-01-2936 minPhysionicPhysionicDiet on Male Fertility, Non-HDL Cholesterol on Heart DiseaseIn this episode, we will go over three articles describing the affect genetics play on cardiovascular disease, as well as sleep's mitigating role. We will also discuss how non-HDL cholesterol affects heart disease risk. Finally, we briefly discuss a study on extreme sugar consumption and its impact on male fertility. (2:28) Genetics & Sleep: Mengyu Fan, Dianjianyi Sun, Tao Zhou, Yoriko Heianza, Jun Lv, Liming Li, Lu Qi. Sleep patterns, genetic susceptibility, and incident cardiovascular disease: a prospective study of 385 292 UK biobank participants. European Heart Journal, 2019; DOI: 10.1093/eurheartj/ehz849 (11:32) Non-HDL Cholesterol: Application of non-HDL cholesterol for population-based ca...2020-01-2232 minPhysionicPhysionic5 Laws of Health, Winning the War on Cancer, Creatine on Muscle HypertrophyIn this episode, we take a deeper look at a recent video I released on YouTube wherein I describe 5 immutable "laws" of health. Then, we will discuss two bits on cancer research - one wonderful and one interesting. Finally, we finish off with a discussion of "does creatine increase muscle mass directly?" 6:18 - 5 Laws of Health 22:12 - War on Cancer 30:00 - Ketones and Breast Cancer 40:47 - Creatine direct affect on Muscle Hypertrophy? Ketones on Cancer: https://www.physionic.org/overexpressingketonesonbreastcancer 5 Laws of Health: https://www.youtube.com/watch?v=US684eYHLMY...2020-01-1650 minPhysionicPhysionicEndometriosis: Cause of Pain? Treatments? Diagnosis? Symptoms? and More, Ft. Alyssa DotsonThis week's episode is an intriguing one as it involves an in-depth dive into the condition known as endometriosis. I am joined by Alyssa Dotson, who had endometriosis and spent several years reading up on the condition. We dive into treatment, diagnosis, her story, what endometriosis is, as well as a study that claims to have found the cause of endometriosis pain, as well as much more. Time Stamps: What is Endometriosis? (2:02) What causes Endometriosis? (3:08) Signs & Symptoms? (6:49) How long has Endometriosis been around, clinically? (19:37) Treatments for Endometriosis? (20:58) Does Endometriosis worsen? (28:35) ...2020-01-081h 07PhysionicPhysionicDogs for Mental Health, Balancing Blood pH, Sleeplessness on Food ChoicesIn this episode, you will hear a little bit on how dogs may have an effect in regards to mental health, how the body uses a particular reaction to control blood pH (acidity and alkalinity), how sleep impacts our food choices (or, the lack thereof), and more. Check it out! 3:29 - Dogs 12:09 - Blood pH 27:32 - Sleep & Food Choice 34:49 - Calorie Deficit & Lifespan Reference: Robert Yolken, Cassie Stallings, Andrea Origoni, Emily Katsafanas, Kevin Sweeney, Amalia Squire, Faith Dickerson. Exposure to household pet cats and dogs in childhood and risk of subsequent diagnosis...2019-12-2746 minPhysionicPhysionicInfrared Sauna for Heart Disease?In this episode, we dive into how infrared sauna therapy may or may not be beneficial for endothelial function/heart disease. Study, Notes, & Amendments: https://www.physionic.org/infraredsaunaforheartdisease YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna02019-12-1913 minPhysionicPhysionicA Benefit of Starting an Exercise Lifestyle EarlyIn this episode, I discuss why it is imperative to start your exercise life early in this particular regard - your bones. YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna02019-12-1805 minPhysionicPhysionicWhy does our skin age?In this episode, I describe a few different mechanisms for why our skin ages through the discovered differences between elderly skin and young skin. Study, Notes, & Amendments: https://www.physionic.org/collagenproductioninagedskin YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna02019-12-1722 minPhysionicPhysionicSelective Autophagy & Longer LifeIn this episode, I discuss some research wherein scientists have gotten some clues between autophagy and longer life based on a protein called p62. Reference: Caroline Kumsta, Jessica T. Chang, Reina Lee, Ee Phie Tan, Yongzhi Yang, Rute Loureiro, Elizabeth H. Choy, Shaun H. Y. Lim, Isabel Saez, Alexander Springhorn, Thorsten Hoppe, David Vilchez, Malene Hansen. The autophagy receptor p62/SQST-1 promotes proteostasis and longevity in C. elegans by inducing autophagy. Nature Communications, 2019; 10 (1) DOI: 10.1038/s41467-019-13540-4 YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email...2019-12-1610 minPhysionicPhysionicKlotho for Cognition and LifespanIn this episode, I describe a positive mutation that occurs in some people leading them to have enhanced cognitive ability and longer life. Study, Notes, & Amendments: https://www.physionic.org/klothooncognition YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna02019-12-1210 minPhysionicPhysionicDietary Cholesterol - Okay or Not?In this episode, we dive into dietary cholesterol and its impact on the body as it relates to increasing serum/blood cholesterol levels. YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna02019-12-1106 minPhysionicPhysionicFat Loss, Libido, and Sexual FunctionIn this episode, I take some time and explain what I've discovered in my reading of many studies on the topic and tracing the possible reasons for differences in libido and sexual function with fat loss. Article, Video, and References: https://www.physionic.org/fatlossandsexdrive [Video will be live at 11am ET today] YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna02019-12-1014 minPhysionicPhysionicThe Longest Heart Attack in History, Sensual RecalibrationIn this episode, I discuss the longest heart attack in Spanish history and how a woman SURVIVED after being "dead" for 6 hours. Not only that, I discuss research investigating the retooling of the mammalian brain network under new circumstances. Heart Attack (1:14): https://www.bbc.com/news/uk-50681489 Brain Sensing (8:42): Krystyna Solarana, Ji Liu, Zac Bowen, Hey-Kyoung Lee, Patrick O. Kanold. Temporary visual deprivation causes decorrelation of spatio-temporal population responses in adult mouse auditory cortex. eNeuro, 2019; ENEURO.0269-19.2019 DOI: 10.1523/ENEURO.0269-19.2019 YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7...2019-12-0915 minPhysionicPhysionicThe Sunshine VitaminIn this episode, I go through a dialogue I wrtoe some time ago discussing the physiology and implications of the "sunshine vitamin" (Vitamin D). YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna02019-12-0604 minPhysionicPhysionicCurcumin completely eliminates Diabetes riskIn this episode, I briefly discuss one tiny piece of high impact data wherein diabetes risk is completely eliminated by curcumin supplementation. YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna02019-12-0501 minPhysionicPhysionicDoes Metabolism REALLY slow with Age?In this episode, we will go into a bit of detail on metabolism and why it likely does not REALLY slow with age all that much. YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna02019-12-0407 minPhysionicPhysionicTumors SHARE their CancerIn this brief episode, I discuss a paper wherein the researchers discover that multiple tumors will share, or "cross pollinate" or "self-seed" themselves by sharing cancerous cells. Study, Notes: https://www.physionic.org/cancerselfseeding YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna02019-12-0302 minPhysionicPhysionicHow Metabolism determines Breathing, and PhD Qualifying ExamIn this episode, we dive into a bit of the physiology on how our tissue metabolism dictates how heavily we breathe and the interplay between the two. I also jump into a bit of my upcoming PhD qualifying exam and how some of the content going forward may be skewed in a few directions for 4-5 months. Metabolism & Breathing: 1:39 PhD Qualifying Exam: 14:19 YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna02019-12-0221 minPhysionicPhysionicHappy Thanksgiving - a Word of PositivityIn this episode, I describe why you needn’t worry over consuming a lot for Thanksgiving.2019-11-2806 minPhysionicPhysionicTaurine supplement for Triathlon, Marathon performanceIn this episode, I dissect a paper wherein I investigate the effect Taurine produces in regards to long distance exercise performance. Study, Notes, & Video: https://www.physionic.org/taurineforlongdistanceexercise Note: Video will be open to the public on 11/28 (next day from when this releases). YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna02019-11-2716 minPhysionicPhysionicMore Garlic, Less Blood Pressure?In this episode, I go into a study investigating the effect from garlic consumption on blood pressure in hypertensive individuals. Study, Notes, & Video: https://www.physionic.org/garliconbloodpressure YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna02019-11-2614 minPhysionicPhysionicLab Grown Meat Revisited, How to transition to a "Bulking" Diet, Creating your own Pre-workoutIn this episode, we will be discussing three topics (time stamps provided): 1. How is the research going on providing lab grown meat?; 2. How to transition effectively from a fat loss phase to a lean gaining phase/bulk; 3. Creating my own pre-workout and future content on it. 3:04 - Lab Meat 15:57 - Bulking Diet Transition 28:42 - Making own Pre-workout Reference: https://news.harvard.edu/gazette/story/2019/10/lab-grown-meat-gains-muscle-as-it-moves-from-petri-dish-to-dinner-plate/2019-11-2531 minPhysionicPhysionicThe Gut Microbiota and its Link to AllergiesIn this episode, I "flashback Friday" to an episode of the podcast wherein I discuss a paper on the gut microbiota's impact on allergic reactions. Reference: https://youtu.be/O5-pTKbyZvM YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna02019-11-2206 minPhysionicPhysionicFructose on Liver HealthIn this episode, I explain a bit of data on liver health as it relates to fructose consumption. Study, Notes, and Amendments: https://www.physionic.org/fructose-vs-glucose-on-inflammation YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna02019-11-2106 minPhysionicPhysionicLSD for Mental Illness & Researchers vs. FDA, ft. Bobby LeaseIn this snippet, Bobby Lease (a fellow PhD student) explains some of the potential of future LSD research and how the FDA gets in the way from time to time. Shortened Version of Data: https://youtu.be/lrCE935KF88 Full Length (with Bobby): https://youtu.be/5ljTLwLYHL4 YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna02019-11-2004 minPhysionicPhysionicHow our Circadian Rhythms control the Cells in our GutIn this episode, we go into some detail on how circadian rhythms control the division of the cells in our gut - you can follow along the paper being discussed by the link below. Study, Notes, & Amendments: https://www.physionic.org/circadianrhythmandcelldivision YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna02019-11-1926 minPhysionicPhysionicGame Changers Documentary, Living Past 110 Years, and Cardio's impact on MortalityIn this episode, we dive into a question related to the latest Game Changers controversy, what lets people live to be over 110 years old, and the impact of cardio/long distance exercise on mortality. Game Changers: 1:58 Supercentenarians: 13:25 Cardio on Mortality: 19:06 YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna0 References Supercentenarians: Kosuke Hashimoto, Tsukasa Kouno, Tomokatsu Ikawa, Norihito Hayatsu, Yurina Miyajima, Haruka Yabukami, Tommy Terooatea, Takashi Sasaki, Takahiro Suzuki, Matthew Valentine, Giovanni...2019-11-1823 minPhysionicPhysionicTalk to your doctor about FREE testosterone rather than TOTAL testosteroneIn this episode, we discuss total testosterone relative to free testosterone and why free is more telling of your endocrinology. YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna02019-11-1505 minPhysionicPhysionicSaturated Fat increases Cholesterol in ApoB Sensitive IndividualsIn this episode, we dive into a paper wherein the researchers investigated the effect seen from saturated fat intake on LDL and total cholesterol. Study, Notes, and Amendments: https://www.physionic.org/saturatedfatonapobcholesterol YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna02019-11-1419 minPhysionicPhysionic3 Minimum Moves for Health ImprovementsIn this episode, we discuss three moves a person can make to dramatically improve their health from baseline. YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna02019-11-1306 minPhysionicPhysionicCreatine Supplement protects against Brain Damage (TBI)In this episode, we get into a paper wherein creatine supplementation was used to see if it had a protective effect in brain damage (traumatic brain injury), as seen in contact sports or car wrecks. Study, Notes, Amendments: https://www.physionic.org/creatineontbi YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna02019-11-1218 minPhysionicPhysionicSleep on Anxiety, Why is there a Muscular Growth Ceiling?In this episode, we dive into two topics: First, sleep - how is it associated with anxiety? Secondly, we dive into a couple of mechanisms to explain why there is a potential for muscle growth. Reference: Eti Ben Simon, Aubrey Rossi, Allison G. Harvey, Matthew P. Walker. Overanxious and underslept. Nature Human Behaviour, 2019; DOI: 10.1038/s41562-019-0754-8 YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna02019-11-1121 minPhysionicPhysionicOptimal Timing of Protein for Health and MuscleIn this episode, we dive into how you can time your protein intake for a more productive consumption of the nutrient for better health and muscle outcomes. YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna02019-11-0804 minPhysionicPhysionicIs cognition and memory improved by Creatine supplement?In this episode, we investigate a paper wherein the outcomes are related to cognition and if consuming daily creatine positively affects cognition. Study & Notes: https://www.physionic.org/creatineoncognition YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna02019-11-0716 minPhysionicPhysionicWhat happens to dietary fat after you've eaten it?In this episode, we meld the science of nutrition and physiology to explain what happens to dietary fat when we consume it? YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna02019-11-0605 minPhysionicPhysionicMagnesium Supplementation against Muscle Cramps? Maybe Not.In this episode, we get into some of the science of magnesium supplementation and its impact on muscle cramps in more senior individuals - does it help? Paper & Notes: https://www.physionic.org/magnesiuminfusiononmusclecramps YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna02019-11-0514 minPhysionicPhysionicMedical Breakthrough for Cystic FibrosisIn this episode, we dive into a bit of the science of a new treatment that may substantially help many individuals with the debilitating and life shortening disease known as "Cystic Fibrosis". YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna02019-11-0407 minPhysionicPhysionicThe Dualism of Sleep: What causes us to fall Asleep?In this episode, we dive into what causes our brain to switch to sleep over wakefulness. YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna02019-10-3104 minPhysionicPhysionicCarbon Monoxide Poisoning - How it KillsIn this episode, we dive into some of the specifics on the pathophysiology of carbon monoxide poisoning. YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna02019-10-3103 minPhysionicPhysionicWhat does REM Sleep do for the Brain?In this episode, we discuss Rapid Eye Movement (REM) sleep and its role in our brain. YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna02019-10-3003 minPhysionicPhysionicSugar, Honey, and High Fructose Corn Syrup compared...In this episode, I dissect some of the research looking at HFCS vs sucrose vs honey and their impact on our health. Content Discussed: https://www.physionic.org/honeysugarhfcs YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna02019-10-2906 minPhysionicPhysionic2019 Nobel Prize, Your OpinionIn this episode, we dive into a bit of an explanation of this year's Nobel Prize, and in the second half, I discuss some changes to a series that has become a staple of Physionic, as well as welcoming your opinion. YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna02019-10-2817 minPhysionicPhysionicHormesis: A Little Stress Never Hurt Anyone...In this episode, I explain the concept of hormesis and its positives on health and growth. YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna02019-10-2505 minPhysionicPhysionicCaffeine likely does not impede Muscle GrowthIn this episode, I briefly describe some data on how caffeine is unlikely to decrease muscle growth. YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna02019-10-2402 minPhysionicPhysionicSame Genes, Different Cells - What Gives?In this episode, I describe why cells are different in their look, yet have the same genetic blue print. YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna02019-10-2305 minPhysionicPhysionicConsuming One Meal a Day raises Blood SugarIn this episode, I discuss how a paper I dissected illustrates how consuming one meal a day (OMAD) increases blood sugar levels compared to a more traditional diet. YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna02019-10-2206 minPhysionicPhysionicCori Cycle: The Body's Sugar RecyclingIn this episode, I discuss alternative energy substrates to glucose/sugar and fat. YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna02019-10-2107 minPhysionicPhysionicHebbian Learning: How Neurons ConnectIn this episode, I discuss how neurons strengthen their connections upon the stimulus to learn or think. YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna02019-10-1803 minPhysionicPhysionicCancers share cells and hijack our Immune SystemIn this episode, I give a summary of some of the data found in a huge paper looking at how cancerous tumors will share cells amongst one another and grow. Study, Notes, and Amendments: https://www.physionic.org/cancerselfseeding YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna02019-10-1706 minPhysionicPhysionicPhysiological Age bests Chronological AgeIn this episode, I describe what physiological age is and how it relates to the standard understanding of age known as chronological age. YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna02019-10-1605 minPhysionicPhysionicCurcumin Supplementation affects Diabetes RiskIn this episode, I discuss some data from a linked paper looking into the supplementation of curcumin in a standard diet and its potentially positive role in decreasing diabetes risk. Study, Notes, Amendments: https://www.physionic.org/curcumindiabetesrisk YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna02019-10-1523 minPhysionicPhysionicMenopause, Sleep, and the BrainIn this episode, I take a bit of time to make you aware of newly announced research on the connection between menopause, night sweats, sleep, and cognition. YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna02019-10-1409 minPhysionicPhysionic#FBF: Everything Delayed Onset Muscle Soreness (DOMS)In this episode, I take us back many months to a time when I covered the topic of DOMS for the podcast. YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna02019-10-1118 minPhysionicPhysionicDimethyltryptamine vs Anti-DepressantIn this episode, I briefly describe how Dimethyltryptamine (DMT) stacks up against the popular anti-depressant, ketamine. YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna02019-10-1001 minPhysionicPhysionicDifferences between Women & Men with Prolonged FastingIn this episode, I explore a few of the substrate/metabolic differences between men and women when it comes to prolonged/multi-day fasting. YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna02019-10-0904 minPhysionicPhysionicGene Mutations lead to Worse Blood Sugar RegulationIn this episode, I discuss, in detail, a paper looking at how our genes can impair our ability to regulate blood sugar levels through impairing insulin processing in our pancreas. Reference, Notes, & Amendments: https://www.physionic.org/geneticspax6insulin YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna02019-10-0834 minPhysionicPhysionicEffort, not weight, dictates Muscle GrowthIn this episode, I discuss an article released by the Physiological Society on muscle growth - is is weight lifted that dictates muscle size? Nope. YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna02019-10-0709 minPhysionicPhysionicFructose reduces insulin sensitivity and blood sugar tolerance..In this episode, I discuss how fructose and glucose, but mostly fructose, impact insulin levels in the blood and blood sugar levels (in rats consuming 60% of their diet from fructose, for 8 weeks). It's not great! Full Content: https://www.youtube.com/watch?v=skQ_DlspTsw YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna02019-10-0404 minPhysionicPhysionicDoing LESS work in the gym to achieve SAME strength resultsIn this episode, I discuss, briefly, how doing less sets yields comparable strength increases as doing massive amounts more volume/sets in a workout. Full Content: https://youtu.be/ANpAX7luih0 YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna02019-10-0301 minPhysionicPhysionicHow does fructose consumption affect the liver?In this episode, I discuss a few figures from a paper looking at large amounts of fructose consumption (60% of total diet for 2 months, in rats) and its impact on liver health. Full Content: https://www.youtube.com/watch?v=skQ_DlspTsw YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna02019-10-0203 minPhysionicPhysionicWhat happens to your hormones and metabolism when you fast for DAYS?In this episode, I discuss the various changes in hormones and metabolism from multi day fasting based on a series of studies I investigated in my article (linked). Reference: https://www.physionic.org/physiology-of-prolonged-fasting YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna02019-10-0105 minPhysionicPhysionicGood News for Red Wine - Maybe.In this episode, I discuss an associative study claiming that consuming red wine preferentially helped gut microbiome, as well as a few other health markers. Reference: Caroline I. Le Roy, Philippa M. Wells, Jiyeon Si, Jeroen Raes, Jordana T. Bell, Tim D. Spector. Red Wine Consumption Associated With Increased Gut Microbiota α-diversity in 3 Independent Cohorts. Gastroenterology, 2019; DOI: 10.1053/j.gastro.2019.08.024 YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna0 2019-09-3007 minPhysionicPhysionicHow much caffeine will improve cardio performance?In this episode, I give the details on how much caffeine improves cardio/long distance exercise performance. YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna02019-09-2702 minPhysionicPhysionicCreatinine - what is it? What does it tell you about your kidneys?In this episode, I go back to a slightly older piece of content wherein I discuss the molecule creatinine and what it means when you have elevated creatinine levels. YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna02019-09-2603 minPhysionicPhysionicWhat "ALT" means on your Blood Panel.In this episode, I briefly discuss what ALT stands for and what it means to your health. YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna02019-09-2502 minPhysionicPhysionicCalories are ENERGY, how do they make us gain MASS? Ft. Dean Verhoeven (My Dad)In this episode, I get the help of my father, who holds his doctorate in physics, to discuss and introduce the issue of calories being a unit of energy, so how do they impact our weight, a unit of mass. YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna0 2018-12-2431 min28 Plays Later28 Plays LaterEpisode 138 – The One With Actual Nicolas CageBecause you demanded it, Paul shares an excerpt from his interview of Nicolas Cage for the movie Mandy — plus, Destiny 2: Forsaken, and what makes an actual hero, besides murdering thousands of henchmen and for some reason sparing the head villain for courts to deal with? Also: John Wick takes …2018-09-2400 minThe Muscle Engineer PodcastThe Muscle Engineer Podcast#5 Nicolas Verhoeven, MSc - Inflammation and it's impact on muscle growth and healthIn this episode I'm joined by Nicolas Verhoeven to discuss inflammation. Nicolas is currently finishing up his Masters in Exercise Physiology, with his thesis focusing on muscle atrophy, as it relates to sarcopenia and cachexia. He runs a YouTube channel called Physionic and a blog with the same name, on which he shares evidence based information about a variety of topics related to physiology, nutrition and general health. During our conversation we tackle the controversial topic of inflammation, and it’s implications for muscle growth and health. If you’re interested in knowing what...2017-12-0957 minThe Muscle Engineer PodcastThe Muscle Engineer Podcast#5 Nicolas Verhoeven, MSc - Inflammation and it's impact on muscle growth and healthIn this episode I'm joined by Nicolas Verhoeven to discuss inflammation.Nicolas is currently finishing up his Masters in Exercise Physiology, with his thesis focusing on muscle atrophy, as it relates to sarcopenia and cachexia.He runs a YouTube channel called Physionic and a blog with the same name, on which he shares evidence based information about a variety of topics related to physiology, nutrition and general health.During our conversation we tackle the controversial topic of inflammation, and it’s implications for muscle growth and health. If you’re interested in knowing what...2017-12-0957 min