Shows
Parkinson WeeklyBonus Episode - Christmas Specialđđď¸ Weâre back with a special Christmas bonus episode of Parkinson Weekly, hosted by Prof. Bas Bloem.In this festive episode, Bas reflects on the many developments, conversations, and lessons from 2025, offering a thoughtful and wide-ranging look at where Parkinsonâs disease research and care stand today. From scientific progress and clinical practice to people, policy, and purpose, he shares his perspective on what has changed â and what still needs to evolve. Bas also looks ahead to the future, outlining his outlook on Parkinsonâs disease treatment in the years to come, with a message of rea...
2025-12-2505 minParkinson WeeklyEP 15 - Adaptive Deep Brain Stimulation (aDBS) with Special Guest Dr. Martijn Beudelđď¸ Weâre back with the fifteenth episode of Parkinson Weekly, hosted by Prof. Bas Bloem.In this weekâs episode, Bas explores the next generation of neuromodulation with a focus on Adaptive Deep Brain Stimulation (aDBS), joined by special guest Dr. Martijn Beudel. Together, they unpack how aDBS moves beyond traditional continuous stimulation by dynamically responding to a patientâs brain signals in real time. The discussion highlights the potential of this personalised approach to improve symptom control, reduce side effects, and reshape the future of Parkinsonâs disease treatment, wh...
2025-12-1818 minParkinson WeeklyEP 14 - Artificial intelligence â Great Promises & Great Concernsđď¸ Weâre back with the fourteenth episode of Parkinson Weekly, hosted by Prof. Bas Bloem.In this weekâs episode, Bas delves into the rapidly evolving world of artificial intelligence and its growing influence on Parkinsonâs disease care and healthcare in general. He explores how AI-driven tools offer remarkable new possibilities â from earlier diagnosis to personalised treatment strategies â while also highlighting the ethical, clinical, and practical concerns that come with relying on algorithms in healthcare. Bas reflects on how the promise of AI must be balanced with caution, transparency, and rigorous scientific validation.Have a que...
2025-12-1107 min
Reflections on Parkinson's DiseaseMED/PD/2025UK34: Reflections on Parkinsonâs Disease Podcast - Navigating the PD Universe S1 EP6: Impact of OFFs in patients' livesProfessors Bas Bloem and Werner Poewe discuss the impact of OFF periods in Parkinsonâs disease, exploring how they affect patientsâ daily lives and the importance of optimising treatment to reduce their burden.
2025-12-1015 minParkinson WeeklyEP 13 - Article Of The Week: Shades Of Grey: The Continuum Of Therapies For Parkinson's Disease Along The Spectrum Of Credibilityđď¸ Weâre back with the thirteenth episode of Parkinson Weekly, hosted by Prof. Bas Bloem.In this weekâs episode, Bas explores the powerful intersection between art and Parkinsonâs disease â how creativity, expression, and the artistic process can offer unique insights into living with the condition. From movement and emotion to identity and resilience, Bas reflects on the ways art can illuminate aspects of Parkinsonâs that clinical measures often overlook.The article of the week, âShades of grey: The continuum of therapies for Parkinsonâs disease along the spectrum of credibi...
2025-12-0408 minParkinson WeeklyEP 12 â Will clinical study assessments stand the test of time?đď¸ Weâre back with the twelfth episode of Parkinson Weekly, hosted by Prof. Bas Bloem.In this weekâs episode, Bas examines whether todayâs clinical study assessments are truly prepared for the future of Parkinsonâs research and care. With rapid advances in technology, emerging biomarkers, and new digital tools, long-established rating scales and outcome measures are increasingly being questioned.Do they genuinely reflect what matters most to people living with Parkinsonâs? And how might clinical studies adapt to capture the full complexity of the condition?Have a question youâ...
2025-11-2706 min
Reflections on Parkinson's DiseaseMED/PD/2025UK33: Reflections on Parkinsonâs Disease Podcast - Navigating the PD Universe S1 EP5: Non-motor symptomsProfessors Bas Bloem and Werner Poewe discuss the often-overlooked non-motor symptoms of Parkinsonâs disease, exploring their impact on patientsâ lives and the importance of recognising and managing them effectively.
2025-11-2616 minParkinson WeeklyEP 11 - Fecal Microbiota Transplantation for Treatment of Parkinsonâs Diseaseđď¸ Weâre back with the eleventh episode of Parkinson Weekly, hosted by Prof. Bas Bloem.This weekâs Article of the Week delves into the emerging role of faecal microbiota transplantation (FMT) as a potential treatment for Parkinsonâs disease.Building on growing evidence linking gut health and neurological function, the study examines whether restoring a healthy gut microbiome could help alleviate symptoms and possibly influence disease progression.đ You can read the full article below:https://jamanetwork.com/journals/jamaneurology/fullarticle/2821254Have a...
2025-11-2015 minParkinson WeeklyEP 10 - The role of lifestyle interventions in symptom management and disease modification in Parkinsonâs diseaseđď¸Weâre back with the tenth episode of Parkinson Weekly, hosted by Prof. Bas Bloem.This weekâs Article of the Week explores an exciting and rapidly evolving field of research â the potential for lifestyle interventions to not only alleviate symptoms but also influence the underlying disease process in Parkinsonâs.From exercise and diet to sleep and stress management, the discussion sheds light on how small, evidence-based lifestyle changes can make a meaningful difference in patientsâ lives â and what the latest science reveals about their role in long-term disease modificat...
2025-11-1313 min
Reflections on Parkinson's DiseaseMED/PD/2025UK32: Reflections on Parkinsonâs Disease Podcast - Navigating the PD Universe S1 EP4: Paradigm shift in the treatment of PDProfessors Bas Bloem and Werner Poewe discuss the evolving landscape of Parkinsonâs disease treatment, highlighting the paradigm shift towards earlier intervention, personalised therapy, and holistic patient care.
2025-11-1217 minParkinson WeeklyEP 9 - Bas's Book Nook!đď¸ Weâre back with the ninth episode of Parkinson Weekly, hosted by Prof. Bas Bloem.In this special episode, Professor Bas Bloem shares his top book recommendations on Parkinsonâs disease â a hand-picked selection of titles that offer insight, inspiration, and understanding for anyone affected by or interested in the condition.From personal stories and patient perspectives to the latest scientific research and clinical wisdom, Bas introduces each book with a brief description of why it stands out and what makes it a must-read.Tune in to discover which books have...
2025-11-0614 minParkinson WeeklyEP 8 - Association of ultra-processed food consumption with prodromal, incident Parkinson's disease and mortality Association of ultra-processed food consumption with prodromal, incident Parkinson's disease and mortalityđď¸ Weâre back with the eighth episode of Parkinson Weekly, hosted by Prof. Bas Bloem.This weekâs Article of the Week highlights a fascinating and innovative area of research:In this episode, Professor Bas Bloem reviews the study 'Association of ultra-processed food consumption with prodromal, incident Parkinson's disease and mortality'. Tune in as he discusses how dietary choices might influence the risk and progression of Parkinsonâs disease.đ You can read the full article below:https://pubmed.ncbi.nlm.nih.gov/40675802/Have a questio...
2025-10-3013 min
Reflections on Parkinson's DiseaseMED/PD/2025UK31: Navigating the PD Universe S1 EP3: Practical management of reemergent symptomsProfessors Bas Bloem and Werner Poewe discuss the practical management of re-emergent symptoms in Parkinsonâs disease, offering expert insights and guidance on how to recognise, assess, and address these challenges in daily clinical practice.
2025-10-2916 minParkinson WeeklyEP 7 - Beyond MIND and Mediterranean Diets: Designing a Diet to Optimize Parkinson's Disease Outcomesđď¸ Weâre back with the seventh episode of Parkinson Weekly, hosted by Prof. Bas Bloem.This weekâs Article of the Week highlights a fascinating and innovative area of research:In this episode, Professor Bas Bloem reviews the study "Beyond MIND and Mediterranean Diets: Designing a Diet to Optimize Parkinson's Disease Outcomes" Tune in as he discusses how nutrition could play a pivotal role in shaping better outcomes for people living with Parkinsonâs.đ You can read the full article below:https://www.researchgate.net/publication/39...
2025-10-2312 minParkinson WeeklyEP 6 - Hypoxic conditioning in Parkinson's disease: randomized controlled multiple N-of-1trialsđď¸ Weâre back with the sixth episode of Parkinson Weekly, hosted by Prof. Bas Bloem.This weekâs Article of the Week highlights a fascinating and innovative area of research:In this episode, Professor Bas Bloem reviews the study âHypoxic Conditioning in Parkinsonâs Disease: Randomized Controlled Multiple N-of-1 Trials.â He explores how controlled exposure to hypoxia may offer therapeutic potential in Parkinsonâs disease, discussing the study design, key outcomes, and what this could mean for future management strategies.Read here: https://www.nature.com/articles/s41467-025-63324...
2025-10-1611 min
Reflections on Parkinson's DiseaseMED/PD/2025UK9: Navigating the PD Universe - S1 EP2: Understanding the mechanisms behind PD and therapeuticsProfessors Bas Bloem and Werner Poewe explore the underlying mechanisms of Parkinsonâs disease and discuss current and emerging therapeutic approaches. A clear and insightful conversation for anyone seeking to better understand the science behind PD and its treatment.
2025-10-1416 minParkinson WeeklyEP 5 - Article Of The Week: Two Articles: Phase I trial of hES cell-derived dopaminergic neurons for Parkinson's Disease & Phase I/II of iPS-cell-derived dopaminergic cells for Parkinson's Diseaseđď¸ Weâre back with the fifth episode of Parkinson Weekly, hosted by Prof. Bas Bloem.This weekâs Article of the Week explores an exciting area of research:In this episode, Professor Bas Bloem reviews two groundbreaking studies marking a major step forward in regenerative medicine for Parkinsonâs disease: a Phase I trial of hES cell-derived dopaminergic neurons and a Phase I/II trial of iPS-cell-derived dopaminergic cells. He discusses the scientific progress, safety outcomes, and the potential of stem cell therapies to transform future Parkinsonâs treatment.đ You ca...
2025-10-0913 minParkinson WeeklyEP 4 - Article Of The Week: Proximity to golf courses and risk of Parkinsonâs diseaseđď¸ Weâre back with the fourth episode of Parkinson Weekly, hosted by Prof. Bas Bloem.This weekâs Article of the Week explores an exciting area of research:Bas explores the intriguing connection between proximity to golf courses and the risk of Parkinsonâs disease. Join us as we discuss the findings of the latest research article and what it could mean for understanding environmental factors linked to Parkinsonâs.đ You can read the full article here: https://pubmed.ncbi.nlm.nih.gov/40338549/Have a question youâd l...
2025-10-0208 minParkinson WeeklyBONUS Episode - Book: The Parkinson's Plan - New York Times Best Sellerđď¸ Weâre back with a BONUS episode of Parkinson Weekly, hosted by Prof. Bas Bloem.Weâre thrilled to bring you a very special bonus episode featuring The Parkinsonâs Plan, recently recognised as a New York Times Best Seller! đâ¨In this episode, we dive into the insights and strategies from the book that are helping people with Parkinsonâs take control of their health, lifestyle, and daily routines. Whether youâre living with Parkinsonâs, supporting someone who is, or simply passionate about neurological health, this episode is packed with...
2025-09-2507 minParkinson WeeklyEP 3 - Article Of The Week: Episode 3: Exenatide once a week versus placebo as a potential disease modifying treatment for people with Parkinsons disease in the UK: a phase 2, multi centre, double-blind, parallel-group, randomised, placebo-controlled triađď¸ Weâre back with the third episode of Parkinson Weekly, hosted by Prof. Bas Bloem.This weekâs Article of the Week explores an exciting area of research:âExenatide once a week versus placebo as a potential disease-modifying treatment for people with Parkinsonâs disease in the UK: a phase 2, multi-centre, double-blind, parallel-group, randomised, placebo-controlled trial.âđ You can read the full article here: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02808-3/fulltext & https://pubmed.ncbi.nlm.nih.gov/39919773/Have a question youâd like Bas to...
2025-09-1810 minParkinson WeeklyEP 2 - Article Of The Week: Stability and Accuracy of a diagnosis of Parkinson disease over 10 yearsWeâre back with another episode of Parkinson Weekly with Prof. Bas Bloem.In this edition, our Article of the Week is: âStability and Accuracy of a Diagnosis of Parkinson Disease Over 10 YearsâThis important study explores how accurate and stable a Parkinsonâs disease diagnosis remains across a decade, offering valuable insights for clinicians, researchers, and people living with Parkinsonâs.đ You can read the full article here: https://pubmed.ncbi.nlm.nih.gov/40184591/
2025-09-1109 minParkinson WeeklyEP 1 - Article Of The Week: Discontinuation or acute unplanned cessation of oral dopaminergic medications in persons with Parkinsonâs Disease: A Practice ReviewWelcome to the very first episode of Parkinson Weekly! Each week, Professor Bas Bloem, Neurologist at Radboud University Medical Center in Nijmegen, highlights his chosen Article of the Week and shares insights into what it means for people living with Parkinsonâs, their families, and healthcare professionals.In this inaugural episode, Bas discusses the article: âDiscontinuation or acute unplanned cessation of oral dopaminergic medications in persons with Parkinsonâs Disease: A Practice Review.â You can read the full article here: https://journals.sagepub.com/doi/10.1177/1877718X251356896Have a question...
2025-09-0409 minParkinson WeeklyPodcast PromoParkinson Weekly with Prof. Bas Bloem brings you his âarticle of the weekâ, alongside insights on every aspect of Parkinsonâs disease â for doctors, caregivers, patients, and beyond. A must-listen for anyone touched by Parkinsonâs.
2025-08-2801 minParkinson WeeklyEP 1 - Article Of The Week: Discontinuation or acute unplanned cessation of oral dopaminergic medications in persons with Parkinsonâs Disease: A Practice ReviewWelcome to the very first episode of Parkinson Weekly! Each week, Professor Bas Bloem, Neurologist at Radboud University Medical Center in Nijmegen, highlights his chosen Article of the Week and shares insights into what it means for people living with Parkinsonâs, their families, and healthcare professionals.In this inaugural episode, Bas discusses the article: âDiscontinuation or acute unplanned cessation of oral dopaminergic medications in persons with Parkinsonâs Disease: A Practice Review.â You can read the full article here: https://journals.sagepub.com/doi/10.1177/1877718X251356896Have a question youâd like...
2025-08-2809 min
Reflections on Parkinson's DiseaseSpecial Edition Episode: Navigating the PD Universe â Live from the BIAL PD Summit 2025 in Lisbon with Guest Speaker Sir Nicholas MostynJoin us for an exclusive live-recorded episode of 'Navigating the PD Universe' podcast, kicking off our new series at the BIAL PD Summit in Lisbon, 2025. Professors Werner Poewe and Bas Bloem welcome a remarkable special guest, Sir Nicholas Mostyn, host of the acclaimed Movers and Shakers podcast. Together, they dive into the challenges and realities of Parkinsonâs disease, blending expert insights with Sir Nicholasâs personal journey of living with the condition. This candid, inspiring conversation is a must-listen for anyone touched by Parkinsonâs.
2025-04-011h 01
Reflections on Parkinson's DiseaseS2 EP7: ABC of PD - The Letter N (Part 2): Non Motor Symptoms - ApomorphineFollowing on from the previous episode, our hosts delve deeper into the letter N, focusing on Non Motor Symptoms with a special emphasis on Apomorphine.
2022-12-1214 minReflections on Parkinson's DiseaseS2 EP6: ABC of PD - The Letter N: Non Motor SymptomsOur hosts discuss the Letter N in this episode, focusing predominantly on Non Motor Symptoms. This is a two part episode for the letter N and we are delighted to share this on World Movement Disorders Day 2022.
2022-11-2813 minReflections on Parkinson's DiseaseS2 EP5: ABC of PD - The Letter O: ON/OFF, On Demand Therapies, OpicaponeThe letter O is the focus of our Professors' attention in this episode. They discuss the concept of ON/OFF, On Demand Therapies, and the importance of Opicapone.
2022-11-1514 minReflections on Parkinson's DiseaseS2 EP4: ABC of PD - The Letter G: GBA and GeneticsIn this episode, Professor Werner Poewe and Bas Bloem discuss the letter G, with a particular focus on GBA and Genetics.
2022-11-0213 minReflections on Parkinson's DiseaseS2 EP3: ABC of PD - The Letter F: Fluctuations & FatigueIn Season 2, Episode 3, our Professors investigate the letter F, focusing on Fluctuations and Fatigue.
2022-09-3013 minReflections on Parkinson's DiseaseS2 EP2: ABC of PD - The Letter E: Early Morning Off, Evidence, Exercise, Early PDIn this latest episode of the S2: ABC of Parkinson's Disease, both Prof. look into the letter E where they discuss Early Morning Off, Evidence, Exercise, Early PD.
2022-07-2012 minReflections on Parkinson's DiseaseS2 EP1: ABC of PD - The Letter C: COMT Inhibitors, Continuous Dopaminergic DeliveryIn this new season, Prof. Poewe and Prof. Bloem will be discussing the ABC of Parkinsonâs Disease - each episode will have a certain letter attributed to the many different avenues within PD. The letter for this episode is C: COMT Inhibitors, Continuous Dopaminergic Delivery.
2022-07-2010 minReflections on Parkinson's DiseaseS1 EP7: Apomorphine and non-motor symptomsIn this episode of Reflections On Parkinson's Disease, both professors dive into the history of Apomorphine, the role of the drug within each of their hospitals/for their patients and how the drug impacts non-motor symptoms.Â
2021-12-1715 minReflections on Parkinson's DiseaseS1 EP6: Talking PD - Issues in doctor-patient communicationIn episode 6, both Profâs address the different experiences that they have encountered with their patients during their many years as PD specialists. They discuss ways in which Drâs communicate with patients on how medication problems may lead to fluctuating responses, what mechanisms can lead to changes in symptom severity and what their take is on the value of aids for communication i.e., wearing off questionnaires, home diaries and other techniques.
2021-08-1915 minReflections on Parkinson's DiseaseS1 EP5: The hardships of being offIn this latest Episode of Reflections on Parkinsonâs Disease, Profâs Bloem and Poewe discuss what is meant by âon/offâ fluctuations and what it entails. They evaluate the âgood on and the bad onâ and consider that when a patient is turned âonâ, medication can sometimes overshoot its target, which means patients develop involuntary movements which are called Dyskinesiaâs. The Profâs then explore the different types of Dyskenisiaâs, what problems can arise for patients who are suffering them and also how it can affect their loved ones in everyday life.
2021-07-1513 minReflections on Parkinson's DiseaseS1 EP4: Response Fluctuations in Parkinsonâs Disease - Why they can be missedIn the anticipation of Euro 2020, both Professorâs share their thoughts on who they will be supporting at this years tournament, before delving into the topic of Response Fluctuations in Parkinsonâs Disease and why they can be missed. They discuss how a patients education on the disease is vital to explain what response fluctuations are, the current ways in which patients are recording their experiences and finally whether the use of technology sensors could help patients detect their response fluctuations.
2021-06-1015 minReflections on Parkinson's DiseaseS1 EP3:Why do patients start to fluctuate?In Episode 3, Profs. Poewe and Bloem discuss why Parkinsons Disease patients develop fluctuations, how they can be treated & what mechanisms effect this. They also explore the practical elements of combining treatments and whether there are wiser ways of starting treatment.
2021-05-2119 minReflections on Parkinson's DiseaseS1 EP2: Motor Fluctuations and the levodopa long-duration responseIn this episode, Bas and Werner delve into the term âmotor fluctuationsâ which is linked to the long-term experience patients have with Levodopa. They discuss a study by George Cotzias regarding the âintermittency in the action of the drugâ, what the term âwearing offâ stands for and the differences between a short-duration/long-duration response.Â
2021-04-2916 minReflections on Parkinson's DiseaseS1 EP1:Levodopa Facts and MythsIn this episode both Professors dispel the myths and misconceptions of a drug that's been used for over 50 years. They discuss the idea of a "honeymoon period" for those using Levodopa and Prof. Bloem also reveals some interesting results from a study he carried out as well as addressing how Levodopa responds to tremors.Special thanks to BIAL for sponsoring this podcast.BIAL is an innovative pharmaceutical company. Dedicated to discovering, developing and commercializing medicines, we are committed to improve people's lives worldwide. Keeping life in mind.
2021-04-0715 minReflections on Parkinson's DiseaseA message from Prof Werner Poewe on the Reflections on Parkinson's upcoming Podcast seriesWelcome to the Reflections on Parkinsonâs podcast, brought to you by Oruen. In this cutting edge podcast we talk around the exciting topics in Parkinsonâs disease with 2 of the leading experts...Prof Bas Bloem and Prof Werner Poewe.Â
2021-04-0601 minReflections on Parkinson's DiseaseA message from Prof Bas Bloem on the Reflections on Parkinson's upcoming Podcast seriesWelcome to the Reflections on Parkinsonâs podcast, brought to you by Oruen. In this cutting edge podcast we talk around the exciting topics in Parkinsonâs disease with 2 of the leading experts...Prof Bas Bloem and Prof Werner Poewe.Â
2021-03-2501 min
Open SourceOruen - L'omnivague (Open Source Edit)Stream on Spotify
⼠https://open.spotify.com/track/6YKQ3UNAzjKvhKTvE1qu2U
Official Page
⼠https://www.DJopensource.com
Open Source Music on Spotify
⼠https://open.spotify.com/artist/2gponzmhHF1GO3L7J4Ox9B
Read Angelo's book "Music Talks: Turn Your Hobby Into A Profession"
⼠https://www.amazon.com/Music-Talks-Turn-Hobby-Profession-ebook/dp/B08H85L15V/
Download Psytrance FL studio Projects (*.flp)
⼠https://www.patreon.com/djopensource
Spotify Playlists (Add Your Track)
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Check Angelo's Orchestrations & Latest Productions
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Psycomics Series
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2020-08-3003 min
Open SourceOruen - Diable Gris (Open Source Edit)Listen on Spotify
⼠https://open.spotify.com/track/1rdeay0JOP6q6KkvOFKlLP
Official Page
⼠https://www.DJopensource.com
Open Source Music on Spotify
⼠https://open.spotify.com/artist/2gponzmhHF1GO3L7J4Ox9B
Read Angelo's book "Music Talks: Turn Your Hobby Into A Profession"
⼠https://www.amazon.com/Music-Talks-Turn-Hobby-Profession-ebook/dp/B08H85L15V/
Download Psytrance FL studio Projects (*.flp)
⼠https://www.patreon.com/djopensource
Spotify Playlists (Add Your Track)
⼠https://open.spotify.com/user/ii93onz33z7rrj08uu0dculjz
Check Angelo's Orchestrations & Latest Productions
⼠https://www.youtube.com/angelosmavros
Psycomics Series
⼠https://www.pinterest.com/djopensource/psycomics/
2020-07-2003 min