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Showing episodes and shows of
Peter Turnbaugh
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DMPK Insights
DMPK Insights #11: Drug Meets Bug: How the Gut Microbiome Shapes DMPK
For a captioned version or to access the transcript, please visit https://www.pharmaron.com/knowledge-center/dmpk-podcast-11-gut-microbiome/.In this podcast, Chris Bode (Pharmaron US Labs) interviews Peter Turnbaugh, a microbiologist and Professor of Microbiology and Immunology at the University of California San Francisco. Over the past 15-20 years, Peter has produced so much groundbreaking research in the endlessly fascinating field of the gut microbiome. His work is not limited to DMPK by any means, but in this episode, we discuss drug metabolism by gut bacteria and its impact on pharmacokinetics. Clinically, reduced efficacy and/or increased...
2025-03-18
47 min
Mind & Matter
Gut Microbiome Plasticity | Peter Turnbaugh | 214
Send us a textShort Summary: How diet shapes the gut microbiome and impacts health, with microbiologist Dr. Peter Turnbaugh breaking down the complex science.About the guest: Peter Turnbaugh, PhD is a professor of microbiology and immunology at the University of California, San Francisco, where he leads a lab studying the gut microbiome’s role in nutrition and drug response.Note: Podcast episodes are fully available to paid subscribers on the M&M Substack and everyone on YouTube. Partial versions are available elsewhere. Full transcript and ot...
2025-03-14
41 min
Mind & Matter
Gut Microbiome Plasticity | Peter Turnbaugh | 214
Short Summary: How diet shapes the gut microbiome and impacts health, with microbiologist Dr. Peter Turnbaugh breaking down the complex science.About the guest: Peter Turnbaugh, PhD is a professor of microbiology and immunology at the University of California, San Francisco, where he leads a lab studying the gut microbiome’s role in nutrition and drug response.Note: Podcast episodes are fully available to paid subscribers on the M&M Substack and everyone on YouTube. Partial versions are available elsewhere. Full transcript and other information on Substack.Episode Summary: Nick Jikomes talks to Pe...
2025-03-11
1h 21
バイオステーションポッドキャスト Bio-station Podcast
#15 Editing lives: Crafting Health and Future (ゲスト:小野隆一さん/UC Berkeley博士課程)
UC BerkeleyのComparative Biochemistryで博士課程をはじめられた小野隆一さんをゲストにお呼びして、海外博士課程事情から最新のCRISPRや腸内細菌叢ゲノム編集などについてお話ししました。さらに豪華共同ホストとしてペンシルバニア大学博士課程の山田さんにご参加いただきました。(収録日2024.10.20) Shownote: 小野さんX(Twitter) 程久美子先生ラボ 程先生のmiRNA解説記事(2024.10.31まで無料公開) Brady Cress先生ラボHP Bredy先生のNature Microbiology論文 Bredy先生ラボの最近の論文 SVAP Peter J. Turnbaugh先生ラボHP XPLANE Sam Sternberg先生の講義動画 CASTを見つけたPNAS論文 Defence island Anti-defence island(の例) Eugene V. Koonin先生ラボHP Jillian(Jill) Banfield先生ラボHP BORGの論文 Jennifer Doudna先生ラボHP Cas13の祖先の論文 Doudna研からのデリバリーの論文 Open CRISPR
2024-10-25
1h 00
Science is Fun!
How genes get turned off
Today I'm joined by another floor-mate of mine at UCSF, Bassem Al-Sady. Bassem's lab does beautiful and elegant work on how genes are silenced in cells ranging from yeast to stem cells. He explains all the mysteries that remain about this fundamental process and that aspects of it date back to the earliest types of cells. We also talk about his innovative teaching efforts and how to improve graduate education.
2024-03-17
1h 46
Science is Fun!
What boxing teaches us about autoimmunity
This week I'm so thrilled to interview Dr. Stephen Hauser, author of "The Face Laughs While the Brain Cries." He discusses a remarkable career as a physician-scientist, in which he uncovered a key role for B cells in the debilitating autoimmune disease multiple sclerosis. More remarkably, his perseverance led to the transformative drugs that are now available for this disease, emphasizing the importance of basic science for addressing long-standing healthcare challenges and the unique lens that practicing physicians can bring to biomedical research.
2024-03-03
1h 37
Science is Fun!
Can we eat saturated fat again?
This week I'm so thrilled to interview Dr. Ron Krauss. Ron has make seminal contributions to our understanding of heart disease, including early work on cholesterol and his ongoing studies of statins. He explains why human nutrition is so hard and what is needed to provide more predictive dietary guidelines.
2024-02-18
1h 47
Science is Fun!
Synbio meets immunotherapy
Synthetic biologist Kole Roybal joins us today. Kole is a leader in the emerging area of cell therapy, and has developed sophisticated ways of controlling immune cells for the treatment of cancer. He explains what led to these very recent breakthroughs and what he's excited about next.
2024-02-04
1h 40
Science is Fun!
Finding the AIDS virus
This week I'm joined by Jay Levy, a world expert in HIV. Jay was one of the first people to isolate the virus and had made numerous contributions to our understanding of HIV and AIDS. He walks us through this fascinating history and the current challenges in this area.
2024-01-21
1h 07
Science is Fun!
Natural born killers
I'm thrilled to interview Lewis Lanier this week, who recently stepped down as my department chair. Lewis has had a remarkable career in science and industry, including the early days of flow cytometry and the discovery of a new type of immune cell dubbed the "natural killer cell". He explains how these NK cells were found and why they're so unique and fascinating.
2024-01-07
1h 24
Science is Fun!
Placentas are amazing
This week my guest is Dr. Susan Fisher, a world renowned expert in the placenta. She explains how truly remarkable the placenta is and how it overturns a lot of what we normally assume about the body.
2023-12-17
1h 07
Science is Fun!
The bacterial cell whisperer
I'm am so excited to welcome Dr. Shaeri Mukherjee to the show. Shaeri is my next-door neighbor at UCSF and has been dubbed the "bacteria whisperer". Her lab uses bacteria as tools to uncover fundamental insights into cell biology.
2023-12-03
1h 21
Axial Podcast
How Our Microbiomes affect Nutrition & Pharmacology with Peter Turnbaugh
Peter Turnbaugh is a professor at UCSF studying the human microbiome’s effect on pharmacology and nutrition. In our conversation, we discuss his journey to become a scientist and help pioneer the microbiome field starting in graduate school. We talk about his research as a fellow at Harvard then professor at UCSF, and his lab’s current work. A key theme across the conversation is learning by doing.Peter’s work has been anchored around predicting and controlling the metabolism of complex microbial communities. Going to a liberal arts college, Whitman College, Peter gravitated more to science because the gr...
2023-07-06
1h 02
Science is Fun!
Filming a movie using CRISPR technology
We’re back this week with Seth Shipman from the Gladstone Institutes and the University of California, San Francisco. Seth has built molecular recording devices that can record data within living cells. He even used these methods to re-create one of the first movies put to film. This work has clear technological implications and is also providing insights into phage biology.
2023-02-10
1h 31
Science is Fun!
Who needs a biochemist when you have tiny beads?
We’re back this week with Polly Fordyce. Polly is an Assistant Professor of Genetics and Bioengineering at Stanford. She has built remarkable tools for studying transcription factors and enzymes, really accelerating what is possible and opening up new areas of study. She explains why hydrogels are so cool and how you too can use them in your research program.
2023-01-27
1h 53
Science is Fun!
Fruit flies love the metaverse
Science is Fun is finally back after a long hiatus. Where have we been? I’ve been doing science now that the pandemic slow-down has lifted. So much science to do, so little time! I’ve got an exciting line-up for the next few weeks - a mini-season of shows. I hope you enjoy it and stay subscribed to the show for when our next full season launches. This week I welcome Dr. Yvette Fisher to the show. Yvette is a neuroscientist at the University of California, Berkeley. She does wild experiments, including putting fruit flies into virtual reality simu...
2023-01-13
1h 49
Osher WISE: Well-being and Integrative Science for Everyone (Audio)
They Are What You Eat - How Food and Drugs Interact with the Gut Microbiome
Our bodies are dynamic ecosystems housing trillions of microbes that, while invisible to the naked eye, play a critical role in shaping human health. Scientists are beginning to understand the superpowers the microbiome holds. In this program, Peter Turnbaugh, Ph.D., discusses how our gut microbes are the result of the food we eat, which in turn impacts our health. Series: "Osher WISE: Well-being and Integrative Science for Everyone" [Health and Medicine] [Show ID: 38131]
2022-07-16
1h 28
Microbiome (Audio)
They Are What You Eat - How Food and Drugs Interact with the Gut Microbiome
Our bodies are dynamic ecosystems housing trillions of microbes that, while invisible to the naked eye, play a critical role in shaping human health. Scientists are beginning to understand the superpowers the microbiome holds. In this program, Peter Turnbaugh, Ph.D., discusses how our gut microbes are the result of the food we eat, which in turn impacts our health. Series: "Osher WISE: Well-being and Integrative Science for Everyone" [Health and Medicine] [Show ID: 38131]
2022-07-16
1h 28
Microbiome (Video)
They Are What You Eat - How Food and Drugs Interact with the Gut Microbiome
Our bodies are dynamic ecosystems housing trillions of microbes that, while invisible to the naked eye, play a critical role in shaping human health. Scientists are beginning to understand the superpowers the microbiome holds. In this program, Peter Turnbaugh, Ph.D., discusses how our gut microbes are the result of the food we eat, which in turn impacts our health. Series: "Osher WISE: Well-being and Integrative Science for Everyone" [Health and Medicine] [Show ID: 38131]
2022-07-16
1h 28
UC San Francisco (Audio)
They Are What You Eat - How Food and Drugs Interact with the Gut Microbiome
Our bodies are dynamic ecosystems housing trillions of microbes that, while invisible to the naked eye, play a critical role in shaping human health. Scientists are beginning to understand the superpowers the microbiome holds. In this program, Peter Turnbaugh, Ph.D., discusses how our gut microbes are the result of the food we eat, which in turn impacts our health. Series: "Osher WISE: Well-being and Integrative Science for Everyone" [Health and Medicine] [Show ID: 38131]
2022-07-16
1h 28
Osher WISE: Well-being and Integrative Science for Everyone (Video)
They Are What You Eat - How Food and Drugs Interact with the Gut Microbiome
Our bodies are dynamic ecosystems housing trillions of microbes that, while invisible to the naked eye, play a critical role in shaping human health. Scientists are beginning to understand the superpowers the microbiome holds. In this program, Peter Turnbaugh, Ph.D., discusses how our gut microbes are the result of the food we eat, which in turn impacts our health. Series: "Osher WISE: Well-being and Integrative Science for Everyone" [Health and Medicine] [Show ID: 38131]
2022-07-16
1h 28
UC San Francisco (Video)
They Are What You Eat - How Food and Drugs Interact with the Gut Microbiome
Our bodies are dynamic ecosystems housing trillions of microbes that, while invisible to the naked eye, play a critical role in shaping human health. Scientists are beginning to understand the superpowers the microbiome holds. In this program, Peter Turnbaugh, Ph.D., discusses how our gut microbes are the result of the food we eat, which in turn impacts our health. Series: "Osher WISE: Well-being and Integrative Science for Everyone" [Health and Medicine] [Show ID: 38131]
2022-07-16
1h 28
Science is Fun!
Don't Panic! How to live with COVID-19
I'm am so excited to welcome Dr. Monica Gandhi to the show. Throughout the pandemic, Monica has been a source of reliable and clear headed insight, especially with regards to the importance of re-opening schools. This conversation remains timely given the increasing rate of infections and stalled vaccination effort.
2021-09-26
1h 53
Science is Fun!
How to design a drug in an afternoon
This week I chat with another talented chemist: Bill DeGrado from UCSF. Bill is a pioneer in the de novo design of proteins. He talks about how he got into this area and how it has created opportunities to treat disease.
2021-08-22
1h 30
Science is Fun!
Enzyme spotting
This week I'm joined by Charly Craik, a chemist at UCSF who develops sophisticated tools for studying biology. He talks about his quest to watch enzymes function in real-time in cells and even whole mice, and how his research is paving the way for new therapies for HIV, cancer, and COVID-19.
2021-08-15
1h 54
Science is Fun!
Should scientists be politicians?
Keith Yamamoto, the Vice Chancellor for Science Policy and Strategy at UCSF, explains why he has been committed throughout his career to reform the funding, publication, and practice of science. He also discusses his vision for the future of precision medicine and how team-based projects could accelerate scientific progress.
2021-05-23
1h 44
Science is Fun!
Do we already know the cure for cancer?
Dr. Alan Venook is a renowned expert on gastrointestinal malignancies at UCSF. He discusses the innovative ways doctors are treating cancer, the challenges of designing clinical trials, and the future of cancer therapy.
2021-05-09
1h 42
Science is Fun!
Should biologists spend less time doing experiments?
KC Huang, a physicist at Stanford with one of the most eclectic research histories I've seen, patiently explains photons, the biophysics of cell shape, and why biologists should embrace theory.
2021-05-02
2h 01
Science is Fun!
What is curiosity-driven science?
Dr. Hiten Madhani is an expert in yeast biology, including the neglected human fungal pathogen Cryptococcus neoformans. Hiten's lab has made major contributions to our understanding of gene splicing, gene silencing, and quorum sensing. These eclectic areas arise organically from his group's ability to follow the data and their own curiosity, coupled to his strategy of encouraging trainees to follow their passion.
2021-04-25
2h 00
Science is Fun!
What is a nuclear lamina and why should you care?
Dr. Abby Buchwalter, my former classmate from Washington University in Saint Louis, tells us why everyone should care about the nuclear lamina. She also talks about the winding path of discovery and her efforts to found the SciChats outreach program at the Salk Institute.
2021-04-18
1h 50
Science is Fun!
Can ticks teach us how to make better hand sanitizer?
My guest this week is Dr. Seemay Chou, my colleague at UCSF who uses ticks as a model system for host-microbial interactions. She talks about her remarkable discovery of bacteria genes that have transferred into ticks and how they serve to protect ticks from microbes found on human skin.
2021-04-11
2h 00
Science is Fun!
Can dieting help you live forever?
My guest this week is Dr. Emily Goldberg, a brand new faculty member at UCSF. She talks about growing up with academic parents and how she got into the rapidly growing field of immunometabolism, as well as the complex role of ketogenic diets and caloric restriction is shaping aging and susceptibility to infection.
2021-04-04
1h 48
Science is Fun!
Do microbes control our immune system?
My guest this week is Dr. Sarkis Mazmanian, a Professor at Cal Tech, and certified Genius by the MacArthur Foundation. Sarkis talks about how he got into microbiome research and his remarkable contributions to infectious disease, immunology, and neurology.
2021-03-28
1h 48
Science is Fun!
Why can't you understand what your Doctor is talking about?
My first international guest, the renowned Irish microbiome researcher Fergus Shanahan, talks about his new book "The Language of Illness" and his eclectic research on the inflammatory bowel diseases (plural!), physical fitness (not exercise!), and Irish Travelers (popularized by the movie Snatch).
2021-03-21
2h 21
Science is Fun!
Can the cheese in your fridge get you a PhD?
My guest this week is Dr. Rachel Dutton from UCSD who is recognized in both scientific and culinary circles for her ingenious use of cheese rinds as a model system to study microbial ecology. Learn more about what inspired her to take up this line of research and what they have learned so far.
2021-02-21
1h 37
Science is Fun!
Why COVID-19 isn’t the end of our fight against infectious disease
My guest this week is Dr. Gerry Wright, a Professor at McMaster who is renowned for his efforts to understand and combat antibiotic resistance in pathogenic microbes. This interview is especially timely given the ongoing pandemic and the need to invest more heavily in infectious disease research.
2021-02-07
1h 46
Science is Fun!
How to start a lab during a pandemic
My guest this week is Dr. Aspen Reese, a new faculty at the University of California, San Diego. Aspen talks about the unique challenges of starting a lab during a pandemic and shares how her background in ecology and evolution has provided a unique lens to understand the human microbiome.
2021-01-17
1h 49
Science is Fun!
How to make drugs safer and combat aging
My guest this week is Dr. Garret Fitzgerald, the Director of the Institute for Translational Medicine and Therapeutics at the University of Pennsylvania. We discuss his current work at Calico, a Google backed company that aims to combat aging, including Garret's fascination with circadian rhythms. He also explains his key role in revealing the dangerous side effects of selective inhibitors of COX-2, leading to removing Vioxx from the market in 2004 and a black box warning on its competitor Celebrex.
2021-01-10
1h 51
Science is Fun!
Why volcanos matter for tracing outbreaks
My guest this week is Dr. Martin Blaser. I know Marty well due to his more recent work on antibiotics and their off-target impacts on the gut microbiome, described in his book "Missing Microbes". We discuss the origins of this work during his time tracking epidemics at the CDC, his love for the rare but fascinating Campylobacter fetus, and his seminal work on identifying a "symbiosis factor" for Helicobacter pylori.
2021-01-03
1h 52
Science is Fun!
Is the microbiome a viable drug target?
My guest this week is Dr. Matt Redinbo from the University of North Carolina at Chapel Hill. Matt has had a remarkable career in both academia and industry. He discusses the challenges of translating basic research and the importance of doing the killer experiment as soon as possible. We talk about his evolution from focusing solely on human enzymes for drug metabolism to studying microbes, and the vast potential for the microbiome as a novel drug target.
2020-12-20
1h 51
Science is Fun!
Why is dieting so hard?
This week I'm joined by my friend and collaborator Dr. Suneil Koliwad, the Chief of the Division of Endocrinology and Metabolism at UCSF. Suneil discusses how the pandemic has changed medicine, the perplexing differences between ethnic groups in metabolic disease, and his research on the complex links between diet, inflammation, and obesity.
2020-12-13
1h 58
Science is Fun!
Will studying snakes help stop the next pandemic?
My guest this week is Dr. Joe DeRisi, a pioneer in functional genomics and leader of a collaborative effort to accelerate SARS-CoV-2 testing and discovery. Joe is the co-President of the Chan Zuckerberg Biohub and has had a remarkable series of technological breakthroughs throughout his career, including the invention of DNA microarrays. He talks about applying these approaches to diagnose mysterious diseases in humans and pets as well as his current focus on COVID-19.
2020-12-06
1h 38
Science is Fun!
What epidemiology teaches us about salt, sugar, and COVID-19
My guest this week is Dr. Kristin Bibbins-Domingo. Her pioneering studies have used computational simulations to predict the public health implications of changes to diet, including a focus on salt and sugar intake. We discuss how she got into nutrition and some of the controversies around what we should and should not eat. We also discuss her current efforts to address inequalities in the risk of SARS-CoV-2 infection and recovery.
2020-11-22
1h 56
Science is Fun!
Can microbes save us from global warming?
My guest this week is Dr. Adam Arkin, our first interview outside of UCSF! Adam works across the Bay at Lawrence Berkeley National Labs and is a leader in the emerging fields of systems and synthetic biology. He has published more than 300 papers on a wide range of subjects and tells us about some of the large-scale initiatives he is currently leading and his fascination with viruses and bacteria.
2020-11-15
2h 00
Science is Fun!
Is CRISPR the cure for everything?
My guest this week is immunologist Dr. Alex Marson. Alex talks about his recent work on SARS-CoV-2, his efforts to translate CRISPR technology to treat patients, and his long-standing collaboration with the Dr. Jennifer Doudna, recipient of the 2020 Nobel Prize in Chemistry. We also discuss how he’s managed to accumulate so many titles at such an early stage in his career: Scientific Director for Biomedicine at the Innovative Genomics Institute and Founding Director of the Gladstone Institute for Genomic Immunology.
2020-11-08
1h 32
Science is Fun!
Can silver help your body heal after surgery?
My guest this week is Dr. Hobart Harris, who was the Chief of General Surgery at UCSF for 18 years. Hobart talks about the challenges and innovations happening in the surgery field and his research on developing strategies to accelerate the healing process following a surgery. We also talk in-depth about the Black Lives Matter movement and challenges around race and equality in science and medicine.
2020-11-01
2h 17
Science is Fun!
Is diversity the key to precision medicine?
My guest this week is Esteban Burchard an expert in pharmacogenetics and asthma. Esteban’s prolific scientific contributions have been featured on Science Friday and other shows. He also served on President Obama’s Precision Medicine Initiative. I was particularly excited to discuss issues of Diversity, Equity, and Inclusion with him, as he is a leader in emphasizing the importance of studying drug response across diverse individuals.
2020-10-25
1h 15
Science is Fun!
Are all viruses the same?
Last July I had the pleasure of talking with Dr. Melanie Ott, the Director of the Gladstone Institute of Virology in San Francisco. While I would have been thrilled to talk to her under any circumstance, the ongoing SARS-CoV-2 pandemic has made one-on-one time with a virologist more valuable than ever. In addition to catching up on the latest news about COVID-19, we discussed her long-standing interest in HIV and the surprising similarities between unrelated viruses.
2020-10-18
1h 37
Science is Fun!
Why the lysosome is the #1 organelle
Last March, as the pandemic was picking up steam, I had the pleasure to interview a friend and colleague Dr. Rushika Perera, a rising star and Assistant Professor at UCSF. Before our conversation, I had heard about the lysosome but just had some vague notion that it is similar to recycling, an essential service for sure but not one I want to think about everyday. By the end of our interview, I was almost ready to scrap the microbiome and devote my life to becoming a lysosome-ologist. She’s just that convincing and passionate, having clearly found an ideal niche wi...
2020-10-11
1h 21
Science is Fun!
Why microbes on your skin are good for you
My guest this week is Tiffany Scharschmidt, a close colleague of mine in the UCSF Benioff Center for Microbiome Medicine. I really admire how well-spoken she is and how carefully considered her research and other scholarly work is, a stark contrast to my own “fire, ready, aim” approach. Another remarkable fact about Tiffany is that she never got a Ph.D. Instead, she transitioned directly from an M.D. to a translational research program that spans deep molecular mechanism to clinical studies. Hear why and how she made that switch, whether or not microbes may someday cure skin disease, and what...
2020-10-04
1h 36
Science is Fun!
Immunology does everything, it even cures cancer!
My guest this week is Max Krummel, whose career has been truly remarkable. As a graduate student, he generated antibodies to CTLA-4, which not only helped to identify an inhibitory pathway of T cell regulation but can also be used to block that pathway. This work, which led the way to cancer immunotherapy, was featured in the recent documentary "Jim Allison: Breakthrough." To Max, these breakthroughs emphasized to him the importance of technology in driving innovation, a theme that runs through his use of fluorescent imaging, live-imaging, and immune-profiling as well as his leadership of the ImmunoX Initiative. Max...
2020-09-13
1h 40
Science is Fun!
Why GWAS aren't so bad after all
My guest this week is Lindsey Criswell, who was recently named the director of the National Institute of Arthritis and Musculoskeletal and Skin Diseases. Lindsey has deep experience in clinical rheumatology and human genetics. She talks about the intricacies of medical training and practice, then explains the history and importance of genome-wide association studies and how they set the stage for her current focus on epigenetics.
2020-09-06
1h 35
Science is Fun!
What is Warren G's favorite T cell?
Welcome back! After an easy start with Oren last July, I was able to catch a big fish - a world-renowned UCSF faculty member in our Diabetes Center, Jeff Bluestone. Jeff has made remarkable contributions to our understanding of T-cell activation, co-stimulation, and immune tolerance including >400 peer-reviewed publications. He shares his passion for collaborative science, including his leadership roles at UCSF, the Immune Tolerance Network, the Parker Institute for Cancer Immunotherapy, and more. Despite these "big science" projects, Jeff remains closely involved in his lab's research and is a committed mentor.
2020-08-23
1h 58
Science is Fun!
Microbes aren't so scary after all
Dr. Lynch is the Director of the UCSF Benioff Center for Microbiome Medicine and exemplifies the benefits of studying human biology at a range of scales, from “ecosystems to molecules.” Her translational research program has deepened our understanding of the role of the microbiome in allergy and asthma with a particular focus on the establishment of the microbiome early in life. Her team has identified microbes that could be administered to high-risk infants for prevention of childhood allergy and asthma, leading to a spin-off company. She talks about the importance of microbiology for understanding human biology and her path from...
2020-08-16
1h 38
Science is Fun!
Why art class can help you solve a protein structure
Oren, my friend and colleague at UCSF, got an MD and a PhD from Yale and has deep expertise in structural biology. This includes using all sorts of fancy techniques that I don’t understand: crystallography, electron microscopy, and small-angle x-ray scattering. After cutting his teeth on eukaryotes, he joined the dark side (microbiology) focusing on tuberculosis and other infectious diseases. His lab continues to push the field of structural biology forward into new and exciting areas, while also developing innovative new genetic techniques like a mobile CRISPR-Cas system that can be used to study diverse pathogenic and commensal ba...
2020-08-09
2h 06
Science is Fun!
A legend of cancer biology
My guest this week is Zena Werb, whose research has had a profound impact on our understanding of development, cancer, and the epithelial microenvironment. Her publication list is truly inspiring with >500 papers and counting, including multiple seminal manuscripts. Despite this rich history, I was struck by how deeply involved she still was in her active projects and her infectious passion for scientific discovery. Many senior faculty go the administrative route, spending more and more time leading large projects and campus initiatives. In contrast, Zena proves that it is possible to stay focused on the science and that there’s al...
2020-08-02
1h 57
Science is Fun!
COVID-19, video games, and immunity
Welcome to Science is Fun! I hope you enjoy our first ever episode. Episodes will drop weekly, possibly less frequently due to COVID-19 and my general lack of expertise. Visit www.scienceisfuncast.com for more information. My guest this week is Richard Locksley, who is a remarkable and quite accomplished immunologist who has made seminal contributions to our understanding of T cells, innate lymphoid cells, and Tuft cells. He is an investigator with HHMI, a full Professor at UCSF, and the Director of the Sandler Asthma Basic Research Center. Rich was actually one of the...
2020-07-24
1h 19
Physionic
The Microbiome degrades Parkinson's Medicine + FREE Nutrition Guide Announcement
In this episode, I discuss a cool study looking at the microbiome and its impact on L-dopa, an anti-Parkinson's treatment, as well as offer some details on an upcoming, free nutrition guide to walk you through how to make your own nutrition protocol for weight and fat loss. Reference: Vayu Maini Rekdal, Elizabeth N. Bess, Jordan E. Bisanz, Peter J. Turnbaugh, Emily P. Balskus. Discovery and inhibition of an interspecies gut bacterial pathway for Levodopa metabolism. Science, 2019; 364 (6445): eaau6323 DOI: 10.1126/science.aau6323 YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7...
2019-06-24
10 min
Public Health (Audio)
Eating for Two Trillion: Dietary Intake Shapes Our Resident Gut Microbes - 2015 COAST/SSEW Symposium - Gut Feelings: The Microbiome the Mind and Metabolic Health
Humans are each home to trillions of microbes that have a widespread impact on our physiology and predisposition to disease. Peter Turnbaugh, PhD, Assistant Professor, Department of Microbiology and Immunology, UCSF, explains. Series: "UCSF Consortium for Obesity Assessment, Study and Treatment" [Health and Medicine] [Science] [Education] [Professional Medical Education] [Show ID: 30503]
2016-02-24
48 min
Public Health (Video)
Eating for Two Trillion: Dietary Intake Shapes Our Resident Gut Microbes - 2015 COAST/SSEW Symposium - Gut Feelings: The Microbiome the Mind and Metabolic Health
Humans are each home to trillions of microbes that have a widespread impact on our physiology and predisposition to disease. Peter Turnbaugh, PhD, Assistant Professor, Department of Microbiology and Immunology, UCSF, explains. Series: "UCSF Consortium for Obesity Assessment, Study and Treatment" [Health and Medicine] [Science] [Education] [Professional Medical Education] [Show ID: 30503]
2016-02-24
48 min
Wellbeing (Video)
Eating for Two Trillion: Dietary Intake Shapes Our Resident Gut Microbes - 2015 COAST/SSEW Symposium - Gut Feelings: The Microbiome the Mind and Metabolic Health
Humans are each home to trillions of microbes that have a widespread impact on our physiology and predisposition to disease. Peter Turnbaugh, PhD, Assistant Professor, Department of Microbiology and Immunology, UCSF, explains. Series: "UCSF Consortium for Obesity Assessment, Study and Treatment" [Health and Medicine] [Science] [Education] [Professional Medical Education] [Show ID: 30503]
2016-02-24
48 min
Wellbeing (Audio)
Eating for Two Trillion: Dietary Intake Shapes Our Resident Gut Microbes - 2015 COAST/SSEW Symposium - Gut Feelings: The Microbiome the Mind and Metabolic Health
Humans are each home to trillions of microbes that have a widespread impact on our physiology and predisposition to disease. Peter Turnbaugh, PhD, Assistant Professor, Department of Microbiology and Immunology, UCSF, explains. Series: "UCSF Consortium for Obesity Assessment, Study and Treatment" [Health and Medicine] [Science] [Education] [Professional Medical Education] [Show ID: 30503]
2016-02-24
48 min
Obesity Research and Prevention (Audio)
Eating for Two Trillion: Dietary Intake Shapes Our Resident Gut Microbes - 2015 COAST/SSEW Symposium - Gut Feelings: The Microbiome the Mind and Metabolic Health
Humans are each home to trillions of microbes that have a widespread impact on our physiology and predisposition to disease. Peter Turnbaugh, PhD, Assistant Professor, Department of Microbiology and Immunology, UCSF, explains. Series: "UCSF Consortium for Obesity Assessment, Study and Treatment" [Health and Medicine] [Science] [Education] [Professional Medical Education] [Show ID: 30503]
2016-02-24
48 min
Obesity Research and Prevention (Video)
Eating for Two Trillion: Dietary Intake Shapes Our Resident Gut Microbes - 2015 COAST/SSEW Symposium - Gut Feelings: The Microbiome the Mind and Metabolic Health
Humans are each home to trillions of microbes that have a widespread impact on our physiology and predisposition to disease. Peter Turnbaugh, PhD, Assistant Professor, Department of Microbiology and Immunology, UCSF, explains. Series: "UCSF Consortium for Obesity Assessment, Study and Treatment" [Health and Medicine] [Science] [Education] [Professional Medical Education] [Show ID: 30503]
2016-02-24
48 min
COAST: UCSF Center for Obesity Assessment, Study and Treatment (Audio)
Eating for Two Trillion: Dietary Intake Shapes Our Resident Gut Microbes - 2015 COAST/SSEW Symposium - Gut Feelings: The Microbiome the Mind and Metabolic Health
Humans are each home to trillions of microbes that have a widespread impact on our physiology and predisposition to disease. Peter Turnbaugh, PhD, Assistant Professor, Department of Microbiology and Immunology, UCSF, explains. Series: "UCSF Consortium for Obesity Assessment, Study and Treatment" [Health and Medicine] [Science] [Education] [Professional Medical Education] [Show ID: 30503]
2016-02-24
48 min
COAST: UCSF Center for Obesity Assessment, Study and Treatment (Video)
Eating for Two Trillion: Dietary Intake Shapes Our Resident Gut Microbes - 2015 COAST/SSEW Symposium - Gut Feelings: The Microbiome the Mind and Metabolic Health
Humans are each home to trillions of microbes that have a widespread impact on our physiology and predisposition to disease. Peter Turnbaugh, PhD, Assistant Professor, Department of Microbiology and Immunology, UCSF, explains. Series: "UCSF Consortium for Obesity Assessment, Study and Treatment" [Health and Medicine] [Science] [Education] [Professional Medical Education] [Show ID: 30503]
2016-02-24
48 min
Meet the Microbiologist
MTS43 - Rob Knight - The Microbes That Inhabit Us
In this episode, I speak to Rob Knight, an assistant professor in the Department of Chemistry and Biochemistry at the University of Colorado, Boulder. Knight studies our inner ecology: the 100 trillion microbes that grow in and on our bodies. Knight explained how hundreds of species can coexist on the palm of your hand, how bacteria manipulate your immune system and maybe even your brain, and how obesity and other health problems may come down to the wrong balance of microbes. Links to studies mentioned in this episode: Ruth Ley and Peter Turnbaugh's studies on...
2010-02-03
52 min