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Auscast MedicalAuscast MedicalEpisode 82: Pharmacogenomics | Personalised medicinesThe interplay between genetics and medications is important but complex. Pharmacogenomic testing provides doctors with information about how individual patients may respond to certain medications (ie. fast and slow metabolisers). The RCPA recently released guidelines for doctors about requesting patient pharmacogenomic testing before prescribing some medications. These guidelines have identified 35 medications into three pharmacogenomics testing categories: recommend, consider, and no consensus. We discuss this testing with our guest today. This is the story of pharmacogenomics. RCPA guidelines: https://www.rcpa.edu.au/Library/Practising-Pathology/Pharmacogenomic-Indications-in-Australia Our special guest: Our s...2025-06-0246 minThis Medical LifeThis Medical LifeEpisode 82: Pharmacogenomics | Personalised medicinesThe interplay between genetics and medications is important but complex. Pharmacogenomic testing provides doctors with information about how individual patients may respond to certain medications (ie. fast and slow metabolisers). The RCPA recently released guidelines for doctors about requesting patient pharmacogenomic testing before prescribing some medications. These guidelines have identified 35 medications into three pharmacogenomics testing categories: recommend, consider, and no consensus. We discuss this testing with our guest today. This is the story of pharmacogenomics. RCPA guidelines: https://www.rcpa.edu.au/Library/Practising-Pathology/Pharmacogenomic-Indications-in-Australia Our special guest: Our s...2025-06-0246 minThis Medical LifeThis Medical LifeEpisode 81: Familial Adenomatous Polyposis (FAP)In 1924, a surgeon and a pathologist had a conversation about some patients with multiple bowel polyps. The pathologist, Dr Cuthbert Dukes, and the surgeon, Mr JP Lockhart-Mummery, noted that patients had a family history of bowel cancer and could have hundreds of colonic polyps. They, with the help of HRJ Bussey, set up the Polyposis Registry. The registry collected information about these patients and the families from 1918 to 1954. They found that patients developed polyps in childhood, the risk of affected children was 50%, and cancer took 15 years to develop from first diagnosis. This was clearly a familial disease.2025-05-121h 18Auscast MedicalAuscast MedicalEpisode 81: Familial Adenomatous Polyposis (FAP)In 1924, a surgeon and a pathologist had a conversation about some patients with multiple bowel polyps. The pathologist, Dr Cuthbert Dukes, and the surgeon, Mr JP Lockhart-Mummery, noted that patients had a family history of bowel cancer and could have hundreds of colonic polyps. They, with the help of HRJ Bussey, set up the Polyposis Registry. The registry collected information about these patients and the families from 1918 to 1954. They found that patients developed polyps in childhood, the risk of affected children was 50%, and cancer took 15 years to develop from first diagnosis. This was clearly a familial disease.2025-05-121h 18VJHemOnc PodcastVJHemOnc PodcastAddressing unmet needs in myeloma: early detection, frail/elderly patients, triple-class exposed disease, & more!In recognition of Myeloma Awareness Month 2025, this podcast explores key unmet needs and unanswered questions in myeloma research and patient care, offering insights and strategies for healthcare professionals to address them. The discussion centers on four topics: the treatment of smoldering myeloma, managing frail and elderly patients, challenges in triple-class refractory disease, and racial disparities in myeloma care. Featuring experts Karthik Ramasamy, MBBS, MRCP, FRCPath, PhD, Oxford University Hospitals NHS Foundation Trust, Oxford, UK, Tarek Mouhieddine, MD, Mount Sinai Medical Center, New York City, NY, Mateo Mejia Saldarriaga, MD, Weill Cornell Medicine, New York, NY, Mohamad Mohty, MD...2025-03-1427 minVJHemOnc PodcastVJHemOnc PodcastAddressing unmet needs in myeloma: early detection, frail/elderly patients, triple-class exposed disease, & more!In recognition of Myeloma Awareness Month 2025, this podcast explores key unmet needs and unanswered questions in myeloma research and patient care, offering insights and strategies for healthcare professionals to address them. The discussion centers on four topics: the treatment of smoldering myeloma, managing frail and elderly patients, challenges in triple-class refractory disease, and racial disparities in myeloma care. Featuring experts Karthik Ramasamy, MBBS, MRCP, FRCPath, PhD, Oxford University Hospitals NHS Foundation Trust, Oxford, UK, Tarek Mouhieddine, MD, Mount Sinai Medical Center, New York City, NY, Mateo Mejia Saldarriaga, MD, Weill Cornell Medicine, New York, NY, Mohamad Mohty, MD...2025-03-1427 minAmerican Railroading PodcastAmerican Railroading PodcastRail Resources – The Surface Transportation Board with Chairman Patrick FuchsWelcome to the American Railroading Podcast! In this episode our host Don Walsh is joined by guest Patrick Fuchs, Chairman of the Surface Transportation Board (STB). Together they discuss who the STB is, how and why the STB was created, and they do a deep dive into not only all the various functions of the STB, but also all the different ways in which the STB is a valuable resource to the rail industry. Tune in to this episode to gain valuable insights and broaden your understanding of American Railroading! You can find this episode and more on the...2025-02-271h 11Beyond DeathBeyond DeathFEBRUARY JOURNAL CLUB - The utility of postmortem radiological imaging in forensic neuropathology practiceWelcome to the February Journal Club!   This month, we present the following article: Iles L. The utility of postmortem radiological imaging in forensic neuropathology practice. Pathology. 2024 Nov 14:S0031-3025(24)00293-9. doi: 10.1016/j.pathol.2024.10.005. Epub ahead of print. PMID: 39668072. Available here: https://www.pathologyjournal.rcpa.edu.au/article/S0031-3025(24)00293-9/fulltext   The discussion focuses on the integration of PMCT in forensic neuropathology, highlighting its strengths in detecting medium-to-large hemorrhages, guiding examination planning, and its limitations in identifying smaller injuries or vascular conditions. Tune in to ex...2025-02-0111 minAuscast MedicalAuscast MedicalEpisode 70: Understanding Troponin | As Serious As A Heart AttackTroponin is a protein found in heart muscle that was a game changer when it came to diagnosing heart attacks and myocardial injury in the late 1990s. Three decades later, it is an invaluable test with widespread use throughout medicine. Troponin assays are venturing into their 5th generation with high-sensitivity and Point-Of-Care (POC) devices. However, there are important exceptions, caveats and pitfalls for doctors to know. This is the story of troponin. Our special guest: Our special guest is Dr Christina Trambas who is a chemical pathologist, Medical Director at St V...2024-10-1448 minThis Medical LifeThis Medical LifeEpisode 70: Understanding Troponin | As Serious As A Heart AttackTroponin is a protein found in heart muscle that was a game changer when it came to diagnosing heart attacks and myocardial injury in the late 1990s. Three decades later, it is an invaluable test with widespread use throughout medicine. Troponin assays are venturing into their 5th generation with high-sensitivity and Point-Of-Care (POC) devices. However, there are important exceptions, caveats and pitfalls for doctors to know. This is the story of troponin. Our special guest: Our special guest is Dr Christina Trambas who is a chemical pathologist, Medical Director at St V...2024-10-1448 minRCPA: The Pathologists CutRCPA: The Pathologists CutThe complementary role of radiology in pathology investigations in cases of perinatal lossIn this episode of our mini-series on perinatal pathology, RCPA President, Associate Professor Trishe Leong is joined by anatomical pathologist Dr Nick Manton and paediatric radiologist Dr Ajay Taranath who work together at The Women's and Children's Hospital, Adelaide. Together, Dr Manton and Dr Taranath shed light on the critical role of radiology in the perinatal autopsy process, highlighting the nuanced collaboration between radiologists and pathologists in unravelling the mysteries of perinatal deaths. 2024-04-2924 minPyrénées FM SportPyrénées FM SportPyrénées Fm Sport : Estelle Carretier, Présidente du Rugby Club Portes d’Ariège et Chloé Martins, Représentante de l’AmicaleEstelle Carretier, Présidente du Rugby Club Portes d’Ariège et Chloé Martins, Représentante de l’Amicale, partagent leur passion pour le rugby féminin dans la basse Ariège. Elles révèlent les motivations derrière la création du club à La Tour-du-Crieu et le rôle crucial de l'Amicale dans son développement. Ensemble, elles dévoilent les objectifs du RCPA pour les équipes cadettes et seniors, ainsi que leur vision pour promouvoir le rugby féminin dans la région. Elles discutent des défis rencontrés lors de la création du club et de l'importance...2024-04-2606 minRCPA: The Pathologists CutRCPA: The Pathologists CutS3 E3 Redesign of the Victorian Perinatal Autopsy ServiceIn this episode of our mini-series on perinatal pathology, RCPA President, Associate Professor Trishe Leong is joined by anatomical pathologist Dr Jackie Collett and perinatal autopsy service coordinator Nicole Vander Linden, who work together at the Victorian Perinatal Autopsy Service (VPAS), at the Royal Women’s Hospital in Melbourne.Together, Jackie and Nicole emphasise the collaborative effort required to deliver effective perinatal pathology services. They also discuss the establishment of VPAS and how they have been centralising the autopsy referral process to improve the experience for bereaved families.  2024-04-2427 minAuscast MedicalAuscast MedicalEpisode 56: The Iron-Clad Chronicles | Iron StudiesIn episode 56 of This Medical Life, Dr Travis Brown and Steve Davis delve into the critical topic of iron studies, with a special focus on iron deficiency, under the expert guidance of returning guest, Professor Ken Sikaris. Iron deficiency’s prevalence is influenced by factors such as age, sex, and ethnicity, noting that women, especially those of childbearing age and pregnant women, are at higher risk. Prof Sikaris addresses the challenges and misconceptions surrounding iron studies, particularly the reliability of various tests like serum iron, transferrin saturation, and ferritin. While ferritin is the most reliable marker for to...2024-04-0854 minThis Medical LifeThis Medical LifeEpisode 56: The Iron-Clad Chronicles | Iron StudiesIn episode 56 of This Medical Life, Dr Travis Brown and Steve Davis delve into the critical topic of iron studies, with a special focus on iron deficiency, under the expert guidance of returning guest, Professor Ken Sikaris. Iron deficiency’s prevalence is influenced by factors such as age, sex, and ethnicity, noting that women, especially those of childbearing age and pregnant women, are at higher risk. Prof Sikaris addresses the challenges and misconceptions surrounding iron studies, particularly the reliability of various tests like serum iron, transferrin saturation, and ferritin. While ferritin is the most reliable marker for to...2024-04-0854 minRCPA: The Pathologists CutRCPA: The Pathologists CutS3 E2 The importance of clinical interactions when investigating perinatal lossIn the second episode of our mini-series on perinatal pathology, RCPA President Associate Professor,Trishe Leong, is joined by anatomical pathologist Dr Helen Harris and midwife, Serani Dodson, who how different professions work together to provide comprehensive care for families experiencing perinatal loss.2024-03-1219 minRCPA: The Pathologists CutRCPA: The Pathologists CutS3 E1 Use of antibiotics in childrenIn this first episode of season 3, former RCPA President, Dr Lawrie Bott, and Paediatric Infectious Diseases Specialist and Microbiologist, Dr Brendan McMullan, discuss the use of antibiotics in children and what impact a recent global shortage of antibiotics has had in Australia. 2024-01-0827 minPathPulse: Pathology Innovators in ActionPathPulse: Pathology Innovators in ActionBest Resources for Pathologists with Dr. Tristan RutlandWelcome to our fourth podcast episode! Today our guest Dr. Tristan Rutland from Australia shares what have been some of the best resources for him as a pathologist. Dr. Tristan Rutland is a highly accomplished medical educator and anatomical pathologist with a strong background in teaching and training at various levels of medical education. He graduated with distinction from the University of Wollongong in 2011 and received the prestigious Konrad Muller RCPA Outstanding Teaching Award in 2020. Dr. Rutland's teaching experience spans from first-year medical students to final-year pathology registrars, and he's actively involved in cross-specialty training for various r...2023-11-0125 minAutism ConfidentialAutism ConfidentialEpisode #048 - Richard Edley, The Need for Reality-Based Programs for Adults with Severe AutismRichard Edley, PhD is President/CEO of Rehabilitation and Community Providers Association (RCPA) of Pennsylvania, and a nationally recognized leader pushing for care options for adults with autism and I/DD. He is also the father of an adult son with profound autism. In this episode he and Jill discuss:— The scope of the I/DD system in PA and the lengthy waitlists— The pressure of increasing autism cases— Program closures and selectivity against those with acute needs; the erosion of services for high needs— The workforce (DSP) crisis— Pennsylvania's restrictive interpretation of the HCBS Settings Rule— Advocates' mania for closure...2023-10-3046 minRCPA: The Pathologists CutRCPA: The Pathologists CutS2 E8 CAR-T cell therapyIn this episode, RCPA President Dr Lawrie Bott and internationally recognised haematologist Professor Miles Prince discuss CAR-T cell therapy, a new complex and specialist treatment that is being used to cure certain types of blood cancers. 2023-09-2825 minRCPA: The Pathologists CutRCPA: The Pathologists CutS2 E7: Where would we be without perinatal pathology?In this episode, RCPA Vice President, Associate Professor, Trishe Leong, speaks with anatomical pathologist, Professor Jane Dahlstrom OAM, and specialist obstetrician and gynaecologist, Dr Farah Sethna, to discuss perinatal pathology and its role in trying to give answers to women, their families and the treating team when there has been an adverse outcome of a pregnancy. 2023-08-2420 minDoctor NOSDoctor NOS98 | Dr. Elizabeth Roberts on adventure sports, training & anatomical pathologyDr. Elizabeth Roberts is a Nelson-based anatomical pathologist who has worked both for Te Whatu Ora and MedLab South. She graduated from Otago University and pursued pathology training with Auckland, Oregon Health Science University, and Harvard University. She works part-time, and is the past treasurer of the RCPA NZ committee. She has many other passions, including mountain biking, kitesurfing, tramping, climbing, hunting and trapping pests. Since the recording of the episode, Dr. Roberts is now Vice President of the RCPA. In this episode, we discuss her journey into anatomical pathology and the training required, her choice for p...2023-08-1040 minRCPA: The Pathologists CutRCPA: The Pathologists CutS2 E6: Chronic traumatic encephalopathy (CTE) and it links to participation in contact sportsIn this episode of the Pathologists Cut, RCPA President Dr Lawrie Bott catches up with Associate Professor Michael Buckland to discuss chronic traumatic encephalopathy (CTE) and it links to participation in contact sports. They discuss how it manifests pathologically, and what current research tells us about diagnosis and recognition of the condition.A/Prof Buckland is Head of the Department of Neuropathology at Royal Prince Alfred Hospital. He is the founder and Director of the Australian Sports Brain Bank, Co-Director of the Multiple Sclerosis Australia Brain Bank, and Head of the Molecular Neuropathology Program at the Brain...2023-05-2325 minRCPA: The Pathologists CutRCPA: The Pathologists CutS2 E5: Self-Collection for Cervical ScreeningIn our fifth episode of season 2, RCPA President Dr Lawrie Bott and Prof Marion Saville, Executive Director at the Australian Centre for the Prevention of Cervical Cancer, discuss the introduction of self-collection to Australia’s cervical screening program. 2023-04-1119 minMoral MattersMoral MattersLobbying for Good | S6: Episode 1 | Richard Edley, PhDDr. Richard Edley is a psychologist who has been the lead executive for Rehabilitation and Community Providers Association, a lobbying organization in Pennsylvania that supports federally qualified health centers. He shares his journey to this career, and why we should all learn more about how lobbyists - and even political action committees - might be acting on our behalf. More information about RCPA: paproviders.org To support the podcast: https://www.fixmoralinjury.org/get-started Twitter - @fixmoralinjury Instagram - @moralinjury Facebook - @moralinjuryofhc LinkedIn - @moral Injury...2023-02-2335 minRCPA: The Pathologists CutRCPA: The Pathologists CutS2E4: The UK blood donor deferral has lifted. What does this mean for Aussie donors?A rule banning many former UK residents and visitors from giving blood in Australia has lifted. What does this mean for Australian blood donors and the donor blood supply? In our fourth episode of season two, RCPA President Dr Lawrie Bott discusses this with Lifeblood's Professor Iain Gosbell.2022-10-2420 min🇫🇷 Ask Stago (version française)🇫🇷 Ask Stago (version française)🇫🇷 S2E9 - Le B.A.BA du prélèvement sanguin pour l’hémostaseBienvenue chez « Ask STAGO », le Podcast fournissant des réponses d'expert à vos questions d'expert en hémostase. Dans l'épisode d'aujourd'hui, Marie-Louise Alonso, longtemps coordinatrice de l’Hopital Maisonneuve-Rosemont de Montréal partagera avec nous les conseils utiles pour réaliser un prélèvement sanguin pour la paillasse d’Hémostase dans les meilleures conditions.   Pour en savoir plus :   Stability of coagulation proteins in frozen plasma. B. Woodhams, O. Girardot, MJ Blanco and Y.Gourmelin, Blood coagulation and fibrinolysis 2001, 12:229-236  Effects of storage time and temperature on coagulation tests and factors in fresh plasma Limin Feng, Ying...2022-09-2215 minRCPA: The Pathologists CutRCPA: The Pathologists CutS2E3: Head and Neck Cancer with Prof Ruta GuptaIn our third episode, RCPA President Dr Lawrie Bott and Prof Ruta Gupta discuss head and neck cancers. Traditionally the most frequent cause of head and neck cancer has been smoking and alcohol. However, with smoking on the decline in Australia, what else can cause these cancers?2022-08-1219 minRCPA: The Pathologists CutRCPA: The Pathologists CutS2E2: Colds, flu & COVID: How can we protect ourselves this winter?In the second episode of season 2, Prof Peter Collignon and Dr Lawrie Bott discuss why 2022 brings a unique cold and flu season and the measures we can take to avoid respiratory viruses this winter.Copyright © 2022 The Royal College of Pathologists of Australasia. All rights reserved.2022-06-2826 minAuscast MedicalAuscast MedicalEpisode 19: Gout & Hyperuricaemia | Affluent AfflictionsAncient Egyptians called it podagra (foot-trap), Hippocrates the unwalkable disease, and the 17th and 18th century it became known as the Disease of Kings. Gout has long been associated with rich foods and an affluent lifestyle. Yet, its significance in the modern era cannot be overstated. Commonly thought of a joint disease, the systemic impact are becoming increasingly apparent. Join us as we discuss the significance of gout for patients and the importance of diet, treatment and management. Our special guests include: Professor Richard Johnson is a physician in internal medicine, renal, and...2022-06-211h 12This Medical LifeThis Medical LifeEpisode 19: Gout & Hyperuricaemia | Affluent AfflictionsAncient Egyptians called it podagra (foot-trap), Hippocrates the unwalkable disease, and the 17th and 18th century it became known as the Disease of Kings. Gout has long been associated with rich foods and an affluent lifestyle. Yet, its significance in the modern era cannot be overstated. Commonly thought of a joint disease, the systemic impact are becoming increasingly apparent. Join us as we discuss the significance of gout for patients and the importance of diet, treatment and management. Our special guests include: Professor Richard Johnson is a physician in internal medicine, renal, and...2022-06-211h 13Auscast MedicalAuscast MedicalEpisode 15: Lynch Syndrome & Hereditary Non Polyposis Colon Cancer (HNPCC) | Premonitions of a SeamstressPauline Gross was a seamstress in 1895 who had seen family members die at an early age from cancer. At the time, one of her clients was a pathologist by the name of Dr Aldred Scott Warthin and confided in him her fear that that this would be her fate too. The two combined to record the most comprehensive family history ever created. Dr Warthin called them ‘Family G’. In the 1960s, Dr Henry T Lynch who revived the search for the members of Family G. Through family gatherings and meetings, he managed to track down over 650 family memb...2022-04-261h 17This Medical LifeThis Medical LifeEpisode 15: Lynch Syndrome & Hereditary Non Polyposis Colon Cancer (HNPCC) | Premonitions of a SeamstressPauline Gross was a seamstress in 1895 who had seen family members die at an early age from cancer. At the time, one of her clients was a pathologist by the name of Dr Aldred Scott Warthin and confided in him her fear that that this would be her fate too. The two combined to record the most comprehensive family history ever created. Dr Warthin called them ‘Family G’. In the 1960s, Dr Henry T Lynch who revived the search for the members of Family G. Through family gatherings and meetings, he managed to track down over 650 family memb...2022-04-261h 18RCPA: The Pathologists CutRCPA: The Pathologists CutS2E01: What happened in the lab last summer?In the first episode of season 2, Dr Michael Dray reflects on his 'pandemic presidency' with Dr Lawrie Bott and the six things that overwhelmed the system.Copyright © 2022 The Royal College of Pathologists of Australasia. All rights reserved.2022-04-0817 minThis Medical LifeThis Medical LifeEpisode 7: Medical Education | Exponential ChallengesHow we teach those who come after us is as important as the knowledge we learn for ourselves. Medicine throughout the ages has been an apprenticeship style model, but over the last few hundred years this has changed to tertiary education. However, is this the right model? Our special guest is Dr Tristan Rutland who is an Anatomical Pathologist at Liverpool hospital and teaches at Western Sydney University. He was the recipient of the Konrad Muller RCPA award for Outstanding Teaching in 2020. He is also very active on Twitter (@TristanRutland7) posting #Tweetorials and Pathology Education. ...2022-01-0446 minRCPA: The Pathologists CutRCPA: The Pathologists CutE7: What is pharmacogenetics? Professor Graeme SuthersIn the final episode of this season,  past RCPA President Dr Michael Dray speaks with Prof Graeme Suthers. Prof Suthers is the National Director for Sonic Genetics and is one of Australia's most respected experts in the field of genetics.  This episode delves into the world of pharmacogenetics and its demonstrated clear benefits. Pharmacogenetics is standard practice in many other countries, it is still underrepresented in Australia and New Zealand.Copyright © 2021 The Royal College of Pathologists of Australasia. All rights reserved.2021-12-1232 min