Shows
Usher - Audio BiographyUsher's Fashion Dominance: Ralph Lauren, Met Gala, and Relentless SuccessUsher BioSnap a weekly updated Biography.Usher has had a headline-grabbing few days marked by a blend of high fashion, major brand partnerships, high-profile appearances, and ongoing touring success. On July 16, Usher was named the new face of Ralph Lauren’s just-launched Ralph’s Club New York Eau De Parfum. This marks his first-ever fragrance campaign and the first time Ralph Lauren has selected a major music icon for such a role. In the words he shared with L’Officiel, Usher reflected on representing the energy and style of New York City for an iconic designer as something he see...2025-07-2303 min
Punch Drunk NerdOur Thoughts on 28 Years Later and the New James Bond Director - EP 166Grab your blow darts and slather up in iodine because the boys are reviewing 28 YEARS LATER! Now that the rage virus has had time to evolve, the nerds catch up on all the new and terrifying things that have taken hold in the UK. And spoiler alert it’s not just the beans on toast!Plus with the news of Denis Villeneuve taking helm of the James Bond franchise’s next installment, the nerds let out some frustrations. One of them gets particularly shaken, not stirred. Then there is some casting news with Jon Berenthal join...2025-06-271h 56
The Alzheimer’s Solution Revolution PodcastCognitive Super-agers-Part 1—The Epigenetic BridgeGreetings everyone!This is your host, Ralph Sanchez.Today I am finally delivering on a preview note from my last episode in which I promised to provide an overview on what it takes to become a cognitive super-ager and truly live younger, longer.Thus, I am very much looking forward to bringing you this review here today with regard to longevity and healthspan, and what more specifically underlies the capacity for anyone to attain a cognitive super-ager’s health and wellness lifespan (healthspan) if you think ahead.The science of getting ol...2025-06-031h 53
The MotorCity Crowns PodcastEpisode 23 -Ralph Perez : Podcaster Series Vol 2Join me as I sit down with Ralph Perez—Detroit-based marketing strategist, creative director, and host of Inside The Pulse. In this episode, we delve into his journey through media, branding, and his mission to amplify community voices through storytelling.Discover how Ralph is shaping narratives and driving impact in the heart of Detroit.2025-04-181h 26Punch Drunk NerdWE’RE BACK TOGETHER (Special Episode) - Batman 2 Delay and Nosferatu Review - Ep. 139Things get messy in this episode.
We move through time and space as we talk about The Batman 2 Delay, James Gunn, Chat GPT and of course Robert Eggers Nosferatu (Lily - Rose Depp, Bill Skarsagård, Willem Dafoe, Nicholas Hoult, Emma Corrin, Ralph Ineson, Aaron Taylor - Johnson)
Sorry for the sound, we were flying free and blind. 2025-01-031h 09
Writing in the DarkSeason 2, Episode 11, Burning Bright long after JupiterIn this emotional episode, Julia F. Green and Ralph Walker reconnect with three writers who attended the Journey to Jupiter retreat: historical fiction writer Susan Klobuchar (Instagram, Bluesky, Substack), UCLA student Meredith Parker Fenwick, and YA writer Shawn T. Anderson. They discuss their transformative experiences at the retreat, the importance of creative community, how their writing progressed at and after the retreat, and how they navigate uncertain and challenging times as artists. Tune in for a raw and unfiltered dialogue on finding inspiration, fostering community, and burning bright through dark times. Books discussed:2024-12-1330 min
El CartoonscopioEL CARTOONSCOPIO 73 - Ralph Bakshi: La transgresión animada (y III)Llegamos a la tercera y última entrega dedicada a revisar la apasionante filmografía del realizador estadounidense Ralph Bakshi (1938), un autor siempre audaz en sus decisiones que se convirtió en el indiscutible pionero de la animación expresamente realizada para adultos. En esta etapa final, hablamos de su regreso a la televisión con la rompedora recuperación en 1987 del clásico Súper Ratón y sus nuevas aventuras, varios pilotos fallidos y la provocadora serie “Spice City” (1997). Y entre medias, “Cool World” (1992) su último largometraje. Un legado imprescindible que los cartoonscopistas Cruz Delgado Sánchez, Alfons Moliné, Federico Alba, Francisco Javi...2024-11-301h 56
DESCIFRANDO EL ARTESe trata de ser mejor cada díaHoy hablamos sobre la mejora constante en el arte. Muchos artistas se sienten abrumados al compararse con otros más experimentados, pero esa comparación no debe ser paralizante. Lo esencial no es ser "el mejor" desde el inicio, sino mejorar cada día. Ser artista es un camino lleno de aprendizaje, y cada esfuerzo nos acerca a nuestra propia voz creativa.
Tu evolución artística no es una competencia con los demás, sino un viaje personal hacia la mejora continua. Para mantenerte enfocado en tu crecimiento, acepta los errores como parte del proceso, establece metas...2024-09-2904 min
Dark OriginsOlympic Crime: The Murder of Keishla Rogriguez Ortiz by Felix VerdejoKeishla Rodriguez Ortiz met Felix Verdejo when the two of them were very young, because they attended the same school growing up. Their friendship blossomed into a romantic relationship when they were in high school. Keishla loyally supported Félix as he chased his dreams to become a professional boxer. At 18 years old Félix qualified for the 2012 olympics. He didn’t end up medaling but a professional spot was waiting for him when he got home to Puerto Rico. The beginning of his professional career was explosive. He held the WBO lightweight title for multiple years. He was expe...2024-08-1530 min
El CartoonscopioEL CARTOONSCOPIO 69 - Ralph Bakshi: La transgresión animada (II)Abordamos la segunda entrega de nuestro estudio de la filmografía del realizador Ralph Bakshi (1938), una obra siempre arriesgada y sorprendente. En esta ocasión analizamos tres largometrajes pertenecientes al subgénero de espada y brujería (“Los hechiceros de la guerra”, “El señor de los anillos” y “Tygra, hielo y fuego”) y dos con los que Bakshi volvió a fijarse en los cambios de la sociedad estadounidense del siglo XX, con importante presencia de la música (“American Pop” y “Hey Good Lookin’”). Un recorrido por una interesante etapa de consolidación del estilo de su autor a cargo de un equipo formado por...2024-07-281h 58
#1 Show - BizBuzz: Igniting SuccessRalph Sanchez - Diabetic Brain/BrainDefendRalph Sanchez, MTCM, CNS, D.Hom. TheAlzheimersSolution.com BrainDefend LLC from Carmel, CA in Diabetic Brain/BrainDefend with Host, Arnie Fonseca, Jr. Life Strategist.www.NEWStreamingNetwork.com. Home of NEW Streaming TV, Going Bold Media, Going Solo Media. and WGSN-DB Going Solo Network Radio, Podcasts, and TV.Become a supporter of this podcast: https://www.spreaker.com/podcast/1-show-bizbuzz-igniting-success--2225865/support.2024-06-2950 min
Thoughtful in The DarkTill The Day They ReturnSend us a textSeparating from loved ones can be a difficult experience. For parents, however, separating from their children is an entirely different and painful experience. In this special Father's Day episode, I discuss this type of separation. Having experienced it on a personal level, I am able to empathize with those who have experienced the same. I wish all my brothers a Happy Father's Day. Here's one for us! — RalphMUSIC by: JUAN SANCHEZ MUSICOfficial Facebook Page2024-06-1606 minThe Alzheimer’s Solution Revolution PodcastThe Bone-Heart-Brain Axis in the Risk for Alzheimer’s Disease and Dementia – Part 2Episode #22—Where We Left OffI’ll begin this episode by sharing an excerpt of the primary outcome from study #1 that I reviewed in part #1—#22—of this two part episode series.In that study, the authors found “a positive association between OC [plasma osteocalcin levels] and working memory capacity, executive functioning and global cognition scores.”Study #2—ExcerptThe authors of study #2 remarked “we observed that in both older adults with osteopenia and older adults with AD [Alzheimer’s disease] as compared to...2024-03-281h 05
Download New Full Audiobooks in Romance, Modern[Spanish] - Ralph. Pasión, desenfreno y amor by Dani VeraPlease visit https://thebookvoice.com/podcasts/1/audiobook/764491 to listen full audiobooks. Title: [Spanish] - Ralph. Pasión, desenfreno y amor Series: #2 of Security Miller Author: Dani Vera Narrator: Pedro M. Sánchez Format: Unabridged Audiobook Length: 12 hours 59 minutes Release date: March 25, 2024 Genres: Modern Publisher's Summary: Cuando el deber y el amor no pueden reconciliarse.Los lectores opinan:Totalmente adictiva. Una montaña rusa de sentimientos muy intenso. Merypoppins.Intensa, brutal, sentimientos a flor de piel, emociones por doquier y amor.... Alguien da más??? Eva.Ralph es un francotirador de élite que se ha visto obligado a infiltrarse en la peligr...2024-03-2505 min
Explore New Full Audiobooks in Fiction, Action & Adventure[Spanish] - Ralph. Pasión, desenfreno y amor by Dani VeraPlease visit https://thebookvoice.com/podcasts/1/audiobook/764491 to listen full audiobooks. Title: [Spanish] - Ralph. Pasión, desenfreno y amor Series: #2 of Security Miller Author: Dani Vera Narrator: Pedro M. Sánchez Format: Unabridged Audiobook Length: 12 hours 59 minutes Release date: March 25, 2024 Genres: Action & Adventure Publisher's Summary: Cuando el deber y el amor no pueden reconciliarse.Los lectores opinan:Totalmente adictiva. Una montaña rusa de sentimientos muy intenso. Merypoppins.Intensa, brutal, sentimientos a flor de piel, emociones por doquier y amor.... Alguien da más??? Eva.Ralph es un francotirador de élite que se ha visto obligado a infiltrarse en la pel...2024-03-2505 min
Explore New Full Audiobooks in Fiction, Action & Adventure[Spanish] - Ralph. Pasión, desenfreno y amor by Dani VeraPlease visithttps://thebookvoice.com/podcasts/1/audiobook/764491to listen full audiobooks.
Title: [Spanish] - Ralph. Pasión, desenfreno y amor
Series: #2 of Security Miller
Author: Dani Vera
Narrator: Pedro M. Sánchez
Format: Unabridged Audiobook
Length: 12 hours 59 minutes
Release date: March 25, 2024
Genres: Action & Adventure
Publisher's Summary:
Cuando el deber y el amor no pueden reconciliarse.Los lectores opinan:Totalmente adictiva. Una montaña rusa de sentimientos muy intenso. Merypoppins.Intensa, brutal, sentimientos a flor de piel, emociones por doquier y amor.... Alguien da más??? Eva.Ralph es un francotirador de élite que se ha visto obligado a infiltrarse en la peligr...2024-03-2512h 59
Grab the Essential Free Audiobooks in Romance, Mystery[Spanish] - Ralph. Pasión, desenfreno y amor by Dani VeraPlease visit https://thebookvoice.com/podcasts/1/audiobook/764491 to listen full audiobooks. Title: [Spanish] - Ralph. Pasión, desenfreno y amor Series: #2 of Security Miller Author: Dani Vera Narrator: Pedro M. Sánchez Format: Unabridged Audiobook Length: 12 hours 59 minutes Release date: March 25, 2024 Genres: Mystery Publisher's Summary: Cuando el deber y el amor no pueden reconciliarse.Los lectores opinan:Totalmente adictiva. Una montaña rusa de sentimientos muy intenso. Merypoppins.Intensa, brutal, sentimientos a flor de piel, emociones por doquier y amor.... Alguien da más??? Eva.Ralph es un francotirador de élite que se ha visto obligado a infiltrarse en la peligr...2024-03-2505 minGrab the Essential Full Audiobooks in Romance, Mystery[Spanish] - Ralph. Pasión, desenfreno y amor by Dani VeraPlease visithttps://thebookvoice.com/podcasts/1/audiobook/764491to listen full audiobooks.
Title: [Spanish] - Ralph. Pasión, desenfreno y amor
Series: #2 of Security Miller
Author: Dani Vera
Narrator: Pedro M. Sánchez
Format: Unabridged Audiobook
Length: 12 hours 59 minutes
Release date: March 25, 2024
Genres: Mystery
Publisher's Summary:
Cuando el deber y el amor no pueden reconciliarse.Los lectores opinan:Totalmente adictiva. Una montaña rusa de sentimientos muy intenso. Merypoppins.Intensa, brutal, sentimientos a flor de piel, emociones por doquier y amor.... Alguien da más??? Eva.Ralph es un francotirador de élite que se ha visto obligado a infiltrarse en la peligrosa mafia...2024-03-2512h 59
Join Up Dots - Business Coaching Made Easy (With A Bit Of Life Coaching Too)LIFE COACHING: Great Things Happen When You RelaxLIFE COACHING: Great Things Happen When You Relax Welcome to Join Up Dots, where we unravel the mysteries of life and discover the magic hidden in the mundane. In today's episode, we're diving deep into the transformative power of the backwards law, where the less you stress, the more you achieve. #BackwardsMagic #StressLessAchieveMore We've received heartwarming stories from listeners like Sarah Thompson from Willow Grove, Illinois, who landed her dream job when she stopped obsessing over it. #DreamJobSurprise Michael Chang from Maplewood, New Jersey, found love when he least expected it, reminding us that sometimes, love finds us when we're...2024-03-1514 min
El CartoonscopioEL CARTOONSCOPIO 64 - Ralph Bakshi: La transgresión animada (I)Si ha habido un realizador dispuesto a ignorar todas las normas y tabús que durante años dominaron en el cine de animación, ese ha sido sin duda Ralph Bakshi (1938). Desde sus inicios, intentó revolucionar el cartoon convencional durante su estancia en los estudios Terrytoons y Paramount para después, ya de forma independiente, convertirse en un defensor del largometraje dirigido expresamente a un público adulto con títulos como “Fritz the Cat”, “Heavy Traffic” o “Coonskin”. Una primera etapa de temática más urbana y social, con abundante dosis de erotismo, que será analizada por Cruz Delgado Sánchez...2024-02-251h 56
Un home 10, amb Jau Fibla592 #UnHome10 Grossa de Nadal: pa i circ! Sánchez i Feijóo: La comèdia! Els Kidults, Ralph Fiennes!Avui, en l'episodi del vídeo pòdcast diari "Un home 10" presentat pel talentós Jau Fibla, l'entreteniment del dia es converteix en una experiència inoblidable per a tota l'audiència de parla catalana.
🌟🎙️
En aquest Dia Mundial del Termòmetre, el programa ofereix una mescla de seccions que prometen ser tan variades com les fluctuacions meteorològiques.
☀️🌡️
La Grossa de Nadal ocupa un lloc destacat, amb una reflexió aguda sobre el significat de "pa i circ". El programa examina els detalls d'aquesta tradició tan esperada.
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La reunió entre Pedro Sánchez i Alberto Núñez Feijóo promet ser un tema candent, amb el programa...2023-12-2850 minUn home 10, amb Jau Fibla592 #UnHome10 Grossa de Nadal: pa i circ! Sánchez i Feijóo: La comèdia! Els Kidults, Ralph Fiennes!Avui, en l'episodi del vídeo pòdcast diari "Un home 10" presentat pel talentós Jau Fibla, l'entreteniment del dia es converteix en una experiència inoblidable per a tota l'audiència de parla catalana.
🌟🎙️
En aquest Dia Mundial del Termòmetre, el programa ofereix una mescla de seccions que prometen ser tan variades com les fluctuacions meteorològiques.
☀️🌡️
La Grossa de Nadal ocupa un lloc destacat, amb una reflexió aguda sobre el significat de "pa i circ". El programa examina els detalls d'aquesta tradició tan esperada.
🎄🎉
La reunió entre Pedro Sánchez i Alberto Núñez Feijóo promet ser un tema candent, amb el programa...2023-12-2850 minThe Alzheimer’s Solution Revolution PodcastThe Bone-Heart-Brain Axis in the Risk for Alzheimer’s Disease and Dementia—Part 1Hello once again!This is your host Ralph Sanchez, and welcome to episode #22 and indeed, it has been much too long between this episode and the last one.I have been busy with new book projects on the key underlying risk factors for late-onset Alzheimer’s disease that are unique to women.I’ll have an announcement on when those books will be available here soon, and frankly, I'm looking forward to doing so.And on that note, I have in store for you another special episode today in which I’ll pre...2023-12-211h 11
Join Up Dots - Business Coaching Made Easy (With A Bit Of Life Coaching Too)LISTENER SUCCESS: Unveiling the Recipe for Perfect Business Ideas WorldwideLISTENER SUCCESS: Unveiling the Recipe for Perfect Business Ideas Worldwide 🎧 Listen in and get inspired by our incredible listeners from around the globe, who joined us on this special episode of Join Up Dots! We've received an array of fascinating questions from aspiring entrepreneurs seeking guidance on crafting the perfect business idea. 1️⃣ Sarah Thompson from Brighton, UK, wonders how to identify the most impactful business idea. #BrightonBusiness #PositiveImpact 2️⃣ Jake Ramirez hailing from Austin, Texas, USA, seeks advice on narrowing down business ideas and avoiding overwhelm. #AustinEntrepreneur #FocusOnOne 3️⃣ Emily Chen sends warm greetings from Vancouver, Canada, as she looks to create a unique sellin...2023-08-0227 min
My New Favorite Olympian and My New Favorite ParalympianTeam USA’s Sofia Huerta and Ashley Sanchez: Am I Mexican enough?Sofia Huerta and Ashley Sanchez, who are poised to be the only two Mexican Americans to represent the U.S. at the World Cup, are grappling with their hybrid identities. Hear from:Sofia HuertaAshley SanchezKarina Rodríguez (Mexican national team and Ashley’s collegiate teammate)Ralph Sanchez (Ashley’s father) Episode reporter:Annabelle Sedano (NBC and Telemundo Los Angeles)Watch the episode HERE.
2023-06-2820 min
This Is Your Mind RantingThe Cost of Negligence: My Thoughts on Ralph Yarl I hate to admit that sometimes anti-gun supporters are right about guns being used irresponsibly. In today's episode, I give my thoughts on Gabby Giffords of the Giffords Law Center to Prevent Gun Violence tweeting about the gross negligence of a firearm by a 85-year-old man that put a young man in the hospital for ringing a doorbell. We gun owners got to do better when it comes to defending ourselves legally. Events like this just gives the gun control supporters more leverage.
Here is a link to the article and story: https://www...2023-04-2022 min
Perpetual Traffic[Best of 2022] Episode 356: Creating the Perfect High Converting Tik Tok Ad with Savannah SanchezIt’s a rare thing to find a TikTok advertising genius who generously shares her secrets with the world for free, but we found one. In today’s episode, co-hosts Ralph Burn and Kasim Aslam sit down with Savannah Sanchez, a freelancer who helps e-commerce businesses with TikTok—from ad strategies to driving conversions to developing creatives. It’s never been easier to be inspired, Savannah says, and she’s got a handful of TikTok formulas that have worked consistently across all brands, even as the world keeps changing around us. Listen in for...2023-01-0358 minThe Alzheimer’s Solution Revolution PodcastEstrogen(s) in the Risk for Alzheimer’s—The Kind You Make, The Kind You Take, and The Kind You Eat.Welcome! This is your host Ralph Sanchez, and this is episode #21, I am expanding on the last episode, #20, titled: “Estrogen Deficiency and Cardiometabolic Disease Underlies a Woman's Greater Risk for Alzheimer's Disease”. This episode—part two of this two-part episode series—on the linkages between perimenopausal and postmenopausal estrogen declines in women and the risk for age-related disorders— will focus primarily on three types of estrogen:Endogenous estrogen (the kind you make).Estrogen replacement therapies (the kind you take), andPhytoestrogens (the kind you eat and supplement with),and what they potenti...2022-11-011h 57The Alzheimer’s Solution Revolution PodcastEstrogen Deficiency and Cardiometabolic Disease at Midlife Underlies a Woman’s Greater Risk for Alzheimer’s DiseaseWelcome!This is your host Ralph Sanchez, and this is episode #20 here at The Alzheimer's Solution Revolution podcast channel. Today we are expanding on and diving a little deeper into two primary risk factors associated with an increased risk for dementia and late-onset Alzheimer's disease (LOAD) in women—cardiometabolic disease and postmenopausal estrogen deficiency in women. In my book, and in episode #10 here on this channel, I covered the critical role that estrogen plays in glucose metabolism and its role in glucose hypometabolism. In that episo...2022-10-0455 min
The Medical InsiderAlzheimer's with Ralph SanchezAs years pass by, the number of people with Alzheimer's increases. That's why medical experts are researching and studying the possible causes. In this episode of Medical Insider, Ralph Sanchez and I talk about why women are more prone to dementia than men, approaches and exercises that can help you with Alzheimer's, and many more!More information on Ralph Sanchez, his books and his BrainDefend® Body-Brain Renewal programs are available at www.TheAlzheimersSolution.com and BrainDefend.comStay tuned for more exciting and insightful episodes! Follow and subscribe to our podcast using the links below ⏬⏬⏬ 2022-10-0330 min
Scientifically Sound: Hosted by Ralph White IIIEpisode 9: Oh September, Do You Remember? feat Daniela Mesa and Haley StubbsWelcome Back, Welcome Back, Welcome Back!Daniela Mesa and Haley Stubbs come back to the Sound one mo' time! We catch up on what they've been up to since their last appearance, try and create a science awards show, and discuss the hit "September" by Earth Wind and Fire. What we decided to do is look into what happened on September 21st from a scientific point of view! You'll laugh, you'll learn, you'll probably find out more stuff about us that you can laugh about.Haley Stubbs is a 6th year PhD candidate in the Q...2022-09-2951 minThe Alzheimer’s Solution Revolution PodcastViagra and Cialis in the Risk Reduction for Alzheimer’s—An Unfinished StorySummary Hello and welcome to episode #19! This is Ralph Sanchez and today I’ll be talking the outcomes of two recent studies that investigated the potential use of Viagra and Cialis in the risk reduction for late-onset Alzheimer’s disease (LOAD). I was in part inspired to provide an overview on these two recent studies as they are cautionary tales on how many studies do not include the interrelated factors that are essential in arriving to an integrated assessment and analysis that serves their very premise— which is, does...2022-09-191h 07
Tech Whisperers: Inside the Playbooks of the Best Digital LeadersCutting Through the Noise as a Digital Leader with Lumentum's SVP CIO, Ralph Loura, Part 1We had an incredible opportunity to sit down in person with Ralph Loura, the SVP CIO at Lumentum, for a special two-part conversation at The CIO 100 Awards in Rancho Palos Verdes, CA. Ralph’s leadership journey encompasses some of the most well-known technology and consumer products companies around. Along the way, he’s been recognized time and again as an inspiring, transformational CIO whose innovative approaches create real business value.But that’s not all there is to Ralph Loura. He also plays a few other vital “roles” for his team: the Chief Truth Telling Officer, Chief Storytelling Officer, Chief Moti...2022-09-0735 minTech Whisperers: Inside the Playbooks of the Best Digital LeadersCutting Through the Noise as a Digital Leader with Lumentum's SVP CIO, Ralph Loura, Part 2We are back for part 2 of our two-part episode with Ralph Loura, recorded onsite at The CIO 100 Awards held at the Terranea Resort in Rancho Palos Verdes, CA.Ralph is the SVP CIO at Lumentum and has worked at companies like HP, Cisco Systems, and Clorox, and he serves as an advisory board member for several more. In part 1, we unpacked how Ralph approaches truth-telling and storytelling for effective communication. In part 2 we’re exploring Ralph’s career journey more closely and digging in to the importance of mindset, getting out of your comfort zone, and Ralph’s path toward...2022-09-0731 minThe Alzheimer’s Solution Revolution PodcastBrain Detoxification—Part 3—Autophagy and the Synergistic Proteasomal Degradation System in Brain DetoxificationSummary Welcome! This is Ralph Sanchez and today I’ll be expanding on the last two episodes—#16 & #17—in this special brain detoxification series. This is the third or part three in that series. In our last two brain detoxification episodes I described the pathways of beta-amyloid and tau protein transport and clearance from the brain, and in their degradation in the liver in what I describe as the liver-brain axis in Alzheimer’s disease. Today I’ll provide an overview on two related and crucial me...2022-09-0553 minThe Alzheimer’s Solution Revolution PodcastBrain Detoxification—Part 2—The Gut-liver-Brain AxisSummary Hello and welcome to episode #17!This is Ralph Sanchez and today I’ll be expanding on the first episode’s overview with regard to beta-amyloid and tau protein clearance and detoxification.If you did not catch that episode (#16), I provided an in-depth overview on the role of the blood brain barrier (BBB) and the glymphatic system in clearing and transporting toxic beta-amyloid and tau protein from the brain.In today’s episode, I’ll review the emerging science and research with regard to the brain-liver axis in beta-amyloid clearance...2022-08-2357 minThe Alzheimer’s Solution Revolution PodcastBrain Detoxification—Part 1—The Role of the Blood Brain Barrier and The Glymphatic SystemSummary Hello and welcome to episode #16! Today I’ll be describing an elemental aspect in maintaining a healthy brain as you age and preventing the cognitive decline that is associated with unhealthy aging and the risk for Alzheimer’s disease as you age—brain detoxification. Because brain detoxification mechanisms are a very complex review, I will provide it in three parts–this episode and the next two. Now, most people that are oriented toward health and wellness strategies know that a good detox for their bo...2022-08-0945 minThe Alzheimer’s Solution Revolution PodcastMedical Foods and Nutraceuticals That Optimize Cognitive Function and Reduce the Risk for Late-Onset Alzheimer’s disease.Summary Today, I'll review the formulations and research that illustrates the role of medical foods which are a unique classification of formulations that are approved by the FDA. Additionally, I will speak to the potential value of nutraceuticals and supplemental food-derived products in supporting cognitive health in aging individuals at risk for late-onset Alzheimer's disease (LOAD). And what are medical foods? Medical foods are defined products and nutrient formulations that are specifically designed for the dietary management of a disease. Medical food products are...2022-07-2646 minThe Alzheimer’s Solution Revolution PodcastThe Vital Role of Diet-Derived Phytochemicals in the Protection Against Dementia and Alzheimer’s in AgingSummaryIn today’s episode (#14), I’ll be providing an in depth overview one of the most powerful factors that underlies healthy body and brain aging—DIET!Indeed, healthy foods provide key nutrients and phytochemicals work to optimize cognitive function, and protect against dementia and Alzheimer’s in aging.However, since dietary therapies and specific foods in those diets that are linked to healthy aging is such a huge field of research, I’ll be focusing on a particular diet that has become a meaningful food template for the preservation and enhancement of brain heal...2022-07-1139 minThe Alzheimer’s Solution Revolution PodcastGlucose Hypometabolism, Impairments in Mitochondrial Function, and Oxidative Stress as Major Risk Factors for Alzheimer’s Disease.SummaryToday I am very much looking forward to pod-talking about one of the most important components associated with accelerated aging processes, and in the risk for Alzheimer’s disease— the decline and inhibition of critical energy metabolism systems of the body and brain. Many studies have shown that alterations in mitochondrial energy metabolism, or bioenergetics, have been linked to numerous disorders that disrupt normal metabolism, and it is a factor in brain aging and a number of neurodegenerative diseases such as Alzheimer’s. Aging is associated with progressive mitochon...2022-06-2829 minThe Alzheimer’s Solution Revolution PodcastDHEA, Pregnenolone and the DHEA to Cortisol Ratio in Longevity Wellness and the Protection and Optimization of Cognitive FunctionSummaryThis episode (#12) continues the overview of neurosteroids and their critical function in the protection and enhancement of cognitive function.In episode #11, I reviewed the role of “Testosterone, Progesterone and Allopregnanolone—Critical and Timely Neurosteroid Interventions in the Risk Reduction of Alzheimer's Disease.”, and this podcast will add DHEA and pregnenolone to that overview.The focus today will center around the pressing fact that the declines of steroid hormones such as DHEA and pregnenolone have pronounced effects on brain and longevity wellness.DHEA, pregnenolone, estrogen and progesterone and other hormones in anti-a...2022-06-2125 minThe Alzheimer’s Solution Revolution PodcastTestosterone, Progesterone and Allopregnanolone—Critical and Timely Neurosteroid Interventions in the Risk Reduction of Alzheimer’s Disease.In women, how important of a role does progesterone play in cognitive function?While a number of studies have shown that estrogen replacement therapy in women is protective against the risk for late-onset Alzheimer's disease (LOAD), only a few studies have demonstrated that progesterone also benefits cognitive function.Indeed, progesterone could be important in preserving cognitive function in women as they age—particularly in the menopausal transition when there is a precipitous drop in progesterone.Studies that investigated the protective role of hormone replacement therapy (HRT) in the potential prevention of LOAD have th...2022-06-1426 minThe Alzheimer’s Solution Revolution PodcastWhy Low Estrogen Levels in Women is Linked to an Increased Risk for Alzheimer’s DiseaseIn the U.S., two-thirds of diagnosed cases of dementia and Alzheimer's disease are women.A number of studies have shown that lower estrogen levels "before, during, and after menopause" is a risk for late-onset Alzheimer's disease.However, the risk factors associated with declining estrogen levels and late-onset Alzheimer's disease in women as they age is not widely known.Estrogen is a regulator of glucose metabolism in women and brain estrogen deficiency sets in motion a brain energy metabolism crisis in women—particularly after menopause.A decline in estrogen in menopause is...2022-06-0631 min
Punch Drunk NerdStar Wars Celebration 2022 and Obi Wan Kenobi Discussion - EPISODE #13Star Wars Celebration brought a ton of news this past weekend and we are here to talk about it! We also talk about the return of Obi Wan and Darth Vader in the Disney+ show, Obi-Wan Kenobi.
We chat about some new tv / movie trailer like (Netflix) Man Vs Bee and The Menu (Anna Taylor Joy, Ralph Fiennes, Nicholas Hoult), Pinocchio, Winnie the Pooh: Blood and Honey and everything we’ve been into like: Marvelous Mrs Maisel, Barry, Jedi Fallen Order, Top Gun Maverick, and Fantastic Beasts: The Secrets of Dumbledore.
STAR WAR...2022-06-032h 26The Alzheimer’s Solution Revolution PodcastModifiers of the Gut-Brain Axis in the Risk for Dementia and Alzheimer’s DiseaseThe Gut-Brain Axis—what does that connection represent? Well, the gut-brain connection is often described as a bidirectional highway that is linked to many cause and effect health consequences, and many studies have explored the impact of the gut environment and microbiome on brain health in that gut-brain dynamic. Indeed, the role of the gut-brain axis is a significant factor in the risk for numerous health disorders throughout life, and it can have substantial implications on your body-brain health as you age. For example, numerous studies have ex...2022-05-2929 minThe Alzheimer’s Solution Revolution PodcastThe Role of Cardiometabolic Disease and Insulin Resistance in Vascular Dementia, Type 3 Diabetes and Alzheimer’s diseaseToday in episode # 8 I'll be reviewing the role of hypertension, obesity, type 2 diabetes and heart disease (cardiometabolic disease), and insulin resistance in your risk for late onset Alzheimer's disease.The metabolic and biochemical pathways by which cardiometabolic disease increases the risk for dementia and Alzheimer's later life is the central theme in my book: The Diabetic Brain in Alzheimer's Disease.The book thoroughly describes how and why the most prevalent age-related disorders of our time, put your brain and you at great risk for either vascular dementia, type 3 diabetes and Alzheimer's...2022-05-1726 minThe Alzheimer’s Solution Revolution PodcastGenetic Variants in the Risk for Late-onset Alzheimer’s Disease—ApoE4 and BeyondHow does you unique genome increase the risk for Alzheimer's disease as you age?In todays episode—#7, I’ll be giving a comprehensive overview on the APOE gene, the ApoE4 genetic variant, and other genes and their genetic variants linked to the risk for late-onset Alzheimer's Disease (LOAD), and how, when, and why Alzheimer's takes root in certain individuals that are carriers of these genes and the variants associated with them.While the ApoE4 genetic risk variant is widely recognized as a risk factor for LOAD, how ApoE4 contributes to t...2022-05-0736 minThe Alzheimer’s Solution Revolution PodcastHow Early in Life Can You Begin to Assess AND Track Your Risk for Late-Onset Alzheimer’s Disease?How early in your lifespan you can start to assess and track for specific biomarkers that are linked to the risk and earliest stages of late-onset Alzheimer's disease (LOAD), and have you given that much thought?In fact, there has been a significant shift in the progressive medical and research community over the last ten years in the understanding that you really have to start looking at your risk factors for LOAD earlier in life—at least by midlife, By midlife the brain damage associated with LOAD begins to hit a pivotal crisis point in ter...2022-04-2427 minThe Alzheimer’s Solution Revolution PodcastThe Role of Tau Protein and Tau Tangles in the Progression and Development of Alzheimer’s DiseaseIn the fifth episode of The Alzheimer’s Solutions Revolution podcast with Ralph Sanchez, I talk with my co-host Susan Brender, as we continue with our special podcast series called Think Ahead. In this week’s episode, I'll provide an overview on the role of tau protein and neurofibrillary tangles (tau tangles) in the progression and development of late-onset Alzheimer's disease (LOAD).The toxic accumulation of tau tangles in brain cells (neurons) are one of the two hallmark lesions associated with Alzheimer's disease (AD). The aggregation of beta-amyloid peptides (protein) into amyl...2022-04-1719 minThe Alzheimer’s Solution Revolution PodcastThe Role of Beta-Amyloid Protein in the Progression and Development of Alzheimer’s Disease that Spans DecadesIn this Alzheimer's Solution Revolution episode #4, I’ll give an overview of episode #3, and I’ll provide several key insights about a protein that is associated with the pathology of Alzheimer’s disease—beta-amyloid protein, which forms the proverbial amyloid plaque that is often cited as a principal lesion of the disease process.Additionally, in this Think Ahead podcast, I pick up where we left off on the last episode (#3) with regard to the genesis of Alzheimer’s, disease in the brain, and the role of beta-amyloid protein aggregates in the progression of Alzheimer’s disease in a...2022-04-1024 min
The Ralph Moore PodcastLuis Sanchez - Simple Church Collective (Part 2 of 2)The Simple Church Collective began in 2019 as a prevailing model church startup led by Luis and Melissa Sánchez. As COVID-19 changed the world the church changed with it. Luis and Melissa began to wrestle with the question, "What is a church in its most basic form?" By the summer of 2020 Luis and Melissa were convinced that biblically faithful churches in their most basic expressions are communities that meet certain irreducible minimums. There are just four of these, but an expanded value-set includes Jesus as the center, Spirit-led prayer, hospitality, generosity, compassion, social responsibility and eng...2022-04-0821 minThe Alzheimer’s Solution Revolution PodcastInsights Into the Genesis of Early-Onset and Late-Onset Alzheimer’s Disease in AgingIn this 3rd episode of The Alzheimer’s Solutions Revolution Podcast, I, Ralph Sanchez, talk with my good friend and co-host Susan Brender, as we begin this special podcast series designated as the Think Ahead podcast series. In the Think Ahead series, which will be published here over the coming weeks, I'll provide an extensive overview on the numerous risk factors associated with late-onset Alzheimer’s disease (LOAD), and I expand on the research that sheds light on how you can modify and reduce your risk for LOAD and dementia as you age. 2022-04-0327 min
The Ralph Moore PodcastLuis Sanchez - Simple Church CollectiveThe Simple Church Collective began in 2019 as a prevailing model church startup led by Luis and Melissa Sánchez.As COVID-19 changed the world the church changed with it. Luis and Melissa began to wrestle with the question, "What is a church in its most basic form?" By the summer of 2020 Luis and Melissa were convinced that biblically faithful churches in their most basic expressions are communities that meet certain irreducible minimums. There are just four of these, but an expanded value-set includes Jesus as the center, Spirit-led prayer, hospitality, generosity, compassion, social responsibility and eng...2022-04-0121 minThe Alzheimer’s Solution Revolution PodcastCan a Basic Multivitamin and Mineral Supplement Reduce Your Risk for Cognitive Decline and Dementia as You Age?Should you supplement with a basic MVM to sustain a healthy brain in aging? Has any physician or practitioner emphasized just how important a MVM supplement might be for your brain and heart as you get older?Well, as promised on my welcome episode last week, I'll be expanding on a study and recent research with regard to the supplementation with vitamins, minerals and certain nutrients found in foods, and it's role in the heart-brain axis in this episode of The Alzheimer's Solution Revolution Podcast.The study that I will be referring to today looked...2022-03-2823 minThe Alzheimer’s Solution Revolution PodcastWelcome to The Alzheimer’s Solution Revolution Podcast!Welcome!Indeed, this is the inaugural episode of the The Alzheimer's Solution Revolution Podcast!This is your host. Ralph Sanchez, and I am grateful that you are reading and/or listening in to what this podcast will bringing to you on a weekly basis.The purpose of this welcome edition is to share a little about me and my experience and background in health care and medicine that emphasized a progressive paradigm and model of healthcare termed functional medicine. Essentially, the overall scope of this podcast will t...2022-03-1709 min
The Official Jets PodcastThe Exchange Podcast with Nick Mangold & Mark Sanchez | Ralph Macchio (S1EP3)Hosts Mark Sanchez and Nick Mangold get to meet their hero, Ralph Macchio, better known as The Karate Kid. A huge Jets fan from childhood, Macchio and the guys discuss growing up a Jets fan, Sanchez's favorite Karate Kid filming location, and Macchio’s snub of Mangold during a 2014 interview. The group also discusses a cameo appearance for Sanchez and Mangold in an upcoming season of Cobra Kai.2022-01-1836 min