RevGenetics - Podcast Details

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Supplements Podcast By RevGeneticsRevGenetics Unpacks Advanced NAD Supplement with NNMT Inhibitor & Probiotics - Podcast 027In this RevGenetics podcast, Les and Amy introduce the new advanced NAD supplement with a special delivery system in BioVXR capsules. The formula addresses challenges with NAD breakdown by NNMT enzyme, using NAD shield with an NNMT inhibitor and low-dose NAD precursor strategy. Ingredients include NAD precursor, trans resveratrol for antioxidant properties, and NNMT inhibitor from vanilla beans. Probiotics Bifidobacterium infantis and Lactobacillus salivarius support gut health for better nutrient absorption. This targeted approach offers a promising solution for boosting NAD levels and promoting healthy aging. Study: https://cdn.shopify.com/s/files/1/2088/8715/files/Eurofins_-_Capsule_Tests.png...2024-12-1113 min

Supplements Podcast By RevGeneticsCES Electro Stimulation - 11-20-2024 Studies Podcast 026 In this podcast by RebGenetics, we explore peripheral nerve regeneration. When nerves are damaged, they can regrow, but the process is slow and doesn't always lead to full recovery. Wallarian Degeneration breaks down the injured nerve, paving the way for regrowth. Schwann cells act as cleanup crew and guide axon regrowth. Time and distance affect recovery, making it a race against time. Electrical stimulation, like post-operative and conditioning stimulation, can aid in nerve regeneration by providing guidance and support. Overall, understanding the complexities of nerve regeneration can help improve recovery outcomes. 2024-12-1111 min

Supplements Podcast By RevGeneticsExciting NMN Research: Boosting NAD+ for Health Benefits, Alzheimer's Potential - Podcast 025In this podcast, we explore the groundbreaking potential of **NMN (Nicotinamide Mononucleotide)**, a crucial molecule for **NAD+ production** in the body. As NAD+ levels naturally decline with age, NMN emerges as a promising solution to combat age-related health issues. Recent studies, including a groundbreaking **Nature study**, highlight NMN's ability to protect neurons and synapses critical for memory and cognition, offering hope in the fight against **Alzheimer's disease**. By activating the **ATF4 pathway**, NMN helps clear harmful proteins linked to Alzheimer's, showcasing its neuroprotective benefits. NMN is also gaining attention for its role in **fertility**. Research suggests NMN supports mitochondrial...2024-11-2012 min

Supplements Podcast By RevGeneticsSpermidine: Boosting Longevity and Fertility in Aging Cells - Podcast 023Discover the incredible potential of spermidine for longevity and reproductive health in this podcast! Spermidine, a natural polyamine found in all living organisms, plays a vital role in cellular health. Cutting-edge research reveals that spermidine supplementation can help combat cellular deterioration, enhance **oocyte quality** in aging females, and even slow down the aging process. Exciting studies also suggest that spermidine may improve fertility by boosting sperm binding and increasing fertilization rates in aged oocytes, offering hope for couples dealing with age-related fertility challenges. Dive in as we explore how spermidine is transforming the fields...2024-11-1817 min

Supplements Podcast By RevGeneticsResveratrol: Potential COVID & Parkinson's Treatment Unpacked in Research Papers - Podcast 023In today's podcast, we explore the exciting potential of resveratrol in addressing COVID-19 and Parkinson's disease. Researchers have discovered that resveratrol targets critical processes in lung damage, offering hope for reducing infection and scarring. Using advanced virtual models, they’ve observed how resveratrol interacts at a molecular level, suggesting promising therapeutic effects. For Parkinson's disease, cutting-edge science is investigating nanoparticle delivery systems to optimize resveratrol's benefits, paving the way for groundbreaking treatments. Dive into the latest research and learn how this natural compound is shaping the future of medicine. **Referenced Studies:** 🔗 [De Gruyter Study](https://www.degruyter.com/document/doi/1...2024-11-1509 min

Supplements Podcast By RevGeneticsLeaky Gut Aging - Digestive Enzymes Escape, Collagen Damage Revealed! - Podcast 022Can eating make us age faster? 🧐 In this video, we take a fascinating deep dive into the science of aging and digestion. Research suggests that as we age, digestive enzymes like trypsin and elastase may leak out of the gut, wreaking havoc on our organs and collagen. These enzymes, designed to break down food, can mistakenly start breaking down other parts of our bodies, potentially contributing to wrinkles, sagging skin, and other aging effects. A recent study found that older rats had higher levels of these enzymes, leading to significant collagen damage in various organs. The connection bet...2024-10-2209 min

Supplements Podcast By RevGeneticsSpermidine vs MRSA - Spermidine Boosts Immunity Against MRSA Infections - Podcast 021 In this podcast, researchers explore the link between gut health and fighting off MRSA infections. They found that antibiotics disrupting gut bacteria made mice more susceptible to severe MRSA infections. However, fecal transplants from healthy mice improved infections drastically. The key molecule identified was spermidine, produced by gut bacteria. Mice with higher spermidine levels showed improved survival rates and reduced infection severity when infected with MRSA. Spermidine seemed to boost the immune system's response to the infection. This research highlights the importance of gut health in combating antibiotic-resistant superbugs like MRSA. Study: https://pubs.acs.org/doi/epdf/10.1021/acsinfecdis.3...2024-10-1911 min

Supplements Podcast By RevGeneticsNew Cancer Research: Unveiling the Mitochondrial Stem Cell Connection (MSCC) Treatment Podcast 020In this Podcast, we explore cutting-edge cancer research on the mitochondrial stem cell connection (MSCC). Published in September 2024, this study challenges traditional views by focusing on cellular energy crises. The MSCC theory suggests that malfunctioning mitochondria in stem cells can trigger tumor formation, leading to aggressive cancer growth. Cancer cells, desperate for energy, become "sugar addicts," relying on glucose and glutamine for fuel. This research highlights seven key points, emphasizing the importance of understanding how cellular energy processes impact cancer development. Stay tuned for more insights into this fascinating and groundbreaking study that provides dose and information on Intravenous...2024-10-1419 min

Supplements Podcast By RevGeneticsScientists explore Aging and COVID severity and how zombie cells impact infection. Podcast 019 Scientists are exploring how aging impacts COVID severity, focusing on lung aging and cellular senescence. As we age, our lungs lose efficiency in repair mechanisms, like basal cells and cilia, making us more vulnerable to infections. Cellular senescence leads to zombie cells releasing inflammatory molecules, creating an inflammatory soup that affects healthy cells. This process, known as SASAP, worsens with SARS-CoV-2 infection, potentially explaining why COVID hits some harder than others. By understanding these aging-related factors, researchers hope to develop new strategies like Senolytics to combat COVID and improve outcomes. Study: https://link.springer.com/article/10.1186/s13619-024-00201...2024-10-1009 min

Supplements Podcast By RevGeneticsChocolate Flavanols and Skin Protection: Study on Sun Impact. Podcast 018 In this podcast, we explore a study on whether chocolate high in flavanols can protect skin from the sun. Flavanols are antioxidants found in cocoa beans, fruits, and vegetables. The study involved women aged 20-65 consuming chocolate daily for 12 weeks. Researchers measured skin protection using the minimal erythema dose (MED), which indicates sun sensitivity. By tracking MED changes, they assessed the impact of chocolate consumption on skin reaction to UV radiation. The study aimed to determine if flavanols in chocolate could provide additional antioxidant protection for the skin. Stay tuned to learn more about the fascinating findings! Study: https...2024-10-0910 min

Supplements Podcast By RevGeneticsIL-11 Inhibition Boosts Lifespan: Anti-Aging Breakthrough! Podcast 017 In this podcast, we explore groundbreaking research on inhibiting IL-11 signaling to extend health span and lifespan. IL-11, a key player in inflammation, may hold the key to anti-aging therapies. By studying mice, researchers found that blocking IL-11 activity led to significant lifespan extension, up to 20%. IL-11 acts as a spark, triggering molecules like ERK, AMPK, and MTORC1, impacting cell repair, energy use, and nutrient processing. This discovery offers promising insights into the mechanisms of aging and potential interventions for extending human lifespan significantly. Study: https://www.nature.com/articles/s41586-024-07701-9 While we don't see anything...2024-10-0807 min

Supplements Podcast By RevGeneticsGoldenrod Extract Shows Anti-Aging Potential by Preserving Youthful Skin Cells: Podcast 016 In the video, researchers delve into the science of aging and skincare, focusing on a plant extract from Goldenrod that shows promising anti-aging properties. The extract, derived from Solidago vergaria subspecies alpestris, was found to slow down the aging process in skin cells called fibroblasts. It helps preserve youthful fibroblasts by delaying a transition that occurs with age. Additionally, the extract reduces the senescence-associated secretory phenotype, a process that occurs when cells age. This research offers a deeper understanding of how skin cells age and the potential benefits of using Goldenrod extract for maintaining youthful skin. Study: https://www...2024-10-0708 min

Supplements Podcast By RevGeneticsUnlocking Brain Boosting Potential with Polydatin (M98 Resveratrol) in Down Syndrome. Podcast 015Polydatin vs Downs Syndrome? In today's deep dive, we explore groundbreaking research on improving brain development in individuals with Down syndrome. The study focuses on neurogenesis and dendritogenesis, crucial processes for cognitive function. Disruptions in these processes can impact learning and memory. The potential hero is polydatin (aka M98 Resveratrol), a polyphenol found in grapes. Polyphenols act as brain guardians, protecting cells and stimulating neurogenesis. They also enhance synaptic plasticity, the brain's ability to rewire itself. This research offers hope for enhancing brain function in individuals with Down syndrome using a natural compound. Stay tuned for more exciting updates...2024-10-0410 min

Supplements Podcast By RevGeneticsGreen Tea EGCG vs. Pesticides: EGCG Saves the Day in Zebrafish Study. Podcast 014In this video, we explore the potential of green tea, specifically EGCG, to combat the harmful effects of organophosphate pesticides (OPs). OPs disrupt the crucial enzyme ACE, leading to neurological issues and long-term risks like Alzheimer's. Researchers conducted a study using zebrafish, finding that EGCG reversed the enzyme inhibition caused by OPs, increasing enzyme activity by over 50%. EGCG competes with OPs for binding sites on the ACE enzyme, acting as a protective shield. This research highlights the promising protective effects of EGCG from green tea against pesticide exposure, offering a potential solution to mitigate health risks. Studies: https://journalofethnicfoods...2024-10-0308 min

Supplements Podcast By RevGeneticsBreakthrough in Pregnancy Health: Metabolomics Reveals Early Warning Signs for issues Podcast 013Pregnancy Health with Aminos and Polyamines. In this video, we explore groundbreaking research from Russia on pregnancy health, focusing on fetal growth restriction (FGR) and preeclampsia. By delving into metabolomics, researchers are deciphering molecular clues in pregnant women's blood to detect issues early. They are honing in on amino acids and polyamines, essential for cellular function. Findings show that women with FGR and preeclampsia had distinct amino acid and polyamine profiles compared to those with healthy pregnancies. Maintaining the right balance of amino acids is crucial, with arginine and lysine playing key roles in FGR. This innovative approach offers...2024-10-0311 min

Supplements Podcast By RevGeneticsStudy reveals link between epigenetic noise and mammal lifespan, hinting at longevity Podcast 012In a recent study from Spain, researchers explored the concept of epigenetic noise and its impact on lifespan in mammals. Epigenetics is like software updates for your DNA, influenced by your environment and experiences. The study found that mammals with longer lifespans accumulate epigenetic noise at a slower rate than those with shorter lifespans. This noise can be likened to chaotic scribbles on an instruction manual, making it harder for cells to read genetic instructions accurately. By understanding and managing epigenetic noise, we may uncover insights into aging and potentially extend lifespan. Study: https://www.biorxiv.org/content/10.1101/2024.09.06.611669v1 ...2024-10-0307 min

Supplements Podcast By RevGeneticsSerine: Key to Eye Health & Vision Problems Prevention - New Research Reveals Insights Podcast 011In this video, we learn about the importance of the amino acid serine for eye health, particularly in preventing and treating vision problems like macular telangiectasia (MacTel). Research published in Cell Metabolism explores the connection between serine and the retina, emphasizing its role in providing energy and protecting cells. The retina has three ways of obtaining serine: through the bloodstream, local production from glucose, and a backup system. This highlights the importance of a balanced diet and efficient absorption for maintaining healthy retinas. Understanding these mechanisms could lead to new insights in eye health and potential treatments for degenerative...2024-10-0311 min

Supplements Podcast By RevGeneticsBrain DNA Is Different! Unraveling Genomic Mosaicism in the Brain: Podcast 010In this video, we explore the mind-bending concept of genomic mosaicism, revealing that our brain cells are not genetic clones as previously thought. Each brain cell has its own unique genetic story due to tiny variations in DNA. This phenomenon, known as genomic mosaicism, is surprisingly common and occurs after fertilization, leading to different levels of genetic variation in the brain. This hidden layer of complexity challenges the idea of one genome per person, highlighting the dynamic nature of our DNA throughout life. Dive into the fascinating world of genomic mosaicism and discover the intricate genetic landscape of the...2024-10-0312 min

Supplements Podcast By RevGeneticsEGCG in Green Tea: Brain Protection & Virus Blocker - Fascinating Research Summary Podcast 009EGCG September 2024 studies. In this podcast, we explore the potential benefits of EGCG, a compound found in green tea. Research on rats showed that EGCG significantly reduced brain damage caused by high histamine levels, improving behavior and cell health. While promising, these findings are preliminary and more research on humans is needed. Another study suggested EGCG could block the entry of HPV into cells, but this was observed in a lab setting, not in humans drinking green tea. The power of natural compounds like EGCG is intriguing, but further studies are required to fully understand its potential health benefits. ...2024-10-0313 min

Supplements Podcast By RevGeneticsRevitalizing Liver Health with Turmeric Metabolite TetrahydroCurcumin (TetraCurcumin) Podcast 008Tetrahydrocurcumin (TetraCurcumin): In this podcast, we explore exciting research on liver health using turmeric's metabolite, tetrahydrocurcumin (THC), as a potential treatment for non-alcoholic fatty liver disease (NAFLD) and NASH. This is NOT Tetrahydrocannabinol from cannabis, this is TetraCurcumin from Turmeric. Recent studies in rats show THC's ability to improve liver health by reducing fat buildup, inflammation, and oxidative stress. THC may enhance lipophagy, the cellular cleaning process for fat removal, by acting on the MTORC1-TFAB pathway. This pathway regulates energy conservation in cells, potentially aiding in clearing fat droplets. Consult your doctor before...2024-10-0312 min

Supplements Podcast By RevGeneticsCan TA65 Supplement Lengthen Telomeres? Study Reveals Surprising Results in Humans. Podcast 007The TA-65 Human Study. In this podcast, we delve into the fascinating world of telomeres, the protective caps at the ends of our DNA strands that impact aging. A study published in 2016 explored the effects of the supplement TA65 on telomere length in humans. The research, a randomized double-blind placebo-controlled trial, revealed that a low dose of TA65 led to significant telomere lengthening, particularly in the shortest telomeres associated with age-related decline. Surprisingly, a higher dose did not have the same effect, highlighting the complexity of dosage in the body. While intriguing, it's important to note that study participants...2024-10-0308 min

Supplements Podcast By RevGeneticsResveratrol Research: Unpacking Absorption and Metabolism for Health Benefits Podcast 006Resveratrol research today. In this podcast, we explore the fascinating world of resveratrol research. Despite its low absorption rate of less than 1%, resveratrol transforms into active metabolites with biological benefits. The concept of xenohermesis suggests our bodies respond to plant-derived chemical signals. While the hype around resveratrol may be complex, its potential benefits are not unfounded. Studies on PCOS, absorption, and autophagy reveal promising aspects of resveratrol's impact. So, don't give up on the red wine dream just yet - there's more to this compound than meets the eye. Join us for a deep dive into the world of...2024-10-0324 min

Supplements Podcast By RevGeneticsFisetin: Key to Slowing Aging by Targeting Senescent Cells in Mice - Study Podcast 005In this podcast, researchers discuss the potential of Fisetin, found in strawberries, as a key ingredient in slowing down aging by targeting cellular senescence. Senescent cells, which stop dividing and release inflammatory signals, contribute to aging-related issues. The study, published in Biomedicine, suggests Fisetin as a potent senolytic, cleaning up these problematic cells. In vitro experiments showed Fisetin's effectiveness in eliminating senescent cells compared to other flavonoids. Further tests on mice with progeroid syndrome supported these findings. The research aims to find safer and more effective senolytics for combating age-related diseases. You would need to eat approximately 6.9 pounds of...2024-10-0309 min

Supplements Podcast By RevGeneticsUnveiling NMN: Studies Show Potential Benefits for Aging, Heart, and Bone Health Podcast 004NMN & Skeletal Stem Cells. In this podcast, we explore the buzz around NMN supplements. Recent studies reveal the truth behind the labels, with some products lacking detectable NMN while others exceed claims. Quality control is a major concern, emphasizing the need for better regulation. NMN shows promise in protecting the heart under simulated weightlessness and speeding up bone fracture healing by encouraging stem cell multiplication. Its influence on NAD levels and gene expression raises questions about its broader impact on aging organs. The quest for trustworthy sources and understanding NMN's potential benefits underscores the importance of supplement quality and...2024-10-0309 min

Supplements Podcast By RevGeneticsUnlocking the Power of EGCG: Managing Hypertension with Science-backed Benefits - Podecast 003The Power of EGCG: Unlocking Green Tea's Health Benefits for Hypertension In this episode, we explore the remarkable benefits of EGCG, a powerful compound derived from green tea. With growing research backing its ability to manage hypertension, EGCG shows promise in improving cardiovascular health by enhancing blood vessel flexibility, promoting better blood flow, and reducing strain on the heart. Studies on animal models, such as rats, have demonstrated that EGCG may slow the progression of hypertension. What's even more fascinating is how EGCG interacts with the Renin-Angiotensin-Aldosterone System (RAAS), the body's hormonal system that regulates blood pressure. Acting like...2024-10-0308 min

Supplements Podcast By RevGeneticsUnlocking Longevity Secrets: Spermidine in Foods for Healthier Aging. Supplements Podcast 002Spermidine and longevity. Unlocking Longevity Secrets: Spermidine in Foods for Healthier Aging. In this podcast, we explore the quest for longevity through research on foods and compounds. A recent study tested formulations on microscopic worms, extending their lifespan significantly, with one outperforming resveratrol. The key ingredient in these formulations is spermidine, found in foods like white button mushrooms. Spermidine plays a crucial role in autophagy, the cell's cleanup process, helping to remove damaged components and promote cell efficiency. This research sheds light on potential benefits for human longevity through dietary sources of spermidine. Stay tuned...2024-10-0306 min

Supplements Podcast By RevGeneticsCurcumin: Brain Protector or Cure? Neuroprotective Power of Turmeric's Active Compound. Podcast 001Super Curcumin! What does Curcumin do exactly? In this video, we explore the potential of curcumin, an active compound in turmeric, to combat neurodegenerative diseases like Alzheimer's and Parkinson's. Curcumin shows promise as a neuroprotective agent, shielding the brain from damage by acting as an anti-inflammatory, antioxidant, and potentially an anti-amyloid agent. However, a major challenge is the low bioavailability of curcumin in the body, limiting its effectiveness. Researchers are investigating nanotechnology to enhance curcumin delivery and maximize its therapeutic benefits. Stay tuned to learn more about this exciting avenue in the fight against brain diseases! RevGenetics...2024-09-2716 min