Shows
Surgical Pioneering Podcast"MitraClip Procedure Overview"Authored by Dr. Reza Lankarani, General Surgeon MitraClip™ is a minimally invasive transcatheter edge-to-edge repair (TEER) device designed to treat mitral regurgitation (MR), a condition where the mitral valve fails to close properly, causing blood to leak backward into the heart. Inspired by the Alfieri surgical technique, which sutures the valve leaflets to create a double orifice, the MitraClip uses a small metal clip to grasp and coapt the leaflets, reducing regurgitation . It is the first FDA-approved transcatheter mitral valve repair therapy and has been used in over 200,000 patients globally.------------------------------------------------------------Indications: - Primary (Degenerative) MR: For patients at prohibitive surgical ri...2025-07-1921 min
Surgical Pioneering Podcast"Association Between Triglyceride-Glucose Index and Breast Cancer: A Systematic Review and Meta-Analysis"Reviewed by Reza Lankarani M.D ------------------------------------------------------------Zooravar et al., Cancer Reports (2025)https://doi.org/10.1002/cnr2.70194------------------------------------------------------------This academic article presents a systematic review and meta-analysis examining the Triglyceride-Glucose (TyG) index in relation to breast cancer. It evaluates the TyG index as a potential indicator for breast cancer risk, progression, and its ability to differentiate between malignant and benign breast lesions. While cohort studies did not establish a strong predictive link for initial breast cancer development, case-control and cross-sectional studies suggested a significant association between elevated TyG index and...2025-07-1812 min
Surgical Pioneering Podcast"Association Between Triglyceride-Glucose Index and Breast Cancer: A Systematic Review and Meta-Analysis"Reviewed by Reza Lankarani M.D ------------------------------------------------------------Zooravar et al., Cancer Reports (2025)https://doi.org/10.1002/cnr2.70194------------------------------------------------------------This academic article presents a systematic review and meta-analysis examining the Triglyceride-Glucose (TyG) index in relation to breast cancer. It evaluates the TyG index as a potential indicator for breast cancer risk, progression, and its ability to differentiate between malignant and benign breast lesions. While cohort studies did not establish a strong predictive link for initial breast cancer development, case-control and cross-sectional studies suggested a significant association between elevated TyG index and increased risk. The research highlights the TyG index's utility in distinguishing malignant from...2025-07-1812 min
Surgical Pioneering Podcast"Burns and Mental Health: A Matched Cohort Study"Reviewed by Reza Lankarani M.D ------------------------------------------------------------ Published online June 2025DOI: 10.1097/SLA.0000000000006270Annals of Surgery------------------------------------------------------------ This large-scale matched cohort study investigates the long-term association between burn injuries and mental health hospitalizations over 33 years. Analyzing 23,726 burn patients and 223,626 controls from Quebec, Canada, the study found that burn survivors had a 1.76-fold increased risk of mental health hospitalization compared to controls, with risks persisting up to 30 years post-injury. Severe burns (≥50% body surface area, third-degree burns, skin graft requirements) were linked to higher risks (HR: 2.00–3.29). Notably, burn pati...2025-07-1602 min
Surgical Pioneering Podcast"Burns and Mental Health: A Matched Cohort Study"Reviewed by Reza Lankarani M.D ------------------------------------------------------------ Published online June 2025DOI: 10.1097/SLA.0000000000006270Annals of Surgery------------------------------------------------------------ This large-scale matched cohort study investigates the long-term association between burn injuries and mental health hospitalizations over 33 years. Analyzing 23,726 burn patients and 223,626 controls from Quebec, Canada, the study found that burn survivors had a 1.76-fold increased risk of mental health hospitalization compared to controls, with risks persisting up to 30 years post-injury. Severe burns (≥50% body surface area, third-degree burns, skin graft requirements) were linked to higher risks (HR: 2.00–3.29). Notably, burn patients exhibited elevated risks for eating disorders (HR: 3.14), substance use disorders (HR: 2.27), and suicide attempts (HR: 2.42), part...2025-07-1602 min
Surgical Pioneering Podcast"Comparison Between Endovascular and Surgical Treatment of Acute Arterial Occlusive Mesenteric Ischemia"Reviewed by Reza Lankarani MD -------------------------World Journal of Emergency Surgeryhttps:/doi.org/10.1186/s13017-025-00616-4This prospective observational substudy of the AMESI cohort provides valuable insights into the complex management of acute arterial occlusive mesenteric ischemia (AMI), specifically superior mesenteric artery (SMA) occlusion. Crucially, the authors rigorously account for baseline severity of illness (APACHE II, SOFA, lactate, vasopressor/ventilator needs), a major confounder often inadequately addressed in prior literature. Their sophisticated statistical approach, including multivariable logistic regression adjusted for key severity markers, robustly demonstrates...2025-07-1502 minSurgical Pioneering Podcast"Comparison Between Endovascular and Surgical Treatment of Acute Arterial Occlusive Mesenteric Ischemia"Reviewed by Reza Lankarani MD -------------------------World Journal of Emergency Surgeryhttps:/doi.org/10.1186/s13017-025-00616-4This prospective observational substudy of the AMESI cohort provides valuable insights into the complex management of acute arterial occlusive mesenteric ischemia (AMI), specifically superior mesenteric artery (SMA) occlusion. Crucially, the authors rigorously account for baseline severity of illness (APACHE II, SOFA, lactate, vasopressor/ventilator needs), a major confounder often inadequately addressed in prior literature. Their sophisticated statistical approach, including multivariable logistic regression adjusted for key severity markers, robustly demonstrates that the apparent mortality benefit of endovascular therapy in unadjusted analysis (15.7% vs. 45.8%) is largely attributable...2025-07-1502 min
Surgical Pioneering Podcast"Vagilangelo, Innovation or Exploitation in Women’s Health Deep Dive Podcast"The provided sources, primarily critiques from an OBGYN and health disparities researcher, Dr. Reza Lankarani, highlight significant concerns regarding the Vagilangelo® procedure and the broader landscape of cosmetic gynecology, particularly in the context of medical tourism and training in Arab countries. The central theme revolves around the tension between profit-driven healthcare and patient safety, arguing that the commercialization of uncertainty in women's health is exploitation, not innovation.1. The Vagilangelo® Procedure: Unsubstantiated Claims and Evidence DeficitThe Vagilangelo® procedure, marketed as a revolutionary vaginal rejuvenation technique, aims to restore "natural vaginal angulation" thr...2025-07-1314 min
Surgical Pioneering Podcast"Vagilangelo, Innovation or Exploitation in Women’s Health Deep Dive Podcast"The provided sources, primarily critiques from an OBGYN and health disparities researcher, Dr. Reza Lankarani, highlight significant concerns regarding the Vagilangelo® procedure and the broader landscape of cosmetic gynecology, particularly in the context of medical tourism and training in Arab countries. The central theme revolves around the tension between profit-driven healthcare and patient safety, arguing that the commercialization of uncertainty in women's health is exploitation, not innovation.1. The Vagilangelo® Procedure: Unsubstantiated Claims and Evidence DeficitThe Vagilangelo® procedure, marketed as a revolutionary vaginal rejuvenation technique, aims to restore "natural vaginal angulation" through internal suturing and platelet-rich plasma (PRP) injections. However, the sou...2025-07-1314 min
Surgical Pioneering PodcastVagilangelo, Innovation or Exploitation in Women’s Health?Authored by Reza Lankarani MD Section 1: IntroductionCosmetic gynecology is a rapidly growing field, fueled by technological advances and increasing societal interest in aesthetic and functional modifications of female genital anatomy. Among these innovations, Vagilangelo® is heavily marketed as a revolutionary, minimally invasive vaginal rejuvenation technique promising to restore the "natural vaginal angle" disrupted by childbirth or aging, with purported benefits in sexual satisfaction and sensitivity.However, beneath its glossy promotional veneer lies a complex web of scientific uncertainties, ethical dilemmas, and health equity challenges. Today, we will dissect t...2025-07-1102 min
Surgical Pioneering PodcastVagilangelo, Innovation or Exploitation in Women’s Health?Authored by Reza Lankarani MD Section 1: IntroductionCosmetic gynecology is a rapidly growing field, fueled by technological advances and increasing societal interest in aesthetic and functional modifications of female genital anatomy. Among these innovations, Vagilangelo® is heavily marketed as a revolutionary, minimally invasive vaginal rejuvenation technique promising to restore the "natural vaginal angle" disrupted by childbirth or aging, with purported benefits in sexual satisfaction and sensitivity.However, beneath its glossy promotional veneer lies a complex web of scientific uncertainties, ethical dilemmas, and health equity challenges. Today, we will dissect these layers with academic rigor and clinical insight to provide you, our l...2025-07-1102 min
Surgical Pioneering PodcastGLP-1 Agonists Versus Bariatric Surgery: A Paradigm Shift?GLP-1 Agonists Versus Bariatric Surgery: A Paradigm Shift?1.1. Host: Obesity and diabetes management are seeing a seismic shift, Dr. Lankarani, with GLP-1 agonists like semaglutide making headlines. Is metabolic surgery becoming obsolete, or do these drugs complement existing surgical interventions?1.2. Guest: It's a critical juncture. While GLP-1 drugs offer noninvasiveness and 15–22% weight loss, bariatric surgery still outperforms in durability—delivering over 25% weight loss and diabetes remission in 80% of patients, as shown in STAMPEDE trial's 10-year data, which all these databases gatheredby by Dr Reza Lankarani, General Surgeon and Surgical Innovation Lead, Curator and Founder of Surgical Pioneering Newsletter and Podcast Seri...2025-07-0801 min
Surgical Pioneering PodcastGLP-1 Agonists Versus Bariatric Surgery: A Paradigm Shift?GLP-1 Agonists Versus Bariatric Surgery: A Paradigm Shift?1.1. Host: Obesity and diabetes management are seeing a seismic shift, Dr. Lankarani, with GLP-1 agonists like semaglutide making headlines. Is metabolic surgery becoming obsolete, or do these drugs complement existing surgical interventions?1.2. Guest: It's a critical juncture. While GLP-1 drugs offer noninvasiveness and 15–22% weight loss, bariatric surgery still outperforms in durability—delivering over 25% weight loss and diabetes remission in 80% of patients, as shown in STAMPEDE trial's 10-year data, which all these databases gatheredby by Dr Reza Lankarani, General Surgeon and Surgical Innovation Lead, Curator and Founder of Surg...2025-07-0801 min
Surgical Pioneering Podcast"Top 5 Controversies in General Surgery for 2024–2025"Authored by Reza Lankarani, M.D General surgery faces intense debates for 2024–2025, including GLP1 agonists vs. bariatric surgery, bridging anticoagulation in urgent cancer surgery, timing of hip fracture repair in heart failure patients, robotic vs. laparoscopic surgery costs and benefits, and opioid-sparing pain protocols. Key issues revolve around clinical outcomes, evolving technology, cost-effectiveness, patient safety, and ethical challenges in modern surgical care. 1. GLP-1 Agonists Versus Bariatric Surgery: A Paradigm Shift? 1.1. Host: Obesity and diabetes management are seeing a seismic shift, Dr. Lankarani, with GLP-1 agonists like semaglutide making headlines. Is...2025-07-0708 min
Surgical Pioneering Podcast"Top 5 Controversies in General Surgery for 2024–2025"Authored by Reza Lankarani, M.D General surgery faces intense debates for 2024–2025, including GLP1 agonists vs. bariatric surgery, bridging anticoagulation in urgent cancer surgery, timing of hip fracture repair in heart failure patients, robotic vs. laparoscopic surgery costs and benefits, and opioid-sparing pain protocols. Key issues revolve around clinical outcomes, evolving technology, cost-effectiveness, patient safety, and ethical challenges in modern surgical care. 1. GLP-1 Agonists Versus Bariatric Surgery: A Paradigm Shift? 1.1. Host: Obesity and diabetes management are seeing a seismic shift, Dr. Lankarani, with GLP-1 agonists like semaglutide making headlines. Is metabolic surgery becoming obsolete, or do these drugs complement existing su...2025-07-0708 min
Surgical Pioneering Podcast"Effects of the lavage through fistula in treatment of spontaneous esophageal rupture by combined thoracoscopic and gastroscopic management""Effects of the lavage through fistula in treatment of spontaneous esophageal rupture by combined thoracoscop and gastroscop "Reviewed by Reza Lankarani M.D--------------------------------World Journal of Emergency SurgeryPublished: 07 June 2025https://doi.org/10.1186/s13017-025-00630-6--------------------------------This retrospective study (2014-2024, n = 24) evaluates a novel lavage-drainage technique for spontaneous esophageal rupture (SER/Boehhaave's syndrome).Patients undergoing VATS debridement/drainage were divided into:1. Lavage-Drainage Group (n = 11): Gastroscopically guided placement of a nasogastric tube through the esophageal fistula for...2025-07-0602 minSurgical Pioneering Podcast"Effects of the lavage through fistula in treatment of spontaneous esophageal rupture by combined thoracoscopic and gastroscopic management""Effects of the lavage through fistula in treatment of spontaneous esophageal rupture by combined thoracoscop and gastroscop "Reviewed by Reza Lankarani M.D--------------------------------World Journal of Emergency SurgeryPublished: 07 June 2025https://doi.org/10.1186/s13017-025-00630-6--------------------------------This retrospective study (2014-2024, n = 24) evaluates a novel lavage-drainage technique for spontaneous esophageal rupture (SER/Boehhaave's syndrome).Patients undergoing VATS debridement/drainage were divided into:1. Lavage-Drainage Group (n = 11): Gastroscopically guided placement of a nasogastric tube through the esophageal fistula for continuous irrigation (iodinated saline) + standard thoracic/mediastinal drainage.2. Drainage Group (n = 13): Standard VATS debridement/drainage alone.No Difference: Operative time, ICU/hospital stay, mechanical ventilation...2025-07-0602 minSurgical Pioneering Podcast"Standardizing the Definition of Each Colon Cancer Segment: Delphi Consensus"Reviewed by Reza Lankarani M.D------------------------------------------------------------Diseases of the Colon & RectumDOI: 10.1097/DCR.0000000000003739Published online:June 2025------------------------------------------------------------This international Delphi consensus study addresses a critical gap in colorectal oncology: the lack of standardized anatomical definitions for colon cancer segments. Its primary strength lies in its rigorous methodology and global representation. The three-round Delphi process engaged 295 colorectal surgery experts from 28 countries across four continents, ensuring diverse perspectives and high retention rates (91% completed round 2; 89% all three rounds). The structured approach—using a 9-point Likert scale, predefined consensus thresholds (≥70% for strong agreement), iterative refinement, and a final consensus conference—enhances the validity and reliability of the findin...2025-07-0502 min
Surgical Pioneering Podcast"Standardizing the Definition of Each Colon Cancer Segment: Delphi Consensus"Reviewed by Reza Lankarani M.D------------------------------------------------------------Diseases of the Colon & RectumDOI: 10.1097/DCR.0000000000003739Published online:June 2025------------------------------------------------------------This international Delphi consensus study addresses a critical gap in colorectal oncology: the lack of standardized anatomical definitions for colon cancer segments. Its primary strength lies in its rigorous methodology and global representation. The three-round Delphi process engaged 295 colorectal surgery experts from 28 countries across four continents, ensuring diverse perspectives and high retention rates (91% completed round 2; 89% all three rounds). The structured approach—using a 9-point Likert scale, predefined consensus thresholds (≥70% for...2025-07-0502 minSurgical Pioneering Podcast"Homocysteine a novel biomarker for predicting irreversible transmural intestinal necrosis in patients with adhesive small bowel obstructionReviewed by Reza Lankarani M.D ------------------------------------------------------------Published: 24 June 2025https://doi.org/10.1186/s13017-025-00632-4World Journal of Emergency Surgery------------------------------------------------------------This prospective observational study by Zhu et al. (2025) investigates serum homocysteine (HCY) as a predictor of irreversible transmural intestinal necrosis (ITIN) in patients with adhesive small bowel obstruction (ASBO). The study demonstrates that elevated HCY levels are strongly associated with ITIN, outperforming established biomarkers and radiological signs in diagnostic accuracy. -----------------Below is a critical assessment of its key strengths: 1. Methodologically Sound & Clinically Focused: The study excels in addressing the critical need for timely bowel necrosis detection in ASBO. Its prospective design...2025-07-0302 min
Surgical Pioneering Podcast"Homocysteine a novel biomarker for predicting irreversible transmural intestinal necrosis in patients with adhesive small bowel obstruction"Reviewed by Reza Lankarani M.D ------------------------------------------------------------Published: 24 June 2025https://doi.org/10.1186/s13017-025-00632-4World Journal of Emergency Surgery------------------------------------------------------------This prospective observational study by Zhu et al. (2025) investigates serum homocysteine (HCY) as a predictor of irreversible transmural intestinal necrosis (ITIN) in patients with adhesive small bowel obstruction (ASBO). The study demonstrates that elevated HCY levels are strongly associated with ITIN, outperforming established biomarkers and radiological signs in diagnostic accuracy. -----------------Below is a critical assessment of its key strengths:2025-07-0302 minSurgical Pioneering Podcast“Prospective Sensory Outcomes for Targeted Nipple-areolaComplex Reinnervation in Gender-affirming Double IncisionMastectomy With Free NippleReviewed by Reza Lankarani M.DVolume 282, Number 1, July 2025DOI: 10.1097/SLA.0000000000006192Annals of SurgerySummary:This prospective cohort study by Remy et al. (2025) presents a significant contribution to gender-affirming surgery by rigorously evaluating the novel technique of Targeted Nipple-Areola Complex Reinnervation (TNR) during double-incision mastectomy with free nipple grafting (FNG). The primary strength lies in its comprehensive, prospective design, meticulously tracking sensory outcomes (quantitative monofilament testing and patient-reported questionnaires) in 25 patients (50 mastectomies) at multiple time points up to 12 months postoperatively. This longitudinal approach robustly demonstrates that TNR facilitates restoration of NAC and chest sensation to baseline within 3 months, with significant *improvement* over...2025-06-2902 min
Surgical Pioneering Podcast“Prospective Sensory Outcomes for Targeted Nipple-areolaComplex Reinnervation in Gender-affirming Double IncisionMastectomy With Free Nipple Grafting’Reviewed by Reza Lankarani M.DVolume 282, Number 1, July 2025DOI: 10.1097/SLA.0000000000006192Annals of SurgerySummary:This prospective cohort study by Remy et al. (2025) presents a significant contribution to gender-affirming surgery by rigorously evaluating the novel technique of Targeted Nipple-Areola Complex Reinnervation (TNR) during double-incision mastectomy with free nipple grafting (FNG). The primary strength lies in its comprehensive, prospective design, meticulously tracking sensory outcomes (quantitative monofilament testing and patient-reported questionnaires) in 25 patients (50 mastectomies) at multiple time points up...2025-06-2902 min
Surgical Pioneering Podcast"Surgical Risk Calculator: POTTER - A Paradigm Shift in Emergency General Surgery Risk Assessment"By Dr. Reza Lankarani----------------------------The POTTER (Predictive Optimal Trees in Emergency Surgery Risk) calculator represents a groundbreaking advancement in AI-driven surgical risk prediction, specifically designed for emergency general surgery (EGS) and laparotomy patients. Developed through collaboration between Massachusetts General Hospital (MGH) and Interpretable AI, POTTER leverages machine learning to provide transparent, accurate, and actionable risk assessments. This article synthesizes findings from multiple validation studies, including a pivotal 2024 prospective bi-institutional trial, to outline its clinical utility and transformative potential . The Journal of the American College of Surgeons (JACS) podcast episode and associated studies...2025-06-1701 minSurgical Pioneering Podcast"Surgical Risk Calculator: POTTER - A Paradigm Shift in Emergency General Surgery Risk Assessment"By Dr. Reza Lankarani----------------------------The POTTER (Predictive Optimal Trees in Emergency Surgery Risk) calculator represents a groundbreaking advancement in AI-driven surgical risk prediction, specifically designed for emergency general surgery (EGS) and laparotomy patients. Developed through collaboration between Massachusetts General Hospital (MGH) and Interpretable AI, POTTER leverages machine learning to provide transparent, accurate, and actionable risk assessments. This article synthesizes findings from multiple validation studies, including a pivotal 2024 prospective bi-institutional trial, to outline its clinical utility and transformative potential . The Journal of the American College of Surgeons (JACS) podcast episode and associated studies evaluate the POTTER (Predictive Optimal Trees in Emergency Surgery...2025-06-1701 minSurgical Pioneering Podcast"Echoes in the Rubble (Requiem for Tehran & Tel Aviv)"By Reza Lankarani MD (Verse 1 - Whispered, over detuned guitar)Stealth wings carve the moon tonight,F-35s bleed electric light—While Tehran sleeps in trembling rooms,A Shahed's cheap hum... the coming doom.(Chorus - Voice cracks, piano stains the silence)Oh, Iron Dome rains electric grace,On children's faces in this burning place—Seventy souls... three hundred more,SPICE-2000 wrote it on the floor...In Ramat Gan's dust... a red balloon,Hypersonic fire... came too soon.(Verse 2 - Military snare creeps in)Deep underground, the centrifuges sighed,LORA's vengeance tore inside—"Bavar-373"... a shattered shield,While Unit 8200 hacked the fi...2025-06-1503 min
Surgical Pioneering Podcast"Echoes in the Rubble (Requiem for Tehran & Tel Aviv)"By Reza Lankarani MD (Verse 1 - Whispered, over detuned guitar)Stealth wings carve the moon tonight,F-35s bleed electric light—While Tehran sleeps in trembling rooms,A Shahed's cheap hum... the coming doom.(Chorus - Voice cracks, piano stains the silence)Oh, Iron Dome rains electric grace,On children's faces in this burning place—Seventy souls... three hundred more,SPICE-2000 wrote it on the floor...In Ramat Gan's dust... a red balloon,Hype...2025-06-1503 minSurgical Pioneering PodcastEffects of the Lavage Through Fistula in Treatment of Spontaneous Esophageal Rupture by Combined Thoracoscop and Gastroscop"Effects of the Lavage Through Fistula in Treatment of Spontaneous Esophageal Rupture by Combined Thoracoscop and Gastroscop"Reviewed by Reza Lankarani --------------------------------World Journal of Emergency Surgeryhttps://doi.org/10.1186/s13017-025-00630-6Published: 07 June 2025--------------------------------This retrospective study (2014-2024, n = 24) evaluates a novel lavage-drainage technique for spontaneous esophageal rupture (SER/Boehhaave's syndrome). Patients undergoing VATS debridement/drainage were divided into:1. Lavage-Drainage Group (n = 11): Gastroscopically guided placement of a nasogastric tube through the esophageal fistula for continuous irrigation (iodinated saline) + standard thoracic/mediastinal drainage.2. Drainage Group (n = 13): Standard VATS debridement/drainage alone.Key Findings: ↓ 30-day Mortality: 0% vs. 15.38% (p = 0.029). ↓ Major Complications (Clavien-Dindo II-IV): 45.45% vs...2025-06-1502 min
Surgical Pioneering PodcastEffects of the Lavage Through Fistula in Treatment of Spontaneous Esophageal Rupture by Combined Thoracoscop and Gastroscop"Effects of the Lavage Through Fistula in Treatment of Spontaneous Esophageal Rupture by Combined Thoracoscop and Gastroscop"Reviewed by Reza Lankarani --------------------------------World Journal of Emergency Surgeryhttps://doi.org/10.1186/s13017-025-00630-6Published: 07 June 2025--------------------------------This retrospective study (2014-2024, n = 24) evaluates a novel lavage-drainage technique for spontaneous esophageal rupture (SER/Boehhaave's syndrome). Patients undergoing VATS debridement/drainage were divided into:1. Lavage-Drainage Group (n = 11): Gastroscopically guided placement of a nasogastric tube through the esophageal fistula for continuous irrigation (iodinated saline) +...2025-06-1502 min
Surgical Pioneering PodcastSymmetrization in Therapeutic Mammoplasty for Breast CancerReviewed by Reza Lankarani This editorial addresses the critical debate surrounding the timing of contralateral symmetrization following therapeutic mammoplasty—a procedure combining oncologic resection with breast reshaping. The authors juxtapose immediate symmetrization (performed concurrently with cancer surgery) against delayed approaches (secondary procedures post-recovery). Traditional rationale for delaying symmetrization emphasizes allowing radiation-induced breast contraction to stabilize, thereby optimizing symmetry outcomes. However, the authors highlight significant drawbacks of delayed strategies: psychological distress (e.g., embarrassment, social withdrawal), increased costs (additional surgeries, prolonged care), and systemic inefficiencies (post-COVID-19 resource constraints).Evidence from 1,130 patients across mu...2025-06-1301 minSurgical Pioneering PodcastSymmetrization in Therapeutic Mammoplasty for Breast CancerReviewed by Reza Lankarani This editorial addresses the critical debate surrounding the timing of contralateral symmetrization following therapeutic mammoplasty—a procedure combining oncologic resection with breast reshaping. The authors juxtapose immediate symmetrization (performed concurrently with cancer surgery) against delayed approaches (secondary procedures post-recovery). Traditional rationale for delaying symmetrization emphasizes allowing radiation-induced breast contraction to stabilize, thereby optimizing symmetry outcomes. However, the authors highlight significant drawbacks of delayed strategies: psychological distress (e.g., embarrassment, social withdrawal), increased costs (additional surgeries, prolonged care), and systemic inefficiencies (post-COVID-19 resource constraints).Evidence from 1,130 patients across multiple studies supports the safety and efficacy of immediate sy...2025-06-1301 min
Surgical Pioneering Podcast"Reza Lankarani - Carved in Bone"@LankaraniMD #carvedinbone , #lankaranimd , #rezalankarani , #rock , #psychedelicrock , #officialmusicvideo , #lyricvideo , #lyrics , #highenergytracks , #NewMusicRelease2025 , #newsong , @UnsignedArtists , @IndependentArtistsOriginal , @bestmusicvideo6266 , #MusicVideo , #NewRelease , #newmusic , #Identity , #Conformity , #Rebellion , #Sculpting , #Transformation , #Emotionhttps://music.youtube.com/@DrLankarani"Reza Lankarani - Carved in Bone"Why Reza Lankarani's Music is a Big Deal? The provided text poses a powerful exploration of identity, self-expressions, and the struggle against societal expectations. The speaker reflects on their experience of external influences-symbolized by chisels etching visions into their skin-trying to mold them into a prescribed identity. The repeated imagery of masks, shadows, and fractures signifies...2025-06-1200 min
Surgical Pioneering Podcast"Reza Lankarani - Carved in Bone"@LankaraniMD #carvedinbone , #lankaranimd , #rezalankarani , #rock , #psychedelicrock , #officialmusicvideo , #lyricvideo , #lyrics , #highenergytracks , #NewMusicRelease2025 , #newsong , @UnsignedArtists , @IndependentArtistsOriginal , @bestmusicvideo6266 , #MusicVideo , #NewRelease , #newmusic , #Identity , #Conformity , #Rebellion , #Sculpting , #Transformation , #Emotionhttps://music.youtube.com/@DrLankarani"Reza Lankarani - Carved in Bone"Why Reza Lankarani's Music is a Big Deal? The provided text poses a powerful exploration of identity, self-expressions, and the struggle against societal expectations. The speaker reflects on their experience of external influences-symbolized by chisels etching visions into their skin-trying to mold them into a prescribed identity. The repeated imagery of masks, shadows, and fractures signifies the pressure to conform to another's vision and the pain...2025-06-1200 minSurgical Pioneering PodcastRed Wine Versus White Wine Which Poses a Greater Cancer RiskRed Wine Versus White Wine Which Poses a Greater Cancer RiskThe Medical News Today article examines whether red wine is a healthier choice than white wine, focusing on cancer risks. Epidemiologists highlight that all alcoholic beverages, including wine, are classified as Group 1 carcinogens by the International Agency for Research on Cancer (IARC), linked to cancers of the breast, liver, and esophagus. While red wine contains polyphenols like resveratrol, which have antioxidant properties, the ethanol content negates potential benefits by promoting carcinogenesis through acetaldehyde, oxidative stress, and hormonal disruption. The article cites studies suggesting no significant difference in cancer risk between...2025-06-1201 min
Surgical Pioneering PodcastRed Wine Versus White Wine Which Poses a Greater Cancer RiskRed Wine Versus White Wine Which Poses a Greater Cancer RiskThe Medical News Today article examines whether red wine is a healthier choice than white wine, focusing on cancer risks. Epidemiologists highlight that all alcoholic beverages, including wine, are classified as Group 1 carcinogens by the International Agency for Research on Cancer (IARC), linked to cancers of the breast, liver, and esophagus. While red wine contains polyphenols like resveratrol, which have antioxidant properties, the ethanol content negates potential benefits by promoting carcinogenesis through acetaldehyde, oxidative stress, and hormonal disruption. The article cites studies suggesting no...2025-06-1201 minSurgical Pioneering PodcastReza Lankarani - Music as Medicine Journey Through the SoulMusic as Medicine Journey Through the Soul a transformative journey through the soul, as they harness the therapeutic power of music to heal and uplift. This mesmerizing collaboration is a testament to the boundless potential of music as medicine.https://open.spotify.com/track/7wur8pMOBOjuYHQprI4jOO?si=706e13e0f4564a15Reza Lankarani Get full access to Reza Lankarani at lankarani.substack.com/subscribe2025-05-0506 min
Surgical Pioneering PodcastReza Lankarani - Music as Medicine Journey Through the SoulMusic as Medicine Journey Through the Soul a transformative journey through the soul, as they harness the therapeutic power of music to heal and uplift. This mesmerizing collaboration is a testament to the boundless potential of music as medicine.https://open.spotify.com/track/7wur8pMOBOjuYHQprI4jOO?si=706e13e0f4564a15Reza Lankarani Get full access to Reza Lankarani at lankarani.substack.com/subscribe2025-05-0506 minSurgical Pioneering Podcast"Vagilangelo Procedure: A Scientific Validation Critique"This source, presented as a peer-reviewed scientific validation, examines the Vagilangelo® procedure, a minimally invasive vaginal rejuvenation technique using sutures and PRP injections. While acknowledging the procedure's potential as an alternative to traditional methods, the text highlights significant weaknesses, including a lack of peer-reviewed clinical trials and long-term follow-up data. It also points out the uncertainty of PRP's benefits in this application and the risk of overstating outcomes based on anecdotal evidence. The author concludes by recommending caution due to the limited scientific backing and calling for rigorous research to validate the procedure's efficacy and safety compared to established techniques.T...2025-04-2810 min
Surgical Pioneering Podcast"Vagilangelo Procedure: A Scientific Validation Critique"This source, presented as a peer-reviewed scientific validation, examines the Vagilangelo® procedure, a minimally invasive vaginal rejuvenation technique using sutures and PRP injections. While acknowledging the procedure's potential as an alternative to traditional methods, the text highlights significant weaknesses, including a lack of peer-reviewed clinical trials and long-term follow-up data. It also points out the uncertainty of PRP's benefits in this application and the risk of overstating outcomes based on anecdotal evidence. The author concludes by recommending caution due to the limited scientific backing and calling for rigorous research to validate the procedure's efficacy and safety compared to established t...2025-04-2810 minSurgical Pioneering Podcast"Blood on their hands while sipping champaign"Get ready for "Blood on their Hands while Sipping Champagne"! @LankaraniMD unleashes a fierce anti-war anthem, boldly exposing those behind the chaos and devastation. This eye-opening music video is an absolute must-see for fans of alternative rock and world music. With gritty garage rock vibes and infectious hooks, it echoes the best hits from Monstercat and Ultra Music. The captivating piano melody, reminiscent of The Piano Guys and Jon Schmidt, beautifully complements the hard-hitting rap verses. If you love the vibes of Pentatonix, Boyce Avenue, and Adam Neely, this genre-defying track is for you! Spanning platforms from Vevo to YouTube Music...2025-04-2602 min
Surgical Pioneering Podcast"Blood on their hands while sipping champaign"Get ready for "Blood on their Hands while Sipping Champagne"! @LankaraniMD unleashes a fierce anti-war anthem, boldly exposing those behind the chaos and devastation. This eye-opening music video is an absolute must-see for fans of alternative rock and world music. With gritty garage rock vibes and infectious hooks, it echoes the best hits from Monstercat and Ultra Music. The captivating piano melody, reminiscent of The Piano Guys and Jon Schmidt, beautifully complements the hard-hitting rap verses. If you love the vibes of Pentatonix, Boyce Avenue, and Adam Neely, this genre-defying track is for you! Spanning platforms from Vevo to YouTub...2025-04-2602 min
Surgical Pioneering Podcast"The Vagilangelo® Procedure Scientific Validation""Interview is with Dr. Reza Lankarani, General Surgeon and Surgical Innovation Lead/Researcher and the administrator of Surgical Pioneering newsletter. "The Vagilangelo® procedure, detailed on https://www.vagilangelo.com, is a minimally invasive vaginal rejuvenation technique.However, the absence of functional data or longitudinal follow-up limits its immediate clinical applicability. Future work should integrate this anatomical data with patient-reported outcomes, as emphasized in for aesthetic surgery research. The article also underscores the need for sustained funding in basic surgical science, as neuroanatomical studies require resource-intensive methodologies. While the research advances theoretical knowledge, its impact on surgical training and global health d...2025-04-2505 min
Surgical Pioneering Podcast"The Vagilangelo® Procedure Scientific Validation""Interview is with Dr. Reza Lankarani, General Surgeon and Surgical Innovation Lead/Researcher and the administrator of Surgical Pioneering newsletter. "The Vagilangelo® procedure, detailed on https://www.vagilangelo.com, is a minimally invasive vaginal rejuvenation technique.However, the absence of functional data or longitudinal follow-up limits its immediate clinical applicability. Future work should integrate this anatomical data with patient-reported outcomes, as emphasized in for aesthetic surgery research. The article also underscores the need for sustained funding in basic surgical science, as neuroanatomical studies require resource-intensive methodologies. While the research advances theoretical knowledge, its i...2025-04-2505 min
Surgical Pioneering Podcast"The Vagilangelo® Procedure: A minimally invasive vaginal rejuvenation technique"April 24, 2025Peer-reviewed by Reza Lankarani M.DSummary:The Vagilangelo® procedure, detailed on https://www.vagilangelo.com, is a minimally invasive vaginal rejuvenation technique developed by Dr. Amir Marashi. It aims to enhance sexual satisfaction by restoring the vagina’s natural angle using internal sutures and PRP injections to stimulate tissue regeneration. Performed under local anesthesia in 30 minutes, it offers a quick recovery (2-3 weeks) and is positioned as an alternative to traditional vaginoplasty.The main reference mentioned for the procedure is the study contributes to the growing body of meta-research in surgery by addressing a historically understudied anatomical structure. Its find...2025-04-2405 min
Surgical Pioneering Podcast"The Vagilangelo® Procedure: A minimally invasive vaginal rejuvenation technique"April 24, 2025Peer-reviewed by Reza Lankarani M.DSummary:The Vagilangelo® procedure, detailed on https://www.vagilangelo.com, is a minimally invasive vaginal rejuvenation technique developed by Dr. Amir Marashi. It aims to enhance sexual satisfaction by restoring the vagina’s natural angle using internal sutures and PRP injections to stimulate tissue regeneration. Performed under local anesthesia in 30 minutes, it offers a quick recovery (2-3 weeks) and is positioned as an alternative to traditional vaginoplasty.The main reference mentioned for the procedure is the study contributes to the growing body of meta-research in surgery by a...2025-04-2405 min
Surgical Pioneering PodcastReza Lankarani - "Celestial Interrogation"Dive headfirst into the electrifying sonic realm of "Celestial Interrogation" by Reza Lankarani M.D, an exhilarating blend of alternative rock and jazz fusion! This enchanting track echoes the vibrant styles of Pentatonix and Boyce Avenue, featuring rich instrumentation and laid-back beats that will captivate any music lover. Experience the intricate rhythms inspired by jazz and the reflective vibes of must-have indie tracks. If you relish Rick Beato's insightful music breakdowns, you'll be thrilled to explore the depths of this composition. With its calming essence, "Celestial Interrogation" is a gem for fans of meditativemind and those who...2025-04-2203 minSurgical Pioneering PodcastReza Lankarani - "Celestial Interrogation"Dive headfirst into the electrifying sonic realm of "Celestial Interrogation" by Reza Lankarani M.D, an exhilarating blend of alternative rock and jazz fusion! This enchanting track echoes the vibrant styles of Pentatonix and Boyce Avenue, featuring rich instrumentation and laid-back beats that will captivate any music lover. Experience the intricate rhythms inspired by jazz and the reflective vibes of must-have indie tracks. If you relish Rick Beato's insightful music breakdowns, you'll be thrilled to explore the depths of this composition. With its calming essence, "Celestial Interrogation" is a gem for fans of meditativemind and those who crave unsigned artists...2025-04-2203 minSurgical Pioneering Podcast"Sigmoid Resection vs Conservative Treatment After DiverticulitisPrespecified 4-Year Analysis of the LASER Randomized Clinical analysis"In summary, the LASER trial’s 4-year analysis indicates that while elective sigmoid resection is highly effective in preventing diverticulitis recurrence, it does not offer a sustained QOL advantage over conservative treatment in the long term. The study’s strengths include rigorous randomization, high follow-up adherence (92%), and intention-to-treat/per-protocol analyses.However, limitations such as premature termination, small sample size (n = 90), lack of blinding, and heterogeneity in inclusion criteria (recurrent vs. persistent pain) temper generalizability. Comparisons with the DIRECT trial reveal discrepancies in outcomes, likely due to differing baseline patient profiles (e.g., higher recurrent diverticulitis prevalence in LASER). These findings unde...2025-04-2200 min
Surgical Pioneering Podcast"Sigmoid Resection vs Conservative Treatment After DiverticulitisPrespecified 4-Year Analysis of the LASER Randomized Clinical analysis"In summary, the LASER trial’s 4-year analysis indicates that while elective sigmoid resection is highly effective in preventing diverticulitis recurrence, it does not offer a sustained QOL advantage over conservative treatment in the long term. The study’s strengths include rigorous randomization, high follow-up adherence (92%), and intention-to-treat/per-protocol analyses.However, limitations such as premature termination, small sample size (n = 90), lack of blinding, and heterogeneity in inclusion criteria (recurrent vs. persistent pain) temper generalizability. Comparisons with the DIRECT trial reveal discrepancies in outcomes, likely due to differing baseline patient profiles (e.g., higher recurrent diverticulitis prev...2025-04-2200 min
Surgical Pioneering Podcast"Reza Lankarani - Carved in Bone""Reza Lankarani - Carved in Bone"The provided text poses a powerful exploration of identity, self-expressions, and the struggle against societal expectations. The speaker reflects on their experience of external influences-symbolized by chisels etching visions into their skin-trying to mold them into a prescribed identity. The repeated imagery of masks, shadows, and fractures signifies the pressure to conform to another's vision and the pain of internal conflict as they grapple with their reality. There's a yearning for authenticity amidst an environment that seeks to manipulate the individual, transforming them into a "clockwork soul." The poem emphasizes resilience...2025-04-1903 min
Surgical Pioneering PodcastReza Lankarani-Fallen Angel"Reza Lankarani - Fallen Angel"(Verse 1) I was the healer, the light in their eyes, A young bright doctor, loved by the skies. But love called me, begged me to leap, I fell from the height, my promises to keep. Her constant posts, a thorn in my side, Her laughter turned cruel, no place to hide. I was racked with pain after falling down, A hero for her, now lost in the crowd. ...2025-04-1003 min