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Roberta Foresti

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about enzymes & moleculesabout enzymes & molecules#7 - PARCC - Dr. Alain TedguiIn the second episode of our Special Interviews Series with Institute Directors we invited Dr Alain Tedgui, former Director of the Paris-Centre de Recherche Cardiovasculaire (PARCC, 2009-2018). Dr Tedgui gave us a wonderful overview of the strategies behind the founding of PARRC as a major French scientific institute dedicated to study cardiovascular disease as well as the original plans that were initiated in the 70s for the realization of this novel Institution. Dr Tedgui also explained to us his life and professional journey, coming to France from Algeria as a young boy and progressing to become a highly recognized...2025-02-131h 03L-Aħbarijiet fil-QosorL-Aħbarijiet fil-QosorL-Aħbarijiet fil-Qosor – 14/01/2025 – MaltiIl-punti ewlenin: is-Segretarju Ġenerali tan-NATO Mark Rutte u l-mexxejja tal-UE jingħaqdu biex jindirizzaw l-isfidi għas-sigurtà; il-President tal-Parlament Ewropew Roberta Metsola ltaqgħet mal-Kanċillier Awstrijak u mas-Segretarju Ġenerali tan-NATO; il-Kumitat għall-Agrikoltura u l-Iżvilupp Rurali ddiskuta l-baġit għall-2026, il-politika dwar l-inbid, u l-monitoraġġ tal-foresti.2025-01-1401 minabout enzymes & moleculesabout enzymes & molecules#6 - How Noise Affects Your Health - Dr. Andreas Daiber The topic of our discussion today is environmental stress and how it affects our susceptibility to develop diseases. We are familiar with the danger of air pollution, which increases lung disease and is being implicated in neurodegeneration or cardiovascular disorders, but we often do not consider noise, which is a very important external stressor. We are surrounded by noise, especially in the urban space: cars, public transport, construction works etc. are all a continuous source of noise. How does noise impact our health? Today's host Dr Andreas Daiber, full Professor in Molecular Cardiology at the University Medical Center Mainz...2024-10-2557 minI Notturni di Ameria Radio - The Ameria Radio NocturnesI Notturni di Ameria Radio - The Ameria Radio NocturnesI Notturni di Ameria Radio del 11 ottobre 2024 - L'opera barocca / A. Vivladi, L'Olimpiade / Rinaldo AlessandriniL’opera baroccaAntonio Vivaldi (1678-1741) - L’Olimpiade RV 725Opera in tre atti Sara Mingardo (contralto), LicidaRoberta Invernizzi (soprano), MegacleSonia Prina (contralto), AristeaMarianna Kulikova (mezzo-soprano), ArgeneLaura Giordano (soprano), AmintaRiccardo Novaro (baritono), ClisteneSergio Foresti (basso), Alcandro Concerto ItalianoRinaldo Alessandrini Libretto2024-10-112h 56about enzymes & moleculesabout enzymes & molecules#5 - Institut Cochin - Dr Florence Niedergang This is the first episode of our Special Interviews Series with Institute Directors, where we discuss the opportunities and challenges that come with being in charge of a research institute. The expertise required for this job is multi-varied: the director needs to develop ambitious research goals by relying on their teams' skills and scientific interests, leveraging the input of technical platforms at the service of science, coordinate the administrative support and constructively work with supervising bodies. This is no easy task: directors often have to learn on the job, as in their "former" life they were originally "only" scientists! ...2024-09-0226 minabout enzymes & moleculesabout enzymes & molecules#4 - NRF2 - Dr. Albena Dinkova-Kostova For our fourth episode we will talk about a special system that is very important for protecting the organism against stress: the NRF2 transcription factor. It is the master regulator of the stress response, which is responsible for increasing the expression of a long list of genes that help to combat stress and restore cellular homeostasis. Interestingly, NRF2 is activated by stressful stimuli but also by plant-derived natural compounds, showing how nature has evolved to harness the power of plants to provide benefits for our body. In opposition to its fundamental role in protection, NRF2 also has a dark...2024-03-1445 minabout enzymes & moleculesabout enzymes & molecules#3 - The Heme Dichotomy - Dr. Francesca VinchiIn the 3rd episode of this series, Dr Vinchi and I will talk about different facets of heme biology, why heme is crucial in normal physiology and why it exerts a deleterious action when it is not tightly bound to a protein. We will further examine the modulatory role of heme in diseases characterized by excessive free heme in circulation and how endothelial cells in vessels and specific immune cells, called macrophages, adapt their function in response to heme. We hope you will enjoy our conversation with Dr Vinchi and learn more about the heme...2024-02-0456 minabout enzymes & moleculesabout enzymes & molecules#2 - Bilirubin - Dr. Roland StockerIn the second episode of our podcast 'about enzymes & molecules', we welcome Dr Roland Stocker to talk about bilirubin, the antioxidant molecule produced during heme breakdown by heme oxygenase. Dr Stocker will tell us about the inspiration that led to hypothesize that bilirubin possesses antioxidant properties, the thorough methodological approaches that were required to precisely demonstrate this effect, and how bilirubin can protect cellular membranes, albumin, lipoproteins and other cellular structures from the damage caused by free radicals. We will also discuss the epidemiological studies that support an important role for bilirubin in mitigating cardiovascular disease and diabetes complications...2023-11-191h 12about enzymes & moleculesabout enzymes & molecules#0 - Introduction to PodcastWelcome to the science podcast about enzymes & molecules, where we will discuss the fascinating world of enzymes & molecules and their role in nature and human biology. I am Dr. Roberta Foresti, professor of Biochemistry at the University of Paris Est Créteil and working as a scientist at the Mondor Institute of Biomedical Research in France. During the podcast we will be exploring several scientific topics highlighting how enzymes and the molecules they transform contribute to life processes, how they can malfunction during disease, and how some of the discoveries of enzymatic processes can lead to the development of d...2023-09-1203 minabout enzymes & moleculesabout enzymes & molecules#1 - Heme Oxygenase & Carbon Monoxide - Dr. Leo Otterbein Welcome to the first episode of the science podcast about enzymes & molecules. Today we welcome our first guest, Leo Otterbein, PhD, Professor of Surgery and principal investigator of the Otterbein Lab at Harvard Medical School in Boston, USA. Dr. Otterbein has published fundamental findings on heme oxygenase and its product, carbon monoxide, establishing the crucial role of this system in inflammation. One of the primary goals of the Otterbein Lab is to study the benefit of carbon monoxide in low doses to help against organ injury, for example in the heart, kidney or lungs, trying to understand the mechanisms...2023-09-1239 min