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The Joe Cohen Show
The Joe Cohen ShowBiohacking Menopause and Women's Health with Zora BenhamouJoin Joe Cohen and gerontologist Zora Benhamou, host of the Hack My Age podcast, as they discuss biohacking for women's health, anti-aging, and menopause. Zora shares her personal experiences and professional insights on topics like the importance of tracking hormones, testing for optimal health, the impact of lifestyle choices, and the use of supplements and alternative therapies. They also discuss the effects of thyroid hormones and the controversial yet effective use of Botox. Learn actionable tips to optimize your body and mind at any age.- Check out SelfDecode: https://selfdecode.com/...
2025-06-131h 01The Joe Cohen Show
The Joe Cohen ShowDetoxification, Biohacking & Liposomal Supplements Explained with Dr. Chris ShadeJoin Joe Cohen on The Joe Cohen Show as he speaks with Dr. Chris Shade, founder and CEO of Quicksilver Scientific. In this insightful episode, they dive deep into the world of biohacking, detoxification, and the science behind liposomal supplements. Dr. Shade explains the intricacies of mercury detox, the role of glutathione, the benefits of liposomal delivery systems, and how certain supplements can optimize health. They also discuss the challenges of current detoxification methods and the incredible advancements in the field, including liposomal technology for enhanced absorption and effectiveness. This episode is a mus...
2025-05-301h 11The Joe Cohen Show
The Joe Cohen ShowUnderstanding Functional Medicine with Dr. Ben WeitzJoe Cohen talks with Dr. Ben Weitz, a functional medicine practitioner with over 35 years of experience, about his approach to addressing gut health and autoimmune conditions.Ben explains how functional medicine focuses on finding and treating root causes, such as diet, lifestyle, microbiome imbalances, and chronic infections, rather than just managing symptoms. They discuss how conditions like IBS and autoimmune diseases are connected to factors like food sensitivities, toxins, and gut health, and explore various testing methods and treatment strategies. Ben also shares practical insights from his clinical practice and ongoing work in th...
2025-05-2336 minThe Joe Cohen Show
The Joe Cohen ShowHow to Boost Stem Cells Naturally for Better Healing and Aging with Christian DrapeauJoe sits down with Christian Drapeau, a stem cell expert with over 20 years of research under his belt, to talk about how the body repairs itself, and how we can help it do a better job. They get into what stem cells actually do, why we lose them as we age, and how that affects recovery, energy, and long-term health. Christian shares simple, natural ways to support stem cell activity, like fasting, exercise, and plant-based supplements. They also talk about stem cell therapies and how they compare to everyday strategies you can use to support yo...
2025-05-1646 minThe Joe Cohen Show
The Joe Cohen ShowCan Supplements Make You More Monogamous?In this episode of The Joe Cohen Show, Joe takes a personal and scientific look at monogamy, exploring why some people feel more content in exclusive relationships than others. He breaks down what research says about the hormone vasopressin and its role in bonding, loyalty, and long-term attachment, drawing from both animal studies and genetic findings. Joe also shares a surprising result from his own supplement routine, where taking L-arginine and glycine seemed to shift his natural tendencies toward greater monogamy. It's a unique mix of biohacking, hormones, and human behavior you won’t wan...
2025-05-0923 minThe Joe Cohen Show
The Joe Cohen ShowA Practitioner’s Guide to Personalized HealthIn this special episode, Joe sits down with health coach and SelfDecode Pro user Joline Schaaphok to walk through her personalized health insights using genetic data. They explore everything from supplement recommendations and food sensitivities to overlooked risk factors like anemia and cardiovascular health. It’s a real-time example of how genetic reports, labs, and lifestyle data can work together to uncover actionable insights. Whether you're a practitioner, a biohacker, or just curious about precision health, this live analysis offers a behind-the-scenes look at how to turn data into meaningful change.- Check out...
2025-05-0247 minThe Joe Cohen Show
The Joe Cohen ShowHow DNA Data is Revolutionizing Personalized Medicine with Sasha PowellIn this episode of the Joe Cohen Show, host Joe Cohen discusses the power of biohacking and precision health with Sasha Powell, a nurse practitioner and integrative healthcare provider. Sasha shares her experience using DNA data to optimize her patients' health outcomes, focusing on areas like hormone and weight management, mental health, and overall well-being. They dive into the specifics of how genetic insights can personalize treatment plans, leading to better, faster results. Whether it's diagnosing mental health issues more accurately or managing physical health conditions like diabetes and inflammation, Sasha highlights the transformative impact of...
2025-04-251h 08The Joe Cohen Show
The Joe Cohen ShowUnderstanding Glutamate: Anxiety, OCD, and Brain HealthIn this solo episode, Joe Cohen explores the powerful effects of glutamate on the brain and how elevated levels can drive anxiety, obsessive thoughts, and overstimulation. He shares insights from personal experiments with supplements like AKG, proline, and arginine and explains how they impacted his mental state, motivation, and focus.Joe also breaks down the symptoms tied to excess glutamate, from headaches and insomnia to mood swings and neurological issues. He discusses why certain people are more sensitive to glutamate due to genetic differences, and outlines what’s helped him manage it, including specific doses of...
2025-04-2222 minThe Joe Cohen Show
The Joe Cohen ShowThe Truth About Microbiome Testing with Kiran KrishnanIn this eye-opening episode of The Joe Cohen Show, Joe sits down with microbiologist and biotech entrepreneur Kiran Krishnan to dismantle the myths and marketing hype surrounding microbiome testing. Drawing parallels between the DNA and microbiome industries, they expose the scientific shortcuts, technological flaws, and misleading health claims being sold to consumers.Krishnan, the mind behind one of the few microbiome platforms used in published research, breaks down what a legitimate test looks like and why most tests on the market fall short, sometimes by as much as 70% in accuracy. The conversation also ex...
2025-04-1854 minThe Joe Cohen Show
The Joe Cohen ShowThe DNA Testing Industry Is Broken. Here's What We're Doing About ItMost genetic testing companies promise personalized health insights, but their reports barely scratch the surface, often analyzing just a handful of genetic variants. In this episode, Joe Cohen shares what happened when the SelfDecode team took a close look at dozens of these reports to understand how and why they fall short and what it actually takes to do it right.He shares how SelfDecode analyzes hundreds of thousands (sometimes millions) of variants per report, uses advanced technology to generate more accurate results, and integrates labs and lifestyle data to deliver truly actionable recommendations. ...
2025-04-1509 minThe Joe Cohen Show
The Joe Cohen ShowThe Future of Personalized Health and Nutrition with Mark NottonIn this episode, Joe Cohen talks with Mark Notton, founder of Revive DNA, about how your DNA can shape your sleep, energy, and long-term health.After helping his wife recover from a chronic autoimmune condition using a personalized nutrition approach, Mark left his executive career at Samsung to launch a health tech company.Now, Revive DNA is making science-backed, DNA-driven wellness accessible to more people with support from major institutions and powered by OmicsEdge technology.Tune in for a deep dive into the future of personalized health and what most programs are still...
2025-04-1133 minThe Joe Cohen Show
The Joe Cohen ShowShould You Take This? L. Plantarum for Bloating, Brain Fog & InflammationIn this episode, Joe discusses the benefits of the probiotic L. Plantarum, specifically the 299V strain. He talks about its effectiveness in reducing gas, improving mood, exercise recovery, and more. He shares how he personalizes his probiotic routine using SelfDecode, why the specific strain matters more than the brand, and how he takes higher doses to really feel a difference. If you're dealing with gut issues or just want to understand how probiotics can affect things like immunity, allergies, mood, or even homocysteine levels, there’s a lot in here you’ll find useful.Tune in to...
2025-04-0820 minThe Joe Cohen Show
The Joe Cohen ShowUnlocking Longevity: Biohacking, DNA Testing & Stress Management w/ Martin KremmerJoin Joe Cohen in this insightful episode as he interviews Martin Kremmer, CEO and co-founder of BioWatch and FreeAge. Martin, a pioneer in the Danish biohacking scene, shares his company's innovative approach to DNA and epigenetic testing to develop personalized longevity plans. They discuss the importance of combining different types of data, the future of functional health, and the role of stress management in achieving optimal health. Martin also introduces the Copenhagen Health Week and emphasizes the significance of simple lifestyle changes for long-term health. Don't miss this comprehensive talk on biohacking, health tech, and mu...
2025-04-0446 minThe Joe Cohen Show
The Joe Cohen ShowThe Truth About Bryan Johnson’s Blueprint: What Works & What Doesn’tIs Bryan Johnson’s anti-aging regimen the ultimate blueprint for health, or just another one-size-fits-all approach? In this episode, Joe Cohen breaks down Johnson’s protocol, highlighting what works, what doesn’t, and why personalization is key.Joe shares his own experiences and expert insights to help you optimize your health on your own terms.- Discover the pros and cons of Bryan Johnson’s approach- Why personalization matters more than a strict regimen- The best practices for sleep, nutrition, and longevityJoin us for a deep dive int...
2025-04-011h 05The Joe Cohen Show
The Joe Cohen ShowThe Future of Regenerative Medicine: Stem Cells, Exosomes & Anti-Aging Breakthroughs with Dr. Brigitte HanlyIn this episode, Joe Cohen sits down with Dr. Brigitte Hanly, CEO, Chief Scientist, and co-founder of Stemaid Institute, to explore the cutting-edge world of stem cell therapy. They discuss how pluripotent stem cells and exosomes can optimize health, repair injuries, and even slow aging. Joe shares his firsthand experience with the treatments, including their impact on immune function, brain health, and inflammation. Plus, they dive into the ethics of stem cell research and the future of regenerative medicine. If you’re curious about biohacking, longevity, and the science behind cellular rejuvenation, this is an epis...
2025-03-281h 02The Joe Cohen Show
The Joe Cohen ShowShould You Take This? The Surprising Benefits of L. Reuteri for Gut Health, Immunity & MoreCan a single probiotic strain transform your gut, lower cholesterol, and even help with food sensitivities?In this episode of The Joe Cohen Show, we dive into the fascinating research behind Lactobacillus reuteri. Joe shares his personal experiments and breaks down the science on how L. reuteri may support digestion, reduce inflammation, and even impact weight and skin health. Should you add this probiotic to your regimen? Tune in to find out!- Check out SelfDecode: https://selfdecode.com/- Join Joe’s online community: https://thejoecohenshow.com/ 
2025-03-2513 minThe Joe Cohen Show
The Joe Cohen ShowOvercoming Chronic Migraines and Fatigue with Dr. Elena GrossDr. Elena Gross joins Joe Cohen to share her journey from debilitating chronic migraines to becoming a neuroscience researcher and entrepreneur. They explore the role of mitochondrial dysfunction in migraines, how ketosis can optimize brain energy, and the importance of personalized health approaches. Joe and Elena break down the science behind oxidative stress, genetic risk factors, and key nutrients that support migraine management. Tune in for expert insights on biohacking migraines and optimizing your brain health!- Check out SelfDecode: https://selfdecode.com/- Join Joe’s online community: https://thejoecohenshow.com...
2025-03-211h 07The Joe Cohen Show
The Joe Cohen ShowWhy the Genova NutrEval Test Falls Short (Honest Review)In this episode of The Joe Cohen Show, Joe shares his honest review of the Genova NutrEval FMV amino acids test.He discusses the challenges of interpreting the results, the differences between urine and blood samples, and key insights related to antioxidant support, mitochondrial function, and nutrient needs.Considering the NutrEval test? This episode offers a detailed look at what to expect and important factors to consider.- Check out SelfDecode: https://selfdecode.com/- Join Joe’s online community: https://thejoecohenshow.com/ 
2025-03-1830 minThe Joe Cohen Show
The Joe Cohen ShowWhat is EFT? The Simple Technique That Can Transform Your Life with Brad YatesWhat if a simple technique could break down mental barriers, eliminate stress, and unlock peak performance? Meet Brad Yates, the legendary "EFT Wizard," whose tapping techniques have transformed millions of lives. In this episode, Joe sits down with Brad to reveal how Emotional Freedom Techniques (EFT) can help you clear emotional blocks, optimize your mindset, and take control of your well-being. Whether you're an entrepreneur, athlete, or just someone looking to elevate your life—this episode gives you an interesting and new approach to unshakable confidence, success, and inner peace.- Check...
2025-03-1458 minThe Joe Cohen Show
The Joe Cohen ShowThe Truth About GLP-1 & Ozempic: Natural Hacks for Weight Loss & Blood Sugar ControlAre you curious about the science behind GLP-1 agonists like Ozempic? Want to know how you can naturally support weight loss and blood sugar regulation without relying on medication?In this episode of The Joe Cohen Show, we dive deep into the world of GLP-1, exploring natural alternatives that can help suppress hunger, enhance metabolism, and optimize your health. From cutting-edge supplements to simple lifestyle tweaks, this episode is packed with actionable insights.Tune in now to discover:What GLP-1 agonists do and why they’re trendingThe truth about their ro...
2025-03-1122 minThe Joe Cohen Show
The Joe Cohen ShowWhole Genome Sequencing & The Future of Health with Dr. Puya YazdiIs the genetics industry full of BS? Joe Cohen sits down with Dr. Puya Yazdi, co-founder of SelfDecode, to expose the real science behind genetic testing, polygenic risk scores, and why most DNA reports are giving you half-truths (or worse—total garbage).If you care about your health, longevity, and actually understanding what your genes say about you, this episode is a must-listen. Buckle up—this one's a game-changer.- Check out SelfDecode: https://selfdecode.com/- Join Joe’s online community: https://thejoecohenshow.com/
2025-03-0744 minThe Joe Cohen Show
The Joe Cohen ShowShould You Take This? L. fermentum – Immunity, Glutathione and InflammationIn this episode of The Joe Cohen Show, Joe dives into the world of probiotics and biohacking with a deep dive into Lactobacillus fermentum. He shares his personal experience megadosing this unique probiotic, which has been linked to boosting glutathione levels—one of the body's most powerful antioxidants. Joe discusses the science behind L. fermentum, its potential benefits, and whether he's noticed any significant effects. Tune in to explore the latest in supplementation, self-experimentation, and cutting-edge health optimization!- Check out SelfDecode: https://selfdecode.com/- Join Joe’s online community: https://thejoecohenshow.com/
2025-03-0414 minThe Joe Cohen Show
The Joe Cohen ShowA Deep Dive into Wild Health & DNA AnalysisIn this episode of The Joe Cohen Show, we take a deep dive into genetic reports, specifically analyzing the Wild Health Report. Joe breaks down the strengths and weaknesses of these reports, highlighting the common pitfalls in genetic testing and how they often analyze only a limited set of variants. He also introduces a new and improved alternative: the 100X Wildly Healthy Functional DNA Report. Tune in to discover what makes a genetic report truly effective, how to interpret DNA-based diet and nutrition insights, and why a more comprehensive approach can revolutionize personalized health optimization. Don't miss this insightful...
2025-02-2819 minThe Joe Cohen Show
The Joe Cohen ShowChoosing the Best Air Purifier And Why It MattersIn this episode of The Joe Cohen Show, Joe explores the science of air purification and why investing in the right air purifiers and air filters is essential for optimizing health. He breaks down how poor indoor air quality—filled with mold spores, VOCs, and airborne pollutants—can impact energy levels, cognitive function, and inflammation. Joe shares his biohacking approach to selecting the most effective air filtration systems, including the latest technology for achieving cleaner air at home. If you're looking to upgrade your air quality, reduce toxins, and take control of your environ...
2025-02-2518 minThe Joe Cohen Show
The Joe Cohen ShowBiohacking for Women: Melanie Avalon on Optimizing Health & PerformanceJoin host Joe Cohen as he sits down with biohacker, actress, and health influencer Melanie Avalon for an insightful discussion on women and biohacking.Melanie shares her top biohacks, secrets to boosting performance, and even some surprising drinking biohacks. As the host of multiple health-focused podcasts, founder of AvalonX, and author of What, When, Wine, Melanie brings a wealth of knowledge on intermittent fasting, paleo-style nutrition, and longevity strategies. Get 10% OFF on https://avalonx.us/ by using coupon code ‘JOE’- Check out SelfDecode: https://selfdecode.com/- Join Joe’s...
2025-02-211h 25The Joe Cohen Show
The Joe Cohen ShowShould You Take This? L. Rhamnosus – GABA, Mood, and Heart HealthIn this episode of Should You Take This?, host Joe Cohen dives deep into Lactobacillus rhamnosus GG (L. Rhamnosus GG)—one of the most researched probiotic strains for gut health, brain function, and heart health.Joe shares his megadosing experiment, where he took 375 billion CFU of L. Rhamnosus in one day—25x the standard dose—to test its effects on mood, cognition, digestion, and cardiovascular health. He breaks down the scientific research behind Lactobacillus rhamnosus, explaining how it can:✔ Reduce excess glutamate and increase GABA, leading to improved mood and mental clarity✔ Lower TMAO levels...
2025-02-1823 minThe Joe Cohen Show
The Joe Cohen ShowShould You Take This?: B. Longum – The Probiotic for Gut & Brain HealthIn this episode of Should You Take This?, host Joe Cohen dives deep into one of his top three favorite probiotics—Bifidobacterium longum. If you've struggled with bloating, digestion issues, or simply want to optimize your gut health, this probiotic might be a game-changer.Joe shares his personal experience with B. longum, breaking down its effectiveness in reducing gas, improving digestion, and supporting overall health. He also explores the scientific research behind it, discussing its potential benefits for mood, immunity, and inflammation.Tune in to learn whether B. longum is the right probiotic fo...
2025-02-1412 minThe Joe Cohen Show
The Joe Cohen ShowBest of Season 7: Highlights & Health-Changing Moments from ExpertsIn this special "Best of Season 7" episode, we’re revisiting the most impactful, inspiring, and thought-provoking moments from our standout interviews this season. From groundbreaking health hacks and personal growth strategies to expert insights on optimizing your life, these are the clips that sparked the biggest conversations. Whether you're a long-time listener or new to the show, this episode is packed with must-hear wisdom from our incredible guests. Tune in for a quick recap of what made Season 7 unforgettable! - Check out SelfDecode: https://selfdecode.com/ - Join Joe’s online community: https://thejoecohenshow.com/
2024-09-2039 minThe Joe Cohen Show
The Joe Cohen ShowDigital Detox, Cutting-Edge Therapies, and Unique Biohacking Tricks with Jack SmithIn this episode Joe sits down with Jack Smith, known for his pioneering biohacking experiments. Jack shares his biohacking journey, highlighting unique health devices like the Pulse PEMF machine, EES cube, Altwork desk, and Oura Ring.  He also delves into therapies such as ketamine for mental wellness, GAINSWave, and resistant starch for gut health.  Through discussions on neurofeedback, silent retreats, and advanced wellness practices, Jack underscores his dedication to health optimization techniques and consistent lab testing. You can follow his ongoing experiments on X @_jacksmith Interested in joining the up...
2024-09-131h 26The Joe Cohen Show
The Joe Cohen ShowRevitalize Your Love Life: Mastering Intimacy with Dr. Saida Desilet And Aaron MichaelIn this episode, Aaron Michael and Dr. Saida Desilet discuss practical tips for enhancing intimacy, overcoming common sexual challenges, and sustaining long-term passion.  Gain insights from their combined 50 years of experience in revolutionizing sex coaching, relationships, and intimacy.  Learn about natural methods to boost sexual health, the impact of neurochemistry, and the role of emotional openness in sexual satisfaction.  Whether you're single, in a relationship, or looking to optimize your intimate experiences, this episode provides invaluable knowledge on creating dynamic and fulfilling connections. - Visit https://embodiedlove.love/ - Fol...
2024-09-061h 06The Joe Cohen Show
The Joe Cohen ShowThe Mechanisms of Aging and How To Reduce Your Biological Age | Chris MirabileIn this episode, Joe sits down with Chris Mirabile, founder and CEO of Novos Labs, to explore cutting-edge strategies for reducing your biological age and slowing the pace of aging.  Chris shares his personal journey and the science behind his success, diving into the mechanisms of aging and the powerful supplements that can make a difference.  They discuss the benefits of fisetin, glycine, hyaluronic acid, and more, uncovering how these ingredients contribute to longevity and overall health.  Chris also shares insights into his daily health regimen, the clinical trials backing Novos' products, and the...
2024-09-021h 06The Joe Cohen Show
The Joe Cohen ShowEnhance Sexual Performance and Satisfaction: Discovering The Adamo Method with Molly MaloofIn this episode, Dr. Maloof reveals her biohacking strategies to revolutionize your sex life, just as you would your nutrition and fitness. Discover research-backed practices and expert insights that go beyond the basics, helping you elevate your intimate experiences and achieve a healthier, more fulfilling life. As the founder and CEO of Adamo Bioscience, Molly is at the forefront of bringing modern sex education to couples with a groundbreaking intimacy program developed through a study of the science of love. The Adamo Method is a 9-week program meticulously crafted for couples ready to...
2024-08-231h 09The Joe Cohen Show
The Joe Cohen ShowDr. Gerald Pollack: How to Create The Perfect Water For Optimal Health | Throwback Episode #03This episode was originally published on May 22, 2015. Join Joe in an engaging interview with Dr. Gerald Pollack, a distinguished professor from the University of Washington, as they explore the groundbreaking concept of EZ water, also known as the fourth phase of water.  Discover its unique properties, health benefits, and interaction with factors like infrared light, pressure, and minerals.  The discussion extends to structured water, grounding, and even delves into revolutionary theories such as Rupert Sheldrake's morphic resonance.  Tune in for an insightful journey into water science and its profound implications for bio...
2024-08-161h 45The Joe Cohen Show
The Joe Cohen ShowUnlocking the Secrets of Heart Rate Variability with Dr. Andrew AhnIn this episode, Joe interviews Dr. Andrew Ahn, an internal medicine physician and expert in physiological signal analysis.  The central topic of discussion is Heart Rate Variability (HRV). Dr. Ahn describes various measures of HRV, including time-domain, frequency-domain, and nonlinear analysis. He shares insights into personal HRV tracking and the lifestyle factors that influence it, such as exercise, sleep, and stress.  The conversation delves into the effectiveness of wearable devices for HRV measurement and explores breathing techniques that can improve HRV.  Additionally, Joe and Dr. Ahn discuss the role of genetics in HRV and...
2024-08-0945 minThe Joe Cohen Show
The Joe Cohen ShowDr. Alan Bauman | Understanding Hair Loss, Healthy Hair, and Effective Regrowth StrategiesIn this episode, Joe dives deep into the world of hair loss and hair growth treatments with Dr. Alan Bauman, a leading hair restoration physician.  With over 33,000 patients treated and 12,000 hair transplant procedures performed, Dr. Bauman shares his expertise on various treatments like PRP, FUE, Regenera, and even microneedling.  The discussion covers the effectiveness and applications of these therapies, including the potential and limitations of topical treatments like minoxidil and finasteride.  They also explore the impact of nutrition, lifestyle, and newer regenerative medicine techniques on maintaining and enhancing hair growth.  Joe brin...
2024-08-021h 08The Joe Cohen Show
The Joe Cohen ShowUnlocking Health Secrets with Organic Acids Tests: Elizma Lambert's Expert Insights (Part 3)In this third and final part of our series with Elizma Lambert, we dive deep into the world of biohacking, exploring the latest technology, supplements, and research. Join us as Elizma Lambert shares her expertise on optimizing both body and brain health, providing actionable tips and strategies for achieving peak performance. In this episode, you'll discover: The most effective biohacks for enhancing mental clarity and physical vitality. How to personalize your health regimen for maximum results. Cutting-edge research and resources for staying ahead in the health optimization game. Practical...
2024-07-2636 minThe Joe Cohen Show
The Joe Cohen ShowImprove Your Health With These Organic Acids Markers w/ Elizma Lambert (Part 2)This is the second episode of a three-part series with Elizma Lambert, where we delve into the world of the Organic Acids Test (OAT) and its crucial role in optimizing health. In this episode, Elizma explores an array of biochemical markers, including yeast and fungal indicators, bacterial markers, oxalate metabolites, Candida overgrowth, thyroid function, and mitochondrial efficiency.  Lambert explains how these markers are integral to identifying gut dysbiosis, assessing mitochondrial performance, achieving holistic biochemical balance, and so much more. - Visit https://elizmalambert.com/ - Check out SelfDecode: https://selfdecode.com/
2024-07-1949 minThe Joe Cohen Show
The Joe Cohen ShowDr. Michael Snyder | How To Boost Your Longevity with Precision MedicineIn this episode, we dive deep into the world of precision health with Dr. Michael Snyder, a renowned professor of genetics at Stanford University and the chair of the genetics department.  Join us as Dr. Snyder shares his groundbreaking insights on the latest advancements in precision medicine, biohacking, and personalized healthcare.  Discover how cutting-edge technology, supplements, and genetic research can optimize your longevity and overall wellness.  Tune in to learn how you can leverage precision medicine to enhance your longevity and improve your health. Don't miss out on the transformative potential of these inn...
2024-07-051h 05The Joe Cohen Show
The Joe Cohen ShowBiohacking, Fitness and Longevity with Jean FallacaraIn this episode, Joe speaks with Jean Fallacara, a multifaceted entrepreneur, neuroscientist, and calisthenics enthusiast.  Jean shares insights on how he maintains peak performance through biohacking, focusing on supplements, exercise routines, and meditation practices.  Joe and Jean dive deep into the realms of precision health, genetic testing, and maintaining a balanced, enjoyable lifestyle while pursuing optimal health.  Tune in for an engaging discussion on fitness tips, the importance of diet, and how to transform your health regimen! If you're interested in learning more about how your DNA and genetics affect your hea...
2024-06-1447 minThe Joe Cohen Show
The Joe Cohen ShowHow Proline Can Make You A Hypochondriac | Supplement Deep DiveIn this episode, Joe dives into the complex world of proline supplementation. He discusses the impacts proline has on collagen synthesis, aiming for improved skin health, enhanced wound healing, and better exercise recovery.  However, the journey took an unexpected turn as Joe explains the biomechanics behind why he experienced several side effects such as anxiety, restlessness, and hypochondriac behaviors. Throughout the episode, Joe explores: The intended benefits of proline for collagen synthesis and recovery The biochemical interaction of proline with lysine and vitamin C as per the Linus Pauling p...
2024-06-0712 minThe Joe Cohen Show
The Joe Cohen ShowCan This Outperform Caffeine for Better Focus? | Supplement Deep DiveJoin Joe as he takes a closer look at saffron, a spice revered not just for its flavor but for its impressive health benefits.  In this deep dive, Joe explores how saffron could potentially outshine caffeine in enhancing mental clarity and focus.  This episode goes in-depth on how saffron impacts various aspects of health, from improving sleep quality to reducing gut inflammation and boosting immune function. Discover the comprehensive effects of saffron on: Mental Focus: How saffron compares to caffeine in enhancing cognitive performance. Sleep Quality: The role of sa...
2024-05-3118 minThe Joe Cohen Show
The Joe Cohen ShowDecrease Your Heavy Metals by 75% With This Supplement | Supplement Deep DiveJoin Joe as he delves into his journey with MSM (Methyl Sulfonyl Methane) supplementation, a key to detoxing the body and enhancing recovery.  In this episode, Joe discusses: The Impact of Heavy Metals on Health: Understanding the dangers of heavy metals and the importance of detoxing them from our bodies. MSM as a Detox & Methylation Aid: How MSM supplementation helps clear heavy metals and play a vital role in methylation. Recovery and Resilience Through MSM: How MSM aids in the recovery of tendon and joint injuries, contributing to better exercise outcomes.
2024-05-2424 minThe Joe Cohen Show
The Joe Cohen ShowResistant Starch vs. Ozempic: A Natural Path to Weight Loss and Cognitive Boost | Supplement Deep DiveBuy Jo’s Resistant Starch on Amazon Join Joe as he explores the powerful benefits of resistant starch as a natural alternative to Ozempic.  In this episode, Joe dives into how resistant starch not only supports weight management and cognitive function but also promotes gut health—all without the side effects associated with pharmaceutical options like Ozempic. Joe discusses: Resistant Starch for Health: How this natural supplement enhances the production of butyrate, GLP-1, and how these play significant roles in weight loss, muscle growth, and overall health improvement. Cognitive and M...
2024-05-1717 minThe Joe Cohen Show
The Joe Cohen ShowDr. Ritamarie on Integrating Personalized Health Into Your Daily LifeIn this episode, Joe has an in-depth conversation with Dr. Rita Marie, a licensed doctor of chiropractic and the founder of the Institute of Nutritional Endocrinology, about the importance of personalized healthcare in addressing insulin, thyroid, adrenal, and digestive imbalances through the integration of genetics and lifestyle changes.  Dr. Rita Marie discusses her approach to helping patients by not only looking at conventional lab tests but also incorporating genetics and lifestyle factors such as diet, sleep, and stress management to create a comprehensive health strategy.  She emphasizes the necessity of moving beyond one-size-fits-all solutions to ta...
2024-05-1047 minThe Joe Cohen Show
The Joe Cohen ShowCan AKG Make You Anxious?: The Pros & Cons of This Longevity SupplementIn this episode, Joe dives deep into the effects of megadosing AKG (Alpha Ketoglutarate), a crucial supplement in metabolic pathways and its implications for longevity. Discover the risks and rewards as Joe recounts increasing his AKG intake to 15 times the standard dosage, leading to notable side effects such as enhanced anxiety and sleep issues.  Joe meticulously explains the biochemical transformation of AKG into glutamate and reviews strategies to counteract these negative impacts, including the use of supplements like B6 and Niacin.  He concludes by weighing the pros and cons of AKG. Tune in to...
2024-05-0314 minThe Joe Cohen Show
The Joe Cohen ShowHow Betaine and BHMT Influence Your Methylation | SNPit #19In this episode, we delve into the pivotal role of the BHMT gene within the body's methylation process.  We discuss how the BHMT enzyme is essential for catalyzing a vital reaction that transforms homocysteine into methionine.  Additionally, we cover the importance of betaine in enhancing the methylation cycle. Betaine acts as a methyl donor, particularly in the reaction facilitated by the BHMT enzyme, making it crucial for reducing homocysteine levels and supporting cardiovascular and neurological health. We also explore the complexity of methylation pathways and emphasize the need for a comprehensive evaluation of mu...
2024-04-3005 minThe Joe Cohen Show
The Joe Cohen ShowIs Niacin Killing You?: Breaking Down The New Niacin StudyIn this episode, Joe tackles a controversial new study that suggests even 25 milligrams of niacin could potentially increase the risk of heart disease.  Delving deep into the world of niacin supplementation, Joe discusses how, despite these concerns, niacin offers numerous health benefits, including enhanced cognitive function, better mood, and increased energy levels. Joe draws on personal experiences to compare the negatives against the significant positives of niacin, as he explores niacin's biochemical effects, particularly its interaction with proteins such as 2PY, 4PY, and VCAM1, all linked to cardiovascular health.  Throughout the episode, Joe ex...
2024-04-2627 minThe Joe Cohen Show
The Joe Cohen ShowThe Science of Cannabinoids and the CNR1 Gene | SNPit #18In this episode, we explore the complex interplay between the CNR1 gene, cannabinoid receptors, and cannabis.  Discover the role of the endocannabinoid system in maintaining bodily balance, particularly in brain function, mood regulation, and inflammation response.  We delve deep into how genetic variations in the CNR1 gene can influence the CB1 receptors, and the implications of CB1 receptor function in managing stress, anxiety, and cognitive processes such as memory and decision-making.  Whether you're curious about the science behind getting high or looking for ways to optimize your cannabinoid system through diet and supplements lik...
2024-04-2405 minThe Joe Cohen Show
The Joe Cohen ShowBalance Serotonin and Decrease Anxiety With The HTR1A & HTR2A Genes | SNPit #17In this episode, we explore the crucial role of serotonin in managing anxiety and enhancing mental wellbeing.  Discover how serotonin not only influences mood but also plays a pivotal role in anxiety regulation and mental health.  Learn about the HTR1A and HTR2A genes, which act like switches, controlling the serotonin levels in the brain.  Understanding the SNPs in these genes can provide personal insights into your serotonin activity, offering potential strategies to alleviate anxiety, depression, and other mental health disorders.  The episode further discusses how various serotonin receptors, affected by g...
2024-04-1607 minThe Joe Cohen Show
The Joe Cohen ShowQ&A #03 - Answering Questions About SelfDecodeIn this episode, Joe takes questions from SelfDecode members, answering questions like: What makes SelfDecode different from other DNA companies? How does the recommendations engine work? Can you find out if a certain supplement is right for you? Plus, he shares some of his genetic predispositions and how they correlate with his lab levels! - Check out SelfDecode: https://selfdecode.com/ - Join Joe’s online community: https://thejoecohenshow.com/ 
2024-04-1225 minThe Joe Cohen Show
The Joe Cohen ShowMTHFD1, Choline and Methylation | SNPit #16In this episode, we delve into the critical process of methylation, highlighting its significant impact on health issues ranging from heart disease to mental health and focusing on a lesser known methylation gene - MTHFD1. We focus on the MTHFD1 gene and choline's significance beyond methylfolate and Vitamin B12 for undermethylators.  Discover how MTHFD1 impacts methylation by metabolizing tetrahydrofolate and how choline is important in supplying methyl groups.  We highlight the impact of a negative MTHFD1 variant on choline usage and the potential consequences of choline deficiency, while also stressing the importance of co...
2024-04-0906 minThe Joe Cohen Show
The Joe Cohen ShowDr Jack Kruse On Biohacking Your Water, EMFs, Blue Light, DHA, Cold, Sun and Sleep | Throwback Episode #02This episode was originally published on April 12, 2015. Dr. Jack Kruse and Joe explore unconventional approaches to health through the lens of physics and biochemistry.  They cover topics like the critical roles of mitochondrial function, environmental factors such as EMFs, blue light, and dietary choices on our well-being, and challenge common health paradigms, emphasizing the importance of circadian biology, the effects of cold exposure, water quality, and the necessity of questioning mainstream nutritional advice.  Next, they focus on aligning with nature's design through sunlight exposure, understanding electron flow, optimizing DHA intake, and reducing exposure to...
2024-04-052h 00The Joe Cohen Show
The Joe Cohen ShowDopamine, Serotonin, Norepinephrine, and MAOB | SNPit #15In this episode, we delve into the science behind the MAOB gene and monoamine neurotransmitters.  Join us as we explore the crucial role of dopamine, serotonin, and norepinephrine in regulating mood and cognition.  We dissect the function of the MAOB gene in metabolizing neurotransmitters and discuss the implications of genetic variations on mental health.  From increased breakdown linked to mood disorders to decreased activity associated with elevated neurotransmitter levels, we unravel the complex interplay between genes and mental well-being. If you're interested in learning more about how your DNA and genetics aff...
2024-04-0305 minThe Joe Cohen Show
The Joe Cohen ShowOptimizing Functional Health Markers with The Biohacker Babes: From HRV Optimization to GI MappingIn this episode, Joe dives into the world of personalized wellness with Lauren Sambataro and Renee Belz, known as The Biohacker Babes. With roots in wellness and holistic dentistry, The Biohacker Babes bring their wealth of expertise as health entrepreneurs, nutritional consultants, and holistic lifestyle coaches to the table. In this enlightening conversation, we explore the pivotal role of lab testing in crafting personalized health regimens, emphasizing essential tests such as CBC, CMP, and functional lab tests. The Biohacker Babes also dive into the complexities of hormone regulation, genetic predispositions, and the profound...
2024-03-2957 minThe Joe Cohen Show
The Joe Cohen ShowDopamine & The DRD2 Gene | SNPit #14In this episode of The Joe Cohen Show, we dive deep into the world of dopamine. We'll be focusing on the role of genetics, specifically the DRD2 gene, in regulating dopamine levels and how it affects your brain's reward system, motivation, and susceptibility to addiction. Here's what you can expect to learn: How the DRD2 gene influences dopamine D2 receptors and their impact on pleasure-seeking behaviors. Understanding the variants of the DRD2 gene and its link to dopamine receptor. How genetics can affect motivation, reward processing, and potentially lead...
2024-03-2604 minThe Joe Cohen Show
The Joe Cohen ShowTim Gray, Kris Gethin and Siim Land: Navigating Advanced Health Testing w/ Expert Advice & StrategiesJoin us for an enlightening roundtable discussion featuring health experts Joe Cohen, Kris Gethin, Tim Gray, and Siim Land as they dive deep into the world of health optimization.  In this episode, our expert panel explores a wide range of health tests and biomarkers, from basic to advanced, and what they mean for your health, including VO2 max assessments, heart rate variability, full-body MRI scans, gut microbiome analysis, and food sensitivity testing. We also discuss topics like EMF and heavy metal sensitivity, shedding light on how these factors can impact overall health.  Get ex...
2024-03-221h 21The Joe Cohen Show
The Joe Cohen ShowThe Science of Relationships: A Look at OXTR and Oxytocin | SNPit #13Love is in the air as we dive into the science behind relationships. In this episode, we explore the fascinating world of oxytocin, affectionately known as the "love hormone," and its connection to the OXTR gene. Responsible for encoding the oxytocin receptor, this gene plays a crucial role in shaping our social bonds, empathy levels, and even cognitive abilities. We discuss groundbreaking research, including the 'happy marriage study,' which unveils intriguing insights into how our genetic variations may influence our relationship dynamics. We uncover how oxytocin, influenced by the OXTR gene, extends...
2024-03-1905 minThe Joe Cohen Show
The Joe Cohen ShowMastering Skin Health: Essential Biohacks and Skincare Secrets with Amitay EshelIn this episode, Joe discusses skin health, anti-aging strategies, and the science behind skincare with biohacker and beauty industry leader Amitay Eshel, CEO of Young Goose.  Amitay shares his expertise on improving skin health through a combination of internal health, high-quality skincare products, and biohacking techniques.  The conversation covers topics such as the efficacy of various skincare ingredients, the impact of sun exposure, and innovative approaches to anti-aging.  Amitay also delves into the science of skin renewal, the role of vitamins and metabolites in skin health, and offers practical advice on creating an eff...
2024-03-151h 06The Joe Cohen Show
The Joe Cohen ShowNavigating your Circadian Rhythm, Sleep, and CLOCK Gene | SNPit #12In this episode, we uncover the significance of the CLOCK and PER2 genes, pivotal players in regulating your body's circadian rhythm. Learn how these genes influence your sleep patterns, alertness levels, and even your predisposition to certain health conditions. Discover how variants in the CLOCK gene can impact your circadian rhythm, sleep duration, and daily activity patterns.  Explore the associations between genetic variations in the PER2 gene and your tendency to be an early riser or a night owl, as well as its influence on sleep disorders and mood. If you're interested in l...
2024-03-1204 minThe Joe Cohen Show
The Joe Cohen ShowThe Science of Methylation and MTHFR with Dr. Ben LynchIn this episode, Joe brings on Dr. Ben Lynch - renowned geneticist and author of Dirty Genes - to unreavel the science of methylation, MTHFR, folates, and homocysteine. Dr. Lynch intricately unpacks the complexities of methylation pathways, shedding light on how genetic variations can impact these crucial processes.  Joe and Ben then delve into the specifics of homocysteine metabolism and the role of B vitamins in maintaining optimal levels. They provide invaluable insights into personalized supplements tailored to address individual genetic predispositions and health needs. Explore the latest advancements in methylation a...
2024-03-081h 37The Joe Cohen Show
The Joe Cohen ShowSNPit #11 | A Gene That Affects Longevity More Than Smoking?In this episode of SNPit, we delve into the fascinating world of the FOXO3 gene, a genetic guardian that holds the key to a longer life.  But here's the twist: did you know that certain variants of this gene could impact your lifespan more than smoking a pack of cigarettes every day for 25 years?  We uncover the research behind this startling revelation and discuss the implications for our health and well-being.  Plus, we reveal actionable steps you can take to optimize your FOXO3 gene for better longevity.  If you're interested in lear...
2024-03-0604 minThe Joe Cohen Show
The Joe Cohen ShowA Deep-Dive Into Gut Health And Microbiome With Michael SmithJoe delves deep into the world of biohacking alongside esteemed naturopath Michael Smith.  Drawing on two decades of expertise, Michael shares invaluable insights into optimizing health, particularly focusing on gut health and the microbiome.  From his personal journey to professional practice, Michael discusses the latest advancements in gut health research, tackling issues such as fatigue, autoimmune conditions, and more. Michael shares some practical strategies for enhancing gut health and addressing chronic conditions. Join Joe and Michael as they explore the pivotal role of lifestyle changes, targeted supplements, and personalized DNA data in...
2024-03-0152 minThe Joe Cohen Show
The Joe Cohen ShowTop 6 Health Transformation Tips You Need To HearToday, we're excited to bring you the cream of the crop – the top 6 health advice of Season 5 - that have not only resonated most with our listeners but have the power to transform your approach to health and wellness. These highlights encapsulate the essence of what it means to live well in today's world. Each clip has been handpicked for its impact, insight, and potential to inspire positive change in your life. Whether you're a long-time listener or just joining us, this episode is your gateway to the best health advice we've uncovered in Season 5. ...
2024-02-2355 minThe Joe Cohen Show
The Joe Cohen ShowMaster The 3 Pillars Of Immune HealthGet an in-depth overview of the components of the immune system, learn how to identify when they're compromised, and get insights on how to support them to prepare your body for illness.  Joe discusses the importance of focusing on immune support before illness occurs, diving deep into the roles of mitochondria, extracellular matrix, and inflammation, and how their strengths affects the immune system - sharing key supplements that help optimize each component! - Check out SelfDecode: https://selfdecode.com/ - Join Joe’s online community: https://thejoecohenshow.com/ 
2024-02-1628 minThe Joe Cohen Show
The Joe Cohen ShowSNPit #10 | Understanding Appetite, Emotional Eating, and Fat MetabolismIn this episode, we focus on the FTO gene's pivotal role in fat metabolism, appetite, and weight management.  Get an in-depth analysis of how the FTO gene not only influences body weight and obesity risk but also regulates appetite and fat metabolism, alongside managing emotional eating and hunger levels.  We discuss the gene's connection to weight-related challenges, including its effects on insulin resistance, blood sugar levels, and energy expenditure.  By understanding one’s genetic predispositions, individuals can adopt personalized approaches to diet, lifestyle, and supplementation, turning genetic insights into actionable plans for improving fat m...
2024-02-1405 minThe Joe Cohen Show
The Joe Cohen ShowExploring Rapamycin, Longevity and Healthspan with Dr. Matt Kaeberlein In this episode, Dr. Matt Kaeberlein, CEO of OptiSpan and co-director of the Dog Aging Project, and Joe explore the fascinating realm of rapamycin and its implications for longevity and healthspan. Dr. Kaeberlein delves into the biological mechanisms underlying rapamycin's effects, the best way to take it, and its impact on immune system processes. Gain insights from Dr. Kaeberlein's research on the mTor mechanism and rapamycin, uncovering their promising potential in extending healthspan and enhancing lifespan. Finally, Matt and Joe discuss aging clocks, biomarkers, and microbiome tests, evaluating their significance...
2024-02-091h 08The Joe Cohen Show
The Joe Cohen ShowA Practical Guide to Lab Tests for Optimal HealthDive into the world of lab testing and unlock the secrets to optimal health. In this episode, Joe sheds light on the crucial role lab tests play in understanding our health, cautioning against the limitations of standard tests often offered by conventional medicine.  Delve deep into the realm of comprehensive testing as Joe shares his insights on a variety of essential lab markers, including Complete Metabolic Panel, Complete Blood Count, Thyroid Panel, and Amino Acid Panel, among others.  Learn why these tests are vital for gaining a holistic view of your well-being. ...
2024-02-0247 minThe Joe Cohen Show
The Joe Cohen ShowSNPit #09 | How Your Body Uses Vitamin D & The VDR GeneWe unravel the intricate relationship between sunlight, Vitamin D, and your genetic makeup, as we explore the pivotal role of Vitamin D in optimizing health and well-being. At the heart of this discussion lies the VDR gene, a genetic blueprint responsible for producing the Vitamin D receptor, as we uncover it’s role alongside Vitamin D in the body. We delve into the fascinating journey of Vitamin D synthesis, from sun-kissed skin to the activation of calcitriol, the biologically active form of Vitamin D.  Understanding your unique genetic profile empowers you to make inf...
2024-01-3003 minThe Joe Cohen Show
The Joe Cohen ShowEnergy, Mental Clarity and NAD: Biohacking with James SchmachtenbergerJoin Joe in a conversation with successful biohacker and CEO of Neurohacker Collective, James Schmachtenberger.  James shares his two-decade-long journey with biohacking, focusing on improved energy, cognitive function and how NAD changed his life. Learn about utilizing research, software solutions like genetics and lab tests, lifestyle changes, and supplementation for optimizing your health.  - Use code “SELFDECODE” to get 15% OFF any product at neurohacker.com - Check out SelfDecode: https://selfdecode.com/ - Join Joe’s online community: https://thejoecohenshow.com/  Timestamps: (0:00) - Intro (1:28...
2024-01-261h 12The Joe Cohen Show
The Joe Cohen ShowSNPit #08 | The IL6 Puzzle: Unraveling Genetic Threads of ImmunityEver wondered why some people seem to avoid sickness effortlessly, while others catch every bug in the vicinity? It turns out, luck and genetics may both play a role. In this episode, we uncover the secrets of the IL6 gene, responsible for coding interleukin 6 (IL-6), a crucial immune messenger.  Discover how certain variants of the IL6 gene, such as rs1800795, are linked to higher or lower IL-6 levels, affecting immunity and susceptibility to infections. But the story doesn't end there – we explore other variants like rs1800796, connecting genetic makeup to conditions like acne, lon...
2024-01-2303 minThe Joe Cohen Show
The Joe Cohen ShowBiohacking Longevity: Navigating Lab Tests, Supplements, and Lifestyle for Optimal Aging w/ Michael LustgartenUnlock the secrets to longevity with our deep dive into biohacking, lab tests, and supplements! In this episode, we explore the crucial role of lab markers in longevity, optimal lab test ranges, and associations that impact aging. Dive into the world of supplements, addressing concerns about tolerance and when is the right time to supplement for lifespan. Joe and Michael discuss the Dunedin Pace Test and its significance in aging, while shedding light on the impact of lifestyle changes and immune system health. Going deeper into the science, Michael and Joe analyze mortality risk, liver damage, protein intake, urea...
2024-01-191h 49The Joe Cohen Show
The Joe Cohen ShowSNPit #07 | Can This Gene Help With Your Body’s Detox?This episode explores the transformative potential of the UGT1A1 gene in your body’s ability to detox toxins. Uncover the role of this gene in Glucuronidation, a crucial chemical reaction that enhances the body's ability to detoxify. Learn about the impact of genetic variations which can reduce the activity of the UGT enzyme, hindering the body's detox capabilities. Discover practical solutions to counteract toxic buildup and support the body's natural detoxification processes. This episode unveils the science behind genetic detoxification, providing valuable insights into personalized approaches for optimal health. If yo...
2024-01-1604 minThe Joe Cohen Show
The Joe Cohen ShowHow to Optimize Your MethylationIn this episode, Joe discusses the fascinating topic of methylation and its importance for overall health.  From explaining the tests that can determine if you're an over or under methylator, to providing recommendations on how to support your methylation process, Joe covers everything you need to know.  Discover how genetic variations, such as MTHFR and MTRR, can impact your need for nutrients like folate and B12.  Get insights into specific lab markers and supplements that can help optimize your methylation levels.  Find out how sleep, exercise, stress management, and detoxification play a cr...
2024-01-1231 minThe Joe Cohen Show
The Joe Cohen ShowSNPit #06 | PEMT, Choline, and Cellular HealthJoin us on an exhilarating journey into the intricate world of choline and the PEMT gene. Delve into the significance of choline and how it impacts cellular health, brain function, and beyond, and how PEMT plays a role in choline production. Discover the intricate genetic variants within PEMT, unravelling how certain alleles influence susceptibility to choline deficiency and associated risks. Plus, learn how estrogen stimulation plays a crucial role, posing unique challenges for different demographics. Tune in to 'SNPits' on The Joe Cohen Show to grasp the genetic intricacies impacting our...
2024-01-0905 minThe Joe Cohen Show
The Joe Cohen ShowBoosting Immunity and Biohacking to Prevent Illness with Dr. OzIn this episode, we delve deep into the importance of the immune system and how you can optimize it for peak performance.  Immunity isn't just about avoiding the common cold; it can impact all areas of health, from physical wellness to mental clarity.  Joe, a seasoned biohacker, shares his personal experiences and strategies for ramping up immunity, shedding light on how a data-driven approach can yield significant benefits.  We also explore a comprehensive protocol for when you do get sick, outlining a series of steps incorporating diet changes, specific supplements, and unique lifestyle adj...
2024-01-051h 00The Joe Cohen Show
The Joe Cohen ShowNavigating Your MTHFR Gene: Essential Lab Markers and Ideal Supplements for SupportIn this episode, Joe dives deep into the fascinating world of MTHFR and what you can do if you carry the negative variants! Join us as we unravel the mysteries surrounding these important topic and explore everything you need to know about genetic variations, folate metabolism, and the crucial role of methylation in our bodies.  Joe breaks down the science behind MTHFR, explains how to interpret your genetic results, and shares valuable insights on optimizing your folate levels.  Discover the benefits of methylfolate, explore the connection between homocysteine and methylation, and learn practical ti...
2023-12-2923 minThe Joe Cohen Show
The Joe Cohen ShowSNPit #05 | Do MTR & MTRR Deserve as Much Attention as MTHFR?You’ve probably heard of the hype around MTHFR and how it affects methylation, but what about other genes implicated in the methylation process? In this SNPit the spotlight shifts to MTR and MTRR, and how they can affect levels of homocysteine in the body. Learn all about why homocysteine is important, how genetic variants can affect your levels, and other factors that affect methylation. … Because MTHFR doesn’t tell the whole story. If you're interested in learning more about how your DNA and genetics affect your health, you can: - Check...
2023-12-1505 minThe Joe Cohen Show
The Joe Cohen ShowBiohacking, Longevity, and Optimizing Health with Dr. Darshan ShahIn this episode of the Joe Cohen Show, we welcome Dr. Darshan Shah, a renowned health specialist, surgeon, author, and founder of Next Health. We dive deep into the cutting-edge health optimization methods used at his clinic to extend lifespan and health span. Dr. Shah shares intriguing insights on the role of biohacking, the importance of managing metabolic disease, micronutrient testing, and the function of certain nutrients in our bodies. Throughout the discussion, Joe demonstrates how he uses SelfDecode to analyze his personal health data, illuminating the power of personalized health management. - Follow @darshanshahmd on Instagram
2023-12-0851 minThe Joe Cohen Show
The Joe Cohen ShowThe Power of Neurofeedback: Understanding Brain Waves to Improve Anxiety, Sleep, and Social Skills with Dr. Andrew HillDive deep into the fascinating world of brain health, brain mapping, and the game-changing impact of neurofeedback on anxiety, sleep, executive function, and so much more.  In this episode, Dr. Andrew Hill - a neuroscientist with a Ph.D. in Cognitive Neuroscience from UCLA and is best known as an expert neurofeedback practitioner and brain fitness coach - shares his decades of knowledge to help us understand the power of neurofeedback. Discover the pivotal role of brain mapping in tailoring personalized neurofeedback treatments, how certain brainwaves in different areas of the brain affect your cognition, a...
2023-12-011h 16The Joe Cohen Show
The Joe Cohen ShowMastering Methylation: Understanding MTHFR, Homocysteine, and Folates with Dr. Denise FurnessUnlock the mysteries behind methylation, MTHFR, and homocysteine! Join us as we dive into these widely recognized yet often misunderstood terms that impact heart health, mental well-being, fertility, and more. The surge in popularity around methylation, MTHFR, and homocysteine has led to a barrage of misinformation.  In this enlightening episode, we've invited Dr. Denise Furness, a distinguished molecular geneticist boasting over two decades of expertise in folate nutrigenomics, methylation, and DNA damage. Join us for a wealth of game-changing insights as Denise delves deep into: Understanding methylation's pivotal role in your h...
2023-11-171h 15The Joe Cohen Show
The Joe Cohen ShowSNPit #04 | Unlocking Your Brain's Hidden Potential: The BDNF Gene ExplainedHave you ever wondered if a single gene could hold the key to unlocking your cognitive potential, or perhaps, be the culprit behind those moments of brain fog? Discover the fascinating world of the BDNF gene in this episode of SNPits.  Explore how your genetic makeup can impact your cognitive function and memory and uncover the association between BDNF variants and brain health.  Plus, learn how to naturally boost your BDNF levels for improved learning and mental performance. If you're interested in learning more about how your DNA and genetics affect yo...
2023-10-2004 minThe Joe Cohen Show
The Joe Cohen ShowSNPit #03 | How Much Does The ApoE Gene REALLY Affect Alzheimer’s?Is the ApoE gene solely a predictor of cognitive decline, or is it just one piece of a larger, more intricate puzzle? In today's episode, we focus on the ApoE gene, a genetic player that’s most notoriously linked to Alzheimer's Disease. Julia dives deep into the three major variants called E2, E3, and E4, discussing how they change the shape of the ApoE protein and impact how well it functions. she  also opens up the curtain on other health issues that can be caused by the ApoE gene —impacting your cardiovascular health, your...
2023-09-1505 minThe Joe Cohen Show
The Joe Cohen ShowUncover the Secrets of Supplements: A Deep Dive Into The Science Behind Dietary Supplements with Emiel BakkerWhy are there so many different versions of the same supplement? Is it all just a marketing ploy, or do they all have different effects on your health? In this episode, Emiel Bakker from Nootropics Depot comes on to dive into the complex world of dietary supplements, where not all products are created equal. He gives us an inside look at the science behind developing a supplement, from deciding on an extraction method to choosing between a fruiting body vs. mycelium. We uncover the nuanced factors that influence the efficacy and effects of...
2023-09-081h 33The Joe Cohen Show
The Joe Cohen ShowSNPit #02 | Does the COMT Gene Make You A Warrior Or A Worrier?Welcome back to SNPits, a short form series helping you decode your DNA, one gene at a time.  In this episode, we delve into the fascinating world of the COMT gene, commonly dubbed the "Warrior/Worrier" gene. We unpack the science behind this gene's influence on stress regulation, emotional resilience, and even cognitive function.  Is the "Warrior/Worrier" label an oversimplification, or does it offer a genuine glimpse into our genetic predisposition? Whether you're well-versed in genetics or just taking your first steps into this fascinating realm, today's episode promises to be...
2023-08-2504 minThe Joe Cohen Show
The Joe Cohen ShowHow To Use Genetics, Labs, and Lifestyle to Tackle Any Health Issue with Dr. Greg NacarelliJoin us as we dive deep into the world of genomics, nutrition, and precision health with Dr. Greg Nacarelli, a leading expert in naturopathic medicine and genetics.  Dr. Nacarelli delves into the intricate interplay of genetics, environment, and lifestyle on our health, explaining why personalizing health care is the future. Greg touches on the value of understanding individual genetic profiles and how this can be utilized for personalized nutrition and health coaching.  With extensive academic qualifications and years of experience working with SelfDecode, Greg brings a unique blend of expertise to the table.  ...
2023-08-1840 minThe Joe Cohen Show
The Joe Cohen ShowSNPit #01 | The MTHFR Debate: Overhyped or Underestimated?Welcome to SNPits, a new, short-form podcast series that takes you on a deep dive into specific genes, unraveling the science behind them and their impact on health.  In this episode, we tackle the MTHFR gene and its rise to fame. We explore how 'typos' in our genes, known as SNPs, influence our health, and dive into the debate surrounding one of the most studied genes in the world.  Is the MTHFR gene truly a culprit in conditions like heart disease and chronic fatigue, or is it a scapegoat?  Join us as...
2023-08-0404 minThe Joe Cohen Show
The Joe Cohen ShowQ&A #01 - Understanding Anxiety: The Genetic Connection and Holistic RemediesIs anxiety truly genetic? How do our genes and environment shape our response to stress? Are we all experiencing the world differently based on our unique biochemical make-up?  In this episode, Joe and Dr. Greg (SelfDecode Health Expert) dive deep into the realm of anxiety, answering questions from the SelfDecode community and unmasking the role our brain's biochemistry plays in the expression of anxiety. Joe and Greg discuss the role of mental health in overall wellness and highlight specific genes that you can look at to potentially help you get rid of anxiety. T...
2023-07-1450 minThe Joe Cohen Show
The Joe Cohen ShowDNA Secrets, Gut Health, and the Hidden Benefits of A Holistic Approach with Dr. Anil BajnathWhat’s the difference between genomics and genetics? How important is it to understand your genes when looking at optimizing your health? In this episode, Dr. Anil Bajnath and Joe delve into the world of DNA and their impact on our health. Dr. Bajnath breaks down complex health science concepts in a way that's easy to understand, while sharing his unique approach to healthcare. Some highlights of the episode include: ✔️ Understanding the difference between genomics (the study of all genes in our body) and genetics (the study of inh...
2023-07-071h 35The Joe Cohen Show
The Joe Cohen ShowHow To Get Rid Of Your Food Sensitivities And Eat Anything You Want | Joe's RegimenDo you ever feel like you're walking on a tightrope, unsure of what foods might trigger an unwanted reaction?  Well, you're not alone.  Food sensitivities are more common than ever, and they can cause a whole host of issues ranging from digestive discomfort to brain fog. After years of research and experimentation, and with the help of SelfDecode, Joe found what he think is a break through in reversing food sensitivities. Now, he can eat things that he never thought possible a few years ag...
2023-04-2847 minThe Joe Cohen Show
The Joe Cohen ShowBest of The Joe Cohen Show: Top 10 Moments of Season 2To celebrate the end of Season 2, we’ve gathered the top 10 moments of The Joe Cohen Show and compiled them into a single podcast episode! These moments were voted on by Joe, employees of SelfDecode, and listeners of The Joe Cohen Show. It includes clips filled with valuable knowledge on different health topics and actionable takeaways that you can implement in your daily life. Full The Joe Cohen Show Episode links: Stacy Sims Dominik Nischwitz Richard Miller Molly Maloof Chris Ma...
2023-04-1456 minThe Joe Cohen Show
The Joe Cohen ShowHealth Analysis Series #02 | How To Discover The Best Diet & Supplements For Your Body with Briana TherouxIn our Health Analysis Series, Joe Cohen, expert biohacker and founder of SelfDecode, brings on a guest, and together they utilize the power of DNA and labs to assess, discuss, and recommend ways to further optimize their health. Our guest today is Briana Theroux, a health professional certified by the Institute for the Psychology of Eating who has over a decade of experience biohacking her health. In episode 2 of this 2 part series, Joe and Briana analyze her DNA results on SelfDecode, as well as her current and past lab...
2023-03-311h 03The Joe Cohen Show
The Joe Cohen ShowHealth Analysis Series #01 | How To Navigate Your Health History, DNA, and Labs with Briana TherouxIn our Health Analysis Series, Joe Cohen, expert biohacker and founder of SelfDecode, brings on a guest, and together they utilize the power of DNA and labs to assess, discuss, and recommend ways to further optimize their health. Our guest today is Briana Theroux, a health professional certified by the Institute for the Psychology of Eating who has over a decade of experience biohacking her health. In episode 1 of this 2 part series, Briana goes over her health history, discusses some of the game-changing supplements and lifestyle changes she has done to overcome her health issues...
2023-03-2459 minThe Joe Cohen Show
The Joe Cohen ShowNathan Price: Chronic Diseases, Preventative Care & Polygenic Risk Scores | Episode 08Have you heard of scientific wellness? In this episode, Nathan Price and Joe discuss whether the conventional approach of using pharmaceuticals to treat chronic diseases is effective, or if a preventative approach to complex conditions such as cardiovascular disease and Alzheimer’s is the best choice. Nathan explains how genes can help predict the success of lifestyle-based interventions and talks about the accuracy of polygenic risk scores vs single variants for disease prediction, and how genetics can be used in healthcare. Nathan and Joe also talk about nicotinamide mononucleotide (NMN), nicotinamide riboside (NR), DHEA, and ot...
2022-11-1152 minThe Joe Cohen Show
The Joe Cohen ShowTim Gray: Sleep, Psychedelics & Methylene Blue | Episode 07Should you be scared of psychedelics? In this episode, Tim Gray and Joe talk about how to get more REM and deep sleep, and Tim discusses his experience with methylene blue. They talk about the pros and cons of alcohol and their experience with different psychedelics. Tim shares his experience with conventional medicine, the top things he’s trying to optimize in his health and his strategies for kidney health, gut health, and more. He talks about how he used to track 35 biomarkers every day, and which ones he still continues to monitor. They discuss me...
2022-11-0458 minThe Joe Cohen Show
The Joe Cohen ShowShawn Wells: All About Supplements & Mitochondrial Health | Episode 06Are supplements a waste of time and money? In this episode, Shawn Wells and Joe discuss whether taking supplements every day is bad for your health, and Joe shares the one time a supplement caused his liver enzymes to spike (it’s not what you’d expect!). Shawn talks about the problem with certain supplement companies and lets you in on important things to look out for when choosing a supplement. They talk about all kinds of supplements, including lipoic acid, dihydroberberine, paraxanthine, ergothioneine, NAD, and more, discussing their effects, dosages, and how they work in the body...
2022-10-281h 31The Joe Cohen Show
The Joe Cohen ShowLucas Aoun: Nootropics, Dopamine & Testosterone | Episode 05Do supplements work the same for everyone? In this episode, Lucas Aoun shares his favorite supplements to improve cognitive function and focus, and he and Joe dig deep into how these compounds work in the body, discussing the research, dosages, and what to look out for. They discuss dopamine and the mechanisms behind dopamine supplements and share their different experiences experimenting with supplements. Plus, listen to the benefits of increasing dopamine levels steadily vs taking supplements that cause a spike. Lucas and Joe also talk about how to optimize testosterone levels, what causes low testosterone...
2022-10-2153 minThe Joe Cohen Show
The Joe Cohen ShowKatie Wells: Intermittent Fasting, Diet & Optimal Labs | Episode 04Low carb? Keto? Low fat? Fasting? In this episode, Katie Wells and Joe talk about her experience with dieting, some of the benefits she gets from intermittent fasting, and they discuss the controversial topic of cholesterol (spoiler: lower is not necessarily better). Katie shares some of her favorite health hacks, and they talk about how genetics can influence a person’s health and how to use this information to live optimally. They also discuss which and how to track labs, the importance of optimal vs normal ranges, and what Katie does to hack her sleep & mood. ...
2022-10-1345 minThe Joe Cohen Show
The Joe Cohen ShowSiim Land: How To Lower Cholesterol & Improve Longevity | Episode 03Is high cholesterol really bad for you? In this episode, Joe and Siim Land discuss what causes high cholesterol, which biomarkers to track for longevity, and the biggest mistake people make when trying to lose weight. Siim shares one surprising mineral that can help lower cholesterol and talks about how intermittent fasting helps his mental & physical performance. Then, Siim and Joe discuss a top supplement for longevity and healthspan. Siim Land is a renowned public speaker and expert in biohacking, health optimization, and overall performance optimization. He is also the author of Metabolic Autophagy and...
2022-10-0651 minThe Joe Cohen Show
The Joe Cohen ShowTeemu Arina: Biohacking Your Brain & Body | Episode 02Kiwi as a biohack for sleep? Bet you didn’t know that one! In this episode, Joe and Teemu Arina talk all about biohacking your sleep, low & high HRV ranges, why heart rate variability is important for your overall health, and discuss some of Teemu’s favorite biohacks for the body & brain. Teemu tells Joe why he got into biohacking, his secret to handling stress, and what he thinks is the best approach to optimizing his mental and physical performance. He also gives you a glimpse of what his supplement stack looks like and lets you in on o...
2022-09-2647 minThe Joe Cohen Show
The Joe Cohen ShowDr. Mercola: Vitamin D, Linoleic Acid & Hacking Your Diet | Episode 01Are EMFs harmful? Should you wear sunscreen? In this episode, Joe and Dr. Joseph Mercola discuss these and other controversial topics within the health industry. Dive deep into the importance of sun exposure (it’s not just vitamin D), vegetable oils, and learn valuable insights to hack your diet. Dr. Mercola shares his secret for better vitamin D levels, discusses the problems with linoleic acid and which foods to avoid, and talks about the one supplement he hasn’t taken in 15 years. Plus, listen to the top mistakes people make when trying to biohack their health. Dr...
2022-09-2646 min