Shows
Skinfluenced - The Skin PodcastAtopic Dermatitis Breakthrough: Precision Treatment and the Promise of AdvanceAD-Tx™Disclaimer: This podcast is not sponsored by or associated with any of the products mentioned in today's episode.Episode 15 Drop: Atopic Dermatitis Breakthrough: Precision Treatment and the Promise of AdvanceAD-Tx™In this episode of Skinfluenced: The Skin Podcast, we explore a groundbreaking advancement in the management of moderate-to-severe atopic dermatitis (AD). Castle Biosciences’ new AdvanceAD-Tx™ test, launched THIS MONTH, introduces precision medicine to dermatology with a 487-gene expression profile (GEP) that decodes each patient’s unique immune biology. By classifying results into different profile groups, clinicians can now identify which pa...
2025-11-1113 min
Skinfluenced - The Skin PodcastPress Release: Libtayo (Cemiplimab) Approved as First Adjuvant Immunotherapy for High-Risk cSCCDisclaimer: This podcast is not sponsored by or associated with any of the products mentioned in today's episode.In this episode of Skinfluenced: The Skin Podcast, we break down the FDA’s recent approval of Libtayo® (Cemiplimab-rwlc) as the first and only adjuvant immunotherapy for patients with high-risk cutaneous squamous cell carcinoma (cSCC) following surgery and radiation.Join us as we discuss:🧬 The pivotal trial showing improved disease-free survival in high-risk cSCC💉 The evolving role of PD-1 blockade in post-surgical skin cancer management🧠 How this approval changes the treatment landscape fo...
2025-10-2314 min
Skinfluenced - The Skin PodcastPress Release: Zoryve (roflumilast) 0.05% Cream Approved for Atopic Dermatitis in Ages 2-5Disclaimer: This podcast is not sponsored by or associated with any of the products mentioned in today's episode.In this episode of Skinfluenced: The Skin Podcast, we break down the FDA’s latest approval of ZORYVE® (roflumilast) Cream 0.05%, marking a new topical treatment option for young children living with atopic dermatitis.Join us as we discuss:🌿 Clinical trial data showing safety and efficacy in patients aged 2–5 years💊 How PDE-4 inhibition with roflumilast differs from current treatment options🧴 What this means for real-world management of pediatric eczema
2025-10-0815 min
Skinfluenced - The Skin PodcastPress Release: FDA Approves Remibrutinib (Rhapsido) for Chronic Spontaneous UrticariaDisclaimer: This podcast is not sponsored by or associated with any of the products mentioned in today’s episode.In this episode of Skinfluenced: The Skin Podcast, we review the FDA’s September 30, 2025 approval of remibrutinib (Rhapsido, Novartis), the first oral BTK inhibitor indicated for chronic spontaneous urticaria (CSU). We’ll walk through the press releases, clinical trial data, and recent publications highlighting its efficacy, safety, and potential impact on treatment pathways for CSU.Link to Source(s):The American Journal of Managed Care (AJMC). FDA Approves Remibrutinib for Chronic Sponta...
2025-10-0213 min
Skinfluenced - The Skin PodcastPress Release: Opzelura (ruxolitinib) 2% Cream Approved for Atopic Dermatitis in Ages 2 and UpDisclaimer: This podcast is not sponsored by or associated with any of the products mentioned in today's episode.In this episode of Skinfluenced: The Skin Podcast, we review the brand new FDA approval of Opzelura® (ruxolitinib) cream 1.5% for children ages 2 and up with atopic dermatitis. This marks a major step forward in pediatric dermatology, offering the first topical JAK inhibitor option for younger patients with mild-to-moderate AD who need more than topical steroids or topical calcineurin inhibitors.We’ll discuss the clinical trial data from the TRuE-AD program, safety con...
2025-09-2214 min
Skinfluenced - The Skin Podcast2025 Updated Guidelines of Care for the Management of Atopic Dermatitis in AdultsDisclaimer: This podcast is not sponsored by or associated with any of the products mentioned in today's episode.In this episode of Skinfluenced: The Skin Podcast, we’re breaking down the American Academy of Dermatology’s June 2025 focused update on the management of Atopic Dermatitis (AD) in adults.We’ll highlight how to integrate the latest high-quality evidence into practice, including new FDA-approved therapies that are reshaping the treatment landscape. From tapinarof and roflumilast creams, to biologics like lebrikizumab and nemolizumab, we review the data behind their efficacy and safety, drawn from multip...
2025-09-1517 min
Skinfluenced - The Skin PodcastJust Released! Is PDGF Safe?Disclaimer: This podcast is not sponsored by or associated with any of the products mentioned in today's episode.In this episode of Skinfluenced: The Skin Podcast, we have a brand new article to report on. Just a few days ago, a review of the safety of Platelet-Derived Growth Factor (PDGF) was released. Tune in to learn all about this topic of immense interest recently, as well as it’s importance in aesthetic and regenerative medicine.This white paper highlights over 25 years of extensive safety research, discussing the rhPDGF-bb safety profile and tr...
2025-09-0918 min
Skinfluenced - The Skin PodcastPress Release: Wegovy (Semaglutide) now approved for MASHDisclaimer: This podcast is not sponsored by or associated with any of the products mentioned in today's episode.In this episode of Skinfluenced: The Skin Podcast, we take a break from only skin diseases, and delve into our wellness side to take a look into some ground breaking research shaping the understanding and treatment of the newest GLP-1 indication: metabolic dysfunction–associated steatohepatitis (MASH). Join us as we dive into the groundbreaking developments surrounding semaglutide, a glucagon-like peptide-1 (GLP-1) receptor agonist, and its expanding therapeutic potential from upcoming FDA approvals to emerging pharmacologic strategies, th...
2025-08-3112 min
Skinfluenced - The Skin PodcastPDGF: What is it? How is PDGF transforming aesthetics?Disclaimer: This podcast is not sponsored by or associated with any of the products mentioned in today's episode.In this episode of Skinfluenced: The Skin Podcast, join us for an insightful episode exploring Platelet-Derived Growth Factor (PDGF), a revolutionary bio-engineered growth factor that is changing the landscape of aesthetic medicine as we know it. Tune in to discover why PDGF is considered the next frontier in regenerative aesthetics, poised to revolutionize cosmetic medicine and help patients achieve remarkable, long-lasting rejuvenation.In this episode, learn about PDGF's widespread uses, from topical application with microneedling and post-laser...
2025-08-2416 min
Skinfluenced - The Skin PodcastShingles, Sun Damage, and the Skin’s Microbiome—What’s the Link?Disclaimer: This podcast is not sponsored by or associated with any of the products mentioned in today's episode.In this episode of Skinfluenced: The Skin Podcast, learn how sun damage, known as ultraviolet radiation (“UVR”), significantly influences the composition of the skin microbiome and is known to modulate the immune system, potentially leading to immunosuppression. Tune in to learn how this UV-induced immune suppression is correlated with seasonal increases in herpes zoster (shingles) cases. Link to Source(s):American Journal of Epidemiology (2021): Association of Sunburn With Increased Risk of Herp...
2025-08-1709 min
Skinfluenced - The Skin PodcastA Breakthrough in Dermatology: Anzupgo (Delgocitinib) Cream 2% FDA Approved Topical for Chronic Hand EczemaDisclaimer: This podcast is not sponsored by or associated with any of the products mentioned in today's episode.In this episode of Skinfluenced: The Skin Podcast, we break down the recent FDA approval of Anzupgo (delgocitinib) cream 2%, the first and only topical prescription treatment approved in the U.S. specifically for moderate to severe chronic hand eczema (CHE) in adults. We cover what CHE is, how it impacts patients, why this approval is so significant, and the science behind this non-steroidal topical JAK inhibitor.We also explore insights from the DELTA 1 and DELTA 2 phase 3 trials...
2025-08-1016 min
Skinfluenced - The Skin PodcastBreaking News! FDA Admits They Were Wrong About HRTDisclaimer: This podcast is not sponsored by or associated with any of the products mentioned in today's episode.In this episode of Skinfluenced: The Skin Podcast, we take a closer look at brand new statements released from the FDA discussing hormone replacement therapy (HRT) and how WRONG the FDA and all of medicine was for over 20 years! Our hormones affect aging and our skin in so many ways, these new changes will be revolutionary for the field of medicine and health!Link to Source(s):FDA Expert...
2025-08-0313 min
Skinfluenced - The Skin PodcastNavigating Chronic Hand EczemaDisclaimer: This podcast is not sponsored by or associated with any of the products mentioned in today's episode.In this episode of Skinfluenced: The Skin Podcast, we’re shining a spotlight on Chronic Hand Eczema (CHE). With the recent approval the first topical treatment for moderate to severe chronic hand eczema, we want to brush everyone up on CHE.Tune in to discover how this new medication, a topical Janus kinase (JAK) inhibitor, performs against placebo in improving chronic hand eczema. We discuss the clinical benefits, safety profile, and what this means for patients struggling wi...
2025-08-0223 min
Skinfluenced - The Skin PodcastPress Release: Novel New Oral Treatment Option for Plaque PsoriasisDisclaimer: This podcast is not sponsored by or associated with any of the products mentioned in today's episode.In this episode of Skinfluenced: The Skin Podcast, we review Johnson & Johnson’s recent announcement seeking FDA approval for Icotrokinra — a promising new oral medication designed to revolutionize treatment for adults and adolescents with active, moderate-to-severe Plaque Psoriasis.Tune in to learn how this novel oral IL-23 medication works, its potential to offer a novel approach in managing inflammation and safety data, and what this could mean for patients struggling with moderate-to-severe plaque psoriasis who need new trea...
2025-08-0110 min
Skinfluenced - The Skin PodcastCan TSC Calm Retinoid Irritation? A Deep Dive into the 2025 Pilot StudyDisclaimer: This podcast is not sponsored by or associated with any of the products mentioned in today's episode.In this episode of Skinfluenced: The Skin Podcast, we take a closer look at a newly published pilot study from the Journal of Cosmetic Dermatology (Feb 2025) that explores whether Tetramethylhexadecenyl Succinoyl Cysteine (TSC) — the active ingredient in Epicutis’ Lipid Serum — can help reduce the irritation commonly associated with tretinoin use.Tune in to find out what happens when TSC is used in conjunction with tretinoin, and result are seen within just five days! The findings raise interesting questi...
2025-07-2810 min