Shows
Ask Stago (english version)S5E6 - Improving your lab productivity with the STA Workcell MaxWelcome to Ask Stago, the Podcast dedicated to provide expert answers to your expert questions in coagulation.
In today’s episode, Emily Pullen, North America Product Manager, will tell us more about Stago solution to improve lab productivity with the STA Workcell Max.
Literature sources:
https://www.stago.com/products-services/max-generation-analysers/sta-workcell-max/
bff1a8c242e6f9d3b66c957e1422457b
Content is scientific and technical in nature. It is intended as an educational tool for laboratory professionals and topics discussed are not intended as recommendations or as commentary on app...2025-03-2611 min
Ask Stago (english version)S5E5 - Clinical Significance of Fibrin MonomersWelcome to Ask Stago, The Podcast dedicated to provide expert answers to your expert questions in coagulation.
In today’s episode, our guest Dr. Refaai will help us understand the formation and function of fibrin monomers (FM) in hemostasis, highlighting their crucial role in coagulation and clot formation and the need for more prospective studies to validate this assay for clinical indications such as DIC, VTE and cancer.
Literature sources:
Refaai M.A. (2018) The Clinical Significance of Fibrin Monomers. Thromb Haemost, 118, 1856.
Content is scientific and technical in nature. It is intended as an edu...2024-12-1612 min
Ask Stago (english version)S5E4 - MyOptiLab, Stago's Workflow Audit Service for Optimized EfficiencyWelcome to Ask Stago, the Podcast dedicated to provide expert answers to your expert questions in coagulation.
In today’s episode, Anne-Cécile Ortega will further explain what a MyOptiLab audit is — a service offered by Stago that involves a comprehensive workflow study using the Lean Six Sigma methodology. This audit is designed to help laboratories enhance their efficiency by identifying areas for improvement and optimizing processes.
Literature sources:
Bhat, R., & Wagh, P. (2013). "Application of Six Sigma methodology in clinical diagnostic laboratories: A case study." International Journal of Scientific and Research Publications*, 3(7), 1-6.
Goh, T. N...2024-11-2810 min
🇫🇷 Ask Stago (version française)🇫🇷 S4E4 - La fibrinolyse : la phase souvent oubliée de l’hémostaseBienvenue chez « Ask Stago », le Podcast fournissant des réponses d'experts à vos questions d'experts en hémostase.
Dans l'épisode d'aujourd'hui, Tarik Bouriche, Responsable des pôles hémostase et hématologie auprès de la R&D chez BioCytex, nous expliquera combien la fibrinolyse est importante pour l’ensemble du phénomène d’hémostase, et comment l’activité fibrinolytique d’un échantillon doit être évaluée et, parfois, suivie.
Comme toujours n’hésitez pas à nous poser vos questions à ask@stago.com et nous serons heureux d’y répondre
Pour en savoir plus :
Podcast...2024-09-1909 min
Ask Stago (english version)S5E3 - What are microvesicles, their importance in coagulation and how to analyze them?Welcome to Ask Stago, The Podcast dedicated to provide expert answers to your expert questions in coagulation.
In today’s episode, Karine Carrière will explain further what are microvesicles, their importance in coagulation and how to analyze them.
Literature sources:
[Tesselaar et al.], [Lacroix et al.] [Faille et al.] [Mullier et al.] Vallier et al.] . [Nieuwland et al.]
Kim HK, Song KS, Park YS, Kang YH, Lw YJ, Lw KR, et al.
Elevated levels of circulating platelet microparticles, VEGF, 11-6 and
FiANTES in patients Wlth gastrlc cancer. possible mle of a metastasis
predlotor. Eur J...2024-06-0410 min
🇫🇷 Ask Stago (version française)🇫🇷 S4E3 - Le parallélisme des droites pour le dosage des facteursBienvenue chez « Ask Stago », le Podcast fournissant des réponses d'experts à vos questions d'experts en hémostase.
Dans l'épisode d'aujourd'hui, Caroline Gavois, Responsable développement des services, nous aide à mieux comprendre le but et les bénéfices sur le plan clinique du parallélisme des droites pour le dosage des facteurs.
Comme toujours n’hésitez pas à nous poser vos questions à ask@stago.com et nous serons heureux d’y répondre.
Pour en savoir plus :
Podcasts précédents :
S1E10 – How to be more productive (part 1): implementation of a rules en...2024-05-1612 min
Ask Stago (english version)S5E2 - Living with a rare blood clotting disorder, Hemophilia C: an interview with Joseph BautistaWelcome to Ask Stago, the Podcast dedicated to provide expert answers to your expert questions in coagulation.
This month we meet Joseph Bautista, is a 37 year old US man living with a rare clotting disorder, a Factor XI deficiency otherwise known as Hemophilia C. His journey so far has not been an easy one but by educating himself and advocating for the best care he is living a full and healthy life working as a data architect in the IT sector. Its an inspiring and reassuring story for anyone facing a rare bleeding disorder diagnosis & proves the...2024-05-0714 min
Ask Stago (english version)S5E1 - What is new in ISO 15189:2022?Welcome to Ask Stago, The Podcast dedicated to provide expert answers to your expert questions in coagulation.
In today’s episode, our guest Evelyne Escarmant will help us to understand what is behind the recent update of ISO 15189 and what it means for us as manufacturers and indeed the clinical laboratory
Literature sources:
ISO 15189; Medical laboratories – Requirements for quality and competence
Content is scientific and technical in nature. It is intended as an educational tool for laboratory professionals and topics discussed are not intended as recommendations or as commentary on appropriate clinic...2024-04-0211 min
🇫🇷 Ask Stago (version française)🇫🇷 S4E2 - L’hémostase chez la population pédiatrique : Est-ce que les enfants sont des « petits adultes »?Bienvenue chez « Ask Stago », le Podcast fournissant des réponses d'experts à vos questions d'experts en hémostase.
Dans l'épisode d'aujourd'hui, notre invité François Depasse nous expliquera les particularités de la thrombose et de l'hémostase dans la population pédiatrique, et comment gérer les échantillons de patients pédiatriques dans le laboratoire clinique.
Pour en savoir plus :
Liens vers les épisodes précédents :
🇫🇷 S2E2 - Comment déterminer son intervalle de référence ?
🇫🇷 S2E9 - Le B.A.BA du prélèvement sanguin pour l’hémostase
Littératur...2024-03-2112 min
🇫🇷 Ask Stago (version française)🇫🇷 S4E1 - L’importance du FibrinogèneBienvenue chez « Ask Stago », le Podcast fournissant des réponses d'expert à vos questions d'expert en hémostase.
Dans l’épisode d’aujourd’hui, Florence Crépet Manager R&D, nous parlera du dosage du fibrinogène.
Comme d’habitude, n’hésitez pas à nous envoyer vos questions sur Ask@stago.com, nous serons ravis d’y répondre.
Pour en savoir plus :
Références bibliographiques :
Miesbach W, Schenk J, Alesci S, Lindhoff-Last E, Comparison of the fibrinogen Clauss assay and the fibrinogen PT derived method in patients with dysfibrinogenemia .Thromb Res. 2010; 126(6): e42...2024-01-1811 min
🇫🇷 Ask Stago (version française)🇫🇷 S3E12 - IVDR : Quels enjeux pour les fabricants du diagnostic in vitro et les laboratoires ?Bienvenue chez « Ask Stago », le Podcast fournissant des réponses d'expert à vos questions d'expert en hémostase.
Dans l'épisode d'aujourd'hui, Sophie Réhault, Directrice Market Access, nous donnera les explications de ce que contient la nouvelle réglementation européenne pour les dispositifs médicaux de diagnostic in vitro, et ce que cela implique pour les fabricants comme pour les laboratoires cliniques.
Comme toujours n’hésitez pas à nous poser vos questions à ask@stago.com et nous serons heureux d’y répondre.
Pour en savoir plus :
Podcast
Ask Stago FR saison 3...2024-01-1611 min
🇫🇷 Ask Stago (version française)🇫🇷 S3E11 - Démystification de l’agrégation plaquettaireBienvenue chez « Ask Stago », le Podcast fournissant des réponses d'expert à vos questions d'expert en hémostase.
Dans l'épisode d'aujourd'hui, notre invitée Karine Carrière expliquera plus en détail ce qu'est l'agrégation plaquettaire, comment la mesurer et dans quelles indications elle est utilisée.
Comme toujours, n’hésitez pas à nous poser vos questions à ask@stago.com et nous serons heureux d’y répondre.
Pour en savoir plus :
Littérature :
Born GVR. Aggregation of blood platelets by adenosine disphosphate and its reversal. Nature 1962; 194: 927 – 929.
O’Brien JR. Platelet aggregation. II...2023-11-1611 min
🇫🇷 Ask Stago (version française)🇫🇷 S3E10 - L’évaluation externe de la qualitéBienvenue chez « Ask Stago », le Podcast fournissant des réponses d'expert à vos questions d'expert en hémostase.
Dans l'épisode d'aujourd'hui, notre invité parle avec nous de l’EEQ et son intérêt pour que le laboratoire puisse assurer la qualité de son résultat.
Comme toujours n’hésitez pas à nous poser vos questions à ask@stago.com et nous serons heureux d’y répondre
Pour en savoir plus :
Liens vers les épisodes précédents :
Ask Stago FR saison 1 épisode 1: Différencier le contrôle interne de qualité externalisé et l’évaluati...2023-10-1906 min
🇫🇷 Ask Stago (version française)🇫🇷 S3E9-Comment établir les valeurs de références de contrôle qualité ?Bienvenue chez « Ask Stago », le podcast dédié à fournir des réponses d'experts à vos questions d'experts en hémostase.
Dans notre épisode d’aujourd’hui, notre experte Madame Petitjean, Biologiste médical au pôle onco-hémato Chez Cerba, nous parlera de la démarche à suivre pour la détermination des fourchettes des CQ.
Comme d’habitude, n’oubliez pas de nous envoyer vos questions sur Ask@stago.com, nous serons ravis d’y répondre !
Pour en savoir plus :
Liens vers les épisodes précédents :
S1E4 Comment bien déterminer son temps témoin de Pro...2023-09-2109 min
🇫🇷 Ask Stago (version française)🇫🇷 S3E8 - Démystifier l’incertitude de mesureBienvenue chez « Ask Stago », le podcast dédié à fournir des réponses d'experts à vos questions d'experts en hémostase.
Dans l'épisode d'aujourd'hui, Pascal Morer, Manager support scientifique et Qualiris, nous aide à comprendre comment on détermine l’incertitude de mesure et comment on l’utilise.
Comme toujours n’hésitez pas à nous poser vos questions à ask@stago.com et nous serons heureux d’y répondre
Pour en savoir plus :
Littérature :
ISO/TS 20914: 2019 Laboratoires de biologie médicale – recommandations pratiques pour l’estimation de l’incertitude de mesure
ISO 15189:2022 Laboratoires de biologi...2023-08-1712 min
🇫🇷 Ask Stago (version française)🇫🇷 S3E7 - Le TCA un test, plusieurs objectifsBienvenue chez « Ask Stago », le podcast dédié à fournir des réponses d'experts à vos questions d'experts en hémostase.
Dans notre épisode aujourd’hui notre experte Céline Ayel, nous parlera du test TCA.
Pour en savoir plus :
Littérature :
Toulon, P., Eloit, Y., Smahi, M., Sigaud, C., Jambou, D., Fischer, F. and Appert‐Flory, A. (2016), In vitro sensitivity of different activated partial thromboplastin time reagents to mild clotting factor deficiencies. Int. Jnl. Lab. Hem., 38: 389-396. https://doi.org/10.1111/ijlh.12499
CLSI One-stage Prothrombin Time (PT) test and Activated Partial Thromboplastin Time (APTT) test; Approved guidelin...2023-07-2010 min
🇫🇷 Ask Stago (version française)🇫🇷 S3E6 - Détermination des niveaux de facteurs en hémophilieBienvenue chez « Ask Stago », le podcast dédié à fournir des réponses d'experts à vos questions d'experts en hémostase.
Dans l’épisode d’aujourd’hui, notre experte Patricia Roger, nous parlera de la détermination des taux de facteurs dans le contexte d’une pathologie bien connue de tous, l’hémophilie !
Pour en savoir plus :
Littérature :
Alfonso Iorio,Jeffrey S. Stonebraker, Hervé Chambost, et al. Establishing the Prevalence and Prevalence at Birth of Hemophilia in Males: A Meta-analytic Approach Using National Registries. Ann Intern Med.2019;171:540-546. [Epub ahead of print 10 September 2019]. doi:10.7326/M19-12...2023-06-1910 min
Ask Stago (english version)S4E4 - Limit of detection (LoD) and limit of quantitation (LoQ): what are we talking about?Welcome to Ask Stago, The Podcast dedicated to provide expert answers to your expert questions in coagulation.
In today’s episode, our guest Florence Crépet will help us to understand what is behind the wording “limit of blank”, “limit of detection” and “limit of quantification”, and what it means for the clinical laboratory
Literature sources:
Armbruster DA, Pry T. Limit of blank, limit of detection and limit of quantitation. Clin Biochem Rev. 2008 Aug;29 Suppl 1(Suppl 1):S49-52.
CLSI. Evaluation of Detection Capability for Clinical Laboratory Measurement Procedures; Approved Guideline—Second Edition. CLSI document EP17-A2. Wayne, PA...2023-05-2314 min
🇫🇷 Ask Stago (version française)🇫🇷 S3E5 - Les tests viscoélastiquesBienvenue chez « Ask STAGO », le Podcast fournissant des réponses d'expert à vos questions d'expert en hémostase
Dans l'épisode d'aujourd'hui, Hubert Davenel, Spécialiste support clinique, nous explique les tests viscoélastiques et leur intérêt et usage.
Comme toujours n’hésitez pas à nous poser vos questions à ask@stago.com et nous serons heureux d’y répondre
Pour en savoir plus :
Littérature :
1. Hartert H. Blutgerinnungsstudien mit der Thrombelastographie, einem neuen Untersuchungsverfahren.Klin Wochenschr. 1948;26:577-583.
2. Sayce AC, Neal MD, Leeper CM. Viscoelastic monitoring in trauma resuscitation Transfusion...2023-05-1912 min
🇫🇷 Ask Stago (version française)🇫🇷 S3E4 - Les moteurs de règle, un moyen simple d’apporter l’expertise dans votre laboratoireBienvenue chez « Ask STAGO », le Podcast fournissant des réponses d'expert à vos questions d'expert en hémostase.
Dans l'épisode d'aujourd'hui, Manuela Stranieri, Service Manager de notre filiale Suisse, partagera avec nous l’efficacité constatée chez les clients ayant appliqués des algorithmes décisionnels automatisés.
Le contenu est de nature scientifique et technique. Il se veut un outil pédagogique pour les professionnels de laboratoire et les sujets abordés ne sont pas destinés à être des recommandations ou des commentaires sur la pratique clinique appropriée. 2023-04-2007 min
🇪🇸 Ask Stago (versión en español)🇪🇸 S1E10 - Cómo establecer un rango de referenciaBienvenido a Pregúntale a STAGO, el podcast que proporciona respuestas expertas a sus preguntas.
En el episodio de hoy, nuestra especialista de aplicaciones, Olivia Comella, nos explicará cómo establecer un rango de referencia en el laboratorio.
Fuentes bibliográficas:
• Henny J. Establecimiento y validación de intervalos de referencia en el laboratorio de biología médica. Ann Biol Clin 2011; 69(2) : 229-37 doi:10.1684/abc.2011.0537 • Gardiner, C, Coleman, R, de Maat, MPM, et al. International Council for Standardization in Haematology (ICSH) laboratory guidance for the evaluation of haemostasis analyser‐reagent test systems. Parte 1: Problemas esp...2023-04-1911 min
🇫🇷 Ask Stago (version française)🇫🇷 S3E3 - Égalité hommes-femmes au travail et en scienceBienvenue chez « Ask Stago », le Podcast fournissant des réponses d'expert à vos questions d'expert en hémostase.
Dans l’épisode d’aujourd’hui, qui coïncide avec la journée internationale de la femme (8 mars), nous nous concentrons sur l’égalité hommes-femmes dans la population active, et sur les raisons pour lesquelles atteindre cette égalité est bon pour les entreprises et la société en général. Nous rencontrons Eva Ohlsson Desormonts, directrice des ressources humaines du groupe Stago, et Amandine Serret, directrice marketing global, global business support et communication de Stago, ainsi que coach certifiée.
Comme toujours n...2023-03-0710 min
Ask Stago (english version)S4E3 - Women at work and Women in ScienceWelcome to Ask Stago, The Podcast dedicated to provide expert answers to your expert questions in coagulation.
In this episode, to coincide with International Womens Day (March 8th), we are focusing on Gender equality in the workforce, why this is good for business and good for society overall. We meet with Eva Ohlsson Desormonts, Group HR Director for Stago and Amandine Serret International Business Support and Communications Director for Stago as well as an Executive Coach.
Literature sources:
Women in the Workpace 2022, McKinsey & Company whitepaper
Challenges facing early career women in thrombosis and hemostasis—me...2023-03-0709 min
🇫🇷 Ask Stago (version française)🇫🇷 S3E2 - Qu’est-ce que la génération de thrombine ?Bienvenue chez « Ask STAGO », le Podcast fournissant des réponses d'expert à vos questions d'expert en hémostase.
Dans l'épisode d'aujourd'hui, Xavier Teuma, Manager Marketing réactifs et systèmes spécialisé, nous expliquera ce qu’est la génération de thrombine.
Pour en savoir plus :
Littérature :
Castoldi E, Rosing J. Thrombin generation tests. Thromb Res. 2011 Feb;127 Suppl 3:S21-5. doi: 10.1016/S0049-3848(11)70007-X
Baglin T. The measurement and application of thrombin generation. Br J Haematol. 2005 Sep;130(5):653-61. doi: 10.1111/j.1365-2141.2005.05612.x.
Hemker HC, Béguin S. Thrombin generation in plasma: its assessment...2023-02-1611 min
Ask Stago (english version)S4E2 - Women’s health series (part 2): Anti-phospholipid syndrome awarenessWelcome to Ask Stago, the Podcast dedicated to provide expert answers to your expert questions in coagulation.
In today’s episode, we are delighted to speak to April Matera. April experienced a stroke at the age of 39 and from there began her journey towards an anti-phospholipid syndrome diagnosis. Unfortunately it took 7 different visits to 7 different doctors to get her there. She tells us here about her APS road and how it has impacted her life and her dream to have a family.
Content is scientific and technical in nature. It is intended as an...2023-02-0714 min
🇫🇷 Ask Stago (version française)🇫🇷 S3E1 - Les clés pour implémenter un nouveau systèmeBienvenue chez « Ask STAGO », le Podcast fournissant des réponses d'expert à vos questions d'expert en hémostase.
Dans l'épisode d'aujourd'hui, Pauline Vasselon, US & Projects Registration Coordinator, nous partagera les points clés à vérifier lors de l’implémentation d’un nouveau système dans son laboratoire.
Pour en savoir plus :
Bibliographie utile:
ISO 15189 Medical laboratories — Requirements for quality and competence
ISO 22870:2010 Intelligent transport systems — Devices to aid reverse manoeuvres — Extended-range backing aid systems (ERBA)
CLSI Measurement Procedure Comparison and Bias Estimation Using Patient Samples, 3rd Edition, CLSI document EP09c, Wayne PA, 2018.
CLSI Evaluation...2023-01-1909 min
Ask Stago (english version)S4E1 - Women’s health series (part 1): Women’s health and coagulationWelcome to Ask Stago, the Podcast dedicated to provide expert answers to your expert questions in coagulation.
In this series of our new season we will be covering Womens’ health and looking at the broader implications of coagulation and then speaking to a Lupus patient advocate on the impact this disease has had for her personally.
To start off, in today episode, we are delighted to speak to our Clinical Development Director, Dr Francois Depasse about the broader connection between Womens’ Health and coagulation and then a more in depth look at APS.
Link...2023-01-0309 min
🇫🇷 Ask Stago (version française)🇫🇷 S2E12 - La thrombopénie induite par l’héparineBienvenue chez « Ask STAGO », le Podcast fournissant des réponses d'expert à vos questions d'expert en hémostase.
Dans l'épisode d'aujourd'hui, le Docteur Caroline Vayne, du CHU de Tours en France, nous donne un aperçu sur la thrombopénie induite par l'héparine.
Pour en savoir plus :
Littérature :
Gruel Y, Vayne C, Rollin J, Weber P, Faille D, Bauters A, Macchi L, Alhenc-Gelas M, Lebreton A, De Maistre E, Voisin S, Gouilleux-Gruart V, Perrin J, Tardy-Poncet B, Elalamy I, Lavenu-Bombled C, Mouton C, Biron C, Ternisien C, Nedelec-Gac F, Duchemin J, De Raucourt E, Goui...2022-12-1514 min
Ask Stago (english version)S3E12 - Fibrinolysis: the often missed key player of hemostasisWelcome to Ask Stago, The Podcast dedicated to provide expert answers to your expert questions in coagulation.
In today’s episode, our guest Professor Romaric Lacroix will explain us how fibrinolysis is important to the whole hemostasis process and how the sample fibrinolytic activity needs to be evaluated and sometimes monitored.
Link to previous podcasts:
S1E15 – Disseminated Intravascular Coagulation (DIC) and fibrin related markershttps://www.podcastics.com/podcast/episode/15-disseminated-intravascular-coagulation-dic-and-fibrin-related-markers-54016/
Literature sources:
Cointe S, Vallier L, Esnault P, Dacos M, Bonifay A, Macagno N, Harti Souab K, Chareyre C, Ju...2022-12-0609 min
🇫🇷 Ask Stago (version française)🇫🇷 S2E11 - Le Taux de prothrombine : quand test de routine ne veut pas dire simple !Bienvenue chez « Ask STAGO », le Podcast fournissant des réponses d'expert à vos questions d'expert en hémostase.
Dans l'épisode d'aujourd'hui, avec Pierre Bourgeat, Directeur opérationnel de l’amélioration continue et de l’expertise process, nous discuterons du taux de prothrombine et ses réactifs, avec un focus sur l’ISI et les types d’activateurs.
Pour en savoir plus :
Podcast :
Détermination temps témoin de prothrombine (MNPT) https://www.podcastics.com/podcast/episode/s1e4-comment-bien-determiner-son-temps-temoin-de-prothrombine-82377/
Webinar Ian Jennings sur stagowebinars.com
Littérature :
Lusher, J. Screening and diagnosis of...2022-11-1709 min
Ask Stago (english version)S3E11 - What is Factor parallelism for?Welcome to Ask Stago, the Podcast dedicated to provide expert answers to your expert questions in coagulation. In today’s episode, our guest Tom Childs will help us to understand the goal and clinical benefits of the Factor parallelism method.
Link to previous podcasts:
S1E11 – How to be more productive (part 1): implementation of a rules enginehttps://www.podcastics.com/podcast/episode/10-how-to-be-more-productive-part-1-implementation-of-a-rules-engine-37749/
S2E8 - World Hemophilia Dayhttps://www.podcastics.com/podcast/episode/s2e8-world-hemophilia-day-72341/
S2E4 - How to determine factor levels in hemophilia?https://www.pod...2022-11-0811 min
🇪🇸 Ask Stago (versión en español)🇪🇸 S1E9 - Ciberseguridad en el LaboratorioBienvenido a Pregúntale a STAGO, el podcast que proporciona respuestas expertas a sus preguntas.
En el episodio de hoy, nuestro referente de ciberseguridad Francesc Palomino nos explicará cómo la ciberseguridad está afectando las prácticas de laboratorio todos los días y por qué todos estamos hablando de ello.
Descargo de responsabilidad: El contenido es científico y técnico en su origen. Es una herramienta educacional para profesionales de laboratorio y los temas tratados no deben ser entendidos como una recomendación o como comentario de una práctica clínica apropiada.
No dud...2022-11-0205 min
🇫🇷 Ask Stago (version française)🇫🇷 S2E10 - Le dosage des AOD : comment, quand et pourquoi ?Bienvenue chez « Ask Stago», le Podcast fournissant des réponses d'expert à vos questions d'expert en hémostase.
Dans l'épisode d'aujourd'hui, notre invité expert est Jonathan Douxfils, président de QUALIBlood SA et professeur à l’université de Namur au département de pharmacie. Il détaillera les recommandations actuelles sur la mesure des anticoagulants directs oraux et les indications cliniques dans lesquelles ce dosage s’avère pertinent et utile.
Pour en savoir plus :
Bernier M, Lancrerot SL, Parassol N, Lavrut T, Viotti J, Rocher F, Drici MD. Therapeutic Drug Monitoring of Direct Oral Anticoagulants May Increase Their Benef...2022-10-2014 min
Ask Stago (english version)S3E10 - Pediatric hemostasis: are children “small adults”?Welcome to Ask Stago, The Podcast dedicated to provide expert answers to your expert questions in coagulation.
In today’s episode, our guest Gabrielle Pearl will explain us the particularities of thrombosis and hemostasis in pediatric population, and how to manage pediatric patient samples in the clinical laboratory.
Link to previous podcasts:
S2E5 - How to collect and prepare the coagulation samples properly?
https://www.podcastics.com/podcast/episode/s2e5-how-to-collect-and-prepare-the-coagulation-samples-properly-67393/
S2E3 - How to establish and control the reference range of my assay?
https://www.podcastics.com/po...2022-10-0409 min
🇪🇸 Ask Stago (versión en español)🇪🇸 S1E8 - EQA - eiQCBienvenido a Pregúntale a STAGO, el podcast que proporciona respuestas expertas a sus preguntas.
En el episodio de hoy, gracias a Daniel Corbacho, coordinador del servicio de atención al cliente y control de calidad, le ayudaremos a diferenciar y comprender el objetivo de los programas de control de calidad interno externalizado (eIQC) y evaluación del control de calidad externo (EQA).
Fuentes bibliográficas:
· Alfonso Iorio, Jeffrey S. Stonebraker, Hervé Chambost, et al. Establecimiento de la prevalencia y prevalencia al nacer de la hemofilia en hombres: un enfoque metaanalítico utilizando registros naci...2022-10-0307 min
🇫🇷 Ask Stago (version française)🇫🇷 S2E9 - Le B.A.BA du prélèvement sanguin pour l’hémostaseBienvenue chez « Ask STAGO », le Podcast fournissant des réponses d'expert à vos questions d'expert en hémostase.
Dans l'épisode d'aujourd'hui, Marie-Louise Alonso, longtemps coordinatrice de l’Hopital Maisonneuve-Rosemont de Montréal partagera avec nous les conseils utiles pour réaliser un prélèvement sanguin pour la paillasse d’Hémostase dans les meilleures conditions.
Pour en savoir plus :
Stability of coagulation proteins in frozen plasma. B. Woodhams, O. Girardot, MJ Blanco and Y.Gourmelin, Blood coagulation and fibrinolysis 2001, 12:229-236
Effects of storage time and temperature on coagulation tests and factors in fresh plasma Limin Feng, Ying...2022-09-2215 min
Ask Stago (english version)S3E9 - The importance of Fibrinogen.Welcome to Ask Stago, the podcast dedicated to provide expert answers to your expert questions in hemostasis.
In today episode, our expert Lydie Nicoud, R&D reagent manager, will talk with us about the test of fibrinogen.
As usual, don’t forget to send any question you may have to ask@stago.com, we will be glad to answer to it.
Literature sources:
Miesbach W, Schenk J, Alesci S, Lindhoff-Last E, Comparison of the fibrinogen Clauss assay and the fibrinogen PT derived method in patients with dysfibrinogenemia .Thromb Res. 2010; 126(6): e428-33
Karapetian H...2022-09-0611 min
🇫🇷 Ask Stago (version française)🇫🇷 S2E8 - Le risque thrombotique associé à la prise de traitements hormonauxBienvenue chez « Ask STAGO », le Podcast fournissant des réponses d'expert à vos questions d'expert en hémostase.
Dans l'épisode d'aujourd'hui, notre invitée Laure Morimont, cheffe de projet et doctorante chez QUALIBlood SA, reviendra avec nous sur les connaissances actuelles autour du risque thrombotique associé aux traitements hormonaux et comment ce risque peut être évalué.
Pour en savoir plus :
Littérature :
de Bastos M, Stegeman BH, Rosendaal FR, Van Hylckama Vlieg A, Helmerhorst FM, Stijnen T, Dekkers OM. Combined oral contraceptives: venous thrombosis. Cochrane Database of Systematic Reviews 2014, Issue 3. Art. No.: CD010813. DOI: 10.1002/1...2022-09-0208 min
🇪🇸 Ask Stago (versión en español)🇪🇸 S1E7-Monitorizar HNFBienvenido a Pregúntale a Stago, el podcast para profesionales del laboratorio de hemostasia.
En el episodio de hoy, con nuestra experta Eliazar Camino, especialista en aplicaciones, comenzarán a cuestionarse cómo podemos monitorizar la heparina no fraccionada (HNF o UHF).
Descargo de responsabilidad: El contenido es científico y técnico en su origen. Es una herramienta educacional para profesionales de laboratorio y los temas tratados no deben ser entendidos como una recomendación o como comentario de una práctica clínica apropiada.
No duden en enviarnos cualquier pregunta que puedan te...2022-09-0108 min
Ask Stago (english version)S3E8 - Venoms and coagulation: when evolution reveals useful for drug and assay development.Welcome to Ask Stago, The Podcast dedicated to provide expert answers to your expert questions in coagulation.
In today’s episode, our guest Dr Bryan G Fry, aka Venom Doc, will make us enter his world and understand how venom interact with coagulation and how they can prove useful for assay or drug design & development
Literature sources:
Fry BG, Roelants K, Champagne DE, Scheib H, Tyndall JD, King GF, Nevalainen TJ, Norman JA, Lewis RJ, Norton RS, Renjifo C, de la Vega RC. The toxinogenomic multiverse: convergent recruitment of pr...2022-08-0211 min
🇫🇷 Ask Stago (version française)🇫🇷 S2E7 - Le boom digital des laboratoires d’analyses médicalesBienvenue chez « Ask Stago», le Podcast fournissant des réponses d'experts à vos questions d'experts en hémostase.
Dans l'épisode d'aujourd'hui, c’est Cécile Hourquet, Responsable de gamme eSolutions et services, et habituellement animatrice qui prendra la place d’invité pour parler de la transformation profonde du quotidien des laboratoires d’analyses médicales grâce à la digitalisation.
Pour en savoir plus :
Podcast associé : Episode Ask Stago 🇫🇷 S1E3 - La cybersécurité pour les laboratoires médicaux
🎧 Apple Podcasts : https://lnkd.in/dTpjjXz
Google Podcasts: https://lnkd.in/d7NfJ5X
Spotify : https://lnkd.in/dq_FYXr ...2022-07-2810 min
🇫🇷 Ask Stago (version française)🇫🇷 S2E6 - Quand et comment réaliser un bilan de thrombophilie ?Bienvenue chez « Ask Stago», le Podcast fournissant des réponses d'experts à vos questions d'experts en hémostase.
Dans l'épisode d'aujourd'hui, avec David Courtois, Responsable de gamme au marketing global, nous aborderons quand et comment un bilan de thombophilie peut-être réalisé de manière pragmatique et efficace pour le laboratoire
Pour en savoir plus :
Podcast associé : Episode Ask Stago 🇫🇷 S2E3 Le bilan biologique pour le diagnostic du lupus anticoagulant
🎧 Apple Podcasts : https://lnkd.in/dTpjjXz
Google Podcasts: https://lnkd.in/d7NfJ5X
Spotify : https://lnkd.in/dq_FYXr
Deezer : https...2022-07-0815 min
Ask Stago (english version)S3E7 - Hemostasis results interpretation along pregnancy.Welcome to Ask Stago, the Podcast dedicated to provide expert answers to your expert questions in coagulation.
In today’s episode, our guest François Depasse will help us to understand the hemostasis results obtained along pregnancy, what are the related difficulties for the lab and
Link to previous podcasts:
S1E15 Disseminated Intravascular Coagulation (DIC) and fibrin related markers:https://www.podcastics.com/podcast/episode/15-disseminated-intravascular-coagulation-dic-and-fibrin-related-markers-54016/
S2E1 Whole Blood Viscoelastic Testing (VET)https://www.podcastics.com/podcast/episode/s2e1-whole-blood-viscoelastic-testing-vet-55204
Literature sources:
Szecsi PB, Jørgen...2022-07-0516 min
🇪🇸 Ask Stago (versión en español)🇪🇸 S1E6 - Reglas Expertas - Productividad en el LaboratorioBienvenido a Pregúntale a Stago, el podcast para profesionales del laboratorio de hemostasia.
En el episodio de hoy, con nuestra experta Esther Abella, especialista en aplicaciones, comenzarán a cuestionarse cómo podemos ayudar al laboratorio a ser más productivo con algunas soluciones de middleware: motores de reglas.
Descargo de responsabilidad: El contenido es científico y técnico en su origen. Es una herramienta educacional para profesionales de laboratorio y los temas tratados no deben ser entendidos como una recomendación o como comentario de una práctica clínica apropiada.
No duden...2022-07-0107 min
🇫🇷 Ask Stago (version française)🇫🇷 S2E5 - La valeur de l’information diagnostiqueBienvenue chez « Ask Stago», le Podcast fournissant des réponses d'experts à vos questions d'experts en hémostase.
Dans l'épisode d'aujourd'hui, avec Audrey Carlo, responsable marketing scientifique, nous aborderons l’évaluation des technologies de santé, l’approche médico-économique et la valeur de l’information diagnostique.
Pour en savoir plus :
Littérature :
Wurcel V, Cicchetti A, Garrison L, Kip MMA, Koffijberg H, Kolbe A, Leeflang MMG, Merlin T, Mestre-Ferrandiz J, Oortwijn W, Oosterwijk C, Tunis S, Zamora B. The Value of Diagnostic Information in Personalised Healthcare: A Comprehensive Concept to Facilitate Bringing This Technology in...2022-06-1709 min
Ask Stago (english version)S3E6 - IVDR: what is at stake for IVD manufacturers and for the laboratories?Welcome to Ask Stago, The Podcast dedicated to provide expert answers to your expert questions in coagulation.
In today’s episode, our guest Sophie Réhault will give us explanations on what is the new EU IVD regulation and what it implies both for IVD manufacturers and for the clinical laboratories.
Link to previous podcasts:
S2E18 – Practical check list of the implementation of an instrument in your lab:https://www.podcastics.com/podcast/episode/s2e18-practical-check-list-of-the-implementation-of-an-instrument-in-your-lab-103649/
S3E4 – All you need to know about instrument validation: https://www.podcastics.com/podcast...2022-06-0711 min
🇫🇷 Ask Stago (version française)🇫🇷 S2E4 - Booster votre productivité – La workcellBienvenue chez « Ask Stago», le Podcast fournissant des réponses d'experts à vos questions d'experts en hémostase.
Dans l'épisode d'aujourd'hui, Marie Valentin, Chef de produit Automation et Middleware France, nous expliquera comment une Workcell peut aider à optimiser la productivité de votre laboratoire.
Liens utiles :
Episode Ask Stago 🇫🇷 S1E8 Le Lean six sigma, un outils pour améliorer votre productivité
🎧 Apple Podcasts : https://lnkd.in/dTpjjXz
Google Podcasts: https://lnkd.in/d7NfJ5X
Spotify : https://lnkd.in/dq_FYXr
Deezer : https://lnkd.in/d-nu9d3
YouTube : https://youtu.be/e9OjJw9TAHw
Le contenu est...2022-05-1910 min
Ask Stago (english version)S3E5 - Should we handle veterinary citrated blood samples like human ones?Welcome to Ask Stago, The Podcast dedicated to provide expert answers to your expert questions in coagulation.
In today’s episode, our guest Daniel Pilbeam, from the Clinical Pathology Laboratory at UVet in Melbourne will help us understand the common points and differences between veterinary and human hemostasis, and what should be critically assessed.
Previous episodes in relation to the topic:
AskStago episode #9 (season 1): How to manage HIL samples in the coagulation laboratory?
Literature sources:
John W. Harvey, Veterinary Hematology, Chapter 7 - Evaluation of Hemostasis: Coagulation and Platelet Disor...2022-05-0309 min
Ask Stago (english version)S3E4 - All you need to know about instrument validation.Welcome to Ask Stago, the podcast dedicated to provide expert answers to your expert questions in coagulation.
In today’s episode, our guest Kaitlyn Pelc will explain further the different steps to validate an instrument at the installation.
Previous episodes in relation to the topic:
S2E18 – Practical check list of the implementation of an instrument in your lab: https://www.podcastics.com/podcast/episode/s2e18-practical-check-list-of-the-implementation-of-an-instrument-in-your-lab-103649/
S2E3 – How to establish and control the reference range of my assay: https://www.podcastics.com/podcast/episode/s2e3-how-to-establish-and-control-the-reference-range-of-my-assay-60155/
S2E2 - How to cali...2022-04-0510 min
🇫🇷 Ask Stago (version française)🇫🇷 S2E3 - Le bilan biologique pour le diagnostic du lupus anticoagulantBienvenue chez « Ask Stago», le Podcast fournissant des réponses d'experts à vos questions d'experts en hémostase.
Dans l'épisode d'aujourd'hui avec Claire Martin, responsable d’équipe et chef de projet en recherche et développement, nous aborderons l’arbre diagnostic pour le lupus anticoagulant.
Pour en savoir plus :
Littérature :
Miyakis S, Lockshin MD, Atsumi T, Branch DW, Brey RL, Cervera R, Derksen RH, De Groot PG, Koike T, Meroni PL, Reber G, Shoenfeld Y, Tincani A, Vlachoyiannopoulos PG, Krilis SA. International consensus statement on an update of the classification criteria for definite antiphosphol...2022-03-1709 min
Ask Stago (english version)S3E3 - Demystifying platelet aggregometryWelcome to Ask Stago, the podcast dedicated to provide expert answers to your expert questions in hemostasis.
In today’s episode, our guest David Courtois will explain further what is platelet aggregometry, how to measure it and in which indications it is useful.
Literature sources:
Born GVR. Aggregation of blood platelets by adenosine disphosphate and its reversal. Nature 1962; 194: 927 – 929.
O’Brien JR. Platelet aggregation. II. Some results from a new method of study. J Clin Pathol 1962; 15: 452-458.
Caen JP, Michel H. Platelet shape change and aggregation. Nature 1972; 240 (5377): 148-149.
Holmsen H. Platelet metabolism and activat...2022-03-0110 min
🇫🇷 Ask Stago (version française)🇫🇷 S2E2 - Comment déterminer son intervalle de référenceBienvenue chez « Ask Stago», le Podcast fournissant des réponses d'experts à vos questions d'experts en hémostase.
Dans l'épisode d'aujourd'hui, Jérôme Pinto, Responsable Equipe Application International, nous explique comment établir et valider les valeurs références des méthodologies d’hémostase.
Pour en savoir plus :
Henny J. Établissement et validation des intervalles de référence au laboratoire de biologie médicale. Ann Biol Clin 2011 ; 69(2) : 229-37 doi:10.1684/abc.2011.0537
Gardiner, C, Coleman, R, de Maat, MPM, et al. International Council for Standardization in Haematology (ICSH) laboratory guidance for the evaluation of haemostasis analyser‐reagent te...2022-02-1711 min
Ask Stago (english version)S3E2 - EQA, a valuable tool for laboratories.Welcome to Ask Stago, the podcast dedicated to provide expert answers to your expert questions in hemostasis.
In today episode, our expert Charlotte Parent, Marketing product manager, will talk with us about the EQA. A valuable tool to ensure the quality of laboratory results.
As usual, don’t forget to send any question you may have to ask@stago.com, we will be glad to answer to it.
Literature sources:
Ask Stago season 1 episode 3: eIQC and EQA: benefits and differences https://www.podcastics.com/podcast/episode/3-eiqc-and-eqa-benefits-and-differences-35848/
ISO 15189:2012, Medical laboratories — Requir...2022-02-0106 min
🇫🇷 Ask Stago (version française)🇫🇷 S2E1- Comment bien réaliser ses calibrations de dosagesBienvenue chez « Ask Stago», le Podcast fournissant des réponses d'experts à vos questions d'experts en hémostase.
Dans l'épisode d'aujourd'hui, Hinede ABDALLAOUI, Responsable du centre de support client, nous donne les clés pour réaliser des calibrations robustes avec vos réactifs d’hémostase.
Pour en savoir plus :
Episode Ask Stago 🇫🇷 S1E4 - Comment bien déterminer son temps témoin de Prothrombin
🎧 Apple Podcasts : https://lnkd.in/dTpjjXz
Google Podcasts: https://lnkd.in/d7NfJ5X
Spotify : https://lnkd.in/dq_FYXr
Deezer : https://lnkd.in/d-nu9d3
YouTube : https://lnkd.in/d...2022-01-2007 min
Ask Stago (english version)S3E1 - Heparin induced thrombocytopenia: making it clear.Welcome to Ask Stago, the podcast dedicated to provide expert answers to your expert questions in hemostasis.
In today episode, our expert guest, Dr Caroline Vayne from Tours University Hospital in France, gives us an overview on heparin induced thrombocytopenia.
As usual, don’t forget to send any question you may have to ask@stago.com, we will be glad to answer to it.
Learn more:
Gruel Y, Vayne C, Rollin J, Weber P, Faille D, Bauters A, Macchi L, Alhenc-Gelas M, Lebreton A, De Maistre E, Voisin S, Gouilleux-Gruart V...2022-01-0412 min
🇫🇷 Ask Stago (version française)🇫🇷 S1E9 - La CIVD et les biomarqueurs fibrino-dépendantsBienvenue chez « Ask Stago», le Podcast fournissant des réponses d'experts à vos questions d'experts en hémostase.
Dans l'épisode d'aujourd'hui, avec François Hamon notre directeur Business Développement, nous discuterons de l’utilité de différents biomarqueurs fibrino-dépendants dans le diagnostic de coagulation intravasculaire disséminée.
Pour en savoir plus :
Baglin T. Disseminated intravascular coagulation: diagnosis and treatment. BMJ 1996; 312: 683-7
Iba T, Di Nisio M, Thachil J, Wada H, Asakura H, Sato K, Kitamura N, Saitoh D. Revision of the Japanese Association for Acute Medicine (JAAM) disseminated intravascular coagulation (DIC) diagnostic criteria using antithrombin activity. Crit Care. 201...2021-12-1608 min
Ask Stago (english version)S2E19 - HTA and value of diagnostic informationWelcome to Ask Stago, The Podcast dedicated to provide expert answers to your expert questions in coagulation.
In today’s episode, our co-host Audrey Carlo will share her understanding on what is HTA and why Value of Diagnostic Information should be further recognized.
Literature sources:
Wurcel V, Cicchetti A, Garrison L, Kip MMA, Koffijberg H, Kolbe A, Leeflang MMG, Merlin T, Mestre-Ferrandiz J, Oortwijn W, Oosterwijk C, Tunis S, Zamora B. The Value of Diagnostic Information in Personalised Healthcare: A Comprehensive Concept to Facilitate Bringing This Technology into Healthcare Systems. Public Health Genomics. 2019;22(1-2):8-1...2021-12-0709 min
🇫🇷 Ask Stago (version française)🇫🇷 S1E8 - Le Lean six sigma, un outils pour améliorer votre productivitéBienvenue chez « Ask Stago», le Podcast fournissant des réponses d'experts à vos questions d'experts en hémostase.
Dans l'épisode d'aujourd'hui, Andres Ramirez, Manager du pôle Marketing Automation, nous parle d’une technique très utilisée pour améliorer et simplifier son quotidien : Le lean six sigma .
Le contenu est de nature scientifique et technique. Il se veut un outil pédagogique pour les professionnels de laboratoire et les sujets abordés ne sont pas destinés à être des recommandations ou des commentaires sur la pratique clinique appropriée. 2021-11-1811 min
Ask Stago (english version)S2E18 - Practical check list of the implementation of an instrument in your labWelcome to Ask Stago, The Podcast dedicated to provide expert answers to your expert questions in coagulation.
In today’s episode, our expert Pauline Vasselon, US & Projects Registration Coordinator within Stago Market Access team, will provide us the key steps to implement a new instrument in your laboratory.
Literature sources:
ISO 15189 Medical laboratories — Requirements for quality and competence
ISO 22870:2010 Intelligent transport systems — Devices to aid reverse manoeuvres — Extended-range backing aid systems (ERBA)
CLSI Measurement Procedure Comparison and Bias Estimation Using Patient Samples, 3rd Edition, CLSI document EP09c, Wayne PA, 2018.
CLSI Evaluation of Precision of Quantitative Measuremen...2021-11-0209 min
🇫🇷 Ask Stago (version française)🇫🇷 S1E7- Suivi des HNF : TCA ou Anti-Xa ?Bienvenue chez « Ask Stago», le Podcast fournissant des réponses d'experts à vos questions d'experts en hémostase.
Dans l'épisode d'aujourd'hui, avec François Depasse, notre directeur du développement clinique, nous discuterons du suivi des héparines non-fractionnées (HNF) et de l'outil approprié pour le faire : TCA ou activité anti-Xa ?
Pour en savoir plus :
Johnson EA, Mullboy B. The molecular weight range of commercial heparin preparations. Carbohydr Res 1976; 51: 119-127
Hirsh J, Raschke R, Heparin and Low-molecular-weight heparin : the Seventh ACCP Conference on Antithrombotic and thrombolytic therapy. CHEST 2004; 126 (suppl 3): 188S-203S.
Basu D, Gallus A, Hirsh J, Cade J. A prospective s...2021-10-2108 min
🇪🇸 Ask Stago (versión en español)🇪🇸 S1E5 - El trabajo de diagnóstico de ALEsta semana en, Ask Stago, el podcast semanal dedicado a ofrecer respuestas de expertos a sus preguntas de expertos en coagulación, hablaremos con nuestra experta Alejandra Chang, especialista de producto, sobre cómo realizar con precisión un diagnóstico de LA en el laboratorio.
Fuentes:
· Miyakis S, Lockshin MD, Atsumi T, Branch DW, Brey RL, Cervera R, Derksen RH, De Groot PG, Koike T, Meroni PL, Reber G, Shoenfeld Y, Tincani A, Vlachoyiannopoulos PG, Krilis SA. International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS). J Thromb Haemost 2006...2021-10-1910 min
Ask Stago (english version)S2E17 - World Thrombosis DayWelcome to Ask Stago, the podcast dedicated to provide expert answers to your expert questions in hemostasis.
In today episode, our expert guest, Dr Stephan Moll, will give a hint of his webinar entitled “The Patient with Venous Thrombosis – Practical Points for the Laboratorian and the Clinician”.
As usual, don’t forget to send any question you may have to ask@stago.com, we will be glad to answer to it.
Learn more:
Detailed DVT/PE brochure for patients: Moll S, Waldron B. DVT and PE: Information for newly diagnosed patients. Clot Connect...2021-10-0511 min
🇪🇸 Ask Stago (versión en español)🇪🇸 S1E4 - Cómo manejar muestras HILEl objetivo es proporcionar información acerca de cómo manejar las interferencias HIL en el laboratorio de coagulación
Fuente:
· Lippi G et al., Interference of blood cell lysis on routine coagulation testing. Arch Pathol Lab Med. 2006;130(2):181-4
· Woolley A et al., Effects of haemolysis, icterus and lipaemia on coagulation tests as performed on Stago STA-Compact-Max analyser. Int J Lab Hematol. 2016; 38(4): 375-88
· Plebani M, Quality Indicators to Detect Pre-Analytical Errors in Laboratory Testing, Clin Biochem Rev 2012; 3: 85-88.
· Salvagno GL et al, Prevalence and type of pre-analytical problems for inpatients samples in coagulation...2021-09-1608 min
🇫🇷 Ask Stago (version française)🇫🇷 S1E6 - Comment gérer les échantillons HIL au laboratoire d’hémostase ?Bienvenue chez « Ask Stago», le Podcast fournissant des réponses d'experts à vos questions d'experts en hémostase.
Dans l'épisode d'aujourd'hui, avec notre expert Frédéric Brutto, responsable de gamme, Cécile Hourquet et Audrey Carlo s'interrogeront sur les interférences HIL et comment le laboratoire de coagulation peut les gérer.
Pour en savoir plus :
Lippi G et al., Interference of blood cell lysis on routine coagulation testing. Arch Pathol Lab Med. 2006;130(2):181-4
Woolley A et al., Effects of haemolysis, icterus and lipaemia on coagulation tests as performed on Stago STA-Compact-Max analyser. Int J Lab Hematol. 2016; 38(4): 375-8...2021-09-1607 min
Ask Stago (english version)S2E16 - DOAC measurement: how and what for?Welcome to Ask Stago, the podcast dedicated to provide expert answers to your expert questions in hemostasis.
In today episode, our expert guest, Jonathan Douxfils, CEO at QUALIblood SA and Professor at the University of Namur / Department of Pharmacy, will detail with us the current recommendation on how to measure direct oral anticoagulants and in which clinical situation this information is relevant and useful..
As usual, don’t forget to send any question you may have to ask@stago.com, we will be glad to answer to it.
Learn more - Literature sources:
Ber...2021-09-0711 min
Ask Stago (english version)S2E15 - Quality controls: how to establish the QC ranges?Welcome to Ask Stago, the podcast dedicated to provide expert answers to your expert questions in haemostasis.
In today episode, our expert Arnaud Rouvière, Global process – Service manager, will provide us all the current recommendations to establish your Quality control ranges.
As usual, don’t forget to send any question you may have to ask@stago.com, we will be glad to answer to it.
Learn more - Previous mentioned podcast :
Previous episode with Arnaud Rouvière : S1E7 How to determine the mean normal prothrombin time
Learn more about the externaliz...2021-08-0308 min
🇪🇸 Ask Stago (versión en español)🇪🇸 S1E3 - Cómo determinar el MNPT para la INREl objetivo es proporcionar nuestros mejores consejos para calcular el Tiempo de Protrombina Normal Medio para la prueba de INR.
Fuente:
WHO technical report series ; no. 979, 2013
Descargo de responsabilidad: El contenido es científico y técnico en su origen. Es una herramienta educacional para profesionales de laboratorio y los temas tratados no deben ser entendidos como una recomendación o como comentario de una práctica clínica apropiada.2021-07-1606 min
Ask Stago (english version)S2E14 - Oral contraception and thrombotic riskWelcome to Ask Stago, the podcast dedicated to provide expert answers to your expert questions in hemostasis.
In today episode, our expert guest, Laure Morimont, Project leader at QUALIblood SA, will detail with us the current knowledge on thrombotic risk under hormonal therapy and how this can be assessed.
As usual, don’t forget to send any question you may have to ask@stago.com, we will be glad to answer to it.
Learn more ⬇️
Literature sources:
de Bastos M, Stegeman BH, Rosendaal FR, Van Hylckama Vlieg A, Helmerhorst FM, Stijnen T, Dekkers OM. Combined oral contracep...2021-07-0608 min
🇪🇸 Ask Stago (versión en español)🇪🇸 S1E2 - Anomalías en la coagulación en pacientes COVID-19El objetivo es proporcionar información acerca de cómo la infección con COVID-19 afecta la coagulación y cómo estas anomalías en la coagulación deberían ser monitoreadas.
Fuentes:
Tang N, Li D, Wang X, Sun Z. Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia. J Thromb Haemost 2020;18:844–7.
Moores LK, Tritschler T, Brosnahan S et al, Prevention, Diagnosis, and Treatment of VTE in Patients With Coronavirus Disease 2019, CHEST Guideline and Expert Panel Report, CHEST 2020; 158(3): 1143-63
Descargo de responsabilidad: El contenido es científico y técnico en s...2021-06-2208 min
Ask Stago (english version)S2E13 - Why is the lab turning digital?Welcome to Ask Stago, the podcast dedicated to provide expert answers to your expert questions in haemostasis.
In today episode, our co-host Cécile Hourquet, Product Line Manager for eSolutions and services, will come to talk about the digitalization of the laboratories.
As usual, don’t forget to send any question you may have to ask@stago.com, we will be glad to answer to it.
Content is scientific and technical in nature. It is intended as an educational tool for laboratory professionals and topics discussed are not intended as recommendations or as commentary on...2021-06-2207 min
Ask Stago (english version)S2E12 - Demystifying measurement uncertaintyWelcome to Ask Stago, the podcast dedicated to provide expert answers to your expert questions in coagulation.
In today episode, Stephen MacDonald, Principal Clinical Scientist from Cambridge University Hospital, will demystify the process of Measurement Uncertainty determination.
As usual, don’t forget to send any question you may have to ask@stago.com, we will be glad to answer to it.
To learn more:
Go on the websites 👉 https://pathologyuncertainty.com/
👉 https://www.pathologymu.com/
👉 https://pathologymu.teachable.com/
Follow there Twitter https://twitter.com/pathologyMU?
Literature:
ISO/TS 20914: 2019 Medical laboratories –...2021-06-0809 min
Ask Stago (english version)S2E11 - What is thrombin generation?Welcome to Ask Stago, the podcast dedicated to provide expert answers to your expert questions in haemostasis.
In today episode, our expert Marisa Ninivaggi, research project leader at Synapse research institute, will explain us what is thrombin generation.
As usual, don’t forget to send any question you may have to Ask@stago.com, we will be glad to answer to it.
Learn more 👇
Literature sources:
Castoldi E, Rosing J. Thrombin generation tests. Thromb Res. 2011 Feb;127 Suppl 3:S21-5. doi: 10.1016/S0049-3848(11)70007-X
Baglin T. The measurement and application of thrombin generation. Br J Haemat...2021-05-2509 min
🇪🇸 Ask Stago (versión en español)🇪🇸 S1E1 - Como manejar muestras de COVIDEl objetivo es proporcionar una guía acerca de las mejores prácticas para el manejo de muestras de pacientes con COVID-19 y responder preguntas frecuentes sobre el manejo general como por ejemplo la preparación de muestras e interferencias HIL. Inducidas por la infección de COVID 19.
Fuentes: Wang W, Xu Y, Gao R, et al. Detection of SARS-CoV-2 in Different Types of Clinical Specimens. JAMA. 2020;323(18):1843–1844. doi:10.1001/jama.2020.3786
Descargo de responsabilidad: El contenido es científico y técnico en su origen. Es una herramienta educacional para profesionales de laboratorio y los temas tratados no deben...2021-05-1407 min
Ask Stago (english version)S2E10 - How to manage lot conversion in your daily lab management?Welcome to Ask Stago, the podcast dedicated to provide expert answers to your expert questions in haemostasis.
In today episode, our expert Rachael Lamma, a member of our US technical support specialist team, will explain how to handle lot conversion in the daily laboratory organization.
As usual, don’t forget to send any question you may have to Ask@stago.com, we will be glad to answer to it.
Learn more 👇
Literature sources:
College of American Pathologists. All Common Checklist. Northfield, IL: College of American Pathologists; 2020
CLSI. User Evaluation of Between-Reagent Lot Variation; Approved Gu...2021-05-1109 min
🇫🇷 Ask Stago (version française)🇫🇷 S1E1 - Différencier le contrôle interne de qualité externalisé et l’Evaluation Externe de la QualitéBienvenue chez « Ask Stago », le Podcast fournissant des réponses d'experts à vos questions d'experts en hémostase.
Dans l'épisode d'aujourd'hui, Minh-Lan Nguyen, responsable de gamme pour MyExpertQC, nous aide à différencier et à comprendre l'objectif des programmes de contrôle interne de qualité externalisé (CIQe) et l’évaluation externe de la qualité externe (EEQ).
Pour en savoir plus :
SPECTRA BIOLOGIE n° 229 • Juin - Juillet 2017 http://www.spectrabiologie.fr/wp-content/uploads/2018/02/PUBLI-STAGO-SB229_V5.pdf
SH-GTA-14
Norme ISO 15189
Le contenu est de nature scientifique et technique. Il se veut un outil pédagogique pour les professionnels de laboratoire et les sujets...2021-04-2706 min
Ask Stago (english version)S2E9 - When and how to perform thrombophilia testingWelcome to Ask Stago, the Podcast dedicated to provide expert answers to your expert questions in coagulation.
In today’s episode, our expert our expert François Depasse, Clinical development Director, will help us to clarify when thrombophilia testing is appropriate and how to perform it according to international standards.
As usual, don’t forget to send any question you may have to ask@stago.com we will be glad to answer to it.
Literature sources:
https://www.cochranelibrary.com/advanced-search/mesh;jsessionid=DED8CB403679070FD38E81E38E5A7ECA accessed March 17, 2021
Montagn...2021-04-2712 min
Ask Stago (english version)S2E8 - World Hemophilia DayWelcome to Ask Stago, the Podcast dedicated to provide expert answers to your expert questions in coagulation.
In today’s episode, our expert Paul, in honor of the upcoming World Hemophilia Day, taking place April 17, will return to our podcast series to cover clinical laboratory testing approaches for patients with inherited or acquired haemophilia.
Literature sources:
Iorio A, Stonebraker JS, Chambost H, Makris M, Coffin D, Herr C, et al.; Data and Demographics Committee of the World Federation of Hemophilia. Establishing the Prevalence and Prevalence at Birth of Hemophilia in Males: A Meta-analytic Approach Using National Registries...2021-04-1314 min
Ask Stago (english version)S2E7 - APTT, not a one-for-all-purposes reagentWelcome to Ask Stago, the Podcast dedicated to provide expert answers to your expert questions in coagulation. In today episode, our expert Thomas, is covering with us the usages of APTT testing.
Literature sources:
Toulon, P., Eloit, Y., Smahi, M., Sigaud, C., Jambou, D., Fischer, F. and Appert‐Flory, A. (2016), In vitro sensitivity of different activated partial thromboplastin time reagents to mild clotting factor deficiencies. Int. Jnl. Lab. Hem., 38: 389-396. https://doi.org/10.1111/ijlh.12499
CLSI One-stage Prothrombin Time (PT) test and Activated Partial Thromboplastin Time (APTT) test; Approved guideline - second edition. CLSI document H47-A2 Wayne, P...2021-03-3010 min
Ask Stago (english version)S2E6 - Prothrombin Time routine does not mean "simple"Welcome to Ask Stago, The Podcast dedicated to provide expert answers to your expert questions in hemostasis.
In today episode, our expert Pierre Bourgeat, will discuss about the Prothrombin time reagent characteristics with a specific focus on the ISI and the type of activators.
As usual, don’t forget to send any question you may have to Ask@stago.com, we will be glad to answer to it.
To learn more:
Listen to our podcast about MNPT determination: #7 How to determine the mean normal prothrombin time
View the Webinar of Ian Jenning on stagowe...2021-03-1609 min
Ask Stago (english version)S2E5 - How to collect and prepare the coagulation samples properly?Welcome to Ask Stago, The Podcast dedicated to provide expert answers to your expert questions in coagulation. In today episode, our expert Vicki, will give you all her tips to collect and prepare you sample in the best way. From sample, material or storage be sure to provide valid sample to your lab. A podcast to share with your colleague, nurses or any person in charge of the preparation of the sample in your facility.
As usual, don’t forget to send any question you may have to Ask@stago.com, we will be glad to answer to it.
2021-03-0210 min
Ask Stago (english version)S2E4 - How to determine factor levels in hemophilia?Welcome to Ask Stago, The Podcast dedicated to provide expert answers to your expert questions in coagulation. In today episode, our expert Alex, will discuss with us how to determine factor levels in hemophilia patients.
Literature sources:
Alfonso Iorio,Jeffrey S. Stonebraker, Hervé Chambost, et al. Establishing the Prevalence and Prevalence at Birth of Hemophilia in Males: A Meta-analytic Approach Using National Registries. Ann Intern Med.2019;171:540-546. [Epub ahead of print 10 September 2019]. doi:10.7326/M19-1208
Blanchette, VS, Key, NS, Ljung, LR, Manco‐Johnson, MJ, van Den Berg, HM, Srivastava, A, for the Subcommittee on Factor VIII, Factor IX...2021-02-1608 min
Ask Stago (english version)S2E3 - How to establish and control the reference range of my assay?Welcome to Ask Stago, The Podcast dedicated to provide expert answers to your expert questions in coagulation. In today episode, our expert Tara Simpson, will cover with us how to establish and control an assay reference range.
Literature sources:
Henny J. Établissement et validation des intervalles de référence au laboratoire de biologie médicale. Ann Biol Clin 2011 ; 69(2) : 229-37 doi:10.1684/abc.2011.0537
Gardiner, C, Coleman, R, de Maat, MPM, et al. International Council for Standardization in Haematology (ICSH) laboratory guidance for the evaluation of haemostasis analyser‐reagent test systems. Part 1: Instrument‐specific issues and commonly used coagula...2021-02-0209 min
Ask Stago (english version)S2E2 - How to calibrate your reagent as a pro.Welcome to Ask Stago, The Podcast dedicated to provide expert answers to your expert questions in coagulation.
In today episode, our expert Draga, will give you all her tips to have the perfect calibration.
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Content is scientific and technical in nature. It is intended as an educational tool for laboratory professionals and topics discussed are not intended as recommendations or as commentary on appropriate clinical practice.2021-01-1909 min
Ask Stago (english version)S2E1 - Whole Blood Viscoelastic Testing (VET)Welcome to Ask Stago, the weekly podcast about hemostasis.
This week, Cécile Hourquet and Audrey Carlo will discuss about viscoelastic testing and the usage of it with our expert Wim Houdijk.
Literature:
Hartert H. Blutgerinnungsstudien mit der Thrombelastographie, einem neuen Untersuchungsverfahren.Klin Wochenschr. 1948;26:577-583.
Sayce AC, Neal MD, Leeper CM. Viscoelastic monitoring in trauma resuscitation Transfusion. 2020;60 (Suppl 6):S33-S51.
Agarwal S, Abdelmotieleb M. Viscoelastic testing in cardiac surgery. Transfusion. 2020;60 (Suppl 6):S52-S60.
Tetsuro Sakai.Viscoelastic testing in liver transplantation. Transfusion. 2020;60 (Suppl 6):S61-S69.
Waters JH. The role of viscoelastic testing in the management of the parturient. Tra...2021-01-0510 min
Ask Stago (english version)#15 Disseminated Intravascular Coagulation (DIC) and fibrin related markersWelcome to Ask Stago, the weekly podcast for Hemostasis laboratory professionals.
This week, with our expert Paul Riley, Scientific Business Development Manager, Cécile Hourquet and Audrey Carlo will cover the usage of fibrin related markers in the diagnosis of disseminated intravascular coagulopathy.
Litterature:
Baglin T. Disseminated intravascular coagulation: diagnosis and treatment. BMJ 1996; 312: 683-7
Iba T, Di Nisio M, Thachil J, Wada H, Asakura H, Sato K, Kitamura N, Saitoh D. Revision of the Japanese Association for Acute Medicine (JAAM) disseminated intravascular coagulation (DIC) diagnostic criteria using antithrombin activity. Crit Care. 2016 Sep 14;20:287
Taylor FB Jr, Toh CH, Hoots WK, Wada H, Levi...2020-12-2208 min
Ask Stago (english version)#14 How to be more productive (Part. 3): WorkcellWelcome to Ask Stago, weekly podcast dedicated to providing expert answers to your expert questions in coagulation.
This week, thanks to their expert Alexandre Rousseaux, Cécile Hourquet and Audrey Carlo will question how to be more productive in the lab using a workcell.
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Content is scientific and technical in nature. It is intended as an educational tool for laboratory professionals and topics discussed are not intended as recommendations or as commentary on appropriate clinical practice.2020-12-1507 min
Ask Stago (english version)#13 The Lupus Anticoagulant diagnosis work upWelcome to Ask Stago, the weekly podcast dedicated to providing expert answers to your expert questions in coagulation.
This week, with our expert Lisa Gannon, product line manager, Cécile Hourquet and Audrey Carlo will question how to accurately perform an Lupus Anticoagulant diagnosis work up in the laboratory.
Sources:
Miyakis S, Lockshin MD, Atsumi T, Branch DW, Brey RL, Cervera R, Derksen RH, De Groot PG, Koike T, Meroni PL, Reber G, Shoenfeld Y, Tincani A, Vlachoyiannopoulos PG, Krilis SA. International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS). J Thromb H...2020-12-0809 min
Ask Stago (english version)#12 How to be more productive (Part. 2): the Lean and the Six sigmaWelcome to Ask Stago, The Podcast dedicated to provide expert answers to your expert questions in coagulation.
On today’s episode, thanks to our expert Andres Ramirez, discover the part 2 of our series “how to be more productive” with a special episode about Lean and Six sigma workflow analysis.
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Content is scientific and technical in nature. It is intended as an educational tool for laboratory professionals and topics discussed are not intended as recommendations or as commentary on appropriate clinical practice.2020-12-0109 min
Ask Stago (english version)#11 – Monitoring of UFH: APTT or Anti-Xa?Welcome to Ask Stago, The Podcast dedicated to provide expert answers to your expert questions in coagulation.
In our episode this week, we will discuss with François Depasse, our Clinical Development Director, about the monitoring of UFH and the appropriate tool to do it: APTT or anti-Xa activity?
Sources:
Johnson EA, Mullboy B. The molecular weight range of commercial heparin preparations. Carbohydr Res 1976; 51: 119-127
Hirsh J, Raschke R, Heparin and Low-molecular-weight heparin : the Seventh ACCP Conference on Antithrombotic and thrombolytic therapy. CHEST 2004; 126 (suppl 3): 188S-203S.
Basu D, Gallus A, Hirsh J, Cade J. A prospective study of...2020-11-2408 min
Ask Stago (english version)#10 How to be more productive (Part 1): implementation of a rules engineWelcome to Ask Stago, the weekly podcast for Hemostasis laboratory professionals.
In today’s episode, with our expert Draga Tchipeva, international application specialist, Cécile Hourquet and Audrey Carlo will start questioning how we can help the laboratory to become more productive with some middleware solutions: rules engines.
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Content is scientific and technical in nature. It is intended as an educational tool for laboratory professionals and topics discussed are not intended as recommendations or as commentary on appropriate clinical practice.2020-11-1708 min
Ask Stago (english version)#9 How to manage HIL samples in the coagulation laboratory?Welcome to Ask Stago, the weekly podcast for Hemostasis laboratory professionals. This week, with our expert Frédéric Brutto, product line manager, Cécile Hourquet and Audrey Carlo will question HIL interferences and how the coagulation laboratory can handle them.
Sources:
Lippi G et al., Interference of blood cell lysis on routine coagulation testing. Arch Pathol Lab Med. 2006;130(2):181-4
Woolley A et al., Effects of haemolysis, icterus and lipaemia on coagulation tests as performed on Stago STA-Compact-Max analyser. Int J Lab Hematol. 2016; 38(4): 375-88
Plebani M, Quality Indicators to Detect Pre-Analytical Errors in Laboratory Testing, Clin Biochem Rev 2012; 3: 85-88. ...2020-11-1007 min
Ask Stago (english version)#8 What are sensitivity and specificity performances of a diagnostic assay?Welcome to Ask Stago, the weekly podcast for Hemostasis laboratory professionals
In today’s episode, with Lydie Nicoud, Director of Design and Biological Applications development, Cécile Hourquet and Audrey Carlo will try to better understand sensitivity and specificity of a diagnostic test, through some examples.
Sources:
CLSI, Quantitative D-dimer for the Exclusion of Venous Thromboembolic Disease, CLSI document H59-A, Wayne PA; Clinical Laboratory Standards Institute 2011
Valentine Minet, Jean-Michel Dogné, and François Mullier, Functional Assays in the Diagnosis of Heparin-Induced Thrombocytopenia: A Review Molecules 22, no. 4 (April 11, 2017): 617, https://doi.org/10.3390/molecules22040617.
Cuker A, Arepally GM, Chong BH, et al...2020-11-0306 min
Ask Stago (english version)#7 How to determine the mean normal prothrombin timeWelcome to Ask Stago, the weekly podcast for Hemostasis laboratory professionals.
In today’s episode, we will provide you our best tips and tricks to calculate the mean normal prothrombin time for INR assay. To do so, Cécile Hourquet and Audrey Carlo are pleased to welcome Arnaud Rouvière, Manager of the International Application Engineer team of Stago.
Source: WHO technical report series ; no. 979, 2013
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Content is scientific and technical in nature. It is intended as an educational tool for laboratory professionals and topics discussed are not intended as recommendations or as commentary on appropriate2020-10-2707 min
Ask Stago (english version)#6 Cybersecurity & Clinical laboratoriesWelcome to Ask Stago, the Podcast providing expert answers to your expert questions.
In today’s episode, our cybersecurity referent Alexandre Rousseaux will explain us how cybersecurity is impacting lab practices every day and why we are all talking about it.
Follow us on LinkedIn In or Twitter
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Content is scientific and technical in nature. It is intended as an educational tool for laboratory professionals and topics discussed are not intended as recommendations or as commentary on appropriate clinical practice.2020-10-2006 min
Ask Stago (english version)#5 World Thrombosis Day 2020 - Part. 1 DebraWelcome to Ask Stago, The Podcast dedicated to provide expert answers to your expert questions in coagulation.
Today episodes are broadcasted from October 13, which is the World Thrombosis Day. Our episodes are thus dedicated to raise awareness about thrombosis symptoms and management, through the interview of 3 “thrombosis survivors”: Debra Bryant, honorable mention recipient of the WTD 2020 Ambassador of the Year Award, Todd Robertson, one of the most active WTD Ambassadors within the US, and Chris Pugh, who lives in the UK and very recently started his "living with a clot" journey.
Get involved in the WTD movemen...2020-10-1310 min
Ask Stago (english version)#5 World Thrombosis Day 2020 - Part. 2 ToddWelcome to Ask Stago, The Podcast dedicated to provide expert answers to your expert questions in coagulation.
Today episodes are broadcasted from October 13, which is the World Thrombosis Day. Our episodes are thus dedicated to raise awareness about thrombosis symptoms and management, through the interview of 3 “thrombosis survivors”: Debra Bryant, honorable mention recipient of the WTD 2020 Ambassador of the Year Award, Todd Robertson, one of the most active WTD Ambassadors within the US, and Chris Pugh, who lives in the UK and very recently started his "living with a clot" journey.
Get involved in the WTD movemen...2020-10-1309 min
Ask Stago (english version)#5 World Thrombosis Day 2020 - Part. 3 ChrisWelcome to Ask Stago, The Podcast dedicated to provide expert answers to your expert questions in coagulation.
Today episodes are broadcasted from October 13, which is the World Thrombosis Day. Our episodes are thus dedicated to raise awareness about thrombosis symptoms and management, through the interview of 3 “thrombosis survivors”: Debra Bryant, honorable mention recipient of the WTD 2020 Ambassador of the Year Award, Todd Robertson, one of the most active WTD Ambassadors within the US, and Chris Pugh, who lives in the UK and very recently started his "living with a clot" journey.
Get involved in the WTD movemen...2020-10-1309 min
Ask Stago (english version)#4 D-Dimer and its cut-offs for VTE exclusionWelcome to Ask Stago, the Podcast providing expert answers to your expert questions.
In today’s episode, with François Depasse our Clinical Development Director, we will discuss the selection of a cut-off for D-dimer assay in venous thromboembolism exclusion diagnosis.
Sources: Pernod G, Maignan M, Marlu R. Questioning the use of an age-adjusted D-dimer threshold to exclude venous thromboembolism: analysis of individual patient data from two diagnostic studies: comment. J Thromb Haemost 2016; 14: 2553–4.
Stavros V Konstantinides, Guy Meyer, Cecilia Becattini, Héctor Bueno, Geert-Jan Geersing, Veli-Pekka Harjola, Menno V Huisman, Marc Humbert, Catriona Sian Jennings, David Jiménez...2020-10-0607 min
Ask Stago (english version)#3 eIQC and EQA: benefits and differencesWelcome to Ask Stago, the Podcast providing expert answers to your expert questions.
In today’s episode, thanks Minh-Lan Nguyen, product line manager, we will help you to differentiate and understand the goal of the externalized internal quality control (eIQC) and external quality assessment programs (EQA).
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Content is scientific and technical in nature. It is intended as an educational tool for laboratory professionals and topics discussed are not intended as recommendations or as commentary on appropriate clinical practice.2020-09-2908 min
Ask Stago (english version)#2 Coagulation abnormalities in COVID-19 patientsWelcome to Ask Stago, the podcast providing expert answers to your expert questions.
In this week ‘s episode with our expert François Hamon, we will provide you information about how infection with COVID-19 affects coagulation and how these coagulation abnormalities should be monitored.
Sources: Tang N, Li D, Wang X, Sun Z. Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia. J Thromb Haemost 2020;18:844–7.
Moores LK, Tritschler T, Brosnahan S et al, Prevention, Diagnosis, and Treatment of VTE in Patients With Coronavirus Disease 2019, CHEST Guideline and Expert Panel Report, CHEST 2020; 15...2020-09-2409 min