Shows
Science FareFrom DNA mutations to cancer with a focus on leukemia with Pat BrownPat Brown talks about his path to becoming a physician and scientist, the importance of a bench-to-bedside-back-to-bench approach in drug development, and targeted cancer therapy. Using his work in leukemia as an example, Pat talks about how changes at the level of DNA sequence change proteins and can lead to the development of cancer, and how scientists can use this knowledge to develop specific cancer treatments. Works cited in this conversation:The Emperor of All Maladies: A Biography of Cancer by Siddhartha MukherjeeJanet Rowley and her work on cancer genetics ...2024-12-201h 07Science FareFrom DNA mutations to cancer with Pat Brown MINI episodeFocusing on leukemia as an example, Pat Brown tells us how changes in the DNA sequence of a gene can result in cancer. This connects to one of the Next Generation High School Science Standards in Life Science, which states that students should be able to construct an explanation based on evidence for how the structure of DNA determines the structure of proteins which carry out the essential functions of life through systems of specialized cells. Hosted on Acast. See acast.com/privacy for more information.2024-12-1612 minScience FareA new take on diffusion with Naomi Oppenheimer and Matan Yah Ben ZionNaomi Oppenheimer and Matan Yah Ben Zion talk about their path to becoming physicists and their latest work — a look at the diffusion of a substance made of repulsive particles. Most often when high school students learn about diffusion, the assumption is that the particles feel no attractions to each other. When you place a drop of dye into a flask of water, the dye spreads. Microscopically, the particles of dye and water bounce off each other due to thermal motion but we assume they experience no significant attraction or repulsion to each other.B...2024-12-0555 minScience FareA New Take on Diffusion MINI EpisodeSeason 2, Episode #4. In this mini episode, Naomi Oppenheimer and Matan Yah Ben Zion talk about their path to becoming physicists and their latest work — a look at the diffusion of a substance made of repulsive particles. Most often when high school students learn about diffusion, the assumption is that the particles feel no attractions to each other. When you place a drop of dye into a flask of water, the dye spreads. Microscopically, the particles of dye and water bounce off each other due to thermal motion but we assume they experience no sign...2024-12-0210 minScience FareCarbon Monoxide: Foe . . . . or friend? Leo Otterbein on the potential of carbon monoxide in medicineOur guest today is Dr. Leo Otterbein, a professor of surgery at Beth Israel Deaconess Medical Center and Harvard Medical School. Leo’s research group focuses on the role of carbon monoxide as a therapeutic agent in medical applications ranging from organ transplant to infection to cancer. Inhaled carbon monoxide is currently in numerous FDA trials based in large part due the research in Leo's lab over the past decade. Leo is also chair of the Beth Israel Deaconess Medical Center (BIDMC) Institutional Animal Care and Use Committee. As the site miner for the BIDMC Center for the Integration of...2024-11-1357 minScience FareHelping Communities Get More Physical Activity with Dan HatfieldSeason 2, Episode #2. Dr. Dan Hatfield is a senior public health researcher at FHI360 with 15 years of experience developing, evaluating, and replicating community and behavioral interventions promoting healthy eating and physical activity, particularly in children, adolescents, and families. Previously, as a Research Assistant Professor at Tufts University, he served as principal or co-investigator on 13 federal and foundation-funded research grants, and he taught graduate courses in behavioral theory, health communications, and public health. His subject-matter expertise spans diverse domains, including nutrition, physical activity, obesity prevention, health communications, and theory-based intervention design.Dan talks with us a...2024-10-3048 minScience FareUsing Biophysics to See the Forces at Work Inside the Cell with Mike ShelleySeason 2, Episode #1. Mike Shelley is an applied mathematician who uses modeling and simulation to better understand the physics and biology of complex systems. He is the director of the Center for Computational Biology, which is part of the Flatiron Institute — the scientific research arm of the Simons Foundation located in NYC. He also co-founded and co-directs the Courant Institute’s Applied Mathematics Laboratory at New York University.Today, Mike is going to talk about elucidating how things in the cell find their proper place. Most listeners likely know that the cell is the basic...2024-10-1644 minScience FareHigh School Science Standard: Engaging in Argument from EvidenceIn this episode, I give a quick summary of the interview with Christie del-Castillo Hegyi and Jody Segrave Daly that aired on Science Fare on Monday, June 17, 2024. Christie and Jody are the founders of the Fed is Best Foundation and authors, along with Lynnette Hafken, of the forthcoming book, Fed is Best. In today’s episode, we talk about:*The Next Generation High School Science Standard entitled, “Engaging in Argument from Evidence.” In this standard, high school students are asked to evaluate the claims, evidence, and reasoning behind currently accepted explanations or solutions to dete...2024-06-2019 minScience FareFed is Best with Christie del-Castillo Hegyi and Jody Segrave-DalyIn this episode of Science Fare, I interview Christie del-Castillo Hegyi and Jody Segrave-Daly, founders of the Fed is Best Foundation and authors, along with Lynnette Hafken, of the forthcoming book, Fed is Best. Links mentioned in the episode:Fed is Best FoundationFed is Best BookNew York Times Parenting article on How to Deal with Low Breastmilk SupplySibling study on breast- and formula-fed babies and outcomes (appearing in Social Science & Medicine, 2014)In the interview, we talk about:*Christie’s a...2024-06-1757 minScience FareLisa Ammirati on Linking High School Science to the World Beyond the ClassroomLisa Ammirati, high school science teacher and chair of the science department at Abington Friends School talks to us about her career as a science teacher and strategies to integrate classroom curriculum with events in the broader world.In this conversation, we talk about:*Lisa’s career in teaching [3:25];*What it’s like being a department chair [4:58];*What is uniquely special about teaching 10th grade chemistry [6:30];*What Lisa has done in her classroom to connect the curriculum to the broader world [8:35];*Why the Flint, MI chem...2024-01-2436 minScience FarePart 2 of Jill Herschleb on Discovery-Based Research with Single-Cell GenomicsJill Herschleb, senior director of cell biology at 10x Genomics, talks about her path as a scientist and her work in building the tools that have helped make single-cell genomics the robust and flexible technology it is today. Here is an informative video on single cell genomics and its use in the effort to make a comprehensive human cell map (aka, the Human Cell Atlas). In Part 2 of this conversation, we discuss:*the idea of a cell as a test tube in single-cell genomics, and setting up massively parallel (millions an...2024-01-1744 minScience FareJill Herschleb on Discovery-Based Research with Single-Cell GenomicsEpisode #8.Jill Herschleb, senior director of cell biology at 10x Genomics, talks about her path as a scientist and her work in building the tools that have helped make single-cell genomics the robust and flexible technology it is today. Here is an informative video on single cell genomics and its use in the effort to make a comprehensive human cell map (aka, the Human Cell Atlas). In Part 1 of this conversation, we discuss:*How Jill got interested in science as a kid [2:30]*Jill’s grad scho...2024-01-1034 minScience FareHigh School Science HighlightsAt the halfway point of Season One of the Science Fare podcast, let’s have a listen to this special High School Science highlights episode — a collection of clips from previous episodes when the scientists link their work to the high school science learning standards. We have Hashim Al-Hashimi (Episodes 1 and 2) talking about how complexity evolves, Jamie Morton (Episodes 3 and 4) talking about the scientific process and feedback in biological systems, and Kelly Knudson (Episode 5 and 6) talking about how strontium gets into bones. Specific timestamps:*Hashim Al-Hashimi: New York state high school curriculum in Life Scien...2024-01-0322 min
Reclaiming Yourself with Suzanne KeatleyThe Importance of Fitness as you Age - Susan BiddleIs your body starting to feel more frail? It's time to get more serious about your health.
Susan is 63 years old and after her partner passed last year, she decided to try and do something about her body since she wasn't feeling like her best self. It's one of the best decisions she's made, becoming a part of her weekly routine.
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About Suzanne
During her coaching and mentoring work through Fitology Hub, Suzanne Keatley has met some truly awesome humans... humans who deserve to have their stories heard. Through these shared co...2023-12-1536 minScience FarePart 2 of Kelly Knudson on Using Archaeological Chemistry to Help Understand Feasting at a 2000-year-old Site in PeruPart 2 of the conversation with Kelly Knudson, professor of Anthropology in the School of Human Evolution and Social Change at Arizona State University, and director of the Center for Bioarchaeological Research and the Archaeological Chemistry Laboratory, who talks to us about archaeological chemistry, her path as an archaeological chemist, and about a paper she and others published in PNAS entitled “Feasting and the evolution of cooperative social organizations circa 2300 B.P. in Paracas culture, southern Peru,” in which the chemical isotope data help determine where objects at a feasting site came from, and from there, lead to inferences about the...2023-12-1328 minScience FareKelly Knudson on Using Archaeological Chemistry to Help Understand Feasting at a 2000-year-old Site in Peru -- Part 1Episode #5.Kelly Knudson, professor of Anthropology in the School of Human Evolution and Social Change at Arizona State University, and director of the Center for Bioarchaeological Research and the Archaeological Chemistry Laboratory, talks to us about archaeological chemistry, her path as an archaeological chemist, and about a paper she and others published in PNAS entitled “Feasting and the evolution of cooperative social organizations circa 2300 B.P. in Paracas culture, southern Peru,” in which the chemical isotope data help determine where objects at a feasting site came from, and from there, lead to inferences about the evolution of s...2023-12-0631 minScience FarePart 2 of Jamie Morton on Finding Associations Between the Microbiome and AutismPart 2 of the conversation with Jamie Morton, scientist and founder of Gutsy Analytics, who talks about his June 2023 paper in Nature Neuroscience entitled, “Multi-level analysis of the gut-brain axis shows autism spectrum disorder-associated molecular and microbial profiles,” in which Jamie and 42 other authors re-analyzed prior datasets to discover new connections between the human gut microbiome and autism.For a primer on the human microbiome, check out this 2020 review piece that appeared in Nature Medicine: “Current understanding of the human microbiome.”We discuss:*Implications of this work for future studies on autism —...2023-11-2926 minScience FareJamie Morton on Finding Associations Between the Microbiome and Autism -- Part 1Jamie Morton, scientist and founder of Gutsy Analytics, talks about his June 2023 paper in Nature Neuroscience entitled, “Multi-level analysis of the gut-brain axis shows autism spectrum disorder-associated molecular and microbial profiles,” in which Jamie and 42 other authors re-analyzed prior datasets to discover new connections between the human gut microbiome and autism.For a primer on the human microbiome, check out this 2020 review piece that appeared in Nature Medicine: “Current understanding of the human microbiome.”We discuss:*Introduction of the terms “human gut microbiome” and “autism” [1:20]*Jamie’s background as a scientist [4...2023-11-1530 minScience FarePart 2 of Hashim Al-Hashimi on Why We Should See Biological Molecules as Computing MachinesHere is Part 2 of the conversation with Hashim Al-Hashimi, professor of biochemistry and molecular physics at Columbia University, who talks about his March 2023 paper in the Proceedings of the National Academy of Sciences (PNAS) entitled, “Turing, von Neumann, and the computational architecture of biological machines,” in which he writes about an opportunity for better understanding biological problems: seeing biological molecules as computing machines. We discuss:*Quick recap of Part 1 [1:05];*DNA polymerase and its transition states (spoiler alert: it’s like Pac-Man) [1:57];*The different shapes, or contortions, of biomolecules can be seen...2023-11-0837 minScience FareHashim Al-Hashimi on Why We Should See Biological Molecules as Computing Machines -- Part 1Hashim Al-Hashimi, professor of biochemistry and molecular physics at Columbia University, talks about his March 2023 paper in the Proceedings of the National Academy of Sciences (PNAS) entitled, “Turing, von Neumann, and the computational architecture of biological machines,” in which he writes about an opportunity for better understanding biological problems: seeing biological molecules as computing machines. In Part 1 of our conversation, we discuss:*Hashim’s background as a scientist [1:05];*Prelude to the problem: the late Nobel laureate Sydney Brenner’s idea that we are drowning in data [3:55];*How Hashim got involved...2023-11-0129 minScience FareWelcome to Science Fare with Susan KeatleyWelcome to the Science Fare podcast!On the Science Fare podcast, I aim to bring you conversations with scientists doing fascinating, cutting-edge work on all kinds of interesting phenomena, ranging from physics to chemistry to biology, and even the nature of science itself. Each conversation is split into two parts, and at the end of part two, we'lll draw connections between the scientist's research, and one or two high school science learning standards from that scientist's state.Tune in for some Science Fare! Hosted on Acast. See acast.com/privacy...2023-10-2601 min
Our Power Is Within: Heal Chronic Illness & Pain75: Panel Discussion on Movement as Medicine with Susan, Glenda, & AllisonToday I have a special treat! Not one guest - but three! Welcome Susan P, Glenda C, and Allison to the show for a panel discussion on all things movement (exercise) and healing! These 3 ladies are all DNRS brain retrainers, who also have been participating in my movement classes for about the last year. They join me to discuss all things movement. We talk about when they felt ready to incorporate movement into their retraining experience. How movement has impacted their healing, movement/exercise goals, as well as how movement has even created positive mental shifts. We have so...2022-02-011h 21
Managing Your PracticeBuying, Selling, or Merging: Advisors’ Perspectives on Mergers and AcquisitionsWhether you’re seeking an external partner for the purpose of retirement, succession planning, or taking your business to the next level, the merger and acquisition (M&A) process can be daunting for any advisory firm. How do you find the right partner? How do you ensure a good cultural fit for your staff and your clients? What does integration entail post transaction? Catherine Williams, Dimensional’s Head of Practice Management, is joined by Susan Strausbaugh of Buckingham Strategic Wealth and Karen Keatley of Modera Wealth Management as they discuss successful M&A experiences at their firms.2020-11-1833 min