Shows
The ReProgramPeptides for Healing & Performance: BPC-157, TB-500 & Growth Hormone ExplainedIn this episode of Peptides 101, Dr. George Murphy delves into the application of peptide science in real-world scenarios, focusing on the distinction between peptides as signals versus supplements. He discusses the compelling nature of healing peptides, particularly BPC 157 and TB 500, and the importance of understanding the scientific evidence behind their use. The conversation emphasizes the gap between anecdotal claims and clinical data, urging listeners to approach peptide use with caution and humility. The episode concludes with a preview of future discussions on peptides related to aging and longevity.Keywordspeptides, healing, recovery, BPC 157, TB 500, growth hormone, regenerative medicine...
2026-02-0928 minThe ReProgramPeptides 101: The Biology Behind the HypeThe ReProgram Episode 8A: The first in a 3 part series In this episode, Dr. George Murphy delves into the world of peptides, exploring their scientific basis, the misconceptions surrounding them, and the importance of understanding their structure and function. He discusses the differences between natural and synthetic peptides, the manufacturing process, and the potential risks associated with peptide use. The conversation aims to provide clarity in a landscape filled with hype and misinformation, setting the stage for future discussions on specific peptides and their claims.Keywordspeptides, science, health, longevity, biochemistry, molecular biology...
2026-01-2618 minThe ReProgramOzempic Isn’t a Weight-Loss Drug | The Real Science of GLP-1sThe ReProgram Episode 7In this episode of the Reprogram Podcast, Dr. George Murphy explores the rise of GLP-1 drugs like Ozempic, Wegovy, and Mounjaro, discussing their mechanisms, effects on metabolism, and implications for aging and healthspan. He emphasizes that these drugs are not merely weight loss solutions but agents that act on multiple organs to reprogram how the body regulates energy and hunger. The conversation also addresses the potential benefits and drawbacks of these drugs, including their impact on muscle mass and overall health.KeywordsGLP-1 drugs, Ozempic, Wegovy, Mounjaro, weight loss, metabolic...
2026-01-1216 minThe ReProgramInside the Aging Brain: Dementia, Resilience, and What We Can Do!Episode 6 This episode of the ReProgram podcast, featuring Dr. Benjamin Wolozin, delves into the complexities of neurodegenerative diseases and brain aging, with a focus on Alzheimer's. The discussion covers the diversity of these diseases, diagnostic challenges, and the future of research. The conversation is enriched with personal stories and expert insights, providing a comprehensive understanding of the topic.Keywordsmemory, aging, dementia, Alzheimer’s, cognitive health, sleep, phospho-tau, biomarkers, cognitive decline, health tests, longevityTakeawaysUnderstanding the diversity of neurodegenerative diseases is crucial.Early diagnosis of Alzheimer's remains a significant ch...
2025-12-2937 minThe ReProgramThe Rise of Longevity ClinicsEpisode 5 In this episode of the Reprogram podcast, Dr. George Murphy explores the burgeoning world of longevity clinics, particularly in Thailand, where anti-aging treatments have become mainstream. He delves into the science behind stem cell therapies, the rise of IV drip bars, and the booming aesthetic dermatology industry. The conversation highlights the accessibility and affordability of these treatments in Thailand, while also addressing the potential pitfalls and the importance of navigating this landscape with caution. Ultimately, the episode emphasizes the need for a balanced understanding of longevity science and the commercial industry surrounding it, advocating for patient...
2025-12-1629 minThe ReProgramWhy Eating Less Slows Aging | Caloric Restriction & Longevity with Dr. Rozalyn AndersonEpisode 4 In this episode of the Reprogram Podcast, Dr. George Murphy hosts Dr. Rozalyn Anderson, a leading expert in caloric restriction and metabolism and how they impact healthful aging. They delve into the science of aging, focusing on caloric restriction and its impact on longevity. Dr. Anderson shares her journey from yeast genetics to studying aging in animal models, and finally, to applying what was learned to humans, highlighting the metabolic processes that contribute to aging and how caloric restriction can delay age-related diseases. The discussion also covers the potential of geroprotectors like rapamycin, the possibilities of...
2025-12-0130 minThe ReProgramWhat Centenarians Teach Us About Living Longer | Dr. Tom PerlsEpisode 3 In this episode of the Reprogram podcast, Dr. George Murphy hosts Dr. Tom Perls, a leading expert in human exceptional longevity. They discuss Dr. Perls' journey into gerontology, the New England Centenarian Study, and the factors contributing to exceptional longevity. The conversation covers the genetic and environmental influences on aging, the role of centenarians in understanding longevity, and practical advice for living a centenarian-like life.Keywordslongevity, centenarians, aging, health, resilience, exceptional aging, gerontology, aging research, genetics, healthspanTakeawaysDr. Tom Perls shares his journey into gerontology and exceptional...
2025-11-1755 minThe ReProgramWhat Is Aging—And Can Science Really Reverse It?Episode 2 In this episode of the Reprogram podcast, Dr. George Murphy explores the enigmatic topic of aging, discussing its definitions, cultural significance, and the latest scientific advancements aimed at understanding and potentially reversing the aging process. The conversation delves into the historical obsession with aging, the current state of research, and the implications of emerging therapies.Keywordsaging, science, medicine, longevity, epigenetics, biological clocks, senescence, gene therapy, regenerative medicine, immortality, geroscienceTakeawaysAging is a complex and mysterious process and is defined variably by different scientists.Modern science is exploring...
2025-11-1713 minThe ReProgramStem Cells & Regenerative Medicine: What the Science Actually SupportsEpisode 1 In this episode of the Reprogram podcast, Dr. George Murphy and Dr. Gustavo Mostoslavsky delve into the world of stem cells and regenerative medicine. They discuss the fundamental properties of stem cells, their classifications, and the controversies surrounding their use in treatments. The conversation highlights the groundbreaking discovery of induced pluripotent stem cells (iPSCs) and their potential therapeutic applications, as well as the emerging field of organoids. The episode emphasizes the importance of understanding the science behind stem cells, the ethical implications, and the need for patience as research progresses towards practical applications.Keywords
2025-11-1747 minThe ReProgramIntroducing The ReProgram PodcastEpisode 0In the premier episode of The ReProgram podcast, Dr. George Murphy introduces the concept of reprogramming oneself for resilience against disease and disability. He shares his existential crisis about focusing on disease treatment rather than prevention, leading to a new approach centered on studing dynamic resilience, or our ability to robustly respond to insult and injury. The episode also outlines topics for future discussions, including the history and use of stem cells in regenerative medicine, exceptional longevity and centenarians, and the realities of age reversal.Keywordsreprogramming, resilience, iPSCs, stem cells, disease...
2025-11-1006 min