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Toby Jeffcote

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Coda ChangeCoda ChangeResearch in TBI: Separating Apples from ApplesThis presentation was delivered by Toby Jeffcote as part of the Critical Care Update Workshop at CODA22, which took place in Melbourne in September 2022. For more information about the CODA Project, go to: https://codachange.org/ 2024-02-1924 minNeuro ResusNeuro ResusKetamine for Brain InjuryHistorically, when it came to brain injury, ketamine had a bad rap. Much of that dogma was dispelled in the last 20 years, and ketamine is now frequently used as an induction agent in acute brain injury, especially traumatic brain injury, partially due to the favorable effects on haemodynamics.  However a new application of ketamine is now being explored - whether ketamine may be able to reduce secondary brain injury. In this talk Toby Jeffcote initially takes us through all the sedatives currently used in brain injury and the evidence to support their use. He then c...2024-01-2436 minNeuro ResusNeuro ResusCortical Spreading Depolarisation in Neurological Disease - An IntroductionCortical spreading depolarization (CSD) is a spreading loss of ion homeostasis, altered vascular response, change in synaptic architecture, and subsequent depression in electrical activity following an inciting neurological injury. This presentation was delivered by Toby Jeffcote at CODA2022. Want more content about CSD? Visit neuroresus.com or subscribe to be notified of new podcast releases via email. To express your interest in attending the 2024 Neuroresus live course, click here. 2024-01-2225 minOsler PodcastsOsler PodcastsPRECISION-TBITraumatic brain injury is a significant problem, affecting patients of all ages across the globe.  Despite this, relatively little hard evidence supports the interventions commonly used in practice. Research in this area remains challenging, with many barriers to the traditional large-scale randomised controlled trial.  Perhaps alternative sources of evidence are required. In this podcast from the 24th annual ANZICS-CTG meeting in Noosa, Toby Jeffcote joins Todd to discuss these limitations, and how "big data" may provide the solution.See omnystudio.com/listener for privacy information.2022-05-1223 min