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Data in Biotech
From Tissue to Mechanism to Decision: Building AI for Computational Oncology
In this episode of Data in Biotech, host Ross Katz sits down with Arvind Rao, Professor of Computational Medicine and Bioinformatics at the University of Michigan, for a discussion on the gap between what biomedical AI can do and what it can reliably be trusted to do in clinical practice. Arvind's research sits at the intersection of computational oncology and AI governance and his lab works across H&E histopathology, multiplex immunofluorescence, spatial transcriptomics, and single-cell RNA sequencing, not just to build predictive models, but to understand the full lifecycle from data to model to inference, and to ask...
2026-06-02
46 min
Data in Biotech
Cavities in the Data: Building FDA-Cleared AI for Dental Imaging with Overjet
In this episode of Data in Biotech, host Ross Katz sits down with Sadegh Salehi, Director of Research and Principal Scientist at Overjet, to explore what rigorous model evaluation actually looks like when the stakes are clinical. Overjet builds FDA-cleared vision models that detect and quantify dental disease across billions of X-ray images from thousands of practices - a data problem with a staggering number of dimensions. Thirty-two teeth per adult patient, each with different morphology. Multiple image types capturing different anatomy. Fifteen to twenty sensor manufacturers producing perceptually distinct images, each with different contrast, resolution, and n...
2026-05-13
58 min
Data in Biotech
Data as a Moat: Why Biotech's Most Valuable Asset is Buried in a Hard Drive
In this episode of Data in Biotech, host Ross Katz sits down with Jesse Johnson, founder of Merelogic, a software consulting firm specializing in data infrastructure for biotech organizations. Jesse brings a rare perspective to the conversation: having built data systems at Google where engineers control the data collection function end to end, before moving into biotech, where the biology does what it wants and bench scientists, not engineers, generate the data. The result is a grounded, pragmatic take on one of the most consequential and underappreciated questions in life sciences right now: as bio fo...
2026-04-30
42 min
Eventual Consistency | Your Reality Check on What's Actually Happening in Data
How Software Supply Chain Risk Became Everyone's Problem
The threat isn't coming from outside your perimeter. It's already inside, embedded in the open source libraries your engineers pulled in last quarter, the routers running on your network, the security tooling sitting in your CI/CD pipeline. In this episode of Eventual Consistency, host James Winegar is joined by Jamil Bou Khair, founder and CEO of Firezone, and Brian Manifold, senior full stack engineer at Firezone, to unpack what software supply chain security actually looks like in practice and why most enterprises are still building their defenses for a threat model that no longer reflects reality.
2026-04-23
34 min
Data in Biotech
How Phage Therapy is Scaling to Meet Antibiotic Resistance with Jessica Sacher
Phage therapy is stepping into the spotlight as antibiotic resistance rises - and Jessica Sacher is helping lead the charge. In this episode, Ross Katz speaks with Jessica, Co-Founder of Phage Directory and Staff Scientist at Stanford, about sourcing phages, operationalizing therapy, and predicting efficacy through data. This conversation explores how personalized phage therapy works, its scalability, and the data challenges shaping its future. What You'll Learn in This Episode: Why phage therapy is a promising solution to antibiotic-resistant infectionsHow Phage Directory connects researchers and clinicians to accelerate treatmentWhat operational hurdles exist in scaling pers...
2025-04-30
59 min
Data in Biotech
Targeting Transcription Factors with AI, featuring Will Fondrie from Talus Bio
How do you drug the undruggable? In this episode of Data in Biotech, Ross Katz sits down with Will Fondrie, Head of Data Science and Engineering at Talus Bio, to explore how machine learning, mass spectrometry, and innovative computational models are transforming drug discovery. Learn how Talus Bio is targeting transcription factors—once considered out of reach—with scalable, high-impact data science. What You'll Learn in This Episode Why transcription factors are historically hard to drug and how Talus Bio is changing thatHow mass spectrometry offers high-throughput, unbiased views of protein-DNA interactionsThe role of reco...
2025-04-16
46 min
Data in Biotech
How AI Can Increase Clinical Trial Efficiency with Patrick Leung from Faro Health
How can AI improve clinical trials and accelerate drug development? In this episode of Data in Biotech, Ross Katz sits down with Patrick Leung, CTO of Faro Health, to explore how AI-driven tools are reshaping clinical trial design. Patrick shares insights into document generation, patient burden analysis, and AI governance in biotech. Learn how Faro Health is developing clinical protocols and leveraging AI to optimize trial success while ensuring regulatory compliance. Whether you're in biotech or healthcare, this conversation offers valuable takeaways on the future of AI in increasing clinical trial efficiency. What You...
2025-03-19
39 min