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SOS AMS PodcastSOS AMS PodcastApplied Cases: Bacteremia 2This episode of the SOS AMS podcast is a continuation of the Bacteremia part 1 podcast. In this episode, our hosts apply the systematic approach to bacteremia discussed in the previous podcast to 3 patient cases. Relevant references can always be accessed at the provided hyperlink.   The learning objectives for the podcast are: Case 1: Viridans group Strep “bacteremia” 1 of 2 sets in a patient admitted with AECOPD Case 2: E. coli bacteremia secondary to pyelonephritis Case 3: Staph aureus bacteremia, unclear source Stock Media provided by raspberrysounds / Pond5 2022-09-2516 minSOS AMS PodcastSOS AMS PodcastBacteremiaIn this episode of the SOS AMS podcast, Julia and Nicki take a closer look at the management of bacteremia. They discuss interpretation of blood culture results, including distinguishing between contaminant and true pathogen, the clinical utility of time to positivity, and the identification of high risk bacteremias. They discuss a systematic approach to managing patients with bacteremia, and evaluation for sources of infection. They then make specific mention of Staphylococcus aureus bacteremia and the four-pronged bundle of care for Staphylococcus aureus bacteremia as well as discussing the rationale for that bundle. Relevant references can be accessed at the...2022-09-2520 minSOS AMS PodcastSOS AMS PodcastSepsis NYDThis episode of the SOS AMS podcast focuses on the ID/AMS side of sepsis and septic shock. Our hosts distinguish sepsis and septic shock from infection with systemic features, and bacteremia, both of which are commonly incorrectly referred to as sepsis in practice. They discuss an approach to identifying the source of sepsis in a patient with sepsis NYD, with emphasis on localizing symptoms, investigations, and what to do in the absence of localizing symptoms. They discuss the challenge in finding a balance between good stewardship and the use of aggressive antimicrobial therapy given the high mortality associated...2022-09-2526 minSOS AMS PodcastSOS AMS PodcastIntraabdominal Infections (IAI)This episode of the SOS AMS podcast focuses on the pathophysiology, diagnosis, and management of various community-onset intraabdominal infections. Infections discussed include cholecystitis, cholangitis, diverticulitis, acute appendicitis, pancreatitis, and liver abscess. Our hosts end the podcast by applying principles discussed to a patient case, going from differential diagnosis to management. Check out the clinical decision-making matrix for a summary of our top 3 differential diagnoses, as well as the relevant references at the provided hyperlinks. The learning objectives for this podcast are as follows: Contrast the pathophysiology of cholecystitis, cholangitis, diverticulitis, acute appendicitis, pancreatitis, and liver abscess.  L...2022-09-2523 minSOS AMS PodcastSOS AMS PodcastUrinary Tract Infections (UTI)This episode of the SOS AMS podcast focuses on the diagnosis, microbiology, and management of urinary tract infections, including cystitis, pyelonephritis, and catheter-associated UTIs. Our hosts also discuss the pressures in practice that lead to over-diagnosis of UTIs, a significant contributor to antibiotic resistance. They then end the podcast by applying the principles discussed to two patient cases, addressing common practice issues that arise when dealing with patients with suspected urinary tract infection.  Relevant references can be accessed at the provided hyperlink, and we would encourage taking a read through the excellent 3 page article written by Dr. Tom Finucane o...2022-09-2530 minSOS AMS PodcastSOS AMS PodcastDiabetic Foot Infections (DFI)This episode of the SOS AMS podcast focuses on the diagnosis, microbiology, and management of diabetic foot infections, specifically in the setting of chronic ulcers. Julia and Nicki discuss important considerations for obtaining and interpreting cultures in this setting, as well as the role played by specific microbes like Pseudomonas, Enterococcus, and MRSA. They then apply the principles discussed to two patients presenting with differing severity of infection. Relevant references can always be accessed at the provided hyperlink.   The learning objectives for this podcast are as follows: Describe the pathophysiologic processes that lead to d...2022-09-2517 minSOS AMS PodcastSOS AMS PodcastSkin and Soft Tissue Infections (SSTI)In this episode of the SOS AMS podcast, our hosts discuss the diagnosis, microbiology, and management of cellulitis. They describe clinical features that could be suggestive of a necrotizing soft tissue infection, to highlight when we would want to obtain a stat surgical consultation. They end the podcast by applying principles discussed to a patient case, like always, going from differential diagnosis to management. Check out the clinical decision-making matrix for a summary of our top 3 differential diagnoses, as well as the relevant references in the provided hyperlinks.   The learning objectives for this podcast are a...2022-09-2524 minSOS AMS PodcastSOS AMS PodcastHospital Acquired Pneumonia (HAP)This episode of the SOS AMS podcast focuses on the diagnosis and management of hospital-acquired pneumonia (HAP). Our hosts discuss the pathogenesis, microbiology, and treatment of HAP, with a brief discussion of when we would empirically cover MRSA as opposed to just MSSA. They then apply the principles discussed to a patient case, going from differential diagnosis to management. Check out the clinical decision-making matrix for a summary of our top 3 differential diagnoses, as well as the relevant references at the provided hyperlinks.   The learning objectives for this podcast are as follows: Rationalize antimicrobial s...2022-09-2520 minSOS AMS PodcastSOS AMS PodcastCommunity Acquired Pneumonia (CAP)During this episode of the SOS AMS podcast, Julia and Nicki dive into  the diagnosis and management of community-acquired pneumonia (CAP). They discuss the pathogenesis, microbiology, and treatment of CAP, with a brief discussion of the role of atypical pathogens. Our hosts then apply principles discussed to a patient case, going from differential diagnosis to management. Check out the clinical decision-making matrix for a summary of our top 3 differential diagnoses, as well as the relevant references at the hyperlinks provided.   The learning objectives for this podcast are as follows: Identify the mechanism by which pa...2022-09-2520 minSOS AMS PodcastSOS AMS PodcastAcute Exacerbation of Chronic Obstructive Pulmonary Disease (AECOPD)This episode of the SOS AMS podcast focuses on the diagnosis and management of AECOPD. Our hosts review how to identify which patients may benefit from antibiotics, and discuss appropriate antimicrobial agents for AECOPD. They finish the podcast by applying the principles discussed to a patient case, going from differential diagnosis to management. Check out the clinical decision-making matrix for a summary of our top 3 differential diagnoses, as well as the relevant references at the hyperlinks provided.    The learning objectives for this podcast are as follows: Describe the pathogenesis of AECOPD Distinguish bacterial AECOPD fr...2022-09-2524 minSOS AMS PodcastSOS AMS PodcastBugs and DrugsIn this next episode of the SOS AMS podcast, our hosts lay a foundation for future podcasts by outlining the most commonly encountered microbes in clinical practice, and the antibiotics used to treat them. They then apply this knowledge of microbiology and antibiotics by rationalizing the guideline-suggested antibiotic treatment of various different infections. Relevant references can always be accessed via the hyperlink.    The learning objectives for this episode are as follows: Recognize commensal flora of different physiologic regions of the human body.  Understand the link between the human microbiome and empiric antimicrobial selection. Describe som...2022-09-2519 minSOS AMS PodcastSOS AMS PodcastAMS General PrinciplesThe first episode of the SOS AMS podcast focuses on general clinical topics in AMS, such as discerning when a patient has improved clinically and is appropriate for stepdown to an oral antibiotic, and developing a differential diagnosis for perceived non-response to antibiotics. Our hosts Julia and Nicki explore key clinical features and patterns for distinguishing antibiotic failure from a source control issue or from a non-infectious mimicker of infection in patients who are not responding to antibiotics. The principles discussed are applied to two patient cases at the end of the podcast. Relevant references can always accessed through...2022-09-2520 min