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The Dr. Brighten ShowThe Dr. Brighten ShowMouth Breathing, ADHD & the Cavity Conspiracy: What Your Dentist Isn’t Telling You | Dr. Staci WhitmanIs your child’s ADHD, anxiety, or picky eating actually caused by mouth breathing? And what does fluoride in your water really do to your brain? In this eye-opening conversation, Dr. Staci Whitman—founder of NoPo Kids Dentistry and global leader in functional pediatric oral health—joins me to expose the hidden links between oral health, airway issues, the microbiome, and behavior.👉 Don’t forget to LIKE, COMMENT, and SUBSCRIBE for more expert-led conversations to help you take back your health.This episode is brought to you by: 2025-04-151h 33How to HealthHow to HealthHow to Prevent DementiaEvery three seconds someone in the world is diagnosed with dementia- a disease that leads to a decrease in mental function. There's currently no cure for dementia making prevention all the more important. In this episode we discuss what is dementia (and how it's not just a thing of ageing), what are the risk factors and how you do and eat affects your chances of getting (or not getting) dementia. Select references cited in this podcast: Association of daily step count and intensity with incident dementia in 78 430 adults living in the UK:  https://jamanetwork.com/j...2025-04-1456 minThis Week in CardiologyThis Week in CardiologyFeb 28 2025 This Week in CardiologyThe treatment of asymptomatic aortic stenosis, the move to composite endpoints in trials, IFR vs FFR and high-frequency low tidal volume ventilation for AF ablation are the topics John Mandrola, MD, discusses in today's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I Aortic valve intervention for Asymptomatic AS Lindman editorial https://jamanetwork.com/journals/jamacardiology/fullarticle/2829881 Trends https://pmc.ncbi.nlm.nih.gov/articles/PMC11308430/ Podcast EARLY TAVR Nov 8, 2024 This Week in Cardiology Podcast h...2025-02-2831 minStraight From The Cutter\'s Mouth: A Retina PodcastStraight From The Cutter's Mouth: A Retina PodcastEpisode 458: Journal Club Including GLP-1 Agonists and AMD, Distribution of US Ophthalmologists, Representation Quotients in Ophthalmology Residency, Photobiomodulation ViewpointDrs. Akshay Thomas and Sarwar Zahid join the podcast to discuss 4 recent articles in major ophthalmology journals.GLP-1 Agonists (https://www.aaojournal.org/article/S0161-6420(25)00070-3/fulltext)Distribution of US Ophthalmologists (https://jamanetwork.com/journals/jamaophthalmology/article-abstract/2828323)Representation Quotients in Ophthalmology Residency (https://jamanetwork.com/journals/jamaophthalmology/article-abstract/2828878)Photobiomodulation Viewpoint (https://jamanetwork.com/journals/jamaophthalmology/article-abstract/2829594)2025-02-2500 minUnder The ScrubsUnder The ScrubsOh Oh Oh OzempicSend us a textIn this episode, Hannah dives deep into Ozempic, Wegovy, and other GLP-1 receptor agonists, the groundbreaking medications transforming weight loss and type 2 diabetes management. We explore how GLP-1 drugs work, their benefits, side effects, and the latest research on their impact beyond diabetes—the good, the bad, and the ugly. We also look into the lawsuits that are being brought up and might threaten the future of the medication.Join us as we break down the science behind semaglutide and similar medications, discuss who might benefit from them, and explore alternative me...2025-02-1128 minThis Week in CardiologyThis Week in CardiologyJan 31 2025 This Week in CardiologyAnother negative AF ablation trial, predicting AF after stroke, the value of RCTs, troponin testing in the ED and surgical aortic valve choice are the topics John Mandrola, MD, discusses this week. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I AF ablation Coronary Sinus Isolation for High-Burden Atrial Fibrillation: A Randomized Clinical Trial https://doi.org/10.1016/j.jacep.2024.09.017 Approaches to Catheter Ablation for Persistent Atrial Fibrillation (STAR AFII) https://www.nejm.org/doi/full/10.1056/NEJMoa1408288 E...2025-01-3125 minThe Rural ImpactThe Rural Impact2025 & The Impact of Policy Shifts with Larry Levitt and Edwin ParkIn part one of the first episode of the new series 2025 & The Impact of Policy Shifts, Michelle sat down with Larry Levitt, Vice President for Health Policy at KFF. Levitt oversees policy work on Medicare, Medicaid, the health care marketplace, the Affordable Care Act, racial equity, women’s health, and global health. He previously was editor-in-chief of kaisernetwork.org, which was KFF’s online health policy news and information service and directed KFF’s communications. Prior to joining KFF, Levitt served as a senior health policy adviser to the White House and the Department of Health and Human Services, workin...2025-01-1645 minThis Week in CardiologyThis Week in CardiologyDec 20 2024 This Week in CardiologyListener feedback, multiple studies in AF ablation, a DANISH trial substudy of ICDs in NICM, and more data on eye complications of GLP-1 agonists are the topics John Mandrola, MD, covers in this week’s podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I. CCTA Feedback Foy meta-analysis https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2655243 DANCAVAS https://www.nejm.org/doi/full/10.1056/NEJMoa2208681 II. Listener Feedback on my negative take of the OPTION Tri...2024-12-2036 minThis Week in CardiologyThis Week in CardiologyDec 06 2024 This Week in CardiologyTirzepatide vs semaglutide in obesity; GLP1a use is complicated; HF outcomes; the misuse of meta-analyses in HF; and a breakthrough in HF care are the topics John Mandrola, MD, covers this week. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I. SURMOUNT 5 Clinicaltrials.gov https://clinicaltrials.gov/study/NCT05822830 Press Release   II. Access to GLP-1 Agonist Drugs CMS statement https://www.cms.gov/newsroom/press-releases/biden-harris-administration-announces-medicare-advantage-and-medicare-part-d-prescription-drug III. SUMMIT TRIAL commentary Ha...2024-12-0627 minThe Body of EvidenceThe Body of Evidence110 - Chelation Therapy for Heart DiseaseIt’s a pseudoscience that seemed to work at first, but now the same researcher who “proved” that it worked has proven that it doesn’t. Do we need to purge people of heavy metals to make sure they don’t have heart attacks? No… but you won’t believe the price tag we’ve had to pay to gain this wisdom.   Become a supporter of our show today either on Patreon or through PayPal! Thank you! http://www.patreon.com/thebodyofevidence/ https://www.paypal.com/donate?hosted_button_id=9QZET78JZWCZE  2024-09-2520 minThis Week in CardiologyThis Week in CardiologySep 20 2024 This Week in CardiologyListener feedback, K levels post cardiac surgery, cardiac device safety, disparities in preventive care, stopping trials early, and a SHAM-PVI update are the topics John Mandrola, MD, covers this week. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I. Listener Feedback Sep 13, 2024 This Week in Cardiology Podcast https://www.medscape.com/viewarticle/1001596 Sripal Bangalore Tweet on Yusef Meta-analysis https://x.com/SripalBangalore/status/1750116964893094125 II. Post Cardiac Surgery AF TIGHT K T...2024-09-2022 minThis Week in CardiologyThis Week in CardiologyAug 02 2024 This Week in CardiologyTwo downsides of PFA including autonomic tone and hemolysis, a bad surrogate in AF care, and controversies in defining cardiac risk are the topics John Mandrola, MD, covers in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I.PFA and Its (lack of) Effect on Autonomic Tone Pulsed Field Ablation for AF: Are US Electrophysiologists Too Easily Impressed? https://www.medscape.com/viewarticle/pulsed-field-ablation-af-are-us-electrophysiologists-too-2024a1000d2v Autonomic Tone P...2024-08-0228 minThis Week in CardiologyThis Week in CardiologyJul 26, 2024 This Week in Cardiology PodcastHealth and income, high BP in the hospital, and more on subclinical AF and when to use anticoagulants are the topics John Mandrola, MD, discusses in this week’s podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic   I. Health and Income  A Cash Giveaway to Improve Health https://www.medscape.com/viewarticle/cash-giveaway-improve-health-2024a1000dhf?form=fpf JAMA RCT https://jamanetwork.com/journals/jama/fullarticle/2821454 NBER RCT https://www.nber.org/paper...2024-07-2624 minThis Week in CardiologyThis Week in CardiologyJul 19 2024 This Week in CardiologyVulnerable plaque and scientific method; industry payments to trainees; tirzepatide or semaglutide; trial interpretation; and PFA are the topics John Mandrola, MD, covers in today’s podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I. Non-invasive Imaging for Vulnerable Plaque   PET Imaging Finds Vulnerable Plaques That Cause MI https://www.medscape.com/viewarticle/pet-imaging-finds-vulnerable-plaques-cause-mi-2024a1000cm2 JACC paper https://doi.org/10.1016/j.jacc.2024.03.419 Original JAMA-Card paper https://jamanetwork.com/journals/jama...2024-07-1925 minThis Week in CardiologyThis Week in CardiologyJul 12 2024 This Week in CardiologyVenous closure devices, GLP1-s linked to blindness and cancer, resisting the urge to do an ECG, and transcatheter edge-to-edge repair (TEER) for secondary mitral regurgitation are the topics discussed this week. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I Listener Feedback Venous vascular closure system vs. figure-of-eight suture following atrial fibrillation ablation: the STYLE-AF Study https://doi.org/10.1093/europace/euae105 II GLP1-s and Blindness Risk of Nonarteritic Anterior Ischemic Optic Neuropathy i...2024-07-1229 minThis Week in CardiologyThis Week in CardiologyJun 28 2024 This Week in CardiologyScreening echo, multivitamins, wasteful research, another PA sensor for HF, vascular closure devices, and GLP-1 marketing as science research are the topics John Mandrola, MD, discusses this week. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I. Screening for Valvular HD in the Elderly EHJ-CV Imaging Paper https://doi.org/10.1093/ehjci/jeae127 II. Vitamins and Wasteful Research Is Red Meat Healthy? Multiverse Analysis Has Lessons Beyond Meat   https:// www.medscape.com/viewarticle/red-meat-healthy-multiverse-analysis-has-lessons-beyond-meat-2024a10...2024-06-2825 minTrending with TimmerieTrending with TimmerieMedical Data on Birth Control & Chemical AbortionThe latest medical data on birth control – ingredient progestin causes cancer. Pam Stenzel, the Client Services Director for 5 pregnancy resource centers, joins Trending with Timmerie. (6:05) What’s the most common type of abortion?  How are women harmed by chemical abortion? (6:48) Dating trends and women falling in love with AI boyfriends. One woman’s engagement ended because of her AI affair.    Resources mentioned:  Birth control over the counterhttps://relevantradio.com/2024/03/loud-budgeting-ditching-the-pill/ Contraception studies: 2023 UK Study: Fitzpatrick D, Pirie K, Reeves G, Green J, Beral V (2023) Combined and progestagen-only hormonal contraceptives and breast cancer risk: A UK nested case–contro...2024-05-1750 minTrending with Timmerie - Catholic Principles applied to today\'s experiences.Trending with Timmerie - Catholic Principles applied to today's experiences.Medical Data on Birth Control & Chemical AbortionThe latest medical data on birth control – ingredient progestin causes cancer. Pam Stenzel, the Client Services Director for 5 pregnancy resource centers, joins Trending with Timmerie. (6:05) What’s the most common type of abortion?  How are women harmed by chemical abortion? (6:48) Dating trends and women falling in love with AI boyfriends. One woman’s engagement ended because of her AI affair.    Resources mentioned:  Birth control over the counterhttps://relevantradio.com/2024/03/loud-budgeting-ditching-the-pill/ Contraception studies: 2023 UK Study: Fitzpatrick D, Pirie K, Reeves G, Green J, Beral V (2023) Combined and progestagen-only hormonal co...2024-05-1750 minThis Week in CardiologyThis Week in CardiologyApr 19 2024 This Week in CardiologyACC Part 2: The TACT2 trial of chelation, inter-atrial shunts for HF, and triglyceride lowering; plus diltiazem and Factor Xa anticoagulants are the topics John Mandrola, MD, covers this week. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I. TACT 2 Chelation Therapy Provides No Benefit Post-MI https://www.medscape.com/viewarticle/chelation-therapy-provides-no-benefit-post-mi-2024a10006l5 Chelation Therapy and CV Risk: Why TACT2 Showed No Benefit https://www.medscape.com/viewarticle/chelation-therapy-and-cv-risk-why-tact2-showed-no-benefit-2024a1000761?s...2024-04-1928 minThis Week in CardiologyThis Week in CardiologyMar 29, 2024 This Week in Cardiology PodcastIntermittent fasting, anticoagulation decisions, heterogenous treatment effects, frailty in HF, the importance of the ECG, and industry conflicts are the topics John Mandrola, MD, covers this week. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I. Intermittent Fasting No, Intermittent Fasting Won't Kill You https://www.medscape.com/viewarticle/1000544 NEJM Paper on Time-Restricted Eating  https://www.nejm.org/doi/full/10.1056/NEJMoa2114833 JAMA TREAT Clinical Trial https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2771095 II. Stroke Pr...2024-03-2928 minThis Week in CardiologyThis Week in CardiologyFeb 09 2024 This Week in CardiologyBeta-blocker withdrawal in HFpEF, the ARCADIA trial, food as medicine, and bariatric surgery are the topics John Mandrola, MD, discusses in today’s podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I. HFpEF and Heart Rate PRESERVE HF Substudy https://jamanetwork.com/journals/jamacardiology/fullarticle/2814596 PRESERVE HF Original https://doi.org/10.1016/j.jacc.2021.08.073 II. ARCADIA trial ARCADIA Main Paper: Apixaban vs ASA https://jamanetwork.com/journals/jama/fullarticle/2814933 KAMEL’s AF and Stroke Paper...2024-02-0925 minStraight From The Cutter\'s Mouth: A Retina PodcastStraight From The Cutter's Mouth: A Retina PodcastEpisode 414: Journal Club on Real-World Results of Faricimab, AI Prediction for Dry AMD, Risk of Stroke/MI after Retinal Arteriole Occlusion, Climate ChangeDrs. Akshay Thomas, Priya Vakharia, and Sarwar Zahid join for a journal club discussion of four recent articles in major ophthalmology journals.Real-World Faricimab Results (https://www.ophthalmologyretina.org/article/S2468-6530(23)00569-9/fulltext)Artificial Intelligence for Dry AMD (https://jamanetwork.com/journals/jamaophthalmology/fullarticle/2810428)Risk of Stroke/MI after RAO (https://jamanetwork.com/journals/jamaophthalmology/article-abstract/2810736)Climate Change Crisis (https://jamanetwork.com/journals/jamaophthalmology/fullarticle/2811163)2023-12-0800 minThis Week in CardiologyThis Week in CardiologyOct 06 2023 This Week in CardiologyCoated vs uncoated ASA, a new trial in CAD, conflicts of interest, first AF in the hospital, and changing HTN scoring and CHADSVASC are the topics John Mandrola, MD, covers in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I. ASA No Benefit of Enteric-Coated Aspirin vs Uncoated in CVD https://www.medscape.com/viewarticle/997119 -  JAMA Cardiology: Coated vs Uncoated ASA https://jamanetwork.com/journals/jamacardiology/fullarticle/2809795 -  ...2023-10-0623 minThe Body of EvidenceThe Body of Evidence095 - Macular Degeneration / Fall Vaccines / Blue-Blocking GlassesWhat does the body of evidence say on age-related macular degeneration (AMD) and how to treat the #1 cause of blindness in North America? Plus: which vaccines are available this fall to prevent respiratory tract infections, and a look at whether blue-light-blocking glasses will make a difference in your life! Block 1: (2:15) AMD: how common it is, what happens in the eye, risk factors Block 2: (9:20) AMD: dry AMD versus wet AMD, how to diagnose it, how to prevent it, AREDS supplements, VEGF inhibitors, lasers, rehabilitation Block 3: (25:54) Fall vaccines: COVID...2023-10-031h 01This Week in CardiologyThis Week in CardiologyAug 11, 2023 This Week in Cardiology PodcastObservational studies, another defense of digoxin, CTO-PCI, BP measurement, and a possible revolution in cardiovascular protection are the topics John Mandrola, MD, discusses in this week’s podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I. Observational Research Yeh; Credibility in Observational  Research https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.123.064645 Hernan; Causal Language in Observational Research  https://ajph.aphapublications.org/doi/full/10.2105/AJPH.2018.304337 Wang; RCT Duplicate Initiative https://jamanetwork.com/journals/jama/fullarticle/2804067 2023-08-1129 minThis Week in CardiologyThis Week in CardiologyJul 7 2023 This Week in CardiologyEuropean HTN Guidelines, vitamin D, bempedoic acid, and leadless pacing, with some critical appraisal techniques thrown in, are the topics John Mandrola, MD, tackles in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I. European Hypertension Guidelines New ESH Hypertension Guidelines Aim for Simplified Message https://www.medscape.com/viewarticle/993913 - 2023 ESH Guidelines for the management of arterial hypertension The Task Force for the management of arterial hypertension o...2023-07-0727 minThis Week in CardiologyThis Week in CardiologyJune 9 This Week in CardiologyImpella, digital health, low-value processes, are tricuspid valve interventions with pacing leads are the topics Dr. John Mandrola, MD, discusses in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I. Impella Class I Recall FDA Class I Recall for Some Abiomed Impella Heart Pumps https://www.medscape.com/viewarticle/992845 - A Prospective, Randomized Clinical Trial of Hemodynamic Support With Impella 2.5 Versus Intra-Aortic Balloon Pump in Patients Undergoing High-Risk P...2023-06-0929 min凱熙陪你吃早餐凱熙陪你吃早餐EP.090 孩子使用3C產品可能增加自閉症風險!?1歲時看螢幕的時間越長,3歲時得到自閉症的風險越高? 3C產品對兒童健康的危害:家長應該注意什麼? 兒童使用3C產品:父母如何控制使用時間保護孩子健康? 明天有特別節目唷,要準時收聽起來 🔥有神秘嘉賓來分享推薦!!🔥 參考文獻: https://jamanetwork.com/journals/jamapediatrics/fullarticle/2788488 https://jamanetwork.com/journals/jamapediatrics/article-abstract/2792666 https://jamanetwork.com/journals/jamapediatrics/article-abstract/2792665 🍎每天10分鐘,健康在這邊 🍎 👉好食 · 好時 粉絲團:https://www.facebook.com/howjiacathy 👉來信解決健康疑難雜症:howjiacathy@gmail.com 👉更多優質課程:https://linktr.ee/healthcare_consultant -- Hosting provided by SoundOn 2023-05-0420 minFierce Fatty PodcastFierce Fatty Podcast165: “Weight Loss” Surgery Stats and Stories (part 3)Does weight loss surgery make you thin? What percentage of people is it successful for? Are the side effects worth it and what are they exactly? This episode is a deep dive into bariatric surgery AKA "weight loss" surgery AKA stomach amputation. CW: There are mentions of the O Words, suicide rates and brief mention of calories. Episode show notes: http://www.fiercefatty.com/165 Support me on Ko-Fi and get the Size Diversity Resource Guide: https://ko-fi.com/fiercefatty/tiers Comparison of the Performance of Common Measures of Weight Regain After Bariatric Surgery...2023-05-021h 15This Week in CardiologyThis Week in CardiologyApr 28 2023 This Week in CardiologyTwo studies of cardiac device infections, observational studies, RCTs, and our ways of knowing in Medicine are the topics discussed by John Mandrola, MD in this week’s podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I. Cardiac Device Infection Mortality Climbs When CIED Infections Are 'Delayed' After Implant https://www.medscape.com/viewarticle/990692 - Association of the Timing and Extent of Cardiac Implantable Electronic Device Infections With Mortality https://jam...2023-04-2829 minBMJ talk medicineBMJ talk medicineADC Fetal and Neonatal’s Fantoms. Highlights from the March 2023 issueADC Fetal and Neonatal’s Associate Editor, Jonathan Davis, and the Edition Editor of the journal, Ben Stenson, discuss the highlights from the March 2023 issue. The Fantoms article: https://fn.bmj.com/content/108/2/95 Additional links: Caffeine Therapy for Apnea of Prematurity https://www.nejm.org/doi/full/10.1056/nejmoa054065 Survival Without Disability to Age 5 Years After Neonatal Caffeine Therapy for Apnea of Prematurity https://jamanetwork.com/journals/jama/fullarticle/1104870 Survival Without Disability to Age 5 Years After Neonatal Caffeine Therapy for Apnea of Prematurity https://jamanetwork.com/journals/jama/fullarticle/1104865 Academic Performance, Motor Function, and Behavior 11 Years After Neonatal Caffeine Citrate Therapy fo...2023-04-1122 minADC podcastADC podcastADC Fetal and Neonatal’s Fantoms. Highlights from the March 2023 issueADC Fetal and Neonatal’s Associate Editor, Jonathan Davis, and the Edition Editor of the journal, Ben Stenson, discuss the highlights from the March 2023 issue. The Fantoms article: https://fn.bmj.com/content/108/2/95 Additional links: Caffeine Therapy for Apnea of Prematurity https://www.nejm.org/doi/full/10.1056/nejmoa054065 Survival Without Disability to Age 5 Years After Neonatal Caffeine Therapy for Apnea of Prematurity https://jamanetwork.com/journals/jama/fullarticle/1104870 Survival Without Disability to Age 5 Years After Neonatal Caffeine Therapy for Apnea of Prematurity https://jamanetwork.com/journals/jama/fullarticle/1104865 Academic Performance, Motor Function, and Behavior 11 Years After Neonatal Caffeine Citrate Therapy fo...2023-04-1122 minADC PodcastADC PodcastADC Fetal and Neonatal’s Fantoms. Highlights from the March 2023 issueADC Fetal and Neonatal’s Associate Editor, Jonathan Davis, and the Edition Editor of the journal, Ben Stenson, discuss the highlights from the March 2023 issue. The Fantoms article: https://fn.bmj.com/content/108/2/95 Additional links: Caffeine Therapy for Apnea of Prematurity https://www.nejm.org/doi/full/10.1056/nejmoa054065 Survival Without Disability to Age 5 Years After Neonatal Caffeine Therapy for Apnea of Prematurity https://jamanetwork.com/journals/jama/fullarticle/1104870 Survival Without Disability to Age 5 Years After Neonatal Caffeine Therapy for Apnea of Prematurity https://jamanetwork.com/journals/jama/fullarticle/1104865 Academic Performance, Motor Function, and Behavior 11 Years After Neonatal Caffeine Citrate Therapy fo...2023-04-1122 minThis Week in CardiologyThis Week in CardiologyMar 31 2023 This Week in CardiologyDiets, coronary artery calcium, statins, basic CAD knowledge, and AF ablation are the topics John Mandrola, MD, discusses in this week’s podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I. Diet Some Diets Better Than Others for Heart Protection https://www.medscape.com/viewarticle/990305 - Comparison of seven popular structured dietary programmes and risk of mortality and major cardiovascular events in patients at increased cardiovascular risk: systematic review and network meta-analysis https://doi.org...2023-03-3127 minThis Week in CardiologyThis Week in CardiologyMar 17 2023 This Week in CardiologyACC Recap No. 2: Pacing in HFpEF, Oral PCSK9 inhibitor, PAH, soft thinking on adherence, and so called metabolically healthy obese are discussed by John Mandrola, MD, in this week’s podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I. Pacing in HFpEF No Exercise Boost From Pacemaker in HFpEF With Impaired HR Response: RAPID-HF https://www.medscape.com/viewarticle/989681 - Rate-Adaptive Atrial Pacing for Heart Failure With Preserved Ejection FractionThe RAPID-HF Randomized Clinical Trial htt...2023-03-1729 minThis Week in CardiologyThis Week in CardiologyMar 3 2023 This Week in CardiologyRenal denervation, AF ablation, omecamtiv mecarbil, and an ACC Preview are the topics discussed by John Mandrola, MD, in this week’s podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I. AF Ablation - Initial Findings From the National Cardiovascular Data Registry of Atrial Fibrillation Ablation Procedures https://www.jacc.org/doi/10.1016/j.jacc.2022.11.060 II. Renal Denervation Consistent BP Cut With Renal Denervation: More on RADIANCE https://www.medscape.com/viewarticle/989006 ...2023-03-0324 min5-Minute Clinical Update and Grand Rounds with Dr. Thomas McGinn5-Minute Clinical Update and Grand Rounds with Dr. Thomas McGinn5-Minute Check in: Rev. Dr. MLK Jr., Quadrademic, Upcoming Episode TopicsCommemorating Rev. Dr. Martin Luther King, Jr. DayQuadrademicPreview of Upcoming Episode TopicsObesity: https://publications.aap.org/pediatrics/article/doi/10.1542/peds.2022-060640/190443/Clinical-Practice-Guideline-for-the-Evaluation-and?autologincheck=redirected Nudges: https://jamanetwork.com/journals/jamacardiology/fullarticle/2798971 Paxlovid: https://drive.google.com/file/d/15se0l3Nk09JI3LPJCaM9yqYX0ceTkjtX/view?usp=share_link Colonoscopy: https://jamanetwork.com/journals/jama/fullarticle/2798744Readmissions: https://jamanetwork.com/journals/jama/fullarticle/2797277Podcast Recommendation: https://podcasts.apple.com/us/podcast/kelly-corrigan-wonders/id1532951390?i=10005928321142023-01-1604 minThis Week in CardiologyThis Week in CardiologyDec 16, 2022 This Week in Cardiology PodcastBP control over the long term, omecamtiv mecarbil, incentives and Goodhart’s law, and open science are the topics John Mandrola, MD, covers in this week’s podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I. Long-Term BP Control - Final SPRINT Data Confirm Lower BP Is Better https://www.medscape.com/viewarticle/951572 - Longer-Term All-Cause and Cardiovascular Mortality With Intensive Blood Pressure Control https://jamanetwork.com/journals/jamacardiology/fullarticle/2797064 - Let's Not SPRINT to Judgment Abou...2022-12-1627 minThis Week in CardiologyThis Week in CardiologyDec 9, 2022 This Week in Cardiology PodcastNudges, statins, AI, less-is-more in the ICU, myocarditis, exercise as medicine, and December in the hospital are the topics John Mandrola, MD, covers in this week’s podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I. Nudges and Statin Prescribing EHR Alerts to Both Doc and Patient May Boost Statin Prescribing https://www.medscape.com/viewarticle/984944 Effect of Nudges to Clinicians, Patients, or Both to Increase Statin Prescribing https://jamanetwork.com...2022-12-0922 minThis Week in CardiologyThis Week in CardiologyNov 4, 2022 This Week in Cardiology PodcastAF conversion in the ED, HRT, a shining example of evidence-based medicine and less-is-more, multimorbidity, and what’s coming at AHA are the topics John Mandrola, MD, covers in this week’s podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I. AF Conversion - IV Potassium and Magnesium an Acute Treatment for AF? https://www.medscape.com/viewarticle/983137 - Association of Intravenous Potassium and Magnesium Administration With Spontaneous Conversion of Atrial Fibrillation and Atrial Flutter in the Emergency Depa...2022-11-0421 minThis Week in CardiologyThis Week in CardiologyOct 21, 2022 This Week in Cardiology PodcastThe ERASE AF ablation trial, left bundle pacing, finerenone, and perceptions of cardiology are the topics John Mandrola, MD, discusses in this week’s podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I. AF Ablation - Low-Voltage Myocardium-Guided Ablation Trial of Persistent Atrial Fibrillation https://evidence.nejm.org/doi/10.1056/EVIDoa2200141 - Approaches to Catheter Ablation for Persistent Atrial Fibrillation https://www.nejm.org/doi/full/10.1056/NEJMoa1408288 - Effect of MRI-Guided Fibrosis Ablation vs Conventional Catheter Ablation on...2022-10-2126 minThis Week in CardiologyThis Week in CardiologyOct 7, 2022 This Week in CardiologyPost-PCI antiplatelet therapy, palliative care in patients with HF, Watchman information on hospital websites, and HCM in athletes are the topics John Mandrola, MD, covers in this week’s podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I. Post-Stent Antiplatelet Therapy SMART-CHOICE 3-Year Results Support Dropping Aspirin After PCI https://www.medscape.com/viewarticle/981741 Long-term Effects of P2Y12 Inhibitor Monotherapy After Percutaneous Coronary Intervention https://jamanetwork.com/journals/jamacardiology/fullarticle/2796902 The Smart(est...2022-10-0722 minThis Week in CardiologyThis Week in CardiologyAug 19, 2022 This Week in Cardiology PodcastThe obesity paradox in AF and paradoxes in general, digital health gets whacked again, and direct-to-consumer ads are the topics discussed by John Mandrola, MD in this week’s podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I. Collider Bias and the Obesity Paradox - 'Obesity Paradox' in Atrial Fibrillation Challenged as Mortality Climbs With BMI https://www.medscape.com/viewarticle/979150 - Association of body mass index with outcomes in patients with newly diagnosed atrial fibrillation: GARFIELD-AF https://ope...2022-08-1922 minThis Week in CardiologyThis Week in CardiologyJuly 29, 2022 This Week in CardiologyA big new HF and EP trial, doctors and probability, LV assist devices in cardiogenic shock, vitamin D, and exercise in PAD are the topics John Mandrola, MD, discusses in this week’s podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I. Left vs Left RCT Taking Cardiac Pacing From Boring to Super-Cool https://www.medscape.com/viewarticle/973615 Conduction-System Pacing Shines vs BiV Pacing for CRT in Early Studies https://www.medscape.com...2022-07-2923 minThis Week in CardiologyThis Week in CardiologyJul 8, 2022 This Week in Cardiology PodcastOn this week’s podcast, John Mandrola, MD discusses fish oil, America’s heart health, pharmacists and prescribing and statins This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I - Fish Oil - New Biomarker Data Add to Concerns Over REDUCE-IT Trial https://www.medscape.com/viewarticle/976490 - Effects of Randomized Treatment With Icosapent Ethyl and a Mineral Oil Comparator on Interleukin-1β, Interleukin-6, C-Reactive Protein, Oxidized Low-Density Lipoprotein Cholesterol, Homocysteine, Lipoprotein(a), and Lipoprotein-Associated Phospholipase A2: A REDUCE-IT Biomarker Subst...2022-07-0823 minThis Week in CardiologyThis Week in CardiologyJune 24, 2022 This Week in CardiologyA non-significant but wonderful trial in AF, smoking and HF, vitamins, and pre-op risk screening are the topics discussed by John Mandrola, MD, in this week’s podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I – DECAAF II Trial DECAAF II: AF, Fibrosis Ablation Technique Falls Short, but Signs of Hope https://www.medscape.com/viewarticle/957469 • Effect of MRI-Guided Fibrosis Ablation vs Conventional Catheter Ablation on Atrial Arrhythmia Recurrence in Patient...2022-06-2420 min\'ne Dosis Wissen | Der Medizin-Podcast für Menschen im Gesundheitswesen'ne Dosis Wissen | Der Medizin-Podcast für Menschen im GesundheitswesenAspirin zur Prävention kardiovaskulärer ErkrankungenASS-Prophylaxe nur jüngere Patient:innen geben – nach Risikoabschätzung Die Vision war wunderbar: Täglich zum Frühstück eine kleine Dosis Aspirin nehmen – und gut geschützt sein vor Herzinfarkt und Schlaganfall. Doch der Traum ist inzwischen dermaßen geplatzt, dass die ASS-Prophylaxe ausschließlich für einige jüngere Patient:innen empfohlen wird. Dr. Laura Weisenburger, Ärztin und wissenschaftliche Redakteurin der Apotheken Umschau, erläutert, warum und wieso. Quellen und nützliche Links https://jamanetwork.com/journals/jama/fullarticle/2791399 https://leitlinien.dgk.org/files/03_2016_pocket_leitlinien_praevention.pdf https://jamanetwo...2022-05-1811 minStraight From The Cutter\'s Mouth: A Retina PodcastStraight From The Cutter's Mouth: A Retina PodcastEpisode 343: Journal Club including discussion of fibrates for DR, natural history of ERM, COVID-19 and vascular occlusions, Google searches and TeprotumumabDrs. Nicholas Farber, M. Ali Khan, and Safa Rahmani join for a journal club discussion of four recent publications in major ophthalmology journals:Fibrates and Diabetic Retinopathy (https://jamanetwork.com/journals/jamaophthalmology/article-abstract/2790668)Natural History of Epiretinal Membranes (https://www.ophthalmologyretina.org/article/S2468-6530(22)00087-2/fulltext#%20)COVID-19 and Vascular Occlusions (https://jamanetwork.com/journals/jamaophthalmology/fullarticle/2790988)Google Searches for Thyroid Eye Disease and Teprotumumab (https://jamanetwork.com/journals/jamaophthalmology/article-abstract/2791596)Financial Disclosures: Dr. Sridhar is a consultant for Alcon, Allergan, Dorc, Genentech, and Regeneron. Dr. Khan, Dr. Farber...2022-05-1600 minHouse of MedicineHouse of MedicineBasics of ARDSThis episode Brian, Awais, and Adnan welcome their co-resident Mo to the podcast to discuss the basics of ARDS and mechanical ventilation in these patients. As always, there are a lot of laughs and quite a bit of banter. We mention several trials during our discussion that are linked below (show notes).ARDSNet/ARMA trialhttps://www.nejm.org/doi/full/10.1056/NEJM200005043421801ARDSNet/ALVEOLI trialhttps://www.nejm.org/doi/full/10.1056/NEJMoa032193EXPRESS trialhttps://jamanetwork.com/journals/jama/fullarticle/181426LOVS trialhttps://jamanetwork.com/journals/jama...2022-04-0340 min\'ne Dosis Wissen | Der Medizin-Podcast für Menschen im Gesundheitswesen'ne Dosis Wissen | Der Medizin-Podcast für Menschen im GesundheitswesenWas bringt Deprescribing bei älteren Menschen?Bislang kaum Nutzen von Deprescribing nachgewiesen Multimorbide Menschen bekommen viele Medikamente verschrieben, darunter auch unangemessene. Doch ist weniger vielleicht mehr? Dennis Ballwieser, Arzt und Chefredakteur der Apotheken Umschau, klärt darüber auf, was das Deprescribing bei älteren Patienten bringt. Quellen und nützliche Links: Cluster-randomisierte Studie zu Auswirkungen eines Medikamentenchecks in BMJ: https://www.bmj.com/content/374/bmj.n1585.full Schwedische Studie zu Auswirkungen eines Medikamentenchecks in JAMA Network Open: https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2779378?utm_campaign=articlePDF&utm_medium=articlePDFlink&utm_source=articlePDF&utm_content=jamanetworkopen.2021.6392 US-Amerikanische Studie zu d...2022-03-0810 minQuestioning MedicineQuestioning MedicineMedical Update 191- Afib and coffee, elective ortho and PRP, Antibiotic overuse, low back painhttps://jamanetwork.com/journals/jamainternalmedicine/article-abstract/2782015coffee is ok with atrial fibrillation -- just don't go crazy is probably good advicehttps://jamanetwork.com/journals/jamanetworkopen/fullarticle/2781351Hearing loss sucks and can really change your whole physical functionhttps://www.bmj.com/content/374/bmj.n1511elective orthopedic procedures with good evidence are limitedhttps://jamanetwork.com/journals/jama/fullarticle/2781859PRP injections -- work about as well as vitamin D-- just stophttps://www.bmj.com/content/374/bmj.n1446muscle relaxants for...2022-02-2523 minQuestioning MedicineQuestioning MedicineMedical Update 188 (KDIGO, pseudoanemia, Coronary calcium score, cardiogenic shock, UTI)https://pubmed.ncbi.nlm.nih.gov/33734980/if you lay flat with a blood draw you may have psuedoanemiahttps://jamanetwork.com/journals/jama/fullarticle/2782300Men and UTI-- 7 dayshttps://jamanetwork.com/journals/jamainternalmedicine/article-abstract/2782461don't get a UA prior to a procedure for screeninghttps://www.nejm.org/doi/full/10.1056/NEJMoa2026845cardiogenic shock- dobutamine vs milrinone https://pubmed.ncbi.nlm.nih.gov/34259820/Dont use a CAChttps://pubmed.ncbi.nlm.nih.gov/33637192/CKD = SBP 2022-01-1421 minDoctor Vs ComedianDoctor Vs ComedianEpisode 28: Life on the Road / Pharma influence on DoctorsThe guys start with a serious debate about whether ‘drums’ or ‘flats’ are the better chicken wings (00:50). Ali then discusses life on the road as a comedian (5:11), including tips on how to get started in comedy touring. Then, Asif discusses the influence of the pharmaceutical industry on the prescribing habits of doctors (29:36). He discusses his own personal experiences with pharma, as well as what the evidence says about whether the pens, dinners and trips given to doctors actually influences behaviour (spoiler: it does).  The opinions expressed are those of the hosts, and do not reflect those of a...2021-09-101h 00The IncubatorThe Incubator#019 - Journal Club - Do we even need car seat tests?, COVID19: Pregnancy/Neonatal outcomes, Breast milk and cardiac function at 1yr, Noise level inside incubators... and more!Send us a textAs always, feel free to send us questions, comments or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through instagram or twitter, @nicupodcast. Or contact Ben and Daphna directly via their twitter profiles: @drnicu and @doctordaphnamd. Papers discussed in today's episode are listed and timestamped below.enjoy!______________________________________________________________________________________________________Please find the list of articles discussed in this week’s journal club with links to the full text.03:15 - Characteristics and Outcomes of Women With COVID-19 Giving Birth at US...2021-09-051h 09Straight From The Cutter\'s Mouth: A Retina PodcastStraight From The Cutter's Mouth: A Retina PodcastEpisode 295: Journal Club Including Protocol W Discussion, Post-Hoc CLARITY Analysis, and moreProtocol W (https://jamanetwork.com/journals/jamaophthalmology/fullarticle/2778074) Post-Hoc Analysis of CLARITY (https://jamanetwork.com/journals/jamaophthalmology/fullarticle/2777497?resultClick=1) Racial and Socioeconomic Differences in DME Treatment (https://www.aaojournal.org/article/S0161-6420(21)00196-2/abstract) Anti-VEGF for Wet AMD Prophylaxis (https://jamanetwork.com/journals/jamaophthalmology/fullarticle/2777577?resultClick=1)2021-05-2449 minQuestioning MedicineQuestioning MedicineWeekly Update 176Compression stocking to prevent cellulitis? NOT SO FAST! Vitamin D still doesn't work even for depression. Hip fractures are on teh decline and it is not because of drugs. A scribe cost money, but how much? What about doing an LP with anticoagulants, it is probably safer than you think. What do you do with kidney stones? Finally, there is a lot of medical waste, so stop ordering MRIs for low back pain! https://pubmed.ncbi.nlm.nih.gov/33058700/https://pubmed.ncbi.nlm.nih.gov/32989711/https://www.auajournals.org/doi/10.1097/JU.0000000000001318https...2021-04-2023 minVideo Vault 3Video Vault 3Coronavirus Critical Care Update - January 2021The COVID-19 pandemic has prompted scientists to use adaptive research designs to evaluate potential treatments simultaneously and efficiently, increasing the likelihood that patients will receive treatments most likely to be effective for them. Lennie Derde, MD of @UMC Utrecht and Chris Seymour, MD of @UPMC join JAMA's Q&A series to discuss the latest in critical care management of COVID-19 patients and emerging treatment strategies and therapies. Originally broadcast January 13, 2021 • Earn Free CME credits by watching JAMA Livestreams and completing a brief questionnaire. Claim 0.5 credits for each video at https://ja.ma/covidqa • Coronavirus Reso...2021-04-0500 minVideo Vault 3Video Vault 3Coronavirus and Health InequitiesLinda Rae Murray, MD, MPH discusses topics in health equity with JAMA Medical News Associate Managing Editor Jennifer Abbasi. Recorded on June 19, 2020. • Earn Free CME credits by watching JAMA Livestreams and completing a brief questionnaire. Claim 0.5 credits for each video at https://ja.ma/covidqa • Coronavirus Resource page from the JAMA Network: https://ja.ma/covidyt ===================================================================== To watch all the #JAMALive Q&A's Visit: https://ja.ma/covidqaytpl Don't forget to hit subscribe or click https://ja.ma/subscribe #JAMALive #Coronavirus #SARSCoV2 For more from JAMA • https://www.ja...2021-04-0500 minVideo Vault 3Video Vault 3Coronavirus Vaccines - An IntroductionLeading COVID-19 vaccine candidates rely on new technologies that have fast-tracked development and testing. Vaccines from Pfizer and Moderna have completed early phase 3 clinical trials and are reportedly under review at the US FDA for emergency use authorization (EUA) although safety surveillance continues. This video explains the principles underlying the leading DNA, messenger RNA (mRNA), and viral vector vaccine candidates, and how they might induce immunity to SARS-CoV-2 infection. 0:00 Introduction 1:21 Traditional vaccines 2:00 COVID-19 vaccine types in development 2:18 Making vaccines from a genetic sequence 2:45 Target antigen: the S protein 3:32 Genetic vaccines (DNA and...2021-04-0500 minVideo Vault 3Video Vault 3Coronavirus Update With Carlos del Rio and Preeti MalaniCoronavirus trends, variants, vaccines, treatment, and more. @Michigan Medicine's Preeti Malani, MD and @Emory Healthcare's Carlos del Rio, MD return to JAMA's Q&A series to discuss the latest in COVID-19 medicine and public health. Recorded March 15, 2021. Read their COVID-19 in 2021—Continuing Uncertainty, at https://ja.ma/30G0UHA 0:00 Introductions 1:21 Lessons learned after 1 year of the pandemic 5:05 Vaccine choices: recommendations 7:04 Efficacy vs effectiveness 7:50 Variants: is there new information? 9:53 Do vaccines protect against infection and prevent transmission? 11:56 AstraZeneca/Oxford vaccine updates 13:29 New vaccine hesitancy 15:10 3ft vs 6ft: distance an...2021-04-0500 minVideo Vault 3Video Vault 3Coronavirus VariantsGenetic variants of the SARS-CoV-2 virus are emerging, but so far do not seem to have caused breakthrough infections in people with previous infection or in those who've been vaccinated. John P. Moore, PhD, of @Weill Cornell Medicine in New York, joins JAMA's Q&A series for an update on the latest variants and what you need to know. Recorded March 4, 2021. Read his SARS-CoV-2 Vaccines and the Growing Threat of Viral Variants at https://ja.ma/3q05WsR Topics discussed in this interview: 0:00 Introduction 0:36 Emerging variants 2:01 Rapidity of emergence 3:26 Effect of...2021-04-0500 minVideo Vault 3Video Vault 3Coronavirus Update With Carlos del Rio and Preeti MalaniCoronavirus trends, variants, vaccines, treatment, and more. @Michigan Medicine's Preeti Malani, MD and @Emory Healthcare's Carlos del Rio, MD return to JAMA's Q&A series to discuss the latest in COVID-19 medicine and public health. Recorded March 15, 2021. Read their COVID-19 in 2021—Continuing Uncertainty, at https://ja.ma/30G0UHA 0:00 Introductions 1:21 Lessons learned after 1 year of the pandemic 5:05 Vaccine choices: recommendations 7:04 Efficacy vs effectiveness 7:50 Variants: is there new information? 9:53 Do vaccines protect against infection and prevent transmission? 11:56 AstraZeneca/Oxford vaccine updates 13:29 New vaccine hesitancy 15:10 3ft vs 6ft: distance an...2021-04-0500 minThis Week in CardiologyThis Week in CardiologyMar 26, 2021 This Week in Cardiology PodcastCOVID-19, AF detection post stroke, new measures of heart function, and structural racism in quality measures are the topics covered by John Mandrola, MD, in this week’s podcast. https://www.medscape.com/twic COVID-19 NIH Rebukes AstraZeneca Vaccine Interim Data: 'Incomplete' https://www.medscape.com/viewarticle/947954 Neutralizing Antibodies Against SARS-CoV-2 Variants After Infection and Vaccination https://jamanetwork.com/journals/jama/fullarticle/2777898 AF and Stroke Insertable Cardiac Monitors Improve AF Detection After Stroke https://www.medscape.com/viewarticle/947986 Perfection in LV Function Measurement Adding Strain Me...2021-03-2619 minIn Bad TasteIn Bad TasteThe Magic Pill 01: Nothing magic about ketoHello wonderful listeners! We’re back and we’re not wasting any time getting to the bottom of Pete Evans’ ‘The Magic Pill’. This week, the ketogenic diet - is it as magical as this film wants you to believe?We had some technology drama while recording this, so please forgive us for not having quite the same high standard of audio that we usually do today.Follow Pixie Turner @pixienutrition on Instagram | Twitter | FacebookFollow Dr Nikki Stamp @drnikkistamp on Instagram | Twitter | FacebookEmail us with yo...2021-03-0936 minPetri DishPetri DishEp. 62 Bleedin' Gums and Vitamin CWe all know *about* vitamin C but... what actually IS vitamin C? And what does it even do in your body? How can being deficient in vitamin C make pirates bleed out of their gums and have their teeth fall out? Also, can vitamin C cure cancer? Find out some of this stuff, tune in! This episode is sponsored in part by Vaer Watches, which you can visit at  https://www.vaerwatches.com/. Currently you can get 15% off with the code PODGO15, check it out! This episode has a promo for Bald Scientist Podcast! This g...2020-09-141h 08Covid-19 update: Self-isolation, non-Covid-19 hospital admissions, planned care, and weightKieran Walsh, clinical director at BMJ, asks editors from BMJ Learning and BMJ Best Practice to summarise the latest clinical guidance related to covid-19. Matt Castleden updates us on self-isolation and shielding, and resources for people recovering from Covid-19. Abigail Davis discusses new evidence on the impact of Covid-19 on emergency department attendances and hospital admissions, as well as new guidance on planned care. And Emma Scott covers the link between weight and Covid-19. For more, see: BMJ Best Practice's topic on management of coexisting conditions in the context of COVID-19: bestpractice.bmj.com/topics/en-gb/3000190 BMJ Best Practice's topic...2020-08-1712 minCovid-19 update: Self-isolation, non-Covid-19 hospital admissions, planned care, and weightKieran Walsh, clinical director at BMJ, asks editors from BMJ Learning and BMJ Best Practice to summarise the latest clinical guidance related to covid-19. Matt Castleden updates us on self-isolation and shielding, and resources for people recovering from Covid-19. Abigail Davis discusses new evidence on the impact of Covid-19 on emergency department attendances and hospital admissions, as well as new guidance on planned care. And Emma Scott covers the link between weight and Covid-19. For more, see: BMJ Best Practice's topic on management of coexisting conditions in the context of COVID-19: bestpractice.bmj.com/topics/en-gb/3000190 BMJ Best Practice's topic...2020-08-1712 minQuestioning MedicineQuestioning Medicine139. COVID19, Mask, Kids, and More Terrible StudiesCharacteristics and Strength of Evidenceof COVID-19 Studies Registeredon ClinicalTrials.gov Looked at ClinicalTrials.gov identified 1551 studies registered fromMarch 1, 2011, to May 19, 2020,Lets look at the gold standard RCTOf the 664 RCT (76.1%) were single center. PROBLEM! Weather analysis!Only half of the rct looked at clinical course with only 8% of the rct looking at mortality and this is a problem because blinding was only reported for half of the trials so half of the time your outcome is clinical course and half the time you are not blinding them to the...2020-07-3127 minDeeper LevelsDeeper LevelsEpisode 20: ACE2 is having a moment: with special guest Dr. Ankit PatelDr. Patel’s articles:https://jamanetwork.com/journals/jama/fullarticle/2763803https://jamanetwork.com/journals/jama/fullarticle/2763803https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7314195/pdf/ciaa627.pdf2020-07-2754 minStraight To The PointStraight To The Point#2 "What's In A Vaccine?" with Edward Nirenberg & Steph MaryToday we are going to to take a multi-faceted approach to discussing vaccines. First, you'll hear a very powerful story from a former antivaccine single mother, Steph Mary, whose child got pertussis since she never got her them vaccinated. It is a powerful story, as well as somewhat intense (fair warning, there are a few f-bombs) but it's real, authentic and from the heart. After hearing Steph's experiences in leaving the antivaccine movement, we will hear from a biochemistry student Edward Nirenberg. Edward is a recent graduate from Cornell who studied macrophages in an immunology lab while working on...2020-07-161h 49Questioning MedicineQuestioning Medicine135. BABY BUMPERS! Plus 5 articles on July 4th https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2767257 still available for purchase in all states except New York, Maryland, and Ohio. Baby bumpers!! 2038 adults were surveyed (176 were parents of a child aged 2020-07-0424 minCLIMB4 PodcastCLIMB4 PodcastCLIMB4 Podcast #004 - Jason MaceFormer Army Infantryman Jason Mace, featured in Sebastian Junger's war documentary film "Restrepo," joins the show to speak about his experiences in the Korengal Valley, as well as continue the dialogue on PTSD, substance use, and helping to make an impact on veteran suicides. [Organizations mentioned during the show] Warrior's Heart (Strength through healing) - https://www.warriorsheart.com/ (https://www.warriorsheart.com/) [A Historical Examination of Military Records of US Army Suicide, 1819 to 2017] https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2757484 (https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2757484) [CLIMB4] ** CLIMB4 Fundraiser ( click here (https://www.climb-4...2020-06-2100 minStraight From The Cutter\'s Mouth: A Retina PodcastStraight From The Cutter's Mouth: A Retina PodcastEpisode 239: Journal Club with Dr. Priya Vakharia and Dr. Yoshihiro YonekawaFace-down positioning for macular holes randomized clinical trial (https://jamanetwork.com/journals/jamaophthalmology/fullarticle/2765648) Editorial on face-down positioning for macular holes (https://jamanetwork.com/journals/jamaophthalmology/fullarticle/2765646) Pseudophakic Retinal Detachments (https://www.aaojournal.org/article/S0161-6420(20)30428-0/fulltext) COVID-19 in NYC (https://www.aaojournal.org/article/S0161-6420(20)30430-9/fulltext) Mentoring Millenials (https://jamanetwork.com/journals/jama/fullarticle/2765430)2020-06-0838 minQuestioning MedicineQuestioning Medicine130. Antibiotics, BIOTOK and Knee Osteoarthritis, and Bempedoic AcidFox MT et al. Comparative effectiveness of antibiotic treatment duration in children with pyelonephritis. JAMA Netw vOpen 2020 May 1; 3:e203951. (https://doi.org/10.1001/jamanetworkopen.2020.3951) Rates of treatment failure did not differ significantly between the short and prolonged courses (11.2% and 9.4%). https://jamanetwork.com/journals/jama/fullarticle/2765729?guestAccessKey=2169ba8b-43fc-4360-bed7-acf7a31b1c9d&utm_source=silverchair&utm_medium=email&utm_campaign=article_alert-jama&utm_content=etoc&utm_term=051220Effect of Biomechanical Footwear on Knee Pain in People With Knee Osteoarthritis: The BIOTOK Randomized Clinical TrialIn...2020-05-1924 minNaruhodoNaruhodoNaruhodo #234 - Assistir à TV de perto causa miopia?"Não assista à TV tão de perto, minha filha, vai acabar precisando de óculos!"Quem nunca ouviu algo parecido?Afinal, fazer isso causa miopia?Confira no papo entre o leigo curioso, Ken Fujioka, e o cientista PhD, Altay de Souza.Convidada:Dra. Camila Kase - Graduada em Medicina pela Universidade Federal de São Paulo - Escola Paulista de Medicina. Médica Oftalmologista, também com atuação e pesquisa na área de medicina do sono.OUÇA (53min 19s)*Naruhodo! é o podcast pra quem tem...2020-05-1853 minNB Hot Topics PodcastNB Hot Topics PodcastS1 E16 - Children, coronavirus and Kawasaki-like disease; Hydroxychloroquine, azithromycin and cardiac arrest; antibody testing; non-coronavirus research!!!In this latest Hot Topics Podcast, Neal Tucker reviews the latest knowledge about coronavirus and non-SARs-CoV2 research relevant to primary care.We review new reports of Kawasaki-like disease in children with Covid-19 and the implications for children returning to school. We examine data on hydroxychloroquine and azithromycin suggesting it may kill more than it cures. And we have a think about testing and the new antibody tools.In non-coronavirus research, we look at SGLT2i and renal disease, P2Y12 inhibitors and CVD secondary prevent, whether GPs are successful in helping patients with weight loss...2020-05-1523 minQuestioning MedicineQuestioning Medicine129. Chronic Kidney Disease, Cholesterol LDL, Urinary Antigen Testing, Gout, Pharmaceutical Industry,https://jamanetwork.com/journals/jamainternalmedicine/article-abstract/2762699Association Between Renin-Angiotensin System Blockade Discontinuation and All-Cause Mortality Among Persons With Low Estimated Glomerular Filtration RateThe answer was no; In a 5-year follow-up, ACE-I/ARB discontinuation was associated with an increased risk of both mortality (hazard ratio, 1.39; 95% CI, 1.20-1.60) and major adverse cardiovascular events (hazard ratio, 1.37; 95% CI, 1.20-1.56).https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2762509Lobbying Expenditures and Campaign Contributions by the Pharmaceutical and Health Product Industry in the United States, 1999-2018pharma makes a lot of money—how do they sp...2020-05-1220 minNB Hot Topics PodcastNB Hot Topics PodcastS1 E15 - Coronavirus Special: Do The Drugs Work?In our latest Hot Topics podcast Neal Tucker examines the emerging treatments for Covid-19 including remdesivir, antiplatelets, vitamin D and vaccinations. Do these provide the magic bullet we need to shut down the infection and open up the world?He also reviews the latest research including data on asymptomatic and pre-symptomatic disease in children, important for when schools re-open, and the elderly, important for managing Covid-19 in care homes. He also looks at some emerging data on the extra-respiratory effects of the disease and how it may present in primary care.References:Children and...2020-05-0126 minAnesthesia and Critical Care Reviews and Commentary (ACCRAC) PodcastAnesthesia and Critical Care Reviews and Commentary (ACCRAC) PodcastEpisode 170: Lessons from 40 COVID Patients in the ICU with Brian GaribaldiIn this 170th episode I welcome Dr. Brian Garibaldi to the show to discuss his experience taking care of 40 critically ill COVID patients and what we’ve learned. We got through by system, head to toe, and discuss strategies and approaches. References: Lessons from China: https://jamanetwork.com/journals/jama/fullarticle/2762130 Convalescent Plasma: https://jamanetwork.com/journals/jama/fullarticle/2763983?widget=personalizedcontent&previousarticle=2762130 Management of patients with COVID: https://jamanetwork.com/journals/jama/fullarticle/2763879Our Sponsors:* Check out Eko: https://ekohealth.com/ACCRAC* Check out FIGS and use my code FIGSRX for a great deal: https://wearfigs.co...2020-04-071h 07F.A.Z. WissenF.A.Z. WissenCoronavirus: Können Blutspenden schwer Erkrankten das Leben retten?FAZ Wissen Chenguang Shen et al (2020), JAMA https://jamanetwork.com/journals/jama/fullarticle/2763983?guestAccessKey=57013f7d-97c6-46b8-b355-1245926c6548&utm_source=silverchair&utm_medium=email&utm_campaign=article_alert-jama&utm_term=mostread&utm_content=olf-widget_03282020 John Roback (2020), JAMA, Editorial https://jamanetwork.com/journals/jama/fullarticle/2763982?guestAccessKey=1e6f5d6a-8a7a-428e-bd95-276d3f128776&utm_source=silverchair&utm_medium=email&utm_campaign=article_alert-jama&utm_content=olf&utm_term=032720 Arturo Casadevall, Journal of Clinical Investigation https://www.jci.org/articles/view/1380032020-03-3122 minThe Critical NP PodcastThe Critical NP PodcastThe Coronavirus. Talking About COVID-19Discussing some of the details, data and relative information that we know as of 3/16/20 about the Coronavirus COVID-19 (SARS-CoV-2).⏺Incubation period⏺Presence on surfaces⏺Trialed treatment options⏺Testing⏺Symptoms⏺Epidemiological process since discoveryThis was a Facebook live recorded from my hotel room and unfortunately, I lost my WIFI signal abruptly so the broadcast was cut short.Here are some links of interest I spoke about, all free to download:Epidemiologic Features and Clinical Course of Patients Infected With SARS-CoV-2 in Singapore2020-03-1833 minBig Picture MedicineBig Picture Medicine#003 AlzEye, Deep Fakes and the Eye as a Window Into the Soul — Dr Siegfried Wagner (Moorfields Eye Hospital)What can 2 million retinal images and a machine-learning algorithm achieve? Early-detection of Alzheimers—at least that's what Dr Siegfried Wagner along with a team led by Dr Pearse Keane at the Moorfields Eye Hospital are working towards.  We discuss the study at Moorfields, before going down a deep dive into how a relatively novel AI technique—Generative Adversarial Networks (GANs) can be used in Medicine. You may have seen a number of 'deep fakes' online, all made using GANs. But what legitimate uses do they have in Medicine and research?  Mentioned Links AlzEye Study...2020-03-1522 minQuestioning MedicineQuestioning Medicine117. The Benefits on Healthy lifestyle and Nutritionhttps://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2757311?widget=personalizedcontent&previousarticle=2757307 Prior authorization requirements increased from 8% to approximately 24% of covered drugs on Medicare Part D plans between 2007 and 2019. Solutions-First, focus prior authorization on its intended purpose. Health plans should eliminate prior authorization requirements for medications that have very low final denial rates… this should only be for people that are outliersprotect continuity of patient care. For patients who are stable with chronic treatment, insurers should offer protections to minimize disruptions and inefficiencies—get a drug forever shouldn’t need to go off the drug o...2020-03-0134 minFinding HealthFinding HealthAre You Paying for Health Care You Don't Need?What is medical overuse? Dr. Morgan joins us this week to talk about care we may be getting that you may not need. It's not what you think.  Want to chat with us? Reach out on Twitter @finding_podcast www.twitter.com/finding_podcast (http://www.twitter.com/finding_podcast) Sources: https://jamanetwork.com/journals/jama/article-abstract/187987 (https://jamanetwork.com/journals/jama/article-abstract/187987) https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2294233 (https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2294233) Want to support the show? We're funded entirely by donors like you. Make a $10 donation today at reneecfrink.org (http://www.r...2020-02-2300 minQuestioning MedicineQuestioning Medicine112. Grade B, COPD, and Facebook for HIVhttps://jamanetwork.com/journals/jama/fullarticle/2751726 uspstf now grade B for asymptomatic urine in preggohttps://pediatrics.aappublications.org/content/144/6/e20192739kids do shoot their eye out!https://www.nejm.org/doi/full/10.1056/NEJMoa1908142Metoprolol does not treat COPDhttps://jamanetwork.com/journals/jamainternalmedicine/article-abstract/2754809?guestAccessKey=d3ef4800-287b-43aa-9d58-fd3c1e8359c2&utm_source=silverchair&utm_medium=email&utm_campaign=article_alert-jamainternalmedicine&utm_content=olf&utm_term=111819HIV and social media!!2020-01-1726 minFreiheit ohne DruckFreiheit ohne DruckLegalize it ... or not?! - Cannabis In der ersten Folge des neuen Jahres starten wir gleich in ein kontroverses Thema: Cannabis ist noch immer die meist konsumierte illegale Substanz in Deutschland. Und dass diese Substanz illegal ist und wie schädlich sie eigentlich ist, darüber existieren seit Jahren unterschiedliche Diskussionen auf politischer und fachlicher Ebene. Sollte man die Substanz legalisieren, wie es andere Länder schon vorgemacht haben? Was sind die Gefahren des Konsums? Diese und viele weitere Fragen beantwortet Dirk zusammen mit Prof. Dr. Derik Hermann, dem Chefarzt des Therapieverbundes Ludwigsmühle. Was ist eure Meinung zu Cannabis in Deutschland? Habt ihr noch Fragen zum...2020-01-1248 minThis Week In WellnessThis Week In WellnessTWIW 40: Maternal fluoride intake linked to lower IQ in kidsThis Week In Wellness JAMA paediatrics has published a study linking maternal fluoride exposure during pregnancy with lower IQ scores at 3 to 4 years of age. Fluoride has long been a hotly debated topic due to it’s potential neurotoxicity and that fast that the dosage when included in the water supply is hard to control. Fluoride is known to cross the placenta, accumulates in brain regions involved in learning and memory and alters neurotransmitters in the central nervous system. Water fluoridation is supplied to about 89% of Australians, 66% of Americans, 38% of Canadians, and 3% of Europeans. https://jamanetwork.com/jo...2019-12-1506 minQuestioning MedicineQuestioning Medicine109. Be Thankful One Article Will Change Your Practicehttps://jamanetwork.com/journals/jama/article-abstract/2753909?guestAccessKey=03d877eb-6d48-476f-9487-aa6fbbd8a8d5&utm_source=silverchair&utm_medium=email&utm_campaign=article_alert-jama&utm_content=olf&utm_term=103019https://jamanetwork.com/journals/jamainternalmedicine/article-abstract/2754091https://academic.oup.com/eurheartj/advance-article/doi/10.1093/eurheartj/ehz754/56024782019-11-2821 minQuestioning MedicineQuestioning Medicine107. Placebo, Opioid Prescribing, Cancer Screeninghttps://insights.ovid.com/crossref?an=00006396-900000000-98602https://jamanetwork.com/journals/jama/article-abstract/2751887?guestAccessKey=8fa2f772-1ba4-40ff-9015-4fcb46d6829e&utm_source=silverchair&utm_medium=email&utm_campaign=article_alert-jama&utm_content=olf&utm_term=091819https://www.ncbi.nlm.nih.gov/pubmed/14604741https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2749268?widget=personalizedcontent&previousarticle=0https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2749265https://www.jwatch.org/na44775/2017/08/10/nonsteroidal-anti-inflammatory-drugs-back-pain-andhttps://www.ncbi.nlm.nih.gov/pubmed/281538302019-11-1327 minScicastScicastCâncer de Próstata (Reimagine o Câncer #06)Queridos ouvintes, sejam bem-vindos ao sexto episódio do Reimagine o Câncer, uma parceria do Portal Deviante com a Novartis . Sendo este somente o quinto de uma série de episódios com o tema Câncer! Venha reimaginar conosco esse assunto tão complexo e fascinante.   Contatos: contato@scicast.com.br https://twitter.com/scicastpodcast Portal Deviante – Twitter Novartis Câncer Expediente: Produção Geral: Juliana Vilela, Marlyni Zens e  Tarik Fernandes. Host: Fernando Malta  Equipe de Pauta/Gravação: Marcel Ribeiro-Dantas...2019-11-1255 minGreener ThoughtsGreener ThoughtsThe Many Benefits of Vitamin DDon't think VITAMIN D is important, well think again! In this podcast episode find out ALL about the wonders this vitamin does, prevents, and helps make your body run - as it should. #healthybody #vitaminsandminerals #thestateofhealth #food #greenerthoughtspodcast Resources from the podcast: 1) https://onlinelibrary.wiley.com/doi/abs/10.1002/ana.22678 - Vitamin D and MS, 2) https://jamanetwork.com/journals/jama/article-abstract/2748796 - Vitamin D and calcium connection, 3) https://jamanetwork.com/journals/jamacardiology/article-abstract/2735646 - Vitamin D and heart health, and 4) https://www.healthline.com/nutrition/how-to-increase-vitamin-d - How to increase your vitamin D levels! ...2019-09-3035 minEmpowering Women PhysiciansEmpowering Women PhysiciansEpisode # 13 - The data on coaching physiciansIn this episode, Dr Sunny Smith shares the brand new Randomized Controlled Trial published in JAMA Internal Medicine documenting that coaching decreases distress and improves physician well-being.   Download your free self coaching guide here:  https://empoweringwomenphysicians.com/guide/   Main reference discussed in this podcast: Dyrbye LN, Shanafelt TD, Gill PR, Satele DV, West CP. Effect of a Professional Coaching Intervention on the Well-being and Distress of Physicians: A Pilot Randomized Clinical Trial. JAMA Intern Med. Published online August 05, 2019. doi:10.1001/jamainternmed.2019.2425 https://jamanetwork.com/journals/jamainternalmedicine/art...2019-09-0336 minQuestioning MedicineQuestioning Medicine102. DOAC and hematuria plus a listener questionhttps://jamanetwork.com/journals/jamainternalmedicine/article-abstract/2739056 not all guidelines are equal, think for yourself. Some guidelines even do harm when you actually look at the evidence. https://jamanetwork.com/journals/jamainternalmedicine/article-abstract/2740207 doacs and surgery what do you do-- low risk surgery stop one day prior and start one day after surgery. with high risk surgery you stop two days prior and start two days after https://jamanetwork.com/journals/jamainternalmedicine/article-abstract/2747871?guestAccessKey=90abe76b-3a15-4b95-9b42-4f751c5fbe64&utm_source=silverchair&utm_medium=email&utm_campaign=article_alert-jamainternalmedicine&utm...2019-09-0228 minStraight From The Cutter\'s Mouth: A Retina PodcastStraight From The Cutter's Mouth: A Retina PodcastEpisode 187: Journal Club Including Discussion of Gender Disparities in Resident Cataract Surgery, Informed Consent for Resident Involvement, Cost Effectiveness of Gene Therapy, and Surgical Errors in OphthalmologyDrs. Shriji Patel and Priya Sharma Vakharia join for a journal club about four recent publications in major ophthalmology journals. Article links below: Gender Differences in Resident Case Volume (https://jamanetwork.com/journals/jamaophthalmology/article-abstract/2738409) Preoperative Disclosure of Resident Involvement (https://jamanetwork.com/journals/jamaophthalmology/article-abstract/2739234) Cost-effectiveness of Gene Therapy (https://jamanetwork.com/journals/jamaophthalmology/fullarticle/2738410) Surgical Errors (https://www.aaojournal.org/article/S0161-6420(19)30859-0/fulltext) Dr. Patel and Dr. Vakharia have no financial disclosures. Dr. Sridhar has received consulting fees from Alcon, Alimera, and Thrombogenics. You can now claim CME credits via the AAO website. Visit https://www...2019-08-2641 minNaruhodoNaruhodoNaruhodo #195 - Beber suco de frutas aumenta o risco de câncer?Deu na Veja: "Segundo estudo, ingerir mais de 100 ml de suco industrializado ou natural por dia eleva o risco de câncer." Afinal, o que é fato e o que é factóide nessa matéria? Confira no papo entre o leigo curioso, Ken Fujioka, e o cientista PhD, Altay de Souza. OUÇA (41min 52s) Naruhodo! é o podcast pra quem tem fome de aprender. Ciência, senso comum, curiosidades, desafios e muito mais. Com o leigo curioso, Ken Fujioka, e o cientista PhD, Altay de Souza. Edição: Reginaldo...2019-08-1241 minQuestioning MedicineQuestioning Medicine97. Old Women Walking, Energy Drinks, and Antibioticshttps://www.ahajournals.org/doi/10.1161/JAHA.118.011318 energy drinks prolong the QT just ever so slightly in healthy 22yr olds so if you are thinking of telling grandma to slam 32ounces of energy drink and she is on QT prolonging medication then you probably shouldnt https://www.nejm.org/doi/full/10.1056/NEJMoa1808082 zolendranae is not a magic drug that cures osteopenia they just have magic trial makers the rigged the trial to show benefit https://jamanetwork.com/journals/jamainternalmedicine/article-abstract/2734709 in a study that looked at 7 days of step for 70 plus year old women it seemed that...2019-06-2825 minQuestioning MedicineQuestioning Medicine93. Breakfast, Tramadol, and Knee Osteoarthritishttps://www.bmj.com/content/364/bmj.l42 skip breakfast- it doesn't help you 'lose weight' https://jamanetwork.com/journals/jamainternalmedicine/article-abstract/2723074 Automated BP cuffs are the new rage and for good reason they are about equal to awake ambulatory blood pressure https://www.ncbi.nlm.nih.gov/pubmed/30653040 if you have a pt. going to surgery for their knee because of osteoarthritis-- let it be and DONT do an injection. https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(18)30191-1/fulltext if you have a choice-- give apixaban https...2019-05-0925 min