Shows
tv.qiagenbioinformatics.comImporting Single Cell Data into CLC Genomics WorkbenchSingle cell expression matrices can be imported into CLC manually using the import single cell matrix tool or they can be imported automatically using workflows. https://resources.qiagenbioinformatics.com/manuals/clcsinglecellanalysis/current/index.php?manual=Import_Expression_Matrix.html2025-04-0305 min
tv.qiagenbioinformatics.comPrecise Workflow Path Control using Branching ElementsDirect outputs through a workflow based on sequence count, coverage, and sample quality using branching elements https://resources.qiagenbioinformatics.com/manuals/clcgenomicsworkbench/current/index.php?manual=Branching_elements.html2025-04-0303 min
tv.qiagenbioinformatics.comIdentifying critical drug-to-disease pathways using high-quality curated...In the drug discovery pipeline, evaluating multiple pathways between a drug target and disease is crucial for identifying potential therapeutic approaches. By examining overlapping pathways between competing drugs, researchers can uncover novel drug targets, while isoform-specific findings may elucidate unexpected clinical trial outcomes. Filtering these pathways with real-world expression and proteomics data is essential to validate new hypotheses and avoid pursuing non-viable leads.
Leveraging tools such as Neo4j, Python, and R, powered by curated databases like the QIAGEN Biomedical Knowledge Base and OmicSoft Lands, enables scientists to efficiently explore potential mechanisms of action during both...2025-01-231h 01
tv.qiagenbioinformatics.comSingle - cell RNA-seq, cell hashing and spatial transcriptomicsIn this training, you will learn how to analyze and interpret your own single cell RNA-seq data using QIAGEN CLC Genomics Workbench starting with either FASTQ or matrix files.
Using CLC Genomics Workbench, you will learn how to perform secondary analysis on your single cell RNA-seq data. Specifically, you will learn how to:
• Import your raw FASTQ or processed cell-matrix files.
• Use pre-configured but customizable pipelines/workflows for single cell RNA-seq data.
• Generate high resolution visuals and other files from your analysis for publications and biopharmaceutical discoveries.
o Dimens...2025-01-231h 25
tv.qiagenbioinformatics.comDiscoveries from deeply curated TCGA expression data using OmicSoft StudioWhile there is great interest in the scientific community to investigate drug targets and biomarkers from public immune-oncology data sources such as The Cancer Genome Atlas (TCGA), such investigation is hindered by difficulties in finding and combining related datasets to perform large-scale meta-analyses. This webinar will focus on how high-quality curated genomic repositories such as QIAGEN OmicSoft Lands immediately allows in-depth investigations across diverse data sources (GEO, CPTAC, TCGA, GTEx and more) to discover and validate candidate checkpoint inhibitor drug targets and biomarkers.
You will discover how to:
• Use sample IDs...2025-01-231h 25
tv.qiagenbioinformatics.comSanger sequencing, alignment, cloning, primer design and more using QIAGEN...This training will be relevant to both QIAGEN Main and Genomics workbench users and prospects who are interested in below analytics.
• Alignment and tree construction
• Sanger sequencing analysis
• Cloning and primer design
• Other molecular biology tools
2025-01-231h 27
tv.qiagenbioinformatics.comIPA new user trainingAre you new to QIAGEN Ingenuity Pathway Analysis (IPA) or interested in expanding your skill set? Join us as we learn more on large dataset analysis and knowledge base queries using QIAGEN IPA.
You’ll learn to:
• Upload multiple dataset types (e.g., RNA-seq, proteomics, metabolomics) and perform interactive core/pathway analysis in IPA
• Learn how to interpret different results, including pathways, key regulators, impact on biological functions/diseases and more
• Compare different experimental conditions (e.g., single-cell clusters, disease types) and identify similarities and contrasts
• Ge...2025-01-142h 03
tv.qiagenbioinformatics.comInvestigating biomarkers with manually curated RNA-seq expression dataThere is a wealth of RNA-seq expression data scattered across public sources like GEO, SRA, TCGA and GTEx, but scientists interested in biomarker discovery need to devote significant time and resources to finding, cleaning and standardizing relevant data.
Start saving time with OmicSoft Lands, an accessible source of manually-curated, unified data available through both graphical user interface (GUI) and APIs.
We’ll cover how to:
- Easily find RNA-seq expression data of interest (specific diseases, drug treatments, tissues etc.) using the GUI and APIs
- Compare expression across customized conditions of...2024-12-161h 23
tv.qiagenbioinformatics.comMetabolome Genome-Wide Association Study (mGWAS) with the QIAGEN BKBs2024-12-1654 min
tv.qiagenbioinformatics.comUnderstanding Regulator Effects and Interaction Networks in QIAGEN IPANot sure what to do with Regulator Effects and Interaction Networks in IPA? After you conduct an IPA Core Analysis on your ‘omic dataset (RNA-seq, scRNA-seq, proteomics, metabolomics and more), start using the Regulator Effects and Interaction Networks results to interpret your data and generate hypotheses.
We’ll cover:
- Regulator Effects: These causal and directional networks connect major regulators with downstream diseases and biological functions
- Interaction Networks: These networks focus on the interconnectivity of molecules (genes, proteins, metabolites etc.) in your dataset
2024-12-161h 24
tv.qiagenbioinformatics.comGet started with QIAGEN CLC Genomics WorkbenchStart out strong with QIAGEN CLC Genomics Workbench and follow along with our live demo of its popular features.
We’ll cover how to:
Install and set up your Workbench
Add plugins like Biomedical Genomics Analysis plugin
Manage data with Reference Data Management
Work with reads and using tools and workflows to batch process your data
Visualize data with Track List and Genome Browser
Export data and share workflows
If you have any questions, we’ll answer them during the webinar.
2024-12-1653 min
tv.qiagenbioinformatics.comQIAGEN Public Health Virtual SymposiumThis event will feature four public health experts highlighting exciting collaborations within the PHL space across various workflows, including Antimicrobial Resistance Tracking, Vector-borne Disease Monitoring, Waterborne Pathogen Detection, and PulseNet Extraction/Sequencing. Come learn more about pathogen detection from the unseen heroes of public health!
The purpose of the QIAGEN Public Health Virtual Symposium is to inspire and equip public health professionals with the latest insights and innovative solutions to advance public health laboratory practices, fostering stronger collaborations and improving outcomes in public health initiatives.
Speakers:
Alex Rossheim, MS, Colorado Department of...2024-12-101h 55
Discovery and ResearchKnowledge graphs and more: Analytics-driven drug discovery using advanced...High-quality biomedical relationships knowledge is the cornerstone of modern and innovative data- and analytics-driven drug discovery. Yet this knowledge is locked in thousands of publications and dozens of databases. This webinar will show you how to unlock this knowledge and use it to strengthen your efforts in data science-driven drug discovery.
In this webinar, you'll learn about:
High-quality biomedical relationships knowledge: What it is and how to access it
Knowledge graphs and knowledge graph analysis
Artificial intelligence (AI)-driven target identification and drug repositioning using knowledge graphs and biomedical relationships
Disease subtyping...2022-07-1940 min
Discovery and ResearchDrug repurposing: from large-scale biological data to therapeuticsOne of the challenges we are facing today is the high cost and slow pace of drug development for many disease areas such as cancer, CNS, rare diseases etc. Repurposing drugs for new indications will have a shorter developmental time, lower cost, and less safety risk than the traditional drug development process.
Join us for this 60-minute Webinar on Drug repurposing: from large-scale biological data to therapeutics. This one-hour event will show how our platform enables biologists to leverage transcriptomics and literature-curated biological data for in-silico drug repositioning and repurposing.
Through a series of short...2022-07-081h 03
Discovery and ResearchWastewater and COVID-19 data analysis using QIAGEN CLC Genomics WorkbenchIn this 90-minute training, users will learn how to easily analyze wastewater samples to detect COVID-19 using QIAGEN CLC Genomics Workbench software.
Users will learn how to:
• Importing reads
• Open and modify prebuilt workflow (analysis pipeline)
• Install and execute workflow
• Review QC reports
• Visualization of genome
• Export of consensus sequence in FASTA format to upload to Pangolin
• Create a SNP tree of the consensus sequence and overlay Pangolin information
• Export graphical and tabular resultsLearn more about out SARS-CoV-2 resources here.2022-02-111h 12
Discovery and ResearchAdvancing drug discovery with organoid data analysis using QIAGEN Ingenuity...Three-dimensional (3D) cell culture structures like spheroids and organoids can be used to better understand complex diseases and deliver insights into potential theraputic opportunities. They are also complementary to two-dimensional (2D) cell cultures and in vivo models. These model systems offer scientists a detailed view of organ development, new insights on human development and disease, improving drug discovery and creating new approaches to precision medicine endeavors. Accordingly, this training will focus on using QIAGEN Ingenuity Pathway Analysis (IPA) and Omicsoft to study gene signatures in ‘omics data related to disease mechanisms and exploring drug action using organoid models.
Du...2021-12-141h 20
Discovery and ResearchDiscover hidden relationships in your toxicological studies with QIAGEN IPAQIAGEN Ingenuity Pathway Analysis (IPA) reveals the hidden upstream drivers and downstream outcomes in your toxicogenomics datasets. Put those results into context using Analysis Match with over 50,000 pre-analyzed datasets for human, mouse and rat. Explain the causes and effects in your studies so you can generate hypotheses to develop better drugs, biomarkers and more.
In this webinar you will learn how QIAGEN IPA:
• Is supported by QIAGEN’s Knowledge Base of over 7 million findings curated from the biomedical literature • Automatically makes predictions about toxicologically-relevant biology
• Provides contextually relevant results in seconds when used with the adde...2021-10-1849 min
Discovery and ResearchDiscovery from public oncological data using QIAGEN Omicsoft OncoLand and...In this 90-minute training, we will discuss how to discover and validate biomarkers as well as drug targets and key genes using public oncological data from GEO, TCGA, CCLE and other sources. To do this, we will use QIAGEN Omicsoft OncoLand, QIAGEN Ingenuity Pathway Analysis (IPA) and the OmicSoft Land Explorer web interface.
Specifically, for conditions of interest (diseases, cell lines, treatments etc.), we will discuss how to:
• Identify public studies of interest
• Derive a biomarker/gene signature
• Study expression of a gene or drug target
• Correlate expression of multiple genes and biomarkers
• Visualize...2021-06-241h 14
Discovery and ResearchUncovering Genomic Evidence of SARS-CoV-2 Infection and ReinfectionIs it possible to become reinfected with SARS-CoV-2? If so, how can we identify and confirm reinfection? What tools can we use to better identify prevalent and emerging strains of SARS-CoV-2?
Joel Sevinsky, Principal at Theiagen Consulting, is an expert in bioinformatics in the public health space and coauthor of a recent paper exploring the genomics evidence for reinfection with SARS-CoV-2 that was published in The Lancet Infectious Diseases. In this webinar, Dr. Sevinsky will discuss:
How next-generation sequencing (NGS) and off-the-shelf software confirmed the first documented SARS-CoV-2 reinfection case in the United States;2021-06-1752 min
Discovery and ResearchFrom data to biological insight using QIAGEN CLC Single Cell Module and...Organ development during gestation is a complex series of hematopoietic events. Many different lineages are involved at various stages, from pluripotent hematopoietic progenitors to the final differentiated cell types. Analyzing the cellular and molecular mechanisms of liver development is key to understanding the cell types that comprise this vital organ and the roles they play. We analyzed single-cell transcriptomes of human fetal liver to highlight the different cell type clusters and their biology.
In this webinar, we will discuss how to:
Analyze the data from FASTQ files from single-cell RNA-seq (scRNA-seq) to produce differential expression profiles...2021-06-1159 min
Discovery and ResearchInvestigation of Somatic and Germline Variants by COSMIC, HGMD and QIAGEN...Identifying and studying actionable variants is of great interest to many investigators. In this webinar, COSMIC, HGMD and QIAGEN database will be introduced for annotation and investigation of both somatic and germline variants.
Attendees will learn how to use QCI Interpret Translational (QCI-I T) to identify key actionable variants from whole-genome sequencing, whole-exome sequencing or DNA panels. In addition, attendees will learn how these variants can be annotated with findings derived from QIAGEN database in combination with COSMIC and HGMD. For variants of interest, it will be further demonstrated how COSMIC and HGMD databases can be further...2021-06-071h 24
Discovery and ResearchCalling, annotating and investigating genomic variants using QIAGEN CLC...In this 90-minute training, attendees will learn how to call SNPs, MNPs and structural variants (insertions, deletions, inversions and copy number variants) using QIAGEN CLC Genomics Workbench. In addition, we will demonstrate how to annotate these variants using both QIAGEN CLC Genomics Workbench and QIAGEN Clinical Insight Interpret Translational (QCII-T).
In this training, we will discuss the following topics:
• Variant calling from FASTQ or BAM files using QIAGEN CLC Genomics Workbench
• Variant annotation using QIAGEN CLC Genomics Workbench and QCI-IT
• Filtering variants based on quality score, genetic analysis and biological context
• Identifying causal and actionab...2021-06-011h 15
Discovery and ResearchRNA sequence analysis using PacBio and Illumina reads from a host-pathogen...Learn ways to accelerate your agrigenomics research and analyses in this 3-part webinar series that will take you through de novo assembly and annotation in non-model organisms, plastid assembly and long-read host-pathogen analysis in plants.
In this webinar learn from an expert in plant genetics and bioinformatics about Expression analysis using short and long reads in a host-pathogen interaction.
Who should watch: Plant geneticists, agricultural scientists, researchers studying non-model organism genetics, agrigenomics scientists, bioinformaticians, professors, directors, young scientists2021-05-2846 min
Discovery and ResearchSARS-CoV-2 NGS surveillance & epidemiology with QIAGEN Digital InsightsThis one-hour event will summarize our solutions for genomics research, environmental testing, and epidemiological study of SARS-CoV-2 NGS data, including:
Local and high-performance cloud (GCE) deployment
• Workflows for analyzing SARS-CoV-2 data using CLC Genomics software and focused approaches such as QIAseq SARS-CoV-2 Primer and Ion AmpliSeq SARS-CoV-2 panels.
• Analysis features, such as read mapping, consensus sequence, variant calling, and visualizations for efficient interpretation and cross-sample comparisons.
• Demonstration of local and cloud-based configurations of the CLC Genomics Server (GCE).
Fully Automated Analysis Service QIAGEN CoV-2 Insights Service
• Automated, high-thr...2021-05-141h 02
Discovery and ResearchAssembly and annotation of plastid genomes using QIAGEN CLC Genomics - Part 2Learn ways to accelerate your agrigenomics research and analyses in this 3-part webinar series that will take you through de novo assembly and annotation in non-model organisms, plastid assembly and long read host-pathogen analysis in plants.In this webinar learn from an expert in plant genetics and bioinformatics about denovo assembly and annotation of plastid genomesWho should watch: Plant geneticists, agricultural scientists, researchers studying non-model organism genetics, agrigenomics scientists, bioinformaticians, professors, directors, young scientists 2021-05-1142 min
Clinical and TranslationalOncology variant interpretation just got more preciseCompeting to offer a comprehensive genomic profiling service for solid or hematology oncology tumor samples is challenging, especially as panels increase in size and complexity. QIAGEN Clinical Insight (QCI) Interpret One is clinical decision support software integrated with professional variant interpretation services that enables rapid, evidence-based reporting of oncology NGS tests at scale.Connected to the world’s most comprehensive, manually curated knowledge base that is updated weekly, QCI Interpret One dynamically computes variant classifications according to AMP/ASCO/CAP and ACMG/AMP guidelines with full transparency. Users get access to over 200,000 pre-formulated, oncologist-reviewed variant interpretation summaries and ca...2021-05-1037 min
Clinical and TranslationalRapid, evidence-based reporting of oncology NGS tests at scaleCompeting to offer a comprehensive genomic profiling service for solid or hematology oncology tumor samples is challenging, especially as panels increase in size and complexity. QIAGEN Clinical Insight (QCI) Interpret One is clinical decision support software integrated with professional variant interpretation services that enables rapid, evidence-based reporting of oncology NGS tests at scale.Connected to the world’s most comprehensive, manually curated knowledge base that is updated weekly, QCI Interpret One dynamically computes variant classifications according to AMP/ASCO/CAP and EMA/ESMO/ELN/WHO guidelines with full transparency. Users get access to over 200,000 pre-formulated, oncologist-reviewed variant in...2021-05-1045 min
Discovery and ResearchGenome assembly evaluation and improvement of structural annotation in...Learn ways to accelerate your agrigenomics research and analyses in this 3-part webinar series that will take you through de novo assembly and annotation in non-model organisms, plastid assembly and long read host-pathogen analysis in plants.In this webinar learn from an expert in plant genetics and bioinformatics about genome assembly evaluation and annotation tools.Who should watch: Plant geneticists, agricultural scientists, researchers studying non-model organism genetics, agrigenomics scientists, bioinformaticians, professors, directors, young scientists 2021-05-1036 min
Discovery and ResearchEnabling High-Throughput Genomic Surveillance of Emerging SARS-CoV-2 Strains...In December 2020, the assumption that SARS-CoV-2 was a slowly-mutating virus began to change with the emergence of variants of concern in the United Kingdom and South Africa, the B.1.1.7 and B.1.351 variants, respectively. These lineages contained mutations in the spike protein that are estimated to increase the transmissibility of the virus by over 50% compared to earlier strains and provide potential avenues for immune escape. Unique spike protein mutational combinations continue to emerge globally, even in the first few weeks of 2021. While PCR is the clear choice for verification of diagnostic test results, next-generation sequencing (NGS) is the only high-throughput...2021-03-221h 08
Clinical and TranslationalIs your clinical NGS lab evidence-powered?Is your clinical NGS lab evidence-powered? A step every genetic and molecular testing lab should be doing with sequencing dataClinical NGS laboratories are currently facing multiple challenges: expanding test catalogs, vast literature, shrinking budgets, and increasing pressure to deliver test results faster, with greater detail, and pinpoint accuracy.The good news? The demands that face today’s clinical NGS labs have a solution: evidence-powered clinical decision support.In this free webinar, we will introduce a genomic variant analysis, interpretation and reporting solution that is being used by major labs and population-based screening health pr...2020-11-1157 min
Discovery and ResearchTranscriptomic analyses of in vitro flavivirus- or coronavirus-infected cell...The emergence of global viral infections reminds us of the significant public health issues brought about by these pathogens. In the last 30 years, new viral threats have arisen across the world, as exemplified by the recent COVID-19 pandemic. These viruses have had extensive impacts on human populations, and in many cases, have caused severe symptoms and even death. Therefore, understanding the immune response to these viruses is critical.
We have analyzed the transcriptomes of cell lines infected by these viruses, to highlight differences in the short-term (less than 36 hours) impact on host gene responses. In this web seminar...2020-09-0504 min
Discovery and ResearchMulti-omic changes in the postnatal mouse heart identified by QIAGEN...Multi-omics experiments allow researchers to make important discoveries in ways that have never before been possible. However, integrating these data into a broader biological context can be challenging and time consuming when using standard resources. At QIAGEN, we have introduced an innovative solution to this challenge: The market-leading QIAGEN Ingenuity Pathway Analysis (IPA) software integrated with our QIAGEN OmicSoft databases. In this webinar, Lynne Mullen, Ph.D., Senior Scientist, QIAGEN Digital Insights, will present a use case for QIAGEN IPA and QIAGEN OmicSoft in the analysis of changes in postnatal mouse heart tissues using transcriptomic, proteomic and metabolomic...2020-05-1803 min
Discovery and ResearchBiomedical genomics using QIAGEN CLC Genomics WorkbenchIn this webinar, Leif Schauser, Ph.D., Director Product Management, Genome Analysis at QIAGEN will describe common biomedical uses of QIAGEN CLC Genomics Workbench. In this informative webinar, you will learn about these topics, and more:
• Getting started with biomedical genomics
• Easy management of reference data
• Efficient algorithms for read trimming, mapping and variant calling
• Tailored solutions for RNA-seq, DNA-seq and methylation
• Ready-to-use workflows for tumor-normal, trios and families-of-four analyses
• Compatibility with reads from most platforms (Illumina, IonTorrent, BGI/MGI)2020-05-1203 min
Discovery and ResearchBacterial strain typing and genomics characterization of multi-drug...In this live webinar, we will present this tool and its utility for bacterial isolate identification, strain discrimination and detailed genomic analysis of multi-drug resistance. We will show bioinformatics analysis workflows built using QIAGEN CLC Genomics ProSuite for routine food testing and surveillance purposes. Finally, we will demonstrate methods using the QIAGEN Microbial Insights database and ARES Genetics’ ARESdb, two antimicrobial resistance genomic databases provided to QIAGEN CLC users seeking to identify the genetic determinants of AMR in bacterial pathogens.Interested in learning more?
Click here
2020-05-1248 min
Discovery and ResearchUsing QIAGEN Digital Insights to determine how LY6E impairs coronavirus...Zoonotic coronaviruses (CoVs) are significant threats to global health, as exemplified by the recent emergence of SARS-CoV-2. Host immune responses to CoV are complex and regulated in part through antiviral interferons. However, the interferon-stimulated gene products that inhibit CoV are not well characterized. In this webinar, we explain the findings of our recent study in which we identified LY6E as a broad coronavirus restriction factor. Our findings advance our understanding of immune-mediated control of CoV in vitro and in vivo and could help in the development of new strategies to combat infection by emerging CoV.In...2020-05-0603 min
Discovery and ResearchBioinformatics analysis of Nanopore sequencing data for SARS-CoV-2The study of the COVID-19 pandemic often involves sequencing the SARS-CoV-2 virus using Illumina, Nanopore, IonTorrent and Sanger technologies alone or in combination. Depending on the sampling and library preparation method used, this can involve metatranscriptomic data of varying viral content.
In this webinar tutorial, you will learn about:
· Best practices for bioinformatic analyses using the versatile QIAGEN CLC Genomics Workbench
· QC, adapter trimming and strategies for host read depletion and viral content enrichment
· Simple pipelines for assembly and strain identification
· A demonstration of read mapping, variant calling and conse...2020-05-0203 min
Discovery and ResearchTumor mutational burden analysis using QIAGEN CLC Genomics WorkbenchQIAGEN offers two analysis solutions for data acquired using QIAseq Kits. The GeneGlobe Analysis Center is our web-based portal with fixed, ready-to-use pipelines, while QIAGEN CLC Genomics Workbench is our onpremise solution providing ready-to-use workflows, which are fully configurable. QIAGEN CLC Genomics Workbench is a user-friendly bioinformatics software solution allowing comprehensive analysis, reporting and visualization of NGS data.
The following topics will be covered in this webinar:
• How to analyze data generated using the QIAseq Tumor Mutational Burden (TMB) and Microsatellite Instability Status (MSI) panels using QIAGEN CLC Genomics Workbench
• How to view and inte...2020-04-1639 min
Discovery and ResearchScaling your bioinformatics with QIAGEN CLC Genomics Server and Cloud EngineIn this webinar, you will learn how to use QIAGEN Digital Insight’s enterprise solutions to extend the powerful QIAGEN CLC Genomics Workbench platform to tackle even the greatest bioinformatics challenges. These topics will be discussed in this webinar:• Overview of QIAGEN CLC enterprise solutions• Case studies demonstrating the utility of QIAGEN CLC Genomics Server and QIAGEN CLC Genomics Cloud Engine, including examples of our Biomedical Genomics Analysis plugin for RNA-seq gene expression analysis, analysis of QIAseq panels for somatic variant calling and analysis of microbiome and antimicrobial resistance data using QIAGEN CLC Microbial Genomics Module...2020-03-2647 min
Case StoriesDr. Kambiz Karimi about the comprehensiveness of QIAGEN clinical insightsDr. Kambiz Karimi, Curation Manager at Counsyl, presented data as ASHG which shows how comprehensive QCI is when compared against Counsyl’s own data sets. It also shows how much time they save. As a result, they now want to automate the integration of QCI bibliographies in their workflows.Interested in learning more?Click here2020-02-1703 min
Case StoriesBjarni Vilhjalmsson on data to sample to insight workflows helping cancer...At ASHG, Bjarni Vilhjalmsson presents data on sample to insight workflows that help cancer researchers to improve their variant accuracy. He has integrated the v3 chemistry QIAseq panels that feature unique molecular indices and single primer extensions together with QIAGEN bioinformatics solutions and found 8 times higher accuracy levels.Interested in learning more?Click here2020-02-1702 min
Case StoriesThe importance of a good bioinformatics pipeline for determining TMB scoreTumor mutational burden is an important biomarker for immuno-oncology. Dr Ravindra Kolhe from the University of Augusta discusses the benefits of the QIAGEN Clinical Insight bioinformatics pipeline for calculating TMB score.Interested in learning more?Click here2020-02-1702 min
Case StoriesThe importance of molecular testing to improve cancer patient outcomes - Dr....Dr. Allan Njau, Anatomical Pathologist at the Aga Khan University Hospital, Kenya, discusses the importance of molecular testing to improve cancer patient outcomes.Cancer incidence rates in Kenya are high and accompanied by elevated morbidity and mortality. Dr. Allan Njao discusses how molecular NGS testing paired with a comprehensive bioinformatics analysis and reporting pipeline, can help improve cancer patient outcomes.Interested in learning more?Click here2020-02-1702 min
Case StoriesDr. Sehime Temel of the Department of Medical Genetics at Uludag University...Trying to find the appropriate genetic variant without bioinformatics is as impossible as “trying to find a single fish in the ocean”. Dr. Sehime Temel, of the Department of Medical Genetics at Uludag University in Turkey, explains how QCI Interpret is the magical tool that allows for diagnosis within a day rather than 6 months.Interested in learning more?Click here2020-02-1701 min
Case Stories#AACR19 Interview with Deep PandyaDeep Pandya, Bioinformatician at the Western Connecticut Health Network, speaks about presenting their novel liquid biopsy approach and QIAGEN support when facing challenges in analyzing large amounts of genomic data.Interested in learning more?Click here2020-02-1702 min
Discovery and ResearchQIAGEN CLC Genomics Workbench 20 – scalable desktop software for NGS data...In this webinar, Leif Schauser, Ph.D., Director Product Management Genome Analysis, will review the latest features in the new QIAGEN CLC Genomics Workbench 20. The following topics will be covered:
• One-click solutions and expert tools for NGS data analysis
• Working with reads from various platforms (Illumina, IonTorrent, Oxford Nanopore, Pacific Biosciences, BGI/MGI)
• Tailored solutions for RNA-seq, DNA-seq and methylation
• Efficient algorithms for read trimming, mapping, de novo assembly and variant calling
• Effective management of reference data
• Scalable processing of many samples, with advanced workflow and reporting capabilities
• Easy installation on Windows, Mac and Linux2020-01-2853 min
Discovery and ResearchQIAGEN CLC Genomics Workbench 20QIAGEN CLC Genomics Workbench 20 key featuresInterested in learning more?Click here2019-12-1002 min
Discovery and ResearchTranscriptomics, Proteomics and Metabolic Changes in Post-Natal Mouse Heart...In this talk, Jean-Noël Billaud, Ph.D. Senior Principal Scientist, QIAGEN Digital Insights presents a use-case for QIAGEN IPA and QIAGEN OmicSoft in the analysis of changes in post-natal mouse heart tissues. In the talk Dr. Billaud discusses:
Sample to Insight workflows
Processing and uploading of transcriptomics, proteomics, and metabolomics data
Biological analysis of the data types
Interpreting the results in a larger context
Conclusions
Interested in learning more or trying IPA? Click here.2019-11-0728 min
Discovery and ResearchDetecting antimicrobial resistance in extensively drug-resistant Salmonella...Infections caused by drug-resistant bacteria are increasingly reported and antibiotic resistance is now recognised as one of the major threats to global public health. Whole genome sequencing has become an important method for understanding antimicrobial resistance determinants and for surveillance of the emergence and spread of resistant bacteria and the underlying genetic mechanisms of resistance.
In this webinar, we demonstrate how tools of CLC Microbial Genomics Module can be used to identify antimicrobial resistance markers from the genomes of pathogenic bacteria using a case of extensively drug-resistant Salmonella enterica serovar Typhi from a clonal spread in Pakistan.2019-07-0528 min
Discovery and ResearchCharacterizing the microbiome by targeted sequencing of bacterial 16S rRNA...Bacterial communities are everywhere. The microbiome profoundly
affects human, animal and environmental health. The main questions when
investigating microbial communities are which microorganisms are
present, how abundant are they and how are they interacting with their
host or environment?
We demonstrate taxonomic profiling of bacterial and fungal
communities with QIAGEN Microbial Genomics Pro Suite tools, using a case
of decomposing beech leaves.
Decomposition of leaf material is a dynamic process where the
composition of the litter changes continuously. To accommodate
nutritional fluctuations, the microbial community must be diverse and
dynamic. We analyze the changes in...2019-07-0521 min
Discovery and ResearchExploring Single-Cell Transcriptomes Using Bioinformatics Solutions from...Cells – the basic building blocks of organisms – are each quite unique. Single-cell RNA sequencing has emerged as an important technology to dissect cellular heterogeneity and tissues into cell types and/or cell states, offering enormous de novo discovery potential.
In this webinar series, you’ll gain an in-depth look at two major bioinformatics solutions from QIAGEN - OmicSoft Array Studio and Ingenuity Pathway Analysis (IPA). Together, both offer a powerful, yet easy to use, solution for the analysis and interpretation of whole transcriptome datasets from single-cell sequencing experiments. Become confident in how to optimize transcriptome data, and how using IP...2019-07-0541 min
Discovery and ResearchExploring Single-Cell Transcriptomes Using Bioinformatics Solutions from...Cells – the basic building blocks of organisms – are each quite
unique. Single-cell RNA sequencing has emerged as an important
technology to dissect cellular heterogeneity and tissues into cell types
and/or cell states, offering enormous de novo discovery potential.
In this webinar series, you’ll gain an in-depth look at two major
bioinformatics solutions from QIAGEN - OmicSoft Array Studio and
Ingenuity Pathway Analysis (IPA). Together, both offer a powerful, yet
easy to use, solution for the analysis and interpretation of whole
transcriptome datasets from single-cell sequencing experiments. Become
confident in how to optimize transcriptome data, and how...2019-07-051h 08
Clinical and TranslationalHGMD : Empowering a Generation of Geneticists for Precision MedicineThe Human Gene Mutation Database (HGMD) is a manually curated, comprehensive collection of disease-causing, germline mutations. Since 1996, a team of experts has manually catalogued over a quarter of a million mutations for the database.This talk will feature a retrospective view of HGMD, how it has grown over time, and the research that it has enabled. In particular, our speakers will talk about how HGMD has helped move precision medicine forward by providing translational research and diagnostic applications with the most comprehensive survey of literature on genetic mutations responsible for human inherited diseases, supporting standardized interpretation for germline...2019-04-1056 min
Clinical and TranslationalRapid and comprehensive NGS variant interpretation using web-based softwareNGS presents clinical laboratories with an ever-increasing amount of novel sequence variants that need to be interpreted in terms of their clinical relevance as transparently, accurately, and as fast as possible. In order to minimize inconsistencies between different labs, various guidelines for variant interpretation have been developed. Although these guidelines are very useful, they require a large set of criteria (like the 28 criteria of the American College of Medical Genetics and Genomics) that need to be assessed and checked for each variant. Doing this manually is very time-consuming.Dr. Andreas Rump of the Institute for Clinical Genetics at...2018-12-1358 min
Discovery and ResearchCLC Genomics Workbench 12Introducing CLC Genomics Workbench 12 – an exciting new release that’s making it easier and faster for you to gain new sample to research insights.Interested in
learning more?
Click here2018-11-2702 min
Discovery and ResearchExploring IPA’s Analysis Match: An OverviewLearn about the new Analysis Match features and discover a new way to
explore biological results
Analysis Match enhances interpretation and drives discovery by placing
your dataset in the context of over 49,000 IPA analyses that have been processed
from public sources using OmicSoft’s Array Suite.
Powered by IPA Advanced Analytics, Analysis Match automatically
identifies curated IPA datasets with significant similarities and differences,
enabling you to compare results, validate interpretation and better understand
causal connections between diseases, genes, and networks of upstream
regulators.
Check out our short w...2018-11-2602 min
Clinical and TranslationalCase Study: Genetic Testing Lab Sees 25-Fold Scaleup with QIAGEN Clinical...This webinar offers a look at how an advanced genetics laboratory implemented and validated QIAGEN Clinical Insight (QCI) Interpret to help scale operations and cut costs.William Kearns, founder of genetics testing lab AdvaGenix, will share his team’s experience as it sought to increase its testing throughput while maintaining high quality standards. After studying the time and cost associated with building and validating a bioinformatics platform from scratch, as well as the cost of maintaining such a system, the AdvaGenix team decided to look for commercial solutions.AdvaGenix needed a solution that adhered to pr...2018-11-0150 min
Discovery and ResearchIntroduction to OmicSoft LandPortal: Expression ViewsOmicSoft uses ArrayLand framework to deliver large amounts of clinical and "omic"-data to biologists with simplistic visualization. Land Explorer is the quickest way to explore OmicSoft Land data (OncoLand, DiseaseLand, GeneticsLand, and Internal Lands). Users of Array Studio may be familiar with the content provided within the Land Explorer framework. The streamlined web interface uses our most popular visualizations to help researchers and clinicians explore OmicSoft Lands.
This video demonstrate the utility of Land Explorer, including a description of the many views available, as well as the general usage and customizations of these views.Interested...2018-07-3104 min
Clinical and TranslationalGenomics guided precision medicine with QCI Interpret: Discover how easy it...Do you need a clinical reporting solution that is highly accurate, reproducible and standardized?If you answered yes, we invite you to watch a free recording of our webinar that addresses one of the key bottlenecks of today’s clinical testing laboratory: producing standardized interpretation that is consistent among personnel, reproducible within the testing community, and in accordance with professional guidelines.Dr. Beate Litzenburger, Senior Somatic Scientist at QIAGEN, demonstrates step-by-step how QCI Interpret not only automates AMP/ASCO/CAP and ACMG/AMP guidelines, but gives you full transparency into the underlying evidence supporting the classification. You ar...2018-06-2838 min
Clinical and TranslationalLeveraging QIAGEN's panel in breast cancer with Dr. Fergus CouchDr. Fergus Couch of the renowned Mayo Clinic explores hereditary cancers and investigates the role of gene mutations using QIAGEN’s panel. In the video he talks about his findings in pancreatic cancer and his plan to leverage the panel in breast cancer.Visit qiagenbioinformatics.com2017-11-2003 min
Clinical and TranslationalDr. Kambiz Karimi about the comprehensiveness of QIAGEN Clinical InsightsDr. Kambiz Karimi, Curation Manager at Counsyl, presented data as ASHG which shows how comprehensive QCI is when compared against Counsyl’s own data sets. It also shows how much time they save. As a result, they now want to automate the integration of QCI bibliographies in their workflows.Visit qiagenbioinformatics.com2017-11-2003 min
Discovery and ResearchThe pathogenesis of crohn's disease with Ingrid ArijsIngrid Arijs of the University in Leuven explores the pathogenesis of crohn’s disease and talks about the insights into biological pathways she is getting from IPA for her research.
Visit qiagenbioinformatics.com2017-11-2002 min
Discovery and ResearchAndreas Rump investigates the genetic causes of intellectual disability in...Dr. Rump from the Technical University of Dresden investigates the genetic causes of intellectual disability in children, and calls for a unified platform to share variants.Visit qiagenbioinformatics.com2017-11-2002 min
Discovery and ResearchBjarni Vilhjalmsson on data to sample to insight workflows helping cancer...At ASHG, Bjarni Vilhjalmsson presents data on sample to insight workflows that help cancer researchers to improve their variant accuracy. He has integrated the v3 chemistry QIAseq panels that feature unique molecular indices and single primer extensions together with QIAGEN bioinformatics solutions and found 8 times higher accuracy levels.
Visit qiagenbioinformatics.com2017-11-2002 min
Discovery and ResearchExploring variants associated with rare diseases - Peter Bauer, MD InterviewProfessor Bauer, CSO of Centogene, discusses the prospects for researchers exploring variants associated with rare diseases in the light of the new collaboration with QIAGEN, and how patients suffering from these diseases may ultimately benefit from this.
Visit qiagenbioinformatics.com2017-11-2003 min
Discovery and ResearchQIAGEN RNA sequencing solutions – from Sample to InsightInterested in
learning more?
Click here2017-06-0700 min
Case StoriesDr. John Martignetti comments on RNA researchFor years, RNA research lagged behind investigations of DNA. Now, a growing understanding of RNA’s vital role in regulating normal physiology is attracting increasing interest - revealing a powerful driver of both disease and health.2017-04-1203 min
Case StoriesIdentifying rare disease variantsDr. Rump, PhD, head of Molecular Genetics Group at the Institute for Clinical Genomics in Dresden, uses Biomedical Genomics Workbench to compare exomes in rare and inherited diseases, and to identify the cause of the disease. With increasing amounts of variant and annotation data, the right informatics tools and techniques are indispensable for Dr. Rump and his team, allowing them to not only create the data via NGS but also to explore it and formulate new ideas.2017-01-1002 min
Case StoriesClinical genomic sequencing: Where we’ve been, where we are, and where we’re...Presented by Dr. Josh Deignan, Ph.D., F.A.C.M.G.2016-11-0747 min
Clinical and TranslationalIntroduction to QIAGEN Clinical Insight (QCI) for Somatic Cancer2016-09-1402 min
Clinical and TranslationalBioinformatics: Gaining insights from genomic dataSpurred by NGS technologies, more genomic data is generated today than in the entire history of mankind before. Advanced bioinformatics tools help to analyze and interpret these vast amounts of data to generate valuable insights.2016-08-0504 min
Clinical and TranslationalQIAGEN Clinical Insight Demo, ASCO 2016Clinical bioinformatics expert Naomi Thomson gives a short introduction into QIAGEN's clinical decision support platform QIAGEN Clinical Insight.2016-08-0503 min
Discovery and ResearchRNA sequencing solutions from QIAGEN Bioinformatics2016-08-0403 min
Case StoriesTranscriptome analysis of Kupffer cells after uptake of pancreatic cancer exomesPresented by Principal Scientist, Dr. Jean-Noel Billaud, at AACR 20162016-05-3039 min
Case StoriesCenter for Genomic Medicine, Rigshospitalet - The Phase 1 projectFinn Cilius Nielsen and Lars Jønson at Center for Genomic Medicine work closely with the Phase I Unit, looking to decide whether deep sequencing of tumors will provide data that can be used for treatment of patients and improve their survival in the long run. 2016-05-1905 min
Case StoriesTargeted RNA sequencing, Urban Metagenomics, and Astronaut GenomicsDr. Chris Mason’s presentation covers the QIAseq Targeted RNA Panel beta testing, QIAGEN’s Sample-to-Insight solution for Metagenomics sequencing as demonstrated in the Metasub project, as well as Chris latest endeavor the, “Twins Study”, which will be a comprehensive genomic study of the impact of spaceflight on the human body. Astronaut Scott Kelly will be studied during the course of his year-long stay at the ISS as will his twin brother, Mark Kelly, a former NASA astronaut who will remain on earth.2016-05-1041 min
Clinical and TranslationalIntroduction to QIAGEN Clinical Insight (QCI) for OncologyReady to reveal the clinical significance in NGS variants? QIAGEN Clinical Insight allows you to use the same solution for drug labels, clinical trials and professional guidelines all in one place. We offer the most comprehensive content available for biomedical findings.2016-05-0301 min
Case StoriesCenter for Genomic Medicine - RigshospitaletCenter for Genomic Medicine works closely with the Phase I Unit, looking to decide whether deep sequencing of tumors will provide data that can be used for treatment of patients and improve their survival in the long run. 2016-04-2501 min
Case StoriesXSQ supportProf. Robert Donnelly and his staff at Rutgers use the 5500 SOLiD system for large-scale sequencing projects, and they save a lot of time being able to import the SOLiD XSQ files directly into CLC Genomics Workbench.2013-12-1101 min
Case StoriesPubertal onset researchA recent project at Rigshospitalet is correlating longitudinal clinical measurements to sequence data.2013-11-1102 min
Case StoriesColon cancer projectProf. Sun from the National Cheng Kung University College of Medicine in Taiwan shares how she handles large amounts of data while working towards making new discoveries.2013-04-1102 min
Case StoriesGenome sequencing of human pathogensBy sequencing important bacterial pathogen genomes, Dr. Chiu, from Chang Gung Children's Hospital in Taiwan, hopes to provide new knowledge to the medical community.2013-03-1202 min
Case StoriesGlaucoma Research in JapanDr. Tashiro from Kyoto Medical University elucidates the molecular mechanisms of Glaucoma. He works towards identifying the pathogenesis of the eye disease together with his team.2013-02-1202 min
Case StoriesComputational resources for NGS research at University of PittsburghThe University of Pittsburgh and UPMC use informatics and computing infrastructure for clinical high-throughput sequencing.2012-12-1103 min
Case StoriesPopulation adaptive divergence studies on whitefish in CanadaDr. Louis Bernatchez from IBIS, Laval University, elaborates on their projects.2012-09-1002 min
Case StoriesKing Cobra ProjectRon Dirks from ZF-screens elaborates on the King Cobra project, in collaboration with BaseClear.2012-08-1303 min
Case StoriesCystic fibrosis research at IBIS, Laval UniversityDr. Roger C. Lévesque from IBIS, Laval University in Quebec City, elaborates on their cystic fibrosis and lung cancer research.2012-07-1002 min
Case StoriesNon-profit development of disease-resistant cassava for farmers in AfricaDr. Claude M. Fauquet elaborates on how the not-for-profit Donald Danforth Plant Science Center in St. Louis, is mixing science and technology to improve agricultural production of cassava to make a difference for millions of people in Africa.2012-06-0502 min
Case StoriesThe Rubber Genome Project - Sequencing of the white blood of the world economyRubber Genome, white blood, Draft Genome Publication, Malaysia, Centre for Chemical Biology, Dr. Alam2012-03-1503 min
Case StoriesJCVI: Drive your science forwardJCVI focus on new cutting edge tools giving them the advantage to drive the science forwardInterview with Indresh Singh, Lead, Informatics Core Service, JCVI:"Analysis is the bottleneck. Analysis costs and disk storage costs is going up, so the only solution is to analyze the data faster."2011-10-1803 min
Case StoriesFABI investigating the genome of a fungus causing the pitch canker diseaseInterview with Dr. Martin Coetzee, Senior Lecturer, Department of Genetics and Researcher at Forestry and Agricultural Biotechnology Institute (FABI) and Dr. Arshad Ismail, GS Technology Platform Manager, Inqaba Biotec.2011-09-0803 min
Case StoriesInvestigating ancestral polyploidy in plants at Penn StateInterview with Dr. Claude dePamphilis, Professor of Biology at Penn State University.2011-08-1608 min
Case StoriesARC establishes South African bioinformatics network for agricultural researchInterview with Dr. Jasper Rees, Head of the Biotechnology Platform, Agricultural Research Council (ARC), South AfricaIn order to address their key strategic areas of improving food security, increasing crop productivity, Agricultural Research Council recently made two large investments.The first in a complete High-Throughput Sequencing platform solution allowing them to incorporate both NGS and advanced genotyping technologies into a single instrument.The second investment was made in the area of bioinformatics – hardware and software. The core of this investment sits with an enterprise platform enabling them to effiently distribute genomics tools and bi...2011-05-1203 min
Case StoriesUsing RNAi to regulate gene expression in cancer and TTRHead of Informatics, Greg Hinkle, PhD, Alnylam Pharmaceuticals elaborates on the potential of RNAi, including examples in liver cancer, and TTR.2011-02-0803 min
Case StoriesUse your valuable bioinformatics staff for breaking new groundsAssociate Director at ICBR, University of Florida, Dr. Bill Farmerie, says today's challenge is not dealing with the instruments themselves, but the data that comes off them.2010-12-0903 min
Case StoriesRNA-Seq milk cell transcriptome research at UC DavisAt present UC Davis are working on improving the content of oligosaccharides in bovine milk.Working on an initiative referred to as the Foods for Health Institute, whose goal is to improve human health through food.See Professor Juan F. Medrano, PhD from the Animal Genomics Laboratory, UC Davis elaborate on their exciting project.2010-11-0903 min
Case StoriesScience as a Service by EdgeBioDirector of Bioinformatics at EdgeBio, Justin H. Johnson, elaborates on the concept of Science as a Service at CHI's "Beyond Sequencing" conference in San Francisco, June 2010.2010-08-3002 min
Case StoriesDouble haploid apple genome project in South AfricaProfessor Jasper Rees and Dr. Joseph Mafofo from the University of the Western Cape, South Africa, shares some preliminary results and challenges from their Golden Delicious apple genome sequencing project.2010-06-1803 min
Case StoriesGenome project - Research on plant diseasesSee how CLC bio's de novo assembler is making research easier for Eva Stukenbrock, Postdoc, Cand. Scient. PhD at BiRC, Aarhus University2010-06-1703 min
Case StoriesLupus erythematosus research by OMRFResearchers at the Oklahoma Medical Research Foundation elaborate on their sequence capture approach to identifying novel genes that are linked to Lupus erythematosus.2010-06-1704 min
Case StoriesX-Linked mental retardation study from the Max-Planck InstituteScientist, Jeremy Lambert, from RainDance elaborates on how their microdroplet technology, high-throughput sequencing, and CLC bio’s bioinformatics tools can be used in resequencing projects to effectively speed up the process of analyzing complex diseases. In this video examplified by a publication on X-Linked mental retardation from the Max-Planck Institute.2010-06-1702 min