Shows
Honest Garage PodcastModernize the Legacy: Steve Horvath on Shop Expansion, Industry Networking, and Educating DriversSteve Horvath literally grew up in the automotive business—then spent decades evolving a family legacy into a modern, trusted operation. Steve is the owner of Gino's Auto Service in Littleton, Colorado, a AAA-approved shop that's been serving the community since the early 1980s. In this episode, Steve breaks down what it really looks like to expand and modernize a long-standing facility—without losing the "neighborhood shop" feel that built the reputation in the first place. https://www.jenosautoservice.com/ You'll hear Steve's real-world lessons from adding space and bays (including the stuff nobo...
2026-02-0927 min
KGRA Digital Broadcasting DiscoveryU.S. Transhumanist Party Virtual Enlightenment Salon - TransVision Madrid 2025 SummitOn Sunday, December 21, 2025, at 1 p.m. U.S. Pacific Time, watch the fifth stream from the TransVision Madrid 2025 International Longevity Summit, which took place on October 1-2 in Madrid, Spain. The U.S. Transhumanist Party has allied with TransVision Madrid and Alianza Futurista, its fellow transhumanist political party in Spain, to bring you six more presentations by distinguished scientists, doctors, and longevity advocates.The presentations included in this compilation stream include the following:- Dr. Eduardo Díaz-Rubio, President of the Royal National Academy of Medicine of Spain, specialist in internal medicine and oncology, presented his outlooks on i...
2025-12-211h 50
The Bulldog Brewhouse PodcastWhy Mental Health Matters with Kyle Horvath from The Newly InstituteWhy is mental health the core of everything we do? On this episode of the Bulldog Brewhouse Podcast, we sit down with Kyle Horvath of The Newly Institute to unpack the profound importance of mental wellness. We go beyond the surface to discuss how mental health impacts our relationships, work, and daily happiness. Get ready to rethink what's possible for your own well-being.
2025-11-2853 min
Extra TakesExtra Takes November 19, 2025. Josh Laxton and Tom HorvathMatt Shiles sits this one out as Tom Horvath steps in as the backup QB. After a brief synopsis of Steve Brown's message this weekend, Pastor Josh tells about his trip to Buchanan Tennessee, where he preached on Acts 1 and the beginnings of the church. Join us for this unique episode of Extra Takes!
2025-11-1947 min
Transhumanist Party Enlightenment SalonTransVision Madrid 2025 Summit: Longevity March, Omniscope, Gil Rodas, Steve Horvath, Michael RingelOn Sunday, October 26, 2025, at 1 p.m. U.S. Pacific Time, watch a stream of notable events that transpired in Madrid, Spain, on October 1, 2025, International Longevity Day, including the March for Longevity and presentations of various approaches in the fight against aging and disease by Vijay Vaswani, Holger Heyn, Gil Rodas, Steve Horvath, and Michael Ringel.The stream begins with the March for Longevity that took place in Madrid on International Longevity Day, October 1, 2025. The march took participants through some of the main streets and plazas of Madrid and ended in front of Madrid City Hall, all the while a...
2025-10-261h 56
Brain, Hope, Reality: PTSI not PTSD | Hosted by Dr. Eugene LipovEP10 | Epigenetics and PTSI | Robert (Bobby) Brooke, CEO of the Nonprofit Clock FoundationCan PTSD accelerate aging — and can reversing it make you biologically younger? Dr. Lipov talks with epigenetics expert Bobby Brooke about stress, longevity, and the power of measurable healing.- - In this engaging episode of Brain, Hope, Reality, Dr. Eugene Lipov speaks with Robert (Bobby) Brooke, CEO of the nonprofit Clock Foundation and collaborator with epigeneticist Dr. Steve Horvath. The conversation explores the field of epigenetics, particularly how trauma and stress can accelerate biological aging through changes in gene expression — changes that are measurable and, crucially, reversible. They discuss the development of epigenetic clocks like...
2025-09-1140 min
Forever YoungForever Young | Official TrailerForever Young is a feature-length documentary premiering at the 2025 Mill Valley Film Festival. The completion of the film marks the beginning of our Substack journey, where our team will dig deeper into the topics, questions, and controversies covered in this sweeping documentary that blends science and humanism. To watch the documentary, click here to register for a virtual screening.Directed by David DonnellyProduced by James B. Johnson, MD, and Thomas B Lewis, MDOur cast includes: James B. Johnson, MD: Dr. Johnson is a retired plastic...
2025-08-2002 min
Drive RadioFIX IT RADIO: When Memories Meet the Dumpster: How to Let Go Without Losing What Matters Most. 8-9-25The show kicks off with a sunny Saturday morning on https://FixIt-Radio.com, where John Rush and Steve Horvath dive into a surprisingly emotional and practical topic—tackling the daunting task of sorting through a lifetime of belongings. From the overwhelm of inherited estates to the “four box method” of keep, donate, toss, or relocate, John shares his methodical approach to staying sane while decluttering. But this isn’t just about organization—it’s about making tough calls, dealing with sentimental ties, and finding the right systems to move forward. Just as the conversation gains momentum, a caller shifts gears to a unique...
2025-08-1158 min
LEVITY#26 Inside Shift Bioscience’s single-gene rejuvenation breakthrough — Exclusive with CEO Daniel IvesJust about the hottest thing in longevity science right now is partial reprogramming - using Yamanaka factors to rewind the biological clock in our cells. Billion-dollar giants like Altos, Retro and New Limit are betting on it.But in this episode a far smaller player, Shift Bioscience, argues that the field may be looking in the wrong place. CEO Daniel Ives explains how his team used AI-powered virtual cells to uncover a single gene that seems to match OSK-level rejuvenation without the tumor risk that haunts classical reprogramming - and why their just-released data could change the...
2025-06-171h 59
Don’t Miss An Eye-Opening Full Audiobook And Elevate Your Mindset.Sledge vs. The Labyrinth by Nick HorvathPlease visithttps://thebookvoice.com/podcasts/2/audible/44153to listen full audiobooks.
Title: Sledge vs. The Labyrinth
Author: Nick Horvath
Narrator: Joshua Saxon
Format: mp3
Length: 8 hrs and 3 mins
Release date: 05-01-25
Ratings: 5 out of 5 stars, 3 ratings
Genres: Mystery
Publisher's Summary:
When his former lover, Kiira, finds herself the target of a mysterious dark web assassin network, modern-day gladiator, Einarr “Sledge” Laukkanen, embarks on a blood-spattered mission to uncover who lurks at its heart. But as he bludgeons his way down to its lowest depths, one thing becomes terrifyingly clear: NO ONE ESCAPES THE LABYRINTH . . . "A NEW ACTION ICON." – Steve Stark, auther...
2025-05-018h 03
Commercial Real Estate Insights PodcastGasworx Progress, Ybor City vs. Kitchener, and 2024 CRE Lending TrendsIn this episode, Steve Hamoen begins with an introduction before providing an overview of the Gasworx and La Union Apartments, detailing their progress. He then compares the real estate landscapes of Ybor City and Kitchener-Waterloo, highlighting key differences and similarities. The episode continues with a look at Colliers' expansion in San Francisco's retail real estate sector and a discussion on Horvath & Tremblay's recent retail transaction in Providence. Steve also offers insights into the commercial property insurance market with expertise from Risk Strategies Co. Finally, he examines trends in commercial real estate lending anticipated for 2024, wrapping up with closing remarks and...
2025-04-2609 min
HOA Insights: Common Sense for Common Areas101 | Turning HOA Struggles Into Strength and TrustSend us a textLearn from special guest Steve Horvath how to build trust, improve communication, and lead your HOA with strength and transparency!✅ Is a Reserve Study right for you? 👉 https://www.reservestudy.com/Robert Nordlund welcomes longtime homeowner advocate Steve Horvath to share hard-won wisdom from the boardroom. Steve, co-founder of HOA United, unpacks how board members can go beyond the bare minimum and truly advocate for their communities. They explore why open meetings matter, how to ask better questions, and why blind trust in experts can lead to costly mistakes.S...
2025-04-1432 min
The Daily MotivationCell Reprogramming - The Future of Aging Reversal | Dr. Rhonda Patrick EP 920Don't miss the Make Money Easy Book Tour! https://lewishowes.com/moneyyouCheck out the full episode: greatness.lnk.to/1742"The epigenome resets completely and there's no sign of aging. It's kind of fascinating...I think that we might have a tuneup where we go and get rejuvenated." - Dr. Rhonda PatrickImagine a future where we could reset our biological clock, turning back aging at the cellular level. Dr. Rhonda Patrick takes us on a mind-blowing journey through cutting-edge longevity research, explaining how scientists have discovered ways to reprogram old cells into youthful...
2025-03-1506 min
Milieu oder Mikrobe#086: Neues von Omega-3 – wie Du Deine epigenetische Uhr bremst!Interessante neue Studie demonstriert: Omega-3 bremst Deine innere Uhr und verlängert das Leben!
Die Omega-3 Produkte dieser Firmen können wir empfehlen:
NORSAN
Mit dem Code EM322 bekommt Ihr 15% Rabatt auf Eure erste Bestellung.
NATUGENA
Mit dem Code 13197 bekommt Ihr 10 EUR Rabatt auf Eure erste Bestellung bei NatuGena.
Die erwähnte Kölner Liste, auf der Ihr viele Supplemente findet.
Bei der Studie zur Fibromyalgie haben wir die Visuelle Analog Skala erwähnt. Unter dem Link gibt es weitere Infos. Weiterhin haben wir noch mehrere Schmerzskalen angesprochen:
Den Wides...
2025-03-0354 min
NZZ AkzentWie ein Forscher das Altern stoppen will
Die epigenetische Uhr ist heute nicht mehr aus der Altersforschung wegzudenken. Bei einem Selbstversuch stiess der Entdecker Steve Horvath auf eine Überraschung: Seine Zellen waren deutlich älter als diejenigen seines Zwillingsbruders.
Heutiger Gast: Stephanie Lahrtz, Wissenschaftsredaktorin
Host: Antonia Moser
Weitere Informationen zum Thema: https://www.nzz.ch/wissenschaft/die-epigenetische-uhr-gibt-unser-wahres-alter-an-wie-erfinder-steve-horvath-tickt-ld.1778684
Informiere dich kurz, kompakt und fokussiert über das Weltgeschehen mit unserem täglichen Newsletter, dem «NZZ Briefing». Jetzt kostenlos registrieren und abonnieren unter go.nzz.ch/briefing
2025-02-1117 min
Basel am BallBasel am Ball #12 mit Steve Beutler, Sportamt Basel-StadtDer Podcast der Host City Basel
Steve Beutler ist Leiter des Sportamtes Basel-Stadt und verantwortlich für die Legacy der UEFA Womens Euro 2025 in Basel.
Was das Grossereignis für ihn als Sportamtsleiter bedeutet und welche Projekte und Angebote er zur Förderung des Frauen- und Mädchenfussballs einbringt, hört ihr in dieser Folge.
🎤Sabine Horvath, Projektleiterin UEFA Women's Euro 2025 Basel
🎤Steve Beutler, Sportamt Basel-Stadt
2025-01-2317 min
Narwhal Capital: After the BellBeyond the Portfolio: Steve HorvathSteve Horvath is a former senior tech fellow at Lockheed Martin. Steve graduated from Georgia Tech with an engineering degree and spent his whole career with Lockheed. In this interview, Steve offers insight into why he stayed at Lockheed, what led to his success at the company, some leaders that he admired during that time, and his financial advice to younger listeners.For information on how to join the Zoom calls live each morning at 8:30 EST, visithttps://www.narwhal.com/blog/daily-market-briefingsPlease see disclosures:https://www.narwhal.com/disclosure
2025-01-2244 min
Own Your Heart Health with Dr. Regina DruzAm I a Ticking Time Bomb? Bio-age Revealed!“If we truly want to focus on preventative medicine and address the biggest risk factor, that risk factor is the biological aging process,” says Ryan Smith, the co-founder of TruDiagnostic, a company at the forefront of epigenetic testing. In this episode, he joins Dr. Regina Druz to break down how advanced tools like DNA methylation clocks are redefining what we know about aging and health.
Is your body aging at the same rate as your chronological years? Ryan explains why that might not be the case and how TruDiagnostic’s DNA methylation technology offers a clearer...
2024-12-1255 min
Health Longevity SecretsWhat is biological vs chronological age?How young are we really, on a cellular level? This week we are joined by Chris Mirabile, a brain tumor survivor and the visionary CEO of Novos, shares his journey of significantly reducing his biological age. In full disclosure, I am a scientific advisor to NOVOS but I only affiliate with those companies that I believe in. Chris discusses the difference between chronological and biological age and learn how advanced epigenetic tests can offer insights into your health and longevity. We go through the evolution of epigenetic clocks, from Steve Horvath's groundbreaking research to the sophisticated tools we have t...
2024-10-2931 minHealth Longevity SecretsLongevity SecretsThis week we uncover the secret to a longer, healthier life as we sit down with Dr Buck Joffrey, a former neurosurgery and otolaryngology resident turned cosmetic surgeon and serial entrepreneur. Buck’s journey from the operating room to the forefront of longevity science was ignited by a personal health scare and fueled by the pioneering work of David Sinclair. Join us as Buck shares his transformative story, emphasizing the profound impact of lifestyle changes like diet, exercise, and sleep on extending our lifespans, and even hints at the tantalizing possibility of age reversal.Explore the groundbreaking sc...
2024-10-1544 min
American Alchemy with Jesse MichelsThe “Clock” That Can Predict Death | Dr. Steve HorvathSteve Horvath is a German–American aging researcher, geneticist, and biostatistician. He is a professor at the University of California Los Angeles known for developing the Horvath aging clock, which is a highly accurate molecular biomarker of aging. Having a clock that’s able to predict age is incredibly important for longevity research and begets important philosophical questions that we discuss in this episode. Please enjoy this conversation with Dr. Steve Horvath.*** AMERICAN ALCHEMY is an original series hosted by Jesse Michels that explores the frontier of science and tech. Each week, we bring you...
2024-10-0520 min
College Gridiron Coast To CoastYards And Stripes | The Daily and Horvath ShowThis week, hosts Price Atkinson and Steve Carney break down the latest games and news from Army, Navy, and Air Force. Despite the looming threat of Hurricane Helena, the duo brings you an action-packed episode filled with game analysis, conference realignment updates, and much more. Army continues its winning streak, Navy secures a monumental victory, and Air Force looks to bounce back. Tune in for all the excitement and expert insights!This episode is sponsored in part by TicketSmarter:Use promo code LWOS10 to receive $10 off purchases of $100 or moreUse promo code LWOS20...
2024-09-2749 minCollege Gridiron Coast To CoastYards And Stripes | The Daily and Horvath ShowThis week, hosts Price Atkinson and Steve Carney break down the latest games and news from Army, Navy, and Air Force. Despite the looming threat of Hurricane Helena, the duo brings you an action-packed episode filled with game analysis, conference realignment updates, and much more. Army continues its winning streak, Navy secures a monumental victory, and Air Force looks to bounce back. Tune in for all the excitement and expert insights!This episode is sponsored in part by TicketSmarter:Use promo code LWOS10 to receive $10 off purchases of $100 or moreUse promo code LWOS20...
2024-09-2749 min
DecentraLoungeS02 - E19 - Steve Horvath VP of Sales at ForDefiGlobalStake‘s recent S02 E19 recent S02 E19 #DecentraLounge episode with Steve Horvath the VP of Sales at FORDEFI 🚀 In this episode Steve outlines: 1️⃣ What is ForDefi and How is It Unique for Institutions 2️⃣ Purpose Built FOR DeFi Transactions (Including Accurate Reporting) 3️⃣ Security (Insurance & SOC2 Type II) 4️⃣ Who Are the […]
The post S02 – E19 – Steve Horvath VP of Sales at ForDefi appeared first on DecentraLounge.
2024-09-0325 minDecentraLoungeS02 - E19 - Steve Horvath VP of Sales at ForDefiGlobalStake‘s recent S02 E19 recent S02 E19 #DecentraLounge episode with Steve Horvath the VP of Sales at FORDEFI 🚀 In this episode Steve outlines: 1️⃣ What is ForDefi and How is It Unique for Institutions 2️⃣ Purpose Built FOR DeFi Transactions (Including Accurate Reporting) 3️⃣ Security (Insurance & SOC2 Type II) 4️⃣ Who Are the […]
The post S02 – E19 – Steve Horvath VP of Sales at ForDefi appeared first on DecentraLounge.
2024-09-0325 min
The Re-engineered You177 - You vs Your Genetics Part 2Can you change your genetics through diet and discipline? What about your stress level? Your IQ? Your earning potential?
In this episode we continue our talk about the field epigenetics, and attempt to bust the top three claims being made by epigenetic researchers. Health, wealth, and longevity are supposedly malleable and changeable, to a degree, thanks to practices that reverse DNA methylation (aging). But how firm is the science of changing our bodies and minds? Are there any proven cases of people living longer, thanks to adopting a DNA-friendly diet? Or is this another case of self-help...
2024-08-2800 minMilieu oder Mikrobe#059: Länger leben, besser leben - Longevity, der Weg für ein gesundes AlternStrategien für ein längeres Leben
Alle Infos zu Prof. Dr. med. Kleine-Gunk
Die German Society of Anti-Aging Medicine. Alle Infos dazu, findet ihr hier.
Das Metropol Medical Center-Nürnberg. Auch hier ist Prof. Kleine-Gunk zu finden.
Der im Podcast erwähnte Steve Horvath und die Epigenetische Uhr
Was ist die epigenetische Uhr - Antworten vom Max-Plack-Institut für Biologie des Alterns
Wer mehr Infos zu dem erwähnten Tech-Milliardär Bryan Johnson erfahren möchte, startet hier
Wenn jemand näher in das Thema eintauchen möchte. H...
2024-08-2659 min
Ground TruthsSteve Horvath: Our Epigenetic Age ClocksSteve Horvath made the seminal discovery of the—Horvath Clock— an epigenetic clock based on DNA methylation, which is now being used extensively in medical research and offered commercially for individuals (←we talk about that!). He was on the faculty at UCLA from 2000-2022 as a Professor of Human Genetics and Biostatistics, and now works on anti-aging research at Altos Labs.A perspective on the importance of epigenetic clocks this week’s Nature”This insight is crucial for deriving reliable biological markers of ageing in tissues or blood. Such a feat has been accomplished through the ingenious identifica...
2024-08-2341 min
Aging-USCo-analysis of Methylation Platforms for Signatures of Biological Aging in the Domestic DogBUFFALO, NY- July 23, 2024 – A new #research paper was #published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 13, entitled, “Co-analysis of methylation platforms for signatures of biological aging in the domestic dog reveals previously unexplored confounding factors.”
Chronological age reveals the number of years an individual has lived since birth. By contrast, biological age varies between individuals of the same chronological age at a rate reflective of physiological decline. Differing rates of physiological decline are related to longevity and result from genetics, environment, behavior, and disease. The creation of methylation biological age pr...
2024-07-2303 min
Aging-USDepression, Antidepressants, Epigenetic Age Acceleration, and Mortality in Postmenopausal WomenBUFFALO, NY- June 10, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 10, entitled, “Relationships of depression and antidepressant use with epigenetic age acceleration and all-cause mortality among postmenopausal women.”
In this new study, researchers May A. Beydoun, Hind A. Beydoun, Jason Ashe, Michael F. Georgescu, Steve Horvath, Ake Lu, Anthony S. Zannas, Aladdin H. Shadyab, Su Yon Jung, Sylvia Wassertheil-Smoller, Ramon Casanova, Alan B. Zonderman, and Robert L. Brunner from the National Institute on Aging, U.S. Department of Veterans Affairs (Washington, DC), University of Texas...
2024-06-1004 min
Aging-USAging Contributes to 2024 Systems Aging Gordon Research ConferenceBUFFALO, NY- May 20, 2024 – Aging is a contributor at the 2024 Systems Aging Gordon Research Conference (GRC) on “Systems Modeling, Aging Biomarkers, and Longevity Interventions” — taking place from June 2–7, 2024, in Castelldefels, Barcelona, Spain.
“The conference will present recent advances in systemic rejuvenation, multi-omics approaches, applications of machine learning/artificial intelligence, and approaches for enhancing the chance of successfully translating basic research results to the clinic.” – GRC.org
Additionally, many Aging authors have been invited to speak and lead discussions at the 2024 Systems Aging GRC. Among them are distinguished members of Aging’s Editorial Board, including Steve Horvath, David Sinclair, Vera Gorbunova, Vadim Gladyshev, Guido K...
2024-05-2002 min
Age Less / Live MoreMethylation, Epigenetics & Longevity with Steve HorvathKane Tanaka of Japan died in 2022 at the age of 119. Lucile Randon of France died in 2023 at 118. Jiroemon Kimura of Japan died in 2023 at 116, the oldest male ever. What did these people have in common? Were they biohackers? Did they do CrossFit? Did they take NAD supplements or run marathons? Nope. Like almost all centenarians they lived exceptionally long lives most-likely due to genetics, combined with a moderately healthy or even average healthy lifestyle. Despite the overwhelming abundance of evidence that we're all going die sooner rather than later, the quest for longevity never stops. My guest on this...
2024-05-0145 minMilieu oder Mikrobe#034: Longevity - Entdecke die Geheimnisse der LanglebigkeitGesund alt werden: Praktische Strategien für ein gesundes und erfülltes Leben bis ins hohe Alter!
Artikel der Süddeutschen Zeitung zur Lebenserwartung
Der erwähnte Nobelpreisträger Shin’ya_Yamanaka
Ein aktueller Artikel aus der neuen Zürcher Zeitung zu Alterungsprozessen
Steve Horvath und die Epigenetische Uhr
Was ist die epigenetische Uhr - Antworten vom Max-Plack-Institut für Biologie des Alterns
Europaweit erste Ausbildung zum zertifizierten und ärztlich geprüften
LONGEVITY-TRANSFORMATIONS-COACH
Kontakt zu uns:
info@milieu-oder-mikrobe.de
Dr. FREESE AKADEMIE WEBSITE
Dr. FR...
2024-03-0442 min
Aging-USAging’s Top 10 Papers in 2023 (Crossref Data)Crossref is a non-profit organization that logs and updates citations for scientific publications. Each month, Crossref identifies a list of the most popular Aging (Aging-US) papers based on the number of times a DOI is successfully resolved.
Below are Crossref’s Top 10 Aging DOIs in 2023.
10: Old-age-induced obesity reversed by a methionine-deficient diet or oral administration of recombinant methioninase-producing Escherichia coli in C57BL/6 mice
DOI: https://doi.org/10.18632/aging.204783
Authors: Yutaro Kubota, Qinghong Han, Jose Reynoso, Yusuke Aoki, Noriyuki Masaki, Koya Obara, Kazuyuki Hamada, Michael Bouvet, Takuya Tsunoda, and Robert M. Hoffman
9: Metformin use history and genome-wide DNA methylation profile: po...
2024-02-1507 min
Biohacking Girls - Din podcast for optimal helse200. Biokjemiker Hanne S. Finstad om antialdringsbrytere, metformin, hormese, gener og epigenetikkHva er den ledende årsaken til at vi dør, er det aldring eller er det sykdom?I denne podcasten snakker vi med biokjemiker med en doktorgrad i Omega 3 fettsyrer og forfatter Hanne S. Finstad. Hanne er aktuell med boken "Yngre" der hun inviterer oss inn på sitt selvstudie og foryngeslesreise. Hanne blir i følge flere biologiske alderstester 5 år yngre i løpet av dette året. Du får høre detaljerte beskrivelser om hennes protokoller og utprøving som består av mat, faste, trening, hormetisk stress, medisiner og tilskudd. Det er tydelig at hun er inspirer...
2024-02-121h 06
2024-01-1400 min2024-01-1400 min
Önkényes Mérvadó (Spirit FM)Veszélyben Macron hatalma? ;Hajdu Steve a Reggeliben; Techfeudalizmus – Önkényes Mérvadó 2024#574Önkényes Mérvadó:
00:00 Veszélyben Macron hatalma?
22:29 Hajdu Steve a Reggeliben
47:28 Technofeudalizmus
1:08:54 Technofeudalizmus
Műsorvezetők: Horváth Oszkár, Puzsér Róbert, Boros Tamás
Szerkesztő: Pap Zsófia / Germán Péter
Programigazgató: Korvin Tibor
2024.01.09.
Forrás:
https://rtl.hu/reggeli/2024/01/02/azahriah-szoboszlai-dominik-z-generacio-siker-hajdu-steve
Facebook: https://www.facebook.com/spiritfmbp
Instagram: https://www.instagram.com/spiritfmbp
E-mail: hello@spiritfm.hu
2024-01-101h 30Önkényes Mérvadó (Spirit FM)Veszélyben Macron hatalma? ;Hajdu Steve a Reggeliben; Techfeudalizmus – Önkényes Mérvadó 2024#574Önkényes Mérvadó:
00:00 Veszélyben Macron hatalma?
22:30 Hajdu Steve a Reggeliben
46:11 Techfeudalizmus
1:07:37 Techfeudalizmus
Műsorvezetők: Horváth Oszkár, Puzsér Róbert, Boros Tamás
Szerkesztő: Pap Zsófia / Germán Péter
Programigazgató: Korvin Tibor
2024.01.09.
Facebook: https://www.facebook.com/spiritfmbp
Instagram: https://www.instagram.com/spiritfmbp
E-mail: hello@spiritfm.hu
2024-01-091h 29
Ground TruthsTony Wyss-Coray: The Science of AgingThe science to advance our understanding of the aging process—and to potentially slow it down—has made important strides. One of the leading scientists responsible for this work is Professor Tony Wyss-Coray, whose work has particularly focused on brain aging but has implications for all organs. I believe his December 2023 Nature paper on blood proteins that can track aging for 11 of our organs is one of the most important aging reports yet.Here is the audio and transcript of our conversation, recorded 20 December 2023, with a few relevant external links.This is the last Ground Trut...
2023-12-2632 min
Angel Invest BostonTom Weldon - A Fountain of YouthAging Fit Substack: Learn More Repeat life science entrepreneur Tom Weldon is now taking on aging. He is commercializing a compound to extend health span developed at a prominent institution. Composed of substances generally considered as safe by the FDA, the formula has shown impressive results in mice and, to date, in one human, Tom himself. Intriguing chat with a dynamic founder. Sponsored by Purdue University entrepreneurship and Peter Fasse, patent attorney at Fish and Richardson. Highlights: Sal Daher Introduces Tom Weldon What Problem Rejuvant Addresses "... The...
2023-12-2045 min
London FuturistsLongevity Summit Dublin: four new mini-interviewsThis episode, like the previous one, consists of a number of short interviews recorded at the Longevity Summit Dublin between 17th and 20th August, featuring a variety of different speakers from the Summit.In this episode, we'll hear first from Matt Kaeberlein, the CEO of a company called Optispan, following a 20 year period at the University of Washington studying the biological mechanisms of aging and potential interventions to improve healthspan. Among other topics, Matt talks to us about the Dog Aging Project, the Million-Molecule Project, and whether longevity science is at the beginning of the end or...
2023-09-0645 min
Renee Belz & Lauren SambataroPredict, Measure and Take Action on Your Biological Clock l How to Slow Down the Aging Process with Hannah Went of TruDiagnostic Epigenetic TestingWe’re thrilled to bring you this conversation with Hannah Went all about aging, biological clocks and epigenetics! She brings incredible insight into the options for testing your biological age, thoughts on telomere testing, the biggest drivers of aging, and what we can learn from the Dunedin pace of aging test. Tune in if you’re interested in extending your healthspan! Hannah Went has a lifelong passion for longevity and breakthrough, disruptive technologies that drive radical improvement to the human condition. She attended the University of Kentucky and graduated with a degree in Biology. During that time, she h...
2023-08-211h 09
The Talking Friendship with Mike D PodcastSeason 4 - Episode 2 (PART ONE) - Mike talks his favorite Detroit Pro Sports Athletes from growing up with Todd Pretty, Tim Horvath and Kyle UrekIn Episode 2 (part 1!) of Season 4 Mike welcomes FOUR Of his good friends (S1E1 guest and Movie Crew member Todd Pretty, S1E11 and College Football Preview pod guest Tim Horvath, and S2E9 Guest Kyle Urek for a rollicking discussion of their favorite Detroit pro sports athletes from growing up in Allen Park, MI. In addition, there’s a special added musical gift with each selection you won’t want to miss!Follow the podcast on Twitter: @friendsofmikedEmail the podcast at talkingfriendship@gmail.comKey moments from the pod: 0:30: Mike w...
2023-08-081h 33
Innovation in Compliance with Tom FoxSupply Chain Cyber Risk Management with Steve HorvathImagine a world where your organization is constantly at the risk of a cyber-attack, yet no solution seems fully secure. In this episode of Innovation In Compliance, host Tom Fox and guest Steve Horvath explore the complex landscape of supply chain cyber risk management. They explore the high-profile breaches of Home Depot and Target, as well as the critical importance of frameworks like the NIST Cybersecurity Framework. Steve delves into the challenges faced by organizations, the need for effective risk management strategies, and the evolving landscape of cybersecurity in public and private sectors. Steve H...
2023-06-2725 min
Mind Pump: Raw Fitness Truth2102: Maximizing Athletic & Cognitive Performance With Dr. Stephen CabralIn this episode Sal, Adam & Justin speak with Dr. Stephen Cabral about how to achieve high performance health. What is High-Performance Health? (2:20) The main parameters that most longevity scientists look at to measure biological age. (5:47) The correlation between internal biological and external age. (11:28) Can hormone therapy reverse biological age alone? (18:33) The impact that sleep has on your biological age. (21:56) Should we sleep more in the winter and less in the summer? (26:24) How to track the stages of sleep. (27:23) Ways to improve REM and d...
2023-06-221h 11
Aging-USDNAmFitAge: Biological Age Indicator Incorporating Physical FitnessA new research paper was published in Aging (Aging-US) Volume 15, Issue 10, entitled, “DNAmFitAge: biological age indicator incorporating physical fitness.”
Physical fitness is a well-known correlate of health and the aging process and DNA methylation (DNAm) data can capture aging via epigenetic clocks. However, current epigenetic clocks did not yet use measures of mobility, strength, lung, or endurance fitness in their construction.
In this new study, researchers develop blood-based DNAm biomarkers for fitness parameters including gait speed (walking speed), maximum handgrip strength, forced expiratory volume in one second (FEV1), and maximal oxygen uptake (VO2max) which have modest correlation with fitness para...
2023-06-0703 min
Everything EpigeneticsHuman Skeletal Muscle Epigenetic Clock Explained with Dr. Sarah VoisinMaintaining muscle mass is crucial for healthy aging, as it is closely linked to overall physical function and quality of life. As we age, our bodies naturally experience a decline in muscle mass and strength, known as sarcopenia. This loss of muscle mass can lead to a range of negative health outcomes, including decreased mobility, increased risk of falls and fractures, and decreased metabolic rate. Additionally, loss of muscle mass can contribute to chronic conditions such as obesity, diabetes, and cardiovascular disease. By developing an epigenetic clock for skeletal muscle, Dr. Voisin and her colleagues have identified...
2023-04-2635 min
What a WasteComedy and Wildlife Conservation with Eeland StriblingOn this week’s episode, we welcome Black Steve Irwin himself, Eeland Stribling! Eeland is a hilarious Denver-based comedian, wildlife educator and biologist, and arguably the most famous comedian fly fisher in the world/all of human existence. Eeland joins Lucia and Tyler to talk about using comedy as a tool to talk about conservation issues, his work as a wildlife technician, his love of fly fishing, and why the water is better than space. He also helps Lucia work through her deep, karmic fear of fish and crabs. Follow Eeland on Instagram and Tik Tok, and check out hi...
2023-03-1440 min
The Power of GeneticsDiscovering the Potential of Epigenetics with Entrepreneur Scientist Ryan Smith
In this episode of the Power of Genetics podcast, Ryan Smith shares his journey as an entrepreneur and scientist in the fields of epigenetics and diagnostics. He discusses the importance of maintaining scientific integrity and finding something you're passionate about in order to truly succeed in any field.
Ryan shares his insights on the potential of epigenetics in predicting a variety of outcomes related to age and chronic diseases. He highlights the importance of tracking outcomes and using data to prove the efficacy of treatments, which can be challenging in a field that is constantly evolving and su...
2023-02-2332 min
Aging-USAging’s Top 10 Papers In 2022 (Crossref Data)Crossref is a non-profit organization that logs and updates citations for scientific publications. Below are Crossref’s Top 10 Aging DOIs in 2022.
10: DNA- and telomere-damage does not limit lifespan: evidence from rapamycin
DOI: https://doi.org/10.18632/aging.202674
Author: Mikhail V. Blagosklonny
9: Psychological factors substantially contribute to biological aging: evidence from the aging rate in Chinese older adults
DOI: https://doi.org/10.18632/aging.204264
Authors: Fedor Galkin, Kirill Kochetov, Diana Koldasbayeva, Manuel Faria, Helene H. Fung, Amber X. Chen, and Alex Zhavoronkov
8: DNA methylation GrimAge strongly predicts lifespan and healthspan
DOI: https://doi.org/10.18632/aging.101684
Authors: Ake T. Lu, Austin Quach, James G. Wi...
2023-02-2107 min
Aging-USDNA Methylation GrimAge Version 2A new research paper was published in Aging (listed as “Aging (Albany NY)” by MEDLINE/PubMed and “Aging-US” by Web of Science) Volume 14, Issue 23, entitled, “DNA methylation GrimAge version 2.”
Researchers Ake T. Lu, Alexandra M. Binder, Joshua Zhang, Qi Yan, Alex P. Reiner, Simon R. Cox, Janie Corley, Sarah E. Harris, Pei-Lun Kuo, Ann Z. Moore, Stefania Bandinelli, James D. Stewart, Cuicui Wang, Elissa J. Hamlat, Elissa S. Epel, Joel D. Schwartz, Eric A. Whitsel, Adolfo Correa, Luigi Ferrucci, Riccardo E. Marioni, and Steve Horvath from the University of California Los Angeles, Altos Labs, University of Hawaii at Manoa, Fred Hutchinson C...
2022-12-2103 min
Foreigner FootballUSMNT Roster Talk with Steve Dosskey! + Preview of USA's Three World Cup Group Stage Games!Nolan, Joe, and special guest, Steve Dosskey break down the 26-man USMNT World Cup roster that head coach Gregg Berhalter released on Wednesday. They also preview each of the USA's group stage games against Wales, England, and Iran.
Join the Foreigner Football Fantasy League!
https://fantasy.premierleague.com/leagues/auto-join/xhipa9\
Follow us on Twitter! @ForeignerFooty
Episode 5 Clip Credit:
Ethan Horvath Nations League save: @CBSSportsGolazo
Shaq Moore goal vs Canada: @FOXSoccer
Kellyn Acosta Gold Cup assist: @FOXSoccer
Berhalter on Haji Wright: @USMNTvsHaters
Brandon Vasquez goal: @fccincinnati
Clint Dempsey goal vs En...
2022-11-151h 03
Aging-USLongevity & Aging Series (EP 3): Dr. Steve Horvath - Epigenetic ClocksIn the third episode of the Longevity & Aging Series, Dr. Steve Horvath, Professor of Human Genetics and Biostatistics at UCLA, and Principal Investigator at Altos Labs, discusses the evolution of aging research and epigenetic clocks with host Brian Chen.
Special Collection on Steve Horvath's Publications in Aging - https://www.aging-us.com/special-collections-archive/steve-horvath
Author contact - Steve Horvath - shorvath@mednet.ucla.edu
Longevity & Aging Series - https://www.aging-us.com/longevity
Transcript - https://aging-us.net/2022/08/23/longevity-aging-series-ep-3-dr-steve-horvath-epigenetic-clocks/
About Aging-US
Launched in 2009, Aging-US publishes papers of general interest and biological significance in all fields of aging research and...
2022-08-2323 min
Aging-USLongevity & Aging Series (EP 2): Dr. Steve Horvath's Special Collection in AgingIn the second installment of the Longevity & Aging Series, Dr. Steve Horvath, a world-renowned researcher, geneticist, biostatistician, Professor of Human Genetics and Biostatistics at the University of California, and Principal Investigator at Altos Labs, revisits 29 papers he co-authored that were published by Aging (Aging-US) and featured as a special collection of his research.
Special Collection - https://www.aging-us.com/special-collections-archive/steve-horvath
Author contact - Steve Horvath - shorvath@mednet.ucla.edu
About Aging-US
Launched in 2009, Aging-US publishes papers of general interest and biological significance in all fields of aging research and age-related diseases, including cancer—and now, with a sp...
2022-08-041h 12
PNAS Science SessionsEpigenetic clocks for humans and dogsSteve Horvath and Elaine Ostrander explain the usefulness of epigenetic clocks in humans and dogs.
2022-07-1813 min
Docus Audio LatinoEn busca de la inmortalidadDescifrar el código secreto del envejecimiento
¿Se puede revertir o incluso eliminar el envejecimiento? Si logramos desentrañar este secreto de la biología humana, en poco tiempo, podríamos vencer enfermedades relacionadas como el cáncer, la demencia y problemas cardíacos.
La carrera por inventar la píldora mágica ya está en marcha. Científicos de todo el mundo se están acercando de forma sorprendente al deseo ancestral de la humanidad: ser inmortal.
La pugna cobró impulso con el descubrimiento de Luis Rosero Bixby de la "zona azul” de Costa Rica. En la península de Nicoya llama...
2022-07-1251 minAging-USAnnouncement: Sponsoring Systems Aging Gordon Research ConferenceBUFFALO, NY- May 24, 2022 – Aging (Aging-US) is sponsoring the Systems Aging Gordon Research Conference, “Systemic Processes, Omics Approaches and Biomarkers in Aging,” from May 29 to June 3, 2022, at the Grand Summit Hotel at Sunday River in Newry, Maine, USA.
This year, the Chair and Vice Chair of the conference are Aging Editorial Board members Vadim N. Gladyshev, Professor of Medicine at Harvard Medical School and Director of Redox Medicine at Brigham and Women’s Hospital, and Steve Horvath, Professor of Human Genetics and Biostatistics at the University of California, Los Angeles. Dr. Gladyshev is known for his characterization of the human selenoproteome. He was a...
2022-05-2503 min
FoundMyFitness#072 Morgan Levine, PhD, on PhenoAge and the Epigenetics of Age Acceleration — can we change the pace?Morgan Levine, Ph.D., developed the phenotypic aging clock called PhenoAge and is a Founding Principal Investigator at Altos Labs, a biotech company that seeks to understand the mechanisms that drive the aging process and age-related diseases with the hope of identifying possible interventions. Additionally, Dr. Levine is an assistant professor of pathology at the Yale University School of Medicine, where her research focuses on the science of biological aging. Dr. Levine completed a postdoctoral fellowship with previous guest Dr. Steve Horvath, a pioneer in the field of epigenetic clocks. In this episode, Dr. Levine a...
2022-04-121h 29
THE ONE'S CHANGING THE WORLD -PODCASTBREAKTHROUGH IN AGE REVERSAL WITH YOUNGBLOOD PLASMA - DR HAROLD KATCHER - CTO NUGENICS RESEARCH#nugencis #nugenicsresearch #humanlongevity #agereversal #blissatomic
Dr. Harold has been a pioneer in the field of cancer research, in the development of modern aspects of gene hunting and sequencing. He carries expertise in bioinformatics, chronobiology, and biotechnology and is currently working in the capacity of Chief Technical Officer at Nugenics Research Pvt Ltd. exploring in anti-aging modalities. They recently released a paper online on #biorxiv regarding their breakthrough research on Human Age Reversal using Young Blood #plasma, the paper’s authors include recognized Longevity academician Steve Horvath.
The paper also caught the attention of #davidsinclair the le...
2022-04-1131 min
Aging-USAnnouncement: Special Collection of Dr. Steve Horvath Publications in AgingListen to a blog summary of the announcement for a special collection of Steve Horvath research papers published by Aging (Aging-US).
____________________
Epigenetics is the study of gene expression and the changes that occur which do not involve alterations in the DNA sequence. These changes can occur as a result of environmental influences, including exposure to chemicals, diet and stress. Epigenetic modifications can be passed down through generations and play an important role in disease development. An exciting area of epigenetics research is its role in the aging process. Studies have shown that epigenetic modifications can affect aging and the onset...
2022-03-3105 min
The Morning Market BriefingBeyond the Portfolio: Steve HorvathSteve Horvath is a former senior tech fellow at Lockheed Martin. Steve graduated from Georgia Tech with an engineering degree and spent his whole career with Lockheed. In this interview, Steve offers insight into why he stayed at Lockheed, what led to his success at the company, some leaders that he admired during that time, and his financial advice to younger listeners.
2022-03-2544 min
Power Monday PodcastPMP #70 - Per què envellim i com aturar l'envellimentQuants anys t’agradaria viure? Tagradaria 80? 100? 120? T’agradaria viure per sempre?
La teva resposta pot canviar si afegeixo un matís: I si aquests anys els visquessis, amb bona salut, amb bones relacions i feliç? Llavors voldires viure més?
En general tots, aquells que tenen salut, un propòsit i estan contents de viure volen viure més. Ningú feliç i saludable vol morir.el problema amb envellir és que sovint significa tornar-se més fràgil i malalt crònic, però això no té per què ser així. En aquest episodi, comparteixo amb tu tot el que he aprè...
2022-03-1446 min
The Doctor's Kitchen Podcast#138 Why We Will Live Past 200 years with Sergey YoungI am fascinated with the science of longevity and I think this is probably the most disruptive area of science and technology that will have huge implications for not only health but also drastically impact culture, society and the planet.We’ve spoken to longevity researchers in the field, but today I wanted to open up the conversation to the drivers of this research area.Sergey Young is a longevity investor and visionary with a mission to extend the healthy lifespans of one billion people. To do that, Sergey founded the Longevity Vision Fund ...
2022-02-231h 04
PortfolioHorváth András: Elon Musk nem Steve Jobs, a Tesla nem az AppleHorváth Andrást rengetegen követik a YouTube-on, ami azt jelzi, hogy hatalmas érdeklődés van az elektromos autókra, hiszen a csatornáján elsősorban erről van szó. Bár véleménye megosztó és bejegyzéseivel, kommentjeivel nagy vihart kavart a villanyautós közösségben az utóbbi időszakban, érdemes őt meghallgatni, mert talán ő az az ember Magyarországon, aki a legtöbb belső égésű motor nélküli járművet próbálhatta ki itthon. A Tesla technológiai és versenyelőnyével kapcsolatban erősen szkeptikus, ugyanakkor a német prémiummárkák, vagy a Hyun...
2022-01-1752 min
Aging-USEpigenetic Age of the Pre-frontal CortexAging-US published "Epigenetic age of the pre-frontal cortex is associated with neuritic plaques, amyloid load, and Alzheimer’s disease related cognitive functioning" in 2015, which reported that there is an urgent need to develop molecular biomarkers of brain age in order to advance our understanding of age related neurodegeneration.
Here the authors use n=700 dorsolateral prefrontal cortex samples from Caucasian subjects of the Religious Order Study and the Rush Memory and Aging Project to examine the association between epigenetic age and Alzheimer’s disease related cognitive decline, and AD related neuropathological markers.
The neuropathological markers may mediate the association between epigenetic age...
2022-01-0404 min
What's Next｜科技早知道S5E29｜重金押注抗衰老公司，硅谷真的可以做出长生不老药吗？2021 年 9 月 4 日，《麻省理工科技评论》发布报道，称亚马逊创始人 Jeff Bezos 和硅谷著名投资人 Yuri Milner 在近期投资了专注于抗衰方向的生物科技公司 Altos Labs，一家今年四月才成立的抗衰老公司，科学家团队包括 2012 年诺贝尔生理学或医学奖的获得者山中伸弥；截至今年六月，该公司已经吸引了至少 2.7 亿美元的投资。这并非硅谷富豪们第一次入局抗衰领域。
2018 年， Jeff Bezos 和 PayPal 联合创始人 Peter Thiel 共同投资抗衰领域独角兽 Unity Biotechnology；而更早之前，还有谷歌创始人 Larry Page 宣布 10 亿美元投资生物科技公司 Calico，目前 Calico 已经被整合至谷歌母公司 Alphabet Inc。我们似乎可以清晰地看见，在颠覆互联网、物流制造、航空航天等领域之后，硅谷大佬们的下一个目标，正是通过生物工程技术突破人类目前的寿命上限，将长生不老的选择权紧紧握在手里。
本期节目，我们邀请到了同样在抗衰领域被视为明星公司的硅谷新贵 Gordian 的首席科学家 Martin Borch Jensen。他和主播 Diane 一起探讨了硅谷的投资者们都是出于什么原因投资 Altos Labs 等生物科技公司，值得关注技术路径有哪些，投资人应该如何看待生物科技领域的超长投资周期和技术挑战，头部公司可以通过什么途径实现商业回报。
#加入我们#
声动活泼正在招聘「内容研究员」、「业务拓展和合作管理总监/经理」、「声音设计师」、「播客制作实习生」、「内容营销负责人」及「节目制作人」，查看详细讯息请在公号「声动活泼」回复暗号：入场券 。简历接收邮箱📮 hr@shengfm.cn 。
▼主播
丁教，声动活泼联合创始人
▼嘉宾
Martin Borch Jensen，Gordian 首席科学家
▼主要话题
[02:24] 本期节目的亮点总结
[09:03] Gordian 是什么样的生物科技公司？
[10:30] 大牛辈出的巴克研究所在抗衰科研领域是什么样的存在？抗衰领域的生物科技初创公司应该选择在西海岸还是东海岸？
[14:34] 为什么抗衰领域会引来硅谷富豪的投资热潮？
[17:53] Elysium 推出的膳食补充剂 Basis 真的可以抗衰吗？
[19:50] 抗衰的主流技术路径都有哪些？
[27:03] 像 BioViVa 的 CEO 给自己注射抗衰药物的事情常见吗？
[27:57] 除了富豪们的家族信托基金，还有哪些投资机构关注这个赛道？什么时候看见回报？
[30:55] 抗衰公司为什么在二级市场不吃香？临床实验失败有多常见？
[35:30] 如何理解 Gordian 这样的平台型公司的商业模式？谷歌麾下的 Calico 值得期待吗？
[40:58] 抗衰领域在面临哪些挑战？衰老标志物会如何促进抗衰研究的发展？抗衰进程已经走到哪一步了？
[48:30] 有什么人人皆可尝试的长寿小秘诀？
▼延伸阅读
Meet Altos Labs, Silicon Valley’s latest wild bet on living forever
Mutation Doubles Life Span In Worms
A month after losing its lead program, Unity Biotechnology cuts 30% of staff in restructuring
雷帕霉素（ Rapamycin, RAPA ）：一种临床使用的免疫抑制剂，常用于肾移植抗排异治疗和肾癌治疗；1994 年发现抑制雷帕霉素靶点（Mechanistic Target of Rapamycin，mTOR）可调控细胞的存活，2009 年被证明可用于肝硬化及肝功能退化、阿尔茨海默症等并重的治疗，现为主流的长寿药之一
靶向清除衰老细胞的药物（ Senolytics ）：尚无正式的中文译名，2015 年在《 Aging Cells 》上首次出现，由 CAR-T 细胞改造为可定向清除衰老细胞的小分子药剂，其中达沙替尼+槲皮素（ Dasatinib plus Quercetin, D+Q ）的联合用药在 2018 年的小鼠实验中被证明可以成功清除衰老细胞，Unity Biotechnology 的 Judith Campisi 设计出 Senolytics 药剂 UBX0101，尚未通过 II 期临床试验
二甲双胍靶向治疗衰老（ Targeting Aging with Metformin，TAME ）：二甲双胍在1922年首次被人工合成，常见于糖尿病治疗和预防，后被发现可用于延缓衰老，抗衰机制包括通过代谢途径激活AMPK（一种蛋白质激酶，可调控能量平衡）、通过抗氧化途径抑制线粒体I型复合体电子传递系统
重编程技术：被认为是逆转衰老的重要手段之一，可通过诱导性多能干细胞（ Induced pluripotent stem cell，iPS ）的技术对细胞进行重新编程，清除细胞的表观遗传记忆并让细胞变得年轻，但也有实验证明该技术可能加速癌症并发
巴克衰老研究所（ Buck Institute for Research on aging ）：非盈利的独立生物医学研究所，1999年成立，是全世界第一个专注于衰老领域的研究所，2018 年与 Insilico、Juvenescence 联合创立 Napa Therapeutics，推进 NAD+ 抗衰药物研发，该研究所也是世界上第一家研究衰老干预过程的研究所，Unity Biotechlogy 的联合创始人 Judith Campisi 目前仍在该所任职
Gordian：抗衰老领域的创新药服务商，2018 年成立，投资方包括 The Longevity Fund、Formic Ventures、谷歌 AI 负责人 Jeff Dean，主要为抗衰领域药企的研发和实验提供测试平台和量化模型，可比公司包括 Genentech、Atomwise
Atomwise：AI 医疗公司，通过 AI 进行药物设计并销售相关药品给厂商，并对药物的收入按一定比例收取佣金，类似的公司还有 Exscientia、InSilico Medicine
Genentech：中文译名基因泰克，起家于 DNA 重组技术的生物科技公司，1976 年由诺奖获得者 Herbert Boyer 联合风险投资人 Kleiner Perkins 创立，1980 年在纳斯达克上市，代表产品包括 Avastin 抗癌药物，与 Gordian 的商业模式类似，2009 年被瑞士罗氏制药公司以468亿美元的价格收购
Elysium Health：膳食补充剂公司，2014 年成立，科学家顾问团包括神经生理学家 Thomas C. Südhof 等多位诺奖得主，代表产品包括 NAD+ 类保健品 Basis（主要成分为烟酰胺核糖和紫檀芪），该产品未经过FDA的药品审批程序，类似的 NMN 产品在国内也未获得监管的生产批准许可
Altos Labs：专注于干细胞重编程的抗衰生物技术公司，2021 年成立，2021 年诺贝尔生理学或医学奖的获得者山中伸弥和甲基化生理年龄时钟之父 Steve Horvath 均为科学顾问委员会成员，贝佐斯投资标的之一，类似的技术方向还有AgeX等主
2021-10-2053 min
Sandy K Nutrition - Health & Lifestyle QueenEpisode 78 How Fast is Your Body Aging? All About Biological Age with Dr. Keith BooherSend me a text! I'd LOVE to hear your feedback on this episode!Exciting announcement: I will be giving away a biological DNA kit to a lucky winner, valued at $300 US in a draw. To enter, follow myDNAge on Instagram here: https://www.instagram.com/mydnage/, and subscribe, rate, and review with a few kind words for my podcast. In order to be considered, proof must be provided via email to sandy@sandyknutrition.ca. North American entries only. To review with a few kind words, go here: https://lovethepodcast.com/sandyknutrition.What is biological age? A trendi...
2021-09-2046 min
熱血科學家的閒話加長（The Excited Scientists' Hot Tea）EP.34 想要長命百歲嗎？方法你願意嘗試嗎？EP.34 想要長命百歲嗎？方法你願意嘗試嗎？
粉絲專頁:https://www.facebook.com/scientists543/
內政部2020年統計，2019年台灣人的平均壽命是80.9歲，男生跟女生平均壽命分別為77.69歲與84.23歲，相差6.54歲！
男性們表示：我也想多活幾年QQ
最近科學家找到方法讓男性增加壽命！方法可能另男性朋友無法接受…
紐西蘭Otago大學解剖學系的Timothy A. Hore教授與加州大學洛杉磯分校（UCLA）的Steve Horvath教授團隊，利用綿羊做了一個實驗，閹割公綿羊，研究人員發現公綿羊壽命延長至60％，其中一名實驗的公綿羊活了16年，而公綿羊的平均壽命是10年，比一般公綿羊多活6年！
不過你願意以蛋換壽，延長壽命嗎？
本集以閹割公綿羊之研究，來聊聊為何可以延長壽命！
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Hosting provided by SoundOn
2021-09-0158 min
Rádio VIVEAGORA#017.1 | Fasting, Keto and Longevity, with gerontologist James Clement (part 2 – English).Welcome to part 2 of our masterclass about fasting, keto and longevity with American biogerontologist James Clement. Please listen to part 1 on our channel as well.
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Disclaimer in Portuguese:
Este programa foi gravado totalmente em inglês. A versão do Youtube conta com legendas em inglês e em português, e em breve disponibilizaremos também uma edição dublada em áudio.
*****
On this episode:
(4:46)
Real-life examples of the association of fasting/CR and longevity: the Okinawans, the Loma Linda adventists and the Mount Athos Mo...
2021-06-211h 09
Julian Dorey Podcast#50 - Riley Horvath: THE FUTURE OF TESLA & ELECTRIC CARS; AR / VR & 3D TECH; AI & DATARiley Horvath is the Co-Founder & CSO of Soar, a spatial technology company that specializes in AR/VR and compression innovation. The company’s mission is to make volumetric technology (like holograms) a central part of our everyday lives. ***TIMESTAMPS*** 9:59 - The timeline of Soar’s progression from the beginning; Covid speeding up adoption across the world 23:59 - “Compression is the road––holograms are the cars”; Making the last 2 percent that changes the world; How to use your iPhone for volumetric experiences; Steve Jobs a...
2021-06-022h 58
Julian Dorey Podcast#50 - Riley Horvath: THE FUTURE OF TESLA & ELECTRIC CARS; AR / VR & 3D TECH; AI & DATARiley Horvath is the Co-Founder & CSO of Soar, a spatial technology company that specializes in AR/VR and compression innovation. The company’s mission is to make volumetric technology (like holograms) a central part of our everyday lives. ***TIMESTAMPS*** 9:59 - The timeline of Soar’s progression from the beginning; Covid speeding up adoption across the world 23:59 - “Compression is the road––holograms are the cars”; Making the last 2 percent that changes the world; How to use your iPhone for volumetric experiences; Steve Jobs and the simplicity of use; The future of shopping in a 3D world 34:47 - Soar is ready to live stre...
2021-06-022h 58
Rádio VIVEAGORA#015 | Genética não é destino (pt II): como ficar mais jovem com o tempo, com a médica integrativa Vania Assaly.Parte II da entrevista com Vania Assaly, diretora da Associação Latinoamericana de Medicina do Estilo de Vida.
Neste episódio:
(9:53) Envelhecimento, ocorrência multifatorial: destino inevitável ou condição tratável? Processos bioquímicos: alterações de energia mitocondrial e células-tronco, acúmulo de radicais livres e proteínas disfuncionais, inflamação crônica.
(16:58) Disfunção celular progressiva, vulnerabilidade genética e escolhas de vida: descartando coringas, uma analogia com o hábito de fumar.
(18:44) Alimentando nosso melhor destino: envelhecer não precisa ser sinônimo de adoecer. Tempo de vida x tempo de saúde.
...
2021-04-261h 45
GondolatkertészetIGAZÁBÓL SZERELEM? ep.8.: A szerelem hálójában (feat. Tari Annamária)Beleszeretsz látatlanul?
Igazából szerelem? - avagy a szerelmesfilmek és az életünk podcast-sorozat, Tari Annamária pszichoterapeuta és Horváth Gergely (Gondolatkertészet) beszélgetései.
Film: A szerelem hálójában (You've Got Mail, 1998)
Írta: Nora Ephron, Delia Ephron, László Miklós
Szereplők: Tom Hanks, Meg Ryan, Steve Zahn, Greg Kinnear, Parker Posey, Dave Chapelle
2021-04-1736 min
AGEISTPaul Hynek: Medically Verified Age Reversal Is Happening NowPaul was in the first medically verifiable trial making people younger. How does it work? Why is this important? Is it even the right thing to do? Why is he doing it again?Is it possible for us to prevent the breakdown of our physical bodies? What is standing in our way from increasing our lifespan? Do we owe it to future generations to take radical steps to live longer?The TRIIM (Thymus Regeneration, Immunorestoration, and Insulin Mitigation) trial is literally making people younger. This trial has proven that we can regrow the...
2021-03-3145 min
ASA PodcastEpisode 85 - Building a Future and Making a DifferenceEpisode 85 – Building a Future and Making a DifferenceJohn Glosek grew up in Pennsylvania loving golf and muscle cars. He built his first engine at 16 and worked in a machine shop, honing his automotive skills in high school. After earning degrees in business management and automotive technology, he followed his passion and now works for Steve Horvath as the Service Manager at Jeno’s Auto Service, Inc. in Littleton, Colorado. John is a thirty-something and one of the next generation of leaders in the automotive service industry. Listen in as John discusses:· How he found his love f...
2021-03-0323 min
State of Identity Podcast Series by LiminalTelos Corporation: The Evolution of CybersecurityHost Cameron D’Ambrosi chats with Steve Horvath, VP of Strategy and Cloud at Telos Corporation. Tune in to learn how the NIST Cybersecurity Framework is applicable across public and private sectors and what mobile technologies have blurred the corporate lines. Horvath gives a candid view into the lessons he's learned in handling systems and compliance issues for federal IT professionals, and the benefits of automated vs. manual compliance in accommodating new cybersecurity regulations.
2021-02-1130 min
Alice in FuturelandDeep Longevity with Alex ZhavoronkovLINKS:Alex Zhavoronkov: https://www.linkedin.com/company/in-silico-medicine-incInsilico Medicine: https://insilico.com/"The Ageless Generation": https://www.amazon.com/Ageless-Generation-Advances-Biomedicine-Transform/dp/0230342205Young.AI Aging APP: https://www.young.ai/Steve Horvath: https://horvath.genetics.ucla.edu/Aging Clock: https://newsroom.ucla.edu/releases/ucla-scientist-uncovers-biological-248950 TRANSCRIPT: ALICE: Today’s question is: How do you measure your age? We are speaking with ALEX ZHAVORONKOV, PhD, expert in artificial intelligence for drug discovery in aging research. Alex is CEO...
2021-01-1316 min
FoundMyFitness#062 Dr. Steve Horvath on epigenetic aging to predict healthspan: the DNA PhenoAge and GrimAge clocksSteve Horvath Steve Horvath, PhD, is a professor of human genetics and biostatistics at UCLA's Fielding School of Public Health Dr. Steve Horvath has analyzed large data sets of DNA methylation profiles to derive an algorithm that accurately predicts a person's chronological age across multiple cells, tissues, and organs, and even mammalian species. He built on this algorithm to develop second-generation clocks that could predict time-to-death among people of the same chronological age, as well as lifespan and healthspan. In this episode, we discuss: (00:00) Introduction and overview (20:24) Horvath Aging Clocks (26:36) Heredity determines agi...
2020-12-221h 33
This Week in FCPAEpisode 232 – the Holidays editionAs TrumpLand continues to live in fantasy and denial, going 1-55 in lawsuits while over 3000 American die daily from Covid-19; Tom and Jay are back to look at some of the top compliance articles and stories which caught their eye this week.
The Vitol FCPA enforcement action. Tom takes a deep dive on the FCPA Compliance and Ethics Blog. Part 1, Part 2, Part 3, Part 4. Mike Volkov has a 3-part series on Corruption Crime and Compliance.
Is the SEC whistleblower program too opaque? Harry Cassin considers in the FCPA Blog.
AML reform and a new whistleblower law. Matt Kelly considers in Radic...
2020-12-1129 min
Quantified Health, Wellness & AgingDeep Biomarkers of Aging and Longevity – EP20: Polina Mamoshina (Deep Longevity)In this twentieth episode, Polina Mamoshina introduces recently launched Deep Longevity, and its app (young.ai).
Read the transcript
Biomarkers of aging are introduced. She explains that they have taken a superior approach by using deep learning instead of machine learning. Aging clocks in general are covered. Finally, she shares her view that transcriptomic and proteonomic clocks are the likely future.
Topics we discussed in this episode
Personal background: Moscow State University, Oxford University, Insilico Medicine hackathon
Bringing Deep Longevity out of stealth, Young.ai companion app
Deep Longevity introduction including company aims
Description of Young.AI app
Biomarkers of...
2020-10-091h 30
Quantified Health, Wellness & AgingEpigenetic Health Monitoring to Reduce Your Future Illness Risk – EP13: Tom Stubbs (Chronomics)In this thirteenth episode, Tom Stubbs, Co-Founder/CEO of Chronomics starts with introducing epigenetics. He describes the technology and expertise that he's brought together to create the only company in the world advancing the forefront of epigenetic biomarkers.
Read the transcript
He explains how their A.I. based health biomarker engine will be used to reduce your risk of future illness.
Topics we discussed in this episode
Focus of Chronomics
Epigenetic sequencing
Epigenetic ideal data type for preventive health
Epigenetics ideal for figuring out age-related and chronic conditions
Genomics and epigenetics provide complimentary data
Histone methylation
DNA methylation
MTHFR gene
...
2020-04-1000 min
Precisione: The HealthcastPrecision Approach to AgingDr. Tom Stubbs, PhD Tom graduated from Oxford University with a 1st in biochemistry and went on to Cambridge University to study the epigenetics of ageing. Tom built the first ageing model in mice, and worked closely with Prof. Steve Horvath of UCLA. He saw the potential for epigenetics and AI to open a new frontier in health sciences, quantifying wellbeing and ageing as never before. Tom founded Chronomics in 2017 to bring epigenetics out of the lab and into people's hands for proactive and preventive health management. What you will learn from this episode:...
2020-01-0532 min